PRODUCTS

1-HYDROXYETHYLIDENE-1,1-DIPHOSPHONIC ACID

1-Hydroxyethylidene-1,1-diphosphonic acid is non-nitrogenous bisphosphonate.
1-Hydroxyethylidene-1,1-diphosphonic acid was patented in 1966 and approved for medical use in 1977.
For medicinal purposes, 1-Hydroxyethylidene-1,1-diphosphonic acid acid has been obsolete since the early 2010's.
1-Hydroxyethylidene-1,1-diphosphonic acid with its CAS number 2809-21-4 is a cost effective scale inhibitor used in various industrial applications such as industrial water treatment and detergents.

CAS Number: 2809-21-4
EC Number: 220-552-8
IUPAC Name: (1-Hydroxyethan-1,1-diyl)bis(phosphonic acid)
Chemical Formula: C2H8O7P2

Other names: HEDP, EHDP, Etidronsaeure, Acetodiphosphonic acid, Hydroxyethanediphosphonic acid, Turpinal SL, Acido etidronico, Oxyethylidenediphosphonic acid, Acide etidronique, Dequest 2015, Dequest Z 010, Phosphonic acid, (1-hydroxyethylidene)bis-, Ferrofos 510, 1-Hydroxyethane-1,1-diphosphonic acid, Diphosphonate (base), Dequest 2010, 1-Hydroxyethanediphosphonic acid, (1-Hydroxyethylidene)diphosphonic acid, 1-Hydroxyethane-1,1-bisphosphonic acid, (Hydroxyethylidene)diphosphonic acid, Ethane-1-hydroxy-1,1-diphosphonic acid, (1-Hydroxyethylene)diphosphonic acid, Acidum etidronicum, 1-HYDROXY-1,1-DIPHOSPHONOETHANE, (1-Hydroxyethylidene)bis(phosphonic acid), (1-Hydroxyethylidene)bisphosphonic acid, Hydroxyethane-1,1-diphosphonic acid, (1-hydroxyethane-1,1-diyl)bis(phosphonic acid), 1000SL, (1-Hydroxyethylidene)diphoshonic acid, RP 61, HSDB 5898, Phosphonic acid, (1-hydroxyethylidene)di-, UNII-M2F465ROXU, EINECS 220-552-8, M2F465ROXU, NSC 227995, NSC-227995, BRN 1789291, OEDP, Phosphonic acid, 1-hydroxy-1,1-ethanediyl ester, CHEBI:4907, ethane-1-hydroxy-1,1-bisphosphonic acid, DTXSID6023028, M05BA01, 1-hydroxyethane 1,1-diphosphonic acid, (1-hydroxy-ethylidene)diphosphonic acid, DTXCID103028, EC 220-552-8, 0-02-00-00171 (Beilstein Handbook Reference), NSC227995, hydroxyethylidene-1,1-diphosphonic acid, ETIDRONIC ACID (MART.), ETIDRONIC ACID [MART.], Etidronsaure, Diphosphonic Acid, Hydroxyethylidene, V10BX03, 220-552-8, hydroxyethylidene diphosphonic acid, 2809-21-4, etidronate, 1-Hydroxyethane-1,1-diphosphonate, (1-Hydroxyethane-1,1-diyl)diphosphonic acid, Ethane-1-hydroxy-1,1-diphosphonate, Acide etidronique [INN-French], Acido etidronico [INN-Spanish], Acidum etidronicum [INN-Latin], 1,1,1-Ethanetriol diphosphonate, 1-Hydroxyethylidene-1,1-bisphosphonate, (1-hydroxy-1-phosphonoethyl)phosphonic acid, MFCD00070585, Etidronic Acid-d3, (1-hydroxy-1-phosphono-ethyl)phosphonic acid, CHEMBL871, 2809-21-4 (freeacid), Etidronic Acid-d3 Sodium Salt, Phosphonic acid, P,P'-(1-hydroxyethylidene)bis-, (1-hydroxyethan-1,1-diyl)bis(phosphonic acid), Etidronic acid [USAN:INN:BAN], SMR000038750, 1-Hydroxyethylidene-1,1-biphosphonate, C2H8O7P2, 358730-93-5, 1-Hydroxyethylidenediphosphonic acid, NCGC00159352-02, Etidronicacid, Etidronic acid (USAN/INN), etidronic-acid, Ethane-1-hydroxy-1,1-bisphosphonate, Etidronic acid;HEDP, HDEPA, OEDFK, Etidronate (Didronel), 1-HydroxyEthylidene-1,1-DiphosphonicAcid, Prestwick0_000863, Prestwick1_000863, Prestwick2_000863, Prestwick3_000863, ETIDRONATE [VANDF], (1-Hydroxy-1,1-ethanediyl)bis(phosphonic acid), ETIDRONIC ACID [MI], SCHEMBL18607, BSPBio_000905, ETIDRONIC ACID [INN], MLS002207267, MLS002695948, ETIDRONIC ACID [HSDB], ETIDRONIC ACID [USAN], SPBio_002826, BPBio1_000997, GTPL7184, ETIDRONIC ACID [WHO-DD], Etidronic acid monohydrate (HEDP), HMS3604E03, HY-B0302, Tox21_200417, BBL028139, BDBM50115102, DL-390, s1857, STK721995, AKOS005524039, CCG-266618, DB01077, FH15419, s12329, NCGC00159352-04, NCGC00159352-05, NCGC00159352-06, NCGC00159352-14, NCGC00257971-01, CAS-2809-21-4, 1,1-Ethylidenediphosphonic acid, 1-hydroxy-, H0587, NS00006820, (1-Hydroxy-1-phosphono-ethyl)-phosphonic acid, A23202, C07736, D02373, Q2758338, BRD-K37949327-001-06-3, BRD-K37949327-001-07-1, BRD-K37949327-304-06-1, (1-Hydroxyethane-1,1-diyl)diphosphonic acid monohydrate, Z1269201561, (1-Hydroxyethylidene)bisphosphonic acid 60% aqueous solution, 1-Hydroxyethane-1,1-diphosphonic acid (ca. 60% in Water, ca. 4.2mol/L), 1-Hydroxyethylidene-1,1-diphosphonic acid - 60% aqueous solution,~4.2mol/L

