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DDMAC (DIDECYLDIMETHYLAMMONIUM CHLORIDE)

DDMAC (Didecyldimethylammonium chloride)

CAS Number: 7173-51-5

SYNONYM: didecyl-dimethylammonium chloride; DDAC; Dimethyldidecylammonium chloride; 1-Decanaminium; N-decyl-N,N-dimethyl-, chloride; Didecyldimethylammonium chloride ; Didecyl dimethyl ammonium chloride; Quaternium-12; Ammonium, didecyldimethyl-, chloride

DDMAC (Didecyldimethylammonium chloride)

CAS Number: 7173-51-5

SYNONYM: didecyl-dimethylammonium chloride; DDAC; Dimethyldidecylammonium chloride; 1-Decanaminium; N-decyl-N,N-dimethyl-, chloride; Didecyldimethylammonium chloride ; Didecyl dimethyl ammonium chloride; Quaternium-12; Ammonium, didecyldimethyl-, chloride; didecyl dimethyl ammonium chloride; N-Decyl-N,N-dimethyl-1-decanaminium chloride; DDMAC; Didecyl dimethyl ammonium chloride; Didecyldimethylammonium chloride; N-decyl-N,N-dimethyldecan-1-aminium chloride; Astop; DDAC; Quaternium 12; Arquad 10; Bardac 22; Britewood Q; Dimethyldidecylammonium chloride; Bio-Dac; Quaternium-12; Quartamin D; 1-Decanaminium, N-decyl-N,N-dimethyl-, chloride; Dodigen 1881; Bardac 2270E; Maquat 4480E; Bardac 2250; Bardac 2280; DIDECYLDIMETHYLAMMONIUMCHLORIDE; DIDECYLDIMONIUM CHLORIDE; BTC 99; DDC 80; didecyl dimethylammonium chloride; BTC 1010; N-Decyl-N,N-dimethyl-1-decanaminium chloride; Ammonium, didecyl dimethyl-, chloride; didecyl(dimethyl)azanium;chloride; Decanaminium, N-decyl-N,N-dimethyl-, chloride (1:1); Acticide DDAC; Acticide DDQ; catiogen DDM; Cation DDC; Catiogen DDM-PG; Asepas 3; Septapav KhS 70; Acticide DDQ 40; Microbiocide B 74; DDC 80; Cation DDC-80; New Des 50; Bardac 2240; K-Sanit BP 80; Arquad 210-80; Dairyland brand chg teat dip; Didecyldimethylammounium chloride; didecyl(dimethyl)azanium chloride; didecyl(dimethyl)ammonium chloride; BTC 2250; AQ 210; Bardac-22; didecyl(dimethyl)ammonium; N-Decyl-N,N-dimethyl 1-decanaminium chloride; 1-Decanaminium,N-decyl-N,N-dimethyl-,chloride; N-Decyl-N,N-dimethyldecan-1-ammonium chloride; Didecyldimethylammonium chloride, analytical standard; Didecyl dimethyl ammonium chloride, 80% aqueous solution; Didecyldimethylammonium chloride; DDAC ; Didecyl dimethyl ammonium chloride ; Didecyldimethylammonium chlorid ; Didecyldimonium chloride ; N-decyl-N,N-dimethyl-1-decanaminium chloride ; Quaternium-12; didecyl(dimethyl)azanium;chloride ; Didecyldimonium chloride; DİDESİL DİMETİL AMONYUM KLORÜR; DİDESİL DİMETİL; AMONYUM KLORÜR; DİDESİL DİMETHYL AMONYUM KLORÜR; DIDESIL DIMETHYL AMONYUM CHLORİDE ; Didecyl dimethyl ammonium chloride; 7173-51-5; Didesil dimetil amonyum klorür; Didecyldimethylammonium chloride; Astop; Quaternium 12; Arquad 10; N-decyl-N,N-dimethyldecan-1-aminium chloride;Britewood Q;Dimethyldidecylammonium chloride; Bio-Dac;Quaternium-12; Odex Q; Quartamin D 10E; Quartamin D 10P; Nissan Cation 2DB; Timbercote 2000; Bardac 22; Slaoff 91;Aliquat 203;DDAC;Querton 210CL; Dodigen 1881; Bardac 2270E; Calgon H 130; Caswell No. 331A; Maquat 4480E; Bardac 2250;Bardac 2280;H 130 (molluscicide); Arquad 210-50; Bio-dac 50-22; Tret-O-Lite XC 507;UNII-JXN40O9Y9B;1-Decanaminium, N-decyl-N,N-dimethyl-, chloride; BTC 99;DDC 80; didecyl dimethylammonium chloride; BTCO 1010; D 10P; BTC 1010; N-Decyl-N,N-dimethyl--decanaminium chloride; Ammonium, Didesil dimetil amonyum klorür; didecyldimethyl-, chloride;DIDECYLDIMETHYLAMMONIUMCHLORIDE;EINECS 230-525-2; EPA Pesticide Chemical Code 069149; didecyl(dimethyl)azanium chloride; CHEBI:79935; didecyl(dimethyl)ammonium chloride;AK112217;W-104509;1-Decanaminium, N-decyl-N,N-dimethyl-, chloride (1:1);20256-56-8 (Parent);Dairyland brand chg teat dip;HSDB 7611; Didesil dimetil amonyum klorür; Bardac-22;Alfa Bergamon (TN);Calgon H130; MolPort-006-109-784;RUPBZQFQVRMKDG-UHFFFAOYSA-M;N-dimethyl-1-decanaminium chloride; Tox21_300598; GK7231; KM1428; MFCD00066262; AKOS015901447; DIDECYLDIMETHYL AMMONIUM CHLORIDE; NCGC00254240-01; 126851-24-9; AN-19339;DA-17489; LP011723;LS-17335;P137;SC-23378;CAS-7173-51-5;KB-201002; RT-004229; FT-0082723; FT-0629457; ST24031400; N-Decyl-N,N-dimethyl 1-decanaminium chloride; Didesil dimetil amonyum klorür; Didesil dimetil amonyum klorür; 1-Decanaminium; Didesil dimetil amonyum klorür; N-dcyl-N,N-dimethyl-,chloride; C15436; D07822; A837307; C-28115; Didecyldimethylammonium chloride, analytical standard; I14-15307; 154765-32-9; 446279-85-27173-51-5; Didecyl dimethyl ammonium chloride; Didecyldimethylammonium chloride; Didesil dimetil amonyum klorür; N-decyl-N,N-dimethyldecan-1-aminium chloride; Astop; Quaternium 12; Arquad 10; Bardac 22; DDAC; Britewood Q; Dim thyldidecylammonium chloride; Bio-Dac; Quaternium-12; Odex Q; Quartamin D 10E; Quartamin D 10P; Nissan Cation 2DB; Timbercote 2000; Slaoff 91; Aliquat 203; Querton 210CL; 1-Decanaminium, N-decyl-N,N-dimethyl-, chloride; Dodigen 1881; Bardac 2270E; Calgon H 130; Caswell No. 331A; Maquat 4480E; Bardac 2250; Bardac 2280; H 130 (molluscicide); Didesil dimetil amonyum klorür; didesil dimetil amonyum klorid; DDAC; DDBAC; DDBAC 50; DDBAC 80; DDAC 80; DDAC 50; didedil dimetil amonyum klorür; didesil dimetil; didehysildiymetyilamiynokloride; didehysildiymetyilamiynoklorit; didehysildiymetyilamiynoklorite; didehsildiymetyilamiynoklorid; didehsildiymetyilamiynokloride; didehsildiymetyilamiynoklorit; didehsildiymetyilamiynoklorite; dideysildiymethyilamiynoklorid; dideysildiymethyilamiynokloride; dideysildiymethyilamiynoklorit; dideysildiymethyilamiynoklorite; didesildiymethyilamiynoklorid; didesildiymethyilamiynokloride; didesildiymethyilamiynoklorit; didesildiymethyilamiynoklorite; didesildimetilamonyumkhlorid; didesil dimetil amonyumkhlorid; didesildimetilamonyumkhloride; dideysildimetilamonyumkhlorid; didesildimethilamonyumkhlorid; dideysildiymetyilamiynokhlorid; dideysildiymetyilamiynokhloride; dideysildiymetyilamiynokhlorit; dideysildiymetyilamiynokhlorite; didesildiymetyilamiynokhlorid; didesildiymetyilamiynokloride; didesildiymetyilamiynokhlorit; didesildiymetyilamiynokhlorite; didehysildiymetyilamiynokhlorid; didehysildiymetyilamiynokhloride; didehysildiymetyilamiynoklorit; didehysildiymetyilamiynokhlorite; didehsildiymetyilamiynoklorid; didehsildiymetyilamiynokhloride; didehsildiymetyilamiynoklorit; didehsildiymetyilamiynokhlorite; DIDESILDIMETILAMONYUMKHLORID; DIDESIL DIMETIL AMONYUMKHLORID; DIDESILDIMETILAMONYUMKHLORIDE; DIDEYSILDIMETILAMONYUMKHLORID; DIDESILDIMETHILAMONYUMKHLORID; DIDEYSILDIYMETYILAMIYNOKHLORID; DIDEYSILDIYMETYILAMIYNOKHLORIDE; DIDEYSILDIYMETYILAMIYNOKHLORIT; DIDEYSILDIYMETYILAMIYNOKHLORITE; DIDESILDIYMETYILAMIYNOKHLORID; DIDESILDIYMETYILAMIYNOKLORIDE; DIDESILDIYMETYILAMIYNOKHLORIT


