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2-Diethylaminoethanol is a multifunctional tertiary amino alcohol used as a neutralizing amine, corrosion-control component, polymerization catalyst and chemical intermediate.
2-Diethylaminoethanol combines the alkalinity of a tertiary amine with the reactivity and water compatibility of a primary alcohol.
2-Diethylaminoethanol is used in water treatment, coatings, polyurethane systems, gas treatment, metalworking fluids, surfactants, pharmaceuticals and specialty synthesis.
CHEMICAL IDENTITY AND COMMON NAMES
2-Diethylaminoethanol contains two ethyl groups and one hydroxyethyl group bonded to a tertiary nitrogen atom.
The tertiary amine accepts protons and catalyses selected reactions, while the hydroxyl group supports esterification and reactions with isocyanates.
2-Diethylaminoethanol forms water-soluble salts when neutralized with organic or inorganic acids.
Alkylation of the tertiary nitrogen produces quaternary ammonium derivatives with cationic and surface-active properties.
Common Abbreviations: DEAE and DEEA
Chemical Family: Tertiary alkanolamines
Functional Groups: Tertiary amine and primary alcohol
Synonyms: 2-(Diethylamino)ethanol, 2-(Diethylamino)ethan-1-ol, N,N-Diethylethanolamine, Diethylethanolamine, Diethylaminoethanol, N,N-Diethylmonoethanolamine, Diethylmonoethanolamine, N,N-Diethyl-2-aminoethanol, N,N-Diethyl-2-hydroxyethylamine, N,N-Diethylaminoethanol, Diethyl(2-hydroxyethyl)amine, (2-Hydroxyethyl)diethylamine, N-(2-Hydroxyethyl)diethylamine, N,N-Diethyl-N-(2-hydroxyethyl)amine, 2-Diethylaminoethyl alcohol, 2-(Diethylamino)ethyl alcohol, beta-(Diethylamino)ethanol, β-(Diethylamino)ethanol, beta-Diethylaminoethyl alcohol, β-Diethylaminoethyl alcohol, beta-Hydroxyethyldiethylamine, β-Hydroxyethyldiethylamine, 2-Hydroxytriethylamine, beta-Hydroxytriethylamine, β-Hydroxytriethylamine, N,N-Diethylglycinol, Ethanol, 2-(diethylamino)-, DEAE, DEEA and NSC 8759
TECHNICAL IDENTIFICATION
CAS Number: 100-37-8
EC Number: 202-845-2
Molecular Formula: C6H15NO
Molecular Weight: 117.19 g/mol
IUPAC Name: 2-(Diethylamino)ethan-1-ol
Exact Mass: 117.1154
InChIKey: BFSVOASYOCHEOV-UHFFFAOYSA-N
Canonical SMILES: CCN(CC)CCO
MDL Number: MFCD00002850
UN Number: 2686
PHYSICAL AND CHEMICAL PROPERTIES
Appearance: Clear, colourless to pale yellow liquid
Odour: Strong ammonia-like or amine-like odour
Physical State: Liquid
Freezing Point: Approximately −68 to −70 °C
Boiling Point: Approximately 161–163 °C
Density: Approximately 0.88–0.89 g/cm³ at 20 °C
Flash Point: Approximately 50–52 °C in a closed-cup test
Autoignition Temperature: Approximately 320 °C
Water Solubility: Miscible with water
Other Solubility: Soluble in alcohol, ether, benzene and many polar organic solvents
pH: Approximately 11.5 for a 100 g/L aqueous solution
pKa: Approximately 10.1 for the conjugate acid
LogP: Approximately 0.21 at 23 °C
Vapour Pressure: Approximately 1.9–2.0 hPa at 20–22 °C
Vapour Density: Approximately 4.0 relative to air
Dynamic Viscosity: Approximately 4.0 mPa·s at 25 °C
Refractive Index: Approximately 1.441 at 20 °C
Hygroscopicity: Hygroscopic
Acid-Base Character: Strongly alkaline in aqueous solution
Flammability: Flammable liquid and vapour
Thermal Decomposition: Carbon oxides, nitrogen oxides and irritating or toxic fumes may form during fire
The complete water miscibility of 2-Diethylaminoethanol supports straightforward preparation of aqueous concentrates.
The relatively low vapour pressure provides useful distribution between water, steam and condensate in controlled water-treatment systems.
FUNCTIONAL CHARACTERISTICS
2-Diethylaminoethanol functions as an organic base and neutralizes acids through an exothermic salt-forming reaction.
The resulting salts can improve the water compatibility of fatty acids, resins and other acidic compounds.
The tertiary nitrogen of 2-Diethylaminoethanol catalyses urethane formation and selected resin-curing reactions.
