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CAS: 151-21-3
MF: C12H25NaO4S
MW: 288.38
EINECS: 205-788-1
Disponil SLS 101, sometimes written sodium laurilsulfate, is an organic compound with the formula CH3(CH2)11OSO3Na.
Disponil SLS 101 is an anionic surfactant used in many cleaning and hygiene products.
This compound is the sodium salt of the 12-carbon an organosulfate.
Disponil SLS 101's hydrocarbon tail combined with a polar "headgroup" give the compound amphiphilic properties that make it useful as a detergent.
Disponil SLS 101 is also component of mixtures produced from inexpensive coconut and palm oils.
Disponil SLS 101 is a common component of many domestic cleaning, personal hygiene and cosmetic, pharmaceutical, and food products, as well as of industrial and commercial cleaning and product formulations.
Disponil SLS 101 is an anionic surfactant naturally derived from coconut and/or palm kernel oil.
Disponil SLS 101 usually consists of a mixture of sodium alkyl sulfates, mainly the lauryl.
Disponil SLS 101 lowers surface tension of aqueous solutions and is used as fat emulsifier, wetting agent, and detergent in cosmetics, pharmaceuticals and toothpastes.
Disponil SLS 101 is also used in creams and pastes to properly disperse the ingredients and as research tool in protein biochemistry.
Disponil SLS 101 also has some microbicidal activity.
Disponil SLS 101 is an anionic detergent used to solubilize and denature proteins in protein extraction and SDS-PAGE.
Disponil SLS 101 is useful in electrophoretic separation of proteins and lipids.
Disponil SLS 101 is also used in a variety of hybridization and molecular biology techniques.
Disponil SLS 101 is effective in both ionic and anionic conditions.
Disponil SLS 101 unravels proteins by binding to peptide chains and imparting a negative charge on the protein; this causes the protein to unfold eliminating shape as a factor for gel separation.
Disponil SLS 101 is an anionic surfactant, and is a typical representative of sulphate-based surfactant.
Disponil SLS 101 is abbreviated as SDS, and also known as AS, K12, coco alcohol sulfate, sodium lauryl sulfate and foaming agent.
The commercial products are usually white to light yellow crystalline powder.
Disponil SLS 101 is non-toxic, slightly soluble in alcohol, insoluble in chloroform and ether, soluble in water, and has good anionic and nonionic complex compatibility.
Disponil SLS 101 has good emulsibility, foamability, and foaming, infiltrating, decontaminating and dispersing properties.
Disponil SLS 101 is abundant in foams and quickly biodegradable, and has solubility next only to fatty alcohol polyoxyethylene ether sodium sulphate (abbreviated as AES).
Disponil SLS 101 is not sensitive to alkali and hard water, but its stability is inferior to general sulfonate under acidic conditions and is close to AES.
Disponil SLS 101 is not favorable to exceed 95 °C upon long-term heating, and its irritation is at the middle level among surfactants, with an irritation index of 3.3 for a 10% solution, which is higher than AES and lower than sodium dodecyl benzene sulfonate (abbreviated as LAS).
There is no evidence that Disponil SLS 101 is carcinogenic, but high doses may indeed irritate the skin.
However, in general sanitary products the concentration is limited when used as a forming agent, and is in line with national standards.
So there is no need to concern.
Disponil SLS 101 is a major component of detergent.
Disponil SLS 101 is usually used in the DNA extraction process to separate DNA after protein denaturation.
Disponil SLS 101 is often misread as sodium dodecyl sulfonate.
Disponil SLS 101 is widely used as a foaming agent in toothpaste, soap, shower gel, shampoo, detergent and cosmetics.
95% of personal care products and household cleaning products contain Disponil SLS 101.
There is certain universality of confusion and misuse for them, both of which belong to the anionic surfactants and the English abbreviations are both SDS.
Disponil SLS 101 is also called sodium lauryl sulfate (abbreviated as SLS), belongs to sulfate salt and has a molecular weight of 288.38.
Disponil SLS 101 is a white or light yellow crystal, and is easily soluble in water.
Disponil SLS 101 belongs to sulfonate, has a molecular weight of 272.38, and differs with the structure of sodium dodecyl sulfate in that Disponil SLS 101 lacks one oxygen atom and the carbon atom is directly connected to the sulfur atom.
Disponil SLS 101 Chemical Properties
Melting point: 204-207 °C (lit.)