Additionally 1-Hydroxyethylidene-1,1-diphosphonic acid shows a good stability in presence of chlorine as well as corrosion inhibition properties in presence of zinc and other phosphates and can also be used as chelating agent in the textile industry.
1-Hydroxy Ethylidene-1,1-Diphosphonic Acid is an organophosphoric acid corrosion inhibitor.
1-Hydroxyethylidene-1,1-diphosphonic acid can chelate with Fe, Cu, and Zn ions to form stable chelating compounds.

1-Hydroxyethylidene-1,1-diphosphonic acid can dissolve the oxidized materials on these metals’ surfaces.
1-Hydroxy Ethylidene-1,1-Diphosphonic Acid shows excellent scale and corrosion inhibition effects under temperature 250℃.
1-Hydroxy Ethylidene-1,1-Diphosphonic Acid has good chemical stability under high pH value, hard to be hydrolyzed, and hard to be decomposed under ordinary light and heat conditions.

1-Hydroxyethylidene-1,1-diphosphonic acid acid/alkali and chlorine oxidation tolerance are better than that of other organophosphoric acids (salt).
1-Hydroxyethylidene-1,1-diphosphonic acid can react with metal ions in water system to form hexa-element chelating complex, with calcium ion in particular.
Therefore, HEDP has good antiscale and visible threshold effects.
When built together with other water treatment chemicals, it shows good synergistic effects.

The solid state of 1-Hydroxyethylidene-1,1-diphosphonic acid is crystal powder, suitable for usage in winter and freezing districts.
Because of its high purity, it can be used as cleaning agent in electronic fields and as additives in daily chemicals.

1-Hydroxyethylidene-1,1-diphosphonic acid is a kind of scale and corrosion inhibitor which belongs to organic phosphonic acid.
1-Hydroxyethylidene-1,1-diphosphonic acid can form stable complexes with iron, copper, zinc and other metal ions, and can also dissolve the metal surface oxide.
Under 250 ℃ condition, 1-Hydroxy Ethylidene-1,1-Diphosphonic Acid can still play a good corrosion and scale inhibition effect.

