PRODUCTS

BUTYLATED HYDROXYTOLUENE

CAS NUMBER: 128-37-0

EC NUMBER: 204-881-4

MOLECULAR FORMULA: C6H2(OH)(CH3)(C(CH3)3)2

MOLECULAR WEIGHT: 220.35

IUPAC NAME: 2,6-ditert-butyl-4-methylphenol

Butylated Hydroxytoluene is a lab-made chemical that is added to foods as a preservative.
People also use Butylated Hydroxytoluene as medicine.
Butylated Hydroxytoluene is used to treat genital herpes and acquired immunodeficiency syndrome (AIDS).

Some people apply Butylated Hydroxytoluene directly to the skin for cold sores.
Butylated Hydroxytoluene (BHT), also known as dibutylhydroxytoluene, is a lipophilic organic compound, chemically a derivative of phenol, that is useful for its antioxidant properties.

Butylated Hydroxytoluene is an organic chemical composed of 4-methylphenol modified with tert-butyl groups at positions 2 and 6.
Butylated Hydroxytoluene (BHT) inhibits autoxidation of unsaturated organic compounds.

Butylated Hydroxytoluene is used in food, cosmetics and industrial fluids to prevent oxidation and free radical formation.
Butylated Hydroxytoluene is a white crystalline solid
Butylated Hydroxytoluene is a natural product found in Thymus longicaulis, Teucrium leucocladum, and other organisms with data available.

Butylated Hydroxytoluene is widely used to prevent free radical-mediated oxidation in fluids (e.g. fuels, oils) and other materials, and the regulations overseen by the U.S. F.D.A.—which considers BHT to be "generally recognized as safe"—allow small amounts to be added to foods.
Butylated Hydroxytoluene has also been postulated as an antiviral drug, but as of March 2020, use of BHT as a drug is not supported by the scientific literature and it has not been approved by any drug regulatory agency for use as an antiviral.

Natural Occurrence:
Phytoplankton, including the green algae Botryococcus braunii, as well as three different cyanobacteria (Cylindrospermopsis raciborskii, Microcystis aeruginosa and Oscillatoria sp.) are capable of producing BHT as a natural product.
The fruit lychee also produces BHT in its pericarp.
Several fungi (example Aspergillus conicus) living in olives produce Butylated Hydroxytoluene

Industrial Production:
The chemical synthesis of Butylated Hydroxytoluene in industry has involved the reaction of p-cresol (4-methylphenol) with isobutylene (2-methylpropene), catalyzed by sulfuric acid:

CH3(C6H4)OH + 2 CH2=C(CH3)2 → ((CH3)3C)2CH3C6H2OH

Alternatively, Butylated Hydroxytoluene has been prepared from 2,6-di-tert-butylphenol by hydroxymethylation or aminomethylation followed by hydrogenolysis

Applications:
Butylated Hydroxytoluene is listed by the NIH Hazardous Substances Data Bank under several categories in catalogues and databases, such as:
-food additive
-household product ingredient
-industrial additive
-personal care product/cosmetic ingredient
-pesticide ingredient
-plastic/rubber ingredient
-medical/veterinary/research

Food Additive:
Butylated Hydroxytoluene is primarily used as an antioxidant food additive.
In the United States, Butylated Hydroxytoluene is classified as generally recognized as safe (GRAS) based on a National Cancer Institute study from 1979 in rats and mice.

Butylated Hydroxytoluene is used as a preservative ingredient in some foods.
With this usage Butylated Hydroxytoluene maintains freshness or prevents spoilage; it may be used to decrease the rate at which the texture, color, or flavor of food changes.
Some food companies have voluntarily eliminated Butylated Hydroxytoluene from their products or have announced that they were going to phase it out.

