ADDOCAT 102

Addocat 102 is an aromatic heterocyclic organic compound with the formula CH3C3H3N2. 
Addocat 102 is a colorless to yellow liquid, with an amine-like odor. 
Addocat 102 is miscible with water. 

CAS Number: 616-47-7
Molecular Formula: C4H6N2
Molecular Weight: 82.1
EINECS Number: 210-484-7

Synonyms: 1-methylimidazole, 1-Methyl-1H-imidazole, 616-47-7, 1H-Imidazole, 1-methyl-, IMIDAZOLE, 1-METHYL-, N1-Methylimidazole, Araldite DY 070, EINECS 210-484-7, UNII-P4617QS63Y, NSC 88064, DTXSID6052291, CHEBI:113454, P4617QS63Y, NSC-88064, 1-methyl-1H-imidazol-3-ium, DTXCID6030863, EC 210-484-7, THIAMAZOLE IMPURITY B [EP IMPURITY], THIAMAZOLE IMPURITY B (EP IMPURITY), 1-methylimidazolium ethanoate, NMethylimidazole, Imidazole, 1methyl, 1HImidazole, 1methyl, 210-484-7, inchi=1/c4h6n2/c1-6-3-2-5-4-6/h2-4h,1h, mctwtzjpvlrjou-uhfffaoysa-n, un2922, N-Methylimidazole, N-methylimidazol, 1-methylimidazol, n-methyl imidazole, MFCD00005292, 1-methyl-imidazole, 1-methylimdazole, 1-Methyl-1H-imidazole; Thiamazole Imp. B (EP); Thiamazole Impurity B, 3-methylimidazole, N-methyl-imidazol, N-methyl-imidazole, 1-methyl imidazole, 1-N-methylImidazole, Lopac-M-8878, 1-methyl-(1H)-imidazole, CHEMBL543, 1-Methyl-1H-imidazole #, WLN: T5N CNJ A1, Lopac0_000831, 3-methyl-1H-imidazol-3-ium, BDBM7884, HMS3262H03, BCP29437, NSC88064, STR00990, Tox21_304006, Tox21_500831, BBL011447, STL146559, AKOS000119840, CCG-204915, CS-W008580, FM00853, LP00831, PS-9372, SDCCGSBI-0050808.P002, NCGC00015702-01, NCGC00015702-02, NCGC00015702-03, NCGC00015702-04, NCGC00094162-01, NCGC00094162-02, NCGC00261516-01, NCGC00357222-01, 1-Methylimidazole, ReagentPlus(R), 99%, 1-Methylimidazole, redistilled from glass, CAS-616-47-7, FM179985, PD015169, DB-002020, EU-0100831, M0508, NS00009025, EN300-21628, 1-Methylimidazole, puriss., >=99.0% (GC), D70869, M 8878, 1-Methylimidazole, Vetec(TM) reagent grade, 98%, SR-01000076013, Q4545792, SR-01000076013-1, 1-Methylimidazole, >=99%, purified by redistillation, F0001-1635, Z104506032, 1-Methyl-1H-imidazole;N-Methylimidazole;1H-Imidazole, 1-methyl-, Cap B (1-methylimidazole 16% in THF), for oligonucleotide synthesis, filtered through a 1mum filter, Capping B (10 % N-methylimidazole in THF / pyridine, V / V = 80 : 10) NC-0803 emp Biotech GmbH, Capping B, 16 % NMI in THF, emp Biotech GmbH (THF/N-methylimidazole, V / V = 84 : 16) NC-0801, 450ml : 28-400 thread, 2.5L : GL45 thread, N-methylimidazole (1-methylimidazole);N-methyl midazole;N-methyl glyoxaline;CAP B (1-METHYLIMIDAZOLE 12% IN ACETONIT;1-Methylimidazole, >=99%, purified by redistillation;CAP B (1-METHYLIMIDAZOLE 10% IN THF)*;CAP B (1-METHYLIMIDAZOLE 10% IN;CAP B (1-METHYLIMIDAZOLE 16% IN THF)*

Addocat 102 is an important raw material for the synthesis of pharmaceutical intermediates, used in the preparation of losartan, nizofenone, 1-Methyl-1H-imidazole-5-carbonyl chloride hydrochloride and naphazoline hydrochloride, etc. 
Addocat 102 is also used as a specialty solvent, a base, and as a precursor to some ionic liquids.
Addocat 102 is a 1H-imidazole having a methyl substituent at the N-1 position. 

Addocat 102 is a metabolite of 1-methyl-2-thioimidazole (methimazole). 
Addocat 102 inhibits bone resorption.
Addocat 102 is a polyurethane catalyst based on a tertiary amine, specifically N-methylimidazole. 

