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EC / List no.: 203-366-1
CAS no.: 106-14-9
Mol. formula: C18H36O3
Overview of Hydroxystearic Acid
Also called 12-hydroxy stearic acid and 12-HSA, hydroxystearic acid is a fatty acid surfactant, emollient and thickener.
12-Hydroxy Stearic Acid is used widely in a variety of personal care and cosmetics products, including skin care preparations, hair products and deodorizing products.
Structurally similar to stearic acid, hydroxystearic acid is entirely vegetable-based and derived from naturally-occurring fats and oils, most commonly castor oil.
12-Hydroxy Stearic Acid is synthesized by oxidizing 2-hexylcyclododecanone with a mixture of permaleic and peracetic acids in methylene chloride.
This forms the lactone of hydroxystearic acid, and alkaline hydrolysis of the lactone produces 12-Hydroxy Stearic Acid.
Sold in solid flakes, hydroxystearic acid has a typical shelf life of up to two years past date of manufacture — the exact shelf life will vary based on storage conditions.
To get the longest life out of hydroxystearic acid, store the chemical according to material safety data sheet (MSDS) recommendations.
Hydroxystearic Acid: An Oleochemical Solution
While many traditional chemicals are classified as petrochemicals, hydroxystearic acid is categorized as an oleochemical.
12-Hydroxy Stearic Acids are produced from petroleum oil-based products, and they are not known for their environmentally-friendly effects — many critics condemn petrochemicals for damaging the air, soil and water.
12-Hydroxy Stearic Acid also tend to absorb easily into the skin, potentially creating issues in human health.
Alternately, oleochemicals are chemicals derived from natural sources, most commonly plant and animal fats.
Because they are typically pollution-free, biodegradable and have very low toxicity, oleochemicals are an attractive alternative to traditional petrochemical compounds.
Consumers are increasingly concerned about the ingredients of their cosmetic products — if something comes into contact with their skin, they want 12-Hydroxy Stearic Acid to be natural and healthy.
Nonflammable, non-reactive and not an explosive hazard, hydroxystearic acid isn’t irritating to skin and doesn’t lead to respiratory distress.
This makes hydroxystearic acid an especially attractive alternative to petroleum-based thickeners, emollients and surfactants on the market.
he most popular use for hydroxystearic acid is in the cosmetics and personal care industry.
Because 12-hydroxy stearic acid is effective in a range of functions, 12-Hydroxy Stearic Acid is a versatile and popular ingredient for many different products.
Some of the most popular applications for hydroxystearic acid include the following products:
Lotions
Creams
Gels
Make-up and decorative cosmetics
Hair care, such as shampoos, conditioners and styling products
Skin care, such as facial care and cleansing, body care and baby care products
SPF enhancement
Sun care, such as sun protection, self-tanning and after-tanning products
Underarm deodorants
In any given cosmetics product, hydroxystearic acid is used in three primary functions — as a surfactant, emollient and thickener.
12-Hydroxy Stearic Acid, also known as 12-hydroxy-octadecanoate or DL-12-hydroxy stearate, belongs to the class of organic compounds known as long-chain fatty acids.
These are fatty acids with an aliphatic tail that contains between 13 and 21 carbon atoms.
12-Hydroxy Stearic Acid is a very hydrophobic molecule, practically insoluble (in water), and relatively neutral.
12-Hydroxy Stearic Acid (12-HSA) is a waxy, castor-derived fatty acid that finds use in lithium complex grease and other high performance greases with automotive and industrial applications.
12-Hydroxy Stearic Acid is an efficient viscosity builder and gelling agent, and will gel hydrocarbons as well as many esters and some silicones.
Salts made from 12-HSA can function as oil/water emulsifiers.
12-Hydroxy Stearic Acid can be used as an emollient in underarm deodorant sticks, gel lipsticks, hair styling products, creams and lotions.
12-Hydroxy Stearic Acid is a castor oil derivative used in a variety of cosmetic applications.
It is often used by formulators as an emollient in skin care products and is also a common surfactant in soaps.
