Folate and folic acid are forms of vitamin B9 used for deficiency and to prevent pregnancy complications. Many foods contain folate or have folic acid added.
Since 1998, folic acid has been added to cold cereals, flour, breads, pasta, bakery items, cookies, and crackers, as required by federal law. Foods that are naturally high in folate include leafy vegetables, okra, asparagus, certain fruits, beans, yeast, mushrooms, animal liver and kidney, orange juice, and tomato juice.
Folic acid is also available as a supplement, and is often used in combination with other B vitamins.
Folic acid is used for preventing and treating low blood levels of folate (folate deficiency) and high blood levels of homocysteine (hyperhomocysteinemia). People who are pregnant or might become pregnant take folic acid to prevent serious birth defects such as spina bifida.
Folic acid is also used for many other conditions including depression, stroke, decline in memory and thinking skills, and many others.
Folic acid is the man-made version of the vitamin folate (also known as vitamin B9).
Folic acid helps the body make healthy red blood cells and is found in certain foods.
Folic acid is used to:
treat or prevent folate deficiency anaemia
help your unborn baby's brain, skull and spinal cord develop properly to avoid development problems (called neural tube defects) such as spina bifida
help reduce side effects from methotrexate, a medicine used to treat severe arthritis, Crohn's disease or psoriasis
Folic acid is available on prescription and comes as tablets or as a liquid you swallow.
About folic acid
Folic acid is a B vitamin. Our bodies use it to make new cells. Think about the skin, hair, and nails. These–and other parts of the body – make new cells each day.
Folic acid is the synthetic (that is, not generally occurring naturally) form of folate used in supplements and in fortified foods such as rice, pasta, bread, and some breakfast cereals
The terms “folate” and “folic acid” are often used interchangeably, even though they are different. Folate is a general term to describe many different types of vitamin B9.
Types of folate can include
5, 10-methylenetetrahydrofolate (5, 10-Methylene-THF)
5-methyltetrahydrofolate (5-Methyl-THF or 5-MTHF)
Food fortification is a way to add vitamins or minerals, or both, to foods. Some rice, pasta, bread, and breakfast cereals are fortified with folic acid. These foods are labeled “enriched.” Folic acid is a specific type of folate that does not generally occur naturally.
Folic acid is ideal to use for food fortification.
Folic acid is more stable than types of natural food folate. Heat and light can easily break down types of natural food folate.
Folic acid is better suited for food fortification because many fortified products, such as bread and pasta, are cooked.
Folic acid (vitamin B-9) is important in red blood cell formation and for healthy cell growth and function.
Folic acid is crucial during early pregnancy to reduce the risk of birth defects of the brain and spine.
Folic acid is found mainly in dark green leafy vegetables, beans, peas and nuts. Fruits rich in folate include oranges, lemons, bananas, melons and strawberries. The synthetic form of folate is folic acid.
Folic acid's in an essential component of prenatal vitamins and is in many fortified foods such as cereals and pastas.
A diet lacking foods rich in folate or folic acid can lead to a folate deficiency.
Folic acid deficiency can also occur in people who have conditions, such as celiac disease, that prevent the small intestine from absorbing nutrients from foods (malabsorption syndromes).
Folic acid is important for a range of functions in the body.
Folic acid helps the body make healthy new red blood cells, for example. Red blood cells carry oxygen throughout the body. If the body does not make enough of these, a person can develop anemia, leading to fatigue, weakness, and a pale complexion.
Without enough folate, a person can also develop a type of anemia called folate deficiency anemia.
Folic acid is also important for the synthesis and repair of DNA and other genetic material, and it is necessary for cells to divide.
Folic acid is particularly important to get enough folate during pregnancy.
Folic acid deficiency during pregnancy can lead to neural tube irregularities, such as spina bifida and anencephaly.
Folic acid is a B vitamin.
Folic acid helps the body make healthy new cells. Everyone needs folic acid. For women who may get pregnant, it is really important. Getting enough folic acid before and during pregnancy can prevent major birth defects of her baby's brain or spine.
Foods with folic acid in them include
Leafy green vegetables
Dried beans, peas, and nuts
Enriched breads, cereals and other grain products
What is folic acid?
