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AMONYL 380 BA is typically based on cocamidopropyl betaine–type chemistry or related betaine/zwitterionic surfactant systems.
AMONYL 380 BA is valued for its mildness, good foaming performance, and excellent compatibility with other surfactants.
AMONYL 380 BA contains both positively and negatively charged functional groups within the same molecule.
CAS Number: 61789-40-0
Molecular Formula: C19H38N2O3
Molecular Weight: 342.51662
EINECS Number: 263-058-8
Synonyms: NAXAINE C;NAXAINE CO;Lonzaine(R) C;Lonzaine(R) CO;Propanaminium, 3-amino-N-(carboxymethyl)-N,N-dimethyl-, N-coco acyl deriv;RALUFON 414;1-PropanaMiniuM, 3-aMino-N-(carboxyMethyl)-N,N-diMethyl;1-Propanaminium, 3-amino-N-(carboxymethyl)-N,N-dimethyl-, N-coco acyl derivs., hydroxides, inner salts
AMONYL 380 BA is an amphoteric surfactant.
The particular behaviour of amphoterics is related to their zwitterionic character; that means: both anionic and cationic structures are found in one molecule.
AMONYL 380 BA is a commercial amphoteric surfactant used mainly in personal care cleansing formulations such as shampoos, body washes, and facial cleansers.
This zwitterionic structure allows it to behave as cationic or anionic depending on formulation pH.
The molecule also contains a fatty alkyl chain derived from natural oils, providing surface activity and cleansing ability.
AMONYL 380 BA is supplied as a clear to slightly hazy liquid, usually colorless to pale yellow.
It is readily soluble in water and easily incorporated into cold-process formulations.
AMONYL 380 BA remains stable over a wide pH range typically used in cosmetic products.
In formulations, AMONYL 380 BA reduces surface tension and helps remove dirt, oil, and impurities from skin and hair.
It improves foam volume, foam creaminess, and foam stability.
It also reduces irritation potential of stronger anionic surfactants such as SLS or SLES when used in blends.
AMONYL 380 BA is widely used in shampoos, shower gels, body washes, facial cleansers, liquid hand soaps, and baby care products.
It enhances mildness, improves skin feel after rinsing, and reduces post-wash tightness.
AMONYL 380 BA also improves viscosity build-up and formulation stability in surfactant systems.
In hair care products, it improves softness and manageability while maintaining effective cleansing.
It helps reduce scalp irritation and supports gentle daily-use formulations.
AMONYL 380 BA is suitable for sulfate-free and sensitive-scalp products.
From a safety perspective, AMONYL 380 BA is generally considered low in toxicity and suitable for cosmetic use within regulatory limits.
Eye contact with concentrated material may cause moderate irritation.
Prolonged skin contact with undiluted product may cause mild irritation in sensitive individuals.
Inhalation risk is low because it is supplied as a liquid with low volatility.
However, aerosol formation during spraying or mixing may irritate the respiratory tract.
Adequate ventilation is recommended during industrial handling.
It is not classified as flammable and does not present explosion hazards under normal conditions.
Large environmental releases may increase organic load in water systems, although it is considered readily biodegradable.
Spills should be contained and disposed of according to local environmental regulations.
It should be stored in tightly closed containers, protected from freezing and excessive heat.
Long-term exposure to very high temperatures may affect viscosity and product stability.
It is compatible with anionic, amphoteric, non-ionic, and many cationic conditioning polymers such as Polyquaternium-7.
AMONYL 380 BA is an organic compound derived from coconut oil and dimethylaminopropylamine.
It is a zwitterion, consisting of both a quaternary ammonium cation and a carboxylate.
AMONYL 380 BA is available as viscous pale yellow solution that is used as a surfactant in personal care products.
AMONYL 380 BA is an amphoteric surfactant with an alkyl amido betaine structure.
AMONYL 380 BA acts as a foaming agent.
It is an amphoteric alkyl amido betaine.
AMONYL 380 BA is free of preservatives and sulfates.
AMONYL 380 BA stabilizes and boosts foam of anionic surfactants.