12-Hydroxy Stearic Acid is used predominately in antiperspirants and deodorants, lip gels, hair styling waxes, and skin creams and lotions
2-Hydroxy stearic acid is a saturated hydroxy fatty acid.
12-Hydroxy Stearic Acid is a waxy, odourless, tasteless and cream coloured compound in flakes / powder.
Use and Manufacturing of 12-Hydroxy Stearic Acid
Household & Commercial/Institutional Products
• Personal Care
12-Hydroxy Stearic Acid is used as a surfactant-cleansing agent in cosmetic products.
12-Hydroxy Stearic Acid has been used as a textile lubricant and as a saponifiable base for greases.
12-Hydroxy Stearic Acid-polyethylene glycol block polymers have been approved by FDA for use as surfactants, for dispersions of polyacrylamide retention and draining aids, employed prior to the sheet forming operation in the manufacture of paper and paperboard that come in contact with aqueous and fatty foods.
Lithium greases; chemical intermediates
Used for skin and hair-cleaning purposes and as emulsifiers in cosmetics.
Industry Uses of 12-Hydroxy Stearic Acid
Fillers
Lubricants and lubricant additives
Consumer Uses of 12-Hydroxy Stearic Acid
Drilling Fluid Additives - Lubricant
Lubricants and greases
Personal care products
Methods of Manufacturing of 12-Hydroxy Stearic Acid
12-Hydroxy Stearic Acid may be synthesized as follows: 2-hexylcyclododecanone is oxidized with a mixture of peracetic and permaleic acids in methylene chloride to form the lactone of Hydroxystearic acid.
Alkaline hydrolysis of the lactone leads to the production of Hydroxystearic acid.
Acylcyclododecanones, such as 2-hexylcyclododecanone, can be obtained by the addition of cyclododecanone at the double bond of the respective 1-alkene.
This reaction occurs through a radical-chain mechanism; organic peroxides are used as initiators.
The catalytic hydrogenation of castor oil to 12-Hydroxy Stearic Acid has also been reported.
General Manufacturing Information about 12-Hydroxy Stearic Acid
Industry Processing Sectors
Oil and gas drilling, extraction, and support activities
Paint and coating manufacturing
Petroleum lubricating oil and grease manufacturing
The synthesis of four sugar-based surfactants derived from glucose and (R)-12-Hydroxy Stearic Acid is described.
The surfactants have a hydroxy group in the hydrophobic part, which is either free or acylated using acetyl chloride, hexanoyl chloride, or myristoyl chloride.
Three of the synthesized surfactants are water-soluble and are evaluated with respect to their critical micelle concentrations and hemolytic activities.
The fourth surfactant has limited water solubility and is not further included in the study.
The investigated surfactants are all hemolytic close to their respective critical micelle concentration indicating that their use in parenteral formulations may be limited.
Nevertheless, surfactants having the proposed structure appear as promising alternatives to existing solubilizing agents for pharmaceutical applications.
Description of 12-Hydroxy Stearic Acid
12-Hydroxy stearic acid (12-HSA) is a saturated hydroxy fatty acid. It's a waxy, odourless, tasteless and cream coloured compound in flakes / powder.
appearance creamish flakes or powder
melting point °C min. 70
colour Gardner max. 6
colour (on 1” Lovibond) max 20 yellow / max. 4,5 red
acid value mg KOH/g min. 175
iodine value (Wijs) g I2/100g max. 5
hydroxyl value min. 150
saponification value mg KOH/g 175 - 190
Chemical Properties
white powder
Uses
lubrication: 12-Hydroxy stearic acid (12-HSA) gives better Lithium, Barium and Calcium multi-purpose greases.
It provides excellent resistance to water, oils, solvents and crude petroleum, wide temperature range stability and high drop point.
cosmetics: 12-hydroxy stearic acid is used for gelling liquid Paraffin in creams and ointments, which easily liquefy on the skin.
