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1,4-Dimethylpiperazine (DMP) is used in the synthesis of cationic surfactants and other chemical compounds.
1,4-Dimethylpiperazine (DMP) is utilized in the synthesis of layered zirconium phosphates and other specialized materials.
1,4-Dimethylpiperazine (DMP) is used as a drug: A catalyst that is used for polyurethane foams and intermediate for cationic surfactants.
CAS Number: 106-58-1
EC Number: 203-412-0
MDL number: MFCD00006156
Product Type: Polymerization Initiators / Inhibitors / Catalysts > Catalysts
Chemical Composition: 1,4-dimethylpiperazine
Molecular Formula: C6H14N2
Molecular Weight: 114.19 g/mol
SYNONYMS:
1,4-Dimethylpiperazine, N,N'-dimethylpiperazine, 106-58-1, Lupetazine, PIPERAZINE, 1,4-DIMETHYL-, Texacat DMP, 1,4-dimethyl-piperazine, MFCD00006156, 14-dimethylpiperazine, DTXSID8051544, TF146U602L, NSC-41177, CCRIS 6690, EINECS 203-412-0, NSC 41177, UNII-TF146U602L, 1,4-dimethyl-2,3,5,6-tetrahydropyrazine, Piperazine,4-dimethyl-, N,N'-Dimethyipiperazine, 1, 4-Dimethylpiperazine, N,N'-di-methylpiperazine, N,N/'-Dimethylpiperazine, EC 203-412-0, SCHEMBL1069, N,N-DIMETHYLPIPERAZINE, 1,4-Dimethylpiperazine, 98%, SCHEMBL7539180, CHEMBL3560545, DTXCID9030096, NSC41177, Tox21_303778, AKOS005206832, NCGC00357070-01, CAS-106-58-1, PS-11956, D0787, NS00004327, EN300-16247, Q26840929, Z103703012, DIETHYLCARBAMAZINE CITRATE IMPURITY B [EP IMPURITY], InChI=1/C6H14N2/c1-7-3-5-8(2)6-4-7/h3-6H2,1-2H, 1,4-Dimethylpiperazine, Lupetazine, N,N'-Dimethyipiperazine, N,N'-Dimethylpiperazine, Texacat DMP, piperazine, N,N'-dimethyl-, 1,4-Dimethylpiperazine, N,N'-dimethylpiperazine, 106-58-1, Lupetazine, PIPERAZINE, 1,4-DIMETHYL-, Texacat DMP, 1,4-dimethyl-piperazine, MFCD00006156, 14-dimethylpiperazine, DTXSID8051544, TF146U602L, NSC-41177, CCRIS 6690, EINECS 203-412-0, NSC 41177, UNII-TF146U602L, 1,4-dimethyl-2,3,5,6-tetrahydropyrazine, Piperazine,4-dimethyl-, N,N'-Dimethyipiperazine, 1, 4-Dimethylpiperazine, N,N'-di-methylpiperazine, N,N/'-Dimethylpiperazine, EC 203-412-0, SCHEMBL1069, N,N-DIMETHYLPIPERAZINE, 1,4-Dimethylpiperazine, 98%, SCHEMBL7539180, CHEMBL3560545, DTXCID9030096, NSC41177, Tox21_303778, AKOS005206832, NCGC00357070-01, CAS-106-58-1, PS-11956, D0787, NS00004327, EN300-16247, Q26840929, Z103703012, DIETHYLCARBAMAZINE CITRATE IMPURITY B [EP IMPURITY], InChI=1/C6H14N2/c1-7-3-5-8(2)6-4-7/h3-6H2,1-2H, 1,4-Dimethylpiperazine, N,N'-Dimethylpiperazine, Lupetazine, Texacat DMP, Jeffcat DMP, Lupragen N204, PC CAT DMP, Addocat 117, Gel balance catalyst, Polyurethane foaming gel balance catalyst, 1,4-dimethylpiperazine, DMP, Lupragen N204, PC CAT DMP, Addocat 117, Gel Balance Catalyst, Polyurethane Foaming Gel Balance Catalyst, 1,4-Dimethylpiperazine, 1,4-Dimethylpiperazine, Lupetazine, N,N′-Dimethylpiperazine, Texacat DMP, n,n'-dimethylpiperazine, lupetazine, piperazine, 1,4-dimethyl, texacat dmp, unii-tf146u602l, ccris 6690, 1,4-dimethyl-piperazine, 1,4-dimethyl-2,3,5,6-tetrahydropyrazine, 1,4-dimethylpiperazin, pubchem8569, Lupetazine, N,N'-Dimethylpiperazine, 1,4-Dimethylpiperazine, N,N'-Dimethyipiperazine, Texacat DMP, 1,4-Dimethylpiperazine, Lupetazine, N,N'-Dimethylpiperazine, Texacat DMP, Piperazine, 1,4-dimethyl-,
1,4-Dimethylpiperazine (DMP) is a six-membered heterocyclic compound with the molecular formula C₆H₁₄N₂ and a molecular weight of 114.19 g/mol.
