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IODOPROPYNYL BUTYLCARBAMATE (IPBC)

IODOPROPYNYL BUTYLCARBAMATE (IPBC)

CAS NO 55406-53-6

EC NO   259-627-5

Iodopropynyl Butyl Carbamate (IPBC) is a water-soluble preservative used globally in the paints & coatings, wood preservatives, personal care, and cosmetics industries. IPBC is a member of the carbamate family of biocides. IPBC was invented in the 1970s and has a long history of effective use as an antifungal technology.

 


1-iodoprop-1-yn-3-yl n-n-butylcarbamate;3-iodo-2-propynyl butylcarbamate; 3-iodoprop-2-yn-1-yl butylcarbamate, carbamic acid, butyl-;3-iodo-2-propynyl ester; iodocarb; iodopropynyl butylcarbamate; ipbc;3-IODO-2-PROPYNYL BUTYLCARBAMATE, BUTYL-3-IODO-2-PROPYNYL ESTER CARBAMIC ACID, BUTYL-3-IODO-2-PROPYNYLCARBAMATE, BUTYLCARBAMIC ACID, 3-IODO-2-PROPYNYL ESTER, CARBAMIC ACID, BUTYL, 3IODO2PROPYNYL ESTER, CARBAMIC ACID, BUTYL-3-IODO-2-PROPYNYL ESTER, IDOPROPYNL BUTYLCARBAMATE, IODOPROPYL BUTYLCARBAMATE, IODOPROPYNL BUTYLCARBAMATE, IODOPROPYNYL BUTYLCARBAMATE, and IPBC
3-iodoprop-2-yn-1-yl butylcarbamate;Iodopropynyl butylcarbamate;Iodocarb;Ipbc;3-Iodo-2-propynyl butylcarbamate;1-Iodoprop-1-yn-3-yl N-n-butylcarbamate;Carbamic acid, butyl-, 3-iodo-2-propynyl ester;3-iodoprop-2-ynyl N-butylcarbamate;Butyl-3-iodo-2-propynylcarbamate;3-Iodo-2-propynyl butyl carbamate;3-Iodo-2-propynyl-N-butylcarbamate;3-iodoprop-2-ynyl butylcarbamate;Carbamic acid, N-butyl-, 3-iodo-2-propyn-1-yl ester;Carbamic acid, butyl-3-iodo-2-propynyl ester;iodocarbe;3-iodo-2-propynyl-N-butyl carbamate;3-Iodo-2-propynyl butylcarbamate #;IODOPROPYNYL BUTYL- CARBAMATE;3-iodo-2-propyn-1-yl N-butylcarbamate;3-iodoprop-2-yn-1-yl N-butylcarbamate;Iodocarb 100 microg/mL in Acetonitrile;3-Iodo-2-propynyl N-butylcarbamate, 97%;3-IODO-2-PROPYNYL BUTYL CARBBAMATE;N-Butylcarbamic Acid 3-Iodo-2-propynyl Ester;3-Iodo-2-propynyl N-butylcarbamate, analytical standard
3-iodo-2-propynyl-butylcarbamate;3-iodo-2-propynylbutylcarbamate;3-IPBC;iodopropynyl butylcarbamate;3-IODO-2-PROPYNYL BUTYLCARBAMATE;3-IODO-2-PROPYNYLBUTYLCARBAMATE;3-IODO-2-PROPYNYLBUTYLCARBAMATE [HSDB];3-IODO-2-PROPYNYL-N-BUTYL CARBAMATE;3-IODO-2-PROPYNYL-N-BUTYLCARBAMATE;3-IODOPROP-2-YNYL N-BUTYLCARBAMATE;IODOPROPYNYL BUTYL CARBAMATE [MART.];IODOPROPYNYL BUTYLCARBAMATE;IODOPROPYNYL BUTYLCARBAMATE [INCI];IODOPROPYNYL BUTYLCARBAMATE [VANDF];IPBC;IPBC [MI];3-Iodo-2-propynyl butyl carbamate, Biodocarb C 450, Butyl-3-iodo-2-propynylcarbamate, Carbamic acid,