Antioxidant:
Butylated Hydroxytoluene is also used as an antioxidant in products such as:
-metalworking fluids
-cosmetics
-pharmaceuticals
-rubber
-transformer oils
-embalming fluid

In the petroleum industry, where Butylated Hydroxytoluene is known as the fuel additive AO-29, it is used in hydraulic fluids, turbine and gear oils, and jet fuels.
Butylated Hydroxytoluene is also used to prevent peroxide formation in organic ethers and other solvents and laboratory chemicals.

Butylated Hydroxytoluene is added to certain monomers as a polymerisation inhibitor to facilitate their safe storage.
Some additive products contain Butylated Hydroxytoluene as their primary ingredient, while others contain the chemical merely as a component of their formulation, sometimes alongside butylated hydroxyanisole (BHA).

Butylated Hydroxytoluene is popular antioxidants used in a wide variety of food products.
Butylated Hydroxytoluene is an additive used as an antioxidant in foods, such as packet cake mixes, potato crisps, salted peanuts, and dehydrated mashed potatoes.

Butylated Hydroxytoluene is closely related synthetic antioxidants used as preservatives in lipsticks and moisturizers, among other cosmetics.
They are also widely used as food preservatives.

Butylated Hydroxytoluene is a lab-made chemical that is added to foods as a preservative.
People also use Butylated Hydroxytoluene as medicine.

Butylated Hydroxytoluene is used to treat genital herpes and acquired immunodeficiency syndrome (AIDS).
Some people apply Butylated Hydroxytoluene directly to the skin for cold sores.

How does Butylated Hydroxytoluene work?
Butylated Hydroxytoluene is an antioxidant.
Butylated Hydroxytoluene may damage the protective outer layer of viral cells.
This may keep the viruses from multiplying and/or doing more damage.

Butylated Hydroxytoluene, commonly known as BHT, is an organic compound that is used in the food, cosmetic, and pharmaceutical industry as an antioxidant.
Butylated Hydroxytoluene is a substituted derivative of phenol.

Butylated Hydroxytoluene helps to prevent the formation of free radicals and oxidation.
When used in food products, Butylated Hydroxytoluene delays oxidative rancidity of fats and oils, and prevents loss of activity of oil-soluble vitamins.

Butylated Hydroxytoluene may be found in pharmaceutical gels, creams and liquid or gelatin capsules, tablets and other pharmaceutical dosage forms.
Butylated Hydroxytoluene or BHT is a stabiliser that can be found in cosmetic products.

Butylated Hydroxytoluene acts as an antioxidant that helps maintain the properties and performance of a product as it is exposed to air (to avoid a change in odor, in color, in texture...).
Butylated Hydroxytoluene is used in various cosmetic products, including certain formulas containing fats or in aqueous emulsions containing certain active ingredients or plant extracts.

Butylated Hydroxytoluene is an antioxidant used in certain products to stabilise and protect the raw materials themselves, and less as an ingredient in and of itself.
Butylated Hydroxytoluene can resist high temperatures (unlike some natural antioxidants):

Butylated Hydroxytoluene is therefore very useful in certain raw material manufacturing processes
Butylated Hydroxytoluene (BHT) is an antioxidant added to plastics such as polyethylene and polypropylene films and polybags to prevent aging

Butylated Hydroxytoluene found in:
-Lip products
-hair products
-makeup
-sunscreen
-antiperspirant/deodorant
-fragrance
-creams

Butylated Hydroxytoluene is used as preservatives in a variety of personal care products.
Both of these chemicals are also used as preservatives in foods.

Butylated Hydroxytoluene also serves as a preservative and antioxidant in pharmaceutical preparations and cosmetic formulations that contain oils and fats.
Dermal exposure to BHA occurs from its use as an antioxidant in commercial products, especially lipstick and eye shadow.

Butylated Hydroxytoluene is a toluene-base ingredient that is used as a preservative in both food and personal care products.
Butylated Hydroxytoluene is a waxy solid consisting for > 98.5% of the active substance, a mixture of 3-tert-butyl-4-hydroxyanisole and 2-tert-butyl-4-hydroxyanisole.

