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CAS number: 85736-63-6
Nipacide BNPD is an in-can biocide based on Bronopol.
Nipacide BNPD is recommended for preservation of a wide range of applications including Paints, varnishes, adhesives, emulsions (polymers), slurries, metal working fluids and home care products where the protection against bacteria and fungi is required in humid state (in can protection).
Nipacide BNPD is especially effective against bacteria including Pseudomonas sp. and sulphate reducing bacteria (SRB).
Nipacide BNPD is a broad spectrum antimicrobial agent designed for preservation of a wide range of cosmetics and toiletries.
Nipacide BNPD is suitable for both rinse-off and leave-on formulations.
Nipacide BNPD is effective against bacteria, fungi, and yeast.
Bromo-nitropropanediol.
Low toxicity biocide.
Effective against bacteria, fungi and yeast.
Specifically developed for the complete microbiological protection of water-based products against bacterial and fungal spoilage in the wet state.
Nipacide BNPD is an in-can biocide based on Bronopol.
Nipacide BNPD is an aqueous solution recommended for preservation of a wide range of applications including Paints, varnishes, adhesives, emulsions polymers , slurries, metal working fluids and home care products where the protection against bacteria and fungi is required in humid state in can protection.
Nipacide BNPD is especially effective against bacteria including Pseudomonas sp. and sulphate reducing bacteria SRB.
Nipacide BNPD is bromo-nitropropanediol.
Nipacide BNPD is a low toxicity biocide developed for the in-can protection of water based products.
Nipacide BNPD is effective against a wide range of bacteria but has limited activity against yeast and fungi.
Microorganisms grow at a rapid rate and without use of the correct biocide, numbers can increase dramatically.
Example of the numbers of bacteria able to grow in products if left unpreserved:
Time = 0 mins 1
Time = 40 mins 4
Time = 3 hrs 1024
Time = 5 hrs 16,384
Time = 7 hrs 1,048,576
Time = 10 hrs 107,000,000,000
Time = 24 hrs 236,000,000,000,000,000,000,000
Available microbiological testing of Nipacide BNPD:
In can challenge.
Dry film
Chemical analysis
Identification
Disinfectant testing
Microbiological audits
Characteristics of Nipacide BNPD:
Praepagen HY could be classified as a typical cationic surfactant whose solubility or hydrophilic characteristics are improved by the presence of a hydroxyl group in Nipacide BNPD structure.
This characteristic makes possible Nipacide BNPD’s use in typical anionic formulations, and shows particular benefits of synergistic action on removal of difficult stains like oily and fatty ones from fabrics or other surfaces, even after ageing.
Praepagen HY presents a synergistic effect when incorporated with anionic, amphoteric and/or non-ionic surfactants.
Chemical compatibility;
Nipacide BNPD is compatible with most raw materials used in the manufacture of industrial products.
Care should be taken when using Nipacide BNPD in formulations containing amines.
Nipacide BNPD compatibility should always be checked and evaluated before use.
Applications of Nipacide BNPD:
Emulsion polymerization
Pigment preparation
Waterborne paints
Decorative paints
In-can preservation
Nipacide BNPD is recommended for preservation of a wide range of applications including water based, latex and PVA adhesives.
Polymer emulsions including, Polyvinyl acetate and acrylic.
Water based decorative paints, household products including dishwashing liquids, printing inks and fountain solutions.
Nipacide BNPD is particularly effective when additional antibacterial activity is required.
Nipacide BNPD is effective over a pH range of 4 to pH 8 and at temperature below 40 C.
Use of Praepagen HY in laundry powder detergents:
Praepagen HY is a detergency booster for use in all laundry detergent powders and liquids for clothes washing in household, industrial and institutional areas.
Praepagen HY can be added in the slurry stage or can be adsorbed in zeolite, layered silicate or other inorganic material for post-dosage.
Praepagen HY is recommended to be used at a dosage of 0.5 – 1.5% (active material) in the powder detergent formulation.
The washing tests were carried out with different soils (tomato sauce, raw palm oil, curry and chocolate) and different fabrics, 100% cotton and miscellaneous CO/PES (poplin, knitting, gabardine, sheet and tergal).
To reproduce difficult spots, one chose those frequently found in day-to-day soils, mainly the ones found in children’s clothes and kitchen towels.
The exact time of aging that the soil has in practice (the time the dirt remains in the fabric until Nipacide BNPD is washed) was also simulated.
The tests were carried out in three types of washing equipment: Linitest, Jar test modified and top loader washing machine – Brastemp.
Certain washing conditions, such as type and concentration of detergent, washing ratio, temperature and water hardness were found to affect the washing result.
In this work, the positive influence of Praepagen HY when added to HDP can be easily observed.
The results of spot removal were observed visually, which is important bearing in mind that this is the evaluation parameter used by the consumer, in final analysis when making his choise.
Use of Praepagen HY in hard surface cleaners:
Main characteristics:
Compatible in non-ionic and anionic liquid systems, even in the presence of builders.
Can be used as detergency booster.
Advantages:
Detergency increase in presence of anionic surfactants (including LAS).
Benefits observed in low concentration.
Disadvantages:
Relatively high cloud point.
Usage limited by LAS concentration (narrow compatibility range) and electrolytes.
