SODIUM PYRITHIONE

Sodium Pyrithione is the sodium salt form of pyrithione
Sodium Pyrithione is a fungistatic and antimicrobial derivative of aspergillic acid. 
Sodium Pyrithione is hygroscopic crystalline powder with a stench

CAS NUMBER: 15922-78-8

EC NUMBER: 240-062-8

MOLECULAR FORMULA: C5H4NNaOS

MOLECULAR WEIGHT: 149.15

IUPAC NAME: sodium;1-oxidopyridine-2-thione

Sodium Pyrithione is off-white solid
Sodium Pyrithione is formulated as liquid soluble concentrates

Sodium Pyrithione is mainly used for anti-mildew and antibacterial products in the fields of daily chemicals (shampoo and hair care products), architectural coatings, adhesives, sealants, pesticides, textiles, leather products, metal working fluids, etc. 
Sodium Pyrithione can also be formulated for disinfection agents, detergents and medical broad-spectrum antifungal dermatological products. 

At the same time, Sodium Pyrithione is also an effective fungicide
Sodium Pyrithione is an excellent common disinfectant for fruit trees, peanuts, wheat, vegetables and other crops. Its derivative product, zinc pyrithione

Sodium Pyrithione is also a commonly used fungicide for daily chemicals.
Sodium Pyrithione belongs to pyridine derivatives fungicide

Sodium Pyrithione's appearance is yellow full light dumpling transparent liquid
Sodium Pyrithione's melting point is 250℃

Sodium Pyrithione has slightly characteristic odor. 
Sodium Pyrithione is soluble in water and ethanol and other organic solvents

Sodium Pyrithione's solubility in water is 53%
Sodium Pyrithione is unstable to light, oxidizing agents and strong reducing agents. 

Non-ionic surfactants will deactivate it somewhat, and Sodium Pyrithione can chelate with heavy metals.
Sodium Pyrithione forms chelates with iron, manganese, zinc, etc.

USES:
Sodium Pyrithione is a preservative that is commonly used
Sodium Pyrithione is a bactericide for use in cooling fluids

Sodium Pyrithione is short-term in-can preservation of vinyl acetate latex, paints, and synthetic-fiber lubricants
Sodium Pyrithione is preservative for cosmetic rinse-off products.

Sodium Pyrithione is one of the active components in paint, sealants, shampoo, adhesive and aerosol due to its anti-microbial activity. 
In biochemistry studies, Sodium Pyrithione is utilized to transport zinc into cells. 

Further, Sodium Pyrithione is used to form bidentate oxothiolane chelates with transition metals. 
Sodium Pyrithione acts as a stabilizer and viscosity building provider in weak basic or neutral medium.

Sodium Pyrithione acts as labelling agent during indium-111 labelling of human platelets. 
Sodium Pyrithione acts as bioactive ligand

Sodium Pyrithione forms palladium and platinum complexes, which were tested as potential antitrypanosomal agents.
Sodium Pyrithione is a coordination complex of zinc.

Sodium Pyrithione has fungistatic (i.e. inhibits the division of fungal cells) and bacteriostatic (inhibits bacterial cell division) properties
Sodium Pyrithione is used to treat seborrheic dermatitis.

Sodium Pyrithione is chelated to Zn2+ via oxygen and sulfur centers.
In crystalline Sodium Pyrithione exists as a centripetal symmetrical dimer in which each zinc is bound to two sulfur and three oxygen centers.

However, in Sodium Pyrithione, in solution, dimers dissociate via cleavage of a Zn-O bond.
Sodium Pyrithione is the conjugate base derived from 2-mercaptopyridine-N-oxide, a pyridine-N-oxide derivative.
 
Sodium Pyrithione can be used to treat dandruff and seborrheic dermatitis.
Sodium Pyrithione has antibacterial properties

Effective against many pathogens from the Streptococcus and Staphylococcus genera
Sodium Pyrithione is used in the treatment of psoriasis and eczema.

Due to its low solubility in water (8 ppm at neutral pH), Sodium Pyrithione is suitable for use in outdoor paints and other products that protect against mold and algae.
Sodium Pyrithione is an effective algae inhibitor.

Sodium Pyrithione is chemically incompatible with paints based on metal carboxylate curing agents.
Sodium Pyrithione is slow to decompose by ultraviolet light

Sodium Pyrithione provides years of protection even against direct sunlight.
Sodium Pyrithione is used as an antibacterial treatment for household sponges.

APPLICATION AREAS:
-Shampoos

-Hair care products

-Laundry products

-Surface cleaning

-Pesticides

-Textile & leather industry

-Skin care products

-Cosmetic industry

-Household cleaning materials

-Medical Materials

Sodium Pyrithione is now used to prevent microbe growth in polyester.
Textiles treated with Sodium Pyrithione provide protection against odor-causing microorganisms.

