PRODUCTS

SODIUM L-ASCORBATE

(VITAMIN C SODIUM SALT = L-ASCORBIC ACID SODIUM)

CAS Number: 134-03-2
Molecular Weight: 198.11
Empirical Formula (Hill Notation): C6H7NaO6
Beilstein: 3767246
EC Number: 205-126-1
MDL number: MFCD00082340
eCl@ss: 34058010
SMILES string: [Na+].OC[C@H](O)[C@H]1OC(=O)C(O)=C1[O-]
InChI:1S/C6H8O6.Na/c7-1-2(8)5-3(9)4(10)6(11)12-5;/h2,5,7-10H,1H2;/q;+1/p-1/t2-,5+;/m0./s1
InChI key: PPASLZSBLFJQEF-RXSVEWSESA-M
IUPAC Name: (2R)-2-[(1S)-1,2-dihydroxyethyl]-3,4-dihydroxy-2H-furan-5-one;molecular hydrogen;sodium

Sodium Ascorbate is a more bioavailable form of vitamin C that is an alternative to taking ascorbic acid as a supplement.
Sodium Ascorbate is a form of Vitamin C.
Sodium ascorbate is one of a number of mineral salts of ascorbic acid (vitamin C).
TAs the sodium salt of ascorbic acid, it is known as a mineral ascorbate.he molecular formula of this chemical compound is C6H7NaO6.
Sodium ascorbate normally provides 131 mg of sodium per 1,000 mg of ascorbic acid (1,000 mg of sodium ascorbate contains 889 mg of ascorbic acid and 111 mg of sodium).
Sodium ascorbate is ascorbic acid with a sodium molecule attached to help lessen its natural acidity.

Sodium Ascorbate is an ideal alternative to ascorbic acid if you find the pure form of vitamin C causes heartburn or other stomach upset.
Sodium L- Ascorbate is a buffered form of Vitamin C and as such, it is located in nature.
Sodium Ascorbate is a six carbon compound related to glucose.
Sodium Ascorbate is found naturally in citrus fruits and many vegetables.
L-Ascorbic acid sodium salt (Sodium L-ascorbate), an electron donor, is an endogenous antioxidant agent.
Sodium ascorbate is sodium salt of ascorbic acid (commonly known as vitamin C).

Sodium ascorbate consists of a combination of sodium and vitamin C, which commonly serve as an antioxidant and an acidity regulator in pharmaceutical manufacturing and in the food industry.
Sodium Ascorbate is a mineral salt of Ascorbic Acid [Vitamin C] (A786990), a physiological antioxidant.
L-Ascorbic acid sodium salt inhibits selectively Cav3.2 channels with an IC50 of 6.5 μM.
L-Ascorbic acid (Vitamin C) is a water soluble molecule use in a wide variety of applications, including cell culture, as a reducing agent that helps reduce oxidative stress.
Sodium Ascorbate is a weak base.
Sodium L-ascorbate is a white, small-grained crystalline powder used as a food additive to provide levels of vitamin C with reduced acidity and to extend the longevity of the color, aroma and nutrient content of the final product.

APPLICATIONS AND USES

(+)-Sodium L-ascorbate has been used:
as a component of cutting solution for storing brain slices of rats
as a component of patch pipette internal solution for imaging Ca2+ transients evoked by action potential in rat brain slices.
as a supplement for arterial smooth muscle cell (SMC) cultures to encourage collagen production

As a food additive, it has the E number E301 and is used as an antioxidant and an acidity regulator.
Sodium Ascorbate is approved for use as a food additive in the EU, USA, Australia, and New Zealand.
L-Ascorbic acid sodium salt is also a collagen deposition enhancer and an elastogenesis inhibitor.
L-Ascorbic acid sodium salt is used as an antioxidant, an acidity regulator and an antimicrobial in food stuff.
As a reductant, Sodium Ascorbate is involved in the isolation of chloroplasts.

Sodium Ascorbate acts as a coenzyme for many hydroxylation reactions.
Sodium Ascorbate plays a vital role to eliminate chronic and acute infections.
Sodium Ascorbate is a coenzyme for a number of hydroxylation reactions required for collagen synthesis.
Sodium Ascorbate is widely distributed in plants and animals.
Sodium Ascorbate is used as an antimicrobial and antioxidant in foodstuffs.
Sodium Ascorbate is soluble in water and provides a non acidic taste. a 10% aqueous solution has a ph of 7.3–7.6.

