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VITAMIN E ACETATE

Vitamin E acetate is often used to reduce the effects of aging, moisturize the skin, and protect against damage from ultraviolet (UV) radiation.
Vitamin E acetate is essential for the proper functioning of the human body and is known for its antioxidant properties, which help protect cells from damage caused by free radicals.
Vitamin E acetate is commonly used in various skincare products, cosmetics, and dietary supplements. 

CAS Number: 7695-91-2
Molecular Formula:    C31H52O3
Molecular Weight: 472.74
EINECS Number: 231-710-0

Synonyms: Vitamin E acetate, alpha-Tocopherol acetate, 58-95-7, Tocopherol acetate, Alfacol, D-alpha-tocopherol acetate, D-ALPHA-TOCOPHERYL ACETATE, Ecofrol, Contopheron, Tofaxin, Econ, Ephynal acetate, (+)-alpha-Tocopherol acetate, Tokoferol acetate, Evipherol, Tocopherex, Tocophrin, Erevit, Gevex, Tocopheryl acetate, Combinal E, Epsilan-M, E-Toplex, E-Ferol, Endo E Dompe, Spondyvit, alpha-Tocopheryl acetate, Copherol 1250, Covitol 1100, Covitol 1360, Vitamin Ealpha acetate, Vitamin E acetate, d-, Nanotopes, Simmyungsaengmosu, NatAc, Tinoderm E, Fertilvit, Natur-E granulate, DL-alpha-Tocopheryl acetate, Lutavit E 50, Ephynal, Juvela, (+)-alpha-Tocopheryl acetate, CCRIS 4389, (R,R,R)-alpha-Tocopheryl acetate, EINECS 200-405-4, UNII-A7E6112E4N, 52225-20-4, D-alpha tocoferil acetate, (2R,4'R,8'R)-alpha-Tocopheryl acetate, A7E6112E4N, DL-alpha-Tocopherylacetate, d-Alpha Tocopheryl Acetate, alpha-Tocopherol acetate, (2R,4'R,8'R)-, RRR-alpha-tocopheryl acetate, (+)-alfa-tocopherol acetate, alpha-tocopheryl acetate, D-, 54-22-8, DTXSID1031096, CHEBI:32321, 9E8X80D2L0, D-|A-Tocopherol acetate, T-3376, d-Vitamin E acetate, Tocopheryl Acetate, d-Alpha, NCGC00166253-02, 2,5,7,8-Tetramethyl-2-(4,8,12-trimethyltridecyl)-6-cromanyl acetate, (+)-, 6-Chromanol, 2,5,7,8-tetramethyl-2-(4,8,12-trimethyltridecyl)-, acetate, (+)-, 6-Cromanol, 2,5,7,8-tetramethyl-2-(4,8,12-trimethyltridecyl)-, acetate, (+)-, 2H-1-Benzopyran-6-ol, 3,4-dihydro-2,5,7,8-tetramethyl-2-(4,8,12-trimethyltridecyl)-, acetate, DTXCID601356, alpha-Tocopherol acetate, all rac, 2H-1-Benzopyran-6-ol, 3,4-dihydro-2,5,7,8-tetramethyl-2-(4,8,12-trimethyltridecyl)-, acetate, (2R-(2*(4R*,8R*)))-, 2H-1-Benzopyran-6-ol, 3,4-dihydro-2,5,7,8-tetramethyl-2-(4,8,12-trimethyltridecyl)-, acetate, [2R-[2R*(4R*,8R*)]]-, 3,4-Dihydro-2,5,7,8-tetramethyl-2-(4,8,12-trimethyltridecyl)-2H-1-benzopyran-6-yl acetate, (2R-(2*(4R*,8R*)))-, DTXSID3021356, DL-alpha-Tocopherylacetate (Vitamin E acetate), D-.alpha.-Tocopherol acetate, ALPHA-TOCOPHEROL ACETATE, D-, ALPHA-TOCOPHEROL ACETATE. D-, Vectan (TN), NSC 755840, NSC-755840, [(2R)-2,5,7,8-tetramethyl-2-[(4R,8R)-4,8,12-trimethyltridecyl]-3,4-dihydrochromen-6-yl] acetate, 2H-1-Benzopyran-6-ol, 3,4-dihydro-2,5,7,8-tetramethyl-2-((4R,8R)-4,8,12-trimethyltridecyl)-, acetate, (2R)-, DL--Tocopherol acetate, J24.807J, SMR000857327, CAS-52225-20-4, MFCD00072042, .alpha.-Tocopheryl acetate, 2H-1-Benzopyran-6-ol, 3,4-dihydro-2,5,7,8-tetramethyl-2-((4R,8R)-4,8,12-trimethyltridecyl)-, 6-acetate, (2R)-, D-.alpha.