Folic acid is a type of B vitamin that is normally found in foods such as dried beans, peas, lentils, oranges, whole-wheat products, liver, asparagus, beets, broccoli, brussels sprouts, and spinach.
Folic acid helps your body produce and maintain new cells, and also helps prevent changes to DNA that may lead to cancer.
As a medication, folic acid is used to treat folic acid deficiency and certain types of anemia (lack of red blood cells) caused by folic acid deficiency.
Folic acid is sometimes used with other medications to treat pernicious anemia. Folic acid used alone will not treat pernicious anemia and other anemias not related to Vitamin B12 deficiency.
Folic acid is the natural form of vitamin B9, water-soluble and naturally found in many foods.
Folic acid is also added to foods and sold as a supplement in the form of folic acid; this form is actually better absorbed than that from food sources—85% vs. 50%, respectively.
Folic acid helps to form DNA and RNA and is involved in protein metabolism.
Folic acid plays a key role in breaking down homocysteine, an amino acid that can exert harmful effects in the body if it is present in high amounts.
Folic acid is also needed to produce healthy red blood cells and is critical during periods of rapid growth, such as during pregnancy and fetal development.
What is folic acid?
Folic acid is a synthetic, water-soluble vitamin used in supplements and fortified foods.
Folic acid’s a man-made version of folate, a naturally occurring B vitamin found in many foods. Your body can’t make folate, so it must be obtained through dietary intake.
Although the words folate and folic acid are often used interchangeably, these vitamins are distinct. Synthesized folic acid differs structurally from folate and has slightly different biological effects in the body. That said, both are considered to contribute to an adequate dietary intake.
Folic acid is found in a number of plant and animal foods, including spinach, kale, broccoli, avocado, citrus fruits, eggs, and beef liver.
Folic acid, on the other hand, is added to foods like flour, ready-to-eat breakfast cereals, and bread. Folic acid is also sold in concentrated form in dietary supplements.
Your body uses folate for a wide array of critical functions, including ;
the synthesis, repair, and methylation — the addition of a methyl group — of DNA
the conversion of homocysteine to methionine, an amino acid that’s used for protein synthesis or converted into S-adenosylmethionine (SAMe), a compound that acts as a primary methyl donor in your body and is necessary for numerous cellular reactions
the maturation of red blood cells
Folic acid is involved in a number of vital metabolic processes, and deficiency leads to an array of negative health outcomes, including megaloblastic anemia, increased risk of heart disease and certain cancers, and birth defects in infants whose mothers were deficient in folate.
Folic acid deficiency has multiple causes, including:
poor dietary intake
diseases or surgeries that affect folate absorption in the digestive system, including celiac disease, gastric bypass, and short bowel syndrome
achlorhydria or hypochlorhydria (absent or low stomach acid)
drugs that affect folate absorption, including methotrexate and sulfasalazine
Many countries, including the United States, require grain products to be fortified with folic acid to reduce the incidence of folate deficiency.
This is because folate deficiency is somewhat common, and some populations, including older adults and pregnant women, find it difficult to obtain the recommended dietary intake through diet .
Benefits and uses
Both folic acid and folate are commonly used in supplemental form for a variety of reasons.
Although folic acid and folate supplements are typically used to treat the same conditions, they have different effects in the body and, therefore, may affect health in different ways, which will be explained later in this article.
What is folate or folic acid?
Folic acid is a B-group vitamin that is essential for good health, and is naturally present in many foods. A form of folate, called folic acid, is used in dietary supplements and added to foods to enrich them. These are known as fortified foods.
Why is folate important?
Our bodies need folate to make DNA and other genetic material.
Folic acid is also needed for the body’s cells to divide.
Folic acid is especially important in unborn babies because it helps the nervous system develop. In the very first weeks of pregnancy, the neural tube closes and fuses. The neural tube later becomes the baby’s brain and spinal cord.
What Is Folic Acid?
Folic acid (or folate) is a B vitamin (B9) found mostly in dark green vegetables like broccoli and spinach, legumes such as beans and peas, and enriched grains.
What is folic acid?
Folic acid is a vitamin that every cell in your body needs for healthy growth and development. If you take it before pregnancy and during early pregnancy, it can help protect your baby from birth defects of the brain and spine called neural tube defects. The neural tube is the part of a developing baby that becomes the brain and spinal cord. NTDs happen in the first month of pregnancy, before you may know that you’re pregnant. This is why it’s important to have enough folic acid in your body before you get pregnant.
