PRODUCTS

BENZOPHENONE-2

BENZOPHENONE-2 = 2,2',4,4'-tetrahydroxybenzophenone

CAS No.: 131-55-5
EC No.: 205-028-9
Linear Formula: [(HO)2C6H3]2CO / C13H10O5

Benzophenone-2 is a light yellow crystalline powder made from 2-hydroxybenzophenone.
Ultraviolet absorber Benzophenone-2 is a benzophenone ultraviolet absorber, the absorption wavelength range is 320-400nm, Benzophenone-2 has a symmetrical benzene ring and hydroxyl groups on both sides, and Benzophenone-2's thermophotochemical properties are stable.

Benzophenone-2 is water-insoluble, dissolved in methanol and ethanol, capable of absorbing the UV radiation of 320-400nm wavelength with the characteristics of light color, nontoxic, good compatibility.

Stability of light, heat chemical is better then Benzophenone-3(UV-9).
Benzophenone-2 is a light yellow crystalline powder made from 2-hydroxybenzophenone.
Benzophenone-2, -6 and -8 are compounds made from 2-hydroxybenzophenone.

Benzophenone is a substance that acts as a sunscreen and absorber of ultraviolet radiation to protect products from UV rays.
Its derivatives are benzophenone-2 (BP2) and oxybenzone (benzophenone-3 or BP3).

USES and APPLICATIONS of BENZOPHENONE-2:
-Benzophenone-2 is classified as :
Masking
Uv absorber

-Cosmetic Uses:
fragrance
uv Benzophenone-2 is suitable for polyester, coatings and cosmetics, etc.

-In recent years, Benzophenone-2's application in fabrics has been valued by the textile industry, and Benzophenone-2's scope has become wider and wider.
-Hair care (Shampoos, Conditioners & Styling)

-Perfumes & fragrances
-Skin care (Facial care, Facial cleansing, Body care, Baby care)
-Sun care (Sun protection, After-sun & Self-tanning) absorption

-Benzophenone-2 is used as a UV absorber in the formulation of aftershave lotion, bath products, bubble baths, colognes, perfumes, eye makeup removers, and other skin and hair care products to protect cosmetics and personal care products from deterioration by absorbing, reflecting, or scattering UV rays.

-Masking agent:
Reduces or inhibits the base odor or taste of the product.

-Stabilizing Agent:
Improves ingredients or formulation stability and shelf life.

-UV absorber:
Protects the cosmetic product against the effects of UV light.

-Benzophenone-2 is used in personal care products such as lip balm and nail polish to protect the products from UV light.
-Derivatives of benzophenone, such as benzophenone-2 (BP2) and oxybenzone (benzophenone-3 or BP3) are common ingredients in sunscreen.

-Found in:
Lip balm, nail polish, foundations, baby sunscreens, fragrance, shampoo, conditioner, hair spray, moisturizers, and foundation
-Benzophenone-2 is widely used in household products, such as sunglasses, food packaging, laundry and cleaning products to protect from UV light.

-Benzophenone-2 occurs naturally in some foods (such as wine grapes and muscat grapes) and is added to other foods as a flavoring.
-In personal care products, Benzophenone-2 is used as a fragrance enhancer or to prevent products such as soaps from losing scents and colors in the presence of UV light.

-Derivatives of benzophenones such as BP2 and oxybenzone (BP3) are used in sunscreens.
-Benzophenone-2 and oxybenzone are also used in nail polish, and lip balm.

-Benzophenone-2 is a chemical ingredient used in sunscreen and personal care products to provide sunprotection by filtering ultraviolet light.
-Benzophenone-2 is used in the manufacture of antihistamines, hypnotics, insecticides.
-Benzophenone-2 is used as a synthetic intermediate in the manufacture of pharmaceuticals and agricultural chemicals.

-Benzophenone-2 is also used as a photoinitiator in UV-curable printing inks, as a fragrance in perfumes, and as a flavor enhancer in foods.
-Benzophenone-2 is found lip glosses, nail polishes, foundations, children's sunscreens, fragrances, shampoo, conditioners, hairspray, moisturizers.
-Benzophenone-2 is one of the most commonly used photosensitizers in photochemistry.