Sodium Pyrithione is the sodium salt form of pyrithione, a fungistatic and antimicrobial derivative of aspergillic acid.
Sodium Pyrithione is also known as omadine sodium

Sodium Pyrithione is an organosulfur compound
Sodium Pyrithione's molecular formula is C5H4NNaOS. 

Sodium Pyrithione is the sodium salt form of pyrithione
Sodium Pyrithione is a fungistatic and antimicrobial derivative of aspergillic acid. 
Sodium Pyrithione is a broad spectrum antimicrobial, which inhibits the growth of bacteria and fungi in household and industrial products such as shampoos, hair care, laundry, surface cleaning, pesticides, and textile & leather treatment.

PHYSICAL PROPERTIES: 

-Molecular Weight: 149.15    

-Exact Mass: 148.99112921

-Monoisotopic Mass: 148.99112921    

-Topological Polar Surface Area: 58.4 Ų

-Physical Description: Hygroscopic crystalline powder with a stench

-Color: Off-White

-Form: Solid

-Vapor Pressure: 0.00000007 mmHg

-Melting Point: -25 °C

-Boiling Point: 109 °C

-Density: 1.22

-Refractive Index: 1.4825

-Storage Temperature: Hygroscopic, -20°C Freezer, Under inert atmosphere

-Solubility in Water: 0.1 M at 20 °C, clear, faintly yellow

-Water Solubility: 54.7 g/100 mL

-Sensitive: Hygroscopic

Sodium Pyrithione is used as a broad spectrum biocide especially against fungi and gram positive and gram negative bacteria in metal working fluids, rubber & paint, and cosmetics industries. 
At room temperature in the dark, Sodium Pyrithione is stable in the pH range 4.5 to 9.5. 

At 100°C Sodium Pyrithione is stable for at least 120 hours
At 150°C 29 % of the substance has decomposed within 48 hours.

CHEMICAL PROPERTIES: 

-Hydrogen Bond Donor Count: 0    

-Hydrogen Bond Acceptor Count: 2    

-Rotatable Bond Count: 0

-Heavy Atom Count: 9    

-Formal Charge: 0    

-Complexity: 166    

-Isotope Atom Count: 0    

-Defined Atom Stereocenter Count: 0    

-Undefined Atom Stereocenter Count: 0    

-Defined Bond Stereocenter Count: 0    

-Undefined Bond Stereocenter Count: 0    

-Covalently-Bonded Unit Count: 2    

-Compound Is Canonicalized: Yes

-Chemical Classes: Other Uses -> Biocides/Disinfectants

Sodium Pyrithione is off-white solid
Sodium Pyrithione is mainly used for anti-mildew and antibacterial products

Sodium Pyrithione is an excellent common disinfectant fo peanuts
Sodium Pyrithione is also a commonly used fungicide for daily chemicals.

Sodium Pyrithione belongs to pyridine derivatives fungicide
Sodium Pyrithione has slightly characteristic odor. 

Sodium Pyrithione is soluble in water and ethanol and other organic solvents
Sodium Pyrithione is a bactericide for use in cooling fluids

Sodium Pyrithione is preservative for cosmetic rinse-off products.
Sodium Pyrithione acts as a stabilizer and viscosity building provider in weak basic or neutral medium.

Sodium Pyrithione is a coordination complex of zinc.
Sodium Pyrithione is used to treat seborrheic dermatitis.

Sodium Pyrithione can be used to treat dandruff and seborrheic dermatitis.
Sodium Pyrithione has antibacterial properties

Sodium Pyrithione is used as an antibacterial treatment for household sponges.
Sodium Pyrithione is the sodium salt form of pyrithione, a fungistatic and antimicrobial derivative of aspergillic acid.

Sodium Pyrithione is also known as omadine sodium
Sodium Pyrithione is an organosulfur compound
Sodium Pyrithione is an antimicrobial derivative

SYNONYMS: 

