PRODUCTS

3-AMINOPROPYLTRIETHOXYSILANE

CAS Number: 919-30-2
EC Number: 213-048-4
IUPAC Name: 3-triethoxysilylpropan-1-amine
Chemical Formula: C9H23NO3Si

Other names: (3-Aminopropyl)triethoxysilane, (gamma-Aminopropyl)triethoxysilane, 1-Propanamine, 3-(triethoxysilyl)-, 3-(Triethoxysilyl)-1-propanamine, 3-(Triethoxysilyl)propylamine, 3-aminopropyltriethoxysilane, Nuca 1100, Propylamine, 3-(triethoxysilyl)-, Propylamine, 3-(triethoxysilyl)- (8CI), Silane 1100, Silane amg-9, Silane, (3-aminopropyl)triethoxy-, Silane, gamma-aminopropyltriethoxy-, Silicone A-1100, Triethoxy(3-aminopropyl)silane, Uc-A 1100, 3-aminopropyltriethoxysilane, AGM-9, Amino-propyl-triethoxysilane, APTES, (3-aminopropyl)tri(etoxy)silán (sk), (3-aminopropylo)trietoksysilan (pl), 3-(trietossisilil)-1-propanamina (it), 3-aminopropiltrietoksisilan (hr), 3-aminopropiltrietoksisilan (sl), 3-aminopropiltrietoksisilanas (lt), 3-aminopropiltrietoksisilāns (lv), 3-aminopropiltrietoxisilan (ro), 3-aminopropiltrietoxisilano (es), 3-aminopropiltrietoxiszilán (hu), 3-aminopropiltrietóxissilano (pt), 3-aminopropyltriethoxysilaan (nl), 3-aminopropyltriethoxysilan (cs), 3-aminopropyltriethoxysilan (da), 3-Aminopropyltriethoxysilan (de), 3-aminopropyltrietoksysilan (no), 3-aminopropyltrietoxisilan (sv), 3-aminopropyltriéthoxysilane (fr), 3-Aminopropyylitrietoksisilaani (fi), 3-aminopropüültrietoksüsilaan (et), 3-amminopropiltrietossisilano (it), 3-αμινοπροπυλοτριαιθοξυσιλάνιο (el), 3-аминопропилтриетоксисилан (bg), 1-Propanamine, 3-(triethoxysilyl)-, (3-aminopropyl)triethoxysilane, 1-Propanamine, 3-(triethoxysilyl)-, 1-Propylamine, 3-(triethoxysilyl)-, 3-(Triethoxysilyl) propylamine, 3-(Triethoxysilyl)-1-propanamine, 3-(Triethoxysilyl)-propylamin, 3-(Triethoxysilyl)propan-1-amine, 3-(triethoxysilyl)propan-1-amine, 3-(triethoxysilyl)propan-1-amine, partialy polymerized, 3-aminopropyl-triethoxysilane, 3-Aminopropyltriethoxysilan, 3-AMINOPROPYLTRIETHOXYSILANE, 3-Aminopropyltriethoxysilane, 3-aminopropyltriethoxysilane, 3-aminopropyltriethoxysilane, 3-Triethoxysilylpropan-1-amine, 3-triethoxysilylpropan-1-amine, 3-Triethoxysilylpropylamine, aminopropylalkoxysilane, Aminopropyltriethoxysilane, Aminopropyltriethoxysilane, aminopropyltriethoxysilane, aminosilane, APTES, APTS, Damsil 1350, gamma-Aminopropyltriethoxy silane, gamma-Aminopropyltriethoxysilane, silane, triethoxysilylpropan-1-amine, (3-Aminopropyl)triethoxysilane, 3-Aminopropyltriethoxysilane, APTES, BRB Silanil 919, CG-550, coupling agent, DOW CORNING(R) Z-6011, DOW CORNING(R) Z-6011 SILANE, Dynasylan(R) AMEO, Dynasylan(R) AMEO T, JH-A110, KH-550, Organosilane A302, SG-Si1100, SILQUEST