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TETRASODIUM PHOSPHATE

CAS number : 7722-88-5
EC number : 231-767-1
Chemical formula: Na4O7P2

Tetrasodium Phosphate, also called sodium pyrophosphate or TSPP, is an inorganic compound with the formula Na4P2O7.
As a salt, Tetrasodium Phosphate is a white, water-soluble solid.
Tetrasodium Phosphate is composed of pyrophosphate anion and sodium ions.

Also known is the decahydrate Na4P2O7·10(H2O).
Tetrasodium Phosphate or TSPP is a solid white inorganic compound that is water soluble.
TSPP is a salt composed of pyrophosphate anions and sodium ions.
Tetrasodium Phosphate or TSPP is aproximately twice the toxicity level of common table salt.

Tetrasodium Phosphate or TSPP is most commonly produced by the reaction of phosphoric acid with sodium carbonate to form disodium phosphate, which is then heated to 450 °C to form Tetrasodium Phosphate.
Tetrasodium Phosphate or TSPP is primarily used as a food additive but also has a wide range of applications such as an emulsifier, thickening agent, buffering agent and dispersing agent.

Use:
Tetrasodium Phosphate is used as a buffering agent, an emulsifier, a dispersing agent, and a thickening agent, and is often used as a food additive.
Common foods containing Tetrasodium Phosphate include chicken nuggets, marshmallows, pudding, crab meat, imitation crab, canned tuna, and soy-based meat alternatives and cat foods and cat treats where Tetrasodium Phosphate is used as a palatability enhancer.

In toothpaste and dental floss, Tetrasodium Phosphate acts as a tartar control agent, serving to remove calcium and magnesium from saliva and thus preventing them from being deposited on teeth.
Tetrasodium Phosphate is used in commercial dental rinses before brushing to aid in plaque reduction.

Tetrasodium Phosphate is sometimes used in household detergents to prevent similar deposition on clothing, but due to its phosphate content Tetrasodium Phosphate causes eutrophication of water, promoting algae growth.
Tetrasodium Phosphate is used as a buffering agent, an emulsifier, a dispersing agent, and a thickening agent, and is often used as a food additive.

Tetrasodium Phosphate is widely used as an emulsifying salt (ES) in process cheese.
Common foods containing sodium pyrophosphate include chicken nuggets, marshmallows, pudding, crab meat, imitation crab, canned tuna, and soy-based meat alternatives and cat foods and cat treats where Tetrasodium Phosphate is used as a palatability enhancer.

Tetrasodium Phosphate is the active ingredient in Bakewell, the substitute for baking powder's acid component marketed during shortages in World War II.
Tetrasodium Phosphate is also used in some common baking powders.

Production
Tetrasodium Phosphate is produced by the reaction of furnace-grade phosphoric acid with sodium carbonate to form disodium phosphate, which is then heated to 450 °C to form Tetrasodium Phosphate: 2 Na2HPO4 → Na4P2O7 + H2O

Uses
Tetrasodium Phosphate is a coagulant, emulsifier, and sequestrant that is mildly alkaline, with a ph of 10.
Tetrasodium Phosphate is moderately soluble in water, with a solubility of 0.8 g/100 ml at 25°c.
Tetrasodium Phosphate is used as a coagulant in noncooked instant puddings to provide thicken- ing.
Tetrasodium Phosphate functions in cheese to reduce the meltability and fat separa- tion.
Tetrasodium Phosphate is used as a dispersant in malted milk and chocolate drink powders.
Tetrasodium Phosphate prevents crystal formation in tuna.
Tetrasodium Phosphate is also termed sodium pyrophosphate, tetrasodium diphosphate, and tspp.

Pharmaceutic aid.
Tetrasodium Phosphate (Na4P2O7) is a non-toxic and biocompatible compound used as an electroactive media for exfoliation of the surface coating.
Tetrasodium Phosphate is also be used as an additive in the food industry.
Na4P2O7 can be used as an inorganic additive to improve the stability and electrochemical performance of redox flow batteries.
As a water softener; as a metal cleaner; as a dispersing and emulsifying agent.

Tetrasodium Phosphate, also known as Sodium Pyro phosphate, Tetra sodium phosphate or TSPP, is achemical compound composed of pyrophosphate and sodium ions.

