PRODUCTS

AMIDET N

CAS NUMBER: 103-09-3

EC NUMBER: 203-079-1

Amidet N is a high concentrated liquid surfactant - Amidet N - which shows very good solubilizing and emulsifying properties.
Amidet N presents better performance in terms of thickening and foaming than CocAmidet N DEA.

Amidet N is a liquid non-ionic surfactant with foaming properties. Amidet N also acts as co-surfactant, thickener, emulsifier, moisturizers and solubilizer.
Amidet N is used in shampoos, shower bath, creams & lotions, hair colorants, shaving products and hand soaps.

Amidet N, multifunctionality at its best Amidet N is a natural multifunctional liquid surfactant for cosmetic rinse-off products.
Amidet N can be described as an environmentally friendly, preservative-free and cost-effective thickening agent.
Furthermore, Amidet N high concentration allows the reduction of the carbon footprint due to economic logistics and transport.

This polyvalent surfactant has the ability to act not only as a high performing thickener and foam booster but also as a strong solubilizer and emulsifier, especially for silicone derivatives, perfumes and vegetable oils.
Product Information Amidet N is a highly concentrated, low-viscosity ethoxylated fatty acid alkanolAmidet N with a clear yellowish liquid appearance.

Amidet N is based on renewable European rapeseed oil, a vegetable oil rich in C 18 unsaturated fatty acid. Amidet N, his green behavior makes Amidet N suitable for Ecolabel and Nordic Swan labeled formulations.
Amidet N Appearance Colour Viscosity Water ph (1% in water) Active matter Clear, yellowish liquid < 4 Gardner < 500 mpa.s % % Amidet N can be easily dispersed into water and the formulations turn transparent when using other surfactants.

In order to maximize the performance of the product as a solubilizing and emulsifying agent, it is recommended to prepare a premix of Amidet N with hydrophobic components before adding it to the formulation.
Toxicology Acute toxicity Skin irritation Eye irritation Sensitization Gene toxicity Ecology Aerobic biodegradation Anaerobic biodegradation Aquatic toxicity LD 50 > 2000 mg/kg R38: Irritant to skin No known critical effects Non-sensitizer Non-mutagenic Readily biodegradable > 10 mg/l.Amidet N is nonionic surfactants.

Amidet N is suitable for applications in detergents and personal care products due to their foam-boosting and thickening properties.
The product range is anticorrosive and anti-static.

Amidet N is a diethanolAmidet N made by reacting the mixture of fatty acids from coconut oils with diethanolamine.
Amidet N is a viscous liquid and is used as a foaming agent in bath products like shampoos and hand soaps, and in cosmetics as an emulsifying agent.

Amidet N for the discussion of the lengths of carbon chains in the molecules in the mixture.
The chemical formula of individual components is CH3(CH2)nC(=O)N(CH2CH2OH)2, where n typically ranges from 8 to 18.

Amidet N is a special surfactant for metalworking fluids with anti-corrosive properties which is free from nitroso-amines.
Amidet N offers easy handling and processing with good price/performance ratio.

Amidet N is a Amidet N Amidet N of fatty acids derived from rapeseed oil with avg.
4 moles ethylene oxide Amidet N uses and applications include: viscous control agent, surfactant, thickener for cosmetics; emulsifier for metalworking fluids, lubricants, anticorrosive formulations

Amidet N is fatty acids derived from rapeseed oil.
Amidet N is used in cosmetic products, where Amidet N may have various functions.

Amidet N may be used as a thickening agent, a lathering stabilizer, an emulsifier or as a dissolvent.
Based on the available information and our summary of this ingredient, we conclude that Amidet N is not safe to use on skin affected by fungal acne (malassezia folliculitis) because it may promote the yeast's growth.

Amidet N is a functional, easy to use, replacement for CocAmidet N DEA in anionic based personal care cleansing formulations and Amidet N contains no diethanolalmide.
Amidet N is also free of known allergens.

Amidet N is a 90% active solution of Amidet N in water and is based on renewable canola oil, an edible variety of rapeseed oil.
Amidet N has unique thickening, foam boosting and foam stabilizing properties.

