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2-Methyl-4-Isothiazolin-3-One is a potent antimicrobial agent widely used as a preservative in industrial and consumer products.
This biocide exhibits broad-spectrum activity against bacteria, fungi, and algae, ensuring product stability and longevity.
2-Methyl-4-Isothiazolin-3-One is valued for its effectiveness at low concentrations, making it a cost-efficient choice for preservation.
CAS Number: 2682-20-4
EC Number: 220-239-6
Molecular Formula: C4H5NOS
Molecular Weight: 115.15 g/mol
Synonyms: 2-Methyl-4-Isothiazolin-3-One, MIT, Isothiazolone, Methylisothiazolinone, 2-Methylisothiazolin-3-One, Preservative MIT, 2-Methyl-3-Isothiazolone, 4-Isothiazolin-3-One, 2-Methyl Derivative, Biocide 2-Methyl-4-Isothiazolin-3-One, Methylisothiazolinone Antimicrobial, Methylisothiazolinone Preservative, MIT Industrial Grade, MIT Cosmetic Grade, MIT Biocide Additive, 2-Methyl-4-Isothiazolin-3-One for Paints, Water Treatment Biocide MIT, 2-Methyl-4-Isothiazolin-3-One for Adhesives
APPLICATIONS
2-Methyl-4-Isothiazolin-3-One is widely used in paints and coatings to prevent microbial growth and enhance product shelf life.
2-Methyl-4-Isothiazolin-3-One is employed in adhesives and sealants as a preservative, ensuring stability during storage.
2-Methyl-4-Isothiazolin-3-One is incorporated into industrial water treatment systems to control microbial contamination.
2-Methyl-4-Isothiazolin-3-One is applied in personal care products, such as shampoos and lotions, as an antimicrobial preservative.
2-Methyl-4-Isothiazolin-3-One is used in household cleaning agents, providing long-lasting protection against microbial growth.
2-Methyl-4-Isothiazolin-3-One is added to laundry detergents to prevent spoilage and maintain product integrity.
2-Methyl-4-Isothiazolin-3-One is utilized in oilfield applications to prevent microbial fouling in drilling fluids and production systems.
2-Methyl-4-Isothiazolin-3-One is employed in industrial cooling towers to inhibit the growth of algae and bacteria.
2-Methyl-4-Isothiazolin-3-One is included in metalworking fluids to prevent microbial contamination and extend fluid life.
2-Methyl-4-Isothiazolin-3-One is a preferred biocide in paper and pulp manufacturing for controlling microbial growth during processing.
2-Methyl-4-Isothiazolin-3-One is used in textile finishing treatments to prevent microbial degradation of fabrics.
2-Methyl-4-Isothiazolin-3-One is found in ink formulations to maintain stability and prevent microbial contamination.
2-Methyl-4-Isothiazolin-3-One is applied in agricultural products, such as fertilizers and pesticides, to enhance shelf life.
2-Methyl-4-Isothiazolin-3-One is incorporated into construction materials, including concrete additives, to prevent microbial growth.
2-Methyl-4-Isothiazolin-3-One is utilized in marine applications, such as antifouling coatings, to prevent biofouling on surfaces.
2-Methyl-4-Isothiazolin-3-One is employed in disinfectant formulations for hospitals and other healthcare environments.
2-Methyl-4-Isothiazolin-3-One is used in specialty chemicals for microbial control in sensitive applications.
2-Methyl-4-Isothiazolin-3-One is found in deodorizers and air fresheners to prevent bacterial growth in the product.
2-Methyl-4-Isothiazolin-3-One is added to carpet and upholstery cleaners to ensure long-term microbial protection.
2-Methyl-4-Isothiazolin-3-One is applied in the preservation of wood and wood-based products.
2-Methyl-4-Isothiazolin-3-One is used in liquid hand soaps and dishwashing liquids for enhanced product stability.
2-Methyl-4-Isothiazolin-3-One is found in swimming pool and spa treatments for controlling microbial contamination.
2-Methyl-4-Isothiazolin-3-One is employed in specialty lubricants to prevent microbial degradation in high-moisture environments.
