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Alpha-tocopherol is the most biologically active form of vitamin E, a powerful lipid-soluble antioxidant widely used in cosmetics, skincare, nutritional supplements, and pharmaceutical applications.
This compound is highly valued for its ability to protect skin and cellular membranes from oxidative damage caused by free radicals.
Alpha-tocopherol also supports skin barrier function, enhances moisture retention, and contributes to anti-aging and photoprotective formulations.
CAS Number: 59-02-9
EC Number: 200-412-2
Molecular Formula: C₂₉H₅₀O₂
Molecular Weight: 430.71 g/mol
Synonyms: Alpha-Tocopherol, d-Alpha Tocopherol, dl-Alpha-Tocopherol, Vitamin E, Natural Vitamin E, Synthetic Vitamin E, Tocopherol, RRR-Alpha-Tocopherol, D-alpha-tocopherol acetate, D-alpha tocopherol succinate, Vitamin E compound, Vitamin E oil, Alpha Tocopherol USP, Vitamin E pure, Tocopherol Vitamin E, Alpha Tocopherol antioxidant, E307, Mixed tocopherols, Alpha tocopherol (RRR), Alpha tocopherol concentrate, Vitamin E primary form, Tocopherol antioxidant agent, Natural tocopherol, Alpha tocopherol extract, Vitamin E supplement, Alpha tocopherol D-form, Alpha tocopherol lipophilic antioxidant, Alpha tocopherol cosmetic grade, Alpha tocopherol food grade, Alpha tocopherol topical grade, Tocopherol-rich vitamin E, Alpha tocopherol bioactive form, Alpha tocopherol EU additive
APPLICATIONS
Alpha-tocopherol is widely used in moisturizers, serums, and anti-aging creams for its antioxidant and skin-repairing benefits.
Alpha-tocopherol is included in sunscreen and after-sun care products to protect skin from UV-induced oxidative stress.
Alpha-tocopherol is employed in eye creams and facial oils to support skin regeneration and reduce the appearance of fine lines.
Alpha-tocopherol is applied in lip balms, glosses, and lip treatments for its nourishing and protective effects.
Alpha-tocopherol is used in body lotions, hand creams, and cuticle oils to improve skin softness and elasticity.
Alpha-tocopherol is included in hair conditioners, serums, and scalp treatments to enhance shine and strengthen hair fibers.
Alpha-tocopherol is added to bath and shower products for antioxidant and moisturizing support.
Alpha-tocopherol is utilized in baby care products for its mild and non-irritating protection.
Alpha-tocopherol is used in topical pharmaceutical preparations for wound healing and scar care.
Alpha-tocopherol is incorporated into dietary supplements for general health, immune support, and skin protection.
Alpha-tocopherol is used in fortified foods, beverages, and nutraceuticals as a functional nutrient.
Alpha-tocopherol is applied in animal nutrition formulations to enhance reproductive health and oxidative defense.
Alpha-tocopherol is included in cosmetic formulations as a natural preservative and formulation stabilizer.
Alpha-tocopherol is used in oil-based formulations to delay rancidity and extend shelf life.
Alpha-tocopherol is compatible with emulsifiers, botanical oils, esters, and other actives across diverse systems.
Alpha-Tocopherol, also known as Vitamin E, is widely used in the cosmetic industry as an antioxidant, where it helps protect the skin from oxidative stress caused by free radicals and environmental factors such as UV rays and pollution.
Alpha-Tocopherol is employed in the formulation of anti-aging skin care products, where it helps reduce the appearance of fine lines and wrinkles, promoting smoother and healthier skin.
Alpha-Tocopherol is used in moisturizing creams and lotions, where it helps to hydrate and protect the skin, improving its elasticity and preventing dryness.
Alpha-Tocopherol is used in sunscreens, where it provides additional antioxidant protection, reducing UV-induced damage to the skin and enhancing the overall sun protection factor (SPF) of the product.
