Quick Search
Botanical Classification and Nomenclature
Scientific Name: Arctium majus (Gaertn.) Bernh.
Family: Asteraceae (Compositae)
Common Names: Greater Burdock, Lappa major, Bardana mayor
Synonyms: Arctium lappa subsp. majus, Lappa major, Arctium vulgare, Arctium officinale
Arctium majus is a biennial plant native to Europe and Asia, characterized by its large, cordate leaves and purple, globular flower heads.
The plant produces a fleshy taproot that can grow up to 1 meter in length, which is utilized for its medicinal and nutritional properties.
Chemical Composition
The root of Arctium majus contains a variety of bioactive compounds:
Polysaccharides: Inulin, a prebiotic fiber that contributes to the extract's detoxifying properties.
Phenolic Acids: Caffeic acid and chlorogenic acid, known for their antioxidant benefits.
Lignans: Arctiin and arctigenin, which exhibit potential anticancer and hormone-regulating activities.
Sesquiterpene Lactones: Including lappaol F, contributing to anti-inflammatory effects.
Flavonoids: Providing additional antioxidant and anti-inflammatory benefits.
Fatty Acids: Such as linoleic acid, supporting skin health.
Sterols: Phytosterols that aid in maintaining skin barrier function.
These compounds collectively contribute to the plant's therapeutic effects and applications in various health-related fields.
Pharmacological Properties
Arctium majus has been studied for various therapeutic effects:
Anti-inflammatory: Reduces inflammation, beneficial in conditions like acne and eczema.
Antioxidant: Scavenges free radicals, protecting cells from oxidative stress.
Antimicrobial: Exhibits activity against bacteria and fungi.
Antidiabetic: May help regulate blood sugar levels.
Hepatoprotective: Protects liver cells from damage.
Anticancer: Compounds like arctigenin show potential in inhibiting tumor growth.
Skin Health: Improves skin texture and reduces wrinkles by enhancing extracellular matrix metabolism.
These pharmacological properties make Arctium majus a valuable candidate for therapeutic applications in various medical and cosmetic fields.
Applications
Cosmetic and Dermatological Uses
Due to its skin-conditioning properties, Arctium majus root extract is incorporated into various cosmetic products:
Acne Treatments: Incorporated in creams and serums to reduce acne lesions.
Anti-aging Products: Used in formulations aimed at reducing wrinkles and improving skin elasticity.
Scalp Care: Added to shampoos and conditioners to promote healthy hair growth and reduce dandruff.
Traditional Medicine
In traditional medicine, Arctium majus is utilized for:
Detoxification: Acts as a blood purifier.
Digestive Health: Alleviates symptoms of indigestion.
Skin Conditions: Treats ailments like psoriasis and eczema.
Pharmaceutical Formulations
The extract is used in the development of:
Topical Ointments: For treating skin inflammations and infections.
Oral Supplements: As a supportive treatment for metabolic disorders.
Regulatory Status
CAS Number: 84649-87-6
ECHA EC Number: 283-468-0
FDA UNII: Not assigned
INCI Name: Arctium Majus Root Extract
CosIng Reference: 54486
These identifiers are used for regulatory and safety assessments in various regions.
Conclusion
Arctium majus is a botanically rich species with a wide range of pharmacological activities.
Its chemical constituents contribute to its therapeutic effects, making it valuable in both traditional and modern medicine.
Ongoing research continues to explore its full potential in various health applications.
SAFETY INFORMATION ABOUT ARCTIUM MAJUS
First aid measures:
Description of first aid measures:
General advice:
Consult a physician.
Show this safety data sheet to the doctor in attendance.
Move out of dangerous area:
If inhaled:
If breathed in, move person into fresh air.
If not breathing, give artificial respiration.
Consult a physician.
In case of skin contact:
Take off contaminated clothing and shoes immediately.
Wash off with soap and plenty of water.
Consult a physician.
