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BENZOIC ACID PHENYL METHYL ESTER
Benzoic Acid Phenyl Methyl Ester is Character white oily liquid, slightly viscous, pure product is flake crystal.
There is a weak plum, almond aroma.
Benzoic Acid Phenyl Methyl Ester has a slightly pleasant aromatic smell and a burning smell.
CAS Number: 120-51-4
EC Number: 204-402-9
IUPAC Name: benzyl benzoate
Chemical Formula: C14H12O2
Other names: BENZYL BENZOATE, Ascabiol, Benzoic acid, phenylmethyl ester, Benylate, Novoscabin, Benzoic acid benzyl ester, Benzoic acid, benzyl ester, Scabitox, Scobenol, Scabiozon, Ascabin, Benzyl phenylformate, Phenylmethyl benzoate, Benzylets, Colebenz, Peruscabin, Scabagen, Scabanca, benzylbenzoate, Vanzoate, Scabide, Benzyl benzenecarboxylate, Venzonate, Benzylis benzoas, Benzyl alcohol benzoic ester, Benzylester kyseliny benzoove, BENZOIC ACID PHENYLMETHYLESTER, NSC 8081, UNII-N863NB338G, CHEMBL1239, Antiscabiosum, CHEBI:41237, N863NB338G, NSC-8081, NCGC00094981-03, Peruscabina, DSSTox_CID_9153, Benzylum benzoicum, DSSTox_RID_78686, DSSTox_GSID_29153, Benzoesaeurebenzylester, Caswell No. 082, Benzylbenzenecarboxylate, Venzoate, FEMA Number 2138, Benzyl benzoate, analytical standard, Benzyl benzoate (natural), BZM, SMR000471875, HSDB 208, EPA Pesticide Chemical Code 009501, benzylbenzoat, BRN 2049280, Acarobenzyl, Benzevan, Bengal, benzyl-benzoate, AI3-00523, 1dzm, Benylate (TN), benzoic acid benzyl, Spectrum_001240, Benzoic acid-benzyl ester, Spectrum2_000532, Spectrum3_001757, Spectrum4_000773, Spectrum5_001128, WLN: RVO1R, Benzyl benzoate, >=99%, SCHEMBL3038, BENZYL BENZOATE BP98, BSPBio_003494, KBioGR_001186, KBioSS_001720, MLS001066412, MLS001336003, MLS001336004, DivK1c_000204, SPECTRUM1503002, SPBio_000543, Benzyl benzoate (JP17/USP), ZINC1021, DTXSID8029153, BENZOIC ACID,BENZYL ESTER, HMS500K06, KBio1_000204, KBio2_001720, KBio2_004288, KBio2_006856, KBio3_002714, NSC8081, NINDS_000204, HMS1921P16, HMS2092F20, HMS2269D24, Pharmakon1600-01503002, HY-B0935, Tox21_111372, Tox21_201337, Tox21_303418, BDBM50134035, CCG-39578, NSC758204, s4599, STL183088, AKOS003495939, Benzyl benzoate, >=99%, FCC, FG, Tox21_111372_1, DB00676, NSC-758204, IDI1_000204, Benzyl benzoate, for synthesis, 99.0%, NCGC00094981-01, NCGC00094981-02, NCGC00094981-04, NCGC00094981-05, NCGC00094981-07, NCGC00257502-01, NCGC00258889-01, AC-17033, LS-14279, SBI-0051748.P002, DB-041563, B0064, FT-0622708, Benzyl benzoate, natural, >=99%, FCC, FG, Benzyl benzoate, ReagentPlus(R), >=99.0%, Benzyl benzoate, SAJ first grade, >=98.0%, Benzyl benzoate, tested according to Ph.Eur., A14577, A19449, Benzyl benzoate, SAJ special grade, >=99.0%, D01138, AB00052298_07, Benzyl benzoate, Vetec(TM) reagent grade, 98%, Benzyl benzoate, meets USP testing specifications, Q413755, SR-01000763773, Benzoic acid-benzyl ester 5000 microg/mL in Hexane, Q-200696, SR-01000763773-2, BRD-K52072429-001-06-1, Benzoic acid-benzyl ester 100 microg/mL in Acetonitrile, Benzoic acid benzyl ester, Benzoic acid phenylmethyl ester, Benzoic acid benzyl ester, Ascabin, Ascabiol, Benylate, Benzyl alcohol benzoic ester, BENZOATO DE BENCILO, Benzoic acid phenylmethyl ester, Benzyl benzene carboxylate, Benzyl phenylformate, Phenylmethyl benzoate, Scabagen, Vanzoate, Benzyl benzoate BP
Benzoic Acid Phenyl Methyl Ester can volatilize with water vapor.