-Benzophenone-2 are also considered chemical light protection filters.
However, they work on a hormone-activating basis.

-In cosmetics and personal care products, Benzophenone-2 is used in the formulation of aftershave lotion, bath products, bubble baths, colognes, perfumes, eye makeup removers, and other skin and hair care products.

-Benzophenones absorb and dissipate UV radiation, which serves to protect cosmetics and personal care products.
As part of sunscreen products, which are OTC drugs in the United States, Benzophenone-8 (Dioxybenzone) protects the skin from the harmful effects of the sun.

-Benzophenone-2, -6 and -8 protect cosmetics and personal care products from deterioration by absorbing, reflecting, or scattering UV rays.
-Benzophenone-2 is used in the formulation of aftershave lotion, bath products, bubble baths, colognes, perfumes, eye makeup removers, and other skin and hair care products.

-Benzophenone-2 absorb and dissipate UV radiation, which serves to protect cosmetics and personal care products.
-Benzophenone-2 is an effective light stabilizer for protecting plastics, coatings and cosmetics from the damaging UV radiation which is a component of natural sunlight.

-Benzophenone-2 is very compatible with plastic optical lens materials and is extremely useful as a UV screen in these products.
-In cosmetics/perfumes, the stability is improved.
-Benzophenone-2 stabilizes colors in various applications.

-Benzophenone-2 has a very broad absorption band which extends into the UV-A range.
-Benzophenone-2 is used as a UV absorber in the formulation of aftershave lotion, bath products, bubble baths, colognes, perfumes, eye makeup removers, and other skin and hair care products to protect cosmetics and personal care products from deterioration by absorbing, reflecting, or scattering UV rays.

-Benzophenone-2 is also frequently used to improve the stability of perfumes to oxidation.
-Occurrence in other products:
As a photoinitiator in UV curing applications (such as inks and coatings in the printing industry)

-Benzophenone-2 is a UV-A filter.
Benzophenone-2 protects colorants against fading.
Benzophenone-2 improves the stability of fragrances to oxidation.

-Occurrence in cosmetics:
As a UV absorber to protect z. B. fragrances, dyes and light-sensitive active ingredients in products such as perfumes and soaps as well as to protect plastic packaging from UV radiation

-Benzophenone-2 is widely applied to PE, PVC, PP, PC, solar films, stickers, high-end cosmetics, the new high-grade paint and paint.
-Application Because of Benzophenone-2's wide absorption range, Benzophenone-2 is particularly suitable for use as a UV-A filter for product protection, particularly to protect colorants against fading.

-Benzophenone-2 is also frequently used to improve the stability of perfumes to oxidation.
-UV absorber: protects the cosmetic product from the effects of UV light.
-Benzophenone-2 is used as a pharmaceutical intermediate, photosensitive material, cosmetic UV protection additive, etc.

FUNCTION(S) of BENZOPHENONE-2 IN COSMETIC PRODUCTS:
-LIGHT PROTECTION:
Protects the cosmetic product from damage caused by light.

-PERFUMED:
Improves the smell of a product and/or perfumes the skin.

-UV ABSORBER:
Protects the cosmetic from damage caused by UV light.

-UV RAY ABSORBER
Protects the cosmetic product from the effects of UV light.

-MASK
Reduces or inhibits base product odor or flavor.