-Tocopheryl acetate, (+)-.alpha.-Tocopherol acetate, (+)-.alpha.-Tocopheryl acetate, DTXCID60196594, (R,R,R)-.alpha.-Tocopheryl acetate, DL-alpha-Tocopherylacetate (Vitamin E acetate) 10 microg/mL in Acetonitrile, (R)-2,5,7,8-tetramethyl-2-((4R,8R)-4,8,12-trimethyltridecyl)chroman-6-yl acetate, EINECS 231-710-0, MFCD00072052, (2R)-2,5,7,8-tetramethyl-2-[(4R,8R)-4,8,12-trimethyltridecyl]-3,4-dihydro-2H-1-benzopyran-6-yl acetate, 2H-1-Benzopyran-6-ol, 3,4-dihydro-2,5,7,8-tetramethyl-2-(4,8,12-trimethyltridecyl)-, acetate, (2R-(2R*(4R*,8R*)))-, Tocopheryl acetate,alpha, Vitamin E Acetate (D-form), Tocopheryl acetate, D-alpha-, Alpha Tocopheryl Acetate, D-ALPHA TOCOFERIL ACETATE (MART.), D-ALPHA TOCOFERIL ACETATE [MART.], UNII-9E8X80D2L0, BRN 0097512, (2R,4'R,8'R)-.alpha.-Tocopheryl acetate, 2H-1-Benzopyran-6-ol, 3,4-dihydro-2,5,7,8-tetramethyl-2-((4R,8R)-4,8,12-trimethyltridecyl)-, acetate, (2R)-rel-, Tocopherolacetate, alpha-, Tocopherol acetate [JAN], Tocopherol acetate (JP17), CHEMBL1047, SCHEMBL22298, MLS001335985, MLS001335986, DL-ALPHA-TOCOPHEROLACETATE, 2,5,7,8-Tetramethyl-2-(4,8,12-trimethyltridecyl)-3,4-dihydro-2H-chromen-6-yl acetate #, EC 231-710-0, HMS2230C20, (2R,4'R,8'R)-alpha-Tocopherol acetate, [2R-[2R*(4R,8R*)]]-3,4-Dihydro-2,5,7,8-tetramethyl-2-(4,8,12-trimethyltridecyl)-2H-1-benzopyran-6-ol acetate, 5-17-04-00169 (Beilstein Handbook Reference), Acetate, Tocopherol, Tox21_111491, Tox21_111564, Tox21_113467, Tox21_303444, 3,4-Dihydro-2,5,7,8-tetramethyl-2-(4,8,12-trimethyltridecyl)-2H-benzopyran-6-yl acetate, AKOS025117621, Tox21_113467_1, D--Tocopherol acetate, .ALPHA.-TOCOPHEROL ACETATE, D-, CAS-58-95-7, NCGC00095255-08, NCGC00166253-01, NCGC00257504-01, AS-13784, alpha Tocopherol Acetate, d alpha Tocopheryl Acetate, DL-alpha-Tocopherol acetate, >=96% (HPLC), 6-Chromanol, 2,5,7,8-tetramethyl-2-(4,8,12-trimethyltridecyl)-, acetate, D01735, DL-alpha-Tocopherol acetate, analytical standard, [(2R)-2,5,7,8-tetramethyl-2-[(4R,8R)-4,8,12-trimethyltridecyl]chroman-6-yl] acetate, 3,4-Dihydro-2,5,7,8-tetramethyl-2-(4,8,12-trimethyltridecyl)-2H-benzopyran-6-ol, acetate, Q-201933, Vitamin E acetate (unlabeled), W-109259, VITAMIN E ALPHA ACETATE, ECA8C22F-B5D3-4B88-A9B7-AF6C600001BB, (+)- alpha -Tocopherol acetate, DL-alpha-Tocopherol acetate, tested according to Ph.Eur., TOCOPHERYL ACETATE,D-ALPHA, HY-B1278, TOCOPHERYL ACETATE [WHO-DD], Vitamin E acetate, unspecified form, TOCOPHERYL ACETATE, alpha, D-, s3681, Vitamin E (alpha tocopherol acetate), Alpha Tocopheryl Acetate, United States Pharmacopeia (USP) Reference Standard, alpha-Tocopherol acetate, European Pharmacopoeia (EP) Reference Standard, DL-alpha-Tocopherol acetate, certified reference material, TraceCERT(R), CCG-269474, DB14002, (+)-alpha-Tocopherol acetate, BioReagent, suitable for insect cell culture, ~1360 IU/g, .ALPHA.-TOCOPHEROL ACETATE. D-, Tocopheryl Acetate, a, Pharmaceutical Secondary Standard; Certified Reference Material, .ALPHA.-TOCOPHEROL ACETATE [MI], TOCOPHERYL ACETATE, .ALPHA., D-, (2R)-2,5,7,8-tetramethyl-2-[(4R,8R)-4,8,12-trimethyltridecyl]-3,4-dih