Alpha-Tocopherol is applied in hair care products, such as shampoos and conditioners, where it helps nourish the scalp and hair, promoting healthy hair growth and reducing the appearance of split ends.
Alpha-Tocopherol is used in wound healing creams and ointments, where it accelerates the healing process by supporting tissue repair and reducing scarring.
Alpha-Tocopherol is employed in eye creams and serums, where it helps to protect the delicate skin around the eyes from oxidative damage and reduces puffiness and dark circles.
Alpha-Tocopherol is used in lip care products, such as lip balms and glosses, where it helps to moisturize and protect the lips from dryness and environmental damage.
Alpha-Tocopherol is applied in the formulation of scar treatments, where it helps improve the appearance of scars by promoting healing and reducing the formation of scar tissue.
Alpha-Tocopherol is used in anti-inflammatory skincare products, where it helps soothe irritated or inflamed skin and reduces redness caused by conditions like eczema and dermatitis.
Alpha-Tocopherol is used in the production of baby care products, where its gentle antioxidant properties help protect and nourish the sensitive skin of infants.
Alpha-Tocopherol is employed in the formulation of anti-pollution skincare products, where it helps protect the skin from damage caused by free radicals and environmental pollutants.
Alpha-Tocopherol is used in the production of anti-acne treatments, where it helps to reduce inflammation and prevent scarring, promoting clearer and healthier skin.
Alpha-Tocopherol is applied in the formulation of skin whitening products, where it helps reduce pigmentation and lighten dark spots caused by sun exposure or aging.
Alpha-Tocopherol is used in the production of hair growth products, where it helps to nourish the scalp and improve the overall health of the hair follicles.
Alpha-Tocopherol is used in the formulation of deodorants, where it helps reduce the appearance of discoloration and provides antioxidant protection to the underarm skin.
Alpha-Tocopherol is employed in the production of personal care products for sensitive skin, where it helps provide soothing effects and restore balance to irritated or reactive skin.
Alpha-Tocopherol is used in the formulation of therapeutic body oils, where it improves skin hydration, protects against free radical damage, and leaves the skin soft and smooth.
Alpha-Tocopherol is used in moisturizers for dry and cracked skin, where it helps improve skin texture and elasticity, providing long-lasting hydration and protection.
Alpha-Tocopherol is applied in facial serums and oils, where it helps to nourish the skin deeply, improve its appearance, and prevent the signs of premature aging.
Alpha-Tocopherol is used in the formulation of sunburn relief creams, where it helps to soothe and heal sunburned skin by promoting the regeneration of damaged tissues.
Alpha-Tocopherol is employed in the production of anti-wrinkle treatments, where it helps to promote skin regeneration, reduce the appearance of fine lines, and restore a youthful appearance.
Alpha-Tocopherol is used in the formulation of hand creams and foot creams, where it helps to prevent cracking and dryness, leaving the skin soft and nourished.
Alpha-Tocopherol is used in the formulation of body scrubs, where it helps improve skin texture, providing a smooth and rejuvenated appearance while protecting against environmental damage.
Alpha-Tocopherol is applied in the formulation of massage oils, where it helps to condition the skin, providing deep hydration and enhancing the benefits of the massage.
DESCRIPTION
Alpha-tocopherol is a viscous, amber to yellow oil with a mild odor and excellent lipid solubility.
It is a naturally occurring form of vitamin E and the most active isoform in humans, essential for cellular protection against lipid peroxidation.
Alpha-tocopherol stabilizes cell membranes and supports skin's natural defense against oxidative stress.
Alpha-tocopherol exhibits excellent skin penetration and is a potent scavenger of reactive oxygen species (ROS).
It improves skin hydration by reinforcing the skin barrier and reducing transepidermal water loss (TEWL).
Alpha-tocopherol contributes to improved skin elasticity, softness, and resilience in cosmetic products.
Alpha-tocopherol is stable in anhydrous and low-water formulations and can be protected with packaging and co-antioxidants.
