ANGELICA DAHURICA ROOT EXTRACT

Angelica Dahurica Root Extract belongs to the following substance groups
Angelica Dahurica Root Extract contains chemicals that might kill cancer cells and fungus, reduce anxiety, and settle the stomach.

Chem/IUPAC Name: Angelica Dahurica Root Extract is an extract of the roots of Angelica dahurica, Umbelliferae

SYNONYMS:
American Angelica, Angélica, Angelica acutiloba, Angelica archangelica, Angelica atropurpurea, Angelica curtisi, Angelica Dahurica, Angelica officinalis, Angelica sylvestris, Angelicae Dahuricae, Angelicae Dahuricae Radix, Angelicae Fructus, Angelicae Herba, Angelicae Radix, Angelica sylvestris, Angelicae, Angélique, Angélique Archangélique, Angélique Cultivée, Angélique de Bohème, Angélique des Jardins, Angélique Médicinale, Angélique Officinale, Angélique Sauvage, Angélique Vraie, Archangelica officinalis, Archangélique, Bai Zhi, Dang Gui (Angelica root), Du Huo, Garden Angelica, European Angelica, Herbe aux Anges, Herbe du Saint-Esprit, Japanese Angelica, Racine du Saint Esprit, Radix Angelicae, Radix Angelicae Dahuricae, Radix Angelicae Pubescentis, Root of the Holy Ghost, Wild Angelica, Wild Parsnip, Angelica dahurica root, Dahurian Angelica Root (Angelica Dahurica), Dahurian Angelica Root, Angelica dahurica root, Angelica Dahurica Root Dry Extract, Angelica Dahurica Root Extract, Angelica Dahurica Root Powder, Angelicae Dahuricae Radix, Angelicae Dahuricae Radix (Angelica Dahurica), Bai Zhi, Baizhi (Angelica Dahurica), Dahurian Angelica Root, Dahurian Angelica Root (Angelica Dahurica), Ezo Senkyu Root, Fragrant Angelica Root, O-sisi-udo Root, Udo-modaki Root, Yoroi-gusa Root, ANGELICA DAHURICA ROOT [JAN], ANGELICA DAHURICA ROOT [WHO-DD], ANGELICA DAHURICA ROOT DRY EXTRACT, ANGELICA DAHURICA ROOT EXTRACT, ANGELICA DAHURICA ROOT POWDER, ANGELICAE DAHURICAE RADIX, ANGELICAE DAHURICAE RADIX (ANGELICA DAHURICA), ANGELICAE DAHURICAE RADIX (ANGELICA DAHURICA) [CHP], BAI ZHI, BAIZHI (ANGELICA DAHURICA), DA-9805 COMPONENT ANGELICA DAHURICA ROOT, DAHURIAN ANGELICA ROOT, DAHURIAN ANGELICA ROOT (ANGELICA DAHURICA), EZO SENKYU ROOT, FRAGRANT ANGELICA ROOT, O-SISI-UDO ROOT, UDO-MODAKI ROOT, YOROI-GUSA ROOT, Dahurian Angelica, Fragrant Angelica

Angelica Dahurica Root Extract is a species of plant that is part of the Angelica family and is commonly used for medicinal purposes in the Far East. 
Angelica Dahurica Root Extract is known for its diuretic properties and is believed to possess antispasmodic, diaphoretic, expectorant, bitter aromatic, carminative, and local anti-inflammatory properties.

Angelica Dahurica Root Extract contains chemicals that might kill cancer cells and fungus, reduce anxiety, and settle the stomach.
Angelica Dahurica Root Extract belongs to the following substance groups.
Cosmetics Ingredients are subject to regulation. 

Angelica Dahurica Root Extract is extracted from the dried roots of the Umbelliferae plant Angelica dahuricae. 
Angelica Dahurica Root Extract mainly contains coumarins and volatile oil components, and has various pharmacological activities such as anti-inflammatory, analgesic, inhibiting pathogenic microorganisms, anti-tumor, and liver protection. 

One of the main active ingredients of Angelica Dahurica Root Extract is coumarins. 
Coumarin compounds can be widely used as anticoagulant and antithrombotic drugs. 
They also promote lipolysis and inhibit fat synthesis. In addition, they also have antibacterial, anti-inflammatory, antipyretic and analgesic properties. 