Application of Tetrasodium Phosphate:
• Tetra Sodium pyrophosphate is used as a buffering agent, also as an emulsifier and as a dispersing agent
• Tetrasodium Phosphate also used as a thickening agent and also often used as a food additive
• Tetrasodium Phosphate is used in common baking powders and also in toothpaste and dental floss as a tartar control
• Sometimes Tetrasodium Phosphate is also used in household detergents

Preparation of Tetrasodium Phosphate
Tetrasodium Phosphate is formed when pure disodium hydrogen orthophosphate is heated to 500℃ for 5 hours.
The product will contain better than 98 per cent Na4P2O7.
Crystalline masses large enough for optical measurements are produced by heating in platinum to above the melting point of the Tetrasodium Phosphate, 800°, and cooling slowly.
Higher temperatures or longer heating times do not change the Tetrasodium Phosphate, as this is the final product in the dehydration of disodium hydrogen orthophosphate.

Tetrasodium Phosphate is used as a cleaning compound; oil well drilling; water treatment, cheese emulsification; as a general sequestering agent, to remove rust stains; as am ingredient of one fluid ink eradicators, in electrodeposition of metals.
Tetrasodium Phosphate is used in textile dyeing; scouring of wool; buffer; food additive; detergent builder; water softener and dispersant.

Uses
Tetrasodium Phosphate is used as a pH buffer (a substance which maintains a particular acidity level), and as a dough conditioner in soy-based "meat alternatives".
Tetrasodium Phosphate promotes binding of proteins to water, binding the soy particles together, and is used for the same purpose in chicken nuggets and imitation crab and lobster products.
Tetrasodium Phosphate is an emulsifier, and a source of phosphorus as a nutrient.
Tetrasodium Phosphate is used in toothpastes, as a buffer, an emulsifier, and a detergent aid.
Tetrasodium Phosphate is the "tartar control" agent.
Tetrasodium Phosphate removes calcium and magnesium from the saliva, so they can't deposit on the teeth.
Tetrasodium Phosphate is a thickening agent in instant puddings.
Tetrasodium Phosphate is a water softener in detergents, and an emulsifier to suspend oils and prevent them from redepositing on clothing in the wash.
As a water softener, Tetrasodium Phosphate combines with magnesium to sequester Tetrasodium Phosphate from the detergent, without precipitating Tetrasodium Phosphate onto the clothing.
As a detergent additive, Tetrasodium Phosphate can also "reactivate" detergents or soaps that have combined with calcium to make an insoluble scum.
The TSPP sequesters the calcium, replacing Tetrasodium Phosphate with sodium, which reactivates the detergent or soap, and yet keeps the calcium from precipitating out of solution.
Because phosphates cause "eutrophication" of water (algae grows because of the fertilizing power of phosphates), Tetrasodium Phosphate is seldom used as a detergent additive, except in toothpastes.

Reactivity Profile
Tetrasodium Phosphate is basic.
Reacts exothermically with acids.
Incompatible with strong oxidizing agents.
Decomposes in ethyl alcohol.

Consumer Uses of Tetrasodium Phosphate:
Tetrasodium Phosphate is used in the following products: pH regulators and water treatment products, water softeners, cosmetics and personal care products, coating products and fillers, putties, plasters, modelling clay.
Release to the environment of Tetrasodium Phosphate can occur from industrial use: formulation of mixtures, in the production of articles and in processing aids at industrial sites.
Other release to the environment of Tetrasodium Phosphate is likely to occur from: indoor use (e.g. machine wash liquids/detergents, automotive care products, paints and coating or adhesives, fragrances and air fresheners) and outdoor use.

Service life of Tetrasodium Phosphate:
Release to the environment of Tetrasodium Phosphate can occur from industrial use: industrial abrasion processing with low release rate (e.g. cutting of textile, cutting, machining or grinding of metal).
Other release to the environment of Tetrasodium Phosphate is likely to occur from: outdoor use in long-life materials with low release rate (e.g. metal, wooden and plastic construction and building materials) and indoor use in long-life materials with low release rate (e.g. flooring, furniture, toys, construction materials, curtains, foot-wear, leather products, paper and cardboard products, electronic equipment).

Tetrasodium Phosphate can be found in products with material based on: stone, plaster, cement, glass or ceramic (e.g. dishes, pots/pans, food storage containers, construction and isolation material), fabrics, textiles and apparel (e.g. clothing, mattress, curtains or carpets, textile toys), leather (e.g. gloves, shoes, purses, furniture), paper (e.g. tissues, feminine hygiene products, nappies, books, magazines, wallpaper), wood (e.g. floors, furniture, toys) and plastic (e.g. food packaging and storage, toys, mobile phones).

Widespread uses by professional workers:
Tetrasodium Phosphate is used in the following products: pH regulators and water treatment products, water softeners and cosmetics and personal care products.
Tetrasodium Phosphate is used in the following areas: formulation of mixtures and/or re-packaging, agriculture, forestry and fishing, building & construction work and municipal supply (e.g. electricity, steam, gas, water) and sewage treatment.