Didecyldimethylammonium chloride(DDAC) is an antiseptic/disinfectant that is used in many biocidal applications. It causes disruption of intermolecular interactions and dissociation of lipid bilayers. It is a broad spectrum bactericidal and fungicidal and can be used as disinfectant cleaner for linen, recommended for use in hospitals, hotels and industries. It is also used in gynaecology, surgery, ophthalmology, pediatrics, OT, and for the sterilization of surgical instruments, endoscopes and surface disinfection. In mice this disinfectant was found to cause infertility and birth defects when combined with Alkyl (60% C14, 25% C12, 15% C16) dimethyl benzyl ammonium chloride (ADBAC),[3][4]. These studies contradict the older toxicology data set on quaternary ammonia compounds which was reviewed by the U.S. Environmental Protection Agency (U.S. EPA) and the EU Commission.[5]

Properties
Chemical formula    C22H48ClN
Molar mass      362.08 g/mol
Appearance      liquid
Density    0.87 g/cm3 (20 °C)

Didecyldimethylammonium chloride(DDMAC) cas 7173-51-5
Assay: 80%,50%, 40%
Appearance: Colorless to pale yellow clear liquid
Capacity: 560mt/YEAR
Packaging: 180kg/drum 900kg/drum
Sample: available
Categories: Bactericide, Surfactant

Description
Didecyldimethylammonium chloride (DDAC) Details

Chemical Name: Didecyldimethylammonium chloride / DDMAC
CAS No.: 7173-51-5
Molecular Formula: C22H48ClN
Molecular Weight:362.08
MolecularStructure:Didecyldimethylammonium chloride Structure
Appearance:Colorless to pale yellow clear liquid

Didecyldimethylammonium chloride Typical Properties
Appearance    Colorless to pale yellow clear liquid
Active Assay    ≥80﹪
Free amine and its salt    ≤1.5%
Ph(10% aqueous)    5-9
 
Didecyldimethylammonium chloride(DDAC) Usage

1) Water treatment products and Surfactant
2)Be used as a bactericide, disinfectant, better than benzalkonium chloride

Didecyldimethylammonium chloride (DDAC) Packaging and Shipping
Packing: 200kg/drum 1000kg/drum

Didecyldimethylammonium chloride (DDAC) Storage
1.It is forbidden to mix with toxic and harmful substances.
2.The product has certain moisture absorption.
3.It should be stored in a sealed way in low temperature, dry, cool and ventilated condition.
4.The shelf life is not open for 24 months.

Descriptions
Didecyldimethylammonium chloride is a broad spectrum algaecide and fungicide used in many biocidal applications. It cause  disruption of intermolecular interactions and dissociation of lipid bilayers. 

Applications
Algaecides and biocides for cooling water systems. In textile dyeing & printing industry as algaecide,  softener, anti-static auxiliary. Disinfections for aquiculture and poultry house

3D Status    
Conformer generation is disallowed since MMFF94s unsupported atom valence, too flexible, mixture or salt
IUPAC Name    
didecyl(dimethyl)azanium;chloride ; Didecyldimonium chloride
Molecular Formula    
C22H48ClN
Physical Description    
Liquid
Color/Form    
Colorless crystals
Clear yellow liquid /commercial aqueous solution
Solid powder of slight yellowish color at 20 °C
Odor    
Mushroom-like odor
Ethanolic odor
Boiling Point    
>180 °C; decomposes before boiling at 1 atm /OECD Guideline 103/
Melting Point    
94-100 °C /OECD Guideline 102/
Solubility    
In water, 0.65 g/L at 20 °C /OECD Guideline 115/
In water, 0.39 g/L at 25 °C /critical micelle concentration/
Soluble in acetone; extremely soluble in benzene; insoluble in hexane
In isopropanol: 827, 797 and 836 g/L at 10, 20 and 30 °C, respectively; in-octanol: 248 g/L at 20 °C; in hexane: 0.000424 g/L at 10 °C
Density
0.87 at 20 °C /OECD Guideline 109/
Vapor Pressure
<4.3X10-5 mm Hg at 25 °C, <1.1X10-5 mm Hg at 20 °C /OECD Guideline 104/
Decomposition
When heated to decomposition it emits very toxic fumes of /nitrogen oxides, ammonia, and hydrogen chloride/.
Corrosivity
Anion is corrosive ... treated wood has the disadvantage of being incompatible with many paints and coatings
pH    
pH = 6.8 to 6.9 at 25 °C in a 29.5% water solution
Surface Tension    
25.82 mN/m at 20 °C, 1 g/L solution
Other Experimental Properties    
Extremely hygroscopic
Colorless liquid. Density: 0.870 g/mL; pH 7.81 /Bardac 2280/
Therapeutic Uses    
EXPL THER A double blind trial with 2 concentrations of the combination Didecyldimethylammonium chloride (Hoe S-2922, Bardac-22) with prednicarbate for the treatment of impetiginized eczema in 30 hospitalized patients is described. The study did not reveal any significant differences in effectiveness, although a trend in favor of the higher concentration was apparent.
Agrochemical Category    
Microbiocide, Fungicides
ATC Code    
D - Dermatologicals
D08 - Antiseptics and disinfectants
D08A - Antiseptics and disinfectants
D08AJ - Quaternary ammonium compounds
D08AJ06 - Didecyl dimethyl ammonium chloride
Absorption, Distribution and Excretion    
DDMAC (40% aqueous in both radiolabled (14C) and nonradiolabled form), used in a definitive pharmacokinetic study to determine absorption, distribution and excretion and was administered orally (single dose), by gavage, to Charles River CD Rats (Crl CD(SD)Br--5/sex/group) in 3 dose regimens: 1) A single low dose (5 mg/kg), 2) a repeated low dose in diet containing 34 ppm "cold" in the feed daily for 14 days, followed by a 5 mg/kg dose of (14C)]-DDCA (9.01 mCi/mmole, and 99% radiochemical purity) or 3) a single high dose of 50 mg/kg. Excretion of radioactivity was shown to occur primarily in the feces (89-99%), some in urine (<2.5%), and an insignificant amount was expired. Highly ionic DDAC is not readily absorbed from the GI tract...