2-Methyl-4-Isothiazolin-3-One is used in automotive care products, such as cleaners and waxes, for extended shelf life.
DESCRIPTION
2-Methyl-4-Isothiazolin-3-One is a clear to pale yellow liquid with a slight characteristic odor.
This compound exhibits rapid antimicrobial activity against a broad spectrum of bacteria, fungi, and algae.
2-Methyl-4-Isothiazolin-3-One is highly effective at low concentrations, reducing the risk of product spoilage and microbial contamination.
2-Methyl-4-Isothiazolin-3-One demonstrates excellent thermal stability, making it suitable for use in a variety of industrial processes.
This biocide is compatible with anionic, cationic, and nonionic surfactants, allowing for seamless integration into diverse formulations.
2-Methyl-4-Isothiazolin-3-One is readily biodegradable under aerobic conditions, aligning with environmental sustainability goals.
2-Methyl-4-Isothiazolin-3-One is stable over a wide pH range, ensuring consistent performance in both acidic and alkaline systems.
This antimicrobial agent is widely used in formulations requiring long-term preservation and protection against microbial growth.
2-Methyl-4-Isothiazolin-3-One is a cost-effective and efficient solution for preserving water-based and oil-based products.
PROPERTIES
Chemical Formula: C4H5NOS
Molecular Weight: 115.15 g/mol
Common Name: 2-Methyl-4-Isothiazolin-3-One
Appearance: Clear to pale yellow liquid
Density: Approx. 1.03 g/cm³
Melting Point: Not applicable (liquid)
Boiling Point: Approx. 200°C (decomposes)
Solubility: Miscible with water and polar solvents
Reactivity: Stable under normal conditions; avoid strong oxidizing agents
Chemical Stability: Stable in recommended storage conditions
Storage Temperature: Store at 5–25°C in a dry, ventilated area
pH (1% Solution): Approx. 4.0–6.0
FIRST AID
Inhalation:
If vapors or aerosols of 2-Methyl-4-Isothiazolin-3-One are inhaled, move the affected person to fresh air immediately.
If breathing difficulties persist, seek medical attention.
If the person is not breathing, administer artificial respiration.
Keep the affected person warm and at rest.
Skin Contact:
Wash the affected area thoroughly with soap and water.
If skin irritation or rash develops, seek medical attention.
Remove contaminated clothing and wash before reuse.
Eye Contact:
Flush eyes with plenty of water for at least 15 minutes, lifting upper and lower eyelids.
Seek immediate medical attention if irritation or redness persists.
Remove contact lenses if present and easy to do; continue rinsing.
Ingestion:
If 2-Methyl-4-Isothiazolin-3-One is ingested, rinse the mouth thoroughly with water.
Do not induce vomiting unless instructed by medical personnel.
Seek immediate medical attention if discomfort persists.
If the person is conscious, give small sips of water to drink.
Note to Physicians:
Treat symptomatically.
No specific antidote.
Provide supportive care.
HANDLING AND STORAGE
Handling:
Personal Protection:
Wear appropriate personal protective equipment (PPE), such as gloves, safety goggles, and protective clothing, when handling 2-Methyl-4-Isothiazolin-3-One.
Use in a well-ventilated area to minimize exposure to vapors or aerosols.
Ventilation:
Ensure proper ventilation during handling to prevent airborne particle accumulation.
Use local exhaust systems if necessary.
Avoidance:
Avoid direct contact with eyes, skin, and clothing.
Do not eat, drink, or smoke while handling.
Wash hands thoroughly after handling.
Spill and Leak Procedures:
Contain spills to prevent further release.
Absorb with inert material (e.g., sand, vermiculite) and collect for disposal.
Dispose of waste according to local regulations.
Storage:
Store in a cool, dry, well-ventilated area away from heat sources and incompatible materials.
Keep containers tightly closed when not in use.
Protect from contamination and extreme temperatures.
Handling Cautions:
Avoid exposure to strong oxidizing agents.
Ensure storage containers are clean and compatible with the material.
