4-TERT-BUTYLCYCLOHEXANOL

4-tert-Butylcyclohexanol is a trademarked name for a specific ingredient used primarily in the cosmetic and personal care industry. 
4-tert-Butylcyclohexanol is known for its soothing and anti-inflammatory properties, which make it suitable for sensitive skin applications.
4-tert-Butylcyclohexanol is a white crystals, insoluble in water, soluble in alcohol. 

CAS Number: 21862-63-5
EC Number: 700-127-8
IUPAC Name: 4-tert-butylcyclohexan-1-ol
Molecular Formula: C10H20O

Other names: 4-tert-Butylcyclohexanol, 98-52-2, cis-4-tert-Butylcyclohexanol, 937-05-3, trans-4-tert-butylcyclohexanol, 21862-63-5, 4-(tert-Butyl)cyclohexanol, cis-4-(tert-Butyl)cyclohexanol, 4-tert-butylcyclohexan-1-ol, Cyclohexanol, 4-(1,1-dimethylethyl)-, trans-4-(tert-Butyl)cyclohexanol, Padaryl, p-tert-Butylcyclohexanol, Cyclohexanol, 4-(1,1-dimethylethyl)-, cis-, CYCLOHEXANOL, 4-tert-BUTYL-, 4-t-Butylcyclohexanol, USAF DO-20, Cyclohexanol, 4-(1,1-dimethylethyl)-, trans-, Cyclohexanol, 4-tert-butyl-, cis-, 4-tert-butyl-1-cyclohexanol, 4-tert-Butylcyclohexanol, cis-, F5FZ4Y0UMG, DTXSID5026623, cis-4-tert-butyl-1-cyclohexanol, 4-tert-Butylcyclohexanol, trans-, L5067JRJ73, (1s,4s)-4-tert-butylcyclohexanol, MFCD00001473, (1S,4S)-4-TERT-BUTYLCYCLOHEXAN-1-OL, DTXCID606623, 4-tert-Butyl cyclohexanol, CAS-98-52-2, EINECS 202-676-4, NSC 404197, BRN 1902277, UNII-K0H1405S9C, UNII-L5067JRJ73, AI3-02503, 4-(tert-butyl)cyclohexan-1-ol, trans-4-tert-Butyl-cyclohexanol, cis-4-tert-Butylcyclan-1-ol, EINECS 213-321-8, 3-XYLENEDIAMINE, 4-terbutyl-cyclohexanol, p-tert-butyl cyclohexanol, UNII-F5FZ4Y0UMG, 4-tert-butyl-cyclohexanol, Cis-4-t-butylcyclohexanol, 4-t-butyl-1-cyclohexanol, cis-4-tertbutylcyclohexanol, EC 202-676-4, 4-tert.-Butyl-cyclohexanol, cis-4-Tert-butylcyclhexanol, trans-4-t-butylcyclohexanol, Hexahydro-p-tert-butylphenol, cis 4-tert-Butylcyclohexanol, cis-4-(t-butyl)cyclohexanol, 4-tert-Butylcyclohexanol,c&t, 1-06-00-00018 (Beilstein Handbook Reference), cis 4-tert-Butyl-cyclohexanol, cis-4-tert-butyl cyclohexanol, cis-4-tert-Butyl-cyclohexanol, SCHEMBL114150, SCHEMBL579272, SCHEMBL579573, (E)-4-tert-Butylcyclohexanol, 4-tert-butyl-cyclohexan-1-ol, Cyclohexanol,1-dimethylethyl)-, cis-4-tert.-butyl-cyclohexanol, SCHEMBL7752973, SCHEMBL8365597, trans 4-tert-Butyl-cyclohexanol, trans-4-tert-butyl cyclohexanol, CHEMBL1886723, FEMA NO. 4724, 4-tert-Butylcyclohexanol, (Z)-, AMY3572, DTXSID40883571, DTXSID50885182, K0H1405S9C, (1r,4r)-4-tert-butylcyclohexanol, BCP30881, inverted exclamation markY95%(GC), STR03673, WAA86263, 4-CIS-TERT-BUTYLCYCLOHEXANOL, Tox21_201515, Tox21_303090, BBL019113, MFCD00064952, MFCD00070476, NSC404197, STL199047, TRANS-P-TERT-BUTYLCYCLOHEXANOL, AKOS000120382, AKOS015837822, AKOS015837824, CS-W010920, NSC-404197, SB83913, SB84138, NCGC00164215-01, NCGC00164215-02, NCGC00256931-01, NCGC00259065-01, AS-60214, AS-60986, TRANS-1-TERT-BUTYLCYCLOHEXAN-4-OL, TRANS-4-TERT-BUTYL-1-CYCLOHEXANOL, WLN: L6TJ AX1 & 1 & 1 DQ, Cyclohexanol,4-(1,1-dimethylethyl)-,cis-, DB-045718, DB-080541, DB-369944, TRANS-4-TERT-BUTYLCYCLOHEXYL ALCOHOL, B0383, B1270, B1271, CS-0343022, CS-0343024, CYCLOHEXANOL, 4-TERT-BUTYL-, TRANS-, NS00002002, NS00079520, cyclohexanol, 4-(1,1-dimethylethyl)-, trans, EN300-20213, (1R,4R)-4-TERT-BUTYLCYCLOHEXAN-1-OL, EC 700-127-8, P20543, T70576, T71478, EN300-6735394, TRANS-4-TERT-BUTYLCYCLOHEXANOL [WHO-DD], A815716, A844682, A845870, A858538, A859665, Q-200399, Q27277664, Q27282714, F0001-2316, trans-4-(tert-Butyl)cyclohexanol relative stereochemistry, Z104477300

