BANABA (LAGERSTROEMIA SPECIOSA) EXTRACT

Banaba (Lagerstroemia Speciosa) Extract is derived from the leaves of the Banaba plant, also known as Lagerstroemia speciosa, which is native to Southeast Asia. 
Banaba (Lagerstroemia Speciosa) Extract has been traditionally used as a medicinal herb and is now commonly used as a dietary supplement due to its potential health benefits.

CAS Number: 94586-45-5
EC Number: 302-605-0
Botanical Name: Lagerstroemia speciosa
Scientific Name(s): Lagerstroemia speciosa (L.) Pers.

SYNONYMS:
Banaba Leaves, Banaba Extract, Banabalean, Corosolic acid, Crape Myrtle, Crepe Myrtle, Extrait de Banaba, Lagerstroemia flos-reginae, Lagerstroemia speciosa, Munchausia speciosa, Myrte de Crêpe, Pride-of-India, Pyinma, Queen's Crape Myrtle, Banaba, Crepe myrtle, Pride of India, Queen's crepe myrtle, Queen's flower, Lagerstroemia speciosa Extract, Banaba Leaf Extract, Banaba Tea Extract, Queen's Flower Extract, Lagerstroemia Extract, Banaba Bark Extract, and Pride of India Extract

Banaba (Lagerstroemia Speciosa) Extract comes from the banaba bush, or Lagerstroemia speciosa, an ornamental plant indigenous to Australia, Southeast Asia, and India. 
Banaba (Lagerstroemia Speciosa) is a type of crepe myrtle that grows in India, the Philippines, and Southeast Asia. 

Banaba (Lagerstroemia Speciosa) Extract's leaves have been used to treat diabetes in folk medicine for centuries.
In addition to their anti-diabetic properties, Banaba (Lagerstroemia Speciosa) Extract leaves offer health benefits, such as antioxidant, cholesterol-lowering, and anti-obesity effects.

Banaba (Lagerstroemia Speciosa) Extract is a medium-sized tree. 
Banaba (Lagerstroemia Speciosa) Extract is derived from the leaves of the Banaba plant, also known as Lagerstroemia speciosa, which is native to Southeast Asia. 

Banaba (Lagerstroemia Speciosa) Extract has been traditionally used as a medicinal herb and is now commonly used as a dietary supplement due to its potential health benefits. 
Banaba (Lagerstroemia Speciosa) Extract contains corosolic acid, which is believed to have anti-diabetic and antioxidant effects, as well as potential benefits for weight management and heart health.

Banaba (Lagerstroemia Speciosa) Extract is derived from the leaves of the Banaba plant, also known as Lagerstroemia speciosa, which is native to Southeast Asia. 
Banaba (Lagerstroemia Speciosa) Extract has been traditionally used as a medicinal herb and is now commonly used as a dietary supplement due to its potential health benefits. 

Banaba (Lagerstroemia Speciosa) Extract contains corosolic acid, which is believed to have anti-diabetic and antioxidant effects, as well as potential benefits for weight management and heart health.
Banaba (Lagerstroemia Speciosa) Extract, or Lagerstroemia speciosa, is a tree, which belongs to the genus Lagerstroemia, also known as Crape Myrtle. 

The leaves contain more than 40 beneficial compounds, of which corosolic acid and ellagic acid are the prime with potent anti-oxidant activities.
Banaba (Lagerstroemia Speciosa) Extract is a brown coloured powder which has traditionally been used in the treatment of many conditions such as diabetes.
Banaba (Lagerstroemia Speciosa) Extract is a species of crepe myrtle tree that is native to the Philippines and Southeast Asia. 

People use the leaves of Banaba (Lagerstroemia Speciosa) Extract to make medicine.
Banaba, or Lagerstroemia speciosa, is a tree, which belongs to the genus Lagerstroemia, also known as Crape Myrtle. 
The leaves contain more than 40 beneficial compounds, of which corosolic acid and ellagic acid are the prime with potent anti-oxidant activities.

Banaba (Lagerstroemia Speciosa) Extract is an herbal remedy extracted from the leaves of Lagerstroemia speciosa, a tree native to Southeast Asia. 
Long used in folk medicine, Banaba (Lagerstroemia Speciosa) Extract is now available in supplement form. 
Proponents claim that Banaba (Lagerstroemia Speciosa) Extract can promote weight loss and treat a wide range of health problems.

Banaba (Lagerstroemia Speciosa) Extract contains corosolic acid, a substance shown to possess antioxidant, anti-inflammatory, antiviral, antifungal, and blood-sugar-lowering properties.
Banaba (Lagerstroemia Speciosa) Extract also contains ellagitannins, a class of compounds that act as antioxidants.