1-Hydroxyethylidene-1,1-diphosphonic acid can react with metal ions in water system to form hexa-element chelating complex, especially with calcium ions.
Therefore, 1-Hydroxy Ethylidene-1,1-Diphosphonic Acid has good anti-scale and visible threshold effects.
When used in combination with other water treatment chemicals, it shows ideal synergistic effects.

1-Hydroxyethylidene-1,1-diphosphonic acid solid state is a high purity product, suitable for cold winter areas;
Because of its high purity, it is especially used as the cleaning agents in electronics industry, and additives in daily chemicals.

colorless to light yellow viscous liquid. The pure product is a colorless, amorphous Crystal, miscible with water.
Soluble in water, methanol, ethanol.
1-Hydroxyethylidene-1,1-diphosphonic acid has a large dissociation constant in water and can form stable chelates and complexes with metal ions.

1-Hydroxyethylidene-1,1-diphosphonic acid can form a stable adduct with a compound containing active oxygen, and keep the active oxygen stable.
Chlorine resistance is good.
Industrial product content is generally 50% ~ 62% colorless to light yellow viscous transparent aqueous solution, is a kind of Polybasic acid, soluble in water.

1-Hydroxyethylidene-1,1-diphosphonic acid is an important chelating agent, which is stable with several metal ions and is not easy to hydrolyze.
1-Hydroxyethylidene-1,1-diphosphonic acid is not decomposed under General light and heat conditions, but is not resistant to the action of oxidative biocide.
About 30% of HEDP with 5mg/L of residual chlorine is decomposed.

1-Hydroxyethylidene-1,1-diphosphonic acid is an organophosphoric acid corrosion inhibitor.
1-Hydroxyethylidene-1,1-diphosphonic acid can chelate with Fe, Cu, and Zn etc. metal ions and form stable complex compound.
1-Hydroxyethylidene-1,1-diphosphonic acid can dissolve the oxidized materials on these metals'surfaces.

1-Hydroxyethylidene-1,1-diphosphonic acid shows excellent scale and corrosion inhibition ability.
1-Hydroxyethylidene-1,1-diphosphonic acid has good chemical stability under high pH value, hard to be hydrolyzed, and hard to be decomposed under ordinary light and heat conditions.
1-Hydroxyethylidene-1,1-diphosphonic acid acid/alkali and chlorine oxidation tolerance are better than that of other organophosphoric acids (salt).
1-Hydroxyethylidene-1,1-diphosphonic acid can react with metal ions in water system to form hexa-element chelating complex, with calcium ion in particular.

Therefore, 1-Hydroxyethylidene-1,1-diphosphonic acid has good antiscale and visible threshold effects.
When built together with other water treatment chemicals, it shows good synergistic effects.
The solid of 1-Hydroxyethylidene-1,1-diphosphonic acid is high purity product, suitable for using in winter and freezing districts.
1-Hydroxyethylidene-1,1-diphosphonic acid is quite suitable for using as cleaning agent in electronic fields and as additives in daily chemicals.

1-Hydroxyethylidene-1,1-diphosphonic acid is used as scale and corrosion inhibition in circulating cool water system, oil field and low-pressure boilers in fields such as electric power, chemical industry, metallurgy, fertilizer, etc..
In light woven industry, 1-Hydroxyethylidene-1,1-diphosphonic acid is used as detergent for metal and nonmetal.

In dyeing industry, 1-Hydroxyethylidene-1,1-diphosphonic acid is used as peroxide stabilizer and dye-fixing agent;
In non-cyanide electroplating, HEDP is used as chelating agent.
The dosage of 1-10mg/L is preferred as scale inhibitor, 10-50mg/L as corrosion inhibitor, and 1000-2000mg/L as detergent.
Usually, 1-Hydroxyethylidene-1,1-diphosphonic acid is used together with polycarboxylic acid.

1-Hydroxyethylidene-1,1-diphosphonic acid is an organic phosphonic acid corrosion inhibitor, can dissociate into five positive and negative ions in the water, can chelate Divalent metal ions in the water, and iron, copper, aluminum, zinc and other metal ions forming a stable complex, has a good scale effect.