It enhances the performance of other antioxidants such as Vitamin C and ferulic acid in synergistic formulations.
Alpha-tocopherol is safe, biodegradable, and compliant with cosmetic, food, and pharmaceutical regulations.
Alpha-Tocopherol, commonly known as Vitamin E, is a fat-soluble antioxidant that is naturally found in various foods and is widely used in cosmetic, pharmaceutical, and food applications for its protective properties against oxidative stress and environmental damage.
Alpha-Tocopherol is a potent antioxidant that works by neutralizing free radicals, which are highly reactive molecules that can damage cells and contribute to the aging process, making it a key ingredient in anti-aging products.
Alpha-Tocopherol is a clear to yellowish oily liquid, often used in its pure form or as part of a mixture of tocopherols (such as in Vitamin E oils) in cosmetic products for its ability to moisturize, protect, and rejuvenate the skin.
Alpha-Tocopherol is a powerful anti-inflammatory agent that helps reduce redness and irritation in the skin, making it suitable for sensitive or inflamed skin conditions such as eczema or rosacea.
Alpha-Tocopherol is often included in skin care formulations to enhance the skin's natural barrier, improving moisture retention and reducing the risk of dehydration and skin dryness.
Alpha-Tocopherol is stable under most conditions and is highly resistant to heat and light, which makes it an ideal ingredient in formulations that require long shelf-life stability.
Alpha-Tocopherol is also used in food products, where it acts as a preservative by preventing the oxidation of fats and oils, maintaining the freshness and quality of the product.
Alpha-Tocopherol is considered safe for use in a wide range of concentrations in cosmetic products, providing skin benefits without the risk of irritation or sensitization when used as directed.
Alpha-Tocopherol is commonly used in hair care formulations, where it provides nourishment to the hair and scalp, promoting healthy hair growth and reducing damage caused by free radicals.
Alpha-Tocopherol is an essential nutrient for humans, playing a vital role in maintaining overall health by supporting immune function, cardiovascular health, and the protection of cells from oxidative damage.
PROPERTIES
Chemical Formula: C₂₉H₅₀O₂
Molecular Weight: 430.71 g/mol
Common Name: Alpha-tocopherol / Vitamin E
Appearance: Amber to yellow viscous oil
Odor: Mild, characteristic
Solubility: Lipid-soluble; insoluble in water
Boiling Point: Approx. 200°C (decomposes)
Density: Approx. 0.95 g/cm³
Stability: Stable under anhydrous conditions and nitrogen protection
Oxidation Sensitivity: Sensitive to light and oxygen
Storage Temperature: Store between 10–25°C, away from light and air
Shelf Life: 24–36 months in sealed, nitrogen-protected packaging
FIRST AID
Inhalation:
Remove to fresh air if vapor is inhaled in large quantity.
Seek medical advice if symptoms occur.
Skin Contact:
Wash exposed skin with soap and water.
Generally non-irritating, but consult a doctor if reaction develops.
Eye Contact:
Rinse eyes with plenty of water for at least 15 minutes.
Seek medical assistance if irritation continues.
Ingestion:
Rinse mouth and drink water.
Seek medical advice if discomfort arises from high intake.
Note to Physicians:
Treat symptomatically.
Alpha-tocopherol is generally low toxicity.
HANDLING AND STORAGE
Handling:
Wear appropriate protective equipment during industrial handling.
Avoid prolonged exposure to light, air, and high temperature.
Work under inert gas conditions if possible.
Spill and Leak Procedures:
Absorb with inert material and clean the area with a suitable solvent.
Dispose in accordance with local regulations.
Storage:
Store Alpha-tocopherol in tightly sealed, opaque containers under nitrogen or inert gas.
Keep in a cool, dry, and dark place to prevent oxidation.
Avoid contamination with metal ions and strong oxidizers.
Handling Cautions:
Ensure hygienic handling and prevent moisture ingress.
Use clean, dry tools to avoid oxidative degradation.
