2-OCTYL-2H-ISOTHIAZOL-3-ONE (OIT)

2-octyl-2H-isothiazol-3-one (OIT) is a member of the class of 1,2-thiazole that is 1,2-thiazol-3-one substituted on the nitrogen (position 2) by an octyl group. 
A fungicide and antibacterial agent, 2-octyl-2H-isothiazol-3-one (OIT) is used for treatment of canker and other fungal and bacterial diseases in fruit trees. 
2-octyl-2H-isothiazol-3-one (OIT) is Soluble in organic solvents, slightly soluble in water, is a low toxicity, high efficiency, broad-spectrum anti-mold agent, has a strong killing effect on mold, can achieve the ideal anti-mold effect. 

CAS Number : 26530-20-1
EC  Number : 247-761-7
Molecular Formula :    C11H19NOS
Molecular Weight  :     213.34

2-octyl-2H-isothiazol-3-one (OIT) is a member of the class of 1,2-thiazole that is 1,2-thiazol-3-one substituted on the nitrogen (position 2) by an octyl group. 
A fungicide and antibacterial agent, 2-octyl-2H-isothiazol-3-one (OIT) is used for treatment of canker and other fungal and bacterial diseases in fruit trees. 
2-octyl-2H-isothiazol-3-one (OIT) is no longer approved for use within the European Union. 
2-octyl-2H-isothiazol-3-one (OIT) has a role as an environmental contaminant, a xenobiotic, an antifungal agrochemical and an antibacterial agent.

2-octyl-2H-isothiazol-3-one (OIT) is a clear dark amber liquid. 
Used as a fungicide.

Use of 2-octyl-2H-isothiazol-3-one (OIT)
Used as an intermediate in organic synthesis. 
Liquid, soluble in organic solvents, slightly soluble in water, is a low toxicity, high efficiency, broad-spectrum type fungicide, has a strong killing effect on mold, can achieve the desired effect of mildew. 
Can be widely used in paint, paint, lubricating oil, shoe polish, leather chemical, wood products and cultural relics protection and many other products. 
No VOC, strong light and high temperature stability, sterilization broad-spectrum high efficiency, can effectively prevent bacteria and fungi in plastic.

2-octyl-2H-isothiazol-3-one (OIT) is Soluble in organic solvents, slightly soluble in water, is a low toxicity, high efficiency, broad-spectrum anti-mold agent, has a strong killing effect on mold, can achieve the ideal anti-mold effect. 
2-octyl-2H-isothiazol-3-one (OIT) can be widely used in many products such as coatings, paints, lubricants, shoe polish, leather chemistry, wood products and cultural relics protection. VOC-free, stable under strong light and high temperature, broad-spectrum and efficient sterilization, which can effectively prevent bacteria and fungi in plastics.

2-octyl-2H-isothiazol-3-one (OIT) is the organic compound with the formula SC(Cl)=C(Cl)C(O)NC7H15. 
2-octyl-2H-isothiazol-3-one (OIT) is a white solid that melts near room temperature. 
2-octyl-2H-isothiazol-3-one (OIT) is an isothiazolinone, a class of heterocyclic compounds used as biocides. 
2-octyl-2H-isothiazol-3-one (OIT) has attracted attention as an antifouling compound. 
2-octyl-2H-isothiazol-3-one (OIT) is a replacement for organotin compounds that have been largely banned for causing environmental damage. 

2-octyl-2H-isothiazol-3-one (OIT) however is itself controversial.
2-octyl-2H-isothiazol-3-one (OIT) is a broad-spectrum and long-lasting bactericidal agent. 
2-octyl-2H-isothiazol-3-one (OIT) offers good uniformity of dispersion, low toxicity, easy to operate, thermal stability and free from VOC. 
2-octyl-2H-isothiazol-3-one (OIT) is stable in intense ultraviolet and acid rain environment. 
2-octyl-2H-isothiazol-3-one (OIT) is used in plastic and building materials.

2-octyl-2H-isothiazol-3-one (OIT) is light yellow oil clear dark amber liquid effective against mildew, bacteria and fungi. 
2-octyl-2H-isothiazol-3-one (OIT) is widely used as fungicide, antimicrobial agent and in a variety of industrial applications, such as water treatment, paper pulp, coating & painting, personal care products and cosmetics.