Esters of 12-hydroxy stearic acid are used in various cosmetic products (lipsticks, deodorant and antiperspirant sticks, shaving creams, etc.).
coatings: 12-hydroxy stearic acid is reacted with acrylic esters to produce hard, durable thermosetting polymers used in the high quality automotive, industrial appliance and metal decorative finishes.
rubber: functions as an activator and internal lubricant for natural and synthetic rubbers
others: 12-hydroxy stearic acid is an useful component in polishes, inks and hot melt adhesives
Uses
Lithium greases, chemical intermediates.
Mixed fatty acid. Acts as plasticizer and internal lubricant.
Its molecular weight is 300.48.
It is high melting, brittle, waxy solid at room temperature.
Used as an activator for natural and synthetic rubber.
It should be stored away from heat to avoid deterioration.
12-hydroxy Stearic acid is a hydroxy fatty acid produced by the hydrogenation of ricinoleic acid.
It is a low molecular weight gelator that self-assembles to form organogels.
Administration of paclitaxel oin 12-hydroxy stearic acid-containing gel nanocarriers enhances tumor growth suppression in an H22 murine hepatocellular carcinoma model.
Formulations containing 12-hydroxy stearic acid have been used in cosmetic products as emollients.
12-Hydroxy Stearic Acid (12-HSA) appended new amphiphilic scaffolds reveal excellent hydrogenation propensity in the presence of aqueous acids and vapors of HCl
The 12 Hydroxy Stearic Acid Flake is available in off white flakes that reflect the purity of the chemical.
Additionally, customers are eased with the availability of the 12 Hydroxy Stearic Acid Powder in varied grades to meet the specifications of the applications.
12-HSA is chemically 12-HYDROXY STEARIC ACID.
It is a wax-like, odorless, tasteless compound.
Uses
As a Surfactant
Thickener in Cosmetics
In Lubricant Production
Manufacturing of plastic products
12-Hydroxy stearic acid is a saturated fatty acid derived from hydrogenated castor oil.
The hydroxyl groups are responsible for the unique properties and applications.
12-Hydroxy stearic acid is a light coloured acid with a high melting point.
12-Hydroxy stearic acid is soluble in solvents as isopropylalcohol, benzene, aceton etc. and is mainly used in the manufacture of lubricating greases as thickening agents.
12-Hydroxy stearic acid is also used as a non-drying fatty acid in the manufacture of alkyd resins, as a PVC lubricant and mould release agent.
12-Hydroxy stearic acid is a saturated fatty acid derived from hydrogenated castor oil.
12-Hydroxy stearic acid is mainly used in the manufacture of lubricating greases as thickening agents.
Applications :
The 12-Hydroxy Stearic Acid is a natural source (castor) used by the cosmetics industry, but also in other multiple industrial applications (lubricants, for example).
Uses
Plastics processing and production: 12-Hydroxy stearic acid is used as an additive in the production of PVC products (films, sheets, window profiles, wall panels, siding, etc.).
12-Hydroxy stearic acid is an additive part (these are different substances and components which are used for the superheat reduction in cylinders of the processing units and provide good sliding of the melts)
Lubricants: 12-Hydroxy stearic acid can be used in lithium, barium and calcium-free high quality glycerol lubricants. These lubricants are predestined for airplanes and cars; they are water-, oil- and temperature resistant;
Cosmetics and perfume: 12-Hydroxy stearic acid can be used in the production of liquid vaseline, is used as a component of cosmetic creams;
Coating compounds: 12-Hydroxy stearic acid reacts to acrylates in the production of stable thermoreactive polymers, which are used in the production of automechanical and industrial plants of high quality and metallic decorative layers.
Production of packaging materials that contact with food.
Rubber products: 12-Hydroxy stearic acid is used as an activating agent and internal lubricant in the production of natural and synthetic rubber products.
Other products: 12-Hydroxy stearic acid is used as a component in polishing agents, printing ink, fusible adhesives and as a hydroxylated substitute for stearic acid.
12-Hydroxy stearic acid is a useful component in hot-melt adhesives, inks and polishes, that reacts with acrylic esters to create durable and strong thermosetting polymers.