Metabolism/Metabolites
DDMAC (40% aqueous in both radiolabled (14C) and nonradiolabled form), used in a definitive pharmacokinetic study to determine absorption, distribution and excretion and was administered orally (single dose), by gavage, to Charles River CD (Crl CD(SD)Br--5/sex/group) ... . In the addendum the metabolic profile was determined in a 2 step experiment. First, another group of rats (10 male Charles River CD (Crl CD(SD)Br) were treated with (14C)-DDAC at 50 mg/kg in order to obtain enough (14C) residues to use as standards. The (14C) metabolites were characterized by TLC, HPLC and MS. The second part of the experiment involved using the "standard" metabolic profiles to analyze the metabolites from feces samples obtained in the initial study. It was shown that metabolism tends to be sex specific. Females metabolize the parent compound more so than males. Metabolism, which may be microbial in nature, involved the oxidation of the 2 decyl side chains to form hydroxy and hydroxyketo derivatives. Modification of methyl substituents was not evident.
Use and Manufacturing    
Overview    
IDENTIFICATION: Didecyldimethylammonium chloride is a clear, yellow liquid, yellowish powder or colorless crystals. It has a mushroom-like odor. It is moderately soluble in water. USE: Didecyldimethylammonium chlorideis used as an antimicrobial. Applications include commercial and residential where it is used on walls, floors, tables, toilets and fixtures. Solutions are introduced into humidifiers, ultrasonic tanks, reverse osmosis units, cooling systems and water storage tanks. It is used to disinfectant egg shells, milking equipment and udders, agricultural tools and vehicles. It is used as a sanitizer for swimming pools, and decorative ponds and fountains. It is a wood preservative. Didecyldimethylammonium chloride is registered for these antimicrobial uses by the U.S. EPA Office of Pesticide Programs. EXPOSURE: Exposure to Didecyldimethylammonium chloride is most often from skin or eye contact, but can also include inhalation or ingestion. When Didecyldimethylammonium chloride is released to the environment, it will absorb to surfaces. It will move slowly or not at all in soil. It will not volatilize from soil or water surfaces. It will moderately build up in aquatic organisms. Microbes in the environment will break it down. Didecyldimethylammonium chloride released to air will be in or on particles that eventually fall to the ground. RISK: Didecyldimethylammonium chlorideis corrosive and can cause irreversible eye damage and skin burns. When using aerosol applications, swallowing or breathing in mists can be fatal. To prevent these short-term effects, the U.S. EPA Office of Pesticide Programs requires that personal protective equipment like chemical resistant gloves and apron be used, when applying certain products containing didecyl dimethyl ammonium chloride. The U.S. EPA Office of Pesticide Programs determined that Didecyldimethylammonium chlorideis not likely to cause cancer, reproductive effects, or birth defects. This determination was based on results from studies with laboratory animals. The potential for Didecyldimethylammonium chloride to cause cancer in humans has not been assessed by the U.S. EPA IRIS program, the International Agency for Research on Cancer, or the U.S. National Toxicology Program 13th Report on Carcinogens. (SRC)
Use Classification    
Agrochemicals -> Fungicides
Cosmetics -> Antistatic; Emulsifying; Hair conditioning; Surfactant