RELATED INGREDIENTS of BENZOPHENONE-2:
-Benzophenone-1
-Benzophenone-3 (Oxybenzone)
-Benzophenone-4
-Benzophenone-5
-Benzophenone-9
-Benzophenone‐1
-Dioxybenzone
-Sunscreen Without Chemical Blocker

PHYSICAL and CHEMICAL PROPERTIES of BENZOPHENONE-2:
Molecular Weight: 246.22
Appearance Form: solid
Odor: No data available
Odor Threshold: No data available
pH: No data available
Melting point/freezing point:
Melting point/range: 198 - 200 °C - lit.
Initial boiling point and boiling range: No data available
Flash point: Not applicable

Evaporation rate: No data available
Flammability (solid, gas): No data available
Upper/lower flammability or explosive limits: No data available
Vapor pressure: No data available
Vapor density: No data available
Density: No data available
Relative density: No data available

Water solubility: No data available
Partition coefficient: n-octanol/water: No data available
Autoignition temperature: No data available
Decomposition temperature: No data available
Viscosity
Viscosity, kinematic: No data available
Viscosity, dynamic: No data available

Explosive properties: No data available
Oxidizing properties: No data available
Other safety information: No data available
Appearance: Light yellow powder Content: ≥99%
Melting point: ≥195°C
Moisture: ≤1%
Chroma: ≤4

Assay: 95.00 to 100.00
Food Chemicals Codex Listed: No
Boiling Point: 531.23 °C. @ 760.00 mm Hg (est)
Flash Point: 552.00 °F. TCC ( 289.10 °C. ) (est)
logP (o/w): 3.091 (est)
Soluble in: water, 398.5 mg/L @ 25 °C (est)

Molecular Weight: 246.21
XLogP3-AA: 2.4
Hydrogen Bond Donor Count: 4
Hydrogen Bond Acceptor Count:5
Rotatable Bond Count: 2
Exact Mass: 246.05282342
Monoisotopic Mass: 246.05282342
Topological Polar Surface Area: 98 Å²

Heavy Atom Count: 18
Formal Charge: 0
Complexity: 278
Appearance: Light yellow crystal
Assay: ≥ 99.0%
Melting point: ≥195℃
Loss on drying: 0.5% max
Lovibond color: ≤3.0
Heavy metal: ≤5ppm

Specific Extinction: 580
Turbidity: 12NTU
Appearance: Pale greenish yellow crystalline powder
Purity (HPLC): 99.0% min
Solubility: Clear solution, free from insoluble
Melting Point: 195.0℃～203.0℃
Gardner Color: 3.0 max
Specific Extinction (1%,1cm) E345: 580 min

Loss on Drying: 0.5% max
Turbidity: 12NTU max
Appearance: Pale greenish yellow crystalline powder
Solubility: Clear solution, free from insoluble
Assay: ≥99%
Melting point: 195.0~203.0 deg. c.
Gardner color: ≤3.0
Heat Loss: ≤0.5%
Specific Extinction E345(1%,1cm): ≥580
Turbidity: 12NTU max

FIRST AID MEASURES of BENZOPHENONE-2:
-Description of first-aid measures:
*General advice:
Show this material safety data sheet to the doctor in attendance.

*If inhaled
After inhalation:
Fresh air.

*In case of skin contact:
Take off immediately all contaminated clothing.
Rinse skin with water/ shower.
Consult a physician.

*In case of eye contact:
After eye contact:
Rinse out with plenty of water.
Call in ophthalmologist.
Remove contact lenses.

*If swallowed:
After swallowing:
Immediately make victim drink water (two glasses at most).
Consult a physician.

-Indication of any immediate medical attention and special treatment needed:
No data available

ACCIDENTAL RELEASE MEASURES of BENZOPHENONE-2:
-Environmental precautions:
Do not let product enter drains.

-Methods and materials for containment and cleaning up:
Cover drains.
Collect, bind, and pump off spills.
Take up dry.
Dispose of properly.

FIRE FIGHTING MEASURES of BENZOPHENONE-2:
-Extinguishing media:
*Suitable extinguishing media:
Use extinguishing measures that are appropriate to local circumstances and the surrounding environment.

*Unsuitable extinguishing media:
For this substance/mixture no limitations of extinguishing agents are given.

-Special hazards arising from the substance or mixture:
Nature of decomposition products not known.
Not combustible.