The primary hydroxyl group can react with isocyanates and become incorporated into appropriately designed polyurethane structures.
2-Diethylaminoethanol can absorb carbon dioxide in aqueous systems by promoting bicarbonate formation.
This behaviour supports specialized gas-treatment and regenerable carbon-dioxide-capture formulations.
Esterification of 2-Diethylaminoethanol produces functional amino esters for pharmaceutical, surfactant and specialty-chemical synthesis.
Quaternization provides cationic derivatives used in emulsification, antistatic treatment and surface modification.
PRODUCTION AND COMMERCIAL FORM
Industrial production of 2-Diethylaminoethanol primarily uses the controlled reaction of diethylamine with ethylene oxide.
Nucleophilic ring opening of ethylene oxide forms the hydroxyethyl group in a strongly exothermic reaction.
An alternative manufacturing route reacts diethylamine with ethylene chlorohydrin.
This route requires additional control of chloride-containing by-products and salt removal.
Excess diethylamine, water and light components are removed before fractional distillation of 2-Diethylaminoethanol.
Purification controls residual diethylamine, water, colour, chloride and higher-boiling amino-alcohol by-products.
Commercial 2-Diethylaminoethanol is normally supplied as a clear liquid in technical, high-purity and synthesis grades.
Bulk and packaged forms are available for water treatment, coatings, polymer production and intermediate manufacturing.
APPLICATIONS AND INDUSTRIES
Boiler-water and condensate treatment
2-Diethylaminoethanol functions as a volatile neutralizing amine in steam-generation and condensate-return systems.
The alkaline vapour distributes with steam and neutralizes carbonic acid after condensation.
This neutralization helps maintain condensate pH and reduces carbon-dioxide-related corrosion in return lines.
The organic amine provides alkalinity without introducing the nonvolatile inorganic solids associated with mineral alkalis.
Feed rate is determined from feedwater chemistry, carbon-dioxide loading, system pressure and condensate pH.
Distribution studies are useful in complex systems containing long steam lines or multiple condensate-return points.
Industrial coatings and inks
2-Diethylaminoethanol neutralizes carboxyl-functional acrylic, alkyd, polyester and polyurethane resins.
Partial neutralization converts acidic resin groups into water-compatible salts and supports stable waterborne dispersions.
The selected neutralization level influences resin solubility, viscosity, pigment dispersion and storage stability.
Controlled volatilization during drying assists film formation and development of the final coating properties.
2-Diethylaminoethanol is used in architectural coatings, industrial finishes, baking enamels, printing inks and two-component coating systems.
Compatibility with the resin, pigments, additives and curing package determines the optimum addition level.
Polyurethane production
2-Diethylaminoethanol acts as a tertiary-amine catalyst for reactions between isocyanates and hydroxyl-functional compounds.
The catalytic effect can influence gel development, curing rate and final polymer structure.
The hydroxyl group of 2-Diethylaminoethanol can react with isocyanate groups under suitable conditions.
This reactive character can reduce the amount of freely mobile catalyst remaining in the cured polymer.
2-Diethylaminoethanol is used in selected polyurethane coatings, elastomers, adhesives and foam systems.
Catalyst concentration must be balanced against pot life, rise profile, gel time and final physical properties.
Resin curing and polymer processing
2-Diethylaminoethanol provides basic catalytic activity in selected epoxy, urethane and condensation-resin systems.
The combination of tertiary amine and hydroxyl functionality can accelerate curing or support controlled resin modification.
Excessive catalyst concentration can shorten working time and increase exotherm.
Laboratory cure studies establish the appropriate balance between processing time and final conversion.
Gas treatment and carbon-dioxide capture
Aqueous 2-Diethylaminoethanol solutions can absorb carbon dioxide through base-assisted bicarbonate formation.
This tertiary-amine mechanism can provide favourable cyclic capacity and regeneration behaviour in specialized gas-treatment systems.
2-Diethylaminoethanol can be used alone or blended with faster-reacting activators.
Absorbent concentration, temperature, pressure, corrosion behaviour and regeneration energy determine process suitability.
Metalworking fluids and corrosion-control formulations
2-Diethylaminoethanol neutralizes acidic components in soluble oils, synthetic fluids and semi-synthetic metalworking concentrates.
The resulting amine salts contribute alkalinity, emulsification and corrosion-control performance.
Formulation work must consider metal compatibility, foam, microbial control and nitrosamine-management requirements.
Low secondary-amine impurity and controlled nitrite exposure are important in metalworking-fluid applications.
Surfactants and emulsifiers
2-Diethylaminoethanol serves as an intermediate for amino esters, fatty-acid derivatives and quaternary ammonium compounds.
These derivatives can provide emulsifying, wetting, antistatic, conditioning or dispersing properties.