Uses Didecyldimethylammonium chloride
Absorbent    Agent for soaking up liquid (product use or application unknown)    CPCat Cassette
Adhesive    General adhesives and binding agents for a variety of uses    CPCat Cassette
Adhesive, water_based, consumer_use    Term applied when the only information the source indicates is 'consumer' or 'consumer product' ; also applied to terms that the source indicates are f     CPCat Cassette
Adsorbent    Adhesion of molecules to a surface    CPCat Cassette
Agricultural Didecyl dimethyl ammonium chloride    Relating to agricultural, including the raising and farming of animals and growing of crops    CPCat Cassette
Agricultural, animal    Related to animals (but non-veterinary) e.g., animal husbandry, farming of animals/animal production, raising of animals for food or fur, animal feed, products for household pets     CPCat Cassette
Agricultural, animal, cattle, dairy    Related to dairy cattle, the operation of dairy facilities, or manufacture of dairy products    CPCat Cassette
Agricultural, crop    Products used on crops, or related to the growing of crops    CPCat Cassette
Antimicrobial    Didecyldimethylammonium chloride Type of pesticide used to destroy or inhibit the growth of disease-causing mechanisms, can be impregnated into clothing    CPCat Cassette
Aquaculture    Aquafarming, or the farming of aquatic organisms    CPCat Cassette
Beverage, food_service    Related to food and beverage service activities    CPCat Cassette
Building_construction    Related to the building or construction process for buildings or boats (includes activities such as plumbing and electrical work, bricklaying, etc)    CPCat Cassette
Child_use    Didecyldimethylammonium chloride Related to products specifically designed for children (e.g. toys, children's cosmetics, etc)    CPCat Cassette
Cleaning_washing    Related to all forms of cleaning/washing, including cleaning products used in the home, laundry detergents, soaps, de-greasers, spot removers, etc; modifiers included when specific information is known, such as drycleaning, laundry, soap, window/floor, etc     CPCat Cassette
Cleaning_washing, bathroom, consumer_use    Term applied when the only information the source indicates is 'consumer' or 'consumer product' ; also applied to terms that the source indicates are for consumer use, yet the descriptor term is ambivalent about usage (e.g., cleaning_washing products may be for industrial or consumer use, when the source indicates consumer use, the consumer_use term is also applied) - see appendix for full list of unambiguous consumer related terms plus ambiguous consumer related terms which if indicated are labeled with 'consumer_use'     CPCat Cassette
Cleaning_washing, carpet, consumer_use    Term applied when the only information the source indicates is 'consumer' or 'consumer product' ; also applied to terms that the source indicates are f     CPCat Cassette
Cleaning_washing, consumer_use    Term applied when the only information the source indicates is 'consumer' or 'consumer product' ; also applied to terms that the source indicates are f     CPCat Cassette
Cleaning_washing, disinfectant    General disinfectants/sanitizing agnets, disinfectants related to drugs (modified by 'drug'), and disinfectants used in drinking water, or animal feed (modified by 'drinking_water' and 'feed')     CPCat Cassette
Cleaning_washing, drycleaning    Products or chemicals found or used in drycleaning establishments    CPCat Cassette
Cleaning_washing, flooring    Flooring materials (carpets, wood, vinyl flooring), or related to flooring such as wax or polish for floors    CPCat Cassette
Cleaning_washing, flooring, consumer_use    Term applied when the only information the source indicates is 'consumer' or 'consumer product' ; also applied to terms that the source indicates are f     CPCat Cassette
Cleaning_washing, fur    Related to the raising of fur animals, or fur products (such as fur apparel)    CPCat Cassette
Cleaning_washing, laundry, consumer_use    Term applied when the only information the source indicates is 'consumer' or 'consumer product' ; also applied to terms that the source indicates are for consumer use, yet the descriptor term is ambivalent about usage (e.g., cleaning_washing products may be for industrial or consumer use, when the source indicates consumer use, the consumer_use term is also applied) - see appendix for full list of unambiguous consumer related terms plus ambiguous consumer related terms which if indicated are labeled with 'consumer_use'     CPCat Cassette
Cleaning_washing, textile    Textiles used for clothing or furniture upholstery, processes related to textiles (e.g.     CPCat Cassette
Cleaning_washing, textile, detergent    Detergents with wide variety of applications; modifiers included when known    CPCat Cassette
Cleaning_washing, tools, consumer_use    Term applied when the only information the source indicates is 'consumer' or 'consumer product' ; also applied to terms that the source indicates are for consumer use, yet the descriptor term is ambivalent about usage (e.g., cleaning_washing products may be for industrial or consumer use, when the source indicates consumer use, the consumer_use term is also applied) - see appendix for full list of unambiguous consumer related terms plus ambiguous consumer related terms which if indicated are labeled with 'consumer_use'     CPCat Cassette
Colorant Didecyl dimethyl ammonium chloride    Term used for colorants, dyes, or pigments; includes colorants for drugs, textiles, personal care products (cosmetics, tatoo inks, hair dye), food colorants, and inks for printing; modifiers included when application is known     CPCat Cassette
Conductive    Conductive materials or agents (able to conduct something, typically heat or electricity)    CPCat Cassette
Construction    General construction (as opposed to those things labeled building_construction); i.e. when source only indicates 'construction,' construction of roads, or engineering     CPCat Cassette
Consumer_use    Term applied when the only information the source indicates is 'consumer' or 'consumer product' ; also applied to terms that the source indicates are for consumer use, yet the descriptor term is ambivalent about usage (e.g., cleaning_washing products may be for industrial or consumer use, when the source indicates consumer use, the consumer_use term is also applied) - see appendix for full list of unambiguous consumer related terms plus ambiguous consumer related terms which if indicated are labeled with 'consumer_use'     CPCat Cassette
Disinfectant Didecyldimethylammonium chloride    General disinfectants/sanitizing agnets, disinfectants related to drugs (modified by 'drug'), and disinfectants used in drinking water, or animal feed (modified by 'drinking_water' and 'feed')     CPCat Cassette
Drug, human, hygiene, biocidal    Pharmaceutical related    CPCat Cassette
Drug, veterinary, biocide    Chemical which can deter, destroy, or control a harmful organism by chemical or biological means (type of pesticide)    CPCat Cassette
Facility, drycleaning, laundry    Laundry products (such as cleaning/washing agents), or laundry facilities    CPCat Cassette
Facility, food_production    Related to food production (restaurants, catering, etc)    CPCat Cassette
Facility, food_service    Related to food and beverage service activities    CPCat Cassette
Facility, laundry    Laundry products (such as cleaning/washing agents), or laundry facilities    CPCat Cassette
Feed, animal, disinfectant    General disinfectants/sanitizing agnets, disinfectants related to drugs (modified by 'drug'), and disinfectants used in drinking water, or animal feed (modified by 'drinking_water' and 'feed')     CPCat Cassette
Filler    Fillers for paints, textiles, plastics, etc    CPCat Cassette
Fishing    Related to the activity of fishing    CPCat Cassette
Fluid_property_modulator    Includes antifoaming agents, coagulating agents, dispersion agents, emulsifiers, flotation agents, foaming agents, viscosity adjustors, etc    CPCat Cassette
Food_additive, preservatives    Includes preservatives used in cosmetics, film, wood preserving agents, foods, etc (note food preservatives are also indicated as food_additive)    CPCat Cassette
Food_contact    Includes food packaging, paper plates, cutlery, small appliances such as roasters, etc.; does not include facilities that manufacture food    CPCat Cassette
Food_service    Related to food and beverage service activities    CPCat Cassette
Fragrance Didecyldimethylammonium chloride    Fragrances or odor agents, can be used in home products (cleaners, laundry products, air fresheners) or similar industrial products; usage indicated when known; more specific modifiers included when known     CPCat Cassette
Fragrance, consumer_use    Term applied when the only information the source indicates is 'consumer' or 'consumer product' ; also applied to terms that the source indicates are for consumer use, yet the descriptor term is ambivalent about usage (e.g., cleaning_washing products may be for industrial or consumer use, when the source indicates consumer use, the consumer_use term is also applied) - see appendix for full list of unambiguous consumer related terms plus ambiguous consumer related terms which if indicated are labeled with 'consumer_use'     CPCat Cassette
Hunting    Related to the activity of hunting    CPCat Cassette
Industrial, adhesive    General adhesives and binding agents for a variety of uses    CPCat Cassette
Industrial, cleaning_washing    Related to all forms of cleaning/washing, including cleaning products used in the home, laundry detergents, soaps, de-greasers, spot removers, etc; modifiers included when specific information is known, such as drycleaning, laundry, soap, window/floor, etc     CPCat Cassette
Industrial_manufacturing        CPCat Cassette
Inert    Didecyldimethylammonium chloride    CPCat Cassette
Manufacturing, beverage    Beverages for human consumption (e.g., juice, water, alcohol), or related to beverages for human consumption (e.g. machinery for production of beverages, or facilities serving beverages)     CPCat Cassette
Manufacturing, building_material, wood    Wood used as a building material, wood preservatives    CPCat Cassette
Manufacturing, chemical    General term used only when the only information known from the source is 'chemical,' typically related to manufacturing of chemicals, or laboratory chemicals     CPCat Cassette
Manufacturing, cigarettes    Chemicals in cigarettes, or tobacco related products, or related to the manufacturing of tobacco products    CPCat Cassette
Manufacturing, cleaning_washing, polish    Car wax/polish, floor wax, general polishing agents, polish for metals, plastics, rubber, lacquers, leather, furniture, etc    CPCat Cassette
Manufacturing, detergent    Detergents with wide variety of applications; modifiers included when known    CPCat Cassette
Manufacturing, drug    Drug product, or related to the manufacturing of drugs; modified by veterinary, animal, or pet if indicated by source    CPCat Cassette
Manufacturing, export    Related to manufacturing for export (additional information unknown)    CPCat Cassette
Manufacturing, food    Food for human consumption, does not include food additives (see food_additive); also includes manufacture of food, facilities related to food (with appropriate modifiers)     CPCat Cassette
Manufacturing, food, meat    Related to the farming of meats (including cattle, poultry, swine), and the manufacturing of meat for human consumption    CPCat Cassette
Manufacturing, furniture    Furniture, or the manufacturing of furniture (can include chairs and tables, and more general furniture such as mattresses, patio furniture, etc.)    CPCat Cassette
Manufacturing, metals    Related to metals - manufacturing of metals, casting of metals, production of metals, surface treatment of metals, etc    CPCat Cassette
Manufacturing, paint    Various types of paint for various uses, modifiers included when more information is known    CPCat Cassette
Manufacturing, paper    Related to the manufcturing of pulp or paper products, or paper products in general    CPCat Cassette
Manufacturing, personal_care, cosmetics, perfume    Fragrance used as a personal care product    CPCat Cassette
Manufacturing, plastics    Plastic products, industry for plastics, manufacturing of plastics, plastic additives (modifiers included when known)    CPCat Cassette
Manufacturing, rubber    Rubber products (e.g. tires) and their manufacture    CPCat Cassette
Manufacturing, soap    Soaps, includes personal care products for cleansing the hands or body, and soaps/detergents for cleaning products, homes, etc    CPCat Cassette
Manufacturing, textile    Textiles used for clothing or furniture upholstery, processes related to textiles (e.g. softeners, antiwrinkle agents), or the processing/manufacturing of textiles     CPCat Cassette
Paint Didecyldimethylammonium chloride    Various types of paint for various uses, modifiers included when more information is known    CPCat Cassette
Paint, volatile_organic    Volatile and semivolative organic compounds    CPCat Cassette
Paint, water_based    Modifier included when source indicates the product is water based    CPCat Cassette
Personal_care, cosmetics, hair_dye, colorant    Term used for colorants, dyes, or pigments; includes colorants for drugs, textiles, personal care products (cosmetics, tatoo inks, hair dye), food colorants, and inks for printing; modifiers included when application is known     CPCat Cassette
Pesticide Didecyldimethylammonium chloride    Substances used for preventing, destroying or mitigating pests    CPCat Cassette
Pesticide, active_ingredient    Active ingredients in a product (often active ingredients in pesticide, if so also tagged with 'pesticide')    CPCat Cassette
Pesticide, antimicrobial    Type of pesticide used to destroy or inhibit the growth of disease-causing mechanisms, can be impregnated into clothing    CPCat Cassette
Pesticide, antimicrobial, active_ingredient    Active ingredients in a product (often active ingredients in pesticide, if so also tagged with 'pesticide')    CPCat Cassette
Pesticide, bactericide    Type of pesticide that kills bacteria    CPCat Cassette
Pesticide, biocide, active_ingredient    Active ingredients in a product (often active ingredients in pesticide, if so also tagged with 'pesticide')    CPCat Cassette
Pesticide, active_ingredient    Active ingredients in a product (often active ingredients in pesticide, if so also tagged with 'pesticide')    CPCat Cassette
Pesticide, antimicrobial    Type of pesticide used to destroy or inhibit the growth of disease-causing mechanisms, can be impregnated into clothing    CPCat Cassette
Pesticide, antimicrobial, active_ingredient    Active ingredients in a product (often active ingredients in pesticide, if so also tagged with 'pesticide')    CPCat Cassette
Pesticide, bactericide    Type of pesticide that kills bacteria    CPCat Cassette
Pesticide, biocide, active_ingredient    Active ingredients in a product (often active ingredients in pesticide, if so also tagged with 'pesticide')    CPCat Cassette
Pesticide, active_ingredient    Active ingredients in a product (often active ingredients in pesticide, if so also tagged with 'pesticide')    CPCat Cassette
Pesticide, antimicrobial    Type of pesticide used to destroy or inhibit the growth of disease-causing mechanisms, can be impregnated into clothing    CPCat Cassette
Pesticide, antimicrobial, active_ingredient    Active ingredients in a product (often active ingredients in pesticide, if so also tagged with 'pesticide')    CPCat Cassette
Pesticide, bactericide    Type of pesticide that kills bacteria    CPCat Cassette
Pesticide, biocide, active_ingredient    Active ingredients in a product (often active ingredients in pesticide, if so also tagged with 'pesticide')    CPCat Cassette
Solvent, paint_remover    Paint and varnish removers    CPCat Cassette
Sports_equipment    Sporting equipment (e.g. soccer balls, basketball rims, fishing rods, tents, boating accessories, fitness equipment, boats/boating equipment, etc)    CPCat Cassette
Surface_treatment    Surface treatments for metals, hardening agents, corrosion inhibitors, polishing agents, rust inhibitors, water repellants, etc (surfaces to be applied to often not indicated in source description)     CPCat Cassette
Water_treatment     Didecyldimethylammonium chloride Includes water softeners, lime removers, and the products used in the process of the collection, purification, and distribution of water    CPCat Cassette