butyl-3-iodo-2-propynyl ester, Lodopropynyl butylcarbamate;3-Iod-2-propin-1-yl-butylcarbamat;3-Iod-2-propin-1-yl-hydrogenbutylkohlenstoffimidat;3-Iodo-2-propyn-1-yl butylcarbamate;3-Iodo-2-propyn-1-yl hydrogen butylcarbonimidate;3-Iodo-2-propynyl butylcarbamate;3-Iodo-2-propynyl N-butylcarbamate;3-iodo-2-propynyl-butylcarbamate;3-Iodo-2-propynylbutylcarbamate;3-Iodo-2-propynyl-N-butylcarbamate;Butylcarbamate de 3-iodo-2-propyn-1-yle;Carbamic acid, N-butyl-, 3-iodo-2-propyn-1-yl ester;Hydrogénobutylcarbonimidate de 3-iodo-2-propyn-1-yle;Iodocarb;Iodopropynyl butylcarbamate;Ipbc;Methanol, 1-(butylimino)-1-[(3-iodo-2-propyn-1-yl)oxy]-, (Z)-;(ipbc)1-Iodoprop-1-yn-3-yl N-n-butylcarbamate;1-Phenyl-1,2-dihydroisoquinolin-3(4H)-one;3-iodo-2-propyn-1-yl N-butylcarbamate;3-iodo-2-propynyi butylcarbamate;3-Iodo-2-propynyl butyl carbamic acid;3-iodo-2-propynyl n-butylcarbamate 97%;3-iodo-2-propynyl n-butylcarbamate;3-iodo-2-propynyl n-butylcarbamate;3-iodo-2-propynyl??n-butylcarbamate;3-Iodo-2-propynylbutyl carbamate;3-iodoprop-2-yn-1-yl N-butylcarbamate;3-iodoprop-2-ynyl butylcarbamate;3-iodoprop-2-ynyl N-butylcarbamate;3-Iodopropynyl butylcarbamate;3-IPBC;Butyl-3-iodo-2-propynylcarbamate;Carbamic acid, butyl-, 3-iodo-2-propynyl ester;carbamic acid, butyl-, 3-iodoprop-2-ynyl ester;Carbamic acid, butyl-3-iodo-2-propynyl ester;Iodocarb (IPBC);iodocarbe;iodopropynyl butylcarbamate;Iodopropynylbutylcarbamate;N-[2-(1-iodoethyl)pent-3-enyl]carbamate;N-butyl(3-iodoprop-2-ynyloxy)carboxamide;N-butylcarbamic acid 3-iodoprop-2-ynyl ester;IBP;IPBC;woodlife;PERMATOX;Glycacil;IODOCARB;asc 67000;Kitazine P;Glycacil-L;Glycacil-S
Glycasil (trade name);Butyl-3-lodo-2-Propynylcarbamate;Carbamic Acid, Butyl-3-lodo-2-Propynyl Ester;IPBC;3-Iodo-2-propynyl butylcarbamate;3-iodo-2-propynyl;butyl-carbamicaci3-iodo-2-propynylester;Carbamicacid,butyl-,3-iodo-2-propynylester;ipbc(3-iodo-2-propynylnbutylcarbamate);troysankk-108a;troysanpolyphaseanti-mildew;woodlife;PERMATOX;Butyl-3-iodo-2-propynylcarbamate; Carbamic acid, butyl-3-iodo-2-propynyl ester; 3-Iodopropynylbutylcarbamate; 3-Iodo-2-propynyl butyl carbamate; 3-Iodo-2-propynyl-N-butyl carbamate IPBC; Carbamic acid, N-butyl-, 3-iodo-2-propyn-1-yl ester; 3-Iodo-2-propynyl butylcarbamate
iodocarb3-iodo-2-propynyl butylcarbamatebutyl-3-iodo-2-propynylcarbamateIodopropynyl butylcarbamate3-iodo-2-propyn-1-yl N-butylcarbamateIPBC3-iodoprop-2-ynyl butylcarbamate;Carbamicacid, butyl-, 3-iodo-2-propynyl ester (9CI);3-Iodo-2-propynylN-butylcarbamate;3-Iodo-2-propynyl butylcarbamate;3-Iodopropargyln-butylcarbamate;Acticide IPW 50;Biodocarb;Coatcide 123;Dekaben LMB;Ecobois;Fungitrol 720;Fungitrol 820;Fungitrol 920;Glycacil;Glycasil L;Guardsan 388;IBF 8DOP;IPBC;IPBC 40;Iodocarb;MP 100;Mergal 710S;Neomid220;Polyphase;Polyphase 641;Polyphase AF 1;Polyphase CST;Polyphase P100;Preventol MP 100;Thompson's Wood Protector;Troysan Polyphase AF 3;Troysan Polyphase P 100;Troysan Polyphase P 20T;Troysan Polyphase WD 17;Yotoru IP;1-İODOPROP-1-YN-3-YL N-N-BUTYLCARBAMATE;3-İODO-2-PROPYNYL BUTYLCARBAMATE; 3-İODOPROP-2-YN-1-YL BUTYLCARBAMATE, CARBAMİC ACİD, BUTYL-;3-İODO-2-PROPYNYL ESTER; İODOCARB; İODOPROPYNYL BUTYLCARBAMATE; İPBC;3-IODO-2-PROPYNYL BUTYLCARBAMATE, BUTYL-3-IODO-2-PROPYNYL ESTER CARBAMIC ACID, BUTYL-3-IODO-2-PROPYNYLCARBAMATE, BUTYLCARBAMIC ACID, 3-IODO-2-PROPYNYL ESTER, CARBAMIC ACID, BUTYL, 3IODO2PROPYNYL ESTER, CARBAMIC ACID, BUTYL-3-IODO-2-PROPYNYL ESTER, IDOPROPYNL BUTYLCARBAMATE, IODOPROPYL BUTYLCARBAMATE, IODOPROPYNL BUTYLCARBAMATE, IODOPROPYNYL BUTYLCARBAMATE, AND IPBC