Density: 1.03 g/mL at 20 °C
FEMA: 4437 | SODIUM LAURYL SULFATE
Fp: >100°C
Storage temp.: 2-8°C
Solubility : H2O: 0.1 M, clear to nearly clear, colorless to slightly yellow
Form: Powder or Crystals
Color: White to pale yellow
Odor: Slight fatty odour
PH: 6-9 (10g/l, H2O, 20℃)
PH Range: 7.2
Water Solubility: ca. 150 g/L (20 ºC)
λmax: λ: 260 nm Amax: 0.3
λ: 280 nm: Amax: 0.2
Merck: 14,8636
BRN: 3599286
InChIKey: DBMJMQXJHONAFJ-UHFFFAOYSA-M
CAS DataBase Reference: 151-21-3(CAS DataBase Reference)
EPA Substance Registry System: Sodium lauryl sulfate (151-21-3)
Uses
Disponil SLS 101 has excellent detergency, emulsification and foaming power, can be used as detergents and textile auxiliaries, and is also used as an anionic surfactant, toothpaste foaming agent, mine fire extinguishing agents, foaming agents for fire extinguishers, emulsion polymerization emulsifiers, emulsifying and dispersing agents for medical use, shampoo and other cosmetic products, wool detergent, detergent for silky class fine fabrics and flotation agent for metal beneficiation.
Disponil SLS 101 used as foaming agents; emulsifying agents; and anionic surfactants.
Disponil SLS 101 is used for cakes, drinks, proteins, fruits, fruit juice, and edible oil, and so on.
Disponil SLS 101 is used as surfactants, detergents, foaming agents, and wetting agents, and so on.
Disponil SLS 101 is used as relatively low-level ion-pairing reagents, and is cheaper than sodium heptanesulfonate and sodium pentanesulfonate when less demanding.
Disponil SLS 101 is used as raw material for modifying materials.
Disponil SLS 101 is used as additives in capillary electrophoresis analysis and is generally used as molar solution.
Disponil SLS 101 is also used in other analysis such as flow column analysis.
Disponil SLS 101 is an emulsifier and whipping aid that has a solubility of 1 g in 10 ml of water.
Disponil SLS 101 functions as an emulsifier in egg whites.
Disponil SLS 101 is used as a whipping aid in marshmallows and angel food cake mix.
Disponil SLS 101 also functions to aid in dissolving fumaric acid.
Wetting agent, detergent, especially in the textile industry.
Electrophoretic separation of proteins and lipids.
Ingredient of toothpastes.
Production method
Sulphur trioxide method: the reaction apparatus is a vertical reactor.
At 32 °C nitrogen gas is introduced into the reactor through the gas vents at a flow rate of 85.9 L·min-1.
At 82.7 kPa lauryl alcohol is introduced at a flow rate of 58 g·min-1.
The liquid sulfur trioxide is fed into flash evaporator at 124.1 kPa, the flash temperature is maintained at 100 °C, and sulfur trioxide flow rate is controlled to be 0.907 2 kg·h-1. Disponil SLS 101 is then rapidly quenched to 50 °C, injected into the aging device and left for 10 to 20 min, and finally injected into the neutralization kettle and neutralized with a base.
The neutralizing temperature is controlled at 50 °C.
The material is discharged when the pH value is adjusted to 7 to 8.5, to obtain a liquid product which is spray dried to give a solid product.
Batch method: lauryl alcohol is charged into reaction kettle and pre-heated to 30 °C.
Then chlorosulfonic acid 0.03 mol in excess than the theoretical amount is sprayed into the alcohol under high speed agitation.
The reaction temperature was controlled at 30 to 35 °C.
After the sulfation reaction, it is injected into the neutralization kettle and neutralized with 30% lye to a pH value of 7 to 8.5, and finally bleached with 0.4% (weight) hydrogen peroxide.
Disponil SLS 101 is spray dried to give a solid.
Disponil SLS 101 can also be formulated into solutions according to quality standard.
Continuous method: the reaction apparatus is tubular reactor.
Lauryl alcohol is initially saturated with hydrogen chloride.
Lauryl alcohol at a flow rate of 334 g·min-1 and hydrogen chloride at a flow rate of 40.5 g·min-1 are fed into saturation chamber through gauge.
Then the solution of lauryl alcohol with hydrogen chloride is fed into reactor at 21.4 °C to react with chlorosulfonic acid.