1,4-Dimethylpiperazine (DMP) is a colorless to pale yellow liquid with a boiling point of ~131°C and a pH of 10 (100 g/L in water, 20°C).
1,4-Dimethylpiperazine (DMP)'s structure features two methyl groups at the 1 and 4 positions of the piperazine ring, reducing the basicity of the nitrogen atoms compared to unsubstituted piperazine.
1,4-Dimethylpiperazine (DMP) is a heterocyclic organic compound with the molecular formula C₆H₁₄N₂.
1,4-Dimethylpiperazine (DMP) consists of a six-membered ring containing two nitrogen atoms at opposite positions.
The nitrogen atoms in 1,4-Dimethylpiperazine (DMP) are methylated at the 1 and 4 positions, which influences its chemical properties compared to unsubstituted piperazine.
1,4-Dimethylpiperazine (DMP) appears as a colorless to pale yellow liquid at room temperature.
1,4-Dimethylpiperazine (DMP) has a boiling point of approximately 131°C and exhibits basicity, with a pH of about 10 in aqueous solution.
Due to its chemical structure, 1,4-Dimethylpiperazine (DMP) has lower basicity than piperazine because of the electron-donating effect of the methyl groups.
1,4-Dimethylpiperazine (DMP) is widely used as an intermediate and building block in various chemical syntheses.
USES and APPLICATIONS of 1,4-DIMETHYLPIPERAZINE (DMP):
Polyurethane Catalyst: 1,4-Dimethylpiperazine (DMP) is employed in the production of polyurethane foams.
Chemical Intermediate: 1,4-Dimethylpiperazine (DMP) is used in the synthesis of cationic surfactants and other chemical compounds.
Research and Development: 1,4-Dimethylpiperazine (DMP) is utilized in the synthesis of layered zirconium phosphates and other specialized materials.
1,4-Dimethylpiperazine (DMP) is used as a drug: A catalyst that is used for polyurethane foams and intermediate for cationic surfactants.
1,4-Dimethylpiperazine (DMP) is widely used in polyurethane resins, surfactants, and pharmaceutical linkers, particularly in PROTACs (proteolysis-targeting chimeras).
1,4-Dimethylpiperazine (DMP) is extensively used in the manufacture of polyurethane resins as a curing agent or chain extender.
1,4-Dimethylpiperazine (DMP) contributes to the mechanical strength and chemical resistance of polyurethane materials.
In the surfactant industry, 1,4-Dimethylpiperazine (DMP) serves as a raw material for producing specialty surfactants.
1,4-Dimethylpiperazine (DMP) is employed as a pharmaceutical linker, particularly in the synthesis of PROTACs (proteolysis-targeting chimeras), which are emerging drug candidates for targeted protein degradation.