In association with non-ionic surfactants no significant benefits have been observed.
Use of Praepagen HY in disinfectant cleaners:
Praepagen HY can be used in hard surface cleaners with an excess of cationic compounds, presenting all the benefits when compared to anionic cleaners but with a special anti-bacteria effect.
Microbiological tests – use Dilution Test
Methodology of Nipacide BNPD:
INCQS standard test for the anti-microbial activity of disinfectants:
"In vitro" test with stainless steel cylinders carriers.
The test is performed with 60 cylinders.
The disinfectant should be able to kill bacteria attached to 59 stainless steel cylinders in the contact time of 10 minutes for a 95% confidence limit.
Microorganism resistance of Nipacide BNPD:
To verify the strain resistance against a phenol solution 5.0% in the contact time of 5, 10 and 15 minutes
Results:
The hard surface cleaner test formulation tested was approved as a disinfectant agent.
Use of Praepagen HY in dishwashing detergents:
Main characteristics:
High water solubility.
Good compatibility with anionic, non-ionic and amphoteric surfactants.
High stability at low and high temperatures.
Good degreasing effect.
Advantages:
Detergency increase in presence of anionic surfactants (including LAS).
High viscosity increment using small quantity of electrolyte (NaCl).
Foam improvement, sometimes with stabilization effect.
Disadvantages:
Narrow compatibility range with LAS.
Can cause skin irritation when used in higher concentrations.
In-Can degradation in paints, polymer and adhesives as a result of bacterial and fungal contamination, can result in:
Loss of viscosity
Gassing
Discoloration
Bad odors
Product splitting
Loss of adhesion
Production clean down and production down time
Use level;
Nipacide BNPD should be evaluated as in finished products at levels between 0.02% and 0.05%.
Please note that Nipacide BNPD should be used in combination with other active biocides to provide full spectrum of antimicrobial activity to include yeasts and fungi
Storage of Nipacide BNPD:
Praepagen HY can be stored for at least to 2 years in original sealed containers at room temperature under the recommended conditions.
Protect from exposure to cold during transport and storage.
The properties of Praepagen HY are reversibly altered by exposure to cold.
If Praepagen HY becomes turbid, thickens or freezes through exposure to cold, thaw slowly at room temperature and afterwards stir briefly.
Benefits of Nipacide BNPD:
bactericide
fungicide
FDA approvals for various applications
Physical-chemical data of Nipacide BNPD:
Appearance: liquid
Concentration [%]: approx. 40
pH value (as is): 5.5 – 8.5
APHA color: max. 100 (Brazil, Mexico)
Chemical name: Alkyl hydroxyethyl dimethyl ammonium chloride
INCI name: Hydroxyethyl laurdimonium chloride
CAS number: 85736-63-6
Product Function: Industrial biocide
Chemical Type: Bronopol
NCI Name: 2-Bromo-2-Nitropropane-1,3-Diol
Regulations and approvals of Nipacide BNPD:
FDA21 CFR 175.105 Indirect food additives: Adhesive and components of coatings-Adhesives
FDA21 CFR 176.170 Indirect food additives: Paper and paperboard components-Components of paperboard in contact with aqueous and fatty foods
FDA21 CFR 176.180 Indirect food additives: Paper and paperboard components-Components of paper and paperboard in contact with dry food.
FDA 21 CFR.300 Indirect food additives: Paper and paperboard components-Slimicides.
BFR Rec X1V Preservative for Polymer emulsions in food contact applications.
WGK Classification 3: strongly water polluting
Technical Service of Nipacide BNPD:
Nipacide BNPD technical service staff is available to assist customers in the determination of the optimum use level of biocide required to fully protect their product.
A dedicated team of microbiologists are on hand at all time to assist customers with all technical inquiries relating to product protection.
Full microbiological efficacy testing is available.
Synonyms of Nipacide BNPD:
Nipacide BNPD
NIPACIDE BNPD
nipacide bnpd
NIPACIDEBNPD
NIPACIDE
BNPD
Bronopol
BRONOPOL
Nipacid BNPD
Nipasid BNPD
Nıpacıd BNPD
nipacidebnpd
NipacidBNPD
2-bromo-2-nitropropane-1,3-diol
1,3-Propanediol, 2-bromo-2-nitro-
2-BROM-2-NITRO-1,3-PROPANDIOL
2-BROMO-2-NITRO-, 1,3-PROPANDIOL
2-Bromo-2-nitro-1,3-propanediol
2-Bromo-2-nitropropan-1,3-diol
2-Bromo-2-nitropropane-1,3-diol
2-Nitro-2-bromo-1,3-propanediol
Acticide L 30
Bactrinol 100
BE 6
BE 6 (bactericide)
Bioban
BNPD
BNPK
Bronidiol
Bronocot
Bronopol
Bronotak
Canguard 409
Myacide AS
Myacide AS Plus
Myacide BT
Myacide Pharma BP
N 25
N 25 (antimicrobial)
Nalco 92RU093
NSC 141021
Onyxide 500
PROPANE-1,3-DIOL, 2-BROMO-2-NITRO-
Pyceze
Topcide 2520
Ultra Fresh SAB
UN 3241
β-Bromo-β-nitrotrimethyleneglycol