A-1100 SILANE, SILQUEST A-1100 Silane A-1100 A 1100; A 1112; AGM 9; UC-A 1100; Aktisil AM; AMEO; Silane 1100; APTES; Dynasylan AMEO Dynasylan AMEO-P Prosil 220; CA750 NUCA 1100;, SILQUEST A-1102 SILANE, XIAMETER(R) OFS-6011, aminopropyltriethoxysilane, 1020103-34-7, 1020103-34-7, 1044532-60-6, 1044532-60-6, 106096-79-1, 106096-79-1, 12738-50-0, 12738-50-0, 130730-84-6, 130730-84-6, 131641-77-5, 131641-77-5, 1392103-81-9, 1392103-81-9, 143178-71-6, 143178-71-6, 159778-17-3, 159778-17-3, 1686133-96-9, 1686133-96-9, 204987-58-6, 3-Aminopropyltriethoxysilane, 919-30-2, (3-Aminopropyl)triethoxysilane, APTES, 3-(TRIETHOXYSILYL)PROPYLAMINE, 1-Propanamine, 3-(triethoxysilyl)-, 3-(triethoxysilyl)propan-1-amine, Propylamine, 3-(triethoxysilyl)-, gamma-Aminopropyltriethoxysilane, 3-Triethoxysilylpropylamine, Nuca 1100, Silicone A-1100, Silane 1100, Aminopropyltriethoxysilane, Triethoxy(3-aminopropyl)silane, 3-triethoxysilylpropan-1-amine, 3-(Triethoxysilyl)-1-propanamine, Uc-A 1100, Silane, (3-aminopropyl)triethoxy-, AGM-9, AGM 9, NSC 95428, A 1100, A 1112, 3-triethoxysilyl-1-propanamine, Triethoxyaminopropylsilane, (.gamma.-Aminopropyl)triethoxysilane, 3-AMINOPROPYL-TRIETHOXYSILANE, Triethoxy-3-aminopropylsilane, L8S6UBW552, 3-(Triethoxysilyl)-1-propylamine, MFCD00008207, NSC-95428, Silane, (.gamma.-aminopropyl)triethoxy-, Silane amg-9, (gamma-Aminopropyl)triethoxysilane, MFCD01324904, Dynasylan AMEO, (aminopropyl)triethoxysilane, CAS-919-30-2, Hydrosil 2627, Prosil 220, Silicone A 1100, HSDB 5767, Aminopropyltriethoxysilane(KH550), Silane, gamma-aminopropyltriethoxy-, aminopropyl triethoxysilane, EINECS 213-048-4, amino-propyl-triethoxysilane, BRN 1754988, UNII-L8S6UBW552, 3-aminopropyl triethoxysilane, gamma-triethoxysilylpropylamine, A 1102 (silane derivative), (3-Aminopropyl)triethoxylsilane, Dynasylan AMEO-P, Silsoft A-1100, aminopropyltriethoxy silane, Union Carbide A-1100, 3-Aminopropltriethoxysilane, aminopropyl triethoxy silane, EC 213-048-4, 3-aminopropytriethoxy silane, 3-aminopropyltriethoxylsilane, NCIOpen2_007962, 3-aminopropyltriethoxy silane, 3-aminopropyltriethoxy-silane, C 50752, SCHEMBL18080, (3-triethoxysilyl)propylamine, 4-04-00-04273 (Beilstein Handbook Reference), 3-aminopropyl(triethoxy)silane, 3-(triethoxysilyl) propylamine, 3-(triethoxysilyl)-propylamine, (3-aminopropyl)-triethoxysilane, gamma-aminopropyl-triethoxysilane, CHEMBL1542365, DTXSID2027333, gamma-Aminopropyltriethoxy silane, Xiameter(R) OFS-6011 silane, gamma-aminopropyl triethoxy silane, (C2H5O)3Si(CH2)3NH2, Aminopropyl triethoxysilane [INCI], HY-D0175, NSC95428, WLN: Z3-SI-O2&O2&O2, Tox21_201446, Tox21_303330, BBL027698, STK802166, (3-Aminopropyl)triethoxysilane, 99%, 3-(Triethoxysilyl)propylamine [HSDB], AKOS008901315, ZINC169743031, .GAMMA.