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1-HEXADECANOL

CAS:    36653-82-4
MF:    C16H34O
MW:    242.44
EINECS:    253-149-0

1-hexadecanol, also known as Cetyl alcohol and palmityl alcohol, is a solid organic compound and a member of the alcohol class of compounds. 
1-hexadecanol's chemical formula is CH3(CH2)15OH. 
At room temperature, 1-hexadecanol takes the form of a waxy white solid or flakes. 
1-hexadecanol belongs to the group of fatty alcohols. 
With the demise of commercial whaling, 1-hexadecanol is no longer primarily produced from whale oil, but instead either as an end-product of the petroleum industry, or produced from vegetable oils such as palm oil and coconut oil. 
Production of 1-hexadecanol from palm oil gives rise to one of its alternative names, palmityl alcohol.
1-Hexadecanol has been used in preparation of:• (±)-2-methoxyheptadecanoic acid (fatty acid)• high-chain fatty acid esters of 1-hexadecanol, novel organic phase change material for thermal energy storage• hexadecane (alkane) in the presence of membrane fraction of Vibrio furnissii M1
1-hexadecanol is a white powder, granules, flakes or lumps; It has a fatty taste and is a transparent oily liquid after melting.
1-hexadecanol is miscible with ethanol and almost insoluble in water.
Soluble in alcohol, acetone, benzene, ether and chloroform, insoluble in water.
1-Hexadecanol, also known as Cetyl alcohol, is a fatty alcohol used as an opacifier in shampoos and as an emollient, emulsifier or thickening agent in skin creams. 
Ungraded products supplied by TCI America are generally suitable for common industrial uses or for research purposes but typically are not suitable for human consumption or therapeutic use.
1-hexadecanol is used in the cosmetic industry as an opacifier in shampoos, or as an emollient, emulsifier or thickening agent in the manufacture of skin creams and lotions. 
1-hexadecanol is also employed as a lubricant for nuts and bolts.
1-hexadecanol is used in the cosmetic industry as an opacifier in shampoos, or as an emollient, emulsifier or thickening agent in the manufacture of skin creams and lotions. 
1-hexadecanol is also employed as a lubricant for nuts and bolts.
Easily soluble in diethyl ether, soluble in acetone, chloroform; slightly soluble in alcohol.

1-Hexadecanol Chemical Properties
Melting point: 48-50 °C (lit.)
Boiling point: 179-181 °C/10 mmHg (lit.)
Density: 0.818 g/mL at 25 °C (lit.)
Vapor density: 8.34 (vs air)
Vapor pressure: <0.01 mm Hg ( 43 °C)
FEMA: 2554 | 1-HEXADECANOL
Refractive index: nD79 1.4283
Fp: 275 °F
Storage temp.: Store below +30°C.
Solubility: Soluble in alcohol, chloroform, ether
pka: 15.20±0.10(Predicted)
Form: Powder, Flakes or Pellets
Color: White to off-white
Explosive limit: 8%
Water Solubility: insoluble
JECFA Number: 114
Merck: 14,2028
BRN: 1748475
Stability: Stable. Incompatible with strong oxidizing agents, strong acids.
LogP: 6.7
CAS DataBase Reference: 36653-82-4(CAS DataBase Reference)
NIST Chemistry Reference: 1-Hexadecanol(36653-82-4)
EPA Substance Registry System: 1-Hexadecanol (36653-82-4)

Uses
Mainly 1-hexadecanol is used as an opacifier, emulsifier, and thickening agent that alter the thickness of the liquid, and increase and stabilize the foaming capacity. 
Due to 1-hexadecanol's water-binding property, cetyl alcohol is commonly used as an emollient that prevents drying and chapping of the skin.
1-Hexadecanol is often used to make other chemicals used in detergents, cleaners, to help make plastics, adhesives and to help change the thickness of liquid products.
1-Hexadecanol is also used directly in cosmetics and personal care products. 
1-hexadecanol is used as a skin softener and to help skin keep its moisture. 
1-hexadecanol helps keep oils and water mixed together and change the thickness of liquid products. 
1-Hexadecanol is used to turn creams an opaque color which protects the product from light. 
1-hexadecanol can also be used as a lubricant for nuts, bolts, washers, pins and other fasteners.
1-Hexadecanol has been tested in many toxicology studies. 
These studies show 1-Hexadecanol has a low toxicity when it is breathed in, swallowed, or touches the skin. 
The main hazard of 1-Hexdecanol is it can cause mild to moderate skin and eye irritation. 
The irritation is short lasting and will go away after you are no longer exposed. 
1-Hexadecanol does not cause damage to genes. 
1-Hexadecanol is easily broken down by the body. 
This prevents 1-Hexadecanol from building up in the body.
In personal care products like skin lotions and creams, 1-hexadecanol serves as a thickening agent and emulsifier, to help keep product ingredients from separating. 
Because 1-hexadecanol melts at temperatures higher than the average human body temperature, it is useful in cosmetic products like lipsticks, helping lip color adhere to the skin.
1-hexadecanol is also a multipurpose food additive, used as a flavoring agent or in food decorations. 
For example, 1-hexadecanol is an ingredient in colorful lettering or pictures on some types of candy or gum.
In industrial applications, 1-hexadecanol is a primary ingredient in fuels, chemical intermediates and plasticizers and is used as a lubricant for nuts and bolts in manufacturing applications.


Production Methods    
1-hexadecanol may be manufactured by a number of methods such as esterification and hydrogenolysis of fatty acids or by catalytic hydrogenation of the triglycerides obtained from coconut oil or tallow. 
1-hexadecanol may be purified by crystallization and distillation.