Vitamin E acetate, also known as tocopheryl acetate, is a synthetic form of vitamin E. 
Vitamin E acetates are lipid soluble anti-oxidants that protect cell membranes from oxidative damage. 
Vitamin E acetate is the form of tocopherol preferentially absorbed by Homosapiens. 

Vitamin E acetate can inhibit oxidation of linoleate.
α-Tocopheryl acetate (alpha-tocopherol acetate), also known as vitamin E acetate, is a synthetic form of vitamin E. 
It is the ester of acetic acid and Vitamin E acetate.

The U.S. Centers for Disease Control and Prevention says that vitamin E acetate is a very strong culprit of concern in the 2019 outbreak of vaping-associated pulmonary injury (VAPI), but there is not yet sufficient evidence to rule out contributions from other chemicals.
Vaporization of this ester produces toxic pyrolysis products.
At room temperature, Vitamin E acetate is a fat-soluble liquid. 

It has 3 chiral centers and thus 8 stereoisomers. 
Vitamin E acetate is made by esterifying α-tocopherol with acetic acid. 
Vitamin E acetate, is the most common isomer used for various purposes. 

This is because α-tocopherol occurs in nature primarily as Vitamin E acetate.
Vitamin E acetate does not boil at atmospheric pressure and begins to degrade at 240 °C.
Vitamin E acetate can be vacuum distilled: it boils at 184 °C at 0.01 mmHg, at 194 °C (0.025 mmHg) and at 224 °C (0.3 mmHg). 

In practice, it is not degraded notably by air, visible light or UV-radiation. 
Vitamin E acetate has a refractive index of 1.4950–1.4972 at 20 °C.
Vitamin E acetate is hydrolyzed to α-tocopherol and acetic acid under suitable conditions or when ingested by people.

Vitamin E acetate is a specific form of vitamin E that’s often found in skin care products and dietary supplements. 
It’s also known as tocopheryl acetate, tocopherol acetate, or vitamin E acetate.
Vitamin E is known for its antioxidant properties. 

Antioxidants help to protect your body from damaging compounds called free radicals. 
Vitamin E acetate refers to a group of 8 isoprenoid molecules known as tocochromanols. 
Each molecule shares a similar structure with a core hydroxychromane group linked to a phytyl chain of 16 carbon atoms. 

Vitamin E acetate is typically added as viscous oil to multivitamins and skin creams in the form of vitamin E acetate, the combined ester of acetate and α-tocopherol. 
This synthetic analog of Vitamin E acetate is stable, easy to produce, and is hydrolyzed to vitamin E once it enters the body. 
Though vitamin E acetate is common in several consumer products, it has only recently been used as a diluent for THC-containing vape or e-cigarette products. 

