ALKYL (C12-C14) DIMETHYL(ETHYLBENZYL)AMMONIUM CHLORIDE

ALKYL (C12-C14) DIMETHYL(ETHYLBENZYL)AMMONIUM CHLORIDE = N-ALKYL ETHYLBENZYL DIMETHYL AMMONIUM CHLORIDE (C12-C14)

CAS Number: 85409-23-0
EC Number: 287-090-7
Molecular Formula : C11(CH2)nH17ClN

Alkyl (C12-C14) dimethyl(ethylbenzyl)ammonium chloride is a quaternary ammonium compound with surfactant properties. 
Alkyl (C12-C14) dimethyl(ethylbenzyl)ammonium chloride is found in sanitizing solutions or soaps as an active ingredient due to its antimicrobial properties.
Employed in a great variety of cleaning agents and sanitizing agents, Alkyl (C12-C14) dimethyl(ethylbenzyl)ammonium chloride possesses relatively broad gram-positive and gram-negative antibacterial activities and relatively little chance for systemic absorption and exposure, although the formal mechanism of action of quaternary ammonium compounds like Alkyl (C12-C14) dimethyl(ethylbenzyl)ammonium chloride is difficult to elucidate.
Alkyl (C12-C14) dimethyl(ethylbenzyl)ammonium chloride is registered under the REACH Regulation and is manufactured in and / or imported to the European Economic Area, at ≥ 10 to < 100 per annum.

Mechanism of action of Alkyl (C12-C14) dimethyl(ethylbenzyl)ammonium chloride:
Quaternary ammonium compounds like Alkyl (C12-C14) dimethyl(ethylbenzyl)ammonium chloride irreversibly bind to the phospholipids and proteins of microbial cell membranes, thereby impairing membrane permeability. 
Consequently, the antibacterial actions of Alkyl (C12-C14) dimethyl(ethylbenzyl)ammonium chloride generally stem from the capacity of bacterial cells to absorb the compound, causing the disruption or dissociation of cellular membrane lipid bilayers of bacteria, resulting in compromised cellular permeability control and the leakage of important cellular contents. 

In particular, the antimicrobial activity of quaternary ammonium with an alkyl chain is related to lipolhilia and peaks between C12 and C16 for both gram-positive and gram-negative bacterial strains. 
Specifically, in gram-positive bacteria, the agent becomes bound to the wall proteins and is, therefore, able to enter and destroy the membrane. 
Additionally, in some microbes, Alkyl (C12-C14) dimethyl(ethylbenzyl)ammonium chloride can cause a leak in metabolites with low molecular weights, resulting in metabolic injury and modification of permeability for the microbe.

It is for these aforementioned mechanisms of action that Alkyl (C12-C14) dimethyl(ethylbenzyl)ammonium chloride is capable of eliciting antimicrobial activity when used as a disinfectant. 
However, when used as an agent for routine cleaning where surface contamination with pathogenic bacteria and viruses does not necessarily present a hazard, the use of Alkyl (C12-C14) dimethyl(ethylbenzyl)ammonium chloride and its antimicrobial actions may not be entirely necessary or recommended, considering quaternary ammonium compounds like Alkyl (C12-C14) dimethyl(ethylbenzyl)ammonium chloride can persist on cleaned surfaces and contribute to prolonged topical exposure to individuals.

Quaternary ammonium compounds are poorly absorbed by the oral route of administration. 
At the same time, systemic effects from percutaneous absorption through intact skin is considered rare as well. 
Nevertheless, although potentially minimal, systemic absorption is possible.
As quaternary ammonium compounds like Alkyl (C12-C14) dimethyl(ethylbenzyl)ammonium chloride is poorly absorbed by the oral route, relatively large amounts of the agent that is absorbed is likely to be eliminated in the faeces.