What is folate/folic acid?
Folic acid is an essential B vitamin and is found naturally in leafy vegetables, citrus fruits, wholemeal bread, yeast, liver and legumes.
Folic acid refers to pteroylmonoglutamic acid and is the synthetic (‘man made’) form of folate.
Folic acid is used in dietary supplements and fortified foods and beverages.
Folic acid is more bio-available (more readily absorbed and used in the body) and stable, than naturally occurring food folate.
Why do we need folate?
Folic acid is important in cell growth and reproduction.
Folic acid deficiency can result in a type of anaemia called ‘megaloblastic anaemia’ which is a blood disorder characterised by the presence of enlarged immature and dysfunctional red blood cells (megablasts).
Folic acid is a form of folate (a B vitamin) that everyone needs. If you can get pregnant or are pregnant, folic acid is especially important.
Folic acid protects unborn babies against serious birth defects. You can get folic acid from vitamins and fortified foods, such as breads, pastas and cereals.
Folic acid is found naturally in foods such as leafy green vegetables, oranges, and beans.
Folic acid is the man-made form of folate, a B vitamin.
Folic acid is found naturally in certain fruits, vegetables, and nuts.
Folic acid is found in vitamins and fortified foods.
Folic acid and folate help the body make healthy new red blood cells. Red blood cells carry oxygen to all the parts of your body. If your body does not make enough red blood cells, you can develop anemia. Anemia happens when your blood cannot carry enough oxygen to your body, which makes you pale, tired, or weak. Also, if you do not get enough folic acid, you could develop a type of anemia called folate-deficiency anemia.
Folic acid, which is the inorganic form of folate, is one of the most commonly produced vitamins as a food supplement because it is not stored in the body and is lost during the preparation of foods. Vitamin B9, which plays a role in many biological processes in the body, is water-soluble.
Found in many foods, folate is most abundant in liver, organ meats, green leafy vegetables, yeast, grains and legumes.
Folic acid which can also be synthesized by microorganisms in the intestines, needs vitamin C to function in the body. The FDA and WHO (world health organization) recommend that women of childbearing age and pregnant women use folic acid supplements because of their increased requirements.
Folic acid is the synthetic form of B9, found in supplements and fortified foods, while folate occurs naturally in foods.
All the B vitamins are water-soluble, meaning the body does not store them.
Folic acid is crucial for proper brain function and plays an important role in mental and emotional health.
Folic acid aids in the production of DNA and RNA, the body's genetic material, and is especially important when cells and tissues are growing rapidly, such as in infancy, adolescence, and pregnancy.
Folic acid also works closely with vitamin B12 to help make red blood cells and help iron work properly in the body.
What is folic acid?
Folic acid is the man-made (synthetic) form of folate, a B vitamin that is important for the formation of red blood cells and producing and maintaining new cells in your body. Most people get enough folate naturally from a healthy, balanced diet. However for some people, folate from the diet is not enough and folic acid tablets are needed.
Folic acid is used by pregnant women or women who are planning a pregnancy, to decrease the chance of spina bifida and other neural tube defects in the baby.
Folic acid is best to start taking folic acid before conception and continue until week 12 of pregnancy. If the pregnancy is unplanned, start taking folic acid as soon as you know you are pregnant.
For anaemia: Folic acid is used to treat or prevent some types of anaemia caused by folate deficiency by increasing the production of red blood cells.
To prevent side effects: For people who are taking methotrexate, folic acid is used to reduce some side effects caused by reduced folate, such as mouth ulcers.
What is folic acid?
Folic acid is one of the B vitamins your body needs for good health. Getting enough of this vitamin prevents folic acid deficiency anemia. It also prevents certain birth defects.
The vitamin is also called folate, but there is a difference:
Folate is the natural form of this vitamin. It's found in food.
Folic acid is the man-made form. It's put into vitamin pills and fortified foods, such as fortified breakfast cereals.
Folic acid-rich foods include: fortified breakfast cereals; enriched bread, rice, pasta and other grain products; orange juice; green vegetables; and legumes such as navy beans, kidney beans, lentils and garbanzo beans. A large glass of orange juice and a bowl of fortified cereal will provide 50-100% of the recommended daily amount of folic acid.