Presumably, the additive is used to help with appearance, taste, and production cost.
Vitamin E acetate, known for its antioxidant activities, is protective against cardiovascular disease and some forms of cancer and has also demonstrated immune-enhancing effects. 
Vitamin E acetate may be of limited benefit in some with asthma and rheumatoid arthritis. 

Vitamin E acetate may be helpful in some neurological diseases including Alzheimer's, some eye disorders including cataracts, and diabetes and premenstrual syndrome. 
Vitamin E acetate may also help protect skin from ultraviolet irradiation although claims that it reverses skin aging, enhances male fertility and exercise performance are poorly supported. 
Vitamin E acetate may help relieve some muscle cramps.

Vitamin E acetate has antioxidant activity. 
Vitamin E acetate may also have anti-atherogenic, antithrombotic, anticoagulant, neuroprotective, antiviral, immunomodulatory, cell membrane-stabilizing and antiproliferative actions. 
Vitamin E acetate is a collective term used to describe eight separate forms, the best-known form being alpha-tocopherol. 

Vitamin E acetate is a fat-soluble vitamin and is an important antioxidant. 
Vitamin E acetate acts to protect cells against the effects of free radicals, which are potentially damaging by-products of the body's metabolism. 
Vitamin E acetate is often used in skin creams and lotions because it is believed to play a role in encouraging skin healing and reducing scarring after injuries such as burns. 

There are three specific situations when a Vitamin E acetate deficiency is likely to occur. 
Vitamin E acetate is seen in persons who cannot absorb dietary fat, has been found in premature, very low birth weight infants (birth weights less than 1500 grams, or 3½ pounds), and is seen in individuals with rare disorders of fat metabolism. 
Vitamin E acetate deficiency is usually characterized by neurological problems due to poor nerve conduction. 

Symptoms may include infertility, neuromuscular impairment, menstrual problems, miscarriage and uterine degradation. 
Preliminary research has led to a widely held belief that Vitamin E acetate may help prevent or delay coronary heart disease. 
Antioxidants such as Vitamin E acetate help protect against the damaging effects of free radicals, which may contribute to the development of chronic diseases such as cancer.

Vitamin E acetate also protects other fat-soluble vitamins (A and B group vitamins) from destruction by oxygen. 
Low levels of Vitamin E acetate have been linked to increased incidence of breast and colon cancer.
Vitamin E acetate is derived from vitamin E (alpha-tocopherol) by adding an acetyl group to it. 

This chemical modification makes it more stable and suitable for use in various products, such as supplements and skincare items.
Vitamin E acetate, in its various forms, is known for its antioxidant properties. 
Antioxidants help protect cells from damage caused by free radicals and oxidative stress. 

This protection is thought to have various health benefits.
Vitamin E acetate is commonly used in dietary supplements and is available in different forms, including d-alpha-tocopheryl acetate and dl-alpha-tocopheryl acetate. 
Vitamin E acetate's often included in multivitamin preparations and standalone vitamin E supplements.

In skincare, vitamin E acetate is often used for its potential benefits in reducing the effects of UV damage and helping to maintain healthy skin. 
Vitamin E acetate is commonly found in moisturizers, serums, and other cosmetic products.
Vitamin E acetate is sometimes used in the fortification of food products. 

Vitamin E acetate can be added to various foods and beverages to increase their vitamin E content, which can be beneficial for individuals who may not get enough of this vitamin through their regular diet.
As mentioned earlier, there was a specific issue related to a different form of "vitamin E acetate" that was used in some black-market vaping products. 
This specific compound, which was not intended for inhalation, was associated with serious lung injuries. 

Vitamin E acetate's important to differentiate between this use and the use of vitamin E acetate in dietary supplements and skincare products, where it is intended for ingestion or topical application.
When used according to recommended guidelines and dosages, vitamin E acetate is generally considered safe for most people. 

However, like any supplement or ingredient, it should be used in moderation. 
Excessive intake of vitamin E, in any form, can lead to potential health risks, so it's important to follow product instructions and consult with a healthcare professional when in doubt.
Normally, free radicals form when your body converts food into energy. 

However, free radicals can also come from UV light, cigarette smoke, and air pollution.
In nature, vitamin E comes in the form of tocopheryl or tocotrienol. 
Both tocopheryl and tocotrienol have four forms, known as alpha, beta, gamma, and delta.

