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EC / List no.: 203-529-7
CAS no.: 107-88-0
Mol. formula: C8H20O4
1,3-BG (1,3 Butylene Glycol) is an organic compound with the formula CH3CH(OH)CH2CH2OH.
With two alcohol functional groups, the molecule is classified as a diol.
The compound is a colorless, bittersweet, water-soluble liquid.
1,3-BG (1,3 Butylene Glycol) is one of four common structural isomers of butanediol.
Production and uses
Hydrogenation of 3-hydroxybutanal gives 1,3-BG (1,3 Butylene Glycol):
CH3CH(OH)CH2CHO + H2 → CH3CH(OH)CH2CH2OH
Dehydration of 1,3-BG (1,3 Butylene Glycol) gives 1,3-butadiene:
CH3CH(OH)CH2CH2OH → CH2=CH-CH=CH2 + 2 H2O
Occurrence
In biology, 1,3-BG (1,3 Butylene Glycol) is used as a hypoglycaemic agent.
1,3-BG (1,3 Butylene Glycol) can be converted into β-hydroxybutyrate and serve as a substrate for brain metabolism.
1,3-BG (1,3 Butylene Glycol) has been detected, but not quantified, in several different foods, such as green bell peppers, orange bell peppers, pepper (c. annuum), red bell peppers, and yellow bell peppers.
1,3 Butanediol, also referred to as 1,3-BG (1,3 Butylene Glycol), maintains FDA GRAS status as a flavor molecule.
1,3-BG (1,3 Butylene Glycol) is an organic chemical which belongs to the family of secondary alcohols.
At present, 1,3-BG (1,3 Butylene Glycol) is used mainly in surfactants, inks, solvents for natural and synthetic flavoring agents and serves as a co-monomer in manufacturing certain polyurethane and polyester resins.
1,3-BG (1,3 Butylene Glycol) can also serve as a humectant to prevent loss of moisture in cosmetics, particularly in hair sprays and setting lotions.
Besides, 1,3-BG (1,3 Butylene Glycol) is pharmaceutically involved in the production of colchicine derivatives as a anticancer agent and in the synthesis of dual peroxisome proliferator-activated gamma and delta agonists acting as a hypoglycaemic agent, which is effective for the treatment of diabetes.
1,3-BG (1,3 Butylene Glycol) has a sweet flavor with bitter aftertaste and is odorless when pure.
1,3-BG (1,3 Butylene Glycol) is a butanediol compound having two hydroxy groups in the 1- and 3-positions.
1,3-BG (1,3 Butylene Glycol) is a butanediol and a glycol.
Uses:
1,3-BG (1,3 Butylene Glycol) is used in the synthesis of colchicine derivatives as anticancer agents.
Also used in the synthesis of dual peroxisome proliferator-activated gamma and delta agonists acting as euglycem ic agents in the treatment of diabetes.
Its most extensive use is as an intermediate in the manufacture of polyester plasticisers and other chemical products.
1,3-BG (1,3 Butylene Glycol) finds some use as a solvent and humectant, a useful chemical intermediate.
1,3-BG (1,3 Butylene Glycol) has extensive application in the manufacture of structural materials for boats, custom mouldings, and sheets and boards for construction applications.
1,3-BG (1,3 Butylene Glycol) imparts resistance to weathering plus flexibility and impact resistance.
1,3-BG (1,3 Butylene Glycol) is also used in the manufacture of saturated polyesters for polyurethane coatings, where the glycol imparts greater flexibility to the polyester molecule.
1,3-BG (1,3 Butylene Glycol) is currently used in many personal care products.
1,3-BG (1,3 Butylene Glycol) acts as a co-monomer in the production of polyurethane and polyester resins.
1,3-BG (1,3 Butylene Glycol) is used as a humectant (to prevent loss of moisture) in cosmetics, especially in hair sprays and setting lotions.
1,3-BG (1,3 Butylene Glycol) is used in surfactants, inks, solvents for natural and synthetic flavorings.
1,3-BG (1,3 Butylene Glycol) is involved in the synthesis of dual peroxisome proliferator-activated gamma and delta agonists acting as euglycemic agents, which is used in the treatment of diabetes.
Used as an intermediate in the manufacture of polyester plasticizers, as a humectant for cellophane and tobacco, in polyurethanes and special polyester resins, in surface active agents, as a coupling agent, as a solvent, as a food additive and flavoring, in the cosmetics and pharmaceutical industries as a glycerin substitute, for deicing of aircraft.
