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Bayberry extract is derived from the bark of the bayberry tree (Myrica cerifera), a plant native to North America.
Bayberry extract is known for its use in traditional medicine and various applications due to its bioactive compounds.
Bayberry extract is a kind of flavonols compounds, which extracted from the bark of myricaceae plant.
CAS Number: 529-44-2
Molecular Formula: C15H10O8
Molecular Weight: 318.24
EINECS Number: 208-463-2
Synonyms: DivK1c_006627, Myricetin, analytical standard, SPBio_002509, BPBio1_000628, MEGxp0_000357, DTXSID8022400, ACon1_000267, BDBM15236, cid_5281672, GTPL13074, KBio1_001571, KBio2_001981, KBio2_004549, KBio2_007117, 2o63, CHEBI: 18152, REGID_for_CID_5281672, HMS1569M12, HMS2096M12, HMS2231L04, HMS3262C22, HMS3656I05, Myricetin - CAS 529-44-2, BCP28295, Myricetin, >=96.0% (HPLC), Myricetin, >=96.0%, crystalline, TNP00286, Tox21_500740, HB0434, LMPK12110001, s2326, STL284709, 3,7,3',4',5'-Hexahydroxyflavone, AKOS015903103, AC-4533, CCG-204825, CS-6221, DB02375, KS-5268, LP00740, SDCCGSBI-0050718.P003, 3,3',4',5,5',7-hexOH-Flavone, Flavone,3',4',5,5',7-hexahydroxy-, NCGC00015697-01, NCGC00015697-02, NCGC00015697-03, NCGC00015697-04, NCGC00015697-05, NCGC00015697-06, NCGC00015697-07, NCGC00015697-08, NCGC00015697-09, NCGC00015697-10, NCGC00015697-11, NCGC00015697-12, NCGC00015697-13.
Bayberry extract is a shrub that grows in Texas and the eastern US.
The root bark and berries are used to make medicine.
Despite safety concerns, Bayberry extract is used for colds, diarrhea, nausea, skin wounds, and many other conditions, but there is no good scientific evidence to support these uses.
In manufacturing, the wax Bayberry extract taken from the berries is used in fragrances and candles.
Waxberry is one of the subtropical fruit trees native to China, and The growth history of wild has been over 7000 years, and artificial cultivation has more than 2000 years.
There are very rich resources of the bark of myricaceae in Eastern China, hunan, guangdong, guangxi, guizhou and other regions, but the trimmed discarded arbutus tree branches can be as a large number of plant sources for a long time.
But due to reasons such as extraction process, the current study of arbutus pigment mainly comes from the vine tea, source of strawberry tree is very little.
And cany tea mainly comes from dihydrogen arbutus pigment and limited resources, and has the limitation to the long-term development and utilization on myricetin.
Bayberry extract is used as antibacterial and anti-inflammatory drugs, and arbutus pigment and arbutus glucosidethe are contained in the red bayberry bark.
At home and abroad in recent years, studies have shown that Bayberry extract has a variety of activities.
Antagonism of platelet activating factor(PAF), fall blood sugar function, antioxidation, protect liver function, the solution of light alcohol poisoning, the active ingredient Bayberry extract bark and leaves has the proven pharmacological effects, also has anti-inflammatory, antitumor, resistance mutation, prevention of dental caries, oxidation resistance, elimination of free radicals and other pharmacological activities.
Bayberry extract is a kind of flavonoids which extracted from the fruits of arbutus, has scavenging free radicals, antioxidation, antitumor, reduces nerve toxicity, affects lymphocyte activation and proliferation, platelet activating factor, reduces blood sugar, removes alcohol, prevention of alcoholic liver, fatty liver, liver cell deterioration, reduces the incidence of liver cancer, protects liver to protect liver, anti-inflammatory and other functions.
Bayberry extract has a protection of liver, reduction enzyme and retreat yellow, strengthen the nonspecific immune function in mice and immunocompromised mice humoral immune function, thus protect liver function.
Bayberry extract can take carbon tetrachloride, D2 galactosamine and isothiocyanate naphthalene ester to acute liver injury in mice model, observe myricetin to play a role of protection for liver damage, And watch the immune enhancement effect on myricetin.
Results confirmed that myricetin can significantly reduce carbon tetrachloride, D2 galactosamine and isothiocyanate naphthalene ester to acute liver injury in mice model, which toxins content in serum, reducing the degeneration and necrosis of liver tissue, and enhance mononuclear macrophage phagocytosis and hemolysin content.