Vitamin E acetate is the most active form of vitamin E in humans.
ATA is more stable than AT, meaning Vitamin E acetate can better withstand environmental stresses such as heat, air, and light. 
This makes it ideal for use in supplements and fortified foods because it has a longer shelf life.

Vitamin E Acetate is an active ingredient for use in cosmetic products for the skin and the hair. 
As an in-vivo antioxidant, it protects the cells against free radicals and prevents the peroxidation of body fats. 
Vitamin E acetate is also an effective moisturizing agent and improves the elasticity and smoothness of the skin. 

Vitamin E acetate is particularly suitable for use in sun-protection products and products for daily personal care.
Vitamin E acetate is not oxidized and can penetrate through the skin to the living cells, where about 5% is converted to free tocopherol and provides beneficial antioxidant effects.
Vitamin E acetate is a well-known antioxidant that occurs naturally in vegetables, vegetable oils, seeds, and fruits. 

Vitamin E acetate, an ester of tocopherol (vitamin E), can induce allergic contact dermatitis.
Tocopherol and Vitamin E acetate are used mainly as antioxidants. 
Vitamin E acetate is the ester of acetic acid and tocopherol, a naturally occurring antioxidant and fat-soluble vitamin. 

Vitamin E acetate is a stable ester form of vitamin E, widely used in the formulation of cosmetics for the prevention or correction of skin damage.
Vitamin E acetate is added to these products for its potential benefits in promoting skin health and as an antioxidant. 

Melting point: -28°C
Boiling point: 224 °C0.3 mm Hg(lit.)
Density: 0.96 g/mL at 20 °C (lit.)
vapor density: 16.3 (vs air)
refractive index: n20/D 1.497
Flash point: >230 °F
storage temp.:2-8°C
solubility:Practically insoluble in water, freely soluble in acetone, in anhydrous ethanol and in fatty oils.
form: neat
Specific Gravity: 0.962 (20/4℃)
color: Clear yellow viscous liquid
Odor: Odorless
Water Solubility: Immiscible with water.
Sensitive: Air & Light Sensitive
Merck: 14,9495
BRN: 97512
InChIKey: ZAKOWWREFLAJOT-CEFNRUSXSA-N
LogP: 12.260 (est)

Vitamin E acetate upregulates the expression of cytosolic phospholipase A2 and cyclooxygenase (COX)-1 which in turn enhances the release of prostacyclin. 
Prostacyclin is a vasodilating factor and inhibitor of platelet aggregation and platelet release. 
Vitamin E acetate is also known that platelet aggregation is mediated by a mechanism involving the binding of fibrinogen to the glycoprotein IIb/IIIa (GPIIb/IIIa) complex of platelets. 

Vitamin E acetate is the major membrane receptor protein that is key to the role of the platelet aggregation response. 
Vitamin E acetate is the alpha-subunit of this platelet membrane protein. 
Vitamin E acetate downregulates GPIIb promoter activity which results in reduction of GPIIb protein expression and decreased platelet aggregation. 

Vitamin E acetate has also been found in culture to decrease plasma production of thrombin, a protein which binds to platelets and induces aggregation. 
A metabolite of vitamin E called Vitamin E acetate quinone or alpha-tocopheryl quinone (TQ) is a potent anticoagulant. 
This metabolite inhibits vitamin K-dependent carboxylase, which is a major enzyme in the coagulation cascade.

The neuroprotective effects of Vitamin E acetate are explained by its antioxidant effects. Many disorders of the nervous system are caused by oxidative stress. 
Vitamin E acetate protects against this stress, thereby protecting the nervouse system.
The immunomodulatory effects of Vitamin E acetate have been demonstrated in vitro, where alpha-tocopherol increases mitogenic response of T lymphocytes from aged mice. 

The mechanism of this response by Vitamin E acetate is not well understood, however it has been suggested that vitamin E itself may have mitogenic activity independent of its antioxidant activity.
Lastly, the mechanism of action of Vitamin E acetate's antiviral effects (primarily against HIV-1) involves its antioxidant activity. 
Vitamin E acetate reduces oxidative stress, which is thought to contribute to HIV-1 pathogenesis, as well as to the pathogenesis of other viral infections. 