3-İODOPROP-2-YN-1-YL BUTYLCARBAMATE;IODOPROPYNYL BUTYLCARBAMATE;IODOCARB;IPBC;3-IODO-2-PROPYNYL BUTYLCARBAMATE;1-IODOPROP-1-YN-3-YL N-N-BUTYLCARBAMATE;CARBAMİC ACİD, BUTYL-, 3-İODO-2-PROPYNYL ESTER;3-İODOPROP-2-YNYL N-BUTYLCARBAMATE;BUTYL-3-İODO-2-PROPYNYLCARBAMATE;3-IODO-2-PROPYNYL BUTYL CARBAMATE;3-IODO-2-PROPYNYL-N-BUTYLCARBAMATE;3-İODOPROP-2-YNYL BUTYLCARBAMATE;CARBAMİC ACİD, N-BUTYL-, 3-İODO-2-PROPYN-1-YL ESTER;CARBAMİC ACİD, BUTYL-3-İODO-2-PROPYNYL ESTER;İODOCARBE;3-İODO-2-PROPYNYL-N-BUTYL CARBAMATE;3-IODO-2-PROPYNYL BUTYLCARBAMATE #;IODOPROPYNYL BUTYL- CARBAMATE;3-İODO-2-PROPYN-1-YL N-BUTYLCARBAMATE;3-İODOPROP-2-YN-1-YL N-BUTYLCARBAMATE;IODOCARB 100 MİCROG/ML İN ACETONİTRİLE;3-IODO-2-PROPYNYL N-BUTYLCARBAMATE, 97%;3-IODO-2-PROPYNYL BUTYL CARBBAMATE;N-BUTYLCARBAMİC ACİD 3-IODO-2-PROPYNYL ESTER;3-IODO-2-PROPYNYL N-BUTYLCARBAMATE, ANALYTİCAL STANDARD;3-İODO-2-PROPYNYL-BUTYLCARBAMATE;3-İODO-2-PROPYNYLBUTYLCARBAMATE;3-IPBC;İODOPROPYNYL BUTYLCARBAMATE;3-IODO-2-PROPYNYL BUTYLCARBAMATE;3-IODO-2-PROPYNYLBUTYLCARBAMATE;3-IODO-2-PROPYNYLBUTYLCARBAMATE [HSDB];3-IODO-2-PROPYNYL-N-BUTYL CARBAMATE;3-IODO-2-PROPYNYL-N-BUTYLCARBAMATE;3-IODOPROP-2-YNYL N-BUTYLCARBAMATE;IODOPROPYNYL BUTYL CARBAMATE [MART.];IODOPROPYNYL BUTYLCARBAMATE;IODOPROPYNYL BUTYLCARBAMATE [INCI];IODOPROPYNYL BUTYLCARBAMATE [VANDF];IPBC;IPBC [MI];3-IODO-2-PROPYNYL BUTYL CARBAMATE, BİODOCARB C 450, BUTYL-3-İODO-2-PROPYNYLCARBAMATE, CARBAMİC ACİD,BUTYL-3-İODO-2-PROPYNYL ESTER, LODOPROPYNYL BUTYLCARBAMATE;3-IOD-2-PROPİN-1-YL-BUTYLCARBAMAT;3-IOD-2-PROPİN-1-YL-HYDROGENBUTYLKOHLENSTOFFİMİDAT;3-IODO-2-PROPYN-1-YL BUTYLCARBAMATE;3-IODO-2-PROPYN-1-YL HYDROGEN BUTYLCARBONİMİDATE;3-IODO-2-PROPYNYL BUTYLCARBAMATE;3-IODO-2-PROPYNYL N-BUTYLCARBAMATE;3-İODO-2-PROPYNYL-BUTYLCARBAMATE;3-IODO-2-PROPYNYLBUTYLCARBAMATE;3-IODO-2-PROPYNYL-N-BUTYLCARBAMATE;BUTYLCARBAMATE DE 3-İODO-2-PROPYN-1-YLE;CARBAMİC ACİD, N-BUTYL-, 3-İODO-2-PROPYN-1-YL ESTER;HYDROGÉNOBUTYLCARBONİMİDATE DE 3-İODO-2-PROPYN-1-YLE;IODOCARB;IODOPROPYNYL BUTYLCARBAMATE;IPBC;METHANOL, 1-(BUTYLİMİNO)-1-[(3-İODO-2-PROPYN-1-YL)OXY]-, (Z)-;(İPBC)1-IODOPROP-1-YN-3-YL N-N-BUTYLCARBAMATE;1-PHENYL-1,2-DİHYDROİSOQUİNOLİN-3(4H)-ONE;3-İODO-2-PROPYN-1-YL N-BUTYLCARBAMATE;3-İODO-2-PROPYNYİ BUTYLCARBAMATE;3-IODO-2-PROPYNYL BUTYL CARBAMİC ACİD;3-İODO-2-PROPYNYL N-BUTYLCARBAMATE 97%;3-İODO-2-PROPYNYL N-BUTYLCARBAMATE;3-İODO-2-PROPYNYL N-BUTYLCARBAMATE;3-İODO-2-PROPYNYL??N-BUTYLCARBAMATE;3-IODO-2-PROPYNYLBUTYL CARBAMATE;3-İODOPROP-2-YN-1-YL N-BUTYLCARBAMATE;3-İODOPROP-2-YNYL