Banaba (Lagerstroemia Speciosa) Extract (Family: Lythraceae) is native to Asia-tropical and subtropical regions. 
The phytochemical investigation of Banaba (Lagerstroemia Speciosa) Extract and fruit revealed that it contained steroids, terpenoids, glycosides, phenolic compounds, α-amino acids, saponins, starch, alkaloids, carbohydrates, organic acids, flavonoids, reducing sugars, tannins and many other active metabolites. 

Banaba (Lagerstroemia Speciosa) Extract possessed many Pharmacological effects included antimicrobial, antioxidant, anticancer, antidiabetic, hypolipidemic, antiobesity, anti-inflammatory, analgesic, gastrointestinal, diuretic, thrombolytic, cardiovascular, central nervous, inhibition of TNFα production, xanthine oxidase inhibitition, hepatoprotective and nephroprotective effects. 
The current review discussed the chemical constituents, pharmacological and therapeutic effects of Banaba (Lagerstroemia Speciosa) Extract.

USES and APPLICATIONS of BANABA (LAGERSTROEMIA SPECIOSA) EXTRACT:
Banaba (Lagerstroemia Speciosa) Extract is also found in other warm climates throughout the world including the temperate regions of the United States, where it is commonly known as crepe myrtle. 
In addition to its use as a decorative shrub, the Banaba (Lagerstroemia Speciosa) Extract bush has been prized for its medicinal properties. 

Banaba (Lagerstroemia Speciosa) Extract contains high levels of a plant insuli known as corosolic acid. 
Studies have shown that the corosolic acid naturally present in Banaba (Lagerstroemia Speciosa) Extract may improve blood sugar control in type II diabetics.

The leaves of Banaba (Lagerstroemia Speciosa) Extract are used as medicine.
Banaba (Lagerstroemia Speciosa) Extract might reduce blood sugar and help the body use insulin more efficiently.

People use Banaba (Lagerstroemia Speciosa) Extract for prediabetes, diabetes, and other conditions, but there is no good scientific evidence to support these uses.
Banaba (Lagerstroemia Speciosa) Extract is used for diabetes and weight loss.

-Application of Banaba Leaf Extract:
*Diabetes management: 
Banaba (Lagerstroemia Speciosa) Extract is believed to help regulate blood sugar levels and may be useful for people with type 2 diabetes.

*Weight management: 
Some studies have suggested that Banaba (Lagerstroemia Speciosa) Extract may help support weight loss and control appetite.

*Antioxidant properties: 
Banaba (Lagerstroemia Speciosa) Extract is rich in antioxidants, which help protect the body against damage from harmful molecules known as free radicals.

*Heart health: 
Some evidence suggests that Banaba (Lagerstroemia Speciosa) Extract may help improve cardiovascular health by reducing cholesterol levels and improving blood circulation.

*Inflammation: 
Banaba (Lagerstroemia Speciosa) Extract has anti-inflammatory properties, which may help reduce swelling and pain.

-Uses of Banaba (Lagerstroemia Speciosa) Extract
*Diabetes. 
Some early research suggests that taking a particular Banaba (Lagerstroemia Speciosa) Extract (Glucosol) for 2 weeks lowers blood sugar by 10% in people with type 2 diabetes. 

However, other early research suggests that taking a single dose of corosolic acid, a chemical in Banaba (Lagerstroemia Speciosa) Extract, before eating does not improve post-meal sugar tolerance.

*Weight loss.
Other conditions.
More evidence is needed to rate the effectiveness of Banaba (Lagerstroemia Speciosa) Extract for these uses.

CLINICAL OVERVIEW OF BANABA (LAGERSTROEMIA SPECIOSA) EXTRACT:
Banaba (Lagerstroemia Speciosa) Extract preparations have been used in Philippine folk medicine for treatment of diabetes; however, reviews of medical literature on the effects of banaba in diabetes have identified few quality clinical trials and some open-label or small studies. 
Clinical trial data are lacking to recommend Banaba (Lagerstroemia Speciosa) Extract for any indication.

HEALTH BENEFITS OF BANABA (LAGERSTROEMIA SPECIOSA) EXTRACT:
*Control blood sugar
*Weight management
*Protects liver from disease
*Remedy for relieving viral infection
*As an anti infective agent
*Cures Gout
*Treating poor kidney Health
*Combats digestive issues

OTHER POTENTIAL BENEFITS OF BANABA (LAGERSTROEMIA SPECIOSA) EXTRACT:
Banaba (Lagerstroemia Speciosa) Extract may provide other potential benefits, such as:
*Anticancer effects. 
Test-tube studies suggest that Banaba (Lagerstroemia Speciosa) Extract may promote the programmed cell death of lung and liver cancer cells.

