PRODUCTS

1-METHOXY-2-PROPANOL

1-METHOXY-2-PROPANOL = PROPYLENE GLYCOL METHYL ETHER

CAS Number: 107-98-2
EC Number: 203-539-1
MDL number: MFCD00004537
Linear Formula: CH3CH(OH)CH2OCH3 / C4H10O2

1-methoxy-2-propanol (Propylene glycol methyl ether or PGME) is an organic solvent with a wide variety of industrial and commercial uses.
1-methoxy-2-propanol appears as a colorless liquid.
Flash point near 89°F.

Less dense than water.
Vapors heavier than air.
1-methoxy-2-propanol (also known as propylene glycol monomethyl ether, PM, and PGME), is a colourless liquid that is soluble in water.

1-methoxy-2-propanol is a methoxy alcohol derivative and has a formula of C4H10O2.
1-Methoxy-2-propanol is a glycol ether and a good biological indicator of exposure.
1-Methoxy-2-propanol (Propylene glycol methyl ether, PGME), a glycol ether, can be synthesized by reacting propylene oxide with methanol in the presence of ZnMgAl (zinc-magnesium-aluminium) catalysts.

1-methoxy-2-propanol is an organic compound that has no color, no odor, is a transparent viscous liquid and has a lightly sweet tatse.
1-methoxy-2-propanol is miscible and hygroscopic with water, acetone and chloroform.
1-methoxy-2-propanol is the fastest evaporating solvent of the glycol ether family.

1-methoxy-2-propanol is registered under the REACH Regulation and is manufactured in and / or imported to the European Economic Area, at ≥ 100 000 to < 1 000 000 tonnes per annum.
1-methoxy-2-propanol has a high water solubility, excellent solvent with good coupling properties making 1-methoxy-2-propanol suitable for cleaning solutions and coating applications.

1-methoxy-2-propanol, This hydrophilic solvent has 100% water solubility and is ideally suited as a coupling agent in a wide range of solvent systems.
1-Methoxy 2-propanol, 98% - is an organic solvent with a wide variety of industrial and commercial uses.
1-methoxy-2-propanol is a color- less liquid.

Ethereal odor.
The Odor Threshold is 10 ppm.
1-methoxy-2-propanol is a colorless liquid with a sweet ether-like odor and bitter taste.
1-methoxy-2-propanol is soluble in water, ether, acetone, and benzene.

1-methoxy-2-propanol, also known as propylene glycol methyl ether, is a clear, colourless liquid with a faint ether-like odour.
1-methoxy-2-propanol is soluble in water and has moderate volatility.
Methoxy propanol is a propylene oxide-based glycol ether which is fast evaporating and hydrophilic.

1-methoxy-2-propanol has low surface tension as well as excellent solvency and coupling abilities.
1-methoxy-2-propanol is a clear, hygroscopic, medium-volatility liquid with a mild, alcoholic odor.
1-methoxy-2-propanol is miscible with water and many common organic solvents.

By virtue of 1-methoxy-2-propanol's ether and alcohol groups, 1-methoxy-2-propanol has very good solvent power for many of the raw materials used in coatings, e. g. resins, binders, etc.
1-methoxy-2-propanol possesses the typical properties of the ether and alcohol groups.

For instance, 1-methoxy-2-propanol may react with acids (or form esters), oxidizing agents (to form the corresponding ketones or carboxylic acids), alkali metals (to form alcoholates) or aldehydes (to form acetals).
1-methoxy-2-propanol may form peroxides with atmospheric oxygen.

Colorless, medium-volatility, water-miscible neutral liquid with a mild, alcoholic odour.
1-methoxy-2-propanol's favourable physiological properties make 1-methoxy-2-propanol preferable to methoxyethanol and ethoxyethanol as a solvent for coatings and printing inks.

USES and APPLICATIONS of 1-METHOXY-2-PROPANOL:
-Cosmetic Uses:
perfuming agents
solvents

-Similar to other glycol ethers, 1-methoxy-2-propanol is used as a carrier/solvent in printing/writing inks and paints/coatings.
-1-methoxy-2-propanol also finds use as an industrial and commercial paint stripper.