-AMINPROPYLTRIETHOXYSILANE, .GAMMA.-TRIETHOXYSILYLPROPYLAMINE, (3-Aminopropyl)triethoxysilane, >=98%, NCGC00090985-01, NCGC00090985-02, NCGC00090985-03, NCGC00257040-01, NCGC00258997-01, AS-14523, BP-31043, (3-Aminopropyl)triethoxysilane, >=98.0%, DB-028361, A0439, CS-0010101, FT-0615063, D72483, EN300-371067, S00800, A844104, Q-200014, Q4542878, 3-(Triethoxysilyl)-1-propylamine 100 microg/mL in Acetonitrile, (3-Aminopropyl)triethoxysilane, packaged for use in deposition systems, >=98%, 3-Aminopropyltriethoxysilane, 98%, contained in 50 ml Swagelok? cylinder for CVD/ALD, (3-Aminopropyl)triethoxysilane [Wiki], (γ-Aminopropyl)triethoxysilane, 1-Propanamine, 3- (triethoxysilyl)-, 1-Propanamine, 3-(triethoxysilyl)- [ACD/Index Name], 213-048-4 [EINECS], 3-(Triethoxysilyl)-1-propanamin [German] [ACD/IUPAC Name], 3-(Triethoxysilyl)-1-propanamine [ACD/IUPAC Name], 3-(Triéthoxysilyl)-1-propanamine [French] [ACD/IUPAC Name], 3-(triethoxysilyl)propan-1-amine, 3-(Triethoxysilyl)propylamine, 3-aminopropyl triethoxysilane, 3-aminopropyl(triethoxy)silane, 3-aminopropyltriethoxy silane, 3-aminopropyl-triethoxysilane, 3-Aminopropyltriethoxysilane, 3-Triethoxysilylpropylamine, 919-30-2 [RN], Aminopropyltriethoxysilane, APTES, APTS, L8S6UBW552, MFCD00008207 [MDL number], Propylamine, 3- (triethoxysilyl)-, Silane, (γ-aminopropyl)triethoxy-, γ-Aminopropyltriethoxy silane, γ-aminopropyltriethoxysilane, (3-aminopropyl)triethoxysilane, (3-Aminopropyl)triethoxysilane; 3-Triethoxysilylpropylamine; APTES; APTS, (3-Triethoxysilylpropylamine), (γ-Aminopropyl)triethoxysilane, 29159-37-3 [RN], 3-aminopropyltriethoxysilane, 3-(Triethoxysilyl)propan-1-amin, 3-(Triethoxysilyl)-propylamine, 3-amino propyl triethoxysilane, 3-aminopropyl triethoxy silane, 3-aminopropyl(triethoxyl)silane, 3-Aminopropyltriethoxysilan, 3-aminopropyltriethoxy-silane, 3-amino-propyltriethoxysilane, 3-triethoxysilyl-1-propanamine, 3-triethoxysilylpropan-1-amine, 4-04-00-04273 [Beilstein], aminopropyl triethoxysilane, aminopropyltriethoxy silane, aminopropyl-triethoxysilane, amino-propyl-triethoxy-silane, Aminopropyltriethoxysilane(KH550), NCGC00090985-02, Propylamine, 3-(triethoxysilyl)-, Propylamine, 3-(triethoxysilyl)- (8CI), Prosil 220, Silane, (3-aminopropyl)triethoxy-, silane, 3-aminopropyltriethoxy-, Silane, γ-aminopropyltriethoxy-, Triethoxy(3-aminopropyl)silane, Triethoxyaminopropylsilane, Uc-A 1100, UNII-L8S6UBW552, Z3-SI-O2&O2&O2 [WLN], γ-aminopropyl triethoxysilane, γ-aminopropyltriethoxysilane