Addocat 102 activates the gelling (cross linking) reaction in rigid polyurethane foams.  
Addocat 102 produces tough and elastic skin, thus improving the adhesion of the foam to facings.  
Typically used in the continuous production of sandwich panels, discontinuous hear/cold insulation if refrigerators and piping, and for on-site casting.

Addocat 102 is a specialized chemical catalyst used primarily in the production of polyurethane systems. 
It is part of the class of organotin catalysts, which are employed to accelerate the reaction between polyols and isocyanates in the synthesis of polyurethanes.
As a catalyst, Addocat 102 plays a crucial role in enhancing the efficiency and speed of chemical reactions, particularly in the production of flexible and rigid foams, elastomers, coatings, adhesives, and sealants.

In addition to its primary role in polyurethane manufacturing, Addocat 102 is valued for its ability to promote selectivity in the reaction process, leading to better control over the properties of the final product, such as its viscosity, hardness, and foam structure. 
This ensures that the produced polyurethane materials meet specific performance criteria such as durability, flexibility, and heat resistance.
Although it is effective in a variety of applications, the use of Addocat 102 requires careful handling due to its chemical reactivity. 

Addocat 102 is typically handled with appropriate safety precautions, including protective gear, and must be stored in controlled environments to prevent degradation or unsafe reactions.
Addocat 102 has been enhanced for catalysis. 1-Methylimidazole is a derivative of imidazole that is utilized in the manufacture of such classes of items as pharmaceuticals, pesticides, ion-exchange resins, dye intermediates, textile auxiliaries, photographic chemicals, and corrosion inhibitors. 
It is also used as a catalyst for manufacturing polyurethanes and a curing agent for epoxy resins.

Addocat 102 is a polyurethane catalyst based on a tertiary amine, specically N-methylimidazole.
Addocat 102 activates the gelling (cross linking) reaction in rigid polyurethane foams.
Addocat 102 produces tough and elastic skin, thus improving the adhesion of the foam to facings.

Typically Addocat 102 is used in the continuous production of sandwich panels, discontinuous hear/cold insulation if refrigerators and piping, and for on-site casting.
Addocat 102 is also beneficial in the production of coatings and elastomers, where its catalytic properties are used to achieve specific curing times and optimize the final product’s durability and finish. 
In automotive manufacturing, it is used to create coatings and adhesives that are resistant to harsh conditions, such as extreme temperatures, UV radiation, and abrasion. 

These properties make it ideal for use in the production of vehicle parts that require tough, long-lasting surfaces, such as bumpers, trims, and dashboard elements.
In the construction industry, Addocat 102 plays a significant role in the formulation of high-performance sealants and adhesives. 
These are used in applications ranging from window sealing to flooring installation, where strong bonding and resistance to environmental factors like moisture and temperature fluctuations are critical. 

Addocat 102 ensures the proper curing of these products, leading to reliable and high-quality outcomes that meet the stringent demands of modern construction.
Addocat 102 is a 1-methylimidazole.
Addocat 102 acts as a crosslinking catalyst.

Addocat 102 gives the rigid foam a tough and elastic skin, thus improving the adhesion of the foam to facings, particularly in sandwich panels.
Addocat 102 is used for the production of polyurethane foam and discontinuous heat/cold insulation of refrigerators and piping.

Addocat 102 is a 1-methylimidazole. Acts as a crosslinking catalyst. 
Gives the rigid foam a tough and elastic skin, thus improving the adhesion of the foam to facings, particularly in sandwich panels. 
Used for the production of polyurethane foam and discontinuous heat/cold insulation of refrigerators and piping.

Melting point: −60 °C(lit.),
Boiling point: 198 °C(lit.),
Density: 1.03 g/mL at 25 °C(lit.),
vapor pressure: 0.4 mm Hg ( 20 °C),
refractive index: n20/D 1.495(lit.),
Flash point: 198 °F,
storage temp.: Store below +30°C.,
solubility: Chloroform (Slightly), Methanol (Slightly),
form: Liquid,
pka: 6.95(at 25℃),
Specific Gravity: 1.031,
color: Clear colorless to yellow,
PH: 9.5-10.5 (50g/l, H2O, 20℃),
PH Range: 9.5 - 11.5 at 100 g/l at 20 °C,
biological source: synthetic,
explosive limit: 2.7-15.7%(V),
Water Solubility: Miscible with water.,
Sensitive: Hygroscopic,
BRN: 105197,
Stability: Stable, but moisture sensitive. Incompatible with acids, acid anhydrides, strong oxidizing agents, moisture, carbon dioxide, acid chlorides.,
InChIKey: MCTWTZJPVLRJOU-UHFFFAOYSA-N,
LogP: -0.19 at 25℃.