4-tert-Butylcyclohexanol is a clear synthetic liquid solution used for fast skin relief. 
It significantly alleviates stinging and burning by reducing stinging up to 78% after 3 minutes and burning up to 80% after 3 minutes. 
It is proven to soothen scalp sensitivities of burning and stinging during chemical color treatments.

4-tert-Butylcyclohexanol acts as a sensi-regulator and soothing active. 
A next generation neuro-sensorial active for sensitive skin with fast skin relief. 
4-tert-Butylcyclohexanol works at the cell communication level directly connecting with specific neuro-receptor TRPV1 thermo-receptor. 

Reduces the calcium flux in the cellular membrane bringing back to a normal state. 
4-tert-Butylcyclohexanol helps to increase the skin's tolerance threshold by its regulating action. 
It reduces sensitive symptoms & significantly burning and stinging. 

4-tert-Butylcyclohexanol is used in skin care and oral care application. 
4-tert-Butylcyclohexanol is a clear liquid solution of trans-4-tert-Butyl-1-cyclohexanol in Pentylene Glycol.
4-tert-Butylcyclohexanol is the new generation of actives for sensitive skin.

It is a TRPV1 receptor antagonist, acts as an anti-nerve hyperactivation and has an immediate effect on burning and stinging.
4-tert-Butylcyclohexanol has received the BSB Innovation Award 2010 as 'Most Innovative Raw Material Naturals/Actives'. 
As a specialist of skin discomfort and fragility for over 40 years, 4-tert-Butylcyclohexanol has been among the firsts to acknowledge sensitivity as a specific state of the skin. 

This has been the starting point of a dedicated research & development program. 
Scientific findings are constantly cross-referenced with market data on how sensitivity is being defined across the globe, in order to create solutions delivering optimal consumer experience.
One of the latest innovation was the development of an objective analytical tool based on AI to grade skin sensitivity with high correlation between self-perception and Hyperspectral image analysis this is how we define the Skin sensitivity index.

The Symrise portfolio of soothing actives was originally based on the established expertise in the design of pure molecules – including the purest synthetic bisabolol or advanced solutions in the field of Oat Avenanthramides.
In now extends to a wide range of natural and biotechnology ingredients offering targeted answers, such as restoring the skin’s barrier function, correcting redness, modulating neurosensory cascading reactions as well as novel Biotic solutions featured in the 4-tert-Butylcyclohexanol.