2-octyl-2H-isothiazol-3-one (OIT) Chemical Properties:
Melting point: <25 °C
Boiling point: 120°C
Density: 1.04
Vapor pressure: 4.9hPa at 25℃
Refractive index: 1.5500 (estimate)
Fp: 23℃
Storage temp.: Sealed in dry,2-8°C
Form: neat
pka: -2.04±0.20(Predicted)
Color: White or Colorless to Yellow
Water Solubility: <0.1 g/100 mL at 19 ºC
Merck: 14,6755
BRN: 1211137
Stability: Stable. Incompatible with strong oxidizing agents.
InChIKey: JPMIIZHYYWMHDT-UHFFFAOYSA-N
LogP: 2.61 at 25℃

Uses of 2-octyl-2H-isothiazol-3-one (OIT)
Fungicide. Biocide in cooling-tower water, paints, cutting oils, cosmetics and shampoo; for leather preservation.
2-octyl-2H-isothiazol-3-one (OIT) is a mildeweide; bactericide; fungicide; biocide in cooling-tower water; in paints, cutting oils, cosmetics, and shampoos; leather preservation; wound protectant for pruning cuts.
2-octyl-2H-isothiazol-3-one (OIT) is effective against mildew, bacteria, and fungi. 
2-octyl-2H-isothiazol-3-one (OIT) is widely used in a variety of industrial applications. 
Such as water treatment, paper pulp, coating & painting, metal cutting fluid, personal care products, cosmetics, etc.

2-octyl-2H-isothiazol-3-one (OIT) has the advantage of broad-spectrum antibiosis. 
2-octyl-2H-isothiazol-3-one (OIT) has a good ability to inhibit fungi, bacteria, mold, and enzyme bacteria.
2-octyl-2H-isothiazol-3-one (OIT) has low toxicity. 
2-octyl-2H-isothiazol-3-one (OIT) contains no formaldehyde and has no peculiar smell.
2-octyl-2H-isothiazol-3-one (OIT) has a strong capability of killing mildew, the effect is obviously superior to that of the traditional mildew inhibitor, and the octyl isothiazolinone (OIT) is an updated product of the traditional paint film mildew inhibitor.

2-octyl-2H-isothiazol-3-one (OIT) is harmless to the environment, can be naturally degraded into non-toxic substances, and does not pollute the environment.
2-octyl-2H-isothiazol-3-one (OIT) used as an intermediate in organic synthesis. 
Liquid, soluble in organic solvents, slightly soluble in water, is a low toxicity, high efficiency, broad-spectrum type fungicide, has a strong killing effect on mold, can achieve the desired effect of mildew. 
Can be widely used in paint, paint, lubricating oil, shoe polish, leather chemical, wood products and cultural relics protection and many other products.
No VOC, strong light and high temperature stability, sterilization broad-spectrum high efficiency, can effectively prevent bacteria and fungi in plastic.

First Aid Measures of 2-octyl-2H-isothiazol-3-one (OIT)

EYES: 
First check the victim for contact lenses and remove if present. 
Flush victim's eyes with water or normal saline solution for 20 to 30 minutes while simultaneously calling a hospital or poison control center. 
Do not put any ointments, oils, or medication in the victim's eyes without specific instructions from a physician. 
IMMEDIATELY transport the victim after flushing eyes to a hospital even if no symptoms (such as redness or irritation) develop.

SKIN: 
IMMEDIATELY flood affected skin with water while removing and isolating all contaminated clothing. 
Gently wash all affected skin areas thoroughly with soap and water. 
If symptoms such as redness or irritation develop, IMMEDIATELY call a physician and be prepared to transport the victim to a hospital for treatment.

INHALATION: 
IMMEDIATELY leave the contaminated area; take deep breaths of fresh air. 
If symptoms (such as wheezing, coughing, shortness of breath, or burning in the mouth, throat, or chest) develop, call a physician and be prepared to transport the victim to a hospital. Provide proper respiratory protection to rescuers entering an unknown atmosphere. 
Whenever possible, Self-Contained Breathing Apparatus (SCBA) should be used; if not available, use a level of protection greater than or equal to that advised under Protective Clothing.

INGESTION: 
DO NOT INDUCE VOMITING. 
Corrosive chemicals will destroy the membranes of the mouth, throat, and esophagus and, in addition, have a high risk of being aspirated into the victim's lungs during vomiting which increases the medical problems. 
If the victim is conscious and not convulsing, give 1 or 2 glasses of water to dilute the chemical and IMMEDIATELY call a hospital or poison control center. 
IMMEDIATELY transport the victim to a hospital. 
If the victim is convulsing or unconscious, do not give anything by mouth, ensure that the victim's airway is open and lay the victim on his/her side with the head lower than the body. 
DO NOT INDUCE VOMITING. 
Transport the victim IMMEDIATELY to a hospital. 

