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TETRASODIUM PYROPHOSPHATE


EC / List no.: 231-767-1
CAS no.: 7722-88-5
Mol. formula: H4O7P2.4Na


Tetrasodium pyrophosphate, also called sodium pyrophosphate, tetrasodium phosphate or TSPP, is an inorganic compound with the formula Na4P2O7. 
As a salt, Tetrasodium pyrophosphate is a white, water-soluble solid. 
Tetrasodium Pyrophosphate is composed of pyrophosphate anion and sodium ions. 
Also known is the decahydrate Na4P2O7 · 10(H2O).

Uses of Tetrasodium pyrophosphate
Tetrasodium pyrophosphate is used as a buffering agent, an emulsifier, a dispersing agent, and a thickening agent, and is often used as a food additive. 
Common foods containing tetrasodium pyrophosphate include chicken nuggets, marshmallows, pudding, crab meat, imitation crab, canned tuna, and soy-based meat alternatives and cat foods and cat treats where Tetrasodium pyrophosphate is used as a palatability enhancer.

In toothpaste and dental floss, tetrasodium pyrophosphate acts as a tartar control agent, serving to remove calcium and magnesium from saliva and thus preventing them from being deposited on teeth. 
Tetrasodium pyrophosphate is used in commercial dental rinses before brushing to aid in plaque reduction.

Tetrasodium pyrophosphate is sometimes used in household detergents to prevent similar deposition on clothing, but due to Tetrasodium pyrophosphates phosphate content Tetrasodium pyrophosphate causes eutrophication of water, promoting algae growth.

Production of Tetrasodium pyrophosphate
Tetrasodium pyrophosphate is produced by the reaction of furnace-grade phosphoric acid with sodium carbonate to form disodium phosphate, which is then heated to 450 °C to form tetrasodium pyrophosphate:
2 Na2HPO4 → Na4P2O7 + H2O

Tetrasodium Pyrophosphate is a coagulant, emulsifier, and sequestrant that is mildly alkaline, with a ph of 10. 
Tetrasodium pyrophosphate is moderately soluble in water, with a solubility of 0.8 g/100 ml at 25°c. 
Tetrasodium Pyrophosphat is used as a coagulant in noncooked instant puddings to provide thicken- ing. 
Tetrasodium Pyrophosphat functions in cheese to reduce the meltability and fat separa- tion. 
Tetrasodium Pyrophosphat is used as a dispersant in malted milk and chocolate drink powders. it prevents crystal formation in tuna. 
Tetrasodium Pyrophosphat is also termed sodium pyrophosphate, tetrasodium diphosphate, and tspp.

Pharmaceutic aid of Tetrasodium pyrophosphate
Tetrasodium pyrophosphate (Na4P2O7) is a non-toxic and biocompatible compound used as an electroactive media for exfoliation of the surface coating. Tetrasodium Pyrophosphate is also be used as an additive in the food industry.
Na4P2O7 can be used as an inorganic additive to improve the stability and electrochemical performance of redox flow batteries.

As a water softener; as a metal cleaner; as a dispersing and emulsifying agent.

Preparation of Tetrasodium pyrophosphate    
Tetrasodium pyrophosphate is formed when pure disodium hydrogen orthophosphate is heated to 500℃ for 5 hours. 
The product will contain better than 98 per cent Na4P2O7. 
Crystalline masses large enough for optical measurements are produced by heating in platinum to above the melting point of the tetrasodium pyrophosphate, 800°, and cooling slowly. 
Higher temperatures or longer heating times do not change the tetrasodium pyrophosphate, as this is the final product in the dehydration of disodium hydrogen orthophosphate.

General Description of Tetrasodium pyrophosphate    
Odorless, white powder or granules. Mp: 995°C. Density: 2.53 g cm-3. Solubility in water: 3.16 g / 100 mL (cold water); 40.26 g / 100 mL boiling water. 
Used as a wool de-fatting agent, in bleaching operations, as a food additive. 
The related substance Tetrasodium pyrophosphate decahydrate (Na4P2O7 0H2O) occurs as colorless transparent crystals. 
Loses its water when heated to 93.8°C.