Tetrasodium Phosphate is used for the manufacture of: metals, fabricated metal products and .
Release to the environment of Tetrasodium Phosphate can occur from industrial use: formulation of mixtures and in the production of articles.
Other release to the environment of Tetrasodium Phosphate is likely to occur from: indoor use (e.g. machine wash liquids/detergents, automotive care products, paints and coating or adhesives, fragrances and air fresheners) and outdoor use.

Formulation or re-packing of Tetrasodium Phosphate:
Tetrasodium Phosphate is used in the following products: pH regulators and water treatment products, water softeners and polymers.
Release to the environment of Tetrasodium Phosphate can occur from industrial use: formulation of mixtures, in the production of articles, in processing aids at industrial sites and as processing aid.

Other release to the environment of Tetrasodium Phosphate is likely to occur from: indoor use (e.g. machine wash liquids/detergents, automotive care products, paints and coating or adhesives, fragrances and air fresheners) and outdoor use.

Uses at industrial sites of Tetrasodium Phosphate:
Tetrasodium Phosphate is used in the following products: pH regulators and water treatment products, water softeners and polymers.
Tetrasodium Phosphate is used in the following areas: formulation of mixtures and/or re-packaging, mining and municipal supply (e.g. electricity, steam, gas, water) and sewage treatment.
Tetrasodium Phosphate is used for the manufacture of: chemicals, metals, fabricated metal products, machinery and vehicles.

Release to the environment of Tetrasodium Phosphate can occur from industrial use: in processing aids at industrial sites, formulation of mixtures, in the production of articles and as processing aid.
Other release to the environment of Tetrasodium Phosphate is likely to occur from: indoor use (e.g. machine wash liquids/detergents, automotive care products, paints and coating or adhesives, fragrances and air fresheners) and outdoor use.

Manufacture of Tetrasodium Phosphate:
Release to the environment of Tetrasodium Phosphate can occur from industrial use: manufacturing of the substance, formulation of mixtures, formulation in materials, in processing aids at industrial sites, in the production of articles and as an intermediate step in further manufacturing of another substance (use of intermediates).

Tetrasodium Phosphate is an inorganic sodium salt comprised of a diphosphate(4-) anion and four sodium(1+) cations.
Tetrasodium Phosphate finds much use in the food industry as an emulsifier and in dental hygiene as a calcium-chelating salt.
Tetrasodium Phosphate has a role as a food emulsifier, a chelator and a food thickening agent.

Molecular Weight: 265.90
Hydrogen Bond Donor Count: 0
Hydrogen Bond Acceptor Count: 7
Rotatable Bond Count: 0

Exact Mass: 265.87100346
Monoisotopic Mass: 265.87100346
Topological Polar Surface Area: 136 Å²
Heavy Atom Count: 13

Complexity: 124
Isotope Atom Count: 0
Defined Atom Stereocenter Count: 0
Undefined Atom Stereocenter Count: 0

Defined Bond Stereocenter Count: 0
Undefined Bond Stereocenter Count: 0
Covalently-Bonded Unit Count: 5
Compound Is Canonicalized: Yes

Tetrasodium Phosphate appears as odorless, white powder or granules. mp: 995 °C. Density: 2.53 g/cm3. Solubility in water: 3.16 g/100 mL (cold water); 40.26 g/100 mL boiling water.
Used as a wool de-fatting agent, in bleaching operations, as a food additive.
The related substance tetrasodium pyrophosphate decahydrate (Na4P2O7*10H2O) occurs as colorless transparent crystals.
Loses its water when heated to 93.8 °C

General description:
Tetrasodium Phosphate is a non-toxic and biocompatible compound used as an electroactive media for exfoliation of the surface coating.
Tetrasodium Phosphate is also be used as an additive in the food industry.

Application:
Tetrasodium Phosphate can be used as an inorganic additive to improve the stability and electrochemical performance of redox flow batteries.

Tetrasodium Phosphate, also called tetrasodium disphosphate or sodium pyrophosphate, is a synthetic ingredient that can be used as an acid regulator, sequestrant, protein modifier, coagulant, and a dispersing agent in food with the European food additive number E450(iii).
Tetrasodium Phosphate is gluten free and vegan.

How is Tetrasodium Phosphate made?
Tetrasodium Phosphate can be produced by the neutralization of phosphoric acid with sodium hydroxide with mol proportions of 2:1.