Substance identity

EC / List no.: 247-761-7
CAS no.: 26530-20-1
Mol. formula: C11H19NOS

Hazard classification & labelling of 2-octyl-2H-isothiazol-3-one (OIT)
Danger! According to the harmonised classification and labelling (ATP15) approved by the European Union, this substance is fatal if inhaled, is toxic if swallowed, is toxic in contact with skin, causes severe skin burns and eye damage, is very toxic to aquatic life, is very toxic to aquatic life with long lasting effects, causes serious eye damage and may cause an allergic skin reaction.

About 2-octyl-2H-isothiazol-3-one (OIT)
2-octyl-2H-isothiazol-3-one (OIT) is registered under the REACH Regulation and is manufactured in and / or imported to the European Economic Area, at ≥ 1 to < 10 tonnes per annum.
2-octyl-2H-isothiazol-3-one (OIT) is used in formulation or re-packing.

Biocidal Uses of 2-octyl-2H-isothiazol-3-one (OIT)
2-octyl-2H-isothiazol-3-one (OIT) is approved for use as a biocide in the EEA and/or Switzerland, for: wood preservation.
2-octyl-2H-isothiazol-3-one (OIT) is being reviewed for use as a biocide in the EEA and/or Switzerland, for: product preservation, preservation films, preservation of fibres, leather, rubber, or polymers, preservation for construction materials, preservation for liquid systems, preservation for working / cutting fluids.

Consumer Uses of 2-octyl-2H-isothiazol-3-one (OIT)
ECHA has no public registered data indicating whether or in which chemical products the substance might be used. 
ECHA has no public registered data on the routes by which this substance is most likely to be released to the environment.

Article service life of 2-octyl-2H-isothiazol-3-one (OIT)
ECHA has no public registered data on the routes by which 2-octyl-2H-isothiazol-3-one (OIT) is most likely to be released to the environment. 
ECHA has no public registered data indicating whether or into which articles the substance might have been processed.

Widespread uses by professional workers of 2-octyl-2H-isothiazol-3-one (OIT) 
ECHA has no public registered data indicating whether or in which chemical products the substance might be used. 
ECHA has no public registered data on the types of manufacture using this substance. 
ECHA has no public registered data on the routes by which this substance is most likely to be released to the environment.

Formulation or re-packing of 2-octyl-2H-isothiazol-3-one (OIT) 
2-octyl-2H-isothiazol-3-one (OIT)  is used in the following products: biocides (e.g. disinfectants, pest control products). Release to the environment of this substance can occur from industrial use: formulation of mixtures.

Uses at industrial sites of 2-octyl-2H-isothiazol-3-one (OIT) 
ECHA has no public registered data indicating whether or in which chemical products the substance might be used. 
ECHA has no public registered data on the types of manufacture using this substance. 
ECHA has no public registered data on the routes by which this substance is most likely to be released to the environment.

Manufacture of 2-octyl-2H-isothiazol-3-one (OIT) 
ECHA has no public registered data on the routes by which 2-octyl-2H-isothiazol-3-one (OIT)  is most likely to be released to the environment.