BUTYLCARBAMATE;3-İODOPROP-2-YNYL N-BUTYLCARBAMATE;3-IODOPROPYNYL BUTYLCARBAMATE;3-IPBC;BUTYL-3-İODO-2-PROPYNYLCARBAMATE;CARBAMİC ACİD, BUTYL-, 3-İODO-2-PROPYNYL ESTER;CARBAMİC ACİD, BUTYL-, 3-İODOPROP-2-YNYL ESTER;CARBAMİC ACİD, BUTYL-3-İODO-2-PROPYNYL ESTER;IODOCARB (IPBC);İODOCARBE;İODOPROPYNYL BUTYLCARBAMATE;IODOPROPYNYLBUTYLCARBAMATE;N-[2-(1-İODOETHYL)PENT-3-ENYL]CARBAMATE;N-BUTYL(3-İODOPROP-2-YNYLOXY)CARBOXAMİDE;N-BUTYLCARBAMİC ACİD 3-İODOPROP-2-YNYL ESTER;IBP;IPBC;WOODLİFE;PERMATOX;GLYCACİL;IODOCARB;ASC 67000;KİTAZİNE P;GLYCACİL-L;GLYCACİL-S

GLYCASİL (TRADE NAME);BUTYL-3-LODO-2-PROPYNYLCARBAMATE;CARBAMİC ACİD, BUTYL-3-LODO-2-PROPYNYL ESTER;IPBC;3-IODO-2-PROPYNYL BUTYLCARBAMATE;3-İODO-2-PROPYNYL;BUTYL-CARBAMİCACİ3-İODO-2-PROPYNYLESTER;CARBAMİCACİD,BUTYL-,3-İODO-2-PROPYNYLESTER;İPBC(3-İODO-2-PROPYNYLNBUTYLCARBAMATE);TROYSANKK-108A;TROYSANPOLYPHASEANTİ-MİLDEW;WOODLİFE;PERMATOX;BUTYL-3-İODO-2-PROPYNYLCARBAMATE; CARBAMİC ACİD, BUTYL-3-İODO-2-PROPYNYL ESTER; 3-IODOPROPYNYLBUTYLCARBAMATE; 3-IODO-2-PROPYNYL BUTYL CARBAMATE; 3-IODO-2-PROPYNYL-N-BUTYL CARBAMATE IPBC; CARBAMİC ACİD, N-BUTYL-, 3-İODO-2-PROPYN-1-YL ESTER; 3-IODO-2-PROPYNYL BUTYLCARBAMATE İODOCARB3-İODO-2-PROPYNYL BUTYLCARBAMATEBUTYL-3-İODO-2-PROPYNYLCARBAMATEIODOPROPYNYL BUTYLCARBAMATE3-İODO-2-PROPYN-1-YL N-BUTYLCARBAMATEIPBC3-İODOPROP-2-YNYL BUTYLCARBAMATE;CARBAMİCACİD, BUTYL-, 3-İODO-2-PROPYNYL ESTER (9CI);3-IODO-2-PROPYNYLN-BUTYLCARBAMATE;3-IODO-2-PROPYNYL BUTYLCARBAMATE;3-IODOPROPARGYLN-BUTYLCARBAMATE;ACTİCİDE IPW 50;BİODOCARB;COATCİDE 123;DEKABEN LMB;ECOBOİS;FUNGİTROL 720;FUNGİTROL 820;FUNGİTROL 920;GLYCACİL;GLYCASİL L;GUARDSAN 388;IBF 8DOP;IPBC;IPBC 40;IODOCARB;MP 100;

Iodopropynyl Butyl Carbamate (IPBC) is a water-soluble preservative used globally in the paints & coatings, wood preservatives, personal care, and cosmetics industries. IPBC is a member of the carbamate family of biocides. IPBC was invented in the 1970s and has a long history of effective use as an antifungal technology.IPBC is an effective fungicide at very low concentrations in cosmetic and other products, and has shown very low sensitivity in humans tested with this preservative. IPBC was approved in 1996 for use up to 0.1% concentrations in topical products and cosmetics. However, this preservative is mostly found in cosmetics at about one-eighth that level [Maier et al., 2009]. IPBC Toxicity and Safety Tests show it to be generally safe: When used properly in leave-on skin products, IPBC is extremely safe [Steinberg, 2002]. Previous to being approved for cosmetic use in 1996, extensive safety and toxicity tests were conducted on IPBC and their results were gathered along with earlier studies in a report of the Safety Assessment of IPBC by the Cosmetic Ingredient Review.. This final report found IPBC to be a non-carcinogen with no genotoxicity and in