PRODUCTS

BENZYL BENZOATE

Benzyl Benzoate is a mediation and insect repellent.
Benzyl Benzoate is one of the older preparation used to treat scabies which is a skin infections caused by the mite scarcoptes scabiei since it is lethal to the mite.
Benzyl Benzoate can also be used for the treatment of lice infestation of the head and the body.

CAS Number: 120-51-4
Molecular Formula: C14H12O2
Molecular Weight: 212.24
EINECS Number: 204-402-9

Synonyms: BENZYL BENZOATE, 120-51-4, Ascabiol, Benylate, Benzoic acid, phenylmethyl ester, Benzoic acid benzyl ester, Scabiozon, Benzoic acid, benzyl ester, Novoscabin, Scabitox, Scobenol, Phenylmethyl benzoate, Ascabin, Scabagen, Benzyl phenylformate, Benzylets, Colebenz, Peruscabin, Scabanca, Scabide, Vanzoate, Benzyl benzenecarboxylate, benzylbenzoate, Antiscabiosum, Venzonate, Benzylis benzoas, Peruscabina, Benzylbenzenecarboxylate, Benzyl alcohol benzoic ester, Benzylum benzoicum, BENZYL-D5 BENZOATE, Benzoesaeurebenzylester, FEMA Number 2138, Benzyl benzoate (natural), Benzylester kyseliny benzoove, NSC 8081, BENZOIC ACID PHENYLMETHYLESTER, Acarobenzyl, FEMA No. 2138, Benzevan, HSDB 208, NSC-8081, EINECS 204-402-9, EPA Pesticide Chemical Code 009501, UNII-N863NB338G, BRN 2049280, 347840-01-1, DTXSID8029153, CHEBI:41237, AI3-00523, N863NB338G, MFCD00003075, Benzyl benzoate [USP], CHEMBL1239, BENZYLOXY PHENYL KETONE, DTXCID809153, EC 204-402-9, 4-09-00-00307 (Beilstein Handbook Reference), NCGC00094981-03, Benzyl benzoate (USP), BENZYL BENZOATE (II), BENZYL BENZOATE [II], BENZYL BENZOATE (MART.), BENZYL BENZOATE [MART.], Caswell No. 082, BENZYL BENZOATE (USP-RS), BENZYL BENZOATE [USP-RS], Acarosan, Venzoate, Benzyl benzoate, analytical standard, BENZYL BENZOATE (EP IMPURITY), BENZYL BENZOATE [EP IMPURITY], BENZYL BENZOATE (EP MONOGRAPH), BENZYL BENZOATE (USP IMPURITY), BENZYL BENZOATE [EP MONOGRAPH], BENZYL BENZOATE [USP IMPURITY], BENZYL BENZOATE (USP MONOGRAPH), BENZYL BENZOATE [USP MONOGRAPH], Benzoate de benzyle, BZM, CAS-120-51-4, SMR000471875, Benzylester kyseliny benzoove [Czech], Bengal, benzyl-benzoate, Benzyl benzoat, 1dzm, Benylate (TN), Benzoesaurebenzylester, Spectrum_001240, Benzoic acid-benzyl ester, Spectrum2_000532, Spectrum3_001757, Spectrum4_000773, Spectrum5_001128, WLN: RVO1R, Benzyl benzoate, >=99%, SCHEMBL3038, BENZYL BENZOATE [MI], BSPBio_003494, KBioGR_001186, KBioSS_001720, MLS001066412, MLS001336003, MLS001336004, BENZYL BENZOATE [FCC], BENZYL BENZOATE [JAN], DivK1c_000204, SPECTRUM1503002, SPBio_000543, Benzyl benzoate (JP17/USP), BENZYL BENZOATE [FHFI], BENZYL BENZOATE [HSDB], BENZOIC ACID,BENZYL ESTER, HMS500K06, KBio1_000204, KBio2_001720, KBio2_004288, KBio2_006856, KBio3_002714, BENZYL BENZOATE [WHO-DD], BENZYL BENZOATE [WHO-IP], NSC8081, NINDS_000204, HMS1921P16, HMS2092F20, HMS2269D24, Pharmakon1600-01503002, HY-B0935, Tox21_111372, Tox21_201337, Tox21_303418, BDBM50134035, CCG-39578, NSC758204, s4599, STL183088, BENZYL BENZOATE [ORANGE BOOK], AKOS003495939, Benzyl benzoate, >=99%, FCC, FG, Tox21_111372_1, DB00676, NSC-758204, BENZYLIS BENZOAS [WHO-IP LATIN], IDI1_000204, Benzyl benzoate, for synthesis, 99.0%, NCGC00094981-01, NCGC00094981-02, NCGC00094981-04, NCGC00094981-05, NCGC00094981-07, NCGC00257502-01, NCGC00258889-01, AC-17033, LS-14279, SBI-0051748.P002, DB-041563, B0064, inverted exclamation markY99%, refined grade, NS00006239, Benzyl benzoate, natural, >=99%, FCC, FG, Benzyl benzoate, ReagentPlus(R), >=99.0%, Benzyl benzoate, SAJ first grade, >=98.0%, Benzyl benzoate, tested according to Ph.Eur., Benzyl benzoate, SAJ special grade, >=99.0%, D01138, G73904, AB00052298_07, Benzyl benzoate, Vetec(TM) reagent grade, 98%, EN300-7323193, Benzyl benzoate, meets USP testing specifications, Q413755, SR-01000763773, Benzoic acid-benzyl ester 5000 microg/mL in Hexane, Q-200696, SR-01000763773-2, BRD-K52072429-001-06-1, BRD-K52072429-001-10-3, BRD-K52072429-001-11-1, BRD-K52072429-001-12-9, Z19825582, Benzoic acid-benzyl ester 100 microg/mL in Acetonitrile, Benzyl benzoate, certified reference material, TraceCERT(R), Benzyl benzoate, United States Pharmacopeia (USP) Reference Standard, Benzyl benzoate, Pharmaceutical Secondary Standard, Certified Reference Material, InChI=1/C14H12O2/c15-14(13-9-5-2-6-10-13)16-11-12-7-3-1-4-8-12/h1-10H,11H, Benzyl benzoate ReagentPlus(R), >=99.0%,Benzyl benzoate Vetec(TM) reagent grade, 98%,Benzoic acid benzyl ester≥ 99% (GC),VANZOATE(R),VENZONATE(R),Benylate,Benzyl alcohol benzoic ester,Benzyl ester