*Antibacterial and antiviral potential. 
Banaba (Lagerstroemia Speciosa) Extract may protect against bacteria like Staphylococcus aureus and Bacillus megaterium, as well as viruses like the anti-human rhinovirus (HRV), a cause of the common cold.

*Antithrombotic effect. 
Blood clots often lead to high blood pressure and stroke, and Banaba (Lagerstroemia Speciosa) Extract may help dissolve them.

*Protection against kidney damage. 
Antioxidants in Banaba (Lagerstroemia Speciosa) Extract may protect the kidneys from damage caused by chemotherapy drugs 

ORIGIN AND USES OF BANABA (LAGERSTROEMIA SPECIOSA) EXTRACT:
Banaba (Lagerstroemia Speciosa) Extract, or Lagerstroemia speciosa, is a tree native to tropical Southeast Asia. 
Banaba (Lagerstroemia Speciosa) Extract belongs to the genus Lagerstroemia, also known as Crape Myrtle.

The tree is widely distributed in India, Malaysia, and the Philippines, where it’s known as Jarul, Pride of India, or Giant Crape Myrtle.
Almost every part of the tree offers medicinal properties. 
For example, the bark is often used to treat diarrhea, while its root and fruit extracts are believed to have an analgesic, or pain-relieving, effect.

The leaves contain over 40 beneficial compounds, of which corosolic acid and ellagic acid stand out. Though the leaves offer a variety of benefits, their ability to lower blood sugar levels appears the most potent and sought after.

Summary
Banaba leaves come from the tree of the same name. 
They contain over 40 bioactive compounds and offer multiple health benefits, including the ability to lower blood sugar levels.

ANTIOXIDANT ACTIVITY OF BANABA (LAGERSTROEMIA SPECIOSA) EXTRACT:
Antioxidants are compounds that counteract the harmful effects of free radicals. 
These effects could otherwise negatively affect DNA, fat, and protein metabolism and promote disease.

Furthermore, antioxidants protect your pancreas from free-radical damage — an additional antidiabetic effect.
Banaba (Lagerstroemia Speciosa) Extract can neutralize free radicals due to their high content of antioxidants like phenols and flavonoids, as well as quercetin and corosolic, gallic, and ellagic acids.

One 15-day study in rats found that 68 mg per pound (150 mg per kg) of body weight of Banaba (Lagerstroemia Speciosa) Extract neutralized free radicals and other reactive species while regulating levels of antioxidant enzymes.
Still, human studies on the antioxidant effects of Banaba (Lagerstroemia Speciosa) Extract are lacking.

BANABA (LAGERSTROEMIA SPECIOSA) EXTRACT MAY OFFER ANTI-OBESITY BENEFITS: 
Obesity affects about 40–45% of American adults, and it’s a risk factor for chronic disease.
Recent studies have linked Banaba (Lagerstroemia Speciosa) Extract with anti-obesity activity, as they may inhibit adipogenesis and lipogenesis — the formation of fat cells and fat molecules, respectively.

Also, polyphenols in the leaves, such as pentagalloylglucose (PGG), may prevent fat cell precursors from transforming into mature fat cells.
However, most research on this topic was conducted in test tubes, so human studies are needed.

BANABA (LAGERSTROEMIA SPECIOSA) EXTRACT MAY REDUCE HEART DISEASE RISK FACTORS:
High blood cholesterol is a key risk factor for heart disease — the leading cause of death in America and third leading cause of mortality worldwide.
Human studies suggest that corosolic acid and PGG in Banaba (Lagerstroemia Speciosa) Extract may help lower blood cholesterol and triglycerides levels.

In one 10-week study in mice fed a high cholesterol diet, those treated with corosolic acid showed a 32% reduction in blood cholesterol and a 46% reduction in liver cholesterol levels, compared with a control group.

Similarly, a 10-week study in 40 adults with impaired fasting glucose found that a combination of Banaba (Lagerstroemia Speciosa) Extract and turmeric extracts reduced triglyceride levels by 35% and increased HDL (good) cholesterol levels by 14%.
While these results are promising, research on the direct effects of Banaba (Lagerstroemia Speciosa) Extract on blood cholesterol levels is still needed.

HOW DOES BANABA (LAGERSTROEMIA SPECIOSA) EXTRACT WORK?
Banaba (Lagerstroemia Speciosa) Extract seems to lower blood glucose in people with type 2 diabetes, according to very preliminary research. 
Banaba (Lagerstroemia Speciosa) Extract might help the body use insulin more efficiently.

POSSIBLE BENEFITS OF BANABA (LAGERSTROEMIA SPECIOSA) EXTRACT:
Research suggests that banaba leaves have various medicinal properties.