Acts as a humectant, helping to retain moisture in the skin.
4-tert-Butylcyclohexanol improves the texture and feel of the skin.
4-tert-Butylcyclohexanol enhances the effectiveness of preservatives in formulations by providing antimicrobial properties.

4-tert-Butylcyclohexanol soothes and reduces irritation for sensitive skin types.
Helps to hydrate and condition the skin, potentially reducing the appearance of fine lines and wrinkles.
Provides moisture and improves skin texture.

4-tert-Butylcyclohexanol maintains skin hydration while cleansing.
4-tert-Butylcyclohexanol enhances hydration and skin softness.
Reduces skin sensitivity and irritation.

Provides effective moisturizing properties.
4-tert-Butylcyclohexanol helps improve the stability of cosmetic formulations.
Generally well-tolerated, but patch testing is recommended for sensitive skin to avoid potential irritation.

Complies with cosmetic regulations in various regions; however, always verify local regulations.
Consider sustainable practices for sourcing and disposal to minimize environmental impact.

Melting point: 80 °C
Boiling point: 230.54°C (estimate)
Density: 0.9052 (estimate)
vapor pressure: 0.74-29Pa at 20-50℃
refractive index: 1.4583 (estimate)
FEMA: 4724 | TRANS-4-TERT-BUTYLCYCLOHEXANOL
pka: 15.32±0.40(Predicted)
form: Solid:flakes
Odor: at 10.00 % in dipropylene glycol. woody patchouli
Odor Type: woody
LogP: 3.42 at 25℃

4-tert-Butylcyclohexanol helps to reduce the perception of skin irritation and discomfort. 
It works by modulating the activity of sensory nerve endings in the skin, which can alleviate feelings of sensitivity.
Ideal for products designed for sensitive or reactive skin, helping to minimize redness and discomfort.

As a humectant, 4-tert-Butylcyclohexanol attracts moisture from the environment into the skin and helps retain it, maintaining skin hydration levels.
4-tert-Butylcyclohexanol supports skin barrier function and keeps the skin soft and supple.
Enhances the effectiveness of preservatives used in formulations by providing additional antimicrobial properties.

Improves the overall preservation of the product, reducing the need for higher concentrations of preservatives.
4-tert-Butylcyclohexanol is compatible with a wide range of cosmetic ingredients and can be easily incorporated into various formulations.
Helps improve the stability and texture of cosmetic products, contributing to their overall performance.

By maintaining skin hydration and improving skin texture, 4-tert-Butylcyclohexanol can contribute to a more youthful appearance.
Helps reduce the appearance of fine lines and wrinkles by keeping the skin moisturized and plump.
Provides deep hydration and enhances the soothing effects of serums.

4-tert-Butylcyclohexanol improves hydration and reduces skin sensitivity.
Maintains skin moisture during cleansing, preventing dryness.
Soothes and hydrates the delicate skin around the eyes.

Helps keep the skin hydrated while providing sun protection.
Generally considered safe for use in cosmetic formulations. 
4-tert-Butylcyclohexanol is important to use it within recommended concentrations to avoid any potential irritation.

Should be used with caution around the eyes. 
If contact occurs, rinse thoroughly with water.
4-tert-Butylcyclohexanol is biodegradable, but it is always good to consider the environmental impact of all ingredients and aim for sustainable practices.

Approved for use in cosmetics and personal care products by various regulatory bodies, including the FDA, EU, and others. 
Always check specific regulations in your region to ensure compliance.

Typically used in concentrations ranging from 1% to 5% in cosmetic formulations, depending on the desired effect.
Ensure proper formulation to maintain the stability and efficacy of 4-tert-Butylcyclohexanol in products.

Uses Of 4-tert-Butylcyclohexanol:
4-tert-Butylcyclohexanol is used as a reaction reagent and an intermediate in organic synthesis, mainly in chemical manufacturing or experimental research.
4-tert-Butylcyclohexanol designed to soothe and reduce irritation for sensitive skin types.
Helps to calm redness and discomfort, making it ideal for products labeled for sensitive or reactive skin.