3-Aminopropyltriethoxysilane is an aminosilane frequently used in the process of silanization, the functionalization of surfaces with alkoxysilane molecules.
3-Aminopropyltriethoxysilane can also be used for covalent attaching of organic films to metal oxides such as silica and titania.

Use with PDMS of 3-Aminopropyltriethoxysilane
3-Aminopropyltriethoxysilane can be used to covalently bond thermoplastics to poly(dimethylsiloxane) (PDMS).
Thermoplastics are treated with oxygen plasma to functionalize surface molecules, and subsequently coated with an aqueous 1% by volume 3-Aminopropyltriethoxysilane solution.
3-Aminopropyltriethoxysilane is treated with oxygen plasma and placed in contact with the functionalized thermoplastic surface.
A stable, covalent bond forms within 2 minutes.

Silsesquioxane synthesis of 3-Aminopropyltriethoxysilane
3-Aminopropyltriethoxysilane can be obtained in a one step hydrolytic condensation using APTES and hydrochloric or trifluoromethanesulfonic acid (CF3SO3H).

Use with cell cultures of 3-Aminopropyltriethoxysilane
3-Aminopropyltriethoxysilane-functionalized surfaces have been shown to be nontoxic to embryonic rat cardiomyocytes in vitro.
Further experimentation is needed to evaluate toxicity to other cell types in extended culture.

Toxicity of 3-Aminopropyltriethoxysilane
3-Aminopropyltriethoxysilane is a toxic compound with an MSDS health hazard score of 3.
3-Aminopropyltriethoxysilane fumes are destructive to the mucous membranes and the upper respiratory tract, and should be used in a fume hood with gloves.
If a fume hood is not available, a face shield and full face respirator must be implemented.
The target organs of 3-Aminopropyltriethoxysilane are nerves, liver and kidney.

Use and Manufacturing of 3-Aminopropyltriethoxysilane
Used to size glass fibers for making laminates and to make non-thrombogenic dental and orthopedic materials; Used as coupling agent and adhesion promoter in fiberglass, adhesives, sealants, foundry resins, and coatings
Used as coupling agents and adhesion promoters, aminosilanes are intentionally converted by hydrolysis to the trisilanols, which then bond molecularly to inorganic substrates
The commercial uses of this material are numerous and include various applications as coupling agents and adhesion promoters in fiberglass, adhesives and sealants, foundry resins, and in pre-treatment for coatings. A small percentage of this material may be found in sealants and coatings.

Industry Uses of 3-Aminopropyltriethoxysilane
Adhesion/cohesion promoter
Adhesives and sealant chemicals
Intermediate
Intermediates
Paint additives and coating additives not described by other categories
Plating agents and surface treating agents

General Manufacturing Information
Industry Processing Sectors
Adhesive Manufacturing
All Other Basic Inorganic Chemical Manufacturing
All Other Chemical Product and Preparation Manufacturing

Computer and Electronic Product Manufacturing
Construction
Miscellaneous Manufacturing
Paint and Coating Manufacturing
Plastics Product Manufacturing
Synthetic Rubber Manufacturing

Features of 3-Aminopropyltriethoxysilane:
Crosslinking agents such as BS3, EDC and Sulfo-SMCC can be used to immobilize proteins, peptides, modified DNA, etc., to the treated surface
Coats certain plastic surfaces noncovalently to create a reactive film
Chemically adheres tissue sections to glass slides for immunohistochemistry

3-Aminopropyltriethoxysilane is a surface treatment used to chemically couple various ligands to glass or silica surfaces such as glass slides.
3-Aminopropyltriethoxysilane is first coupled to glass or silica through the silane.
Compounds of interest are then coupled to the newly added amino groups directly, or additional chemistries are applied using the amino function prior to coupling.

The use of the coupling agent, 3-Aminopropyltriethoxysilane, in the silanization reaction with silanol-terminated silicon is an important surface modification reaction.
Of particular importance is that the terminal amine functionalities of 3-Aminopropyltriethoxysilane are sufficiently exposed to the gas or liquid phase for further modifications, such as amide coupling reactions.

3-Aminopropyltriethoxysilane is a silane widely used to supply amino groups for further modifications on various materials, but it is less studied as a catalyst to catalyze sol–gel silica polymerization.
Here, by using 3-Aminopropyltriethoxysilane as the catalyst instead of the conventional basic catalysts, a novel strategy was developed to prepare silica-based molecularly imprinted polymers (MIPs).

3-Aminopropyltriethoxysilane is useful in the formation of aminopropyl derivative of glass.
3-Aminopropyltriethoxysilane acts as an adsorbent for affinity chromatography.
3-Aminopropyltriethoxysilane is used to prepare positively charged slides suitable for use with various immunohistochemical and in situ hybridization procedures.
In addition, 3-Aminopropyltriethoxysilane is used as adhesives and sealant chemicals, paint additives and coating additives.
Further, 3-Aminopropyltriethoxysilane is used as a silylation reagent for coating glass and silica surfaces and to crosslink and immobilize proteins and other molecules.