-1-methoxy-2-propanol is used as an antifreeze in diesel engines.
-1-methoxy-2-propanol is used as a solvent and as an antifreeze agent.
-1-methoxy-2-propanol is also used as a cleaning agent in the LCD and electronics industry.

-1-methoxy-2-propanol is predominately used in the manufacture of propylene glycol methyl ether acetate (otherwise known as PMA) and is also used in industrial and commercial products including paints, varnishes, inks, synthetic resin and rubber adhesives, and automotive and oven cleaners.

-Nearly half of all propylene glycol made is used for the fabrication of unsaturated polyester resin.
-1-methoxy-2-propanol is also used in food and tabacco products as a humectant, preservative and solvent.
-1-methoxy-2-propanol is used by consumers, in articles, by professional workers (widespread uses), in formulation or re-packing, at industrial sites and in manufacturing.

-1-methoxy-2-propanol is used in the following products: coating products, washing & cleaning products, anti-freeze products and cosmetics and personal care products.
-Active solvent for solvent-based coatings.
-Active and tail solvent for solvent based gravure and flexographic printing inks.

-Other release to the environment of 1-methoxy-2-propanol is likely to occur from: indoor use (e.g. machine wash liquids/detergents, automotive care products, paints and coating or adhesives, fragrances and air fresheners) and outdoor use as processing aid.

-Coupling agent in solvent blends for water-based gravure, flexographic, and silk screen printing inks.
-Carrier solvent for ball point and felt tip writing pen inks.
-Coupling agent and solvent for household and industrial cleaners, rust removers, and hard surface cleaners.
-Solvent for agricultural pesticides, deactivator and emollient for livestock pesticides

-1-Methoxy 2-propanol, 99% Cas no 107-98-2 - is used as a reagent in the synthesis of 2-amino-3-carboxy-4-phenylthiophenes, which acts as a protein kinase C inhibitors.
-1-Methoxy 2-propanol, 99% Cas no 107-98-2 - used as a reagent in the synthesis of metolachlor.
-1-methoxy-2-propanol acts as a good biological indicator.

-1-methoxy-2-propanol is primarily used in the manufacture of lacquers and paints, as an anti-freeze in industrial engines, a tailing agent for inks used on very high-speed presses, a coupling agent for resins and dyes in waterbased inks, and a solvent for celluloses, acrylics, dyes, inks, and stains.

-1-methoxy-2-propanol is also used in cleaning products such as glass and rug cleaners, carbon and grease removers, and paint and varnish removers; and in pesticide formulations as a solvent for applications to crops and animals.
-1-methoxy-2-propanol is used as a solvent for cellulose, acrylics, dyes, inks, and cellophane.

-1-Methoxy-2-propanol is used as a reagent in the synthesis of 2-amino-3-carboxy-4-phenylthiophenes, which acts as a protein kinase C inhibitors.
-1-Methoxy-2-propanol is mainly used as solvent, dispersant and diluent, as well as fuel antifreeze, extractant, etc.
-1-methoxy-2-propanol is used as solvent of nitrocellulose, compounding agent of brake oil and detergent, etc.

-1-methoxy-2-propanol is also used as a reagent in the synthesis of metolachlor.
1-methoxy-2-propanol acts as a good biological indicator.
Further, 1-methoxy-2-propanol is used as a solvent and an antifreeze agent.

-1-methoxy-2-propanol is widely used in coatings and cleaners.
-A glycol ether and a good biological indicator of exposure.
-1-methoxy-2-propanol is primarily used as a chemical building block for the production of propylene glycol methyl ether acetate.

-1-methoxy-2-propanol can be used as the active solvent of water-based coatings; Active solvent and coupling agent of solvent based printing ink; Solvent for ballpoint pens and pens; Coupling agents and solvents for household and industrial cleaners, derusting agents and hard surface cleaners; Solvents for agricultural pesticides; Mixed with propylene glycol n-butyl ether for glass cleaner formula.

-1-methoxy-2-propanol is also used as a solvent in manufacturing processes for the chemical, automotive and agricultural industries and in paint, lacquer and varnishes.
-1-methoxy-2-propanol is used as a coalescing agent in water-based paints and inks where 1-methoxy-2-propanol promotes polymer fusion during the drying process.