Benzoic Acid Phenyl Methyl Ester is miscible with alcohol, chloroform, ether and oil, and insoluble in water or glycerin.
Benzoic Acid Phenyl Methyl Ester is a natural product found in Lonicera japonica, Populus tremula, and other organisms with data available.
Benzoic Acid Phenyl Methyl Ester is Soluble in ethanol, ether, chloroform and oil, almost insoluble in water and glycerol.
Benzoic Acid Phenyl Methyl Ester was first studied medically in 1918.
Benzoic Acid Phenyl Methyl Ester is on the World Health Organization's List of Essential Medicines.
Benzoic Acid Phenyl Methyl Ester is an organic compound with the formula C6H5CH2O2CC6H5.
Benzoic Acid Phenyl Methyl Ester is the ester of benzyl alcohol and benzoic acid.
Benzoic Acid Phenyl Methyl Ester forms either a viscous liquid or solid flakes and has a weak, sweet-balsamic odor.
Benzoic Acid Phenyl Methyl Ester, a white, crystalline organic compound, is a family carboxylic acids.
Benzoic Acid Phenyl Methyl Ester occurs in a number of blossoms (e. g. tuberose, hyacinth) and is a component of Balsam of Peru and Tolu balsam.
Though Benzoic Acid Phenyl Methyl Ester occurs naturally in some plants, Benzoic Acid Phenyl Methyl Ester is commercially manufactured by the reaction of toluene with oxygen at temperatures around 200 C in the presence of cobalt and manganese salts as catalysts.
Benzoic Acid Phenyl Methyl Ester has a carboxyl group bound directly to a benzene ring.
Pure Benzoic Acid Phenyl Methyl Ester melts at 122 C and is very slightly soluble in water.
Benzoic Acid Phenyl Methyl Ester is an aromatic substance with good dehydrating and alcohol detracting capacities.
Benzoic Acid Phenyl Methyl Ester is one of the popular food additives and ingredients in most countries.
Benzoic Acid Phenyl Methyl Ester is a naturally occurring molecule found in some plants and is made up of benzyl alcohol and benzoic acid.
Benzoic Acid Phenyl Methyl Ester is registered under the REACH Regulation and is manufactured in and / or imported to the European Economic Area, at ≥ 1 000 tonnes per annum.
Benzoic Acid Phenyl Methyl Ester is used by consumers, by professional workers (widespread uses), in formulation or re-packing, at industrial sites and in manufacturing.
Benzoic Acid Phenyl Methyl Ester is the drug (pharma grade) type.
Benzoic Acid Phenyl Methyl Ester is an aromatic chemical, usually appearing as a clear liquid with a mild sweet-balsamic fragrance.
Benzoic Acid Phenyl Methyl Ester appears as a component of some of our fragrance blends.
Benzoic Acid Phenyl Methyl Ester is a synthetic chemical produced for industry from benzyl alcohol and benzoic acid, but is also naturally present in the essential oils of many plants, including cinnamon, balsam of peru and ylang ylang.
Benzoic Acid Phenyl Methyl Ester is a very important organic compound which has a faint aromatic odour.
Benzoic Acid Phenyl Methyl Ester is the ester of Benzyl Alcohol and Benzoic Acid.
Benzoic Acid Phenyl Methyl Ester is a non-toxic, colorless, liquid compound that has a variety of uses that include the manufacture of cellulose and other polymers for commercial applications.
However at temperatures below 17 ºC, Benzoic Acid Phenyl Methyl Ester is a solid, therefore heated storage would be required.
Benzoic Acid Phenyl Methyl Ester, is the ester of benzyl alcohol and benzoic acid, with the formula C6G5CH2O2CC6H5.
This easily prepared compound has a variety of uses.
Benzoic Acid Phenyl Methyl Ester is a colorless liquid, that is formally the condensation product of benzoic acid and benzyl alcohol.
However Benzoic Acid Phenyl Methyl Ester is a solid at temperatures below 17 ºC so insulated storage would be required.