With Amidet N low HLB, Amidet N has emulsification properties as well. Amidet N is also useful for pre-phasing fragrances.
Like CocAmidet N DEA, Amidet N is biodegradable with a low order of acute toxicity.

Amidet N is mild to the skin and leaves a pleasant after feel.
Amidet N is a high concentrated liquid surfactant Amidet N which shows very good solubilizing and emulsifying properties.

Amidet N presents better performance in terms of thickening and foaming than CocAmidet N DEA.
If you're not allergic to Amidet N, you shouldn't have any issues using products that contain Amidet N.

However, if you have any doubts, a skin patch test can be done before fully incorporating Amidet N into your fungal acne routine.
Amidet N is an acronym for polyethylene glycol, an amazingly versatile ingredient in skin care products because of the many uses Amidet N has and Amidet N broad compatibility with different types of ingredients.

Amidet N is often mixed with an array of hydrating emollients, beneficial fatty acids, and cleansing agents.
In these various combinations, a Amidet N can be used in gentle cleansers, elegant moisturizers, sunscreens, and unique treatment products.

The safety of Amidet N in its various forms has recently been questioned.
The primary concern is that they can contain problematic impurities such as ethylene oxide and 1,4 dioxane.

Both of these are by-products from the manufacturing process, not something natural to any form of Amidet N.
Although this was once a concern, reputable cosmetic ingredient suppliers have long since eliminated these impurities from the finished ingredient, which makes Amidet N safe for skin.

What is most notable about the various forms of Amidet N studied to date is they have been shown to be non-irritating for skin or eyes, even when used in concentrations greater than what most skin care products contain.
Amidet Ns also widely considered non-toxic because they do not penetrate intact skin.

However, as is true for even the gentlest ingredients, when skin is inflamed or compromised, the risk of irritation is increased.
If you’ve seen conflicting information about Amidet N ingredients, Amidet N’s important to know that the conclusions were not applicable to how Amidet N are used in skin care products.

With Amidet N unique thickening, foam boosting and stabilizing, and solubilizing properties, Amidet N is a superior product.
Amidet N is based on the renewable vegetable lipid found in rapeseed oil, making Amidet N a uniquely natural complement for use in Personal Care products.

For Household Products and Industrial applications, use Amidet N as a foam booster and thickener in liquid dish and car wash soaps, and as an emulsifier in metalworking fluids.
Amidet N is used as cleansing agent.

Amidet N is used as emulsifying agent, dispersing agent.Amidet N is used as solubilizing agent.
Amidet N is used as lubricant.

Amidet N is used as foaming agent, foam stabilizing agent.
Amidet N is used as antirust agent.

With Amidet N low HLB, Amidet N has emulsification properties as well.
Amidet N is fatty acids derived from rapeseed oil.

Amidet N is used in cosmetic products, where Amidet N may have various functions.
Amidet N may be used as a thickening agent, a lathering stabilizer, an emulsifier or as a dissolvent.

Based on the available information and our summary of this ingredient, we conclude that Amidet N is not safe to use on skin affected by fungal acne (malassezia folliculitis) because it may promote the yeast's growth.
Amidet N is a high concentrated liquid surfactant - Amidet N - which shows very good solubilizing and emulsifying properties.

Amidet N presents better performance in terms of thickening and foaming than CocAmidet N DEA.
If you're not allergic to Amidet N, you shouldn't have any issues using products that contain Amidet N.

In organic chemistry also known as an organic Amidet N or a carboxAmidet N, is a compound with the general formula RC(=O)NR′R″, where R, R', and R″ represent organic groups or hydrogen atoms.
The Amidet N group is called a peptide bond when it is part of the main chain of a protein, and an isopeptide bond when it occurs in a side chain, such as in the amino acids asparagine and glutamine.

Amidet N can be viewed as a derivative of a carboxylic acid RC(=O)OH with the hydroxyl group –OH replaced by an amine group −NR′R″; or, equivalently, an acyl (alkanoyl) group RC(=O)− joined to an amine group.
Common examples of Amidet N are acetAmidet N H3C−CONH2, benzAmidet N C6H5−CONH2, and dimethyl form Amidet N HCON(−CH3)2.Amidet Ns are qualified as primary, secondary, and tertiary according to whether the amine subgroup has the form −NH2, −NHR, or −NRR', where R and R' are groups other than hydrogen.