Angelica Dahurica Root Extract can relieve pain, relieve cough and asthma, and scavenge free radicals.
Angelica Dahurica Root Extract is also known as bai zhi, is extracted from the root of the plant  and a herbal ingredient with significant effect to inhibit melanin and whitening freckles. 

Angelica Dahurica Root Extract is an extract of the roots of Angelica dahurica.
Angelica Dahurica Root Extract, commonly known as Dahurian angelica, is a widely grown species of angelica native to Siberia, Russia Far East, Mongolia, Northeastern China, Japan, Korea, and Taiwan.

Angelica Dahurica Root Extract tends to grow near river banks, along streams and among rocky shrubs.
Angelica Dahurica Root Extract is widely used for its medicinal properties and is known to contain furanocoumarins and angelicotoxin.
Angelica Dahurica Root Extract is also commonly known as Chinese angelica, the garden angelica, root of the Holy Ghost, and wild angelica, as well as by its Chinese name, bai zhi (白芷).

Angelica Dahurica Root Extract is a perennial plant that grows to about 1–2 meters tall. 
The plant usually has a brown cylindrical root that grows approximately 2–5 cm thick.
The stem is purplish-green in color, ribbed, and it usually ranges from 2–8 cm thick in diameter. 

First year plants remain in a basal clump about 30 inches high, fuller in rich soil, with complex divided leaves 10-20 inches long, and reddish-purple coloring at the base. 
In the second or third year plant, the plant sends up a sturdy, hollow one-inch diameter stalk to 8 feet. 

The plant produces greenish-white flowers on umbels up to 12 inches in diameter that bloom in the summer, usually from July to August or September. 
The seeds of the plant follow, turning from greenish-white to medium brown and papery as they ripen from August to October.
The flowers of the plant are hermaphroditic (containing both male and female reproductive organs) and are pollinated via insects. 

The plant also undergoes self pollination. 
The roots and leaves of the plant are strongly aromatic. 
The roots have a scent resembling that of wild carrots (Daucus carota), and a pungent, bitter taste.

Angelica Dahurica Root Extract is a plant/plant extract used in some OTC (over-the-counter) products. 
Angelica Dahurica Root Extract is not an approved drug.
Angelica Dahurica Root Extract is a genus of plants and herbs that’s often used in traditional medicine, particularly in Asian countries. 

The roots of many species of Angelica Dahurica Root Extract are used to make herbal medicines.
However, Angelica Dahurica Root Extract typically refers to the species Angelica archangelica (A. archangelica). 
Angelica Dahurica Root Extract may also refer to Angelica sinensis (A. sinensis).

The roots and other parts of both of these plants have a long history of use in traditional and herbal medicine, although Angelica Dahurica Root Extract has been more thoroughly researched.
Plants in the Angelica genus grow up to 10 feet (3 meters) tall and have globe-like clusters of green or yellow flowers that blossom into small yellow fruits.

They also tend to have a strong, unique smell due to the aromatic compounds they contain. 
The scent is often described as musky, earthy, or herbaceous.
Angelica Dahurica Root Extract is known by a variety of names, including dong quai and female ginseng. 

On the other hand, Angelica Dahurica Root Extract is commonly known as wild celery or Norwegian angelica. 
This type grows mainly in European countries, where Angelica Dahurica Root Extract’s used in certain culinary applications or as an herbal medicine.
Although the name Angelica Dahurica Root Extract implies that just the root is used, most A. archangelica supplements and herbal medicine products contain the root, seeds, fruits, and/or flowers of the plant. A. sinensis products are typically only made with the root of the plant.

USES and APPLICATIONS of ANGELICA DAHURICA ROOT EXTRACT:
People use Angelica Dahurica Root Extract for indigestion, quitting smoking, excessive urination at night, decline in memory and thinking skills, rheumatoid arthritis (RA), and many other conditions, but there is no good scientific evidence to support these uses.
Angelica Dahurica Root Extract can be used in the pharmaceutical industry

Angelica Dahurica Root Extract can be used in the cosmetics industry
Angelica Dahurica Root Extract can be used in the food industry
Angelica Dahurica Root Extract is used ingredients for skincare

Angelica Dahurica Root Extract is used regulating cosmetics
Angelica Dahurica Root Extract helps to improve micro-circulation, promotes skin metabolism and delay skin ageing. 
Angelica Dahurica Root Extract has also been used in making natural skincare products such as handmade soaps, scrubs, creams, lotions, etc.