These thermosetting polymers are used as a coating in metal-decorative finishes, industrial appliances and high-quality automotive applications.
Application of 12-Hydroxy stearic acid
Manufacture of plastic products: used as an additive in the manufacture of PVC products (films, sheets, window profiles, wall panels, siding, etc.) Part of the additives (it is different in composition and properties of substances that reduce overheating inside cylinder processing equipment, provides good glide melt;
Lubricants: 12-Hydroxy Stearic Acid can be used, for example, in glycerol, free multifunctional lithium, calcium and barium, higher quality lubricants.
These lubricants are designed for airplanes and cars, etc., are resistant to water, oil and solvents wide range of temperature regimes;
Cosmetics and perfumery:
12-Hydroxy Stearic Acid can be used for liquid petrolatum gelling to add shine, or it may be included in the vanishing cream to make them gel consistency, as well as for better spreading on the skin;
Paint production:
12-Hydroxy Stearic Acid reacts with acrylic esters for the production of stable thermosetting polymers, which are commonly used for the production of high quality Automotive and industrial equipment, as well as metal decorative coatings.
Manufacture of packaging materials that have contact with food products
Rubber products:
12-Hydroxy Stearic Acid acts as an activator and internal lubricant for natural and synthetic rubber;
Other products:
12-Hydroxy Stearic Acid is used in the polishing composition, inks, hot melt adhesive, as a substitute for saturated hydroxylated stearic acid.
12-Hydroxy Stearic Acid is the mixed fatty acid obtained by hydrolysis of Hydrogenated Castor Oil.
12-Hydroxy Stearic Acid is high melting, brittle, waxy solid at ambient temperatures.
12-Hydroxy Stearic Acid should be stored away from heat to avoid deterioration.
12-Hydroxy Stearic Acid is insoluble in water and it's solubility in many organic solvents is also limited.
12-Hydroxy Stearic Acid is a non-toxic, non-hazardous material. It is used in the manufacturing of greases.
Competitive Advantages
Competitive rate
Timely deliver
Quality assurance
Used in large industries
Other Details
Calcium & lithium base lubricant grease
Heavy duty grease -hard, durable thermosetting polymer use
Metal decorative finish
Multi purpose grease
Product Description:
12-Hydroxy Stearic Acid is a creamish-colored flake composed of a mixed fatty acid obtained from the hydrolysis of
hydrogenated castor oil.
12-Hydroxy Stearic Acid is a brittle and waxy solid at ambient temperatures that is non-toxic and non-hazardous.
12-Hydroxy Stearic Acid is insoluble in water.
Applications:
12-Hydroxy Stearic Acid is used in the production of lithium and lithium complex greases.
12-Hydroxy Stearic Acid is also used in plastics
lubrication, cosmetics and coatings.
About 12-Hydroxy Stearic Acid
Helpful information
12-Hydroxy Stearic Acid is registered under the REACH Regulation and is manufactured in and / or imported to the European Economic Area, at ≥ 10 000 to < 100 000 tonnes per annum.
12-Hydroxy Stearic Acid is used by consumers, in articles, by professional workers (widespread uses), in formulation or re-packing, at industrial sites and in manufacturing.
Consumer Uses
12-Hydroxy Stearic Acid is used in the following products: washing & cleaning products, adhesives and sealants, lubricants and greases, polishes and waxes, fertilisers, coating products and air care products.
Other release to the environment of 12-Hydroxy Stearic Acid is likely to occur from: indoor use (e.g. machine wash liquids/detergents, automotive care products, paints and coating or adhesives, fragrances and air fresheners), outdoor use, indoor use in close systems with minimal release (e.g. cooling liquids in refrigerators, oil-based electric heaters) and outdoor use in close systems with minimal release (e.g. hydraulic liquids in automotive suspension, lubricants in motor oil and break fluids).