Bayberry extract Illustrates the myricetin has protection of liver, reduction enzyme and retreat yellow, strengthens the nonspecific immune function in mice and immunocompromised mice humoral immune function, thus protecting liver function, provide reference for the clinical application of myricetin.
Bayberry extract widely used in medicine, food, health care products and cosmetics.
Bayberry extract, health care medicine FYI has myricetin as additives which are treatment for the prevention of arthritis and various kinds of inflammation, especially for pregnancy and lactation is more suitable for women and babies.
Bayberry extract with high purity has been widely used in food, medicine and cosmetic fields. ,
As the further study for Bayberry extract of the pharmacological effects, the demand of market of myricetin will increase sharply, The research and development prospect of myricetin are broad.
Bayberry extract is specialty resources in China.
In view of the regional differences, the international on the research of Bayberry extract is just started.
In China now only the research of guangxi rattan tea containing myricetin study more, but zhejiang as big provinces is origin of Bayberry extract.
The research about the active ingredient for special local economic crops is one of the few.
Bayberry extract, the research is relatively backward.
In Ningbo, related companies have begun to development and application of myricetin in preliminary, striving for its industrialization.
Liquid could be used in food additives, such as coarse extraction, separation and purifying of crude extract of active ingredients and pharmacological activity research, etc., and further accelerate the speed of traditional Chinese medicine (TCM) modernization in China.
Bayberry extract is a flavonoid compound found in many fruits and vegetables, including red wine, that acts as a powerful antioxidant.
Bayberry extract inhibits TBARS formation with an IC50 value of 6.34 and at 20 μM, blocks oxLDL uptake by U937-derived macrophages, reducing CD36 expression.
Bayberry extract demonstrates potent chemopreventative potential by binding JAK1/STAT3 to inhibit the neoplastic transformation of murine JB6 P+ cells and inhibiting MEK1 kinase activity.
Bayberry extract exerts anti-oxidant effects, and anti-inflammatory effects by regulating multiple signal pathways.
Bayberry extract also displays anti-diabetic and hepatoprotective effects.
Bayberry extract strongly inhibits yeast α-glucosidase, glyoxalase I in vitro, and bovine milk xanthine oxidase.
It also promotes complex formation between DNA and both topoisomerase I and II, an effect that may have implications in cancer chemotherapy.
Bayberry extract also has various nutraceuticals values and therapeutic effects.
Bayberry extract offers cleansing, astringent and anti-bacterial properties.
Bayberry extract of the botanical Myrica Cerifera Bark in a base of propylene glycol.
It is a slightly viscous brown liquid that is soluble in water.
Melting point: >300 °C(lit.)
Boiling point: 377.41°C (rough estimate)
Density: 1.4222 (rough estimate)
refractive index: 1.4395 (estimate)
storage temp.: 2-8°C
solubility: ethanol: soluble10mg/mL, clear to very faintly turbid, yellow to very deep greenish-yellow
pka: 6.30±0.40(Predicted)
form: crystalline
color: Yellowish Brown
Water Solubility: Soluble in dimethyl sulfoxide,dimethyl formamide and ethanol. Insoluble in water.
LogP: 1.206 (est)
Bayberry extract is a hexahydroxyflavone that is flavone substituted by hydroxy groups at positions 3, 3', 4', 5, 5' and 7.
Bayberry extract has been isolated from the leaves of Myrica rubra and other plants.
It has a role as a cyclooxygenase 1 inhibitor, an antineoplastic agent, an antioxidant, a plant metabolite, a food component, a hypoglycemic agent and a geroprotector.
Bayberry extract is a hexahydroxyflavone and a 7-hydroxyflavonol.
It is a conjugate acid of a myricetin(1-).
Bayberry extract on the study of the resistance drug mechanism of diabetes found that myricetin play a role of hyperglycemia.
Studies use models about diabetes caused by alloxan model, the high sugar lever mice model caused by epinephrine and glucose, as well as the normal mice.
After oral dosing, determination kinds of the model about mice blood sugar levels.
Conclusion has the function of hypoglycemic effect in Alloxan diabetic mice and hyperglycemia mice induced by Adrenalin.
The treatment effect is good, but had no hypoglycemic effect on the normal mice.
Bayberry extract has good fall blood sugar effect for a variety of animal models, and it is expected to develop fall blood sugar medicine.
Mice caused by different factors such as diabetes, as well as the normal small rat poison, the determination of kinds of the model mice’s blood sugar levels.
Result has the function of hypoglycemic effect in Alloxan diabetic mice and hyperglycemia mice induced by Adrenalin, but had no hypoglycemic effect on the normal mice.