Angelica Dahurica Root Extract is used primarily for the treatment of headaches relieving the nasal obstruction, detoxification of the blood, and as a pain reliever. 
Angelica Dahurica Root Extract has been used as an anti-inflammatory, laxative, sedative, and anti-fungal cream for skin, as well as treating swollen gums and toothaches.

Angelica Dahurica Root Extract is used in traditional Chinese medicine for various purposes, including hormonal balance, digestive support, and liver detoxification.
On the other hand, Angelica Dahurica Root Extract is traditionally used in European countries for digestive problems, circulation issues, and anxiety.

Angelica Dahurica Root Extract’s native to China and other countries in East Asia, where it’s used primarily in traditional medicine to treat female hormonal issues.
This type grows mainly in European countries, where Angelica Dahurica Root Extract’s used in certain culinary applications or as an herbal medicine.

A. sinensis and Angelica Dahurica Root Extract are related, but typically only the root of the A. sinensis plant is used in herbal medicine, while the entire A. archangelica plant is used.
Angelica Dahurica Root Extract, particularly A. archangelica, has some culinary uses. 

Angelica Dahurica Root Extract’s sometimes used in the production of gin and other spirits, and the leaves can be candied to use as a garnish or decoration.
However, Angelica Dahurica Root Extract’s primarily used as an herbal remedy. 
Angelica Dahurica Root Extract has a long history of use as a traditional medicine in Europe and Russia, where it grows wild.

Angelica Dahurica Root Extract is used in traditional Chinese medicine, primarily for women’s health purposes.
Angelica Dahurica Root Extract is used for women’s health issues in traditional Chinese medicine, whereas A. archangelica is utilized in certain parts of Europe as an herbal remedy and for making spirits.

-Other uses of Angelica Dahurica Root Extract:
The stalks of Angelica Dahurica Root Extract have also been commonly used as a food ingredient. 
The stems have been made into decorative items. 

The seeds are often used as a seasoning condiment in food as well as a source of flavoring in liqueur. 
Another popular usage for this herb is its ingredient in cosmetic products.

-Medicinal uses of Angelica Dahurica Root Extract:
The medicinal properties of the Angelica Dahurica Root Extract has been dated back to Ancient China as early as 400 BC. 
Zhang Cong Zhen (1156–1228), a famous physician in the military, believed that diseases were caused by external evil factors, or pathogens, that entered the human body. 

He listed Bai Zhi as an herb that purge the body of any negative influences such as heat, clamminess, dryness, and cold on the skin.
Today, the roots are used for other numerous treatments of illnesses such as headaches, relieving nasal obstruction, detoxification of the blood, as a pain reliever, an anti-inflammatory, a laxative, sedative, anti-fungal cream for skin, as well as treating swollen gums and toothaches.

FUNCTION OF ANGELICA DAHURICA ROOT EXTRACT:
1. Effect on the central nervous system. 
A small dose of Angelica Dahurica Root Extract can excite the respiratory center, vasomotor center and vagus nerve of the oblongata, thereby enhancing breathing, raising blood pressure and slowing the pulse.

2. Hemostatic effect. 
Angelica Dahurica Root Extract has a significant effect on shortening or reducing the bleeding time, bleeding volume, coagulation time and prothrombin time of animals.

3. Effect on the uterus. 
Angelica Dahurica Root Extract has anti-estrogenic activity

4. Antibacterial effect. 
Angelica Dahurica Root Extract decoction has a certain inhibitory effect on some bacteria.

5. Anti-cancer effect. 
The water extract of Angelica Dahurica Root Extract can promote the production of interferon in the body and has anti-tumor effects.

6. Hepatoprotective effect. 
Parsley B isolated from Angelica Dahurica Root Extract has the effect of inhibiting concanavalin A-induced hepatitis.

7. Effect on skin. 
Angelica Dahurica Root Extract has an inhibitory effect on tyrosine, so it can be used for skin whitening.

WHAT DOES ANGELICA DAHURICA ROOT EXTRACT DO IN A FORMULATION?
*Skin conditioning

BENEFITS OF ANGELICA DAHURICA ROOT EXTRACT:
Angelica Dahurica Root Extract may also offer some benefits, but little research has been done on this herb. 

*Anticancer properties
In test-tube studies, Angelica Dahurica Root Extract — like A. sinensis — shows some promising anticancer and anti-tumor effects.
These effects are thought to come from angelicin and imperatorin, two powerful phytochemicals found in Angelica Dahurica Root Extract.