USES and APPLICATIONS of ALKYL (C12-C14) DIMETHYL(ETHYLBENZYL)AMMONIUM CHLORIDE: 
-Alkyl (C12-C14) dimethyl(ethylbenzyl)ammonium chloride is added to products to function as a cleaning agent, or as antimicrobial agents in disinfecting cleaning products.
-Pharmacodynamics:
Alkyl (C12-C14) dimethyl(ethylbenzyl)ammonium chloride is a quaternary ammonium compound that demonstrates antimicrobial activity 1,5,4,6,7. 
In particular, a high degree of microbiocidal activity in hard water is obtained with a blend of two quaternary ammonium chlorides or bromides where the quaternary ammonium cation of each quaternary component is alkyl dimethyl ethylbenzyl and wherein the the alkyl group in once case is C12 and in the other case is C14, with these compounds being present only within the range of 85/15 to 55/45 of the C12 compound relative to the C14 compound 6.
Quaternary ammonium compounds like Alkyl (C12-C14) dimethyl(ethylbenzyl)ammonium chloride have subsequently shown antimicrobial activity against both gram positive and negative bacteria as well as a certain extent of antifungal activity and certain actions against particular virus types.
-As a component of cleaning agents and disinfectants, topical exposure is largely the most common form of Alkyl (C12-C14) dimethyl(ethylbenzyl)ammonium chloride exposure to humans. 
Regardless, when Alkyl (C12-C14) dimethyl(ethylbenzyl)ammonium chloride is in contact with human skin, percutaneous absorption through intact skin is believed to be minimal, and so systemic effects from topical exposure is expected to be rare.
-Alkyl (C12-C14) dimethyl(ethylbenzyl)ammonium chloride is used by consumers, by professional workers (widespread uses), in formulation or re-packing and at industrial sites.
-Biocidal Uses of Alkyl (C12-C14) dimethyl(ethylbenzyl)ammonium chloride:
Alkyl (C12-C14) dimethyl(ethylbenzyl)ammonium chloride is being reviewed for use as a biocide in the EEA and/or Switzerland, for: human hygiene, disinfection, veterinary hygiene, food and animals feeds, preservation for construction materials, preservation for liquid systems, controlling slimes, embalming or taxidermy.
-Consumer Uses of Alkyl (C12-C14) dimethyl(ethylbenzyl)ammonium chloride:
Alkyl (C12-C14) dimethyl(ethylbenzyl)ammonium chloride is used in the following products: washing & cleaning products, plant protection products and polishes and waxes.
Other release to the environment of Alkyl (C12-C14) dimethyl(ethylbenzyl)ammonium chloride is likely to occur from: indoor use as processing aid and outdoor use as processing aid.

PHYSICAL and CHEMICAL PROPERTIES of ALKYL (C12-C14) DIMETHYL(ETHYLBENZYL)AMMONIUM CHLORIDE:
Appearance Form: Wax like
Color: colorless, beige
Odor: characteristic
Odor Threshold: No data available
pH: No data available
Melting point/freezing point: No data available
Initial boiling point and boiling range: No data available
Flash point: Not applicable
Evaporation rate: No data available

Flammability (solid, gas): No data available
Upper/lower flammability or explosive limits: No data available
Vapor pressure: < 0,00001 hPa at 25 °C
Vapor density: No data available
Relative density: ca.0,82 at 20 °C 
Water solubility: ca.0,294 g/l at 20 °C
Partition coefficient: n-octanol/water: No data available
Autoignition temperature: > 400 °C
Decomposition temperature: No data available

Viscosity 
Viscosity, kinematic: No data available
Viscosity, dynamic: No data available
Explosive properties: No data available
Oxidizing properties: No data available
Other safety information:
Surface tension. ca.30,1 mN/m at 20 °C- surface-active substances
Density: 0.82 [at 20℃]
Vapor pressure: 0 Pa at 25℃

solubility: 93.7g/L in organic solvents at 20 ℃
form: neat
Water Solubility: 312mg/L at 20℃
LogP: 2.48 at 20℃
Molar Mass: 368.039
Density: 0.82 [at 20℃]
Water Solubility: 312mg/L at 20℃
Solubility: 93.7g/L in organic solvents at 20 ℃
Vapor Presure: 0 Pa at 25℃
Appearance: neat

FIRST AID MEASURES of ALKYL (C12-C14) DIMETHYL(ETHYLBENZYL)AMMONIUM CHLORIDE:
-Description of first-aid measures:
*General advice:
First aiders need to protect themselves. 
Show this material safety data sheet to the doctor in attendance.
*If inhaled:
After inhalation: 
Fresh air. 
Call in physician.

*In case of skin contact: 
Take off immediately all contaminated clothing. 
Rinse skin with water/ shower. 
Call a physician immediately.
*In case of eye contact:
After eye contact: 
Rinse out with plenty of water. 
Remove contact lenses.
*If swallowed:
After swallowing:  
Do not attempt to neutralise.
-Indication of any immediate medical attention and special treatment needed:
No data available

ACCIDENTAL RELEASE MEASURES of ALKYL (C12-C14) DIMETHYL(ETHYLBENZYL)AMMONIUM CHLORIDE:
-Environmental precautions:
Do not let product enter drains.
-Methods and materials for containment and cleaning up:
Collect, bind, and pump off spills. 
Take up with suitable equipment. 
Dispose of properly. 

FIRE FIGHTING MEASURES of ALKYL (C12-C14) DIMETHYL(ETHYLBENZYL)AMMONIUM CHLORIDE:
-Extinguishing media:
*Suitable extinguishing media:
Water 
Foam 
Carbon dioxide (CO2) 
Dry powder
*Unsuitable extinguishing media:
For this substance/mixture no limitations of extinguishing agents are given.
-Further information.
Prevent fire extinguishing water from contaminating surface water or the ground water system.