Butylated Hydroxytoluene is intended to be used as an antioxidant in feedingstuffs for all animal species and categories.
Butylated Hydroxytoluene is a chemical commonly used as a preservative in processed foods.

Similar to the synthetic preservative butylated hydroxyanisole (BHA) with which it is often used, BHT is an antioxidant that is soluble in oils and animal fats (it actually has greater solubility than does BHA).
Butylated Hydroxytoluene is a phenolic antioxidant used in the preservation of a wide variety of products, including shelf-stable baked goods.

Butylated Hydroxytoluene is a synthetically aromatic organic compound derived from the reaction of 4-methoxyphenol and isobutylene, catalyzed by sulphuric acid.
Butylated Hydroxytoluene is used in foods that contain oil and fat.

Butylated Hydroxytoluene functions as an antioxidant for preventing spoilage of fats and oils in baked goods by binding oxygen molecules.
Oxygen molecules react preferentially with Butylated Hydroxytoluene rather than oxidizing the fats or oils.

In addition, this action preserves food aroma, color, and flavor.
Add directly to the shortening, as well as to baked goods containing fats, to prevent fat rancidity.

Butylated Hydroxytoluene is not thermally stable.
Butylated Hydroxytoluene evaporates at a temperature below 100°C, and evaporates/decomposes completely at 250°C

Butylated Hydroxytoluene has the least thermal resistance among synthetic antioxidants like PG (propyl gallate), BHA (butylated hydroxyanisole) and TBHQ (tertiary-butyl hydroquinone)
Butylated Hydroxytoluene sometimes appears alone in a food, but often is used in combination with other chemicals that also have an antioxidant activity, including BHA, PG, TBHQ, citric acid, phosphoric acid, and ascorbic acid.
Butylated Hydroxytoluene's effectiveness increases with the addition of synergists.

PHYSICAL PROPERTIES:

-Molecular Weight: 220.35

-XLogP3-AA: 5.3

-Exact Mass: 220.182715385

-Monoisotopic Mass: 220.182715385

-Topological Polar Surface Area: 20.2 Å²

-Physical Description: Butylated Hydroxytoluene is a white crystalline solid.

-Color: White

-Form: Crystalline solid

-Odor: Very faint, musty, occasional cresylic-type odor

-Taste: Tasteless

-Boiling Point: 265 °C

-Melting Point: 71°C

-Flash Point: 127 °C

-Solubility: Insoluble in water and propane- 1,2-diol; Freely soluble in ethanol

-Density: 1.048

-Vapor Density: 7.6

-Vapor Pressure: 0.01 mmHg

-LogP: 5.1

-Viscosity: 3.47

-Index of refraction: 1.4859 at 75 °C/D

Butylated Hydroxytoluene is also used to prevent peroxide formation in organic ethers and other solvents and laboratory chemicals.
Butylated Hydroxytoluene is added to certain monomers as a polymerisation inhibitor to facilitate their safe storage.

Butylated Hydroxytoluene is a lab-made chemical that is added to foods as a preservative.
People also use Butylated Hydroxytoluene as medicine.

Butylated Hydroxytoluene is used to treat genital herpes and acquired immunodeficiency syndrome (AIDS).
Butylated Hydroxytoluene (BHT), also known as dibutylhydroxytoluene, is a lipophilic organic compound, chemically a derivative of phenol, that is useful for its antioxidant properties.
Butylated Hydroxytoluene is an organic chemical composed of 4-methylphenol modified with tert-butyl groups at positions 2 and 6.

CHEMICAL PROPERTIES:

-Hydrogen Bond Donor Count: 1

-Hydrogen Bond Acceptor Count: 1

-Rotatable Bond Count: 2

-Heavy Atom Count: 16

-Formal Charge: 0

-Complexity: 207

-Isotope Atom Count: 0

-Defined Atom Stereocenter Count: 0

-Undefined Atom Stereocenter Count: 0

-Defined Bond Stereocenter Count: 0

-Undefined Bond Stereocenter Count: 0

-Covalently-Bonded Unit Count: 1

-Compound Is Canonicalized: Yes

Butylated Hydroxytoluene (BHT) inhibits autoxidation of unsaturated organic compounds.
Butylated Hydroxytoluene is used in food, cosmetics and industrial fluids to prevent oxidation and free radical formation.