*Antimicrobial effects
Angelica Dahurica Root Extract may also kill harmful bacteria, viruses, and fungi.
In test-tube studies, Angelica Dahurica Root Extract essential oil can kill disease-causing bacteria like Staphylococcus aureus and Escherichia coli.

Angelica Dahurica Root Extract extract and some isolated compounds from it, including imperatorin, also exhibit antiviral activity against the herpes simplex (cold sore) virus and coxsackievirus, which causes digestive illness.
Angelica Dahurica Root Extract also shows promise as a potential food-safe preservative to inhibit mold growth, as it can kill mold that grows on walnuts.

*Anti-anxiety effects
Finally, there’s some compelling evidence from animal studies that Angelica Dahurica Root Extract may help reduce anxiety.

Summary
A. sinensis offers potential benefits for wound healing, menopause, and arthritis. Angelica Dahurica Root Extract may provide anti-anxiety and antimicrobial benefits. 
Both types can kill certain cancer cells in test-tube studies, but more research in humans is needed.

DOWNSIDES OF ANGELICA DAHURICA ROOT EXTRACT:
Angelica Dahurica Root Extract, particularly A. sinensis, has known side effects and may cause some drug interactions. 
While Angelica Dahurica Root Extract may likewise have some potential side effects, it has not been studied as much as A. sinensis.

There have been suspected cases of high dose Angelica Dahurica Root Extract supplements causing heart problems. A. sinensis may also increase your blood pressure.

Angelica Dahurica Root Extract may likewise interact with blood thinners like warfarin, possibly causing dangerous and potentially fatal bleeding in certain instances. 
If you’re taking a blood thinner, you should not use Angelica Dahurica Root Extract without first clearing it with your healthcare provider.

Additionally, members of the Angelica genus contain furanocoumarins, which are the same compounds in grapefruit that may interact with many drugs, including certain cholesterol and anti-seizure medications.
Talk to your healthcare provider before supplementing with any type of Angelica if you’re taking prescription medications that carry a grapefruit warning.

Furthermore, know that photodermatitis, which is an abnormal skin response to ultraviolet (UV) rays, and contact dermatitis are also a concern when handling the angelica plant.

Finally, due to a lack of evidence regarding their safety in pregnant and breastfeeding women, you should avoid taking Angelica Dahurica Root Extract and A. sinensis if you’re pregnant, trying to become pregnant, or breastfeeding.

Summary
Angelica Dahurica Root Extract may increase your blood pressure, cause heart problems, and interact with blood thinners. 
Additionally, plants in the Angelica genus may interact with drugs that carry a grapefruit warning.

TYPE OF PREPARATION OF ANGELICA DAHURICA ROOT EXTRACT:
Extract (solvent extract)

FUNCTIONS OF ANGELICA DAHURICA ROOT EXTRACT IN COSMETIC PRODUCTS:
*SKIN CONDITIONING
Angelica Dahurica Root Extract maintains the skin in good condition

PROPAGATION OF ANGELICA DAHURICA ROOT EXTRACT:
In an ideal climate, most species of Angelica Dahurica Root Extract, including the dahurican root, can thrive in moist and shady environments, at the same time where sun is accessible when necessary.

It is best to plant fresh seeds of this plant once available. 
Once the seeds have ripened, its color brown and texture papery, they are immediately sown in a cold frame in deep, moist, fertile soil. 

Though the plants can grow under semi-shade or full-shaded conditions, the seeds require light for it to germinate. 
In addition, since this is a perennial plant, seeds are not required for its growth. A. dahurica can grow back naturally on its own, year after year.
The Dahurican roots are primarily produced in China's Sichuan province, in the Suining district.

CULTIVATION OF ANGELICA DAHURICA ROOT EXTRACT:
The Dahurican roots are harvested twice a year during the summer and autumn seasons. 
Its cylindrical roots must be harvested before the plant's stalk emerges. 
The leaves are removed, the side roots are trimmed, and the roots are thinly sliced, longitudinally. 

Afterwards, the sliced roots are dried under the sun.
In Suining, 70% of its usage are for general purposes whereas 100% of its usage are for medicinal purposes. 
The roots are also harvested and cultivated in Taiwan, Japan, and Korea.

BENEFITS OF ANGELICA DAHURICA ROOT EXTRACT:
Overall, there’s very little scientific evidence regarding the benefits of Angelica Dahurica Root Extract — neither A. sinensis nor A. archangelica.