Synonyms:
2-n-octyl-4-isothiazolin-3-one
2-octyl-2H-isothiazol-3-one
2-octyl-2H-isothiazol-3-one
2-octyl-2H-isothiazol-3-one (OIT)
Octhilinone
octhilinone (ISO); 2-octyl-2H-isothiazol-3-one
octhilinone (ISO); 2-octyl-2H-isothiazol-3-one; [OIT]
octhilinone (ISO);2-octyl-2H-isothiazol-3-one; [OIT]
2-Octil-2H-isotiazol-3-ona (OIT) (es)
2-Octil-2H-isotiazol-3-ona (OIT) (pt)
2-octil-2H-isotiazol-3-onă (OIT) (ro)
2-octyl-2H-isothiazol-3-on (OIT) (da)
2-Octyl-2H-isothiazol-3-on (OIT) (de)
2-octyl-2H-isothiazol-3-one (OIT) (mt)
2-octyl-2H-isothiazol-3-one (OIT) (no)
2-octyl-2H-isothiazole-3-one (OIT) (fr)
2-Octyl-2H-isothiazool-3-on (OIT) (nl)
2-oktil-2H-izotiazol-3-on (OIT) (hr)
2-oktil-2H-izotiazol-3-on (OIT) (hu)
2-oktil-2H-izotiazol-3-on (OIT) (sl)
2-oktil-2H-izotiazol-3-onas (OIT) (lt)
2-Oktil-2H-izotiazol-3-ons (OIT) (lv)
2-oktyl-2H-isotiazol-3-on (no)
2-oktyl-2H-isotiazol-3-on (OIT) (sv)
2-oktyl-2H-izotiazol-3-ón (OIT) (sk)
2-oktylo-2H-izotiazol-3-on (OIT) (pl)
2-oktyltetrahydroisothiazol-3-on (OIT) (cs)
2-oktyyli-2H-isotiatsol-3-oni (OIT) (fi)
2-oktüül-2H-isotiasool-3-oon (OIT) (et)
2-ottil-2H-isotiazol-3-one (OIT) (it)
2-οκτυλ-2H-ισοθειαζολόνη-3 (OIT) (el)
2-октил-2H-изотиазол-3-он (OIT) (bg)
octhilinon (ISO); 2-octyl-2H-isothiazol-3-on; [OIT] (da)
Octhilinon (ISO); 2-Octyl-2H-isothiazol-3-on; [OIT] (de)
octhilinone (ISO); 2-octyl-2H-isothiazol-3-one; [OIT] (fr)
octhilinone (ISO); 2-octyl-2H-isothiazool-3-on; [OIT] (nl)
octhilinone (οκθειλινόνη) (ISO)· 2-οκτυλ-2H-ισοθειαζολόνη-3 [OIT] (el)
Octilinona (ISO); 2-octil-2H-isotiazol-3-ona; [OIT] (es)
octilinona (ISO); 2-octil-2H-isotiazol-3-ona; [OIT] (pt)
octilinone (ISO); 2-ottil-2H-isotiazol-3-one; [OIT] (it)
octilinonă (ISO); 2-octil-2H-izotiazol-3-onă; [OIT] (ro)
okthilinon (ISO); 2-oktyl-2H-isothiazol-3-on; [OIT] (cs)
oktilinon (ISO); 2-oktil-2H-isotijażol-3-on; [OIT] (mt)
oktilinon (ISO); 2-oktil-2H-izotiazol-3-on; [OIT] (hr)
oktilinon (ISO); 2-oktil-2H-izotiazol-3-on; [OIT] (hu)
oktilinon (ISO); 2-oktil-2H-izotiazol-3-on; [OIT] (sl)
oktilinon (ISO); 2-oktyl-2H-isotiazol-3-on; [OIT] (sv)
oktilinonas (ISO); 2-oktil-2H-izotiazol-3-onas; [OIT] (lt)
oktilinoni (ISO); 2-oktyyli-2H-isotiatsol-3-oni; [OIT] (fi)
oktilinons (ISO); 2-oktil-2H-izotiazol-3-ons; [OIT] (lv)
Oktilinoon (ISO); 2-oktüül-2H-isotiasool-3-oon; [OIT] (et)
oktilinón (ISO); 2-oktyl-2H-izotiazol-3-ón; [OIT] (sk)
oktylinon (ISO); 2-oktylo-2H-izotiazol-3-on; [OIT] (pl)
октилинон (ISO); 2-октил-2H-изотиазол-3-он; [OIT] (bg)
3(2H)-Isothiazolone, 2-octyl-
2-N-Octyl-4-isothiazolin-3-on
2-n-Octyl-4-isothiazolin-3-one
2-n-Octyl-4-isothiazolinone-3-one
2-octyl-1,2-thiazol-3-one
2-octyl-2,3-dihydro-1,2-thiazol-3-one
2-octyl-2,3-dihydro-1,2-thiazol-3-one
2-Octyl-2H-isothiazol-3-one
2-octyl-2H-isothiazol-3-one
2-octyl-2h-isothiazol-3-one
2-octylisothiazol-3(2H)-one
octhilinone (ISO)
Octylisothiazolinone
2-n-Octyl-4-isothiazolin-3-one
1135442-68-0
1135442-68-0
122667-23-6
12673-72-2
12673-72-2
1617530-25-2
1617530-25-2
245125-70-6
245125-70-6
249757-59-3