Food grade Tetrasodium Phosphate exists as two forms, and follows the corresponding chemical formula:
Tetrasodium Phosphate Anhydrous: Na4P2O7
Tetrasodium Phosphate Decahydrate: Na4P2O7 · 10H2O

An inorganic sodium salt comprised of a diphosphate(4−) anion and four sodium(1+) cations.
More commonly known as Tetrasodium Phosphate, Tetrasodium Phosphate finds much use in the food industry as an emulsifier and in dental hygiene as a calcium-chelating salt.

Tetrasodium Phosphate is bad for you, like most additives.
The additive has zero nutritional benefits and comes with many alarming side effects, especially when consumed in large quantities.
Tetrasodium Phosphate is a chemical compound formed by the reaction of phosphoric acid with sodium carbonate to create disodium phosphate which is then further heated to obtain the final product.
Let’s think about phosphoric acid for a minute.

Aside from Tetrasodium Phosphates use in making food additives, Tetrasodium Phosphate is otherwise mainly used to remove rust from metals.
Really? That doesn’t seem safe at all to be eating; can you imagine what Tetrasodium Phosphate would do to your insides?
In food, this additive is used as an emulsifier, thickener, dispersing agent, and as a pH buffering agent.

Tetrasodium Phosphate is typically found in highly processed foods like chicken nuggets, imitation crab, marshmallows, canned tuna, and soy-based meat alternatives – foods you shouldn’t eat much of anyway – if any at all.
The purpose of this ingredient in these foods Tetrasodium Phosphate to bind protein and water to keep all of the ground-up substances together.

Applications:
Tetrasodium Phosphate is used in water softener, detergent, emulsifying agent, metal cleaner and nutritional supplement.
Tetrasodium Phosphate acts as a buffering agent, thickening agent and dispersing agent.
Tetrasodium Phosphate also acts as a tartar control agent in toothpaste and dental floss.
In addition, Tetrasodium Phosphate is used as a chelating agent in antimicrobial studies.
Tetrasodium Phosphate is also used as a food additive in common foods such as chicken nuggets, crab meat and canned tuna.

What are the uses of
Tetrasodium Phosphate?
With the properties of chelating metal ions, increasing protein water holding capacity, PH buffering, stabilization, emulsification, casein thickening and ect, Tetrasodium Phosphate is widely used in food to improve the gel strength and the tenderness of meat products/analogs.
Also, Tetrasodium Phosphate is used with other phosphates (e.g. sodium hexametaphosphate, sodium acid pyrophosphate) in seafood to increase the water retention.

Food grade
Tetrasodium Phosphate is mainly used in following two functions:
A buffering agent: with the PH value from 9.8 to 10.8 (1% solution), Tetrasodium Phosphate can be used as an alkaline to adjust pH in processed food, pudding and etc.
A calcium sequestrant: TSPP can remove naturally occurring calcium ions from proteins and crosslink with proteins, which results in accelerating protein gelation, improving texture (mouthfeel) and reducing cooking loss in meat analog production (e.g. soy protein).

Following food list may contain
Tetrasodium Phosphate:
-Meat analogs, such as soy or wheat based food, with the appearance, flavor and mouth-feel the same with meat but not made from meat.
-Marshmallows
-Pudding
-Cheese
-Ice cream
-Milk protein products
-Tuna
-Toothpaste

Orally the main purpose of Tetrasodium Phosphate is to prevent the formation of calculus by reducing the deposition of calcium and magnesium on teeth.
Thus Tetrasodium Phosphate is commonly used as the anticalculus component of many tartar-control toothpastes and mouth rinse.
Disodium pyrophosphate also has the same function.
The top toothpaste manufacturer, Crest also uses Tetrasodium Phosphate as the anti-tartar ingredient in its whitening expressions.

Applications of Tetrasodium Phosphate has been shown to enhance the rate of pyrophosphate hydrolysis by nonenzymatic catlysis and by inorganic pyrophoshatase.
Pyrophosphoric Acid can be used for the preparation of vanadyl pyrophosphato methoxide cluster anion.
Pyrophosphoric Acid is used in anion binding of inorganic phosphates due to is ability to form complexes.

Where is Tetrasodium Phosphate found?
Sodium diphosphate is used as a food additive and thickening agent.
Tetrasodium Phosphate is found in chicken nuggets, marshmallows, pudding, crab meat, imitation crab, canned tuna, and soy-based meat alternatives, toothpaste, dental floss, and household detergents.

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Description
Tetrasodium Phosphate, also called Tetrasodium Phosphate or TSPP is used in the laboratory as a buffering agent.
Tetrasodium Phosphate has been shown to be useful in the preparation of an EDTA-sodium pyrophosphate extraction buffer for microcystin analysis of soil samples.
Tetrasodium Phosphate is an odorless, white powder or granules.
Tetrasodium Phosphate is used in water softener, buffering agent, thickening agent, dispersing agent, wool de-fatting agent, metal cleaner, soap and synthetic detergent builder, general sequestering agent, in electrodeposition of metals.

