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3-Mercaptopropionic acid (3-MPA) is an organosulfur compound with the formula HSCH2CH2CO2H.
3-Mercaptopropionic acid (3-MPA) is a bifunctional molecule, containing both carboxylic acid and thiol groups.
3-Mercaptopropionic acid (3-MPA) is a colorless oil.
3-Mercaptopropionic acid (3-MPA) is derived from the addition of hydrogen sulfide to acrylic acid.
CAS Number: 107-96-0
EC Number: 203-537-0
IUPAC Name: 3-Sulfanylpropanoic acid
Chemical Formula: C3H6O2S
Other names: 107-96-0, 3-Sulfanylpropanoic acid, 3-Thiopropionic acid, beta-Mercaptopropionic acid, 3-Thiopropanoic acid, Mercaptopropionic acid, Propanoic acid, 3-mercapto-, 3MPA, beta-Thiopropionic acid, Propionic acid, 3-mercapto-, 2-Mercaptoethanecarboxylic acid, Hydracrylic acid, 3-thio-, beta-Mercaptopropanoic acid, Thiohydracrylic acid, UNII-B03TJ3QU9M, NSC 437, 3-Thiolpropanoic acid, 3-thiohydracrylic acid, 3-Mercaptopropionicacid, 3-mercapto-propionic acid, MFCD00004897, .beta.-Thiopropionic acid, B03TJ3QU9M, .beta.-Mercaptopropionic acid, CHEMBL358697, CHEBI:44111, Propionic acid, 3-mercpato-, HSDB 5381, 3 Mercaptopropionic Acid, EINECS 203-537-0, BRN 0773807, AI3-26090, BMPA, ss--Thiopropionic acid, 3-mercaptopropanic acid, Sugammadex Impurity 60, betamercaptopropionic acid, 3-mercapto-propanoic acid, DSSTox_CID_6775, ss--Mercaptopropanoic acid, ss--Mercaptopropionic acid, EC 203-537-0, 3-Sulfanylpropanoic acid #, SCHEMBL7289, DSSTox_RID_78211, DSSTox_GSID_26775, .beta.-Mercaptopropanoic acid, 4-03-00-00726 (Beilstein Handbook Reference), 3-Mercaptopropanoic acid, 9CI, NSC437, 3-Mercaptopropionic acid, 98%, DTXSID8026775, NSC-437, 3-Mercaptopropionic acid, >=99%, AMY27767, BCP16636, STR01222, ZINC3860582, Tox21_200194, 7053AF, BDBM50121953, STL281859, Thiopropionic acid; 3-Thiopropanoic acid; beta-Mercaptopropionic acid, AKOS000121541, AC-4722, AT21041, MCULE-3211932163, SB66313, NCGC00248556-01, NCGC00257748-01, BP-21405, CAS-107-96-0, FT-0615955, FT-0658630, M0061, 3-Mercaptopropionic acid, >=99.0% (HPLC), Propanoic acid, 3-mercapto-, coco alkyl esters, 3-Dimethylamino-2-methylpropylchloridehydrochloride, A801785, J-512742, Q11751618, F2191-0215, 68307-97-1, 3-mercaptopropionic acid, 3-mercaptopropionic acid, Propanoic acid, 3-mercapto-, 3-Mercaptopropanoic acid, 3-MERCAPTOPROPIONIC ACID, 3-Mercaptopropionic Acid, 3-Mercaptopropionic acid, 3-mercaptopropionic acid, 3-Mercaptopropionsäure, 3-sulfanylpropanoic acid, MPA, Propanoic acid, 3-mercapto-, Propanoic acid, 3-mercapto-, β-Mercaptopropionic acid, 3-mercaptopropionic acid 80%, 3-mercaptopropionic acid 80% EC, 3-mercaptopropionic acid 99%, 3-mercaptopropionic acid 99% EC, 3-MPA, 3-MPS, MPA, MPS, Propanoic acid, 3-mercapto-, 3-Mercaptopropionic acid, 107-96-0 [RN], 203-537-0 [EINECS], 2-mercaptoethanecarboxylic acid, 3-mercaptopropanoic acid, 3-Sulfanylpropanoic acid [ACD/IUPAC Name], 3-Sulfanylpropansäure [German] [ACD/IUPAC Name], 3-thiopropionic acid, 4-03-00-00726 [Beilstein], 773807 [Beilstein], Acide 3-sulfanylpropanoïque [French] [ACD/IUPAC Name], B03TJ3QU9M, Hydracrylic acid, 3-thio-, mercaptopropionic acid, MFCD00004897 [MDL number], Propanoic acid, 3-mercapto- [ACD/Index Name], SH2VQ [WLN], UF5270000, UNII-B03TJ3QU9M, β-Mercaptopropanoic acid, β-mercaptopropionic acid, β-Mercaptopropionic acid, β-thiopropionic acid, β-Thiopropionic acid, ??-mercaptopropionic acid, 203-537-0MFCD00004897, 3-Mercapto Propionic Acid, 3-Mercaptopropanic Acid, 3-mercaptopropanoate, 3-mercapto-propanoic acid, 3-Mercaptopropanoic acid, 9CI, 3-Mercaptopropionic acid-, 3-Mercapto-propionic acid, 3-Mercaptopropionic Acid (en), 3MPA, 3-MPA, 3-thiohydracrylic acid, 3-thiolpropanoic acid, 3-Thiopropanoic acid, Benzoic acid, 4-(aminomethyl)- (9CI), propionic acid, 3-mercapto-, propionic acid, mercapto-, ß-mercaptopropionic acid, STR01222, T5SJ B1 C1 DVQ E- AT5NJ [WLN], Thiohydracrylic acid, UNII:B03TJ3QU9M, β-Mercaptopropanoic acid, β-Mercaptopropionate, β-mercaptopropionic acid
Reactions and uses of 3-Mercaptopropionic acid (3-MPA)
3-Mercaptopropionic acid (3-MPA) is competitive inhibitor of glutamate decarboxylase, and therefore acts as a convulsant.