After the reaction is subjected to gas-liquid separation, the sulfated product flows from the bottom of the separator into neutralization kettle.
Disponil SLS 101 is neutralized with 30% sodium hydroxide at 50 °C to give a liquid product, which is spray dried to give a solid product.
Reactivity Profile
Disponil SLS 101 is incompatible with strong oxidizers.
Disponil SLS 101 is also incompatible with cationic materials and with acids with pH below 2.5.
Salts, basic, such as Disponil SLS 101, are generally soluble in water.
The resulting solutions contain moderate concentrations of hydroxide ions and have pH's greater than 7.0.
They react as bases to neutralize acids.
These neutralizations generate heat, but less or far less than is generated by neutralization of the bases in reactivity group 10 (Bases) and the neutralization of amines.
They usually do not react as either oxidizing agents or reducing agents but such behavior is not impossible.
Pharmaceutical Applications
Disponil SLS 101 is an anionic surfactant employed in a wide range of nonparenteral pharmaceutical formulations and cosmetics.
Disponil SLS 101 is a detergent and wetting agent effective in both alkaline and acidic conditions.
In recent years Disponil SLS 101 has found application in analytical electrophoretic techniques: SDS (sodium dodecyl sulfate) polyacrylamide gel electrophoresis is one of the more widely used techniques for the analysis of proteins; and Disponil SLS 101 has been used to enhance the selectivity of micellar electrokinetic chromatography (MEKC).
Synonyms
Sodium dodecyl sulfate
151-21-3
SODIUM LAURYL SULFATE
Sodium dodecylsulfate
Sodium lauryl sulphate
Sodium dodecyl sulphate
Dodecyl sodium sulfate
Neutrazyme
Sodium n-dodecyl sulfate
Irium
Sulfuric acid monododecyl ester sodium salt
Dodecyl sulfate sodium salt
Dodecyl sulfate, sodium salt
Anticerumen
Duponal
Duponol
Gardinol
Sodium monododecyl sulfate
Dreft
Aquarex methyl
Duponol methyl
Solsol needles
Stepanol methyl
Duponol waqa
Stepanol wac
Stepanol waq
Duponol qx
Richonol af
Perlandrol L
Perlankrol L
Sipex sb
Sipex sd
Standapol wa-ac
Stepanol me dry
Duponol Me
Richonol A
Richonol C
Sintapon L
Duponol C
Maprofix LK
Standapol WAQ
Stepanol ME
Stepanol WA
Akyposal SDS
Carsonol SLS
Maprobix NEU
Maprofix NEU
Maprofix WAC
Aquarex ME
Dupanol WAQ
Duponol QC
Duponol WA
Duponol WA dry
Duponol WAQ
Empicol LPZ
Hexamol SLS
Melanol CL
Duponal WAQE
Duponol WAQE
Duponol WAQM
Lanette Wax-S
Sterling wa paste
Conco sulfate WA
Conco sulfate WN
Nikkol SLS
Orvus WA Paste
Sipex OP
Sipex SP
Sipex UB
Sipon LS
Sipon PD
Sipon WD
Detergent 66
Montopol La Paste
Sipon LSB
Maprofix WAC-LA
Sterling WAQ-CH
Cycloryl 21
Cycloryl 31
Stepanol WA Paste
Conco Sulfate WAG
Conco Sulfate WAN
Conco Sulfate WAS
Quolac EX-UB
Odoripon Al 95
sodiumdodecylsulfate
Avirol 118 conc
Cycloryl 580
Cycloryl 585N
Lauyl sodium sulfate
Maprofix 563
Sinnopon LS 95
Stepanol T 28
Sodium laurilsulfate
Steinapol NLS 90
Empicol LS 30
Empicol LX 28
Lauryl sodium sulfate
Melanol CL 30
NALS
Rewopol NLS 30
Standapol waq special
Standapol was 100
Sinnopon LS 100
Stepanol WA-100