1,3-BG (1,3 Butylene Glycol) (BD) is a 1,3-diol. Its vapor pressure upto 270kPa, liquid-phase densities over a temperature range, two-phase (liquid + vapor) heat capacities, critical temperature and critical density have been determined.
The obtained data was employed to derive various thermophysical properties.
Pharmaceutical Applications
Butylene glycol is used as a solvent and cosolvent for injectables. 1,3-BG (1,3 Butylene Glycol) is used in topical ointments, creams, and lotions, and it is also used as a vehicle in transdermal patches.
Butylene glycol is a good solvent for many pharmaceuticals, especially estrogenic substances.
In an oil-in-water emulsion, butylene glycol exerts its best antimicrobial effects at ～8% concentration.
Higher concentrations above 16.7% are required to inhibit fungal growth.
Intermediate in manufacture of polyester plasticizers; humectant for cellophane, tobacco.
Has some mold inhibiting action.
Polyesters, polyurethanes, surface active agents; plasticizers, humectant, coupling agent, solvent, food additive, flavoring.
Industry Uses
• Intermediates
• Solvents (which become part of product formulation or mixture)
Uses Household & Commercial/Institutional Products
• Auto Products
• Inside the Home
• Personal Care
Methods of Manufacturing HelpNew Window
Acetaldol is prepared by acetaldehyde self-condensation in aqueous alkaline solutions. Acetaldehyde conversion cannot be carried higher than 66.6% because aldol and acetaldehyde combine to yield 2,6-dimethyl-1,3-dioxan-4-ol.
The bound acetaldehyde is held so tenaciously that most commercial aldol is essentially equivalent to 2,6-dimethyl-1,3-dioxan-4-ol:
Higher condensation products are often present.
1,3-BG (1,3 Butylene Glycol) is difficult to decompose 2,6-dimethyl-1,3-dioxan-4-ol into aldol without simultaneously dehydrating it to crotonaldehyde.
Steam stripping is one of the most practical ways of removing the bound acetaldehyde.
Aldol is led directly to a hydrogenation system where it is reduced in the presence of Raney nickel or other catalysts.
Any of the acetaldehyde or 2,6-dimethyl-1,3-dioxan-4-ol left is reduced to ethanol and 2,4-dimethyl-1,3-dioxane, both of which are efficiency losses for the process.
Low-boilers are striped from the hydrogenated product and pure 1,3-BG (1,3 Butylene Glycol) is obtained by distillation under reduced pressure.
General Manufacturing Information
Industry Processing Sectors
• All other basic organic chemical manufacturing
• All other chemical product and preparation manufacturing
• Plastic material and resin manufacturing
1,3-BG (1,3 Butylene Glycol) is a natural diol, very pure, clear and odourless liquid.
1,3-BG (1,3 Butylene Glycol) is a common humectant used in cosmetic as moisturizer for the skin, solvent, fragrance enhancer.
The bio-Butylene Glycol is COSMOS approved.
1,3-BG (1,3 Butylene Glycol) is well known in cosmetic for its good moisturizing proprieties and for improving preservative systems.
1,3-BG (1,3 Butylene Glycol) inhibits gram-positive and gram-negative microorganisms as well as moulds and yeasts.
1,3-BG (1,3 Butylene Glycol) is water soluble at room temperature and can be added directly in aqueous phase.
1,3-BG (1,3 Butylene Glycol) is an organic chemical, an alcohol.
1,3-BG (1,3 Butylene Glycol) is commonly used as a solvent for food flavouring agents and is a co-monomer used in certain polyurethane and polyester resins.
1,3-BG (1,3 Butylene Glycol) is one of four stable isomers of butanediol.
1,3-BG (1,3 Butylene Glycol) is also used as a hypoglycaemic agent.