Synonyms    
Ethal
Ethol
Cetal
Cetanol
CO-1670
Cetylol
Atalco C
LorolL 24
Loxanol K
Cetaffine
DYTOL F-11
Hexadecanol
Product 308
Alcohol, C16
1-Hexadecanol
Cetyl Alcohol
Cachalot C-50
Hexadecan-1-ol
Palmityl alcohol
Hexadecyl alcohol
1-Hexadecanol
cetyl alcohol
Hexadecan-1-ol
36653-82-4
HEXADECANOL
Cetanol
Palmityl alcohol
Hexadecyl alcohol
N-Hexadecanol
n-1-Hexadecanol
n-Cetyl alcohol
Cetaffine
Cetylol
Cetal
Ethal
Ethol
Cetylic alcohol
n-Hexadecyl alcohol
Loxanwachs SK
Crodacol C
Loxanol K extra
1-Hexadecyl alcohol
Elfacos C
Loxanol K
Crodacol-CAS
Crodacol-CAT
Siponol wax-A
Atalco C
Cetalol CA
Siponol CC
Lanol C
1-Cetanol
Hyfatol 16
Cachalot C-50
Cachalot C-51
Cachalot C-52
Alcohol C-16
Product 308
Aldol 54
Dytol F-11
Adol
palmitic alcohol
Cyclal cetyl alcohol
Alfol 16
Lorol 24
Adol 52
Adol 54
Adol 52 NF
Hyfatol
Epal 16NF
1-Hexadecyl alc
16-Hexadecanol
C16 alcohol
Adol 520
n-Hexadecan-1-ol
Cetylalkohol
Isocetyl alcohol
1-Hexanedecanol
FEMA No. 2554
Isohexadecyl alcohol
cetylalcohol
SSD RP
Normal primary hexadecyl alcohol
CO-1670
CO-1695
Cetyl alchol
Lipocol C
Fancol CA
Cetyl alcohol NF
Crodacol C70
Rita CA
1-Hydroxyhexadecane
Cetanol (TN)
Lanette 16
Philcohol 1600
Cetyl alcohol (NF)
Cetyl alcohol [NF]
Lorol C16
LorolL 24
Cachalot C-50 NF
Adol 52NF
Alcohols, C14-18
NSC-4194
936JST6JCN
67762-30-5
CHEBI:16125
NSC4194
NCGC00159368-02
NCGC00159368-05
DSSTox_CID_7991
DSSTox_RID_78633
DSSTox_GSID_27991
Hexadecanol (VAN)
Fatty alcohol(C16)
Caswell No. 165D
FEMA Number 2554
Hexadecyl alcohol, normal
CAS-36653-82-4
HSDB 2643
NSC 4194
EINECS 253-149-0
UNII-936JST6JCN
EPA Pesticide Chemical Code 001508
Cetyl alcohol (hexadecanol)
BRN 1748475
hexadecylalcohol
AI3-00755
Hexadecanol NF
Alcohol cetylicus
Ceraphyl ICA
Crodacol C95NF
Dehydag wax 16
Eutanol G16
Crodacol C95 NF
Laurex 16
MFCD00004760
Alfol 16RD
SSD (Salt/Mix)
Cetanol (JP17)
Epal 16
Hyfatol 16-95
Kalcol 6098
Loxiol VPG 1743
1-Hexadecanol, 95%
SSD RP (Salt/Mix)
CETANOL [JAN]
bmse000487
CHEMBL706
Michel XO-150-16
EC 253-149-0
Fatty alcohols(c12-16)
1-Hexadecanol, >=99%
CETYL ALCOHOL [II]
CETYL ALCOHOL [MI]
SCHEMBL3381
CETYL ALCOHOL [HSDB]
CETYL ALCOHOL [INCI]
124-29-8
4-01-00-01876 (Beilstein Handbook Reference)
1-HEXADECANOL [FHFI]
CETYL ALCOHOL [VANDF]
CETYL ALCOHOL [MART.]
CETYL ALCOHOL [USP-RS]
CETYL ALCOHOL [WHO-DD]
CETYL ALCOHOL [WHO-IP]
DTXSID4027991
AMY6070
Cetyl alcohol, analytical standard
Cetyl alcohol, puriss., 95.0%
HMS3652H05
CS-D1348
HY-B1465
ZINC8214519
EINECS 252-964-9
Tox21_111609
Tox21_300325
CETYL ALCOHOL [EP MONOGRAPH]
LMFA05000061
s4173
STL283943
UNII-1800H64066
AKOS005287456
Tox21_111609_1
1-Hexadecanol, ReagentPlus(R), 99%
CCG-266894
DB09494
ALCOHOL CETYLICUS [WHO-IP LATIN]
NCGC00159368-03
NCGC00159368-04
NCGC00159368-06
NCGC00254286-01
BS-16666
Cetyl alcohol, puriss., >=99.0% (GC)
FT-0701357
FT-0707360
H0071
SW219201-1
Cetyl alcohol, SAJ special grade, >=98.0%
Cetyl alcohol, Selectophore(TM), >=99.0%
EN300-19351
1-Hexadecanol, Vetec(TM) reagent grade, 94%
C00823
D00099
AB01566915_01
Q161632
SR-01000944409
SR-01000944409-1
1800H64066
810F139F-C57E-4DF1-916A-A320AD0DAF4D
F0001-1047
Cetyl alcohol, European Pharmacopoeia (EP) Reference Standard
Cetyl alcohol, United States Pharmacopeia (USP) Reference Standard
Cetyl Alcohol, Pharmaceutical Secondary Standard; Certified Reference Material

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