AMONYL 380 BA is used in shampoos, shower gels and foaming bath applications.
It is AMONYL 380 BA and China compliant.
AMONYL 380 BA is an amphoteric surfactant with an alkyl betaine structure.
Boiling point : 104.3 °C [at 101 325 Pa]
Density : 1.045–1.055 g/cm³
Vapor pressure : 0 Pa at 25 °C
Refractive index : 1.308–1.395
Storage temperature : Refrigerator
Solubility : Methanol (sparingly), Water (sparingly)
Form : Oil
Color : Colourless
Odor : Bland (at 100.00%)
Viscosity : 36.383 mm²/s
Water solubility : 23.676 g/L
Stability : Stable; combustible; incompatible with strong oxidizing agents
Cosmetics Ingredients Functions : SKIN CONDITIONING – MISCELLANEOUS; ANTISTATIC; SURFACTANT – CLEANSING; SURFACTANT – FOAM BOOSTING; HAIR CONDITIONING; VISCOSITY CONTROLLING; CLEANSING
InChI : InChI=1S/C19H38N2O3/c1-4-5-6-7-8-9-10-11-12-14-18(22)20-15-13-16-21(2,3)17-19(23)24/h4-17H2,1-3H3,(H-,20,22,23,24)
InChIKey : MRUAUOIMASANKQ-UHFFFAOYSA-N
SMILES : [O-]C(C([H])([H])N+
(C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])N([H])C(C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])=O)=O
LogP : −1.28
AMONYL 380 BA is perfectly compatible with anionic, cationic and nonionic surfactants, it can still be used as cloudy point inhibitor.
AMONYL 380 BA can produce rich and fine foams, fonnulated with adequate proportion of anionic surfactant, it has significant thickening effect.
AMONYL 380 BA has excellent to tolerance to skin, effectively reduce the irritation caused by fatty alcohol sulfate or fatty alcohol ether sulfate in the products.
AMONYL 380 BA has antibiotic function, being a good additive in personal sanitary products.
AMONYL 380 BA has excellent antistatic function, being an ideal conditioning agent.
Skin irritation: According to current OECD guideline, cocamidopropyl betaine (about 30% aqueous solution and nearly 80% spray-dried substance) is not a skin irritant.
In human studies up to 3 % solutions were weakly irritating.
Impurities like amidoamine may contribute to the irritation reaction.
The irritating properties of AMONYL 380 BA formulations could be significantly reduced by the addition of cocamidopropyl betaine.
AMONYL 380 BA is a commercial amphoteric (zwitterionic) surfactant used primarily in mild cleansing formulations for personal care applications.
It is designed to provide effective cleansing while minimizing irritation to skin and eyes.
AMONYL 380 BA is commonly selected for formulations intended for frequent use and sensitive skin.
AMONYL 380 BA is typically based on betaine-type chemistry, structurally similar to cocamidopropyl betaine or cocoamphoacetate derivatives.
The molecule contains both positively charged quaternary ammonium groups and negatively charged carboxylate groups.
It also contains a long-chain fatty alkyl group derived from coconut or palm-based fatty acids, which provides hydrophobic interaction with oils and dirt.
AMONYL 380 BA is supplied as an aqueous solution with moderate active matter content.
It appears as a clear to slightly opalescent liquid, colorless to pale yellow.
AMONYL 380 BA is fully soluble in water and easily disperses without heating, making it suitable for cold-process formulations.
AMONYL 380 BA remains stable over a broad pH range, typically from mildly acidic to neutral conditions.
AMONYL 380 BA is compatible with electrolytes and viscosity modifiers commonly used in shampoo and body wash systems.
It also shows good stability in the presence of hard water ions.
AMONYL 380 BA reduces surface tension and enables wetting and emulsification of oily soils.
It helps detach dirt, sebum, and cosmetic residues from skin and hair surfaces.
The contaminants are then dispersed into the wash water and removed during rinsing.
AMONYL 380 BA contributes to foam generation and improves foam creaminess and stability.
The foam produced is dense and fine-bubbled, which is associated with a pleasant sensory experience.
It also improves rinsability, leaving less residue on skin and hair.