In water, Sodium Ascorbate readily reacts with atmospheric oxygen and other oxidizing agents, making it valuable as an antioxidant.
The resulting solutions of Sodium Ascorbate contain moderate concentrations of hydroxide ions and have pH greater than 7.0.
Sodium Ascorbate reacts as bases to neutralize acids.
Neutralizations like Sodium Ascorbate generate heat, but less or far less than is generated by neutralization of the bases in reactivity group 10 (Bases) and the neutralization of amines.
Sodium ascorbate is used as an antioxidant in pharmaceutical formulations, and also in food products where it increases the effectiveness of sodium nitrite against growth of Listeria monocytogenes in cooked meats.
Sodium Ascorbate improves gel cohesiveness and sensory firmness of fiberized products regardless of vacuum treatment.

Sodium Ascorbate is also used therapeutically as a source of vitamin C in tablets and parenteral preparations.
Sodium Ascorbate preserves nitric oxide (NO) which may help prevent endothelial dysfunction, helps prevent and reverse the oxidative damage done to proteins and lipids as a result of cigarette smoke.
cell culture
(+)-Sodium L-ascorbate has been used to produce H2O2 in cell culture media, as a reducing agent for a cell-permeable artificial electron donor, N,N,N′,N′-tetramethyl-p-phenylenediamine (TMPD), and to study its effect on production of collagen and elastic fibers in fibroblasts cultures derived from normal human skin and dermal fat.
Sodium Ascorbate is used for preparation of plant extracts; reductant for the isolation of chloroplasts.
(+)-Sodium L-ascorbate (SA) is a potential antioxidant and is a derivative of vitamin C (L-ascorbic acid).
In addition, Sodium Ascorbate enhances growth retardation activity of bleomycin sulfate, R020-1724 (an inhibitor of cyclic nucleotide phosphodiesterase), prostaglandin E1 and sodium butyrate agents on neuroblastoma cells in culture.

Sodium L-ascorbate in combination with collagenogenesis inhibitors is used to treat dermal scars and keloids.
Sodium Ascorbate is used in Miscellaneous, Household Chemicals, Food and Feed Additives.
Sodium Ascorbate is an antioxidants; free Radical Scavenger.
Ascorbic acid and calcium and sodium ascorbates are used as antioxidants in pharmaceutical manufacturing and in the food industry.
Sodium Ascorbate is used in food, beverage and dietary supplement applications as a Vitamin C source.
Some applications include chewable vitamins, processed meats, nutrient enhanced beverages and foods.
Sodium Ascorbate is used in dietary supplement applications including hard shell capsules and tablets.
Occasionally, Sodium Ascorbate is used for preservation of diagnostic medicinals.

Function:
to maintain the intercellular material;
A specific role in the synthesis of collagen, that is in the synthesis of the hydroxyproline or proline; In oxidation-reduction systems: glutathione, cytochrome C, pyridine or flavin nucleotides nucleoproteins; in the metabolism of adrenal steroids;
In the metabolism of various drugs.
Sodium Ascorbate increases the effectiveness of the immune system.
Sodium Ascorbate is an antioxidant, anti-aging material used in skin treatments, to boost collagen synthesis.

Sodium Ascorbate increases immune function
Sodium Ascorbate helps white blood cells function more effectively
Sodium Ascorbate protects against cough and common cold
Sodium Ascorbate improve iron absorption
Sodium Ascorbate can be used both as a nutrient (vitamin C) and as an additive (antioxidant).
Sodium ascorbate might be beneficial over ascorbic acid because it is buffered by the sodium, making it less acidic.

PHYSICAL AND CHEMICAL PROPERTIES

Sodium Ascorbate is white to almost white powder to crystal.
Sodium Ascorbate is freely soluble in water; very slightly soluble in ethanol.
Sodium ascorbate is relatively stable in air, although it gradually darkens on exposure to light.
Aqueous solutions are unstable and subject to rapid oxidation in air at pH > 6.0.
The bulk material should be stored in a well-closed nonmetallic container, protected from light, in a cool, dry place.