-1-methoxy-2-propanol is formulated into a wide range of cleaners for industrial and commercial use such as those for ovens, glass, hard surfaces, floors, carpets and upholstery, as well as in speciality sanitation products such as swimming pool cleaners.
-1-methoxy-2-propanol is also present in many everyday products such as polish, laundry aids, caulk, sealants, pesticides, inks for ballpoint and felt-tip pens, synthetic resin and rubber adhesives.

-Solvent for cellulose, acrylics, dyes, inks, and stains; lacquers and paints
-1-methoxy-2-propanol possesses properties similar to those of methoxyethanol and ethoxyethanol and used in the same applications, particularly in coatings and printing inks.

-Printing inks:
1-methoxy-2-propanol is eminently suitable for use in printing inks, e.g. for cellulose nitrate flexographic inks.
1-methoxy-2-propanol can also be used in gravure inks.
1-methoxy-2-propanol regulates, i. e. retards, the drying of printing inks, but two facts should be noted in this respect.

1-methoxy-2-propanol (evaporation rate= 22; ether = 1) dries more rapidly than ethoxyethanol (evaporation rate = 43).
In other words, somewhat greater amounts are required to retard drying.
A general rule is that drying regulators incur the risk of solvent retention and blocking if their proportion is too high or
if inadequate time is allowed for drying.
This also applies to 1-methoxy-2-propanol.
1-methoxy-2-propanol can also be used for cleaning printing plates and for thinning printing inks.

-Coatings Industry:
The main application for 1-methoxy-2-propanol in the coatings industry is the production of cellulose nitrate lacquers.
The initial solutions can be thinned with many cheap diluents, yet still dry to give clear, transparent coatings of good strength.

1-methoxy-2-propanol improves the brushability, levelling and gloss of air drying paints and prevents blushing.
1-methoxy-2-propanol is included in formulations for paints applied by a spray-gun for the purpose of improving gloss and adhesion.

-Component in copying fluids (particularly together with alcohols, inks, and felt-tip pen inks)
-Component in the solvent phase for road marking paints
-Solvent or leather finishes and stamp pad inks

-Additive in cleaners, e. g. for metals, windows and floors
-Component in the solvent phase for wood stains and polishes
-Starting material in the production of Methoxypropyl Acetate, which is also an excellent solvent

-Component in liquids for the evaporative cooling of engines, particularly large diesel engines.
-Starting material in the production of esters that may be used as plasticizers.
-Excellent solvent for nitrocellulose, alkyd resin and maleic anhydride modified phenolic resin

-1-methoxy-2-propanol is used as an additive for jet fuel antifreeze and brake fluid
-1-methoxy-2-propanol is used as a solvent, dispersant and diluent, also as a fuel antifreeze, extractant
-1-methoxy-2-propanol is used in coatings, inks, printing and dyeing, pesticides, cellulose, acrylates, etc.

HOW IS 1-METHOXY-2-PROPANOL PRODUCED?
1-methoxy-2-propanol is produced by the reaction of 1,2-epoxy propane and methanol in the presence of a catalyst, and this is then followed by distillation.
The worldwide annual production of 1-methoxy-2-propanol is approximately 100,000 to 500,000 tonnes.

REACTIVITY PROFILE of 1-METHOXY-2-PROPANOL:
1-methoxy-2-propanol is a methoxy alcohol derivative.
The ether being relatively unreactive.
They react with oxoacids and carboxylic acids to form esters plus water.

Oxidizing agents convert them to aldehydes or ketones.
Alcohols exhibit both weak acid and weak base behavior.
They may initiate the polymerization of isocyanates and epoxides.