Carsonol SLS Special
Standapol 112 conc
Stepanol ME Dry AW
Avirol 101
Emersal 6400
Monogen Y 100
Carsonol SLS Paste B
sodium;dodecyl sulfate
Stepanol methyl dry aw
Berol 452
Emal 10
EMAL O
Sipon LS 100
n-Dodecyl sulfate sodium
Sodium monolauryl sulfate
Monododecyl sodium sulfate
Sodiumlauryl ether sulfate
Lauryl sulfate sodium salt
Conco sulfate WA-1200
Conco sulfate WA-1245
Dehydag sulfate GL emulsion
Product no. 75
Product no. 161
MFCD00036175
Emulsifier no. 104
Texapon k 12 p
CHEBI:8984
P and G Emulsifier 104
Sodium lauryl sulfate ether
SLS
Sodium Laurylsulfate
NSC-402488
Texapon K 1296
NCI-C50191
Laurylsulfuric Acid Sodium Salt
Natriumalkyl(C8-C20)-sulfate
Dodecyl alcohol, hydrogen sulfate, sodium salt
Dodecylsulfuric Acid Sodium Salt
Sodium lauryl sulfate, synthetic
Finasol osr2
Incronol SLS
Natriumlaurylsulfat
368GB5141J
NCGC00091020-03
E487
Jordanol SL-300
Finasol osr(sub 2)
Dodecyl sulfate sodium
Monagen Y 100
Perklankrol ESD 60
Caswell No. 779
Natrium laurylsulfuricum
DSSTox_CID_6031
DSSTox_RID_77989
DSSTox_GSID_26031
12738-53-3
12765-21-8
1334-67-4
Laurylsiran sodny [Czech]
Lauryl sulfate, sodium salt
Dehydrag sulfate gl emulsion
Dehydag sulphate GL emulsion
Laurylsiran sodny
Rhodapon UB
Sodium lauryl sulfate 30%
CAS-151-21-3
CCRIS 6272
Lauryl sulfate sodium
HSDB 1315
Sodium lauryl sulfate, dental grade
EINECS 205-788-1
EPA Pesticide Chemical Code 079011
NSC 402488
CP 75424
Empicol
AI3-00356
UNII-368GB5141J
Sodium lauryl sulfate [JAN:NF]
sodiumlauryl sulfate
Sulfuric acid monododecyl ester sodium salt (1:1)
sodium dodecylsulphate
Sodium dedecyl sulfate
Sodium-dodecyl-S-SDS
IPC-SDS
sodium n-dodecyl sulphate
Sodium Lauryl Sulfate NF
sodium monododecyl sulphate
lauryl sulphate sodium salt
EC 205-788-1
dodecyl sulphate sodium salt
SCHEMBL1102
sodium dodecyl sulfate (sds)
CHEMBL23393
sodium dodecyl sulphate (sds)
Sodium dodecyl sulphate solution
DTXSID1026031
dodecyl sulfuric acid sodium salt
Dodecyl sulphuric acid sodium salt
Sodium lauryl sulfate (JP17/NF)
SODIUM LAURYL SULFATE [II]
SODIUM LAURYL SULFATE [MI]
BCP30594
CS-B1770
SODIUM LAURYL SULFATE [FCC]
SODIUM LAURYL SULFATE [JAN]
Tox21_111059
Tox21_201614
Tox21_300149
BDBM50530482
SODIUM LAURILSULFATE [MART.]
SODIUM LAURYL SULFATE [HSDB]
SODIUM LAURYL SULFATE [INCI]
SODIUM LAURYL SULFATE [VANDF]
AKOS015897278
AKOS025147308
Tox21_111059_1
DB00815
Dodecyl sulfuric acid ester sodium salt
SODIUM LAURYL SULFATE [USP-RS]
SODIUM LAURYL SULFATE [WHO-DD]
NCGC00091020-01
NCGC00091020-02
NCGC00254225-01
NCGC00259163-01
NCGC00274082-01
AS-14730
SODIUM LAURILSULFATE [EP IMPURITY]
Lauryl Sulfate, Sodium Salt (25% Aq.)
SODIUM LAURILSULFATE [EP MONOGRAPH]
D1403
FT-0603358
FT-0700721
I0352
S0588
D01045
F16341
S-4600
S-4601
Sodium dodecyl sulfate, 10% solution in water
SODIUM DODECYL SULFATE BIOTECH GRD 100G
Q422241
Sodium n-dodecyl sulfate, 98%, for electrophoresis
Sodium n-dodecyl sulfate (SDS), 20% aqueous solution
F0001-0539
Z1695728983
Sodium dodecylsulfate;Sodium lauryl sulphate;Dodecyl sodium sulfate
Dodecyl sodium sulfate, Dodecyl sulfate sodium salt, Lauryl sulfate sodium salt, SDS, Sodium lauryl sulfate