Folic acid is a crucial nutrient during pregnancy.
Folic acid helps prevent certain birth defects, and it contributes to the healthy growth of your placenta and baby.
Folic acid also helps prevent a type of anemia.
What is folic acid?
Folic acid is a form of vitamin B9, also known as folate. When the nutrient comes directly from food sources, it's called folate. When it's manufactured for use as a supplement or to fortify foods, it's called folic acid.
This vitamin helps prevent certain birth defects. Essential for the production, repair, and functioning of DNA – our genetic map and a basic building block of cells – it's crucial to the rapid cell growth of the placenta and your developing baby. Your body also needs folic acid to make normal red blood cells and prevent a type of anemia (folate-deficiency anemia).
Hill Formula C₁₉H₁₉N₇O₆
Molar Mass 441.4 g/mol
HS Code 2936 29 00
Melting Point 250 °C
pH value 4.0 - 4.8 (100 g/l, H₂O, 25 °C)
Bulk density 110 kg/m3
Solubility 0.002 g/l
Folic Acid is a collective term for pteroylglutamic acids and their oligoglutamic acid conjugates. As a natural water-soluble substance, folic acid is involved in carbon transfer reactions of amino acid metabolism, in addition to purine and pyrimidine synthesis, and is essential for hematopoiesis and red blood cell production.
Folic acid appears as odorless orange-yellow needles or platelets. Darkens and chars from approximately 482°F.
Folic acid is a water soluble vitamin found in many foods and particularly in leafy green vegetables that is essential for the critical biosynthetic pathways involving transfer of methyl groups to organic compounds. There is no evidence that folic acid, in physiologic or even super-physiologic, high doses, causes liver injury or jaundice.
Folic Acid is an important cofactor in the transfer of one-carbon moieties and plays big role in formation of S-adenosyl methionine and in the synthesis and repair of DNA and RNA.
Folic Acid depletion causes disruption of DNA integrity and repair enhancing carcinogenesis by altering expression of critical tumor suppressor genes.
Folic Acid is a substrate of DHFR.
Folic acid (folate) is a kind of B-vitamin which is mainly present in the liver and kidney. It has various kinds of pharmacological and physiological effects.
Folic Acid is involved in amino acid metabolism, purine and pyrimidine synthesis, and is also essential for hematopoiesis and red blood cell generation. In women pregnancy, folate can effectively prevent neural tube defects in the baby.
Folic Acid plays important role in fertility through contributing to spermatogenesis.
Folic Acid can also reduce the incidence of heart disease, stroke and cancer.
Folic Acid deficiency may lead to various kinds of diseases including glossitis, diarrhea, depression, confusion, anemia, and fetal neural tube defectsand brain defects (during pregnancy). Other symptoms may include fatigue, gray hair, mouth sores, poor growth, and swollen tongue.
Folic Acid is a water-soluble b-complex vitamin that aids in the for- mation of red blood cells, prevents certain anemias, and is essential in normal metabolism. high-temperature processing affects its sta- bility.
Folic Acid is best stored at lower than room temperatures.
Folic Acid is also termed folacin.
Folic Acid is found in liver, nuts, and green vegetables.
Folic Acid is generally used as an emollient. In vitro and in vivo skin studies now indicate its capacity to aid in DnA synthesis and repair, promote cellular turnover, reduce wrinkles, and promote skin firmness. There is some indication that folic acid may also protect DnA from uV-induced damage.
Folic acid is a member of the vitamin B complex and is naturally occurring in leafy greens.
Literature tends to indicate that B vitamins cannot pass through the layers of the skin and, therefore, are of no value in the skin surface. Current experiments demonstrate, however, that vitamin B2 acts as a chemical reaction accelerator, enhancing the performance of tyrosine derivatives in suntan-accelerating preparations.
Vitamin B9. A B-complex vitamin necessary for the body to produce red blood cells
Folic acid acts as a vitamin (hematopoietic), a nutritional supplement and dietary requirement for poultry.
Folic Acid also plays an important role in the formation of S-adenosyl methionine and in the synthesis and repair of DNA and RNA. Further, it serves as an essential vitamin for erythropoiesis.