reproductive and developmental toxicity studies using rats and mice, IPBC had no significant effect on fertility, reproductive performance, or on the incidence of fetal malformation.The study, "Final Report on the Safety Assessment of Iodopropynyl Butylcarbamate", discusses the results of 32 studies between 1990 and 1994 in 3,582 subjects using skin application of IPBC at relevant concentrations. All 32 studies showed no evidence of contact sensitization compared to placebo controls, with the report stating "With each test formulation, a few panelists had erythema, edema, and/or a papular response, but overall, the results were negative." In addition, the study mentions two skin sensitivity studies on 183 children ages 3 – 12 yrs which showed no adverse effects as well as no significant irritation from IPBC. Since the early safety report, there have been a few reports of human skin sensitivity to IPBC in individual patients – all of which showed complete recovery after discontinuance of use of any product containing the IPBC which was presumably an allergen for these patients. Post-1996 tests of human sensitivity to IPBC have all shown quite low sensitivity, having overall reported human skin testing (patch test) on 53,774 subjects with only 491 of those subjects showing any reaction (0.8%) to IPBC. In every study, positive patch test reactions occurred in less than 1% of subjects tested in all but one study. This is a very low reaction rate, but it is not zero, and the industry reports this low rate of reaction even though in the largest study of 25,435 subjects over 69% of the reactions were either weak or doubtful .These combined studies showing prevalence of reaction below 1% means that IPBC at this time does not have the reaction rates necessary to be included as an allergen in standard allergy series. But, it remains under close monitoring as it is a relatively new preservative for cosmetic products and will presumably increase in usage. Most human patch tests performed before 2004 were with 0.1% IPBC solutions, i.e. 10 times the concentration used in many cosmetic products. Some used 0.5% IPBC. In 2004, it was suggested that a better concentration for tests of this substance would be 0.2%. and this has contributed to the diagnosis of more sensitizations to this substanceOne study showed significantly increased sensitivity between 2005 and 2010 using 0.5% IPBC in patch tests.Iodopropynyl Butylcarbamate, also known as IPBC, is a white or slightly off-white crystalline powder that contains iodine. It is used in a wide variety of cosmetics and personal-care products.Iodopropynyl Butylcarbamate prevents or retards bacterial growth, thereby protecting cosmetics and personal-care products from spoilage.It is an effective bactericidal preservative, mainly used in cosmetics, household