Acid salts of 2-Diethylaminoethanol can also function as water-compatible emulsifying components.
The selected acid and neutralization ratio determine solubility, surface activity and formulation pH.
Textile and fibre processing
Derivatives of 2-Diethylaminoethanol are used in textile lubricants, softeners, antistatic agents and finishing auxiliaries.
Cationic derivatives provide affinity for negatively charged fibre and surface sites.
2-Diethylaminoethanol also supports the production of functional intermediates for dyeing and textile-processing systems.
Residual amine, colour and odour require control in applications involving light-coloured materials.
Pharmaceutical intermediates
2-Diethylaminoethanol is a precursor for pharmaceutical compounds containing the 2-diethylaminoethyl group.
Esterification with suitable aromatic or aliphatic acids provides functional amino esters, including intermediates associated with local anaesthetic chemistry.
Pharmaceutical-intermediate grades require enhanced control of identity, residual amines, water, colour and elemental impurities.
2-Diethylaminoethanol is an industrial starting material and is not intended for direct therapeutic administration.
Ion-exchange and chromatography materials
2-Diethylaminoethanol provides the diethylaminoethyl functionality used in weak anion-exchange media.
Attachment of this functionality to cellulose, dextran, agarose or synthetic polymers creates positively charged sites under suitable pH conditions.
These materials are used for separating proteins, nucleic acids and other negatively charged substances.
Ligand density, substitution uniformity and residual reagent removal determine chromatographic performance.
Cleaning products and polishes
2-Diethylaminoethanol functions as an alkalinity source, pH adjuster and solubilizing component in selected industrial cleaners and polishes.
Salt formation with acidic formulation components can improve water compatibility and emulsification.
Use concentration must account for corrosivity, odour, evaporation and surface compatibility.
Formulations intended for enclosed environments require effective vapour control and appropriate exposure assessment.
Fine chemicals and organic synthesis
2-Diethylaminoethanol serves as a building block for esters, ethers, quaternary ammonium salts and functional monomers.
The tertiary nitrogen and primary hydroxyl group permit selective reactions at different molecular sites.
2-Diethylaminoethanol is also used in pharmaceutical, agrochemical, polymer and specialty-intermediate development.
High-purity material supports reactions in which water, colour or residual diethylamine can affect selectivity.
GRADE SELECTION AND PRODUCT SUITABILITY
Technical grade 2-Diethylaminoethanol is suitable for water treatment, general synthesis, coatings and industrial formulation.
Typical procurement controls include assay, water content, density, colour and distillation range.
High-purity 2-Diethylaminoethanol is commonly specified at 99.0% assay or higher.
This grade supports demanding coating, polymer, pharmaceutical-intermediate and specialty-synthesis applications.
Water-treatment grade 2-Diethylaminoethanol emphasizes consistent alkalinity, volatility, low chloride and low nonvolatile residue.
These parameters support predictable steam distribution and minimize deposits or contamination.
Coatings grade 2-Diethylaminoethanol focuses on low colour, controlled odour, resin compatibility and consistent neutralization capacity.
Water content and residual diethylamine can influence storage stability, viscosity and film formation.
Polyurethane grade 2-Diethylaminoethanol requires tightly controlled water because moisture reacts with isocyanates.
Catalyst purity and consistent amine value support reproducible cure behaviour.
Pharmaceutical-intermediate grade 2-Diethylaminoethanol requires enhanced traceability and tighter control of related amines, residual solvents and elemental impurities.
Application-specific documentation can support regulated starting-material qualification.
FORMULATION AND PROCESS CONSIDERATIONS
2-Diethylaminoethanol should be added slowly to water with effective agitation.
Cooling may be required because dilution and acid neutralization can release heat.
Neutralization calculations are based on resin acid value, target neutralization percentage and amine equivalent.
Over-neutralization can increase pH, odour, water sensitivity and viscosity instability.
Waterborne coating production commonly introduces 2-Diethylaminoethanol during resin neutralization or final pH adjustment.
Order of addition can affect dispersion quality, viscosity development and localized high-pH exposure.
Boiler-water systems normally use continuous metering into a controlled feed point.
Condensate samples from multiple locations help establish whether the amine distribution is balanced.
Polyurethane processing requires accurate low-level dosing and protection from atmospheric moisture.
Changes in concentration can alter gel time, rise profile, tack-free time and final polymer properties.
Carbon-dioxide absorption systems require control of amine concentration, gas loading, temperature and regeneration conditions.
Materials of construction must tolerate alkaline amine solutions and cyclic thermal exposure.
Nitrite and other nitrosating agents should be excluded from formulations containing secondary-amine impurities.
Low-diethylamine grades provide an additional control for nitrosamine-sensitive applications.