Folic Acid is also employed in the treatment of methanol poisoning. In addition to this, it is used in the treatment and prevention of folate deficiencies and megaloblastic anemia.
Appearance (Colour) Orange yellow
Appearance (Form) Crystalline powder
Solubility (Turbidity) 10% solution in 1N NaOH Clear
Assay (UV) min. 98%
Loss on drying max. 10%
Sulphated Ash max. 0.1%
Absorbance (A) of 1% in 0.1N NaOH in a 1cm cell
@256nm 572 - 602
Spectral Ratio (A256nm/A365nm) 2.8 - 3.0
Widespread uses by professional workers
Folic acid is used in the following products: fertilisers.
Folic acid is used in the following areas: agriculture, forestry and fishing.
Other release to the environment of Folic acid is likely to occur from: indoor use as processing aid and outdoor use as processing aid.
Formulation or re-packing
Folic acid is used in the following products: fertilisers.
Release to the environment of Folic acid can occur from industrial use: formulation of mixtures and formulation in materials.
What is Folic Acid?
Folic acid enables the conversion of amino acids, which are the building blocks of protein structures, and is used in the growth and replication of DNA and nucleic acids.
One of the first systems your child's system at school is the nervous system, and folic acid is a role play of the education system. In the aforementioned period, neural tube defect (neural tube defect) is seen in the babies of pregnant women in folic acid facilities.
In spina bifida, the embryo of the tube that will form the brain and spinal cord does not close properly. Closure of the embryo's tube may be in the first nature of pregnancy.
Folic Acid Benefits
Folic acid is extremely important for its consistency as in the folic acid type.
Folic acid helps with the oxygen supply from the blood. With folic acid, fatigue, weakness and a moody complexion may develop.
Folic acid is also important for synthesizing, preparing and preparing DNA and other materials.
Folic acid can lead to neural tubules such as spin bifida and anencephaly especially in folic acid conditions.
Provides adequate protection against folic acid.
In Which Foods Is Folic Acid Found?
It is important to take folic acid tablets in the months before conception, especially if you are planning to have a baby. Using folic acid before pregnancy protects the baby against neural tube defects such as spina bifida in the future.
Some foods that contain folic acid are:
Parsley, mint, coriander
Folic acid is a synthetic form of vitamin B9, also known as pteroylmonoglutamic acid. Although terms are used interchangeably, it should be noted that folate and folic acid are two different types of vitamin B9.
Folic acid comes from the Latin word "folium". The word folium means green leaf.
Folic acid is the naturally occurring form of vitamin B9 in foods.
Folic acid is a synthetically produced folate derivative. The names are often used interchangeably, although there are distinct differences between the two. folate;
Folic acid is found in a wide variety of foods such as vegetables, legumes, cereals, eggs and fruit. Many foods are also fortified with synthetic folate or folic acid.
Folate taken into the body through nutrition is converted to its active form, 5-MTHF, before it enters the bloodstream. In the activation of folic acid, the liver and other tissues take part in addition to the digestive system.
What is folic acid?
Folic acid is a water-soluble vitamin that has many important functions in the body and is a synthetic form of folate.
Folic acid is found naturally in the content of many foods or in various supplements. Since it plays an important role in cell division, it is an extremely important vitamin to consume adequately during rapid growth periods such as pregnancy, infancy and adolescence.
What does folic acid do?
Folic acid plays a role in many different functions of the body.
Folic acid, which is involved in the synthesis of nitrogenous organic bases for the replication of DNA and RNA during cell division and the production of various cells, plays a key role especially in the maturation of red blood cells.
Folic acid deficiency can lead to the development of an anemia condition known as "macrocytic megaloblastic anemia" in both adults and children. Humans and other animals do not have the ability to synthesize folic acid. They can get the folic acid necessary for their bodies through foods and supplements.
What are the folic acid benefits?
The benefits of folic acid, the human-produced form of folate, can be listed as follows:
Folic acid has a reducing effect on the risk of preterm birth or congenital anomaly development. Folic acid is important to get enough folic acid during pregnancy to protect against miscarriage and neural tube defects.
Folic acid can reduce the risk of depression. Studies have shown that low folate level may be associated with an increased risk of depression and poor response to antidepressant treatment.