chemicals, paint, leather, plastic, wood, metal cutting fluid, wood color control, textiles, paper industry, ink, adhesives, etc. It is non-irritating at a concentration of ≤ 0.1% and is a new anti-dandruff anti-itching agent.IPBC is a preservative that helps prevent mold, bacteria, and other germs from spreading in creams, lotions, and other products. It was used for years in paints, primers, and coolants, and only more recently in cosmetic products, as it is effective against a wide variety of microorganisms. You're likely to find it in foundations, concealers, bronzers, self-tanners, eye shadows, mascaras, makeup removers, shampoos, conditioners, shaving creams, diaper creams, anti-itch and rash creams, bath soaks, body washes, hair dyes, lip balms, and moisturizers.Iodopropynyl butylcarbamate or IPBC is a preservative used in wet wipes, paint, primers, coating and cosmetics to prevent bacteria and fungi’s in the products. It has been approved by the FDA for use as a component of adhesive that may safely be used in articles intended for use in packing and holding food. IPBC was developed in the 1970´s for industrial use in the wood industry as a preservative for paint and coating and in 1996 it was approved for cosmetics. In the EU, IPBC is not allowed in leave on products to small children (≤3 years).Iodopropynyl butylcarbamate (IPBC) is a highly effective fungicide and bactericide. It is used as a preservative for wood and paints as well as in cosmetic formulations and various consumer products. Further research may identify additional product or industrial usages of this chemical.Iodopropynyl Butylcarbamate is a compound used as a fungicide and bactericide for wood and paint preservation and now also permitted and used as a cosmetics preservative.Iodopropynyl butylcarbamate (IPBC) is an internationally recognized chemical that has been used for years because of its wide field of application. Initially used as a water-based paint and wood preservative and then in metalworking fluids, its role has expanded into the more recent uses in cosmetic products. The need for a potent, broad-spectrum, and safe preservative system in cosmetics allowed for the discovery of several combinations of IPBC effective against a wide variety of organisms. Although IPBC has claimed to be safe when used at concentrations less than 0.1%, the introduction of IPBC into cosmetics has led to several reports labeling IPBC as a potential new contact allergen. As the use of this seemingly safe preservative becomes vast, an increased number of cases of IPBC-induced contact allergy is likely.Iodopropynyl butylcarbamate (IPBC) is a broad‐spectrum preservative for use in several product types, including cosmetics, in which its concentrations have been limited by EU legislation because of concerns related to its iodine content and release, and