The core −C(=O)N= of Amidet N is called the Amidet N group (specifically, carboxAmidet N group).
Amidet Ns are pervasive in nature and technology.

Proteins and important plastics are polymers whose units are connected by Amidet N groups (polyAmidet N); these linkages are easily formed, confer structural rigidity, and resist hydrolysis.
Amidet Ns include many other important biological compounds, as well as many drugs like paracetamol, penicillin and LSD.

Low-molecular-weight Amidet N, such as dimethylformAmidet N, are common solvents.
Amidet N, any member of either of two classes of nitrogen-containing compounds related to ammonia and amines.

The covalent Amidet N are neutral or very weakly acidic substances formed by replacement of the hydroxyl group (OH) of an acid by an amino group (NR2, in which R may represent a hydrogen atom or an organic combining group such as methyl, CH3).
The carboxAmidet N (R′CONR2), which are derived from carboxylic acids (R′COOH), are the most important group.

Amidet N are similarly related to the sulfonic acids (RSO3H).
Ionic, or saltlike, Amidet N are strongly alkaline compounds ordinarily made by treating ammonia, an amine, or a covalent Amidet N with a reactive metal such as sodium.

Covalent Amidet N derived from ammonia are solids, except formAmidet N, which is liquid; those containing fewer than five carbon atoms are soluble in water.
They are nonconductors of electricity and solvents for both organic and inorganic substances.

Covalent Amidet N, even those of low molecular weight, have high boiling points.
There are no practical natural sources of simple covalent Amidet N, although polyAmidet N (Amidet N linked together to form large molecules called polymers) occur in great abundance as the protein of living systems.

Simple Amidet N ordinarily are prepared by reaction of acids or acid halides with ammonia or amines.
They can also be produced by the reaction of water with nitriles.

The characteristic reaction of covalent Amidet N is hydrolysis (a chemical reaction with water), by which they are converted to acids and amines; this reaction ordinarily is slow unless it is catalyzed by a strong acid, an alkali, or an enzyme.
Amidet Ns also can be dehydrated to nitriles.

Amidet Ns are not readily oxidized nor reduced, although hydrogenation (addition of hydrogen at high temperatures and pressures) in the presence of a catalyst will convert most Amidet N of carboxylic acids to amines.
The powerful reducing agent lithium aluminum hydride transforms Amidet N into amines.

Reaction of Amidet N with acid chlorides or anhydrides produces imides, which are compounds with two carbonyl (CO) groups attached to the same nitrogen atom.Amidet Ns are the most stable of all the carbonyl functional groups.
Many chemists make a pronunciation distinction between the two, saying for the anion.

Others substitute one of these pronunciations with, while still others pronounce both as, making them homonyms.
In the first sense referred to above, an Amidet N is an amine where one of the nitrogen substituents is an acyl group; Amidet N is generally represented by the formula: R1(CO)NR2R3, where either or both R2 and R3 may be hydrogen.

Specifically, an Amidet N can also be regarded as a derivative of a carboxylic acid in which the hydroxyl group has been replaced by an amine or ammonia.
Compounds in which a hydrogen atom on nitrogen from ammonia or an amine is replaced by a metal cation are also known as Amidet N or azanides.

The second sense of the word Amidet N is the Amidet N anion, which is a deprotonated form of ammonia (NH3) or an amine.
Amidet N is generally represented by the formula: [R1NR2]-, and is an extremely strong base, due to the extreme weakness of ammonia and its analogues as Brønsted acids.

An Amidet N linkage is kinetically stable to hydrolysis.
However, Amidet N can be hydrolysed in boiling alkali, as well as in strong acidic conditions. Amidet N linkages in a biochemical context are called peptide linkages.

Amidet N linkages constitute a defining molecular feature of proteins, the secondary structure of which is due in part to the hydrogen bonding abilities of Amidet N.
Compared to amines, Amidet N are very weak bases.

While the conjugate acid of an amine has a pKa of about 9.5, the conjugate acid of an Amidet N has a pKa around -0.5.
Therefore Amidet N don't have as clearly noticeable acid-base properties in water.