Chemical Properties
Appearance: Colourless Liquid
Boiling Point: 203-204 °C
CAS Number: 107-88-0
ChEBI: 52683
Chemical Composition: Propylene-->Butyraldehyde-->Aldol
Density: 1.005 g/ml
EINECS Number: 203-529-7
HS Code: 29053920
IUPAC Name: Butane-1,3-diol
InChI: 1/C4H10O2/c1-4(6)2-3-5/h4-6H,2-3H2,1H3
InChIKey: PUPZLCDOIYMWBV-UHFFFAOYAC
Melting Point: -54 °C
Molar Mass: 90.12 g/mol
Molecular Formula: C4H10O2
NFPA 704: H-1,F-1,R-0,C-NA
RTECS Number: EK0440000
Refractive: 1.44 n20/D
Related Compounds: 2-Methylpentane
Solubility: Soluble
Synonyms: (±)-Butane-1,3-Diol;1,3-Butandiol;1,3-Butanodiol;1,3-Butylene;1,3-Butylenglykol;1,3-Dihydroxybotane;1-Methyl-1,3-Propanediol;Bd
1.3 BUTYLENE GLYCOL is a emollient, food additive, humectant, solvent.
1,3-BG (1,3 Butylene Glycol) is used in shampoos, body washes, acne treatments, facial cleaner, cosmetics, anti-aging creams, flavors, nail polish, sunscreens
1,3-BG (1,3 Butylene Glycol) by Kyowa Chemical Industry acts as a solvent.
1,3-BG (1,3 Butylene Glycol) is used as an alternative for propylene glycol. Possesses anti-microbial effect.
1,3-BG (1,3 Butylene Glycol) inhibits the drying out of cosmetics and prevents the crystallization of insoluble components.
Aids in solubilizing aqueous insoluble ingredients and stabilizes volatile compounds such as fragrances and fixing them in the cosmetic formulation.
1,3-BG (1,3 Butylene Glycol) contributes to the preservation of products against spoiling, it has a very good distribution coefficient and thus leads to better efficacy of preservatives mixed into formulation.
1,3-BG (1,3 Butylene Glycol) is used in various cosmetics and personal care products.
1,3-BG (1,3 Butylene Glycol), also known as b-butylene glycol or BD, belongs to the class of organic compounds known as secondary alcohols.
Secondary alcohols are compounds containing a secondary alcohol functional group, with the general structure HOC(R)(R') (R,R'=alkyl, aryl).
1,3-BG (1,3 Butylene Glycol) is a bitter and odorless tasting compound.
1,3-BG (1,3 Butylene Glycol) has been detected, but not quantified, in several different foods, such as green bell peppers, orange bell peppers, pepper (c. annuum), red bell peppers, and yellow bell peppers.
This could make 1,3-BG (1,3 Butylene Glycol) a potential biomarker for the consumption of these foods.
A butanediol compound having two hydroxy groups in the 1- and 3-positions.
1,3-BG (1,3 Butylene Glycol) is a viscosity decreasing component.
Like other humectants, it forms a barrier which prevents the drying out of cosmetics.
Furthermore, it prevents the assimilation of water from atmospheres of high humidity into film-forming preparations.
1,3-BG (1,3 Butylene Glycol) has a solubilising effect on natural and synthetic flavouring substances.
Among the most important characteristics of this ingredient are its ability to stabilise volatile compounds such as fragrances and flavours fixing them in cosmetic formulations and to retard the loss of aroma.
Alternative solvent to Propylene Glycol or Glycerol superior in technological and biological effects.
Viscosity decreasing.
As humectant, it prevents the drying out of cosmetics.
1,3-BG (1,3 Butylene Glycol) prevents the assimilation of water from atmospheres of high humidity into film-forming preparations.
Prevents crystallization of insolubles
Compared with Glycerol, Sorbitol, and Propylene Glycol, more efficient polyol as antimicrobial agent.
Inhibits gram-positive and gram-negative microorganisms as well as molds and yeasts, but is not sporicidal.
All polyols need a contact period of at least one week to exert their effect as preservatives.
optimal antimicrobial effect when e.g. added to an oil in water emulsion at 8 %.
1,3-BG (1,3 Butylene Glycol) has been shown to inhibit growth of escherichia coli, sal.
Yyphiosa and pseudomonas aeruginosa, whereas funghi areinhibited only above 17 %.
Butylene glycol, or let’s just call it BG, is a multi-tasking colorless, syrupy liquid.
It’s a great pick for creating a nice feeling product.
BG’s main job is usually to be a solvent for the other ingredients.
Other tasks include helping the product to absorb faster and deeper into the skin (penetration enhancer), making the product spread nicely over the skin (slip agent), and attracting water (humectant) into the skin.
1. Flavor / Flavoring / Flavor Enhancer - Provides or enhances a particular taste or smell.
2. Fragrance / Fragrance Component - Provides or enhances a particular smell or odor.
3. Humectant - Binds with water to increase skin hydration. Also enhances water absorption of the skin
4. Slip Modifier - Increases spreadability of other ingredients
5. Solvent (Cosmetics) - Enhances the properties of other ingredients
6. Viscosity Controlling Agent - Maintains or alters the thickness of a liquid, mostly used in cosmetics
1,3-BG (1,3 Butylene Glycol) (also known as 1,3-butylene glycol, butane-1,3-diol, or 1,3-dihydroxybutane) is an organic chemical, a diol.