PHYSICAL and CHEMICAL PROPERTIES of 1-METHOXY-2-PROPANOL:
Molecular Weight: 90.12
Appearance Form: liquid, clear
Color: colorless
Odor: ethanolic
Odor Threshold: No data available
pH: No data available
Melting point/freezing point:
Melting point: -96 °C at 1.013 hPa - (ECHA)
Initial boiling point and boiling range: 118 - 119 °C - lit.
Flash point: 34 °C - closed cup

Evaporation rate: No data available
Flammability (solid, gas): No data available
Upper/lower flammability or explosive limits:
Upper explosion limit: 16 %(V)
Lower explosion limit: 1,8 %(V)
Vapor pressure: 14,53 hPa at 25 °C
Vapor density: 3,11 - (Air = 1.0)
Density: 0,916 g/cm3 at 25 °C - lit.
Relative density: No data available

Water solubility: 1.000 g/l at 20 °C
Partition coefficient: n-octanol/water
Pow: < 1 at 20 °C - Bioaccumulation is not expected.
Autoignition temperature: No data available
Decomposition temperature: No data available
Viscosity
Viscosity, kinematic: No data available
Viscosity, dynamic: 1,7 mPa.s at 25 °C

Explosive properties: No data available
Oxidizing properties: none
Other safety information:
Surface tension: 70,7 mN/m at 1g/l at 20 °C
Relative vapor density: 3,11 - (Air = 1.0)
Boiling point: 120 °C (1013 mbar)
Density: 0.921 g/cm3 (25 °C)
Explosion limit: 1.7 - 11.5 %(V)
Flash point: 34 °C
Ignition temperature: 287 °C

Melting Point: -96 °C
pH value: 4 - 7 (200 g/l, H₂O, 20 °C)
Vapor pressure: 11.33 hPa (20 °C)
Min. Purity Spec: 99% (GC)
Physical Form (at 20°C): Liquid
Boiling Point: 118-119°C(lit.)
Flash Point: 34°C
Refractive Index: 1.403
Long-Term Storage: Store long-term in a cool, dry place

Molecular Weight: 90.12
XLogP3-AA: -0.2
Hydrogen Bond Donor Count: 1
Hydrogen Bond Acceptor Count: 2
Rotatable Bond Count: 2
Exact Mass: 90.068079557
Monoisotopic Mass: 90.068079557
Topological Polar Surface Area: 29.5 Å²
Heavy Atom Count: 6
Formal Charge: 0
Complexity: 28.7

Appearance: colorless clear liquid (est)
Assay: 98.00 to 100.00
Food Chemicals Codex Listed: No
Specific Gravity: 0.92200 @ 25.00 °C.
Melting Point: 119.00 °C. @ 760.00 mm Hg
Boiling Point: 119.00 °C. @ 760.00 mm Hg
Vapor Pressure: 8.152000 mmHg @ 25.00 °C. (est)
Flash Point: 93.00 °F. TCC ( 33.89 °C. )
logP (o/w): -0.342 (est)
Soluble in:
alcohol
water, 1000000 mg/L @ 25 °C
water, 1e+006 mg/L @ 25 °C (est)

FIRST AID MEASURES of 1-METHOXY-2-PROPANOL:
-Description of first-aid measures:
*General advice:
Show this material safety data sheet to the doctor in attendance.

*If inhaled:
After inhalation:
Fresh air.
Call in physician.

*In case of skin contact:
Take off immediately all contaminated clothing.
Rinse skin with water/ shower.

*In case of eye contact:
After eye contact:
Rinse out with plenty of water.
Remove contact lenses.

*If swallowed:
After swallowing:
Immediately make victim drink water (two glasses at most).
Consult a physician.

-Indication of any immediate medical attention and special treatment needed:
No data available

ACCIDENTAL RELEASE MEASURES of 1-METHOXY-2-PROPANOL:
-Environmental precautions:
Do not let product enter drains.

-Methods and materials for containment and cleaning up:
Cover drains.
Collect, bind, and pump off spills.
Observe possible material restrictions.
Take up with liquid-absorbent material.
Dispose of properly.
Clean up affected area.

FIRE FIGHTING MEASURES of 1-METHOXY-2-PROPANOL:
-Extinguishing media:
*Suitable extinguishing media:
Water
Foam
Carbon dioxide (CO2)
Dry powder

*Unsuitable extinguishing media:
For this substance/mixture no limitations of extinguishing agents are given.

-Further information:
Prevent fire extinguishing water from contaminating surface water or the ground water system.