Tetrasodium pyrophosphate appears as odorless, white powder or granules. mp: 995°C. 
Density: 2.53 g/cm3. 
Solubility in water: 3.16 g/100 mL (cold water); 40.26 g/100 mL boiling water. 
Used as a wool de-fatting agent, in bleaching operations, as a food additive. 
The related substance tetrasodium pyrophosphate decahydrate (Na4P2O7*10H2O) occurs as colorless transparent crystals. 
Loses Tetrasodium pyrophosphates water when heated to 93.8°C.

Sodium diphosphate is an inorganic sodium salt comprised of a diphosphate(4-) anion and four sodium(1+) cations.
More commonly known as tetrasodium pyrophosphate, it finds much use in the food industry as an emulsifier and in dental hygiene as a calcium-chelating salt. 
Tetrasodium Pyrophosphate has a role as a food emulsifier and a chelator. 
Tetrasodium Pyrophosphate contains a diphosphate(4-).

Industry Uses of Tetrasodium pyrophosphate
 Adsorbents and absorbents
 Corrosion inhibitors and anti-scaling agents
 Fillers
 Intermediates
 Plating agents and surface treating agents
 Processing aids, not otherwise listed
 Sequestering agent
 Solids separation agents
 Solvents (for cleaning and degreasing)
 Surface active agents


Consumer Uses of Tetrasodium pyrophosphate
 Agricultural products (non-pesticidal)
 Automotive care products
 Building/construction materials not covered elsewhere
 Cleaning and furnishing care products
 Fabric, textile, and leather products not covered elsewhere
 Ink, toner, and colorant products
 Laundry and dishwashing products
 Metal products not covered elsewhere
 Non-TSCA use
 Plastic and rubber products not covered elsewhere
 Water treatment products

General Manufacturing Information
Industry Processing Sectors
 All other basic organic chemical manufacturing
 All other chemical product and preparation manufacturing
 Food, beverage, and tobacco product manufacturing
 Industrial gas manufacturing
 Mining (except oil and gas) and support activities
 Miscellaneous manufacturing
 Plastic material and resin manufacturing
 Primary metal manufacturing
 Services
 Soap, cleaning compound, and toilet preparation manufacturing
 Utilities

IDENTIFICATION AND USE: 
Tetrasodium pyrophosphate is a colorless, transparent crystals or white powder or granules. 
Tetrasodium Pyrophosphate is odorless; slightly soluble in water; insoluble in alcohol and ammonia. 
Tetrasodium pyrophosphate is used as a cleaning compound; oil well drilling; water treatment, cheese emulsification; as a general sequestering agent, to remove rust stains; as am ingredient of one fluid ink eradicators, in electrodeposition of metals. 
Tetrasodium Pyrophosphate is used in textile dyeing; scouring of wool; buffer; food additive; detergent builder; water softener and dispersant.

Description of Tetrasodium pyrophosphate
Sodium pyrophosphate, also called Tetrasodium pyrophosphate or TSPP is used in the laboratory as a buffering agent. 
The compound has been shown to be useful in the preparation of an EDTA-sodium pyrophosphate extraction buffer for microcystin analysis of soil samples. 
Tetrasodium pyrophosphate is an odorless, white powder or granules. 
Tetrasodium Pyrophosphate is used in water softener, buffering agent, thickening agent, dispersing agent, wool de-fatting agent, metal cleaner, soap and synthetic detergent builder, general sequestering agent, in electrodeposition of metals. 
Tetrasodium Pyrophosphate also acts as a tartar control agent in toothpaste and dental floss. 
In addition, Tetrasodium pyrophosphate is used as a chelating agent in antimicrobial studies. 
Tetrasodium Pyrophosphate is also used as a food additive in common foods such as chicken nuggets, crab meat and canned tuna.