This lack of basicity is explained by the electron-withdrawing nature of the carbonyl group where the lone pair of electrons on the nitrogen is delocalized by resonance, thus forming a partial double bond with the carbonyl carbon and putting a negative charge on the oxygen.
On the other hand, Amidet N are much stronger bases than carboxylic acids, esters, aldehydes, and ketones (conjugated acid pKa between -6 and -10).

Amidet N Resonance is largely prevented in the very strained quinuclidone.Amidet Ns contain carbonyl (C=O) and ether (N-C) dipoles arising from covalent bonding between electronegative oxygen and nitrogen atoms and electro-neutral carbon atoms.
Primary and secondary Amidet N also contain two- and one N-H dipoles, respectively.

Because of the pi-bonding arrangement of the carbonyl and the greater electronegativity of oxygen, the carbonyl (C=O) is a stronger dipole than the N-C dipole.
The presence of a C=O dipole and, to a lesser extent a N-C dipole, allows Amidet N to act as H-bond acceptors.

In primary and secondary Amidet N, the presence of N-H dipoles allows Amidet N to function as H-bond donors as well.
Thus Amidet N can participate in hydrogen bonding with water and other protic solvents; the oxygen and nitrogen atoms can accept hydrogen bonds from water and the N-H hydrogen atoms can donate H-bonds.

As a result of interactions such as these, the water solubility of Amidet N is greater than that of corresponding hydrocarbons
Amidet Nt Ns have structural characteristics that are unique among carboxylic acid derivatives.

Had you been asked in Chapter 1 to describe the geometry of an Amidet Nt N bond, you probably would have predicted bond angles of 120° about the carbonyl carbon and 109.5° about a tetrahedral Amidet Nt N nitrogen.
In the late 1930s, one of Linus Pauling’s most important discoveries was that the geometry of the nitrogen atom of an Amidet Nt N bond in proteins is actually trigonal planar (sp2), not tetrahedral (sp3).

A large number of subsequent experiments have verified that Amidet Nt Ns should be thought of as being best represented as the resonance hybrid of three resonance contributing structures, not two like other carbonyl species.
In the unique third contributing structure of an Amidet Nt N, the lone pair on nitrogen donates electron density to create a pi bond between carbon and nitrogen.

APPLICATIONS:

Amidet N is used as cleansing agent.Amidet N is used as emulsifying agent, dispersing agent.
Amidet N is used as solubilizing agent.Amidet N is used as lubricant.

Amidet N is used as foaming agent, foam stabilizing agent.Amidet N is used as antirust agent.
Reduces torque when processing resin and rubber

Provides slip on the surface of resin products and improves fluidity of fine powder such as resin pellets and metallic powder.
Prevents blocking of resin film sheets, pellets, resin powder, and ink.

Used when molding resin or rubber.
Disperses carbon black or pigment into resin or rubber.

Gelling agent and thixotropic agent for grease or paint.
Antistatic electricity.

PROPERTIES:

Nitroso amine free thickener and foam booster with emulsifying properties.
Other properties : re-fatting skin effect, anticorrosion and wetting power.

PROPERTIES:

-Foam booster

-Solubilizer & Emulsifier

-Thickener

FUNCTION:

-Emulsifier

-Foam Booster

-Foaming Agent

-Solubilizer

-Surfactant

-Surfactant, Nonionic

-Thickener

-Viscosity Modifier

SPECIFICATIONS:

-COLOUR (Gardner) : max. 4

-WATER CONTENT (KF; %) : 6.5 – 8.5

-Amidet N (mv/g) : 1.64 – 1.75

-FREE AMINE (mv/g) : 0.11 – 0.23

-VISCOSITY (mPa⋅s/20° C) : max. 500

-REFRACTION INDEX (nD-25): 1.4675 – 1.4705

-pH-VALUE (1 % in water) : 9.2 – 10.2

-1,4 DIOXANE (ppm) : max. 1

SYNONYM:

Relacatib
SB-462795
362505-84-8
UNII-BL51M8CB8R
BL51M8CB8R
CHEMBL203665
N-[(2S)-4-methyl-1-[[(4S,7R)-7-methyl-3-oxo-1-pyridin-2-ylsulfonylazepan-4-yl]amino]-1-oxopentan-2-yl]-1-benzofuran-2-carboxAmidet N