3-Mercaptopropionic acid (3-MPA) has higher potency and faster onset of action compared to allylglycine.
3-Mercaptopropionic acid (3-MPA) is used to prepare hydrophilic gold nanoparticles, exploiting the affinity of gold for sulfur ligands.
3-Mercaptopropionic acid (3-MPA) is a natural product found in Synechococcus elongatus and Bos taurus with data available.
3-Mercaptopropionic acid (3-MPA) is a mercaptopropanoic acid that is propanoic acid carrying a sulfanyl group at position 3.
3-Mercaptopropionic acid (3-MPA) has a role as an algal metabolite.
3-Mercaptopropionic acid (3-MPA) is a conjugate acid of a 3-mercaptopropionate.
An inhibitor of glutamate decarboxylase.
3-Mercaptopropionic acid (3-MPA) decreases the GAMMA-AMINOBUTYRIC ACID concentration in the brain, thereby causing convulsions.
Use and Manufacturing of 3-Mercaptopropionic acid (3-MPA)
Used as a stabilizer, antioxidant, catalyst, chemical intermediate, and experimental convulsant agent; [HSDB]
Industry Uses of 3-Mercaptopropionic acid (3-MPA)
-Intermediates
-Process regulators
Consumer Uses of 3-Mercaptopropionic acid (3-MPA)
-Building/construction materials not covered elsewhere
General Manufacturing Information
Industry Processing Sectors
-All other chemical product and preparation manufacturing
-Plastic material and resin manufacturing
3-Mercaptopropionic acid (3-MPA) is used as a self-assembled monolayer (SAM) with a thiol and carboxylic groups.
3-Mercaptopropionic acid (3-MPA) has short carbon chains and is mainly used as a capping agent on a variety of nanoparticles.
Application of 3-Mercaptopropionic acid (3-MPA)
3-MPA is used to produce hydrophilic SAMs, which are terminated with carboxylic acids and can be further functionalized to introduce more complex end groups such as enzymes for biosensor applications.
SAMs of 3-MPA are capped on ZnSe quantum dots for the electrochemical detection of dopamine.
3-MPA is used as a capping agent on CdTe quantum dot nanocrystals (QD NCs) for use as labeling materials in biomedical applications.
3-Mercaptopropionic acid (3-MPA) can also be used to modify the surface of iron oxide nanoparticles (Fe2O3) in the extraction and preconcentration of Al3+ and Cr3+ ions from different biological samples.
3-Mercaptopropionic acid (3-MPA) is widely used in food and beverage industries as a flavoring agent.
3-Mercaptopropionic acid (3-MPA) is used in the production of PVC stabilizers, which are used as chain transfer agents in polymerizations.
3-Mercaptopropionic acid (3-MPA) can be used as primary or secondary, color stabilizer in combination with phenolic antioxidant for polymers.
3-Mercaptopropionic acid (3-MPA) is widely used in food and beverage industries as a flavoring agent.
3-Mercaptopropionic acid (3-MPA) is used in the production of PVC stabilizers, which are used as chain transfer agents in polymerizations.
3-Mercaptopropionic acid (3-MPA) can be used as primary or secondary, color stabilizer in combination with phenolic antioxidant for polymers and can also be used as a chain transfer agent.