Applications of 3-Aminopropyltriethoxysilane
3-Aminopropyltriethoxysilane is useful in the formation of aminopropyl derivative of glass.
3-Aminopropyltriethoxysilane acts as an adsorbent for affinity chromatography.
3-Aminopropyltriethoxysilane is used to prepare positively charged slides suitable for use with various immunohistochemical and in situ hybridization procedures.
In addition, 3-Aminopropyltriethoxysilane is used as adhesives and sealant chemicals, paint additives and coating additives.
Further, 3-Aminopropyltriethoxysilane is used as a silylation reagent for coating glass and silica surfaces and to crosslink and immobilize proteins and other molecules.

Use of 3-Aminopropyltriethoxysilane:
3-Aminopropyltriethoxysilane is a bifunctional silane possessing a reactive primary amino group and hydrolyzable ethoxysilyl groups.
The dual nature of its reactivity allows 3-Aminopropyltriethoxysilane to act as adhesive promoter between inorganic materials (i.e. glass, metals, fillers) and organic polymers (i.e. thermosets, thermoplastics, elastomers).
3-Aminopropyltriethoxysilane can also work as surface modifier.
3-Aminopropyltriethoxysilane is a colorless to slightly yellowish low-viscosity liquid with an amine-like odor.
3-Aminopropyltriethoxysilane is soluble in alcohols, and aliphatic or aromatic hydrocarbons.

Applications of 3-Aminopropyltriethoxysilane
3-Aminopropyltriethoxysilane is the isotope labelled analog of 3-Aminopropyltriethoxysilane (A628785); a reagent in the preparation of ultrastable organic dye nanoparticles in living cells.
Also used in the preparation of monoclonal antibody-functionalized mesoporous silica nanaoparticles packaged with Mifepristone (M343975), a progesterone receptor antagonist with partial agonist activity.
Abortifacient.

Feature of 3-Aminopropyltriethoxysilane:
Amino reactive activity.
Improve the mechanical properties of composite materials.
Improve compatibility between inorganic filler and polymer.

Application of 3-Aminopropyltriethoxysilane:
Composite Material:
3-Aminopropyltriethoxysilane is widely used in composite materials to improve the compatibility of inorganic filler and polymer in composite materials.
The mechanical properties, such as tensile and bending resistance, as well as thermal properties, electrical properties and water resistance, etc. of the composites are significantly improved.
Especially suitable for all kinds of glass fiber reinforced thermoplastic and thermosetting resins.

Resin Modified:
3-Aminopropyltriethoxysilane can be used as the raw material of a new generation of amino modified silicone oil and a variety of silicone super soft finishing agents.

Adhesive:
3-Aminopropyltriethoxysilane used in nitrile - phenolic structural adhesive, polyethylene butanaldehyde - phenolic adhesive, polyurethane adhesive hot melt adhesive, add 1% of the solid content or less, can make the bond strength increased by 60% to 100%.
Add this sealant to polyurethane sealant and plastic-melt sealant to obtain long-term adhesion to glass, masonry, metal and other substrates, and have excellent stability and high elongation to the climate.

Coating/Ink:
3-Aminopropyltriethoxysilane can be used in coating, ink as an adhesive enhancer to improve adhesion, reduce curing temperature, improve weather resistance, etc.

Casting Resin Industry:
3-Aminopropyltriethoxysilane can be used in the casting industry to reduce the amount of resin in silica sand, improve the strength of mold sand (about 30%) and reduce gas production.

Magnetic Material:
3-Aminopropyltriethoxysilane used in magnetic materials can improve the dispersion and adhesion of the plastic magnetic and rubber magnetic particles in organic compound, so that the magnetic particles have a higher orientation.
So that it can obtain better magnetic properties, improve the mechanical strength and weather resistance of magnetic materials, also easy to dry and easy to process.

Uses of 3-Aminopropyltriethoxysilane
3-Aminopropyltriethoxysilane is a versatile amino-functional coupling agent used over a broad range of applications to provide superior bonds between inorganic substrates and organic polymers.
The silicon-containing portion of the molecule provides strong bonding to substrates.
The primary amine function reacts with a wide array of thermoset, thermoplastic, and elastomeric materials.

Silane coupling agent 3-Aminopropyltriethoxysilane is applied in plastic products (including cables, glassfiber-reinforcement plastics etc.), rubber products, adhesives, coatings, pigments dispersion, inks, magnetic materials (plastic magnet and rubber magnet), metallic casting resins and resins concrete, etc.