EXPOSURE CONTROLS/PERSONAL PROTECTION of 1-METHOXY-2-PROPANOL:
-Control parameters:
--Ingredients with workplace control parameters:
-Exposure controls:
--Personal protective equipment:

*Eye/face protection:
Use safety glasses.

*Skin protection:
Full contact:
Material: butyl-rubber
Minimum layer thickness: 0,7 mm
Break through time: 480 min

Splash contact:
Material: Nitrile rubber
Minimum layer thickness: 0,4 mm
Break through time: 120 min

-Control of environmental exposure:
Do not let product enter drains.

HANDLING and STORAGE of 1-METHOXY-2-PROPANOL:
-Precautions for safe handling:
*Advice on safe handling:
Work under hood.

*Hygiene measures:
Change contaminated clothing.
Wash hands after working with substance.

-Conditions for safe storage, including any incompatibilities:
*Storage conditions
Keep container tightly closed in a dry and well-ventilated place.

STABILITY and REACTIVITY of 1-METHOXY-2-PROPANOL:
-Chemical stability:
The product is chemically stable under standard ambient conditions (room temperature) .

-Possibility of hazardous reactions:
No data available

SYNONYMS:
1-Methoxy-2-propanol
1-Methoxypropan-2-ol
PGME
Methoxyisopropanol
Closol
Propylene glycol monomethyl ether
2-Propanol, 1-methoxy-
Dowtherm 209
Poly-Solve MPM
Propasol solvent M
Dowanol 33B
2-Methoxy-1-methylethanol
1-Methoxy-2-hydroxypropane
PROPYLENE GLYCOL METHYL ETHER
2-Propanol, methoxy-
Propylene glycol 1-methyl ether
NSC 2409
Dowanol-33B
1-methoxy-propan-2-ol
.alpha.-Propylene glycol monomethyl ether
Methyl proxitol
DSSTox_CID_4284
DSSTox_RID_77354
DSSTox_GSID_24284
UNII-74Z7JO8V3U
Ucar Solvent LM (Obs.)
HSDB 1016
UN3092
BRN 1731270
propyleneglycol monomethylether
AI3-15573
Glycol ether pm
Ucar solvent lm
Solvent PM
Gylcol Ether PM
Icinol PM
Poly-solv MPM
74Z7JO8V3U
Methoxy-2-propanol
3-methoxy-propan-2-ol
Propan-1-methoxy-2-ol
rac-1-methoxy-2-propanol
1,2-PROPYLENE GLYCOL 1-MONOMETHYL ETHER
2-methoxy-1-methyl ethanol
Propan-2-ol, 1-methoxy-
3-01-00-02146 (Beilstein Handbook Reference)
propylene glycol monomethylether
1-Methoxy-2-propanol, 98%
Propyleneglycol monomethyl ether
Methoxypropanol, .alpha. isomer
CHEMBL3186306
DTXSID8024284
NSC2409
WLN: QY1 & 1O1
propylene glycol mono methyl ether
(+/-)2-methoxy-1-methylethanol
NSC-2409
Propylene Glycol 1-Monomethyl Ether
Tox21_201803
Tox21_303269
7109AF
1-Methoxy-2-propanol, >=99.5%
AKOS009158246
MCULE-7513310960
SB44649
SB44662
NCGC00249123-01
NCGC00256978-01
NCGC00259352-01
1-Methoxy-2-propanol, analytical standard
DB-016688
Propylene Glycol Methyl Ether Reagent Grade
FT-0608005
FT-0647598
FT-0654880
FT-0655258
M0126
E72455
Q1884806
1-Methoxy-2-propanol [UN3092] [Flammable liquid]
Z1262237356
2-Propanol, 1-methoxy-
propylene glycol methyl ether
propylene glycol monomethyl ether
Propylene glycol methyl ether,Propyleneglycol monomethyl ether
PGME
Closol
Dowanol pm
MeCH(OH)CH2OMe
PGMME
1-methoxy-2-hydroxypropane
PM-EL
dowanol33b
2-methoxyisopropanol
Propylene Glycol 1-Monomethyl Ether
Solvent PM
Icinol PM
1-methoxy 2-propanol