In addition, they found in further study, Bayberry extract has good fall blood sugar for a variety of animal models, and it is expected to develop fall blood sugar medicine or as diabetes patients using food additives.
Used to treat gastrointestinal issues like diarrhea and indigestion.
Bayberry extract applied in remedies for coughs, colds, and congestion.
Bayberry extract is used in topical applications for conditions like eczema and psoriasis.
Helps protect the skin from oxidative stress and damage.
May be used to prevent or treat infections due to its antimicrobial properties.
Bayberry extract is used for its astringent properties in various cosmetic and medicinal preparations.
Some individuals may experience allergic reactions, including rashes or itching, especially with topical application.
High doses or improper use might lead to gastrointestinal discomfort, such as nausea or diarrhea.
Limited information is available on the safety of Bayberry extract during pregnancy and breastfeeding.
Bayberry extract’s best to avoid use or consult a healthcare provider.
While not extensively documented, Bayberry extract is advisable to consult a healthcare provider to check for potential interactions with other medications.
The quality of supplements can vary, so it's important to use products from reputable sources to avoid contamination.
Uses:
Bayberry extract is used as an antioxidant.
Bayberry extract is a cell-permeable flavonoid used in inflammatory, diabetes, and cancer studies.
It is effective in protecting neurons against oxidative stresses.
Bayberry extract inhibits yeast alfa-glucosidase,1 glyoxalase I in vitro and bovine milk xanthine oxidase.
Bayberry extract has been evaluated for its anti-inflammatory, antioxidant, and cardiovascular effects, and has demonstrated activity in cancer and diabetes, with most data derived from animal or in vitro studies.
Because clinical data are lacking, bayberry cannot be recommended for any indication.
Traditionally used to treat diarrhea and other gastrointestinal disturbances.
Helps alleviate symptoms of indigestion and stomach discomfort.
Bayberry extract is used to relieve symptoms of coughs and colds.
Helps with nasal and chest congestion.
Bayberry extract applied to tighten and tone tissues, useful in treating wounds and minor skin irritations.
Bayberry extract is used in topical preparations to reduce inflammation and irritation associated with conditions like eczema and psoriasis.
Contains antioxidants that protect the skin from oxidative stress and damage.
May help prevent bacterial infections due to its antibacterial properties.
Bayberry extract is used to treat or prevent fungal infections.
Incorporated into creams and lotions for its skin-tightening properties.
The essential oils extracted from bayberry are used for their aromatic properties in various therapeutic and cosmetic products.
Sometimes used in herbal remedies to help reduce fever and relieve pain.
Bayberry extract is used in traditional practices for its supposed detoxifying effects on the body.
Applied to minor cuts, scrapes, and wounds to promote healing and reduce infection risk due to its astringent and antimicrobial properties.
Sometimes used in oral hygiene products like mouthwashes and toothpaste to help with gum health and reduce inflammation.
Incorporated into anti-aging skin care products for its potential to improve skin elasticity and reduce the appearance of wrinkles.
Traditional uses include alleviating menstrual cramps and other menstrual discomforts, though scientific evidence supporting this use may be limited.
Used in aromatherapy for its relaxing and stress-relieving effects. Essential oils from bayberry may be included in massage oils or diffusers.
Traditionally used to support urinary tract health and alleviate symptoms related to bladder discomfort.
Some traditional practices use bayberry to support overall immune function and increase resistance to illnesses.
Bayberry extract is used to stimulate appetite and aid in the digestion process, especially in cases of loss of appetite.
In some cultures, bayberry is used in folk medicine practices for its believed health benefits and protective properties.
In some traditions, bayberry may be used in religious or ceremonial contexts for its symbolic meanings or as part of ritualistic practices.
Safety Profile:
Bayberry extract contains tannins, which may cause irritation in the gastrointestinal tract when consumed in large amounts.
This can lead to nausea, vomiting, or upset stomach.
Excessive consumption of bayberry extract has been associated with potential liver toxicity due to its high levels of certain compounds that may stress the liver.
Some individuals may experience allergic reactions, such as skin rashes, itching, or swelling after using bayberry extract, particularly in topical applications.
Bayberry may have an effect on blood pressure.
People with high blood pressure or those taking medications for hypertension should use caution, as it could potentially interfere with their treatment.
Bayberry extract is generally not recommended for use during pregnancy or breastfeeding, as it may stimulate uterine contractions, posing risks of miscarriage or complications.
Bayberry extract may interact with certain medications, especially blood thinners or drugs that affect the liver, potentially increasing the risk of adverse effects.