Chemical Properties
Tetrasodium pyrophosphate is a white crystalline powder or colourless crystals with the formula Na4P2O7. 
Tetrasodium Pyrophosphate contains the pyrophosphate ion and sodium cation. 
There is also a hydrated form, Na4P2O7.10H2O.
Tetrasodium pyrophosphate is used as a buffering agent, an emulsifier, a dispersing agent, and a thickening agent, and is often used as a food additive. 
Tetrasodium Pyrophosphate is widely used as an emulsifying salt (ES) in process cheese. 
Common foods containing sodium pyrophosphate include chicken nuggets, marshmallows, pudding, crab meat, imitation crab, canned tuna, and soy-based meat alternatives and cat foods and cat treats where it is used as a palatability enhancer. 
Tetrasodium Pyrophosphate is the active ingredient in Bakewell, the substitute for baking powder's acid component marketed during shortages in World War II. 
Tetrasodium Pyrophosphate is also used in some common baking powders.

About Tetrasodium Pyrophosphate
Helpful information
Tetrasodium Pyrophosphate is registered under the REACH Regulation and is manufactured in and / or imported to the European Economic Area, at ≥ 1 000 to < 10 000 tonnes per annum.

Tetrasodium Pyrophosphate is used by consumers, in articles, by professional workers (widespread uses), in formulation or re-packing, at industrial sites and in manufacturing.

Consumer Uses of Tetrasodium pyrophosphate
Tetrasodium Pyrophosphate is used in the following products: pH regulators and water treatment products, water softeners, cosmetics and personal care products, coating products and fillers, putties, plasters, modelling clay. Release to the environment of Tetrasodium Pyrophosphate can occur from industrial use: formulation of mixtures, in the production of articles and in processing aids at industrial sites. Other release to the environment of Tetrasodium Pyrophosphate is likely to occur from: indoor use (e.g. machine wash liquids/detergents, automotive care products, paints and coating or adhesives, fragrances and air fresheners) and outdoor use.

Article service life
Release to the environment of Tetrasodium Pyrophosphate can occur from industrial use: industrial abrasion processing with low release rate (e.g. cutting of textile, cutting, machining or grinding of metal).
Other release to the environment of Tetrasodium Pyrophosphate is likely to occur from: outdoor use in long-life materials with low release rate (e.g. metal, wooden and plastic construction and building materials) and indoor use in long-life materials with low release rate (e.g. flooring, furniture, toys, construction materials, curtains, foot-wear, leather products, paper and cardboard products, electronic equipment).
Tetrasodium Pyrophosphate can be found in products with material based on: stone, plaster, cement, glass or ceramic (e.g. dishes, pots/pans, food storage containers, construction and isolation material), fabrics, textiles and apparel (e.g. clothing, mattress, curtains or carpets, textile toys), leather (e.g. gloves, shoes, purses, furniture), paper (e.g. tissues, feminine hygiene products, nappies, books, magazines, wallpaper), wood (e.g. floors, furniture, toys) and plastic (e.g. food packaging and storage, toys, mobile phones).
Widespread uses by professional workers
Tetrasodium Pyrophosphate is used in the following products: pH regulators and water treatment products, water softeners and cosmetics and personal care products.
Tetrasodium Pyrophosphate is used in the following areas: formulation of mixtures and/or re-packaging, agriculture, forestry and fishing, building & construction work and municipal supply (e.g. electricity, steam, gas, water) and sewage treatment.
Tetrasodium Pyrophosphate is used for the manufacture of: metals, fabricated metal products, chemicals, pulp, paper and paper products, mineral products (e.g. plasters, cement) and machinery and vehicles.
Release to the environment of Tetrasodium Pyrophosphate can occur from industrial use: formulation of mixtures and in the production of articles.
Other release to the environment of Tetrasodium Pyrophosphate is likely to occur from: indoor use (e.g. machine wash liquids/detergents, automotive care products, paints and coating or adhesives, fragrances and air fresheners) and outdoor use.
Formulation or re-packing
Tetrasodium Pyrophosphate is used in the following products: pH regulators and water treatment products, water softeners and polymers.
Release to the environment of Tetrasodium Pyrophosphate can occur from industrial use: formulation of mixtures, in the production of articles, in processing aids at industrial sites and as processing aid.
Other release to the environment of Tetrasodium Pyrophosphate is likely to occur from: indoor use (e.g. machine wash liquids/detergents, automotive care products, paints and coating or adhesives, fragrances and air fresheners) and outdoor use.
Uses at industrial sites
Tetrasodium Pyrophosphate is used in the following products: pH regulators and water treatment products, water softeners and polymers.
Tetrasodium Pyrophosphate is used in the following areas: formulation of mixtures and/or re-packaging, mining and municipal supply (e.g. electricity, steam, gas, water) and sewage treatment.
Tetrasodium Pyrophosphate is used for the manufacture of: chemicals, metals, fabricated metal products, machinery and vehicles and textile, leather or fur.
Release to the environment of Tetrasodium Pyrophosphate can occur from industrial use: in processing aids at industrial sites, formulation of mixtures, in the production of articles and as processing aid.
Other release to the environment of Tetrasodium Pyrophosphate is likely to occur from: indoor use (e.g. machine wash liquids/detergents, automotive care products, paints and coating or adhesives, fragrances and air fresheners) and outdoor use.
Manufacture
Release to the environment of Tetrasodium Pyrophosphate can occur from industrial use: manufacturing of the substance, formulation of mixtures, formulation in materials, in processing aids at industrial sites, in the production of articles and as an intermediate step in further manufacturing of another substance (use of intermediates).