USES and APPLICATIONS of BENZOIC ACID PHENYL METHYL ESTER:
-Cosmetic Uses of Benzoic Acid Phenyl Methyl Ester:
*antimicrobial agents
*perfuming agents
*solvents
-Benzoic Acid Phenyl Methyl Ester is an organic compound which is used as a medication and insect repellent.
-As a medication Benzoic Acid Phenyl Methyl Ester is used to treat scabies and lice.
-For scabies either permethrin or malathion is typically preferred.
-Benzoic Acid Phenyl Methyl Ester is applied to the skin as a lotion.
Typically two to three applications are needed.
-Benzoic Acid Phenyl Methyl Ester is also present in Balsam of Peru, Tolu balsam, and in a number of flowers.
-Medical:
Benzoic Acid Phenyl Methyl Ester is an effective and inexpensive topical treatment for human scabies.
Benzoic Acid Phenyl Methyl Ester has vasodilating and spasmolytic effects and is present in many asthma and whooping cough drugs.
Benzoic Acid Phenyl Methyl Ester is also used as an excipient in some testosterone-replacement medications (like Nebido) for treating hypogonadism.
-Benzoic Acid Phenyl Methyl Ester is used as a topical acaricide, scabicide, and pediculicide in veterinary hospitals.
-Non-medical:
Benzoic Acid Phenyl Methyl Ester is used as a repellent for chiggers, ticks, and mosquitoes.
-Benzoic Acid Phenyl Methyl Ester is also used as a dye carrier, solvent for cellulose derivatives, plasticizer, and fixative in the perfume industry.
-Benzoic Acid Phenyl Methyl Ester is one of the older preparations used to treat scabies.
Scabies is a skin infection caused by the mite sarcoptes scabiei.
Benzoic Acid Phenyl Methyl Ester is characterised by severe itching (particularly at night), red spots, and may lead to a secondary infection.
Benzoic Acid Phenyl Methyl Ester is lethal to this mite and so is useful in the treatment of scabies.
-Benzoic Acid Phenyl Methyl Ester is also used to treat lice infestation of the head and body.
-Benzoic Acid Phenyl Methyl Ester is used for fixative of solvent and essence of Musk, substitute of camphor, also used for preparation of pertussis medicine, asthma medicine, etc colorless oily liquid with weak Balsam and almond fragrance.
-Benzoic Acid Phenyl Methyl Ester mainly used as fixative.
-For the preparation of strawberry, pineapple, cherry and other fruit food flavor and wine flavor, but also for Jasmine, lily of the valley, ylang ylang, gardenia, Terminus, clove and other daily flavor.
-The amount of gum used was 280mg/kg; 39mg/kg in candy; 33mg/kg in baked food; 45mg/kg in soft drinks; 12mg/kg in cold drinks.
-Benzoic Acid Phenyl Methyl Ester is mainly used in textile auxiliaries, flavors and fragrances, plasticizers and other fields, and has excellent plasticizing
properties.
-Benzoic Acid Phenyl Methyl Ester Indication:
Benzoic Acid Phenyl Methyl Ester is used to kill lice and the mites responsible for the skin condition scabies.
-Benzoic Acid Phenyl Methyl Ester is used mainly as a non-agricultural pesticide although Benzoic Acid Phenyl Methyl Ester also has other manufacuring application.
Benzoic Acid Phenyl Methyl Ester has a low aqueous solubility and is moderately volatile.
-Benzoic Acid Phenyl Methyl Ester is used for the synthesis of drugs (especially for antispasmodic drugs as a scabicides and to treat pediculosis).
-Benzoic Acid Phenyl Methyl Ester finds application in fragrance.
-Benzoic Acid Phenyl Methyl Ester is used in pre-fixing agent.
-Benzoic Acid Phenyl Methyl Ester itself is not an active fragrance ingredient.
Benzoic Acid Phenyl Methyl Ester improves the stability and odor characteristics of the main ingredients.
-Benzoic Acid Phenyl Methyl Ester is used as a miticide and in food field.
-Benzoic Acid Phenyl Methyl Ester is also used as a plasticizer for polymers and cellulose.
-Benzoic Acid Phenyl Methyl Ester is widely used as a food preservative, normally as the sodium, potassium, or calcium salts and their derivatives especially in acid foods.
-Benzoate preservatives applications in foods, drugs and personal products are well established.
-Benzoic Acid Phenyl Methyl Ester is also widely as an intermediate for chemicals, alkyd resins, polyesters, plasticizers, dyestuffs, preservatives, and rubber activators and retardants.