Butylated Hydroxytoluene is a white crystalline solid
Butylated Hydroxytoluene is a natural product found in Thymus longicaulis, Teucrium leucocladum, and other organisms with data available.

Butylated Hydroxytoluene is closely related synthetic antioxidants used as preservatives in lipsticks and moisturizers, among other cosmetics.
Butylated Hydroxytoluene is also widely used as food preservatives.

Butylated Hydroxytoluene is a lab-made chemical that is added to foods as a preservative.
Butylated Hydroxytoluene is used as medicine.

Butylated Hydroxytoluene is used to treat genital herpes and acquired immunodeficiency syndrome (AIDS).
Butylated Hydroxytoluene acts as an antioxidant that helps maintain the properties and performance of a product as it is exposed to air (to avoid a change in odor, in color, in texture...).

Butylated Hydroxytoluene is used in various cosmetic products, including certain formulas containing fats or in aqueous emulsions containing certain active ingredients or plant extracts.
Butylated Hydroxytoluene is an antioxidant used in certain products to stabilise and protect the raw materials themselves, and less as an ingredient in and of itself.

Butylated Hydroxytoluene can resist high temperatures (unlike some natural antioxidants):
Butylated Hydroxytoluene is therefore very useful in certain raw material manufacturing processes
Butylated Hydroxytoluene (BHT) is an antioxidant added to plastics such as polyethylene and polypropylene films and polybags to prevent aging

SYNONYMS:

2,6-Di-tert-butyl-4-methylphenol
Butylated Hydroxytoluene
Butylhydroxytoluene
2,6-Di-tert-butyl-p-cresol
2,6-Di-t-butyl-4-methylphenol
Phenol, 2,6-bis(1,1-dimethylethyl)-4-methyl-
3,5-Di-tert-butyl-4-hydroxytoluene
2,6-ditert-butyl-4-methylphenol
Di-tert-butyl-p-cresol
2,6-Di-tert-butyl-4-cresol
Dibutylated hydroxytoluene
2,6-Bis(1,1-dimethylethyl)-4-methylphenol
Di-tert-butyl-p-methylphenol
o-Di-tert-butyl-p-methylphenol
4-Methyl-2,6-tert-butylphenol
2,6-Di-tert-butyl-1-hydroxy-4-methylbenzene
2,6-Di-tert-butyl-p-methylphenol
2,6-DI-T-BUTYL-P-CRESOL
4-Methyl-2,6-di-tert-butylphenol
Butyl hydroxy toluene
2,6-Di-terc.butyl-p-kresol
4-Hydroxy-3,5-di-tert-butyltoluene
Bht(food grade)
4-Methyl-2,6-di-terc. butylfenol
Butylhydroxytoluenum
1-Hydroxy-4-methyl-2,6-di-tert-butylbenzene
Di-tert-butylcresol
Butylated Hydroxytoluene (bht)
Dbpc(technical grade)
E321
p-Cresol, 2,6-di-tert-butyl-
2,6-ditert-butyl-4-methyl-phenol
2,6-Di-tert-butyl-4-methyl-phenol
2,6-di-tert-butyl-4-methyl phenol
Antioxidant 4
Butylohydroksytoluenu
CCRIS 103
Butylohydroksytoluenu [Polish]
Ionol CP-antioxidant
Di-tert-butyl-p-cresol (VAN)
2,6-Di-terc.butyl-p-kresol
2,6-Di-tert-butyl-4-methylhydroxybenzene
4-Methyl-2,6-di-terc. butylfenol
Lowinox BHT
Nipanox BHT
4-Methyl-2,6-di-t-butyl-phenol
Ionol BHT
Ralox BHT
2, food grade
Butylated Hydroxytoluene [BAN:NF]
Dibutyl-para-cresol
2,6-bis(tert-butyl)-4-methylphenol
butylated-hydroxytoluene
Methyldi-tert-butylphenol
Hydagen DEO
2,6-di-Butyl-para-cresol
2.6-di-t-butyl-p-cresol
2,6-ditert-butyl-p-cresol
p-Cresol,6-di-tert-butyl-
Di-tert-Butylparamethylphenol
2,6-di-tert.butyl-p-cresol
Di-tert-Butyl-4-methylphenol
Butylated Hydroxytoluene (NF)
2,6-bis-tert-butyl-p-cresol
2,6-di-tert-butyl-paracresol
BHT (butylated hydroxytoluene)
2,6-di-tert. butyl-p-cresol
2,6-di-tert.-butyl-p-cresol
2,6-ditertiary-butyl-p-cresol
2,6-di-tert-butyl-para-cresol
2,6-ditertbutyl-4-methylphenol
2,6-di-tert-butyl-4-methylenol
2,6-di-tert-butyl-4methylphenol
2,6-di-tert-butyl4-methylphenol
2,6-di-tertbutyl-4-methylphenol
2,6-ditert.butyl-4-methylphenol
Butylated hydroxyl toluene (BHT)
2,6-Di(tert-butyl)hydroxytoluene
2,6-di(t-butyl)-4-methylphenol
2,6-di-t- butyl-4-methylphenol
3,5-di-t-butyl-4-hydroxytoluene
Butylated Hydroxytoluene (e 321)
Pharmakon1600-01600716
2,1-dimethylethyl)-4-methylphenol
2,6-di-tert-butyl 4-methylphenol
2.6-di-tert-butyl-4-methylphenol
4-methyl-2,6-di-tert.butylphenol
2,6-di-ter-butyl-4-methyl-phenol
2,6-Di-tert.-Butyl4-methylphenol
2,6-ditertiarybutyl-4-methylphenol
2.6-di- t-butyl- 4-methylphenol
2,6 -di-tert-butyl-4-methylphenol
2,6-di(tert-butyl)-4-methylphenol
2,6-Di-tert-butyl-p-cresol, 8CI
2,6-di-tert.-butyl-4-methylphenol
2,6-di-tert-butyl-p-cresol (BHT)
2,6-Di-tert-butyl-para-methylphenol
2,6-di-tert. butyl-4-methyl phenol
2,6-Di-(tert-butyl)-4-methylphenol
Phenol, 2,6-di-tert-butyl-4-methyl-
2,6-Di-tert-butyl-4-methylphenol (BHT)
2,6-Di-tert-butyl-4-methylphenol, 99%
2,6-Di-tert-butyl-4-methylphenol
Butylated Hydroxytoluene
Phenol,6-bis(1,1-dimethylethyl)-4-methyl-
2,6-bis-(1,1-dimethylethyl)-4-methylphenol
4-Methyl-2,6- di(1,1-dimethylethyl)phenol
2,6-Di-tert-butyl-1-hydroxy-4-methyl benzene
Phenol, 3,5-bis(1,1-dimethylethyl)-4-methyl-
2,6-Bis(1,1-dimethylethyl)-4-methylphenol, 9CI
2,6-Di-tert-butyl-4-methylphenol
9FC4DFC8-480D-487C-A74A-2EC9EECE92C4
BENZENE,1,3-DITERT.BUTYL,2-HYDROXY,5-METHYL
2,6-D[(CH3)3C]2C6H2(CH3)OHi-tert-butyl-p-cresol
2,6-Di-tert-butyl-4-methylphenol
2,6-Di-tert-butyl-4-methylphenol
2,6-Di-tert-butyl-4-methylphenol
2,6-Di-tert-butyl-4-methylphenol
3,5-Di-tert-4-butylhydroxytoluene (BHT)
2,6-Di-tert-butyl-4-methylphenol
Butylhydroxytoluene
2,6-Di-tert-butyl-4-methylphenol