Vitamin E acetate also affects membrane integrity and fluidity and, since HIV-1 is a membraned virus, altering membrane fluidity of HIV-1 may interfere with its ability to bind to cell-receptor sites, thus decreasing its infectivity.
Vitamin E acetate can be found in two main forms, natural and synthetic. 

Vitamin E acetate (d-alpha-tocopherol) is generally considered more biologically active and is usually labeled with a "d" prefix, such as d-alpha-tocopheryl acetate. 
Synthetic Vitamin E acetate is less active and is labeled with "dl." 
Natural forms are often preferred for supplements, as they are more efficiently utilized by the body.

Vitamin E acetate is known for its antioxidant properties, which help protect cells from damage caused by free radicals. 
Vitamin E acetate is believed to have several potential health benefits, including:
Vitamin E acetate is often used in skincare products due to its ability to moisturize and protect the skin. 

Vitamin E acetate may help reduce signs of aging and skin damage from UV rays.
Some studies suggest that Vitamin E acetate may have a protective effect on heart health by reducing the risk of coronary artery disease.
Vitamin E acetate plays a role in supporting the immune system, helping the body defend against infections and illnesses.

Vitamin E acetate may contribute to maintaining good eye health and reducing the risk of age-related macular degeneration.
Vitamin E acetate helps neutralize harmful free radicals, which can contribute to various chronic diseases.
Vitamin E acetate is naturally present in a variety of foods, including nuts, seeds, vegetable oils (such as wheat germ, sunflower, and safflower oil), green leafy vegetables, and fortified cereals. 

The recommended dietary allowance for Vitamin E acetate varies depending on age, sex, and life stage. 
For most adults, Vitamin E acetate ranges from 15-15 milligrams (mg) per day. 
Pregnant and lactating women may require slightly more.

Vitamin E acetate supplements are commonly available, but they are generally recommended for individuals who have a deficiency or specific medical conditions. 
Taking high doses of vitamin E supplements over a long period is not advisable without consulting a healthcare provider, as it can lead to adverse effects, including bleeding issues.

Excessive intake of Vitamin E acetate can lead to potential health risks, such as increased risk of bleeding, digestive issues, and in some cases, even more serious health problems. 
Vitamin E acetate's important to stay within the recommended daily allowances and consult a healthcare professional before taking high-dose supplements.

Vitamin E acetate, also known simply as tocopheryl acetate, is a synthetic form of vitamin E found in dietary supplements and skin care products. 
Vitamin E acetate is considered the most stable and active form of vitamin E and the best option overall for treating vitamin E deficiency.1
Vitamin E acetate is marketed to prevent several health conditions or diseases. 

Research on tocopheryl acetate and vitamin E supplementation, in general, has not proven many of these health claims.
This article describes the various uses of tocopheryl acetate and what the current research says about its effectiveness. 
Vitamin E acetate also explains the possible risks of tocopheryl acetate.

Vitamin E acetate is the primary form of vitamin E that is preferentially used by the human body to meet appropriate dietary requirements. 
In particular, the RRR-alpha-tocopherol (or sometimes called the d-alpha-tocopherol stereoisomer) stereoisomer is considered the natural formation of alpha-tocopherol and generally exhibits the greatest bioavailability out of all of the alpha-tocopherol stereoisomers. 
Moreover, Vitamin E acetate is a relatively stabilized form of vitamin E that is most commonly used as a food additive when needed 6.

Vitamin E acetate is subsequently most commonly indicated for dietary supplementation in individuals who may demonstrate a genuine deficiency in vitamin E. 
Vitamin E acetate itself is naturally found in various foods, added to others, or used in commercially available products as a dietary supplement.
Although all forms of Vitamin E acetate exhibit antioxidant activity, it is known that the antioxidant activity of vitamin E is not sufficient to explain the vitamin's biological activity.

Vitamin E acetate's anti-atherogenic activity involves the inhibition of the oxidation of LDL and the accumulation of oxLDL in the arterial wall. 
Vitamin E acetate also appears to reduce oxLDL-induced apoptosis in human endothelial cells. 
Oxidation of LDL is a key early step in atherogenesis as it triggers a number of events which lead to the formation of atherosclerotic plaque. 