Folic acid helps maintain heart health.
Folic acid supplements have been shown to contribute to lowering homocysteine levels, which are associated with various heart conditions.
Because high homocysteine levels are associated with an increased risk of cardiovascular disease, some researchers think that folic acid and B12 reduce the risk of cardiovascular disease.
What Does Folic Acid Do?
This water-soluble vitamin has many functions in our body. Especially in case of folic acid deficiency during pregnancy, some congenital diseases are seen. The most common of these is the neural tube defect. The reason for this is that folic acid plays an important role in the development of the nervous system.
Folic acid is effective in the regeneration of cells in the body and the formation of new cells.
Folic acid has a function in the production of white and red blood cells in the bone marrow, in the production of DNA and RNA, in the conversion of carbohydrates into energy necessary for cells.
Folic acid also has an effect on preventing gene differentiation that may cause cancer.
Folic acid is known to prevent heart attacks and strokes by preventing arteriosclerosis. When folic acid is investigated in terms of side effects, no known side effects have been found so far. However, Folic acid is thought that folic acid, which is found in high amounts in the body, can hide vitamin B12 deficiency.
Folic acid (Folate-polisin, C19H19N7O6) is a vitamin from group B (B9).
Folic acid is given this name because it is commonly found in green leaves. Because in Latin, folum means leaf. Herschel K. Mitchell and colleagues discovered this vitamin in spinach leaves in 1941.
Folic acid is chemical name is pteroyl glutamic acid (PGA). Because it is composed of "pteridine", "PABA" and "glutamic acid". Also called the bc factor.
Folic acid is an orange-yellow solid that crystallizes in the shape of a lance in water, does not melt when heated, but decomposes by browning at 250 °C.
Folic acid is slightly soluble in free acid form, but very soluble in water as sodium salt.
Folic acid is not very resistant to heat in its basic and neutral solutions.
Folic acid works together with vitamin B12 in many places.
Folic acid plays an important role in cell division as it is necessary for DNA synthesis. In folic acid deficiency, cells cannot divide adequately.
Folic acid has a very important role in the development of the nervous system in the fetus.
Folic acid deficiency during pregnancy;
Folic acid can cause various congenital anomalies, especially neural tube defects such as spina bifida. Folic acid deficiency also;
Folic acid has been shown to be associated with depression, atherosclerosis and osteoporosis.
Folic acid is used as a supplementary vitamin, especially before and during pregnancy.
Folic acid has an important role in the formation of red blood cells and helps develop brain nerve tissues.
Folic acid, which has a vital value during pregnancy, must be taken for the healthy development of the baby and the health of the mother. Doctors recommend folic acid supplementation during pregnancy to prevent birth defects and strengthen the baby's development.
Folic acid is recommended that women take 400 micrograms of folic acid when they decide to become pregnant and continue this supplement until delivery.
Folic acid has been proven that many problems such as autism are caused by folate deficiency during pregnancy.
Folic acid was first separated from natural foods in some pharmacology laboratories in the United States in 1943-1944. Two years later, its chemical structure was shown.
Folic acid is involved in the production and proliferation of blood cells and the strengthening of the immune system.
Folic acid is a water-soluble vitamin that is usually found in foods of animal origin. Foods with the highest concentration are liver, organ meats, legumes, walnuts, almonds and green leafy vegetables. The bioavailability (rate of use by the body) of the form found in plants is low.
Folic acid, which is mostly found in green leafy vegetables, is a vitamin from group B. The use of this nutritional component, which creates positive developments in the course of many diseases, is very important during pregnancy.
Folic acid side effects do not cause serious symptoms. In some cases, it can hide a vitamin B12 deficiency. High levels of folic acid can increase bacterial growth in the gut.
Folic acid deficiency symptoms appear with indicators such as weakness and fatigue. The balanced use of this nutrient is important for the health of both you and your baby.
Using the right amount of folic acid during pregnancy prevents your baby's spinal cord and brain-centered birth defects, also known as neural tube defects.
You should take folic acid regularly to reduce the chance of problems such as brain damage, open spine (spina bifida) and mental development disorders.
You should regularly monitor your folic acid balance under the control of a physician.
You may need to use folic acid pills under the supervision of a physician during periods of need.
FOLIC ACID HYDRATE