For Didecyldimethylammonium chloride (USEPA/OPP Pesticide Code: 069149) ACTIVE products with label matches. /SRP: Registered for use in the U.S. but approved pesticide uses may change periodically and so federal, state and local authorities must be consulted for currently approved uses./
Algaecide, bacteriocide, fungicide, fungistat, microbiocide, microbiostat disinfectant, viricide, tuberculocide, molluscide, sanitizer, wood preservative, deodorant, and insecticide.

Use Category    Use Sites
Industrial Processes and Water Systems    Industrial recirculating water systems, cooling water, disposal water, oil field operations, oil field water flood or salt water disposal
Swimming Pools    Swimming pools, outside spas, whirlpools, hot tubs
Aquatic Areas    Greenhouses/nurseries, golf courses, recreational parks, amusement parks, universities, cemeteries
Wood Treatment    Pressure treatment, double vacuum, and dip/spray surface treatment
Agricultural Premise and Equipment    Hatcheries, swine/poultry/turkey farms, dressing plants, farrowing barns, mushroom farm, citrus farm, animal housing facilities, florists/flower shops, greenhouses, nurseries
Residential and Public Access Premise    Homes, mobile homes, cars, trucks, campgrounds, playgrounds, trailers, campers, boats, public facilities
Medical Premise and Equipment    Hospitals, health care facilities, medical/dental offices, nursing homes, medical research facilities, autopsy rooms, newborn nurseries, acute care institutions, alternate care institutions, funeral homes, mortuaries, day care facilities, sick rooms
Commercial Institutional and Industrial Premise and Equipment    Athletic/recreational facilities, exercise facilities, schools, colleges, dressing/locker rooms, transportation terminals, libraries, motel, hotels, barber/beauty salons, health clubs, emergency vehicles, correctional facilities, factories, commercial florists, convenience stores, offices, commercial and institutional laundry mats
Food Handling/Storage Establishments Premises and Equipment    Restaurants, food service establishments, food storage, handling, processing plants/facilities, beverage processing plants, bars, cafeterias, supermarkets, dairies, egg processing plants, institutional kitchens, breweries, fast food operations, rendering plants, school lunchrooms, packing plants

General purpose disinfectant, sanitizer; mildew preventative in commercial laundries; water treatment in cooling towers and oil field flood waters; wood preservative.
Didecyldimethylammonium chloride is an active ingredient in a large number of disinfectant products registered with EPA and labeled with a claim to inactivate "avian influenza A" viruses on hard, non-porous surfaces.