Melting point:198~199℃
Boiling point:578.8±60.0 °C(Predicted)
Density 1.45 (60% aq.)
storage temp. Sealed in dry,Room Temperature
form Powder
pka1.35, 2.87, 7.03, 11.3(at 25℃)
color white
PHpH (1.7→100, 25℃) : 1.3～1.8
Water Solubility Soluble in water.
Merck 14,3863
BRN 1789291

1-Hydroxyethylidene-1,1-diphosphonic acid is widely used as scale and corrosion inhibitor in industrial circulating cooling water systems of electric power, chemical industry, metallurgy, chemical fertilizer, and also in medium or low pressure boilers, oilfield water injection and oil pipeline.

Besides these applications, 1-Hydroxy Ethylidene-1,1-Diphosphonic Acid can also be used as cleaning agent of metal and nonmetal in the textile industry, as peroxide stabilizer and fixing agent in bleaching and dyeing industry, as complexing agent in cyanide free electroplating industry, as the carrier of radioactive elements in pharmaceutical industry, and so on.

1-Hydroxyethylidene-1,1-diphosphonic acid is an organophosphoric acid corrosion inhibitor.
1-Hydroxyethylidene-1,1-diphosphonic acid 1-Hydroxyethylidene-1,1-diphosphonic acidP can chelate with Fe, Cu, and Zn ions to form stable chelating compounds.
1-Hydroxyethylidene-1,1-diphosphonic acid can dissolve the oxidized materials on these metals' surfaces.
1-Hydroxyethylidene-1,1-diphosphonic acid shows excellent scale and corrosion inhibition effects under temperature250.

1-Hydroxyethylidene-1,1-diphosphonic acid has good chemical stability under high pH value, hard to be hydrolyzed, and hard to be decomposed under ordinary light and heat conditions.
1-Hydroxyethylidene-1,1-diphosphonic acid acid/alkali and chlorine oxidation tolerance are better than that of other organophosphoric acids (salt)HEDP is used as scale and corrosion inhibition in circulating cool wateroil fieland low-pressure boilers in fields such as electric power, chemical industry, metallurgy, fertilizer, etc

Cooling water systems / industrial water treatment
Industrial detergents
Swimming pools
Metal surface treatment as a corrosion inhibitor for steel
Stabilizer in H2O2 solutions
Sequestering agent in textile auxiliaries

1-Hydroxyethylidene-1,1-diphosphonic acid is used with metal deionization in textile.
1-Hydroxyethylidene-1,1-diphosphonic acid is used in the processes of cleaning and stain removal.
1-Hydroxyethylidene-1,1-diphosphonic acid is used in the fields of pool chemicals and water conditioning.

1-Hydroxyethylidene-1,1-diphosphonic acid is used as scale and corrosion inhibition in circulating cool water system, oil field and low-pressure boilers in fields such as electric power, chemical industry, metallurgy, fertilizer, etc.. In light woven industry, 1-Hydroxy Ethylidene-1,1-Diphosphonic Acid is used as detergent for metal and nonmetal.

In dyeing industry, 1-Hydroxy Ethylidene-1,1-Diphosphonic Acid is used as peroxide stabilizer and dye-fixing agent;
In non-cyanide electroplating, 1-Hydroxyethylidene-1,1-diphosphonic acid is used as chelating agent.
The dosage of 1-10mg/L is preferred as scale inhibitor, 10-50mg/L as corrosion inhibitor, and 1000-2000mg/L as detergent.
Usually, 1-Hydroxyethylidene-1,1-diphosphonic acid is used together with polycarboxylic acid.

The effectiveness of 1-Hydroxyethylidene-1,1-diphosphonic acid as a corrosion inhibitor was investigated by measuring corrosion weight losses and polarization curves of SS 41 steel in 0.3% NaCl. In concentrations lower than 50 ppm of 1-Hydroxyethylidene-1,1-diphosphonic acid, the corrosion of SS 41 steel was inhibited in accordance with the Langmuir adsorption isotherm of 1-Hydroxyethylidene-1,1-diphosphonic acid on the steel.
The adsorption was believed to be a chemical adsorption resulting from the value of adsorption heat.

In concentrations greater than 50 ppm of 1-Hydroxyethylidene-1,1-diphosphonic acid, the iron complex of HEDP developed, and the inhibition effect was decreased.
Instead, it caused rust to be removed from the steel surface.
The mutual inhibition effect by adding both 1-Hydroxyethylidene-1,1-diphosphonic acid and the Zn2+ ion in 0.3% NaCl solution was progressively more increased.