Tetrasodium Phosphate also acts as a tartar control agent in toothpaste and dental floss.
In addition, Tetrasodium Phosphate is used as a chelating agent in antimicrobial studies.
Tetrasodium Phosphate is also used as a food additive in common foods such as chicken nuggets, crab meat and canned tuna.

Tetrasodium Phosphate is generally immediately available in most volumes.
High purity, submicron and nanopowder forms may be considered.

Tetrasodium Phosphate is used as a dispersing agent, sequestrant, buffering agent, protein modifier, and coagulant.

Tetrasodium Phosphate is used to modify the proteins enabling them to retain moisture during storage, thawing, and cooking.
Tetrasodium Phosphate also increases shelf life of the product by sequestering multivalent cations responsible for lipid oxidation and rancidity development.
Tetrasodium Phosphate is added to improve whipping efficiency and improve foam stability.

Granular Tetrasodium Phosphate helps to buffer the pH of the processed cheese and interacts with milk proteins to promote emulsification.
Tetrasodium Phosphate sequesters iron in potato products to prevent after-cooking blackening and to stabilize color.
To maintain fat dispersion in an ice cream/dessert mix, TSPP may be added so "churning" will not form lumps of butter during freezing.

Mainly used in meat and seafood processing as a water retention agent, a stabilizer for natural pigments and to prevent fat corruption.
Tetrasodium Phosphate can also be used as a PH modifier, an emulsifier, a quality improver agent in dough and as a nutrient supplement.

Tetrasodium Phosphate also called TSPP is used as a buffering agent, emulsifier, dispersing agent, and a thickening agent in chicken nuggets, marshmallows, pudding, crab meat, imitation crab, canned tuna, and soy-based meat alternatives|and cat foods and cat treats|in dental hygiene products such as toothpaste, dental floss, commercial dental rinses and household detergents. CAS # (7722-88-5)

Primarily used as a food additive Tetrasodium Phosphate (TSPP) is a salt composed of pyrophosphate and sodium ions that possesses approximately twice the toxicity of table salt when ingested orally.
In general use, Tetrasodium Phosphate is used as an emulsifier, thickening agent, buffering agent, and a dispersing agent.

Chicken nuggets, crab meat, marshmallows, imitation crab, pudding, canned tuna, and numerous soy-based meat alternatives use TSPP, as do cat food and cat treat manufacturers to make their products more palatable to felines.
Tetrasodium Phosphate also functions as a tartar control agent in both dental floss and toothpaste by removing the calcium and magnesium found in saliva to prevent them from forming deposits on teeth.

Most Tetrasodium Phosphate is synthesized via the reaction of furnace-grade phosphoric acid and sodium carbonate in order to produce disodium phosphate, which is then heated to a temperature of 450 degrees C to form Tetrasodium Phosphate.
Another common method of synthesis is the molecular dehydration of dibasic sodium at 500 degrees C.

Another names:
Sodium pyrophosphate
TETRASODIUM PYROPHOSPHATE
7722-88-5
TSPP
Tetrasodium diphosphate
Phosphotex
Diphosphoric acid, tetrasodium salt
Sodium diphosphate
Victor TSPP
Caswell No. 847
Sodium pyrophosphate tetrabasic
Natrium pyrophosphat
Pyrophosphoric acid tetrasodium salt
Sodium diphosphate, anhydrous
Sodium phosphate (Na4P2O7)
HSDB 854
MFCD00003513
Na4P2O7
CHEBI:71240
O352864B8Z
Sodium pyrophosphate, tetrabasic
EINECS 231-767-1
NSC 56751
EPA Pesticide Chemical Code 076405
Sodium diphosphate tetrabasic
tetrasodium phosphonato phosphate
UNII-O352864B8Z
Tetrasodium pyrophosphate, anhydride
SODIUMPYROPHOSPHATE
tetra sodium pyrophosphate
EC 231-767-1
DSSTox_CID_22465
DSSTox_RID_80032
DSSTox_GSID_42465
Diphosphoric acid sodium salt
DTXSID9042465
Sodium diphosphate (Na4(P2O7))
Tetrasodium pyrophosphate Anhydrous
CS-B1771
Tox21_110033
AKOS015914004
AKOS024418778
Diphosphoric acid, sodium salt (1:4)
NCGC00013687-01
CAS-7722-88-5
FT-0689073D05873
E75941
Q418504
1004291-85-3