1-hexadecanol, also known as Cetyl alcohol and palmityl alcohol, is a solid organic compound and a member of the alcohol class of compounds.
1-hexadecanol's chemical formula is CH3(CH2)15OH.
At room temperature, 1-hexadecanol takes the form of a waxy white solid or flakes.
1-hexadecanol belongs to the group of fatty alcohols.
CAS Number: 36653-82-4
EC Number: 253-149-0
IUPAC Name: Hexadecan-1-ol
Chemical Formula: C16H34O
Other names: Ethal, Ethol, Cetal, Cetanol, CO-1670, Cetylol, Atalco C, LorolL 24, Loxanol K, Cetaffine, DYTOL F-11, Hexadecanol, Product 308, Alcohol, C16, 1-Hexadecanol, Cetyl Alcohol, Cachalot C-50, Hexadecan-1-ol, Palmityl alcohol, Hexadecyl alcohol, 1-Hexadecanol, cetyl alcohol, Hexadecan-1-ol, 36653-82-4, HEXADECANOL, Cetanol, Palmityl alcohol, Hexadecyl alcohol, N-Hexadecanol, n-1-Hexadecanol, n-Cetyl alcohol, Cetaffine, Cetylol, Cetal, Ethal, Ethol, Cetylic alcohol, n-Hexadecyl alcohol, Loxanwachs SK, Crodacol C, Loxanol K extra, 1-Hexadecyl alcohol, Elfacos C, Loxanol K, Crodacol-CAS, Crodacol-CAT, Siponol wax-A, Atalco C, Cetalol CA, Siponol CC, Lanol C, 1-Cetanol, Hyfatol 16, Cachalot C-50, Cachalot C-51, Cachalot C-52, Alcohol C-16, Product 308, Aldol 54, Dytol F-11, Adol, palmitic alcohol, Cyclal cetyl alcohol, Alfol 16, Lorol 24, Adol 52, Adol 54, Adol 52 NF, Hyfatol, Epal 16NF, 1-Hexadecyl alc, 16-Hexadecanol, C16 alcohol, Adol 520, n-Hexadecan-1-ol, Cetylalkohol, Isocetyl alcohol, 1-Hexanedecanol, FEMA No. 2554, Isohexadecyl alcohol, cetylalcohol, SSD RP, Normal primary hexadecyl alcohol, CO-1670, CO-1695, Cetyl alchol, Lipocol C, Fancol CA, Cetyl alcohol NF, Crodacol C70, Rita CA, 1-Hydroxyhexadecane, Cetanol (TN), Lanette 16, Philcohol 1600, Cetyl alcohol (NF), Cetyl alcohol [NF], Lorol C16, LorolL 24, Cachalot C-50 NF, Adol 52NF, Alcohols, C14-18, NSC-4194, 936JST6JCN, 67762-30-5, CHEBI:16125, NSC4194, NCGC00159368-02, NCGC00159368-05, DSSTox_CID_7991, DSSTox_RID_78633, DSSTox_GSID_27991, Hexadecanol (VAN), Fatty alcohol(C16), Caswell No. 165D, FEMA Number 2554, Hexadecyl alcohol, normal, CAS-36653-82-4, HSDB 2643, NSC 4194, EINECS 253-149-0, UNII-936JST6JCN, EPA Pesticide Chemical Code 001508, Cetyl alcohol (hexadecanol), BRN 1748475, hexadecylalcohol, AI3-00755, Hexadecanol NF, Alcohol cetylicus, Ceraphyl ICA, Crodacol C95NF, Dehydag wax 16, Eutanol G16, Crodacol C95 NF, Laurex 16, MFCD00004760, Alfol 16RD, SSD (Salt/Mix), Cetanol (JP17), Epal 16, Hyfatol 16-95, Kalcol 6098, Loxiol VPG 1743, 1-Hexadecanol, 95%, SSD RP (Salt/Mix), CETANOL [JAN], bmse000487, CHEMBL706, Michel XO-150-16, EC 253-149-0, Fatty alcohols(c12-16), 1-Hexadecanol, >=99%, CETYL ALCOHOL [II], CETYL ALCOHOL [MI], SCHEMBL3381, CETYL ALCOHOL [HSDB], CETYL ALCOHOL [INCI], 124-29-8, 4-01-00-01876 (Beilstein Handbook Reference), 1-HEXADECANOL [FHFI], CETYL ALCOHOL [VANDF], CETYL ALCOHOL [MART.], CETYL ALCOHOL [USP-RS], CETYL ALCOHOL [WHO-DD], CETYL ALCOHOL [WHO-IP], DTXSID4027991, AMY6070, Cetyl alcohol, analytical standard, Cetyl alcohol, puriss., 95.0%, HMS3652H05, CS-D1348, HY-B1465, ZINC8214519, EINECS 252-964-9, Tox21_111609, Tox21_300325, CETYL ALCOHOL [EP MONOGRAPH], LMFA05000061, s4173, STL283943, UNII-1800H64066, AKOS005287456, Tox21_111609_1, 1-Hexadecanol, ReagentPlus(R), 99%, CCG-266894, DB09494, ALCOHOL CETYLICUS [WHO-IP LATIN], NCGC00159368-03, NCGC00159368-04, NCGC00159368-06, NCGC00254286-01, BS-16666, Cetyl alcohol, puriss., >=99.0% (GC), FT-0701357, FT-0707360, H0071, SW219201-1, Cetyl alcohol, SAJ special grade, >=98.0%, Cetyl alcohol, Selectophore(TM), >=99.0%, EN300-19351, 1-Hexadecanol, Vetec(TM) reagent grade, 94%, C00823, D00099, AB01566915_01, Q161632, SR-01000944409, SR-01000944409-1, 1800H64066, 810F139F-C57E-4DF1-916A-A320AD0DAF4D, F0001-1047, Cetyl alcohol, European Pharmacopoeia (EP) Reference Standard, Cetyl alcohol
With the demise of commercial whaling, 1-hexadecanol is no longer primarily produced from whale oil, but instead either as an end-product of the petroleum industry, or produced from vegetable oils such as palm oil and coconut oil.