AMONYL 380 BA acts as a secondary surfactant that boosts performance of primary anionic surfactants.
It reduces the harshness of systems containing SLES, SLS, or sulfonates.
This makes it especially useful in sulfate-containing and sulfate-free mild cleansing formulations.
AMONYL 380 BA is widely used in shampoos, shower gels, body washes, facial cleansers, liquid hand soaps, and intimate hygiene products.
It is also suitable for baby shampoos and sensitive-skin cleansers due to its low irritation profile.
AMONYL 380 BA improves after-wash skin feel and reduces tightness and dryness.
In hair care formulations, it supports gentle cleansing while maintaining scalp comfort.
AMONYL 380 BA helps reduce itching and irritation associated with frequent washing.
It improves hair softness and smoothness without heavy conditioning buildup.
In facial cleansing systems, it allows effective removal of makeup, sunscreen, and environmental pollutants.
AMONYL 380 BA maintains skin barrier comfort while preserving cleansing efficiency.
It is suitable for acne-prone and reactive skin formulations when properly balanced.
From a safety perspective, AMONYL 380 BA is considered low in acute toxicity and safe for cosmetic use within recommended concentrations.
Eye contact with the concentrated raw material may cause irritation and stinging.
Formulated products are usually much less irritating due to dilution and buffering.
Prolonged or repeated skin contact with undiluted product may cause mild irritation in sensitive individuals.
Allergic reactions are rare but cannot be completely excluded.
Protective gloves are recommended for workers handling the raw material.
Inhalation risk is minimal because the product has very low vapor pressure.
However, inhalation of aerosols during spraying or mixing operations may irritate the respiratory tract.
Local exhaust ventilation is recommended in manufacturing environments.
The product is not flammable and does not present explosion hazards.
In case of fire, decomposition may release nitrogen oxides and carbon oxides.
Standard firefighting procedures are sufficient.
Environmentally, AMONYL 380 BA is considered readily biodegradable under wastewater treatment conditions.
Large uncontrolled releases may increase organic load and temporarily affect aquatic oxygen levels.
Spills should be contained and prevented from entering surface waters.
For storage, it should be kept in tightly sealed containers to prevent contamination and evaporation of water.
It should be protected from freezing, which may cause phase separation or viscosity changes.
Long-term exposure to high temperatures may reduce product stability.
AMONYL 380 BA is compatible with anionic, amphoteric, and non-ionic surfactants.
It is also compatible with cationic conditioning polymers such as Polyquaternium-7 when properly formulated.
AMONYL 380 BA shows good compatibility with preservatives, fragrances, plant extracts, and common cosmetic actives.
Uses:
AMONYL 380 BAis widely used as a surfactant.
The usage of cocamidopropyl betaine in personal-care products has grown in recent years due to its relative mildness compared with other surface active compounds.
AMONYL 380 BA is widely used in various cosmetics like shampoos, bath products, and cleansing agents, shower gels, bath foam, liquid soaps, skin care products, hand wash detergents.
AMONYL 380 BA is uses in household cleaning products, the scope of HERA, include laundry detergents, hand dishwashing liquids, and hard surface cleaners.
AMONYL 380 BA is a surfactant in liquid soaps, shampoos, hair colorants, shower and bath formulations.
AMONYL 380 BA is used in cosmetics and personal hygiene products (eg, shampoos, contact lens solutions, toothpaste detergents, makeup removers, bath gels, skin care products, cleansers, liquid soaps, antiseptics, and gynecologic and anal hygiene products).
AMONYL 380 BA is used as a mild cleansing surfactant in personal care formulations.
It helps remove dirt, oil, sweat, and cosmetic residues from skin and hair.
AMONYL 380 BA is suitable for products designed for frequent daily use.
AMONYL 380 BA is commonly used as a secondary surfactant together with anionic surfactants such as SLES or sulfonates.
AMONYL 380 BA reduces the irritation potential of harsher surfactants and improves overall formulation mildness.
It also boosts foam volume and improves foam stability and creaminess.
In shampoos, it provides gentle scalp cleansing while maintaining hair softness.