1,3-BG (1,3 Butylene Glycol) is commonly used as a solvent for food flavoring agents and in the manufacturing of resins.
Butylene glycol is used as solvents and viscosity decreasing agents in cosmetics and personal care products.
1,3-BG (1,3 Butylene Glycol) is used in the formulation of hair and bath products, eye and facial makeup, fragrances, personal cleanliness products, and shaving and skin care products.
This is an Unapproved E-number (E1502).
About 1,3-BG (1,3 Butylene Glycol)
Helpful information
1,3-BG (1,3 Butylene Glycol) is registered under the REACH Regulation and is manufactured in and / or imported to the European Economic Area, at ≥ 1 000 to < 10 000 tonnes per annum.
1,3-BG (1,3 Butylene Glycol) is used by consumers, in articles, by professional workers (widespread uses), in formulation or re-packing, at industrial sites and in manufacturing.
Consumer Uses
1,3-BG (1,3 Butylene Glycol) is used in the following products, cosmetics and personal care products, perfumes and fragrances, washing & cleaning products and pharmaceuticals.
Other release to the environment of 1,3-BG (1,3 Butylene Glycol) is likely to occur from, indoor use (e.g. machine wash liquids/detergents, automotive care products, paints and coating or adhesives, fragrances and air fresheners) and outdoor use as processing aid.
Article service life
Other release to the environment of 1,3-BG (1,3 Butylene Glycol) is likely to occur from, indoor use in long-life materials with low release rate (e.g. flooring, furniture, toys, construction materials, curtains, foot-wear, leather products, paper and cardboard products, electronic equipment).
1,3-BG (1,3 Butylene Glycol) can be found in products with material based on: paper (e.g. tissues, feminine hygiene products, nappies, books, magazines, wallpaper).
Widespread uses by professional workers
1,3-BG (1,3 Butylene Glycol) is used in the following products: cosmetics and personal care products, laboratory chemicals, metal surface treatment products, adhesives and sealants, fillers, putties, plasters, modelling clay, non-metal-surface treatment products and lubricants and greases.
1,3-BG (1,3 Butylene Glycol) is used in the following areas: health services, scientific research and development and formulation of mixtures and/or re-packaging.
Release to the environment of 1,3-BG (1,3 Butylene Glycol) can occur from industrial use, formulation of mixtures.
Other release to the environment of 1,3-BG (1,3 Butylene Glycol) is likely to occur from, indoor use (e.g. machine wash liquids/detergents, automotive care products, paints and coating or adhesives, fragrances and air fresheners) and outdoor use as processing aid.
Formulation or re-packing
1,3-BG (1,3 Butylene Glycol) is used in the following products, cosmetics and personal care products, pharmaceuticals, textile treatment products and dyes, washing & cleaning products, metal surface treatment products, adhesives and sealants, fillers, putties, plasters, modelling clay and non-metal-surface treatment products.
Release to the environment of 1,3-BG (1,3 Butylene Glycol) can occur from industrial use, formulation of mixtures and formulation in materials.
Uses at industrial sites
1,3-BG (1,3 Butylene Glycol) is used in the following products: polymers, pharmaceuticals, laboratory chemicals, non-metal-surface treatment products and paper chemicals and dyes.
1,3-BG (1,3 Butylene Glycol) has an industrial use resulting in manufacture of another substance (use of intermediates).
1,3-BG (1,3 Butylene Glycol) is used in the following areas, health services and scientific research and development.
1,3-BG (1,3 Butylene Glycol) is used for the manufacture of, plastic products, chemicals, pulp, paper and paper products and machinery and vehicles.
Release to the environment of 1,3-BG (1,3 Butylene Glycol) can occur from industrial use, as an intermediate step in further manufacturing of another substance (use of intermediates), for thermoplastic manufacture, as processing aid, in the production of articles and in processing aids at industrial sites.
Manufacture
Release to the environment of 1,3-BG (1,3 Butylene Glycol) can occur from industrial use: manufacturing of the substance.