*May help control blood sugar levels
The antidiabetic effect of banaba leaves is one reason why they’re popular.
Researchers attribute this effect to several compounds, namely corosolic acid, ellagitannins, and gallotannins.

Corosolic acid lowers blood sugar levels by increasing insulin sensitivity, enhancing glucose uptake, and inhibiting alpha-glucosidase — an enzyme that helps digest carbs. 
That’s why it’s claimed to have an insulin-like effect.

Insulin is the hormone that regulates blood sugar levels. 
In people with type 2 diabetes, insulin resistance increases the demand for this hormone. 
However, the pancreas may not be able to meet those demands, resulting in high blood sugar levels.

In one study in 31 adults, those who received a capsule containing 10 mg of corosolic acid had lower blood sugar levels for 1–2 hours after performing an oral glucose tolerance test, compared with those in a control group.

In addition to corosolic acid, ellagitannins — namely lagerstroemin, flosin B, and reginin A — also improve blood sugar levels.
They promote glucose uptake by activating glucose transporter type 4 (GLUT4), a protein that transports glucose from the bloodstream into muscle and fat cells.

Likewise, gallotanins seem to stimulate the transportation of glucose into cells. 
It’s even hypothesized that a type of gallotanin called penta-O-galloyl-glucopyranose (PGG) has higher stimulatory activity than corosolic acid and ellagitannins.

While studies have found promising results on the anti-diabetic properties of banaba leaves, most have used a combination of herbs or compounds. 
Thus, further studies on the leaves alone are needed to better understand their blood sugar-lowering effects

BENEFITS OF
*Diabetes Management
*Weight Loss
*Anti-oxidant & Anti-microbial
*Boosts Heart Health

PHYSICAL and CHEMICAL PROPERTIES of BANABA (LAGERSTROEMIA SPECIOSA) EXTRACT:
Product Name: Banaba Extract
CAS Number: 94586-45-5
EC Number: 302-605-0
Botanical Name: Lagerstroemia speciosa
Appearance: Light brown to dark brown powder
Odor: Characteristic herbal odor
Solubility: Soluble in water and ethanol
Molecular Weight: Not applicable
Density: Not applicable
Boiling Point: Not applicable
Melting Point: Not applicable
Molecular Formula: Not applicable
MSDS (Material Safety Data Sheet): Available from the supplier
Flash Point: Not applicable

FIRST AID MEASURES of BANABA (LAGERSTROEMIA SPECIOSA) EXTRACT:
 -Description of first-aid measures
*General advice:
Show this material safety data sheet to the doctor in attendance.
*If inhaled:
After inhalation: 
Fresh air.
*In case of skin contact: 
Take off immediately all contaminated clothing. 
Rinse skin with
water/ shower.
*In case of eye contact:
After eye contact: 
Rinse out with plenty of water. 
Call in ophthalmologist. 
Remove contact lenses.
*If swallowed:
After swallowing: 
Immediately make victim drink water (two glasses at most). 
Consult a physician.
-Indication of any immediate medical attention and special treatment needed.
No data available

ACCIDENTAL RELEASE MEASURES of BANABA (LAGERSTROEMIA SPECIOSA) EXTRACT:
-Environmental precautions:
Do not let product enter drains.
-Methods and materials for containment and cleaning up:
Cover drains. 
Collect, bind, and pump off spills. 
Observe possible material restrictions. 
Take up dry. 
Dispose of properly. 
Clean up affected area.

FIRE FIGHTING MEASURES of BANABA (LAGERSTROEMIA SPECIOSA) EXTRACT:
-Extinguishing media:
*Suitable extinguishing media:
Carbon dioxide (CO2) 
Foam 
Dry powder
*Unsuitable extinguishing media:
For this substance/mixture no limitations of extinguishing agents are given.
-Further information:
Prevent fire extinguishing water from contaminating surface water or the ground water system.

EXPOSURE CONTROLS/PERSONAL PROTECTION of BANABA (LAGERSTROEMIA SPECIOSA) EXTRACT:
-Control parameters:
--Ingredients with workplace control parameters:
-Exposure controls:
--Personal protective equipment:
*Eye/face protection:
Use equipment for eye protection. 
Safety glasses
*Body Protection:
protective clothing
*Respiratory protection:
Recommended Filter type: Filter A 
-Control of environmental exposure:
Do not let product enter drains.

HANDLING and STORAGE of BANABA (LAGERSTROEMIA SPECIOSA) EXTRACT:
-Conditions for safe storage, including any incompatibilities:
*Storage conditions:
Tightly closed. 
Dry.

STABILITY and REACTIVITY of BANABA (LAGERSTROEMIA SPECIOSA) EXTRACT:
-Chemical stability:
The product is chemically stable under standard ambient conditions (room temperature) .
-Possibility of hazardous reactions:
No data available