Production of 1-hexadecanol from palm oil gives rise to one of its alternative names, palmityl alcohol.
1-Hexadecanol has been used in preparation of:• (±)-2-methoxyheptadecanoic acid (fatty acid)• high-chain fatty acid esters of 1-hexadecanol, novel organic phase change material for thermal energy storage• hexadecane (alkane) in the presence of membrane fraction of Vibrio furnissii M1
1-hexadecanol is a white powder, granules, flakes or lumps; It has a fatty taste and is a transparent oily liquid after melting.
1-hexadecanol is miscible with ethanol and almost insoluble in water.
Soluble in alcohol, acetone, benzene, ether and chloroform, insoluble in water.
1-Hexadecanol, also known as Cetyl alcohol, is a fatty alcohol used as an opacifier in shampoos and as an emollient, emulsifier or thickening agent in skin creams.
Ungraded products supplied by TCI America are generally suitable for common industrial uses or for research purposes but typically are not suitable for human consumption or therapeutic use.
1-hexadecanol is used in the cosmetic industry as an opacifier in shampoos, or as an emollient, emulsifier or thickening agent in the manufacture of skin creams and lotions.
1-hexadecanol is also employed as a lubricant for nuts and bolts.
1-hexadecanol is used in the cosmetic industry as an opacifier in shampoos, or as an emollient, emulsifier or thickening agent in the manufacture of skin creams and lotions.
1-hexadecanol is also employed as a lubricant for nuts and bolts.
Easily soluble in diethyl ether, soluble in acetone, chloroform; slightly soluble in alcohol.
1-Hexadecanol Chemical Properties
Melting point: 48-50 °C (lit.)
Boiling point: 179-181 °C/10 mmHg (lit.)
Density: 0.818 g/mL at 25 °C (lit.)
Vapor density: 8.34 (vs air)
Vapor pressure: <0.01 mm Hg ( 43 °C)
Uses
Mainly 1-hexadecanol is used as an opacifier, emulsifier, and thickening agent that alter the thickness of the liquid, and increase and stabilize the foaming capacity.
Due to 1-hexadecanol's water-binding property, cetyl alcohol is commonly used as an emollient that prevents drying and chapping of the skin.
1-Hexadecanol is often used to make other chemicals used in detergents, cleaners, to help make plastics, adhesives and to help change the thickness of liquid products.
1-Hexadecanol is also used directly in cosmetics and personal care products.
1-hexadecanol is used as a skin softener and to help skin keep its moisture.
1-hexadecanol helps keep oils and water mixed together and change the thickness of liquid products.
1-Hexadecanol is used to turn creams an opaque color which protects the product from light.
1-hexadecanol can also be used as a lubricant for nuts, bolts, washers, pins and other fasteners.
1-Hexadecanol has been tested in many toxicology studies.
These studies show 1-Hexadecanol has a low toxicity when it is breathed in, swallowed, or touches the skin.
The main hazard of 1-Hexdecanol is it can cause mild to moderate skin and eye irritation.
The irritation is short lasting and will go away after you are no longer exposed.
1-Hexadecanol does not cause damage to genes.
1-Hexadecanol is easily broken down by the body.
This prevents 1-Hexadecanol from building up in the body.
In personal care products like skin lotions and creams, 1-hexadecanol serves as a thickening agent and emulsifier, to help keep product ingredients from separating.
Because 1-hexadecanol melts at temperatures higher than the average human body temperature, it is useful in cosmetic products like lipsticks, helping lip color adhere to the skin.
1-hexadecanol is also a multipurpose food additive, used as a flavoring agent or in food decorations.
For example, 1-hexadecanol is an ingredient in colorful lettering or pictures on some types of candy or gum.
In industrial applications, 1-hexadecanol is a primary ingredient in fuels, chemical intermediates and plasticizers and is used as a lubricant for nuts and bolts in manufacturing applications.
Production Methods
1-hexadecanol may be manufactured by a number of methods such as esterification and hydrogenolysis of fatty acids or by catalytic hydrogenation of the triglycerides obtained from coconut oil or tallow.
1-hexadecanol may be purified by crystallization and distillation.