1,4-Dimethylpiperazine (DMP)’s low toxicity and favorable reactivity make it suitable for these advanced pharmaceutical applications.
Additionally, 1,4-Dimethylpiperazine (DMP) finds use in agrochemical production and polymer industries due to its versatility.
1,4-Dimethylpiperazine (DMP) is also used in coating formulations and adhesives to enhance performance properties.
1,4-Dimethylpiperazine (DMP)'s liquid state at room temperature facilitates easy handling and processing in industrial settings.
-Applications of 1,4-Dimethylpiperazine (DMP) in Drug Development:
1,4-Dimethylpiperazine (DMP) serves as a versatile building block in medicinal chemistry:
*Drug Design :
1,4-Dimethylpiperazine (DMP) is often incorporated into drug candidates due to its ability to enhance solubility and bioavailability.
1,4-Dimethylpiperazine (DMP) is commonly used in the synthesis of various pharmaceutical compounds, including antihistamines and antidepressants.
*PROTAC Development :
In recent research, 1,4-Dimethylpiperazine (DMP) has been utilized in the design of PROTACs (proteolysis-targeting chimeras), which are innovative therapeutic agents aimed at selectively degrading target proteins involved in disease processes.
-1,4-Dimethylpiperazine (DMP) has a wide range of applications in scientific research:
*Chemistry:
1,4-Dimethylpiperazine (DMP) is used as a catalyst for polyurethane foams and as an intermediate for cationic surfactants.
*Biology:
1,4-Dimethylpiperazine (DMP) is used in the synthesis of various biologically active compounds.
*Medicine:
1,4-Dimethylpiperazine (DMP) serves as an intermediate in the synthesis of pharmaceuticals, including drugs with piperazine moieties.
*Industry:
1,4-Dimethylpiperazine (DMP) is used in the production of polymers and as a stabilizer in various industrial processes.
KEY CHARACTERISTICS AND BENEFITS OF 1,4-DIMETHYLPIPERAZINE (DMP):
✅ 1. Efficient Catalyst in Polyurethane Production
Benefit:
1,4-Dimethylpiperazine (DMP) is widely used as a tertiary amine catalyst in the formulation of polyurethane foams, especially flexible and semi-rigid foams.
Advantage:
1,4-Dimethylpiperazine (DMP) promotes the reaction between polyol and isocyanate, accelerating curing and enhancing foam quality and consistency.
✅ 2. Versatility in Chemical Synthesis
Benefit:
1,4-Dimethylpiperazine (DMP) acts as a building block in organic synthesis.
Example Uses of 1,4-Dimethylpiperazine (DMP): Pharmaceutical intermediates, Agrochemical products, and Surfactants and emulsifiers.
Advantage:
Its symmetrical and methylated structure makes 1,4-Dimethylpiperazine (DMP) useful for designing other nitrogen-containing compounds.
✅ 3. Good Water Solubility
Benefit:
Its miscibility with water and many organic solvents makes 1,4-Dimethylpiperazine (DMP) easy to incorporate into aqueous formulations.
Application:
1,4-Dimethylpiperazine (DMP) is often used in lab-scale and industrial-scale aqueous reactions.
✅ 4. Basicity and Buffering Capacity
Characteristic:
1,4-Dimethylpiperazine (DMP) is a moderately strong base (due to the amine groups).
Benefit:
1,4-Dimethylpiperazine (DMP) can act as a buffering agent or neutralizing base in reactions or formulations that require pH control.
✅ 5. Low Viscosity and Fast Reactivity
Characteristic:
1,4-Dimethylpiperazine (DMP) has low viscosity, which allows for easy handling and rapid diffusion in formulations.
Benefit:
1,4-Dimethylpiperazine (DMP) enhances efficiency in production lines due to its liquid, low-viscosity nature.
✅ 6. High Purity Available
Industrial grades of 1,4-Dimethylpiperazine (DMP) are typically available at >99% purity, ensuring consistent performance in specialized applications.