IUPAC NAMES:
(+/-)-Butane-1,3-diol
(3R)-butane-1,3-diol; (3S)-butane-1,3-diol
1,3-BUTANEDIOL
1,3-Butanediol
1,3-BUTYLENE GLYCOL
1,3-Butylene glycol
1,3-Butylene Glycol
1,3-Butylene glycol
Butan-1,3-diol
Butane-1,2 diol
Butane-1,3-diol
butane-1,3-diol
Butane-1,3-diol
Butane-1,3-diol (1,3-BUTANEDIOL (8CI9CI))
Butylene glycol
SYNONYMS:
(±)-butane-1,3-diol
1,3-Butandiol
Methyltrimethylene
Methyltrimethylene glycol
methyltrimethyleneglycol
1-METHYLTRIMETHYLENE GLYCOL
1,3-DIHYDROXYBUTANE
(+/-)-1,3-BUTANEDIOL
1,3-BUTANEDIOL
1,3-BUTYLENE GLYCOL
1,3-BUTANEDIOL, REAGENTPLUS, 99%
1,3-BUTANEDIOL, ANHYDROUS, 99+%
(q) -1,3-Butanediol 4 M Solution
1,3-BUTANEDIOL, 99+%
1,3Butanediol,98%
1,3-butan-diol (=1,3-butylene glycol)
(n)-1,3-butanediol
1,3-butanediole
1,3-butylenglycol
RS-1,3-BUTANEDIOL
BUTAN-1,3-DIOL
BUTYLENGLYKOL-1,3
1,3-BUTANEDIOL GR
1,3-BUTANEDIOL CP
1,3-BUTYLENE GLYCOL FCC
Daicel 1,3-Butylene Glycol
(+/-)-1,3-Butanediol ReagentPlus(R), 99.5%
(+/-)-1,3-Butanediol Vetec(TM) reagent grade, 98%
B-BUTYLENE GLYCOL
(3S)-butane-1,3-diol
1,3-Butandiol Msynthplus
1,3-Butanediol, 99%, SuperDry, water≤30 ppm, J&KSeal
3-Butanediol
1,3-Butanodiol
1,3-butylene
1,3-Butylenglykol
1,3-Dihydroxybotane
1,3-Butaneiol
1-Methyl-1,3-propanediol
BD
beta-Butylene glycol
beta-butyleneglycol
butane-1,
butane-1,3-
Butane-1,3-diol
1,3-Butanediol [for BiocheMical Research]
[for BiocheMical Research]
1,3-Butanediol
(§1)-1,3-Butanediol, 99%, pure
(§1)-1,3-Butanediol, pure, 99%
1,3-BUTANEDIOL FOR SYNTHESIS
1,3-Butylene Glycol 1,3-Dihydroxybutane
()-1,3-Butanediol, 99%, pure
1,3-Butanediol, 99%, SpcDry, Water≤50 ppM (by K.F.), SpcSeal
1,3-Butanediol, 99%, SpcDry, with Molecular sieves, Water≤50 ppM (by K.F.), SpcSeal
(±)-1,3-Butanediol 4 M solution
(±)-1,3-Butanediol solution
Additive Screening Solution 03/Fluka kit no 78374
1,3-Butanediol [ACD/Index Name] [ACD/IUPAC Name]
&β;-butylene glycol
(±)-1,3-Butanediol
(RS)-1,3-Butandiol
1,3-Butandiol [German] [ACD/IUPAC Name]
1,3-Butanediol [French] [ACD/Index Name] [ACD/IUPAC Name]
1,3-Butylene glycol
1,3-Butylenglykol [German]
1,3-Dihydroxybutane
107-88-0 [RN]
1731276 [Beilstein]
1-Methyl-1,3-propanediol
203-529-7 [EINECS]
Butane-1,3-diol
Butylene glycol
EK0440000
MFCD00004554 [MDL number]
QY1 & 2Q [WLN]
UNII:3XUS85K0RA
"1,3-BUTANEDIOL"|"BUTANE-1,3-DIOL"
"BUTANE-1,3-DIOL"
(±)-1,3-Butanediol
(±)-1，3-butanediol
(±)-1,3-Butylene glycol
(±)-1,3-Butylene glycol
(R)-Butane-1,3-diol
(RS)-1,3-Butanediol
(S)-butane-1,3-diol
1,3-BG (1,3 Butylene Glycol)
1,3-Butanodiol
1,3-Butylenglykol
BD
Butanediol,1,3-
Butylene Glycol (Butane-1,3-diol)
MFCD00064278 [MDL number]