In addition, Vitamin E acetate inhibits protein kinase C (PKC) activity. 
PKC plays a role in smooth muscle cell proliferation, and, thus, the inhibition of PKC results in inhibition of smooth muscle cell proliferation, which is involved in atherogenesis.
Vitamin E acetate's antithrombotic and anticoagulant activities involves the downregulation of the expression of intracellular cell adhesion molecule(ICAM)-1 and vascular cell adhesion molecule(VCAM)-1 which lowers the adhesion of blood components to the endothelium. 

Uses:
Vitamin E acetate is used as an alternative to tocopherol itself because the phenolic hydroxyl group is blocked, providing a less acidic product with a longer shelf life. 
Vitamin E acetate is believed that the acetate is slowly hydrolyzed after it is absorbed into the skin, regenerating tocopherol and providing protection against the sun's ultraviolet rays.
Vitamin E acetate was first synthesized in 1963 by workers at Hoffmann-La Roche.

Although there is widespread use of Vitamin E acetate as a topical medication, with claims for improved wound healing and reduced scar tissue, reviews have repeatedly concluded that there is insufficient evidence to support these claims.
There are reports of vitamin E-induced allergic contact dermatitis from use of Vitamin E acetate derivatives such as tocopheryl linoleate and tocopherol acetate in skin care products. 

Incidence is low despite widespread use.
Vitamin E acetate has many proposed uses, primarily because of its antioxidant properties, which are thought to protect cells from free radicals.
Vitamin E acetate supplements are commonly used to help individuals meet their recommended daily intake. 

They are available in various forms, including capsules, softgels, and tablets.
These supplements can be used to support overall health, including immune function and antioxidant protection.

Vitamin E acetate is sometimes recommended by healthcare professionals for specific medical conditions, such as vitamin E deficiency or certain neurological disorders.
Skin and Beauty Products:
Vitamin E acetate is frequently used in skincare products such as lotions, creams, and serums.
Vitamin E acetate is valued for its moisturizing properties and potential benefits in reducing signs of aging and protecting the skin from UV damage.

Vitamin E acetate can also be applied topically to address minor skin irritations and promote skin healing.
Vitamin E, including vitamin E acetate, is sometimes added to food products to increase their nutritional value.
Commonly fortified foods include cereals, breakfast bars, and certain beverages.

Vitamin E acetate is used supplements for specific health purposes, such as promoting heart health or reducing the risk of age-related eye conditions.
Vitamin E acetate may also play a role in immune system support, helping the body fight infections and illnesses.
Topical application of Vitamin E acetate-containing creams or ointments is sometimes used to aid in wound healing, particularly for minor burns, cuts, and scars.

Vitamin E acetate is included in various cosmetics, including lipsticks and lip balms, for its moisturizing properties and potential skin benefits.
Vitamin E acetate has been used as a component in some pharmaceutical formulations.
Vitamin E acetate is sometimes used as an antioxidant in food processing to prevent the oxidation of fats and oils.

Vitamin E acetate is sometimes included in shampoos, conditioners, and hair treatments to help promote healthy hair and scalp. It can add shine and moisture to the hair.
Some nail and cuticle creams contain Vitamin E acetate to help strengthen and protect the nails and surrounding skin.
There is some evidence to suggest that Vitamin E acetate may have anti-inflammatory properties, and it has been explored as a complementary therapy for conditions like osteoarthritis and rheumatoid arthritis.

Vitamin E acetate is sometimes included in eye drops or ointments to help relieve dry eyes and protect the ocular surface.
Vitamin E acetate has been studied for its potential role in supporting neurological health, especially in the context of conditions like Alzheimer's disease.
Vitamin E acetate has been investigated for its potential to mitigate skin damage caused by radiation therapy in cancer treatment.

Some research has examined the impact of Vitamin E acetate on male fertility, as it is believed to have antioxidant properties that can protect sperm from damage.
Some individuals take Vitamin E acetate supplements as part of their preventive health regimen to reduce the risk of chronic diseases and promote overall well-being.
Vitamin E acetate supplements are used in animal nutrition to ensure that animals receive adequate nutrition and to address specific health issues.