Industry Uses Didecyldimethylammonium chloride     
Pesticide Formulation
Processing aids, specific to petroleum production
Surface active agents
Consumer Uses    Didecyldimethylammonium chloride     
Automotive care products
Cleaning and furnishing care products
Fuels and related products
Non-TSCA use
Personal care products

Formulations/Preparations    Didecyldimethylammonium chloride    
The National Pesticide Information Retrieval System (NPIRS) identifies 74 companies with active labels for products containing the chemical didecyldimethylammonium chloride. To view the complete list of companies, product names and percent Didecyldimethylammonium chloride in formulated products click the following url and enter the CAS Registry number in the Active Ingredient field.
This chemical is listed as an Extended High Production Volume (EHPV). Chemicals listed as EHPV were produced in or imported into the U.S. in >1 million pounds according to the 2002 Toxic Substances Control Act (TSCA) Inventory Update. The EHPV program is a voluntary initiative that allows companies to demonstrate that adequate screening data exist for organic HPV chemicals.
Non-confidential 2012 Chemical Data Reporting (CDR) information on the production and use of chemicals manufactured or imported into the United States. Chemical: 1-Decanaminium, N-decyl-N,N-dimethyl-, chloride. National Production Volume: 2,228,752 lb/yr.

Industry Processing Sectors
All other chemical product and preparation manufacturing
Oil and gas drilling, extraction, and support activities
Soap, cleaning compound, and toilet preparation manufacturing
EPA TSCA Commercial Activity Status
1-Decanaminium, N-decyl-N,N-dimethyl-, chloride (1:1)
Used in waterborne copper-based wood preservative products ... introduced in New Zealand in 1978 ... to counteract basidiomycetes and soft rot fungi ... not suitable for wood in contact with the ground used in Canada in antisapstain formulations for treatment of freshly sawn lumber, in disinfectant formulations, and as a molluscicide. use as a molluscicide at pipe ends ... adding / didecyldimethylammonium chloride / to the intake and bentonite clay as an absorbant in the outfall.