3-Aminopropyltriethoxysilane maximizes the physical and electrical properties of mineral-filled phenolics, epoxies, polyamides, polybutylene terephthalate, and a host of other thermoset and thermoplastic composites. Filler wetting and dispersibility in the polymer matrix are also improved.
3-Aminopropyltriethoxysilane improves adhesion between magnetic powder and organic resins and dispersion of magnetic powder inorganic resins.
Also these magnetic appliances attain higher magnetic orientation and excellent magnetic properties, higher mechanical strength, good processability, excellent weathering resistance.

In glass-reinforced thermoset plastics, 3-Aminopropyltriethoxysilane enhances the flexural, compressive, and interlaminar shear strengths before and after exposure to humidity.
3-Aminopropyltriethoxysilane greatly improves wet electrical properties.
With nitrile, polysulfide, expoxy, urethane, and adhesives and sealants, 3-Aminopropyltriethoxysilane improves pigment dispersion and maximizes adhesion to glass, aluminum, and steel.
When 3-Aminopropyltriethoxysilane is used, glass-reinforced thermoplastics, polyamides, polyesters, and polycarbonates exhibit increased flexural and tensile strengths before and after wet exposure.

In glass fiber and mineral wool insulation, as a phenolics resin binder additive, 3-Aminopropyltriethoxysilane imparts moisture resistance and allows recovery after compression.
In shell molding foundry applications, 3-Aminopropyltriethoxysilane strengthens the bond between the phenolics binder and foundry sand.
In grinding wheels, 3-Aminopropyltriethoxysilane promotes an improved, water-resistant bond between the abrasive grit and phenolics resin binder.
3-Aminopropyltriethoxysilane is an excellent adhesion prompter in urethane, epoxy, and acrylic latex coatings, adhesives, and sealants.

Uses of 3-Aminopropyltriethoxysilane
3-Aminopropyltriethoxysilane is useful in the formation of aminopropyl derivative of glass.
3-Aminopropyltriethoxysilane acts as an adsorbent for affinity chromatography.
3-Aminopropyltriethoxysilane is used to prepare positively charged slides suitable for use with various immunohistochemical and in situ hybridization procedures.

In addition, 3-Aminopropyltriethoxysilane is used as adhesives and sealant chemicals, paint additives and coating additives.
Further, 3-Aminopropyltriethoxysilane is used as a silylation reagent for coating glass and silica surfaces and to crosslink and immobilize proteins and other molecules.

Applications of 3-Aminopropyltriethoxysilane：
Coatings, Adhesives and Sealants
The aminosilane is an excellent adhesion promoter in acrylic coatings, adhesives and sealants.
With polysulfide, urethane, RTV silicones, epoxy, nitrile, phenol formaldehyde resin, adhesives and sealants, the product improves pigment dispersion and maximizes adhesion to glass, aluminum and steel.

Fiber glass Reinforcement
In fiberglass reinforced thermosetting plastics and thermoplastics, the 3-Aminopropyltriethoxysilane enhances the flexural, tensile and interlaminar shearing strengths before and after exposure to humidity.
3-Aminopropyltriethoxysilane greatly improves wet electrical properties.
Fiberglass reinforced thermoplastics, polyamides, polyesters and polycarbonates exhibit increased flexural and tensile strengths before and after wet exposure when this silane is used.

Glass Fiber and Mineral Wool Insulation
As a phenolic resin binder additive, the 3-Aminopropyltriethoxysilane imparts moisture resistance and allows recovery after compression

Mineral Filler and Resin Systems
The aminosilane maximizes the physical and electrical properties of mineral-filled phenolics, polyester resin, epoxies, polyamides, polycarbonate and a host of other thermoset and thermoplastic composites.
Wettability and dispersibility of filler in the polymer matrix are also improved.

Foundry Application
In shell molding, the aminosilane strengthens the bond between the phenolic binder and foundry sand.

Grinding Wheel Manufacture
The aminosilane promotes an improved, water resistant bond between the abrasive grit and phenolic resin binder.

Wood plastic composite production
The mechanical properties of composites made of wood meal, such as impact strength, bending strength and bending modulus, will be improved after these composites are processed with this product.