Addocat 102 is widely used in the manufacturing of polyurethane-based products, specifically in industries such as automotive, construction, and furniture, where polyurethane foams, coatings, and adhesives are essential. 
As a catalyst, it facilitates the formation of polyurethanes by increasing the reaction rate between polyols and isocyanates, which are the fundamental building blocks of polyurethane polymers. 
Addocat 102s role is crucial in ensuring that these reactions occur at optimal speeds, making it a valuable component in large-scale industrial processes.

Moreover, Addocat 102 is often utilized in formulations requiring precise control over the reaction's timing and efficiency. 
This helps manufacturers produce consistent and high-quality products. 
For instance, in the production of rigid polyurethane foams used for insulation, Addocat 102 ensures that the foam achieves the desired thermal resistance properties, mechanical strength, and stability. 

In flexible foams, Addocat 102 helps to achieve the required softness and cushioning characteristics, making it a key ingredient in the bedding and automotive sectors.
The chemical properties of Addocat 102 also make it versatile in different polyurethane formulations, where it can be used to tailor specific properties like hardness, flexibility, or resistance to wear. 
In addition, it aids in the production of coatings and adhesives that are used in various applications, including paints, sealants, and automotive parts, where quick curing times and strong bonding capabilities are essential.

However, like many organotin compounds, Addocat 102 must be handled with care due to its potential toxicity. 
Addocat 102 can pose health risks if inhaled, ingested, or absorbed through the skin. 
Appropriate safety protocols, including the use of personal protective equipment (PPE), proper ventilation, and storage in non-reactive containers, are necessary to minimize exposure during its use. 

Addocat 102s environmental impact is also a concern, so disposal must be managed according to local regulations to avoid contamination.
Additionally, Addocat 102 can be employed in the creation of thermoplastic polyurethane (TPU), a material known for its excellent elasticity, transparency, and abrasion resistance. 
TPUs are used in a wide range of applications, including footwear, medical devices, and electronics. 

By enabling precise control over the polymerization process, Addocat 102 helps to tailor the TPU’s properties to suit different needs, such as flexibility, hardness, and resistance to oils and solvents.
Its application in the footwear industry is also notable, where it is used to manufacture soles that require high durability, comfort, and performance. 
Addocat 102 enables manufacturers to create consistent, high-quality TPU components for shoes, offering products that are lightweight, durable, and resistant to wear.

Despite its widespread use and effectiveness in industrial processes, caution must be exercised when handling Addocat 102 due to its potential toxicological effects. 
Prolonged exposure or misuse can lead to health problems, including skin irritation, respiratory issues, and possible reproductive toxicity. 
Therefore, the use of Addocat 102 is strictly regulated, and safety measures, such as the use of gloves, face protection, and effective ventilation systems, are required in industrial environments. 

Addocat 102’s environmental impact is also an important consideration, as it can contribute to pollution if not properly managed or disposed of. 
Manufacturers are encouraged to follow best practices and comply with environmental regulations to mitigate any negative effects.

Preparation: 
1-Methylimidazole is prepared mainly by two routes industrially. 
The main one is acid-catalysed methylation of imidazole by methanol. 
The second method involves the Radziszewski reaction from glyoxal, formaldehyde, and a mixture of ammonia and methylamine: (CHO)2 + CH2O + CH3NH2 + NH3 → H2C2N(NCH3)CH + 3 H2O

The compound can be synthesized on a laboratory scale by methylation of imidazole at the pyridine-like nitrogen and subsequent deprotonation. 
Similarly, 1-methylimidazole may be synthesized by first deprotonating imidazole to form a sodium salt followed by methylation.
H2C2N(NH)CH + CH3I → [H2C2(NH)(NCH3)CH]I
[H2C2(NH)(NCH3)CH]I + NaOH → H2C2N(NCH3)CH + H2O + NaI

Uses:
Addocat 102 is an aprotic solvent. 
Addocat 102 is a derivative of imidazole used in the production of pharmaceuticals, pesticides, ion exchange resins, dye intermediates, textile auxiliaries, photographic chemicals, and corrosion inhibitors. 
It can also be used as a catalyst for the manufacture of polyurethane and a curing agent for epoxy resins. 

For example, when 1-methylimidazole is added to an aqueous diethylenetriamine (DETA) solution, high CO2 loading can be achieved through phase separation of the absorbent during CO2 absorption.
Addocat 102 is primarily used as a catalyst in the polymerization of various chemical compounds, enabling efficient production of a wide range of industrial materials. 
Its most notable application is in the manufacturing of polyurethane products, where it plays a key role in the production of thermoset and thermoplastic polyurethanes (TPUs). 