EXPOSURE CONTROLS/PERSONAL PROTECTION of ALKYL (C12-C14) DIMETHYL(ETHYLBENZYL)AMMONIUM CHLORIDE:
-Control parameters:
--Ingredients with workplace control parameters:
-Exposure controls:
--Personal protective equipment:
*Eye/face protection:
Use equipment for eye protection.
Tightly fitting safety goggles
*Skin protection:
Full contact:
Material: Nitrile rubber
Minimum layer thickness: 0,11 mm
Break through time: 480 min
Splash contact:
Material: Nitrile rubber
Minimum layer thickness: 0,11 mm
Break through time: 480 min
*Body Protection:
protective clothing
-Control of environmental exposure:
Do not let product enter drains.

HANDLING and STORAGE of ALKYL (C12-C14) DIMETHYL(ETHYLBENZYL)AMMONIUM CHLORIDE:
-Precautions for safe handling:
*Advice on safe handling:
Handle under argon.
*Hygiene measures
Immediately change contaminated clothing. 
Apply preventive skin protection. 
Wash hands and face after working with substance.
-Conditions for safe storage, including any incompatibilities:
*Storage conditions:
Tightly closed. 
Dry.
*Storage stability:
Recommended storage temperature: 2 - 8 °C

STABILITY and REACTIVITY of ALKYL (C12-C14) DIMETHYL(ETHYLBENZYL)AMMONIUM CHLORIDE:
-Reactivity:
No data available
-Chemical stability:
The product is chemically stable under standard ambient conditions (room temperature) .
-Possibility of hazardous reactions:
No data available
-Conditions to avoid:
no information available

SYNONYMS:
N-alkyl ethylbenzyl dimethyl ammonium (C12-C14) cation
C12-14-Alkyldimethyl(ethylbenzyl) ammonium chlorides
Quaternary ammonium compounds, C12-14-alkyl((ethylphenyl)methyl)dimethyl, chlorides
C12-14-Alkyldimethyl(ethylbenzyl)ammonium chloride
C12-14-Alkyldimethyl(ethylbenzyl)ammonium chloride
C12-C14 ALKYLDIMETHYL(ETHYLBENZYL)AMMONIUMCHLORIDE
C12-14-Alkyldimethyl(ethylbenzyl)ammonium chloride
C12-C14-Alkyl(ethylbenzyl)dimethylammonium chloride
Alkyl(C12-C14) dimethylethylbenzyl ammonium chloride
C12-14-Alkyldimethyl(ethylbenzyl) ammonium chlorides
Alkyl dimethyl ethyl benzyl ammonium chloride 
n-Alkyl dimethyl ethylbenzyl ammonium chloride
UP40
organicsurfactant
C12-14 ethyl benzyl ammonium chloride
C12-C14ALKYLDIMETHYL(ETHYLBENZYL)AMMONIUMCHLORIDE
C12-14-Alkyldimethyl(ethylbenzyl)ammonium chloride
Alkyl dimethyl ethyl benzyl ammonium chloride 
C12-C14-Alkyl(ethylbenzyl)dimethylammonium chloride
C12-14-alkyl[(ethylphenyl)methyl]dimethyl, chloride
C12-14-Alkyldimethyl(ethylbenzyl) ammonium chlorides
Quaternary ammonium compounds
C12-14-alkyl[(ethylphenyl)methyl]dimethyl, chloride
n-Alkyl Dimethyl Ethylbenzyl ammonium chloride
Alkyl(C12-C14) dimethylethylbenzyl ammonium chloride
C12-C14Alkyldimethyl(ethylbenzyl)ammoniumchloride
Alkyl(68%C12, 32%C14) dimethyl ethyl benzyl ammonium chloride
N-(4-ethylbenzyl)-N,N-dimethyldodecan-1-aminium chloride
Alkyl(68%C12,32%C14)dimethyl ethyl benzylammonium chloride
Alkyl(68%C12,32%C14) dimethyl ethyl benzyl ammonium chloride
UP40
C12-14-Alkyldimethyl(Ethylbenzyl)Ammonium Chloride
Quaternary ammonium compounds, C12-14-alkyl[(ethylphenyl)methyl]dimethyl, chlorides
C12-C14ALKYLDIMETHYL(ETHYLBENZYL)AMMONIUMCHLORIDE
C12-14-Alkyldimethyl(ethylbenzyl)ammonium chloride
C12-14-Alkyldimethyl(ethylbenzyl) ammonium chlorides
Alkyl(68%C12,32%C14)diMethyl ethyl benzylaMMoniuM chloride
Alkyl diMethyl ethyl benzyl aMMoniuM chloride