Vitamin E acetate, when applied topically, may help protect the skin from damage caused by UV rays and can be found in some sunscreens and sunblock products.
Vitamin E acetate is sometimes used as an antioxidant additive in cosmetics, oils, and other products to extend their shelf life by preventing oxidation.
Vitamin E acetate is used as an antioxidant to protect oils, fats, and other substances from oxidative degradation.

Vitamin E acetate oil, which contains vitamin E acetate, is used for various purposes, including skin moisturization, scar reduction, and as a natural preservative for homemade skincare products.
Vitamin E acetate is often incorporated into cosmetic formulations like lip balms, lipsticks, and foundations to help prevent product spoilage and to provide moisture to the skin.

Many anti-aging creams and serums contain Vitamin E acetate, as it is believed to help reduce the appearance of wrinkles and fine lines, in addition to protecting the skin from environmental damage.
Apart from vitamin E acetate, other forms of vitamin E, such as tocopherols, are used in the food industry as natural antioxidants to prevent the spoilage of food products containing fats and oils.

Vitamin E acetate is sometimes combined with other antioxidants, like vitamin C, to create formulations with enhanced antioxidant properties.
Vitamin E acetate-based creams and lotions are often used to alleviate dry and rough skin conditions, such as eczema and psoriasis.
In alternative and complementary medicine, Vitamin E acetate is sometimes recommended for various health purposes, including the management of PMS symptoms, skin disorders, and neurological conditions.

Vitamin E acetate supplements are sometimes used in pet care, especially for dogs, to support their skin and coat health and overall well-being.
Vitamin E acetate oil or products with vitamin E are applied to the scalp and hair to promote hair growth and improve the health and appearance of the hair.
Nail strengtheners and treatments often contain Vitamin E acetate to help fortify and nourish the nails.

Some research suggests that Vitamin E acetate may help improve blood circulation, which can be beneficial in certain medical conditions.
Vitamin E acetate has been studied for its potential benefits in supporting liver health, especially in cases of non-alcoholic fatty liver disease.
vitamin E acetate (tocopherol acetate) is an anti-oxidant with skinmoisturizing activity. 

Given its free-radical scavenging properties, it is useful in uV protective products. 
Vitamin e acetate is commonly used to replace vitamin e because it is more stable and is converted to vitamin e by the body.
Vitamin E acetate occurs naturally in most vegetable oils. 

The highest concentrations are found in com, soybean oils, sunflower seed, wheat germ, rapeseed, alfalfa, and lettuce. 
Vitamin E acetate is claimed to have age-retardant properties. 
May produce erythemamultiforme-like eruptions. 

Vitamin E acetate is used in a number of cosmetic products; creams are used for scars, striae, and bums; in pharmaeeutical ereams and deodorants; as an antioxidant in foods.
Vitamin E acetate is often used in dermatological products such as skin creams. 

Vitamin E acetate is not oxidized and can penetrate through the skin to the living cells, where about 5% is converted to free tocopherol. 
Claims are made for beneficial antioxidant effects.

Safety Profile:
Vitamin E acetate may help maintain good eye health and reduce the risk of age-related macular degeneration.
Vitamin E acetate serves as an antioxidant, protecting cells from damage caused by free radicals and oxidative stress, which is associated with various chronic diseases.
Vitamin E acetate is added to certain food products to increase their nutritional value, particularly in fortified cereals and breakfast bars.

Vitamin E acetate supplements are commonly taken orally to meet daily nutritional requirements or to address deficiencies. 
They come in various forms, such as capsules, softgels, and tablets.
Vitamin E acetate is often used in skincare products, such as lotions, creams, and serums, to provide moisturization and protect the skin from oxidative damage. 

Vitamin E acetate may help reduce the signs of aging and promote healthy skin.
Vitamin E acetate creams and ointments can be applied to wounds, burns, and scars to potentially speed up the healing process and minimize scarring.
Vitamin E acetate is sometimes used to support cardiovascular health by reducing the risk of coronary artery disease. 

However, its effectiveness for this purpose remains a subject of ongoing research.
Vitamin E acetate plays a role in supporting the immune system, helping the body defend against infections and illnesses.

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