TPUs are used extensively in industries such as automotive, construction, footwear, and medical devices, due to their excellent elasticity, transparency, and resistance to abrasion, oils, and solvents. 
Addocat 102 allows manufacturers to control the polymerization process, ensuring that the resulting products possess the desired properties, such as flexibility, hardness, and durability.
In the automotive industry, Addocat 102 is used in the production of coatings, adhesives, and sealants that are essential for creating durable and weather-resistant vehicle parts. 

For instance, it helps create coatings for car bumpers, trims, and dashboards, which require high resistance to UV radiation, extreme temperatures, and physical wear. 
The catalytic effect of Addocat 102 ensures that these materials cure properly, providing long-lasting, high-performance finishes that meet the stringent requirements of automotive applications.
Addocat 102 also plays a critical role in the construction sector, where it is used to facilitate the curing of sealants and adhesives that are applied in a variety of building projects. 

These include window sealing, flooring installation, and other applications that require strong bonding and resistance to environmental factors such as moisture, temperature fluctuations, and mechanical stress. 
The catalyst helps to ensure that these adhesives and sealants perform reliably over time, providing long-lasting solutions that withstand challenging conditions.
Moreover, Addocat 102 is used in the production of elastomers, where its catalytic properties enable the creation of materials that are both flexible and durable. 

These elastomers are employed in applications that require resistance to wear and tear, such as in the manufacturing of gaskets, O-rings, and other sealing components used in machinery and industrial equipment. 
By facilitating a controlled curing process, Addocat 102 ensures that these materials maintain their performance characteristics over time, contributing to the overall longevity and efficiency of the equipment in which they are used.

In the footwear industry, Addocat 102 is utilized in the production of shoe soles made from thermoplastic polyurethane. 
These soles need to be lightweight, durable, and resistant to abrasion, oils, and solvents. 
Addocat 102 helps manufacturers achieve the right balance of flexibility and durability, ensuring that the soles meet the demanding requirements for comfort and performance in everyday footwear. 

The catalyst ensures a consistent, high-quality finish that results in shoes that are both functional and long-lasting.
In addition to these industries, Addocat 102 is used in various other applications, including the production of adhesives for electronics, medical devices, and other high-performance materials. 
The compound’s versatility and efficiency in facilitating polymerization make it a crucial component in the formulation of a wide range of products that require precise control over material properties and curing times.

Safety Profile:
Inhalation, ingestion, or skin contact with Addocat 102 may pose health risks. 
Prolonged or repeated exposure to the substance could irritate the respiratory system, eyes, and skin. 
Addocat 102 can lead to symptoms such as coughing, shortness of breath, or irritation in the throat. 

In more severe cases, inhalation of vapors or dust may cause respiratory distress, especially in poorly ventilated areas. 
Contact with the skin or eyes can cause irritation, resulting in redness, itching, or burning sensations.
Addocat 102 may be toxic if ingested or absorbed through the skin. 

Addocat 102 is important to avoid accidental consumption or prolonged exposure, as exposure to certain concentrations can lead to more serious health effects. 
Chronic exposure to this chemical may cause cumulative toxic effects, although specific long-term toxicity data for Addocat 102 may be limited.
Addocat 102 is potentially flammable, and as such, it presents a fire hazard under certain conditions. 

The substance should be kept away from open flames, sparks, and heat sources. 
In case of a fire, it could release harmful combustion products, including smoke and gases that may be toxic or hazardous to health.
The chemical may pose environmental risks if improperly disposed of. 

If spilled or released into the environment, particularly water bodies, it could have adverse effects on aquatic life, leading to contamination. Proper containment and disposal procedures should be followed to minimize environmental impact. 
Addocat 102 is crucial to prevent the chemical from entering sewage systems, rivers, or other natural habitats.
Addocat 102 may react with certain chemicals, such as strong oxidizing agents, acids, or moisture, leading to potentially hazardous conditions. 

Such reactions can result in the release of toxic or flammable gases and create additional safety concerns. 
Users should be cautious when mixing or handling Addocat 102 with other chemicals, and ensure that it is stored in compatible conditions to prevent unwanted reactions.
Proper handling and storage are essential to minimize hazards associated with Addocat 102. 

Addocat 102 should be stored in tightly sealed containers, in cool, dry, and well-ventilated areas away from incompatible substances. 
Protective equipment, such as gloves, safety glasses, and respirators, should be worn when handling the chemical to minimize exposure.