Analytic Laboratory Methods    
A competitive enzyme-linked immunosorbent assay (ELISA), based on polyclonal antibodies, was developed to measure Didecyldimethylammonium chloride (DDMAC). The anti-DDMAC polyclonal antibodies recognized the free Didecyldimethylammonium chloride in an indirect competitive ELISA. With this assay, the detection limit was 8 ug/mL, and 50% inhibition was reached at 29 ug/mL. The antibodies recognized the aliphatic chain of the Didecyldimethylammonium chloridemolecule. They also cross-reacted with compounds having 1012-carbon aliphatic chains, such as fatty acids, fatty alcohols, or n-decyl alpha-D-glucoside. The competitive ELISA was used to measure the amount of Didecyldimethylammonium chloride present in several available antisapstain products. For example, with F2A (15% DDMAC), a linear relationship between the ELISA results and the theoretical values was observed in a range between 20 and 50 ppm didecyldimethylammonium chloride . The measured concentrations of DDMAC in other commercial products, F2, NP-1, and Bardac 2280, were in close agreement with the values reported by the /manufacturer/.
HPLC is used to resolve and quantitate Didecyldimethylammonium chloride (DDMAC) from the extracts of four species of wood. Didodecyl dimethyl ammonium bromide (DoDAB) is used as an internal standard. The extract is injected directly onto the column with no sample cleanup step. An evaporative light-scattering detector is used to detect the quaternary ammonium compounds in amounts ranging from 250 ng to 5 mug injected on the column. Baseline resolution of the DDMAC and DoDAB is achieved regardless of wood species. Average extraction efficiency for Didecyldimethylammonium chloride is 85% or better for all four species.
Skin, Eye, and Respiratory Irritations    
... The primary dermal effects that have been reported are rash, burning sensation, numbness, and itching. ... /Quaternary ammonium compounds/
Cleanup Methods    
If a spill occurs, clean it up promptly. Don't wash it away. Instead, sprinkle the spill with sawdust, vermiculite, or kitty litter. Sweep it into a plastic garbage bag, and dispose of it as directed on the pesticide product label./Residential uses/
After Applying a Pesticide, Indoors or Outdoors. To remove pesticide residues, use a bucket to rinse tools or equipment three times, including any containers or utensils that you used when mixing the pesticide. Then pour the rinsewater into the pesticide sprayer and reuse the solution by applying it according to the pesticide product label directions. After applying any pesticide wash your hands and any other parts of your body that may have come in contact with the pesticide..To prevent tracking pesticides inside, remove or rinse your boots or shoes before entering your home. Wash any clothes that have been exposed to a lot of pesticide separately from your regular wash. /Residential uses/
Disposal Methods    HelpNew Window
SRP: The most favorable course of action is to use an alternative chemical product with less inherent propensity for occupational harm/injury/toxicity or environmental contamination. Recycle any unused portion of the material for its approved use or return it to the manufacturer or supplier. Ultimate disposal of the chemical must consider: the material's impact on air quality; potential migration in soil or water; effects on animal and plant life; and conformance with environmental and public health regulations.
Pesticide Disposal: Pesticide wastes are acutely hazardous. Improper disposal of excess pesticide, spray mixture, or rinsate is a violation of Federal Law. If these pesticides cannot be disposed of by use according to label instructions, contact your State Pesticide or Environmental COntrol Agency, or the Hazardous Waste representative at the nearest EPA Regional Office for guidance. /Bardac Wood Preservative 80/
Container DIsposal: Plastic Container: Triple rinse (or equivalent). Then offer for recycling or reconditioning, or puncture and dispose of in a sanitary landfill, or, if allowed by state and local authorities by burning. If burned, stay out of smoke. Metal Container: Triple rinse (or equivalent). Then offer for recycling or reconditioning, ... or by other procedures approved by state and local authorities.
Do not discharge effluent containing this product into lakes, streams, ponds, estuaries, oceans, or other waters unless in accordance with the requirements of a National Pollution Discharge Elimination System (NPDES) permit and the permitting authority has been notified in writing prior to the discharge. Do not discharge effluent containing this product to sewer systems without previously notifying the local sewage treatment plant authority. For guidance contact your State Water Board or Regional Office of the EPA.
For Once Through Cooling Water Towers: This product must be deactivated prior to discharge of the National Pollution Discharge Elimination System outfall. TO deactivate, use bentonite Clay at minimum ration of 5 ppm clay to 1 ppm of product.
Safe Disposal of Pesticides. The best way to dispose of small amounts of excess pesticides is to use them - apply them - according to the directions on the label. If you cannot use them, ask your neighbors whether they have a similar pest control problem and can use them. If all of the remaining pesticide cannot be properly used, check with your local solid waste management authority, environmental agency, or health department to find out whether your community has a household hazardous waste collection program or a similar program for getting rid of unwanted, leftover pesticides. These authorities can also inform you of any local requirements for pesticide waste disposal. /Residential uses/
Safe Disposal of Pesticides. An empty pesticide container can be as hazardous as a full one because of residues left inside. Never reuse such a container. When empty, a pesticide container should be rinsed carefully three times and the rinsewater thoroughly drained back onto the sprayer or the container previously used to mix the pesticide. Use the rinsewater as a pesticide, following label directions. Replace the cap or closure securely. Dispose of the container according to label instructions. Do not puncture or burn a pressurized container like an aerosol - it could explode. Do cut or puncture other empty pesticide containers made of metal or plastic to prevent someone from reusing them. Wrap the empty container and put it in the trash after you have rinsed it. /Residential uses/
SRP: Wastewater from contaminant suppression, cleaning of protective clothing/equipment, or contaminated sites should be contained and evaluated for subject chemical or decomposition product concentrations. Concentrations shall be lower than applicable environmental discharge or disposal criteria. Alternatively, pretreatment and/or discharge to a permitted wastewater treatment facility is acceptable only after review by the governing authority and assurance that "pass through" violations will not occur. Due consideration shall be given to remediation worker exposure (inhalation, dermal and ingestion) as well as fate during treatment, transfer and disposal. If it is not practicable to manage the chemical in this fashion, it must be evaluated in accordance with EPA 40 CFR Part 261, specifically Subpart B, in order to determine the appropriate local, state and federal requirements for disposal.
Preventive Measures
Precautionary Statements for all Manufacturing Use Products (based on concentration of active ingredients): Do not get in eyes, on skin, or on clothing. Do not breathe vapor or spray mist. Wear a dust/ filtering respirator (MSHA/ NIOSH approval number TC-21C) ora a NIOSH approved respirator with any N, R, P, or HE filter. WEar goggles or faceshield, rubber gloves, and protective clothing when handling. Wash thoroughly with soap and water after handling. Remove contaminated clothing and wash before reuse.
SRP: Contaminated protective clothing should be segregated in a manner such that there is no direct personal contact by personnel who handle, dispose, or clean the clothing. The completeness of the cleaning procedures should be considered before the decontaminated protective clothing is returned for reuse by the workers. Contaminated clothing should not be taken home at the end of shift, but should remain at employee's place of work for cleaning.
Individuals who enter pressue treatment cylinders and other related equipment that are contaminated with the wood treatment solution ... must wear protective clothing including overalls, jacket, gloves and boots impervious to the wood treatment formulation. Federal, state and local confined space entry procedures must be followed. /Bardac Wood Preservative 80/
Applicators must not eat or drink, or use tobacco products during those parts of the application process that may expose them to the wood treatment formulation. /Bardac Wood Preservative 80/
Discard clothing and other absorbent materials that have been drenched or heavily contaminated. Do not reuse them. Follow manufacturer;s instructions for cleaning/maintaining protective equipment. In no such instructions exist for washables, use detergent and hot water. Keep and wash protective equipment separate from other laundry. /Bardac Wood Preservative 80/
Application Restrictions for Products Used in Swimming Pools/Spas: Do not apply when swimmers are in the immediate vicinity (EPA recommends a 15 minute reentry interval).
End Use Products Intended for Commercial, Institutional, Industrial, and Agricultural Uses: Hatcheries: 2 hr Reentry Interval (REI) for fogging applications. Food Processing Plants: 2 hr REI for fogging applications and a minimum of 4 air exchanges per hr in the facility.
For hard nonpourous surfaces in institutional/commercial food handling facilities, after disinfection, a potable water rinse is required. Do not use on dishes, glasses, and utensils. Do not use to disinfect appliances, refrigerator interiors, and microwave oven interiors.
Wear the items of protective clothing the label requires: for example, non-absorbent gloves (not leather or fabric), rubber footwear (not canvas or leather), a hat, goggles, or a dust-mist filter. If no specific clothing is listed, gloves, long-sleeved shirts and long pants, and closed shoes are recommended. You can buy protective clothing and equipment at hardware stores or building supply stores. /Residential uses/
Indoor Applications. If the label directions permit, leave all windows open and fans operating after the application is completed. If the pesticide product is only effective in an unventilated (sealed) room or house, do not stay there. Put all pets outdoors, and take yourself any your family away from treated areas for at least the length of time prescribed on the label. Apply most surface sprays only to limited areas such as cracks; don't treat entire floors, walls, or ceilings. Don't let pesticides get on any surfaces that are used for food preparation. Wash any surfaces that may have pesticide residue before placing food on them. /Residential uses/
Indoor Applications. When using total release foggers to control pests, use no more than the amount needed and to keep foggers away from ignition sources (ovens, stoves, air conditioners, space heaters, and water heaters, for example). Foggers should not be used in small, enclosed places such as closets and cabinets or under tables and counters. /Residential uses/
Outdoor Applications. Never apply pesticides outdoors on a windy day (winds higher than 10 mph). Position yourself so that a light breeze does not blow pesticide spray or dust into your face. /Residential uses/
SRP: Local exhaust ventilation should be applied wherever there is an incidence of point source emissions or dispersion of regulated contaminants in the work area. Ventilation control of the contaminant as close to its point of generation is both the most economical and safest method to minimize personnel exposure to airborne contaminants. Ensure that the local ventilation moves the contaminant away from the worker.
Storage Conditions
Do not contaminate water, food or feed by storage or disposal. /Bardac Wood Preservative 80/
Do not use or store near heat or open flame /Bardac Wood Preservative 80/
Treated lumber must be stored under cover, or indoors, or at least 100 feet from any pond, lake, stream, wetland, or river ... Treated lumber stored outdoors within 100 feet ... must be covered with plastic or surrounded by a berm. If a berm is used around the site, it must consist of impermeable material (clay, asphalt, concrete) and be of sufficient height to prevent runoff during heavy rainfall events.
Safe Storage of Pesticides. Always store pesticides in their original containers, complete with labels that list ingredients, directions for use, and first aid steps in case of accidental poisoning. Never store pesticides in cabinets with or near food, animal feed, or medical supplies. Do not store pesticides in places where flooding is possible or in places where they might spill or leak into wells, drains, ground water, or surface water. /Residential uses/