Tetrasodium pyrophosphate (TSPP), also called tetrasodium disphosphate or sodium pyrophosphate, is a synthetic ingredient that can be used as an acid regulator, sequestrant, protein modifier, coagulant, and a dispersing agent in food with the European food additive number E450(iii). 
Tetrasodium Pyrophosphate is gluten free and vegan.

How is Tetrasodium Pyrophosphate made? 
Tetrasodium Pyrophosphate can be produced by the neutralization of phosphoric acid with sodium hydroxide with mol proportions of 2:1.

Food grade Tetrasodium Pyrophosphate exists as two forms, and follows the corresponding chemical formula: 

Tetrasodium Pyrophosphate Anhydrous: Na4P2O7
Tetrasodium Pyrophosphate Decahydrate: Na4P2O7 · 10H2O

What are the uses of Tetrasodium Pyrophosphate?
With the properties of chelating metal ions, increasing protein water holding capacity, PH buffering, stabilization, emulsification, casein thickening and ect, tetrasodium pyrophosphate is widely used in food to improve the gel strength and the tenderness of meat products/analogs. 

Also, Tetrasodium pyrophosphate is used with other phosphates (e.g. sodium hexametaphosphate, sodium acid pyrophosphate) in seafood to increase the water retention. 

Food
Food grade Tetrasodium Pyrophosphate is mainly used in following two functions:

A buffering agent: with the PH value from 9.8 to 10.8 (1% solution), Tetrasodium Pyrophosphate can be used as an alkaline to adjust pH in processed food, pudding and etc.
A calcium sequestrant: Tetrasodium Pyrophosphate can remove naturally occurring calcium ions from proteins and crosslink with proteins, which results in accelerating protein gelation, improving texture (mouthfeel) and reducing cooking loss in meat analog production (e.g. soy protein).
Following food list may contain Tetrasodium Pyrophosphate:

Meat analogs, such as soy or wheat based food, with the appearance, flavor and mouth-feel the same with meat but not made from meat. 
Marshmallows
Pudding
Cheese
Ice cream
Milk protein products
Tuna
Toothpaste
Orally the main purpose of Tetrasodium Pyrophosphate is to prevent the formation of calculus by reducing the deposition of calcium and magnesium on teeth. 
Thus Tetrasodium pyrophosphate is commonly used as the anticalculus component of many tartar-control toothpastes and mouth rinse. 
Disodium pyrophosphate also has the same function.