249757-59-3
26530-20-1
Octhilinone
26530-20-1
2-Octyl-4-isothiazolin-3-one
2-octylisothiazol-3(2H)-one
2-n-Octyl-4-isothiazolin-3-one
2-Octyl-3-isothiazolone
Pancil
2-Octyl-2H-isothiazol-3-one
2-Octyl-3(2H)-isothiazolone
Kathon 893
Skane 8
3(2H)-Isothiazolone, 2-octyl-
Skane M-8
Kathon 893F
Micro-chek skane
Kathon LM
Microbicide M-8
2-octyl-1,2-thiazol-3-one
Micro-chek 11
Micro-chek 11D
Kathon
Kathon SP 70
Kathon LP preservative
Kathon 4200
RH 893
4-Isothiazolin-3-one, 2-octyl-
Octyl-3(2H)-isothiazolone
2-Octyl-3-isothioazolone
2-Octyl-3-isothiazolinone
Octyl-4-isothiazol-3-one
2-n-Octyl-3-isothiazolone
4LFS24GD0V
MLS002415697
DTXSID1025805
CHEBI:81936
2-octyl-1,2-thiazol-3(2H)-one
RH-893
SMR001370885
Pancil-T
Skane M8
DTXCID105805
Caswell No. 613C
Vinylzene IT 3000DIDP
C11H19NOS
Octhilinone [ISO]
CAS-26530-20-1
Octhilinone [ANSI:BSI:ISO]
CCRIS 6082
EINECS 247-761-7
UNII-4LFS24GD0V
EPA Pesticide Chemical Code 099901
BRN 1211137
Pancil T
Skane M 8
Octylisothiazolinon, OIT
OCTHILINONE [MI]
Vinyzene IT 3000DIDP
SCHEMBL15648
cid_33528
SCHEMBL396433
CHEMBL1562104
BDBM66023
HSDB 6713
KORALONE 500 PRESERVATIVE
2-Octyl-4-Isothiazolin-3-Ketone
OCTYLISOTHIAZOLINONE [INCI]
ZINC2012904
Tox21_201459
Tox21_300566
MFCD00072473
AKOS015897428
3(2H)-ISOTHIAZOLONE, 2-OCTYL
NCGC00091875-01
NCGC00091875-02
NCGC00091875-03
NCGC00091875-04
NCGC00091875-05
NCGC00254466-01
NCGC00259010-01
AS-11894
Octhilinone 10 microg/mL in Acetonitrile
DB-028182
FT-0613248
O0343
O0378
C18752
D91863
Q2013949
W-107168
2-Octyl-4-isothiazolin-3-one, PESTANAL(R), analytical standard
247-761-7 [EINECS]
26530-20-1 [RN]
2-n-Octyl-4-isothiazolin-3-one
2-Octyl-1,2-thiazol-3(2H)-on [German] [ACD/IUPAC Name]
2-Octyl-1,2-thiazol-3(2H)-one [ACD/IUPAC Name]
2-Octyl-1,2-thiazol-3(2H)-one [French] [ACD/IUPAC Name]
2-Octyl-3(2H)-isothiazolone
2-Octyl-3-isothiazolone
2-Octyl-4-isothiazolin-3-one
3(2H)-Isothiazolone, 2-octyl- [ACD/Index Name]
4LFS24GD0V
MFCD00072473 [MDL number]
NX8156900
octhilinone [ANSI] [BSI] [ISO]
T5SNVJ B8 [WLN]
[26530-20-1] [RN]
1185109-79-8 [RN]
2-n-Octyl-3-isothiazolone
2-octyl-1,2-thiazol-3-one
2-octyl-2,3-dihydro-1,2-thiazol-3-one
2-Octyl-3-isothiazolinone
2-Octyl-3-isothioazolone
2-octylisothiazol-3-one
3-ethoxy-N-[(5-methyl-2-thiophenyl)methyl]-1-propanamine
decene
EINECS 247-761-7
Kathon
Kathon 4200
Kathon 893
Kathon 893F
Kathon LM
Kathon LP preservative
Kathon SP 70
Microbicide M-8
Micro-chek 11
Micro-chek 11D
Micro-chek skane
NCGC00091875-02
Octhilinone [ANSI:BSI:ISO]
Octhilinone 10 ?g/mL in Acetonitrile
Octhilinone 10 ng/?l in Acetonitrile
Octhilinone 10 ng/µl in Acetonitrile
Octhilinone-d17
Octyl-3(2H)-isothiazolone
Octyl-4-isothiazol-3-one
octylisothiazolinone
OR-0610
Pancil
Pancil T
Pancil-T
RH-893
Skane 8
Skane M 8
Skane M8
Skane M-8
UNII:4LFS24GD0V
UNII-4LFS24GD0V
Vinylzene IT 3000DIDP
Vinyzene IT 3000DIDP
1211137 [DBID]
46078_RIEDEL [DBID]
BRN 1211137 [DBID]
Caswell No. 613C [DBID]
CCRIS 6082 [DBID]
EPA Pesticide Chemical Code 099901 [DBID]
NCGC00091875-01 [DBID]
RH 893 [DBID]