In case of eye contact:
Rinse thoroughly with plenty of water for at least 15 minutes and consult a physician.
Continue rinsing eyes during transport to hospital.
If swallowed:
Do NOT induce vomiting.
Never give anything by mouth to an unconscious person.
Rinse mouth with water.
Consult a physician.
Firefighting measures:
Extinguishing media:
Suitable extinguishing media:
Use water spray, alcohol-resistant foam, dry chemical or carbon dioxide.
Special hazards arising from the substance or mixture
Carbon oxides, Nitrogen oxides (NOx), Hydrogen chloride gas
Advice for firefighters:
Wear self-contained breathing apparatus for firefighting if necessary.
Accidental release measures:
Personal precautions, protective equipment and emergency procedures
Use personal protective equipment.
Avoid breathing vapours, mist or gas.
Evacuate personnel to safe areas.
Environmental precautions:
Prevent further leakage or spillage if safe to do so.
Do not let product enter drains.
Discharge into the environment must be avoided.
Methods and materials for containment and cleaning up:
Soak up with inert absorbent material and dispose of as hazardous waste.
Keep in suitable, closed containers for disposal.
Handling and storage:
Precautions for safe handling:
Avoid inhalation of vapour or mist.
Conditions for safe storage, including any incompatibilities:
Keep container tightly closed in a dry and well-ventilated place.
Containers which are opened must be carefully resealed and kept upright to prevent leakage.
Storage class (TRGS 510): 8A: Combustible, corrosive hazardous materials
Exposure controls/personal protection:
Control parameters:
Components with workplace control parameters
Contains no substances with occupational exposure limit values.
Exposure controls:
Appropriate engineering controls:
Handle in accordance with good industrial hygiene and safety practice.
Wash hands before breaks and at the end of workday.
Personal protective equipment:
Eye/face protection:
Tightly fitting safety goggles.
Faceshield (8-inch minimum).
Use equipment for eye protection tested and approved under appropriate government standards such as NIOSH (US) or EN 166(EU).
Skin protection:
Handle with gloves.
Gloves must be inspected prior to use.
Use proper glove
removal technique (without touching glove's outer surface) to avoid skin contact with this product.
Dispose of contaminated gloves after use in accordance with applicable laws and good laboratory practices.
Wash and dry hands.
Full contact:
Material: Nitrile rubber
Minimum layer thickness: 0.11 mm
Break through time: 480 min
Material tested:Dermatril (KCL 740 / Aldrich Z677272, Size M)
Splash contact
Material: Nitrile rubber
Minimum layer thickness: 0.11 mm
Break through time: 480 min
Material tested:Dermatril (KCL 740 / Aldrich Z677272, Size M)
It should not be construed as offering an approval for any specific use scenario.
Body Protection:
Complete suit protecting against chemicals, The type of protective equipment must be selected according to the concentration and amount of the dangerous substance at the specific workplace.
Respiratory protection:
Where risk assessment shows air-purifying respirators are appropriate use a fullface respirator with multi-purpose combination (US) or type ABEK (EN 14387) respirator cartridges as a backup to engineering controls.
If the respirator is the sole means of protection, use a full-face supplied air respirator.
Use respirators and components tested and approved under appropriate government standards such as NIOSH (US) or CEN (EU).
Control of environmental exposure
Prevent further leakage or spillage if safe to do so.
Do not let product enter drains.
Discharge into the environment must be avoided.
Stability and reactivity:
Chemical stability:
Stable under recommended storage conditions.
Incompatible materials:
Strong oxidizing agents:
Hazardous decomposition products:
Hazardous decomposition products formed under fire conditions.
Carbon oxides, Nitrogen oxides (NOx), Hydrogen chloride gas.
Disposal considerations:
Waste treatment methods:
Product:
Offer surplus and non-recyclable solutions to a licensed disposal company.
Contact a licensed professional waste disposal service to dispose of this material.
Contaminated packaging:
Dispose of as unused product