The top toothpaste manufacturer, Crest also uses it as the anti-tartar ingredient in its whitening expressions

Is Tetrasodium Pyrophosphate Safe to Eat?
Yes, Tetrasodium pyrophosphate almost has no side effects and the safety has been approved by the U.S. Food and Drug Administration (FDA) and European Food Safety Authority (EFSA), as well as the Joint FAO/WHO Expert Committee on Food Additives (JECFA).

FDA
Tetrasodium Pyrophosphate is generally recognized as safe (GRAS) when used as a sequestrant in food in accordance with good manufacturing practice. 

EFSA
Tetrasodium pyrophosphate (E450iii) is an authorized food additive in the European Union (EU) and can be used as a carrier in the preparations of the colour anthocyanins, also applied in the following food categories with the maximum use levels from 5,000-12,000mg/kg:

Refrigerated, prepacked yeast based doughs 
Salted fish of the Gadidae family 
Biscuits and rusks
JECFA
Function Class: food additives, acidity regulator, sequestrant, emulsifier.


White crystalline solid (Ashford, 1994). Solubility in water at 0°C., 0.316 g/l (Budavari, 1996); Solubility in water at 25°C, 6.7 g/l. 
The pH of a 1% solution is 10.2. Insoluble in alcohol.

How Made:
Tetrasodium Pyrophosphate can be prepared by molecular dehydration of dibasic sodium phosphate at 500°C.. 
Sodium phosphates are generally prepared by the partial or total neutralization of phosphoric acid using sodium carbonate or sodium hydroxide. 
Crystals of a specific hydrate can then be obtained by evaporation of the resultant solution within the temperature range over which the hydrate is stable. 
Another way to prepare Tetrasodium Pyrophosphate involves the calcination of sodium tripolyphosphate and a sodium salt. 
The manufacture of the precursors is described in the review of triple superphosphate.

Specific Uses:
The specific use petitioned is as a pH buffer and dough conditioner for use in organic meat alternative products. 
Cereal and baked goods account for the greatest food use of phosphate additives. 
The principalfood uses for tetrasodium pyrophosphate are as an emulsifier, buffer, nutrient, dietary supplement, sequestrant, and texturizer. 
Tetrasodium Pyrophosphate is also used in cleaning compounds, oil well drilling, rust removal, ink erasers, and in electrodeposition on metals.

Action:
Phosphates in general interact with proteins, such as casein, to function as emulsifiers and prevent the separation of both fat and water in cheese.
Casein is precipitated by pyrophosphates to form thick gels. 
This is believed to be the result of the negative ionic charge of pyrophosphate anions reacting with the positively charged cations in casein. 
Pyrophosphates are good sequestrants for copper and iron, which often catalyze oxidation in fruits and vegetable. 
One source notes considerable debate about the mechanisms of phosphate functionality, with reference to water holding capacity of meat and fish. 
The addition of phosphates to muscle food homogenates, raw and cooked meats, in sausages, hams, poultry, and seafood will decrease the amount of drip loss, enhance waterbinding and water holding capacity resulting in enhanced sensory characteristics.

Combinations:
Tetrasodium pyrophosphate is combined with calcium phosphates as leavening agents. 
Tetrasodium Pyrophosphate has a synergistic effect on various foaming agents, such as alkyl polycarboxylates and triethyl citrate. 
Other salts, such as sodium chloride, can have a synergistic effect on water-holding capacity of sodium phosphates. 

Historic Use:
The interaction of shorter chain polyphosphates—including pyrophosphates—with proteins was first known in 1916. 
Industrial manufacturing of pyrophosphates occurred as early as the 1920s. 
Commercial application of polyphosphates for preparing vegetable protein-polyphosphate compounds in food processing appears to date back to the late 1940s. 


Roles Classification 
Chemical Role(s):    
 food emulsifier
 A food additive used to form or maintain a uniform emulsion of two (or more) phases in a food.
 chelator
 A ligand with two or more separate binding sites that can bind to a single metallic central atom, forming a chelate.