Sodium Pyrithione
PYRITHIONE SODIUM
15922-78-8
Omadine sodium
Sodium Omadine
3811-73-2
Omacide 24
Pyrithione sodium
AL02725
sodium;1-oxidopyridine-2-thione
2(1H)-Pyridinethione, 1-hydroxy-, sodium salt
Sodium 2-thioxopyridin-1(2H)-olate
Tomicide s
1-Hydroxy-2(1H)-pyridinethione, sodium salt
Omadine-sodium
Caswell No. 790A
Pyrithione sodium (USAN)
Topcide 280
SODIUM SALT OF 1-HYDROXY 2(1H)-PYRIDINE THIONE
Sodium 2-sulfidopyridine 1-oxide
NSC-4483
Sodium 2-pyridinethiol-1-oxide
Sodium 1-hydroxypyridine-2-thione
AL-02725
EINECS 240-062-8
EPA Pesticide Chemical Code 088004
SQ 3277
1-Hydroxy-2(1H)-pyridinethionato sodium
Sodium omadine (TN)
Sel de sodium de 1-hydroxy-2 (1H)-pyridinethione [French]
Sodium Pyrithione 40% FPS
Sel de sodium de 1-hydroxy-2 (1H)-pyridinethione
SCHEMBL271923
CHEMBL2105351
DTXSID6034920
KKopsanop3380-34-5thione Na
2-mercaptopyridinen-oxidesodiumsalt
AKOS015891512
1-hydroxypyridine-2-thione sodium salt
FT-0612772
FT-0649466
D05662
1-?hydroxy-?2(1H)?-?Pyridinethione sodium salt
SODIUM OMADINE
2-MERCAPTOPYRIDINE-1-OXIDE SODIUM SALT
PYRITHIONE SODIUM
SODIUM-2-PYRIDINETHIOL-1-OXIDE
2-MERCAPTOPYRIDINE N-OXIDE SODIUM SALT
NaPT
Sodium pyrithion
UT900000
1-Hydroxy-2(1H)-pyridinethione sodium salt
1-HYDROXY-2-PYRIDINETHION SODIUM SALT
1-hydroxy-2-pyridinthione, sodium salt
2(1H)-Pyridinethione, 1-hydroxy-, sodium salt
2-(1H)-PYRIDINETHIONE, 1-HYDROXY-, SODIUM SALT
2-(1H)-Pyridinethione, 1-hydroxy-, sodium salt
2-Pyridinethiol, 1-oxide, sodium salt
2-Pyridinethiol-1-oxide, sodium salt
2-Pyridinethiol-1-oxide, sodium salt 
Piridin-2-thiol-1-oxide, sodium salt [inhalable fraction]
PYRIDINETHIOL [2(1H)], 1-HYDROXY-, SODIUM SALT
Pyrithione sodium
Sodium pyrithion, inhalable fraction
Sodium pyrithione
Sodium pyrithione (inhalable fraction)
SODIUM SALT OF 1-HYDROXY 2(1H)-PYRIDINE THIONE
Sodium salt of 1-hydroxy 2(1H)-pyridine thione
1-Hydroxy-2(1H)-pyridinethione Sodium Salt
2(1H)-Pyridinethione, 1-hydroxy-, sodium salt (1:1)
2-Thioxo-1(2H)-pyridinolate de sodium
Natrium-2-thioxo-1(2H)-pyridinolat
Sodium 2-thioxo-1(2H)-pyridinolate
Sodium 2-thioxopyridin-1(2H)-olate
Sodium omadine
Sodium pPyridinethione
(1-Hydroxy-2-pyridinethione), sodium salt
15922-78-8
1-Hydroxy-2(1H)-pyridinethionato sodium
1-HYDROXY-2-PYRIDINETHIONE SODIUM SALT
1-Hydroxy-2-pyridinethionesodiumsalt
1-OXIDE 2-PYRIDINETHIOL, SODIUM SALT
1-oxidopyridine-2-thione;sodium
2(1H)-Pyridinethione, 1-hydroxy-, sodium salt
2(1H)-Pyridinethione,1-hydroxy-, sodium salt (1:1)
223-296-5
240-062-8
2-Mercaptopyridine N-oxide sodium salt
2-Mercaptopyridine-N-oxide Sodium
2-Mercaptopyridine-N-oxide, sodium salt
3811-73-2 [RN]
5412-36-2 [RN]
6-thioxohydropyridin-1-ol, sodium salt
75164-71-5 [RN]
AGN-PC-00VDLB
AKOS002533568
AL02725
MFCD01941547 [MDL number]
n-hydroxy-2-pyridinethione sodium salt
Omacide 24
Omadine-sodium
pyridine-2-thione, 1-hydroxy-, sodium salt
Pyrithione
pyrithione sodium
PYRITHIONE SODIUM (INNM) (2)
pyrithione sodium salt
Sel de sodium de 1-hydroxy-2 (1H)-pyridinethione
Sodium (2-pyridylthio)-N-oxide
sodium 1-oxidopyridine-2-thione
SODIUM 2-SULFANYLIDENEPYRIDIN-1-OLATE
Sodium 2-sulfidopyridine 1-oxide
sodium and 1-oxidopyridine-2-thione
SODIUM PYRITHIONE
Sodium, (2-pyridinylthio)-, N-oxide
Sodium, (2-pyridylthio)-, N-oxide (7CI)
Sodium-2-pyridinethiol-1-oxide