the risk of subsequent iodine overdose.Iodopropynyl butylcarbamate, in the shorter form known as IPBC, is a biocide from carbamate family. It comes as white or slightly off-white powder, with iodine in it.In the case of IPBC, the co-crystals can be formed by a supramolecular approach involving the assembly of IPBC with selected chemical species called co-crystal formers, which are able to establish non-covalent interactions involving the iodine atom (halogen bond, XB) present in the molecular structure of IPBC. The co-crystal formers used in the invention are: organic bases, in particular aliphatic amines or aromatic heterocyclic derivatives containing at least one basic nitrogen atom; halides; phosphates; and carboxylates. Independently to the method used, the obtained co-crystals have different physical and chemical properties compared to the original compound, without altering the biological activity of the active pharmaceutical ingredient. The co-crystals are more performing than the pure IPBC molecule even when used to prepare formulations such as solutions, emulsions, suspensions, powders, foams, pastes, granules, tablets and inhalers, or microencapsulated in polymers.Iodopropynyl butylcarbamate (IPBC) is an internationally recognized chemical that has been used for years because of its wide field of application. Initially used as a water-based paint and wood preservative and then in metalworking fluids, its role has expanded into the more recent uses in cosmetic products. The need for a potent, broad-spectrum, and safe preservative system in cosmetics allowed for the discovery of several combinations of IPBC effective against a wide variety of organisms. Although IPBC has claimed to be safe when used at concentrations less than 0.1%, the introduction of IPBC into cosmetics has led to several reports labeling IPBC as a potential new contact allergen. As the use of this seemingly safe preservative becomes vast, an increased number of cases of IPBC-induced contact allergy is likely.Iodopropynyl butylcarbamate is a preservative that can also be found in skin creams and shampoos. It helps maintain product quality and performance over time. Some people raise concerns about preservatives, because a small number of individuals have allergies to them just as some people have allergies to nuts or bees. But preservatives play a very important role in food, cosmetics and household products. Without preservatives, many products would not last more than a week or two before being contaminated by bacteria, mold or yeast. So, we feel the best choice is to add preservatives in the smallest effective quantity to protect our products, but to list these preservatives in our formulas so that those with allergies in the family can make informed choices.

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