Biological Role(s):    
 food thickening agent
 A food additive that is used to increase the viscosity of foodstuffs.
 food emulsifier
 A food additive used to form or maintain a uniform emulsion of two (or more) phases in a food.

Application(s):
 food thickening agent
 A food additive that is used to increase the viscosity of foodstuffs.
 food emulsifier
 A food additive used to form or maintain a uniform emulsion of two (or more) phases in a food.

Applications
Sodium pyrophosphate is used in water softener, detergent, emulsifying agent, metal cleaner and nutritional supplement. 
Tetrasodium Pyrophosphate acts as a buffering agent, thickening agent and dispersing agent. 
Tetrasodium Pyrophosphate also acts as a tartar control agent in toothpaste and dental floss. 
In addition, Tetrasodium pyrophosphate is used as a chelating agent in antimicrobial studies.
Tetrasodium Pyrophosphate is also used as a food additive in common foods such as chicken nuggets, crab meat and canned tuna.

Solubility
Soluble in water. 
Insoluble in ethyl alcohol.

Notes
Hygroscopic. 
Incompatible withstrong oxidizing agents and strong acids.

Odorless, white powder or granules. mp: 995°C. 
Density: 2.53 g/cm3. 
Solubility in water: 3.16 g/100 mL (cold water); 40.26 g/100 mL boiling water. 
Tetrasodium pyrophosphate is used as a wool de-fatting agent, in bleaching operations, as a food additive. 
The related substance tetrasodium pyrophosphate decahydrate (Na4P2O7*10H2O) occurs as colorless transparent crystals. 
Loses its water when heated to 93.8°C.
Formula
Na4O7P2
Formula Weight
265.90
Melting point
988°
Density
2.534
Storage & Sensitivity
Hygroscopic. 
Store under Nitrogen. 
Ambient temperatures.
Solubility
Soluble in water. 
Insoluble in ethyl alcohol.


Use and Manufacturing

Household & Commercial/Institutional Products
• Auto Products
• Commercial / Institutional
• Home Maintenance
• Personal Care
• Pet Care

IN CLEANING CMPD, 
OIL-WELL DRILLING, 
WATER TREATMENT, 
CHEESE EMULSIFICATION; AS GENERAL SEQUESTERING AGENT, 
TO REMOVE RUST STAINS; AS INGREDIENT OF ONE-FLUID INK ERADICATORS, 
IN ELECTRODEPOSITION OF METALS

TEXTILE DYEING; 
SCOURING OF WOOL; 
BUFFER; 
SEQUESTRANT; 
NUTRIENT SUPPLEMENT; 
FOOD ADDITIVE

INDUST & INSTITUTIONAL DETERGENT BUILDER; 
IN WATER TREATMENT; 
IN HOUSEHOLD LAUNDRY DETERGENTS; 
IN PROCESSED CHEESES; 
IN OTHER FOOD APPLICATIONS; 
IN TEXTILE & CLAY PROCESSING, 
ELASTOMERS, & PAPER PROCESSING

 
Notes
Hygroscopic. Incompatible withstrong oxidizing agents and strong acids.

Tetra sodium pyrophosphate, also known as Sodium Pyro phosphate, Tetra sodium phosphate or TSPP, is achemical compound composed of pyrophosphate and sodium ions.

Application :

• Tetra Sodium pyrophosphate is used as a buffering agent, also as an emulsifier and as a dispersing agent
• Tetra Sodium Pyrophosphate also used as a thickening agent and also often used as a food additive
• TSPP is used in common baking powders and also in toothpaste and dental floss as a tartar control
• Sometimes TSPP is also used in household detergents

Sodium Pyrophosphate has been shown to enhance the rate of pyrophosphate hydrolysis by nonenzymatic catlysis and by inorganic pyrophoshatase. 
Pyrophosphoric Acid can be used for the preparation of vanadyl pyrophosphato methoxide cluster anion. 
Pyrophosphoric Acid is used in anion binding of inorganic phosphates due to is ability to form complexes.