QUALITY, SPECIFICATIONS AND DOCUMENTATION
Routine analysis of 2-Diethylaminoethanol commonly includes gas-chromatographic assay, water content, colour, density and distillation range.
Acid-base titration can determine amine value or neutralization capacity.
Impurity testing can include diethylamine, ethylene glycol, related amino alcohols, chloride and nonvolatile residue.
Elemental impurities and residual process contaminants can be added for pharmaceutical or high-control applications.
A procurement specification normally defines minimum assay, maximum water, colour limit, density, boiling range and impurity profile.
Application-specific requirements can include low chloride, low secondary amine, low metals or controlled nonvolatile residue.
Batch documentation can include a certificate of analysis, safety data sheet, technical data sheet, origin declaration and transport information.
Regulated applications can require additional traceability, change-control and impurity statements.
SAFETY AND REGULATORY CONSIDERATIONS
2-Diethylaminoethanol is a flammable, corrosive and acutely toxic industrial liquid.
2-Diethylaminoethanol is harmful if swallowed and can be toxic following inhalation or skin absorption.
Direct contact causes severe skin burns and serious eye damage.
Vapour can irritate or damage the nose, throat and respiratory tract.
Vapours are heavier than air and can accumulate in low or poorly ventilated areas.
Ignition sources, hot surfaces, sparks, static discharge and open flames must be excluded.
Acid neutralization reactions can generate substantial heat and splashing.
Strong oxidizing agents can cause vigorous reactions or fire.
Firefighting media include alcohol-resistant foam, dry chemical, carbon dioxide and water fog.
Fire conditions can produce carbon monoxide, carbon dioxide, nitrogen oxides and other toxic fumes.
Transport Name: 2-Diethylaminoethanol
UN Number: 2686
Primary Transport Class: 8
Subsidiary Hazard: 3
Packing Group: II
FIRST AID
Inhalation: Move the exposed person immediately to fresh air and keep the person at rest.
Obtain urgent medical attention because respiratory effects can progress after exposure.
Skin Contact: Remove contaminated clothing and rinse the affected skin immediately with large amounts of water for at least 15 minutes.
Obtain immediate medical attention for chemical burns or suspected skin absorption.
Eye Contact: Rinse cautiously with clean water for at least 15 minutes while holding the eyelids open.
Remove contact lenses when easy to do and obtain immediate specialist medical attention.
Ingestion: Rinse the mouth and do not induce vomiting.
Obtain immediate medical assistance because corrosive injury and systemic toxicity are possible.
Note to Physicians: Treat chemical burns and systemic exposure symptomatically and supportively.
Evaluation should include the airway, respiratory function, eyes, skin and gastrointestinal tract.
HANDLING AND STORAGE
Handling: Handle 2-Diethylaminoethanol in a closed system with suitable grounding and bonding.
Prevent inhalation, skin contact, eye contact and uncontrolled release.
Ventilation: Provide local exhaust ventilation at transfer, sampling, blending and packaging points.
Use approved respiratory protection when engineering controls cannot maintain safe airborne concentrations.
Storage: Store 2-Diethylaminoethanol in tightly closed containers in a cool, dry and well-ventilated flammable-liquid area.
Protect 2-Diethylaminoethanol from moisture, heat, sunlight and ignition sources.
Incompatibilities: Keep 2-Diethylaminoethanol away from strong acids, oxidizing agents, acid chlorides and uncontrolled reactive chemicals.
Avoid copper, copper alloys and other construction materials that are incompatible with alkaline amines.
Packaging: Use approved steel drums, compatible intermediate bulk containers or dedicated bulk tanks.
Containers and transfer equipment must be suitable for corrosive and flammable liquids.
PACKAGING AND PROCUREMENT CONSIDERATIONS
Commercial packaging for 2-Diethylaminoethanol includes steel drums, compatible intermediate bulk containers and bulk-tank deliveries.
Smaller sealed containers are suitable for laboratory, development and high-purity applications.
Bulk systems benefit from dry inert-gas blanketing, closed transfer and controlled venting.
Grounding, bonding and suitable fire protection are required during unloading and storage.
A purchasing inquiry should state the intended application, required assay, maximum water, colour, chloride limit, secondary-amine limit and annual volume.
Preferred packaging, destination, delivery conditions and documentation requirements should also be defined.
ATAMAN KIMYA SUPPLY AND CONTACT
Ataman Kimya supports the supply of 2-Diethylaminoethanol for water treatment, coatings, polymers, gas treatment, pharmaceutical intermediates and specialty synthesis.
Ataman Kimya can coordinate grade selection, specification alignment, documentation, packaging and delivery planning.
Email: info@atamankimya.com
Phone: +90 216 577 10 10