Allowable Tolerances
Residues of the following chemical substances are exempted from the requirement of a tolerance when used in accordance with good manufacturing practice as ingredients in an antimicrobial pesticide formulation, provided that the substance is applied on a semi-permanent or permanent food-contact surface (other than being applied on food packaging) with adequate draining before contact with food. ... (c) The following chemical substances when used as ingredients in an antimicrobial pesticide formulation may be applied to: Food-processing equipment and utensils. 1-Decanaminium, N-decyl-N,N-dimethyl-, chloride is included on this list. Limit: When ready for use, the end-use concentration is not to exceed 200 ppm of active quaternary compound.
Personal Protective Equipment (PPE)
For End Use Products Intended for Commercial, Institutional, Industrial, Agricultural, and Residential Uses: PPE requirements are dependent on the Acute Toxicity Daft submitted to EPA to support the end use product registration /and the specific product label should be consulted/
FIFRA Requirements
Residues of the following chemical substances are exempted from the requirement of a tolerance when used in accordance with good manufacturing practice as ingredients in an antimicrobial pesticide formulation, provided that the substance is applied on a semi-permanent or permanent food-contact surface (other than being applied on food packaging) with adequate draining before contact with food. ... (c) The following chemical substances when used as ingredients in an antimicrobial pesticide formulation may be applied to: Food-processing equipment and utensils. 1-Decanaminium, N-decyl-N,N-dimethyl-, chloride is included on this list. Limit: When ready for use, the end-use concentration is not to exceed 200 ppm of active quaternary compound.
The Agency has completed its assessment of the dietary, residential, occupational, drinking water, and ecological risks associated with the use of pesticide products containing the active ingredient DDAC. Based on a review of these data and on public comments on the Agency's assessments for the active ingredient DDAC, the Agency has sufficient information on the human health and ecological effects of DDAC to make decisions as part of the tolerance reassessment process under FFDCA and reregistration process under FIFRA, as amended by FQPA. The Agency has determined that DDAC-containing products are eligible for reregistration provided that: (i) current data gaps and confirmatory data needs are addressed; the risk mitigation measures outlined in this document are adopted; and (iii) label amendments are made to reflect these measures. ... Based on its evaluation of DDAC, the Agency has determined that DDAC products, unless labeled and used as specified in this document, would present risks inconsistent with FIFRA. Accordingly, should a registrant fail to implement the risk mitigation measure identifie in this document, the Agency may take regulatory action to address the risk concerns from the use of DDAC. If all changes outlined in this document are incorporated into the product labels, then all current risks for DDAC will be substantially mitigated for the purposes of this determination. Once an Endangered Species assessment is completed, further changes to these registrations may be necessary as explained in Section III of this document.
As the federal pesticide law FIFRA directs, EPA is conducting a comprehensive review of older pesticides to consider their health and environmental effects and make decisions about their continued use. Under this pesticide reregistration program, EPA examines newer health and safety data for pesticide active ingredients initially registered before November 1, 1984, and determines whether the use of the pesticide does not pose unreasonable risk in accordance to newer saftey standards, such as those described in the Food Quality Protection Act of 1996. Pesticides for which EPA had not issued Registration Standards prior to the effective date of FIFRA '88 were divided into three lists based upon their potential for human exposure and other factors, with List B containing pesticides of greater concern than those on List C, and with List C containing pesticides of greater concern than those on List D. Didecyldimethylammonium chloride is found on List C. Case No: 3003; Pesticide type: fungicide, herbicide, antimicrobial; Case Status: OPP is reviewing data from the pesticide's producers regarding its human health and/or environmental effects, or OPP is determining the pesticide's eligibility for reregistration and developing the RED document.; Active ingredient (AI): didecyldimethylammonium chloride; Data Call-in (DCI) Date(s): 10/13/95; AI Status: The producers of the pesticide have made commitments to conduct the studies and pay the fees required for reregistration, and are meeting those commitments in a timely manner.
Interactions
The bactericidal activity of a quaternary ammonium salt, didecyldimethylammonium chloride (DDAC), was depressed by the presence of soap, sodium laurate (NaLA): the minimum lethal concentration (MLC) of DDAC against Staphylococcus aureus was 63 and 250 ug/mL in the absence and presence of 0.01% NaLA, respectively. The neutralizing effect was studied in relation with the mode of action of DDAC. The apparent uptake of DDAC by the cell was not repressed by NaLA's presence when compared to that in its absence. The solution of NaLA showed alkaline pH, but the biocidal activity of DDAC was higher at pH 11 than at pH 7. Although the presence of NaLA had no significant effect on DDAC's action on increasing the turbidity of the cell suspension, the mixture of these reagents alone without cells exhibited some turbidity. From these findings it is deduced that NaLA can form a less active complex with DDAC by both ionic and hydrophobic interactions...
Toxicity Summary
IDENTIFICATION AND USE: Didecyl dimethylammonium chloride is a clear yellow liquid with an ethanolic odor. It is used as an algaecide, bacteriocide, fungicide, fungistat, microbiocide, microbiostat disinfectant, viricide, tuberculocide, molluscide, sanitizer, wood preservative, deodorant, and insecticide. It has been tested for treatment of impetiginized eczema patients in combination with prednicarbate. HUMAN EXPOSURE AND TOXICITY: Nausea, headache, and sore throat are the primary systemic effects that have been reported. The primary dermal effects that have been reported are rash, burning sensation, numbness, and itching. A case report of dermatitis from detergent/disinfectant was described. A 24 year old woman, who had worked in a hospital for 2 years, presented with a 2 month history of dermatitis of the dorsum of the hands and wrists. Patch testing showed she was positive for didecyldimethylammonium chloride and bis-(aminopropyl)-laurylamine which was present in detergents/disinfectants. According to the EPA classification didecyl dimethylammonium chloride is not likely to be carcinogenic to humans. ANIMAL STUDIES: In animals it is a severe eye irritant, severe dermal irritant, but not a sensitizer. It was of moderate acute oral toxicity in rodents, with possible effects on the liver and central nervous system being seen. In rats no adverse oncogenic effects were observed, however, there were treatment-related changes in both sexes in the mesenteric lymph node (blood filled sinuses, hemosiderosis and hystiocytosis) and bile duct hyperplasia at 1500 ppm. There were no developmental effects in rats. In developmental study in rabbits an increased number of dead fetuses/litter and decreased fetal body weight at 10.0 mg/kg was observed. In the Ames test, with or without the microsomal activation (S-9 fraction), didecyl dimethylammonium chloride was not mutagenic to Salmonella typhimurium tester strains. It was not mutagenic in vivo in rats, in Chinese hamster ovary cells, and did not produce unscheduled DNA synthesis. ECOTOXICITY STUDIES: Swimming performance decreased significantly in juvenile rainbow trout. Significant decreases in larval growth and survival were noted at all tested concentrations and in all sturgeon age groups. The larval stage was usually more sensitive than the fry stage. Acute toxicity tests with fertilized eggs were unsuccessful. Developmental stage altered the sensitivity of coho salmon to Bardac 2280, with alevins being approximately twice as sensitive as smolts.
Antidote and Emergency Treatment
/SRP:/ Immediate first aid: Ensure that adequate decontamination has been carried out. If patient is not breathing, start artificial respiration, preferably with a demand valve resuscitator, bag-valve-mask device, or pocket mask, as trained. Perform CPR if necessary. Immediately flush contaminated eyes with gently flowing water. Do not induce vomiting. If vomiting occurs, lean patient forward or place on the left side (head-down position, if possible) to maintain an open airway and prevent aspiration. Keep patient quiet and maintain normal body temperature. Obtain medical attention. /Poisons A and B/
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