Sodium Pyrophosphate Tetrabasic is generally immediately available in most volumes. 
High purity, submicron and nanopowder forms may be considered. 
American Elements produces to many standard grades when applicable, including Mil Spec (military grade); ACS, Reagent and Technical Grade; Food, Agricultural and Pharmaceutical Grade; Optical Grade, USP and EP/BP (European Pharmacopoeia/British Pharmacopoeia) and follows applicable ASTM testing standards. 
Typical and custom packaging is available. 
Additional technical, research and safety (MSDS) information is available as is a Reference Calculator for converting relevant units of measurement.

Product description
Tetrasodium Pyrophosphate powder Food grade is being used in the manufacture of cold pudding, ice cream and some dairy and meat products and other applications.

 

Benefits
We agree, Tetrasodium Pyrophosphate is not very different than the product of any other supplier. 
But our product comes with something extra. 
With a thorough comprehension of legislation and regulations. 
Our knowledge of formalities, a wide range of markets, not to mention our product know-how, are all at your disposal.

BENEFITS
Buffering agent
Emulsifier
Dispersing agent
Sequestrant
Foaming agent
Protein coagulant

APPLICATIONS
Flavoured milk
Buttermilk
Cheese slices
Whipped toppings
Instant puddings
No-bake cheesecakes
Egg yolk products
Sausages
Restructured poultry


Tetrasodium pyrophosphate is a chemical compound formed by the reaction of phosphoric acid with sodium carbonate to create disodium phosphate which is then further heated to obtain the final product.

Let’s think about phosphoric acid for a minute. 
Aside from its use in making food additives, Tetrasodium pyrophosphate is otherwise mainly used to remove rust from metals. 
Really? That doesn’t seem safe at all to be eating; can you imagine what it would do to your insides?

In food, this additive is used as an emulsifier, thickener, dispersing agent, and as a pH buffering agent. 
Tetrasodium Pyrophosphate is typically found in highly processed foods like chicken nuggets, imitation crab, marshmallows, canned tuna, and soy-based meat alternatives – foods you shouldn’t eat much of anyway – if any at all.
The purpose of this ingredient in these foods Tetrasodium pyrophosphate to bind protein and water to keep all of the ground-up substances together. 

Tetrasodium pyrophosphate is also used in commercial products like toothpaste and detergents. 
In toothpaste, Tetrasodium pyrophosphate is used as a method of tartar control which works by removing calcium and magnesium from saliva to prevent binding to the teeth. 
Unfortunately, this same process may be occurring when you eat foods containing this additive and these minerals, and instead of absorbing the necessary minerals, they are being sequestered away to be expelled from the body. 

Commonly found in
chicken nuggets
imitation meat and seafood
canned meat and seafood
marshmallows
soy-based meat substitutes
detergent
toothpaste

Origin(s): Synthetic
Other language: Pyrophosphate de sodium
INCI name: TETRASODIUM PYROPHOSPHATE
EINECS/ELINCS number: 231-767-1
Food additive: E450
Its functions (INCI)
Anticaking : Helps to ensure the fluidity of solid particles and to limit their agglomeration in cosmetic products in powder or hard mass
Buffering : Stabilises the pH of cosmetics
Chelating : Reacts and forms complexes with metal ions that could affect the stability and / or appearance of cosmetic products
Oral care : Provides cosmetic effects to the oral cavity (cleaning, deodorization and protection)

Used as a water softener, detergent, emulsifying agent, metal cleaner, and nutritional supplement


pH regulators and water treatment products
water softeners
cosmetics and personal care products
coating products
fillers
putties
plasters
modelling clay
polishes and waxes

Tetrasodium Pyrophosphate is also used as a buffering agent, an emulsifier, a dispersing agent, and a thickening agent, and is often used as a food additive. 
Common foods containing tetrasodium pyrophosphate include chicken nuggets, marshmallows, pudding, crab meat, imitation crab, canned tuna, and soy-based meat alternatives and cat foods and cat treats where it is used as a palatability enhancer.