Specific rotation [a]20/D: +103 to +108 deg(C=10, H2O)
Solubility in Water: almost transparency
Melting Point: 218 °C
Specific Rotation: 105.5° (C=10,H2O)
Molecular Weight: 198.11
Hydrogen Bond Donor Count: 3
Hydrogen Bond Acceptor Count: 6
Rotatable Bond Count: 2
Exact Mass: 198.01403222
Monoisotopic Mass: 198.01403222
Topological Polar Surface Area: 110 Å²
Heavy Atom Count: 13
Formal Charge: 0
Complexity: 237
Isotope Atom Count: 0
Defined Atom Stereocenter Count: 0
Undefined Atom Stereocenter Count: 2
Defined Bond Stereocenter Count: 0
Undefined Bond Stereocenter Count: 0
Covalently-Bonded Unit Count: 2
Compound Is Canonicalize: Yes
Shipping: Room temperature in continental US; may vary elsewhere.
Storage: 4°C, protect from light
Appearance :Crystalline powder
Physical State :Solid
Solubility :Soluble in Water: 50 mg/mL
Storage :Store at room temperature
Melting Point :220° C
Turbidity 10% aq. solution: Clear
pH (10% aq. solution): 7.0 - 8.0
Specific rotation [α]:   +103 to +108° [C=10,water]
Loss on drying: max. 0.5%
Melting point: 220 °C (dec.)(lit.)
alpha: 104 º (c=1, H2O 25 ºC)
Boiling point: 235 °C
mp: 220 °C (dec.)
Density: 1.66
refractive index: 105.5 ° (C=10, H2O)
storage temp.: 2-8°C
solubility H2O: 50 mg/mL
form powder
color white to slightly yellow
PHpH (20g/l, 25℃) : 6.5～8.0
Odorodorless
optical activity[α]20/D: +105±2°, c = 5% in H2O
Water Solubility: 620 g/L (20 ºC)
Merck: 14,830
Storage: 0-4℃ for short term (days to weeks), or -20℃ for long term (months).
Description: White to light brownish powder
Assay: 99.0 - 101.0%
Specific optical rotation: +103° to +108°
pH of 10% solution: 7.0 – 8.0
Loss on drying at 60°C: Max. 0.25%
Heavy Metals (as Pb): Max. 0.002%
Melting Point [°C]: 200°C

Solubility in water: 62 g/100 ml at 250°C
A solution of the sample will decolourize a solution of 2,6-dichlorophenolindophenol TS.
Sodium Ascorbate is a microbial metabolite
Sodium Ascorbate has synthetic forms
L-Ascorbate can be regenerated by biological systems.

SYNONYMES

0134-03-02
L-ascorbic Acid Sodium Salt
(+)-Sodium L-ascorbate
11140_fluka
129940-98-3
156683-68-0
2,3-Didehydro-3-O-natrio-D-erythro-hexono-1,4-lacton
3-Hydroxy-4-(sodiooxy)-5-(1,2-dihydroxyethyl)furan-2(5H)-one
3-oxo-l-gulofuranolactone Sodium
50-81-7 (parent)
58657-35-5
73. 884311-57-3
7317-67-1
884311-57-3
A0539
A4034_sigma
A7631_sigma
A806721
Akos015895058
AKOS016373592
Aminofenitrooxon
Antiscorbutic vitamin
Ascorbate De Sodium
Ascorbato Sodico
Ascorbic Acid Sodium Derivative
Ascorbicin
Ascorbin
ASK-P 10KR
Bp-30077
C6h7o6.na
Cas-134-03-2
Ccris 3291
Cebitate
Cenolate; E 301
Cevitamic acid
Chembl591665
CK 40
CK 40 (ascorbate)
Dsstox_cid_105
Dsstox_gsid_20105
Dsstox_rid_75369
E 301 (Antioxidant)
E301
Einecs 205-126-1
FT-0627703
HBL 508
Hsdb 694
Iskia C
l-Ascorbate, sodium
L-ascorbic Acid, Monosodium Salt
L-ascorbic Acid, Sodium Salt (1:1)
L()-ascorbic Acid Sodium Salt
L(+)-Ascorbic acid sodium salt
Limcee
Ls-107459
Ls-2375
M609
MCULE-8774510897
Molport-003-925-923
Monosodium Ascorbate
Monosodium L-Ascorbate
natrascorb
Natri-C
Natrii Ascorbas
Ncgc00254355-01
Rp23764
S033eh8359
SCHEMBL19378674
Sodascorbate
sodium (2R)-2-(1,2-dihydroxyethyl)-4-hydroxy-5-oxo-2,5-dihydrofuran-3-olate
Sodium (2r)-2-[(1s)-1,2-bis(oxidanyl)ethyl]-4-oxidanyl-5-oxidanylidene-2h-furan-3-olate
Sodium (2r)-2-[(1s)-1,2-dihydroxyethyl]-4-hydroxy-5-oxo-2h-furan-3-olate
Sodium Ascorbate
Sodium Derivative Of 3-oxo-l-gulofuranolactone
Sodium Vitamin-c
Tox21_300556
Unii-s033eh8359
Vitamin C Sodium
Vitamin- C Sodium Salt