3-Mercaptopropionic acid (3-MPA) and its derivatives are main materials for the synthesis of PVC-stabilizers and are used as chain transfer and cross-linking agents in polymerizations.
These compounds are also useful as ion exchange catalysts, coupling agents, and in UV-curable formulations.
3-Mercaptopropionic acid (3-MPA) is a clear, near water-white liquid with strong odor used as a basic material in the production of PVC stabilizers.
3-Mercaptopropionic acid Usage：
-Construction field: Retarding polyester water reducing agent PCA and polyetherwater reducing agent PCE.
-Pharmaceutical field: 3-Mercaptopropionic acid is the intermediate of pharmaceutical Chlormezanone and is also used as a stabilizer of PVC.
-Like thioglycolic acid, it can be used in transparent products with excellent thermal stability and is superior to other stabilizers.
-It is also used as an antioxidant, catalyst and biochemical reagent.
3-Mercaptopropionic Acid [3-MPA] contains both carboxylic acid and thiol groups.
3 Mercaptopropionic Acid [3-MPA] is a colorless oil and derived from the addition of hydrogen sulfide to acrylic acid.
Application Area of 3-Mercaptopropionic Acid [3-MPA]:
-Pharmaceutical intermediate;
-Chain transfer agent for Polycarboxylate Superplasticizer
-Raw material for PVC tin stabilizers;
-Concrete admixture.
3-Mercaptopropionic acid (3-MPA) belongs to the family of mercaptans.
3-MPA is known for a long time and was already synthesized by Lovén in 1884.
All major chemical suppliers sell the compound for a reasonable price nowadays.
A convenient preparation is possible by the procedure of Gresham et al, who employed MPA for various organic syntheses.
This interesting bifunctional compound is also known as a versatile chain transfer reagent in the telomerization of short oligomers for biotechnological applications.
3-Mercaptopropionic acid (3-MPA) is useful in many different types of pharmaceutical processes, including as an enzyme inhibitor, GABA agent and convulsant; it is a flavoring agent in beverages and cheeses, and is also applied in the production of certain haircare products.
3-Mercaptopropionic acid (3-MPA) comes in the form of a clear to yellowish liquid, and crystallizes upon cooling.
Uses of 3-Mercaptopropionic acid (3-MPA)
3-Mercaptopropionic acid is widely used in food and beverage industries as a flavoring agent.
It is used in the production of PVC stabilizers, which are used as chain transfer agents in polymerizations.
It can be used as primary or secondary, color stabilizer in combination with phenolic antioxidant for polymers.
It acts as a sulfide ion equivalent and is utilized in the preparation of diaryl sulfide from aryl iodide.
FIRST AID MEASURES of 3-Mercaptopropionic acid (3-MPA)
If inhaled :
If breathed in, move person into fresh air.
If not breathing, give artificial respiration.
Consult a physician.
In case of skin contact :
Take off contaminated clothing and shoes immediately.
Wash off with soap and plenty of water.
Take victim immediately to hospital.
Consult a physician.
In case of eye contact :
Rinse thoroughly with plenty of water for at least 15 minutes and consult a physician.
Continue rinsing eyes during transport to hospital.
If swallowed :
Do NOT induce vomiting.
Never give anything by mouth to an unconscious person.
Rinse mouth with water.
Consult a physician.
Hazard classification & labelling of 3-Mercaptopropionic acid (3-MPA)
Danger! According to the classification provided by companies to ECHA in REACH registrations this substance is toxic if swallowed, causes severe skin burns and eye damage, causes serious eye damage, is harmful if inhaled and may be corrosive to metals.
3-Mercaptopropionic acid (3-MPA) is registered under the REACH Regulation and is manufactured in and / or imported to the European Economic Area, at ≥ 1 000 to < 10 000 tonnes per annum.
3-Mercaptopropionic acid (3-MPA) is used by professional workers (widespread uses), in formulation or re-packing, at industrial sites and in manufacturing.
3-Mercaptopropionic acid (3-MPA) is used in the following products: laboratory chemicals.
Other release to the environment of this substance is likely to occur from: indoor use.
Release to the environment of this substance can occur from industrial use: formulation of mixtures.
3-Mercaptopropionic acid (3-MPA) is used in the following products: polymers and pharmaceuticals.
3-Mercaptopropionic acid (3-MPA) is used in the following areas: building & construction work.
3-Mercaptopropionic acid (3-MPA) is used for the manufacture of: plastic products and rubber products.
Release to the environment of this substance can occur from industrial use: as processing aid, of substances in closed systems with minimal release and as an intermediate step in further manufacturing of another substance (use of intermediates).
Release to the environment of this substance can occur from industrial use: manufacturing of the substance.