Hazard classification & labelling of 3-Aminopropyltriethoxysilane
Danger! According to the harmonised classification and labelling (CLP00) approved by the European Union, 3-Aminopropyltriethoxysilane causes severe skin burns and eye damage and is harmful if swallowed.
Additionally, the classification provided by companies to ECHA in REACH registrations identifies that 3-Aminopropyltriethoxysilane causes serious eye damage and may cause an allergic skin reaction.

About 3-Aminopropyltriethoxysilane
3-Aminopropyltriethoxysilane is registered under the REACH Regulation and is manufactured in and / or imported to the European Economic Area, at ≥ 1 000 to < 10 000 tonnes per annum.
3-Aminopropyltriethoxysilane is used by consumers, in articles, by professional workers (widespread uses), in formulation or re-packing, at industrial sites and in manufacturing.

Consumer Uses of 3-Aminopropyltriethoxysilane
3-Aminopropyltriethoxysilane is used in the following products: adhesives and sealants and coating products.
Other release to the environment of 3-Aminopropyltriethoxysilane is likely to occur from: indoor use (e.g. machine wash liquids/detergents, automotive care products, paints and coating or adhesives, fragrances and air fresheners) and outdoor use.

Release to the environment of 3-Aminopropyltriethoxysilane can occur from industrial use: industrial abrasion processing with low release rate (e.g. cutting of textile, cutting, machining or grinding of metal) and of articles where the substances are not intended to be released and where the conditions of use do not promote release. Other release to the environment of 3-Aminopropyltriethoxysilane is likely to occur from: outdoor use in long-life materials with low release rate (e.g. metal, wooden and plastic construction and building materials) and indoor use in long-life materials with low release rate (e.g. flooring, furniture, toys, construction materials, curtains, foot-wear, leather products, paper and cardboard products, electronic equipment).
ECHA has no public registered data indicating whether or into which articles the substance might have been processed.

Widespread uses by professional workers
3-Aminopropyltriethoxysilane is used in the following products: adhesives and sealants, coating products and laboratory chemicals.
3-Aminopropyltriethoxysilane is used in the following areas: building & construction work and formulation of mixtures and/or re-packaging.
3-Aminopropyltriethoxysilane is used for the manufacture of: machinery and vehicles, furniture, plastic products, mineral products (e.g. plasters, cement), wood and wood products, fabricated metal products, electrical, electronic and optical equipment, textile, leather or fur and pulp, paper and paper products.

Release to the environment of 3-Aminopropyltriethoxysilane can occur from industrial use: formulation of mixtures.
Other release to the environment of 3-Aminopropyltriethoxysilane is likely to occur from: indoor use (e.g. machine wash liquids/detergents, automotive care products, paints and coating or adhesives, fragrances and air fresheners) and outdoor use.

Formulation
3-Aminopropyltriethoxysilane is used in the following products: coating products, adhesives and sealants, non-metal-surface treatment products, polymers and oil and gas exploration or production products.
Release to the environment of 3-Aminopropyltriethoxysilane can occur from industrial use: formulation of mixtures, in the production of articles and formulation in materials.
Other release to the environment of 3-Aminopropyltriethoxysilane is likely to occur from: indoor use (e.g. machine wash liquids/detergents, automotive care products, paints and coating or adhesives, fragrances and air fresheners) and outdoor use.

Uses at industry
3-Aminopropyltriethoxysilane is used in the following products: oil and gas exploration or production products, coating products, non-metal-surface treatment products, adhesives and sealants and laboratory chemicals.
3-Aminopropyltriethoxysilane has an industrial use resulting in manufacture of another substance (use of intermediates).
3-Aminopropyltriethoxysilane is used in the following areas: mining and building & construction work.

3-Aminopropyltriethoxysilane is used for the manufacture of: chemicals, mineral products (e.g. plasters, cement), machinery and vehicles and plastic products.
Release to the environment of 3-Aminopropyltriethoxysilane can occur from industrial use: in the production of articles, as an intermediate step in further manufacturing of another substance (use of intermediates), for thermoplastic manufacture, as processing aid, as processing aid, of substances in closed systems with minimal release, formulation of mixtures and in processing aids at industrial sites.

Release to the environment of 3-Aminopropyltriethoxysilane can occur from industrial use: manufacturing of the substance, for thermoplastic manufacture and as an intermediate step in further manufacturing of another substance (use of intermediates).