Article service life
Other release to the environment of 12-Hydroxy Stearic Acid is likely to occur from: indoor use (e.g. machine wash liquids/detergents, automotive care products, paints and coating or adhesives, fragrances and air fresheners), outdoor use, indoor use in long-life materials with low release rate (e.g. flooring, furniture, toys, construction materials, curtains, foot-wear, leather products, paper and cardboard products, electronic equipment), outdoor use in long-life materials with low release rate (e.g. metal, wooden and plastic construction and building materials) and outdoor use in long-life materials with high release rate (e.g. tyres, treated wooden products, treated textile and fabric, brake pads in trucks or cars, sanding of buildings (bridges, facades) or vehicles (ships)).
12-Hydroxy Stearic Acid can be found in complex articles, with no release intended: vehicles.
12-Hydroxy Stearic Acid can be found in products with material based on: rubber (e.g. tyres, shoes, toys), stone, plaster, cement, glass or ceramic (e.g. dishes, pots/pans, food storage containers, construction and isolation material), fabrics, textiles and apparel (e.g. clothing, mattress, curtains or carpets, textile toys) and plastic (e.g. food packaging and storage, toys, mobile phones).
12-Hydroxy Stearic Acid is intended to be released from scented: clothes.
Widespread uses by professional workers
12-Hydroxy Stearic Acid is used in the following products: washing & cleaning products and polishes and waxes.
12-Hydroxy Stearic Acid is used in the following areas: formulation of mixtures and/or re-packaging.
12-Hydroxy Stearic Acid is used for the manufacture of: chemicals.
Other release to the environment of 12-Hydroxy Stearic Acid is likely to occur from: indoor use (e.g. machine wash liquids/detergents, automotive care products, paints and coating or adhesives, fragrances and air fresheners), outdoor use and indoor use in close systems with minimal release (e.g. cooling liquids in refrigerators, oil-based electric heaters).
Formulation or re-packing
12-Hydroxy Stearic Acid is used in the following products: polymers, paper chemicals and dyes, lubricants and greases and textile treatment products and dyes.
Release to the environment of 12-Hydroxy Stearic Acid can occur from industrial use: formulation of mixtures and formulation in materials.
Uses at industrial sites
12-Hydroxy Stearic Acid is used in the following products: polymers, washing & cleaning products, textile treatment products and dyes, metal surface treatment products, pH regulators and water treatment products, leather treatment products and lubricants and greases.
12-Hydroxy Stearic Acid is used in the following areas: formulation of mixtures and/or re-packaging.
12-Hydroxy Stearic Acid is used for the manufacture of: chemicals, textile, leather or fur and plastic products.
Release to the environment of 12-Hydroxy Stearic Acid can occur from industrial use: in processing aids at industrial sites, in the production of articles, as processing aid, as an intermediate step in further manufacturing of another substance (use of intermediates) and as processing aid.
Manufacture
Release to the environment of 12-Hydroxy Stearic Acid can occur from industrial use: manufacturing of the substance and as an intermediate step in further manufacturing of another substance (use of intermediates).
Other release to the environment of 12-Hydroxy Stearic Acid is likely to occur from: indoor use (e.g. machine wash liquids/detergents, automotive care products, paints and coating or adhesives, fragrances and air fresheners).
12 Hydroxy Stearic Acid is a saturated C18-Fatty Acid that is a pale Ivory coloured, brittle, hard wax like odourless substance derived from hydrolysis of Hydrogenated Castor Oil.
12-Hydroxy Stearic Acid is suitable for its carboxyl and hydroxyl functional groups in various chemical derivatization processes and is available as Fully Hydrogenated Flakes and Powders.
Applications
12-Hydroxy Stearic Acid is being used in the manufacture of Lithium and Calcium-based multipurpose heavy duty greases, in coatings in both solvent and water-based systems and as a plasticizer.
12-Hydroxy Stearic Acid is also used as an activator and internal lubricant for natural and synthetic rubbers.
This type of derivative is also a source for several important industrial oleo chemicals.