IUPAC Names:
Diphosphoric acid, tetrasodium salt
phosphono dihydrogen phosphate
Sodium diphosphate tetrabasic, Tetrasodium pyrophosphate, TSPP, tetra-Sodium diphosphate
Sodium pyrophosphate
tetrasodium (phosphonatooxy)phosphonate
tetrasodium (phosphonooxy)phosphonate
Tetrasodium diphosphate
tetrasodium diphosphate
tetrasodium phosphonato phosphate
TETRASODIUM PYROPHOSPHATE
Tetrasodium Pyrophosphate
Tetrasodium pyrophosphate
tetrasodium pyrophosphate
Tetrasodium Pyrophosphate
Tetrasodium pyrophosphate
tetrasodium pyrophosphate
tetrasodium pyrophosphate (TSPP)
Tetrasodium pyrophosphate decahydrate
tetrasodium;phosphonato phosphate
TSPP


SYNONYMS: 
pyrophosphatedesodium
jiaolinsuanan
pyrophosphatetetrasodique
Sodiumpyrophosphate,anhydrous
sodiumpyrophosphate[na4p2o7]
tetranatriumpyrophosphat
tetrasodiumpyrophosphate,anhydrous
victortspp
Tetrasodium phosphonato phosphate
Diphosphoric acid tetrasodium
Sodium Pyrophosphate(Anhidride)
SODIUM DI
Nsc56751
Pyrophosphate sodium salt
SodiuM Pyrophosphate Anhydrous FCC
SODIUM PYROPHOSPHAYE
Sodium pyrophosphate tetrabasic Vetec(TM) reagent grade, 95%
SodiuM pyrophosphate tetrabasic >=95%
Food Grade Sodium Pyrophosphate Anhydrous
DIPHOSPHORIC ACID TETRASODIUM SALT
DIPHOSPHORIC ACID, TETRASODIUM SALT, DECAHYDRATE
DECAHYDRATE TETRASODIUM PYROPHOSPHATE
TETRA-SODIUM DIPHOSPHATE
TETRA-SODIUM DIPHOSPHATE-10-HYDRATE
TETRA-SODIUM DIPHOSPHATE DECAHYDRATE
TETRASODIUM PYROPHOSPHATE
SODIUM DIPHOSPHATE
SODIUM DIPHOSPHATE DECAHYDRATE
SODIUM DIPHOSPHATE TETRABASIC DECAHYDRATE
SODIUM PYROPHOSPHATE
Sodium phosphate (pyro)
PYROPHOSPHATE TETRASODIUM
Sodium pyrophosphate tetrabasic anhydrous
TetraSodiumPyrophosphateFoodGradeAnhydrous
TetraSodiumPyrophosphateTechGradeAnhydrous
Tetra-SodiumPyrophosphate(Anhydrous)E.P.
sodium diphosphate tetrabasic
sodium pyrophosphate tetrabasic
sodium pyrophosphate, anhydrous, tech.
SODIUMPYROPHOSPHATE,ANHYDROUS,POWDER,FCC
phosphonooxyphosphonic acid
Sodium Pyrophosphate Tetra, 10-Hydrate
Sodium diphosphate tetrabasic, Tetrasodium pyrophosphate
sodium pyophosphate,anhydrous for food
anhydroustetrasodiumpyrophosphate
natriumpyrophosphat
phosphotex
pyro
pyrophosphate
SODIUM PYROPHOSPHATE, 10-HYDRATE
SODIUM PYROPHOSPHATE TETRABASIC DECAHYDRATE
SODIUM TETRAPYROPHOSPHATE
PYROPHOSPHATE INORGANIC
Pyrophosphoric acid,tetrasodiumsalt
TSPP
Diphosphoric acid, sodium salt (1:4)
Sodium pyrophosphate, 99%, for synthesis
Tetrasodium pyrophosphate ISO 9001:2015 REACH

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