EXPOSURE CONTROLS/PERSONAL PROTECTION of BENZOPHENONE-2:
-Control parameters:
--Ingredients with workplace control parameters:
-Exposure controls:
--Personal protective equipment:

*Eye/face protection:
Use safety glasses.

*Skin protection:
Full contact:
Material: Nitrile rubber
Minimum layer thickness: 0,11 mm
Break through time: 480 min

Splash contact:
Material: Nitrile rubber
Minimum layer thickness: 0,11 mm
Break through time: 480 min

*Body Protection:
Protective clothing.

-Control of environmental exposure
Do not let product enter drains.

HANDLING and STORAGE of BENZOPHENONE-2:
-Conditions for safe storage, including any incompatibilities:
*Storage conditions:
Tightly closed.
Dry.

STABILITY and REACTIVITY of BENZOPHENONE-2:
-Reactivity:
No data available

-Chemical stability:
The product is chemically stable under standard ambient conditions (room temperature) .

-Possibility of hazardous reactions:
No data available

-Conditions to avoid:
No information available

SYNONYMS:
Bis-(2,4-Dihydroxy-Phenyl)-Methanone
UV Absorber BP-2
UV Absorber UVBP-2
Light Stabilizer BP-2
2,2,4,4-Tetrahydroxybenzophenone
2,2,4,4-Tetrehydroxybenzophenone
Di(2,4-dihydroxyphenyl)methanone
Bis(2,4-dihydroxyphenyl)methanone
Benzophenone-2
Ultraviolet Absorber BP-2
UVBP-2
BP-2
2,2',4,4'-Tetrahydroxybenzophenone
Bis(2,4-dihydroxyphenyl)methanone
Benzophenone-2
Methanone, bis(2,4-dihydroxyphenyl)-
Uvinol D-50
Uvinul D-50
2,2',4,4'-Tetrehydroxybenzophenone
UNII-PRR8K3H9VN
NSC 38556
2,2',4,4'-Tetrahydroxy-benzophenone
BENZOPHENONE, 2,2',4,4'-TETRAHYDROXY-
MFCD00002278
PRR8K3H9VN
DSSTox_CID_21306
DSSTox_RID_79684
DSSTox_GSID_41306
2,2',4,4'-hydroxybenophenone
BRN 1914746
di2,4-dihydroxyphenyl ketone
benzophenone 2
4mgc
27M
ST055642
UVINUL D50
Polyhydroxy benzophenone, 4
Oprea1_250768
SCHEMBL39507
2,4'-Tetrahydroxybenzophenone
BIDD:ER0038
Methanone,4-dihydroxyphenyl)-
CHEMBL3185091
DTXSID5041306
HSDB 8386
ZINC39103
2,4,4'-Tetrahydroxybenzophenone
2,2',4'-Tetrahydroxybenzophenone
BDBM234390
AMY22831
BCP25884
NSC38556
Tox21_202288
Tox21_303639
BBL012188
NSC-38556
STK803083
Benzophenone,2',4,4'-tetrahydroxy-
2, 2',4,4'-tetrahydroxybenzophenone
2,2',4,4'-tetrahydroxy benzophenone
AKOS002319293
MCULE-4186572897
2,2',4,4'-Tetrahydroxybenzophenone
NCGC00249205-01
NCGC00249205-02
NCGC00257395-01
NCGC00259837-01
2,2',4,4'-Tetrahydroxy diphenyl ketone
AC-10378
AS-13615
I955
SY020047
DB-042043
2,2',4,4'-Tetrahydroxybenzophenone, 97%
CS-0089098
FT-0609099
T0118
H10707
A806282
SR-01000199334
SR-01000199334-1
W-108329
Q27286728
2,2 inverted exclamation mark ,4,4 inverted exclamation mark -Tetrahydroxybenzophenone
2,2', 4,4'-TETRAHYDROXYBENZOPHENONE
BIS (2,4-DIHYDROXYPHENYL) METHANONE
PHENYL KETONE
BENZOYLBENZENE
BENZOPHENONE
DIPHENYL KETONE
DIPHENYLMTHANONE
BENZOPHENONE 2