-Benzoic Acid Phenyl Methyl Ester is a diverting agent in crude oil recovery applications.
-Generally Benzoic Acid Phenyl Methyl Ester is used for paraffin embedding.
-After dehydration by increasing alcohol concentrations the sample is cleared by Benzoic Acid Phenyl Methyl Ester and then embedded in paraffin.
-In cosmetic products, Benzoic Acid Phenyl Methyl Ester plays a number of roles depending on the product and Benzoic Acid Phenyl Methyl Ester can act as a fragrance, a solvent, a plasticiser, a preservative and a fixative.
-Benzoic Acid Phenyl Methyl Ester is used to a preferred treatment for scabies and lice.
-Benzoic Acid Phenyl Methyl Ester also works as an insect repellent against bugs like mosquitoes and ticks.
-Benzoic Acid Phenyl Methyl Ester is an acaricide used in the treatment of scabies.
-Benzyl Benzoate has seen use as an insecticide, as well as a solvent for various chemical reactions.
-Benzoic Acid Phenyl Methyl Ester is used to treat lice and scabies infestations.
Benzoic Acid Phenyl Methyl Ester is believed to be absorbed by the lice and mites and to destroy them by acting on their nervous system.
-Benzoic Acid Phenyl Methyl Ester is one of the older preparations used to treat scabies. Scabies is a skin infection caused by the mite sarcoptes scabiei.
Benzoic Acid Phenyl Methyl Ester is characterised by severe itching (particularly at night), red spots, and may lead to a secondary infection.
Benzoic Acid Phenyl Methyl Ester is lethal to this mite and so is useful in the treatment of scabies.
-Benzoic Acid Phenyl Methyl Ester is also used to treat lice infestation of the head and body.
-Benzoic Acid Phenyl Methyl Ester is an antiparasitic medicines.
Benzoic Acid Phenyl Methyl Ester works by killing the tiny insects (mites) and their eggs, which cause scabies.
-Benzoic Acid Phenyl Methyl Ester Applications:
*Plastic plasticizer.
*Incense agent.
*A solvent used as a cellulose acetate and a nitric acid fiber.
*Benzoic Acid Phenyl Methyl Ester is widely used in the daily flavoring formula, mainly used as a filling agent, and often used as a diluent for many high viscous synthetic fragrances.
-Consumer Uses:
Benzoic Acid Phenyl Methyl Ester is used in the following products: washing & cleaning products, air care products, polishes and waxes, perfumes and fragrances and cosmetics and personal care products.
-Benzoic Acid Phenyl Methyl Ester is used in the removal of skin infections.
-Other release to the environment of Benzoic Acid Phenyl Methyl Ester is likely to occur from: indoor use as processing aid and outdoor use as processing aid.
-Benzoic Acid Phenyl Methyl Ester often appears in fragrances, either as a synthetic additive used as a fixative to help preserve the longevity of a fragrance, or as a natural component of the essential oils used in the fragrance.
-Benzoic Acid Phenyl Methyl Ester is also used in medicine for the topical treatment of some skin conditions.
-Benzoic Acid Phenyl Methyl Ester is used in the creation of the oldest formulas used for the treatment of a skin disease called scabies.
This is a skin infection.
-Benzoic Acid Phenyl Methyl Ester is an ingredient used in the manufacture of drugs produced to inhibit ticks and mosquitoes.
-Benzoic Acid Phenyl Methyl Ester is a chemical substance used as a solvent in many various chemicals.
-Benzoic Acid Phenyl Methyl Ester is used as a solvent of cellulose materials.
-Benzoic Acid Phenyl Methyl Ester is used as an essence in perfume production.
-Benzoic Acid Phenyl Methyl Ester is used in the production of veterinary drugs, in chemicals produced for the treatment of skin diseases of animals.
-Benzoic Acid Phenyl Methyl Ester is used as a sweetener in the Food Industry.
-Benzoic Acid Phenyl Methyl Ester is used in the manufacture of insecticides for some textiles, carpets, mattresses and sofa upholstery, and for the treatment of dust setting in furniture.
-Benzoic Acid Phenyl Methyl Ester is used as an important compound for preparing topical ointments.
-Benzoic Acid Phenyl Methyl Ester is also used as a dye carrier, solvent for cellulose derivatives, plasticizer and a fixative in the perfume industry.