AMONYL 380 BA improves manageability, reduces scalp irritation, and supports healthy scalp balance.
It is widely used in sulfate-free and sensitive-scalp shampoo formulations.
In body washes and shower gels, it improves skin comfort after rinsing and reduces dryness.
It contributes to a rich, creamy foam that enhances consumer sensory experience.
AMONYL 380 BA helps maintain the skin’s natural moisture balance during cleansing.
In facial cleansers, it allows effective removal of makeup, sunscreen, and environmental pollutants.
It maintains mildness suitable for sensitive, acne-prone, and reactive skin types.
AMONYL 380 BA supports barrier-friendly cleansing formulations.
In baby care and intimate hygiene products, it is selected for its very low irritation profile.
AMONYL 380 BA supports gentle cleansing of delicate skin and mucous membranes.
It is commonly used in tear-free and pH-balanced formulations.
In liquid hand soaps, AMONYL 380 BA improves foam quality and reduces skin dryness from frequent hand washing.
It enhances slip and smoothness of skin after use.
AMONYL 380 BA supports moisturizing soap formulations.
It also contributes to viscosity building when used with salt or polymer thickeners.
AMONYL 380 BA helps stabilize surfactant systems and improve formulation clarity.
This supports development of stable, visually appealing products.
AMONYL 380 BA is compatible with conditioning polymers, silicones, botanical extracts, and functional actives.
This allows formulation of multifunctional cleansing products with added care benefits.
It supports development of premium mild cleansing systems.
AMONYL 380 BA is used as a mild amphoteric surfactant for cleansing skin and hair.
It effectively removes sebum, sweat, particulate dirt, and cosmetic residues without excessive stripping of natural lipids.
This makes it suitable for formulations intended for frequent or daily use.
AMONYL 380 BA is commonly used as a co-surfactant together with anionic surfactants such as SLES, sulfosuccinates, or glutamates.
It reduces irritation potential, improves dermatological mildness, and enhances foam texture.
It also stabilizes foam in hard water conditions.
In shampoos, it supports gentle cleansing while improving scalp comfort and hair softness.
AMONYL 380 BA reduces itching and dryness associated with harsh surfactants.
It helps maintain natural scalp balance and supports healthier-looking hair.
AMONYL 380 BA is widely used in sulfate-free shampoos designed for sensitive scalp, colored hair, and chemically treated hair.
It improves compatibility with botanical extracts and conditioning polymers.
AMONYL 380 BA helps maintain clarity and stability in transparent formulations.
In body washes and shower gels, it improves skin feel after rinsing and reduces post-wash tightness.
AMONYL 380 BA contributes to dense, creamy foam that improves user perception of product quality.
It helps preserve the skin’s natural moisture barrier during cleansing.
Safety Profile:
AMONYL 380 BA is generally considered to have low acute toxicity when used at recommended cosmetic concentrations.
However, the concentrated raw material may cause irritation to the eyes and skin upon direct contact.
Eye exposure may result in redness, burning sensation, and excessive tearing.
Prolonged or repeated skin contact with the undiluted product may cause mild to moderate irritation in sensitive individuals.
In rare cases, allergic-type skin reactions may occur, especially in people with very sensitive skin.
Protective gloves are recommended during industrial handling.
Because the product is supplied as an aqueous liquid with very low vapor pressure, inhalation risk is minimal.
However, inhalation of aerosols or mists generated during mixing, pumping, or spraying may irritate the respiratory tract.
Adequate ventilation should be provided in production areas.
Accidental ingestion of small amounts is unlikely to cause serious health effects.
Larger amounts may cause gastrointestinal discomfort such as nausea, vomiting, or diarrhea.
Medical attention should be sought if significant quantities are swallowed.
AMONYL 380 BA is not classified as flammable and does not present an explosion hazard under normal storage and handling conditions.
In case of fire, thermal decomposition may release carbon oxides and nitrogen-containing gases.
Firefighters should use self-contained breathing apparatus in enclosed spaces.
From an environmental perspective, AMONYL 380 BA is considered readily biodegradable under wastewater treatment conditions.