Hydrates and conditions the skin by attracting moisture.
4-tert-Butylcyclohexanol enhances skin softness and suppleness, improving overall skin hydration.
Maintains skin hydration and improves texture.

Reduces the appearance of fine lines and wrinkles, contributing to a youthful appearance.
Provides deep hydration and soothing effects.
Helps to retain moisture and improve skin texture, enhancing the efficacy of the serum.

Maintains skin hydration while cleansing.
Prevents dryness and irritation that can be caused by the cleansing process.
Soothes and hydrates the delicate skin around the eyes.

Reduces puffiness and dryness in the sensitive eye area.
Hydrates the skin while providing sun protection.
Helps keep the skin moisturized and comfortable while exposed to the sun.

4-tert-Butylcyclohexanol enhances the moisturizing properties of lotions and creams.
Improves skin softness and hydration across the body.
Sometimes used in hair care formulations to condition and hydrate the scalp.

Helps maintain scalp moisture and improves the overall health of the hair.
Enhances the effectiveness of preservatives.
Provides additional antimicrobial properties, improving the stability and shelf life of products.

4-tert-Butylcyclohexanol reduces skin irritation and sensitivity.
Hydration: Keeps skin well-hydrated, improving overall skin health.
Enhances the stability of formulations by providing antimicrobial support.

4-tert-Butylcyclohexanol typically used at concentrations of 1% to 5%, depending on the product and desired effect.
Works well with a wide range of other cosmetic ingredients.
Enhances the moisturizing and soothing properties of acne treatment products.

Reduces dryness and irritation often associated with acne treatments, making them more comfortable to use.
4-tert-Butylcyclohexanol is used in formulations aimed at treating skin conditions such as eczema or psoriasis.
Provides moisture and helps to soothe irritated skin, supporting the skin's healing process.

4-tert-Butylcyclohexanol is used in face masks to provide deep hydration.
Improves the skin's moisture balance, leaving it feeling soft and rejuvenated.
Incorporated into after-sun care products.

Soothes and rehydrates sun-exposed skin, helping to alleviate discomfort.
4-tert-Butylcyclohexanol included in formulations for baby lotions, creams, and wipes.
Provides gentle hydration and reduces the risk of skin irritation.

4-tert-Butylcyclohexanol is used in aftershaves, shaving creams, and moisturizers.
Soothes the skin post-shaving and provides hydration.
4-tert-Butylcyclohexanol hydrating or anti-aging serums.

4-tert-Butylcyclohexanol products specifically designed for the under-eye area.
4-tert-Butylcyclohexanol facial and body cleansers.
Provides mild conditioning to the scalp.

4-tert-Butylcyclohexanol incorporates into topical acne solutions.
4-tert-Butylcyclohexanol found in after-sun lotions and gels.
4-tert-Butylcyclohexanol included in sunscreens and sunblock formulations.

4-tert-Butylcyclohexanol is used in products formulated for sensitive baby skin.
Improves the texture and feel of cosmetic formulations, leading to a smoother application.

Helps in extending the shelf life of products by enhancing the efficacy of preservatives.
Increases the overall comfort of products, making them suitable for sensitive and reactive skin types.

Safety Profile Of 4-tert-Butylcyclohexanol:
While 4-tert-Butylcyclohexanol is usually well-tolerated, high concentrations or prolonged exposure may cause skin irritation in some individuals.
Conduct patch testing before use in high concentrations or sensitive formulations.
Direct contact with the eyes can cause irritation or discomfort.

Avoid contact with eyes and rinse thoroughly with water if contact occurs.
Although rare, some individuals may develop allergic reactions or sensitivity to 4-tert-Butylcyclohexanol.
Perform a patch test before using products containing 4-tert-Butylcyclohexanol, especially for individuals with sensitive skin or known allergies.

Inhalation of high concentrations of 4-tert-Butylcyclohexanol in aerosolized or powdered form could potentially cause respiratory irritation.
Ensure proper ventilation when handling in bulk or concentrated forms.

While 4-tert-Butylcyclohexanol is biodegradable, excessive release into the environment could have localized effects on aquatic life.
Follow guidelines for responsible disposal and consider environmental regulations.