A. sinensis benefits
Angelica Dahurica Root Extract’s thought that most of the potential benefits of A. sinensis come from ligustilide, a powerful compound that comprises approximately 1% of the plant and provides much of its strong fragrance.

*Wound healing
Angelica Dahurica Root Extract may promote wound healing by encouraging angiogenesis, or the creation of new blood vessels.
There’s also some early evidence that Angelica Dahurica Root Extract can specifically promote the healing of diabetic foot wounds. 
These can be more severe and slower to heal than other wounds due to the blood vessel and tissue damage that high blood sugar levels cause.

*Relief of menopausal hot flashes
One of the most common uses of A. sinensis, especially in traditional Chinese medicine, is the management of menopausal symptoms and other female hormonal issues.

Complementary therapies are also growing in popularity, as more people seek out natural options for menopause symptoms like hot flashes or night sweats.
Some evidence suggests that decreasing levels of serotonin in the body can contribute to menopausal hot flashes, and Angelica Dahurica Root Extract may help maintain or increase circulating levels of serotonin — thereby reducing the severity and frequency of hot flashes.

Still, there’s very little high quality evidence to support the use of Angelica Dahurica Root Extract for menopause symptoms, nor any long-term evidence of its safety in menopausal women.

*Arthritis relief
Angelica Dahurica Root Extract may provide protection against both osteoarthritis, or joint “wear and tear,” as well as rheumatoid arthritis (RA), an inflammatory, autoimmune condition of the joints.

Supplementing with Angelica Dahurica Root Extract may decrease inflammation, prevent further joint damage, and promote cartilage repair in osteoarthritis.
Angelica Dahurica Root Extract may decrease the inflammatory response, reducing pain and improving some of its other symptoms.

PHYSICAL and CHEMICAL PROPERTIES of ANGELICA DAHURICA ROOT EXTRACT:
Pharmacodynamics: Not Available
Mechanism of action: Not Available
Absorption: Not Available
Volume of distribution: Not Available
Protein binding: Not Available
Metabolism: Not Available
Route of elimination: Not Available
Half-life: Not Available
Clearance: Not Available

FIRST AID MEASURES of ANGELICA DAHURICA ROOT EXTRACT:
-Description of first-aid measures
*General advice:
Show this material safety data sheet to the doctor in attendance.
*If inhaled:
After inhalation: 
Fresh air.
*In case of skin contact: 
Take off immediately all contaminated clothing. 
Rinse skin with
water/ shower.
*In case of eye contact:
After eye contact: 
Rinse out with plenty of water. 
Call in ophthalmologist. 
Remove contact lenses.
*If swallowed:
After swallowing: 
Immediately make victim drink water (two glasses at most). 
Consult a physician.
-Indication of any immediate medical attention and special treatment needed.
No data available

ACCIDENTAL RELEASE MEASURES of ANGELICA DAHURICA ROOT EXTRACT:
-Environmental precautions:
Do not let product enter drains.
-Methods and materials for containment and cleaning up:
Cover drains. 
Collect, bind, and pump off spills. 
Observe possible material restrictions. 
Take up dry. 
Dispose of properly. 
Clean up affected area.

FIRE FIGHTING MEASURES of ANGELICA DAHURICA ROOT EXTRACT:
-Extinguishing media:
*Suitable extinguishing media:
Carbon dioxide (CO2) 
Foam 
Dry powder
*Unsuitable extinguishing media:
For this substance/mixture no limitations of extinguishing agents are given.
-Further information:
Prevent fire extinguishing water from contaminating surface water or the ground water system.

EXPOSURE CONTROLS/PERSONAL PROTECTION of ANGELICA DAHURICA ROOT EXTRACT:
-Control parameters:
--Ingredients with workplace control parameters:
-Exposure controls:
--Personal protective equipment:
*Eye/face protection:
Use equipment for eye protection. 
Safety glasses
*Body Protection:
protective clothing
*Respiratory protection:
Recommended Filter type: Filter A 
-Control of environmental exposure:
Do not let product enter drains.

HANDLING and STORAGE of ANGELICA DAHURICA ROOT EXTRACT:
-Conditions for safe storage, including any incompatibilities:
*Storage conditions:
Tightly closed. 
Dry.

STABILITY and REACTIVITY of ANGELICA DAHURICA ROOT EXTRACT:
-Chemical stability:
The product is chemically stable under standard ambient conditions (room temperature) .
-Possibility of hazardous reactions:
No data available