IUPAC NAMES:
12 HSA
12-HSA
12-Hydroxy octadecanoic acid
12-Hydroxy stearic acid
12-Hydroxyoctadecanoic acid
12-hydroxyoctadecanoic acid
12-hydroxyoctadecanoic acid
12-Hydroxy Stearic Acid
12-Hydroxy Stearic Acid
12-Hydroxystearic acid
12-hydroxystearic acid
12-Hydroxystearic Acid
12-hydroxystearic acid
12-hydroxystearic acid (12-HSA)
12-Hydroxystearinsäure
12-hydroxysteraic acid
Octadecanoic acid, 12-hydroxy-
SYNONYMS:
12-HYDROXYOCTADECANOIC ACID
12-Hydroxystearic acid
106-14-9
Octadecanoic acid, 12-hydroxy-
Harwax A
DL-12-Hydroxystearic acid
Cerit Fac 3
Hydrofol acid 200
Ceroxin GL
Barolub FTO
Loxiol G 21
Stearic acid, 12-hydroxy-
12-hydroxy-octadecanoic acid
NSC 2385
DL-12-hydroxy stearic acid
36377-33-0
(R)-12-Hydroxyoctadecanoic acid
12-hydroxy stearic acid
CHEBI:85208
27924-99-8
KOW
CAS-106-14-9
HSDB 5368
12-Hydroxystearic acid homopolymer
EINECS 203-366-1
EINECS 253-004-1
UNII-YXH47AOU0F
(S)-12-Hydroxyoctadecanoic acid
12-Hydroxystearic acid estolide
Octadecanoic acid, 12-hydroxy-, homopolymer
Polyhydroxystearic acid (2300 MW)
12-hydroxy-stearic acid
YXH47AOU0F
EC 203-366-1
4-03-00-00942 (Beilstein Handbook Reference)
POLYHYDROXYSTEARIC ACID
12-HSA
CHEMBL292352
12 HYDROXY STEARIC ACID
(?)-12-Hydroxyoctadecanoic acid
12-Hydroxyoctadecanoic acid, 99%
18417-00-0
NSC-2385
EINECS 227-283-5
EINECS 242-295-0
8039-23-4
FT-0607234
ST51039859
V0108
W-108773
W-110875
Q27158401
12-Hydroxystearic acid, United States Pharmacopeia (USP) Reference Standard
Benzyl(2S,3aS,7aS)-octahydro-1H-indole-2-carboxylate4-methylbenezenesulfonate
78642-86-1
12-hydroxy-octadecanoicaci
12-hydroxystearic
12-hydroxy-stearicaci
12-Hydroxysteric acid
12 hydroxy calcium stearate
12-Hydroxystearic acid Factory
12-Hydroxystearic acid COA TDS MSDS
Twelve hydroxy acid
12-Hydroxystearic acid, technical, 85%
Barolub fto
barolubfto
Cerit Fac 3
ceritfac3
Ceroxin gl
ceroxingl
Harwax A
harwaxa
Hydrofol Acid 200
hydrofolacid200
KOW
Loxiol G 21
12-Hydroxyoctadecanoic acid,12-Hydroxystearic acid
12-Hydroxystearic Acid (200 mg)
12-HSA
12-Hydroxyoctadecanoic Acid 12-
12-Hydroxystearic acid MSDS Free sample
loxiolg21
Octadecanoic acid, 12-hydroxy-
Hydroxystearicacid
LEMOSOL COAGULANT
DL-12-HYDROXYOCTADECANOIC ACID
DL-12-HYDROXYSTEARIC ACID
(+/-)-12-HYDROXYOCTADECANOIC ACID
12-HYDROXYOCTADECANOIC ACID
12-HYDROXYSTEARIC ACID
12-HYDROXYSTEARIC ACID, TECH.
DL-12-Hydroxystearic acid, tech., 90%
hydroxy stearic acid 12
(±)-12-Hydroxyoctadecanoic acid, Technical Grade
d-12HSA
16-Hydroxyoctadecanoic acid
16-Hydroxystearic acid
Polyethylene Glycol Monooleate(2E.O.)
DL-12-Hydroxystearic acid,99+%
DL-12-Hydroxystearic acid,90%,tech.
12-HydroxystearicAcid>