-Benzoic Acid Phenyl Methyl Ester has vasodilating and spasmolytic effects and is present in many asthma and whooping cough drugs.
-Benzoic Acid Phenyl Methyl Ester is also a dye carrier, solvent for cellulose derivatives, plasticizer, and fixative in the perfume industry
-Benzoic Acid Phenyl Methyl Ester, is a non-phthalate plasticizer.
-Benzoic Acid Phenyl Methyl Ester is primarily used as a plasticizer in the plastics industry for the manufacture of a wide variety of products used in everyday life.
-Benzoic Acid Phenyl Methyl Ester is used to make synthetic rubber, Bakelite, neoprene, nylon, PVC, polystyrene, polyethylene, polypropylene, silicone and many more.
-Benzoic Acid Phenyl Methyl Ester’s for external use.
-Benzoic Acid Phenyl Methyl Ester is an effective and inexpensive topical treatment for human scabies.
-Benzoic Acid Phenyl Methyl Ester is primarily used as a plasticizer in the manufacture of polymeric materials for commercial applications such as PVC and other plastics.
-Benzoic Acid Phenyl Methyl Ester is used as repellent for chiggers, ticks, and mosquitoes.
-However, Benzoic Acid Phenyl Methyl Ester is also used as a fixative in fragrances, a food additive in artificial flavors, as a solvent, and for a variety of medical applications for the health care industry and veterinarians.
MECHANISM of ACTION of BENZOIC ACID PHENYL METHYL ESTER:
Benzoic Acid Phenyl Methyl Ester exerts toxic effects on the nervous system of the parasite, resulting in its death.
Benzoic Acid Phenyl Methyl Ester is also toxic to mite ova, though Benzoic Acid Phenyl Methyl Ester's exact mechanism of action is unknown.
In vitro, Benzoic Acid Phenyl Methyl Ester has been found to kill the Sarcoptes mite within 5 minutes.
ABSORPTION of BENZOIC ACID PHENYL METHYL ESTER:
No data are available on percutaneous absorption of benzyl benzoate.
Some older studies have suggested some percutaneous absorption, however the amount was not quantified.
PRODUCTION of BENZOIC ACID PHENYL METHYL ESTER:
Benzoic Acid Phenyl Methyl Ester is produced industrially by the reaction of sodium benzoate with benzyl chloride in the presence of a base, or by transesterification of methyl benzoate and benzyl alcohol.
Benzoic Acid Phenyl Methyl Ester is a byproduct of benzoic acid synthesis by toluene oxidation.
Benzoic Acid Phenyl Methyl Ester can also be synthesized by the Tishchenko reaction, using benzaldehyde with sodium benzyloxide (generated from sodium and benzyl alcohol) as catalyst.
Benzoic Acid Phenyl Methyl Ester is a benzoate ester obtained by the formal condensation of benzoic acid with benzyl alcohol.
Benzoic Acid Phenyl Methyl EsterIt has been isolated from the plant species of the genus Polyalthia.
Benzoic Acid Phenyl Methyl Ester has a role as a scabicide, an acaricide and a plant metabolite.
Benzoic Acid Phenyl Methyl Ester is a benzyl ester and a benzoate ester.
Benzoic Acid Phenyl Methyl Ester is functionally related to a benzoic acid.
PREPARATION METHOD of BENZOIC ACID PHENYL METHYL ESTER:
Benzoic Acid Phenyl Methyl Ester was obtained by transesterification of ethyl benzoate with benzyl alcohol, washed with water, layered, dried and distilled.
Alternatively, Benzoic Acid Phenyl Methyl Ester is prepared by condensation of benzaldehyde.
HOW DOES BENZOIC ACID PHENYL METHYL ESTER WORK?
As a fragrance, Benzoic Acid Phenyl Methyl Ester can add a balsamic smell to a product.
Benzoic Acid Phenyl Methyl Ester can also work with other fragrances as a solvent to help them dissolve into the mixture.
Benzoic Acid Phenyl Methyl Ester also acts as a fixative in perfumed products where Benzoic Acid Phenyl Methyl Ester slows down the escape of other fragrances and increases the life span of the fragrance.
When added to more solid products like soaps, Benzoic Acid Phenyl Methyl Ester can act as a plasticiser.
A plasticiser makes a product less brittle so a soap containing Benzoic Acid Phenyl Methyl Ester can be bent and squished more before it snaps or crumbles.