Benzyl Benzoate is also toxic to mite ova through an unknown mechanism.
Benzyl Benzoate is capable of killing the mite in 5 minutes.
Its mechanism of action is through exerting toxic effect on the nervous system of the insects, further causing its death.

It can also be used as a repellent for chiggers, ticks, and mosquitoes as well as a dye carrier, solvent of cellulose derivatives, plasticizer, and a fixative.
Benzyl Benzoate is a perfuming agent with a sweet but faint balsamic smell.
It can be found in a variety of cosmetic and personal care products including baby care to enhance user experience.
This ingredient is also a potent solvent with antimicrobial properties that protect the skin and increase the shelf life of products.

However, Benzyl Benzoate has allergen potential and is known to irritate the skin.
Benzyl Benzoate is not friendly to sensitive skin as it can penetrate deep within and disrupt the skin’s naturally protective lipids.
Due to this, in most products, it is permissible to be used only in very low concentrations.

The chemical formula of Benzyl Benzoate is C14H12O2.
Benzyl Benzoate is a clear, colorless, oily liquid with a light, balsamic odor reminiscent of almond and a sharp, pungent taste.
Benzyl Benzoate produces a sharp, burning sensation on the tongue.

At temperatures below 178℃ it exists as clear, colorless crystals.
Benzyl Benzoate is an organic compound which is used as a medication and insect repellent.
As a medication it is used to treat scabies and lice.

For scabies either permethrin or malathion is typically preferred.
Benzyl Benzoate is applied to the skin as a lotion.
Typically two to three applications are needed.

Benzyl Benzoate is also present in Balsam of Peru, Tolu balsam, and in a number of flowers.
Side effects may include irritation of the skin.
Benzyl Benzoate is not recommended in children.

Benzyl Benzoate is also used in other animals; however, it is considered toxic to cats.
Benzyl benzoate was first studied medically in 1918.
Benzyl Benzoate is on the World Health Organization's List of Essential Medicines.

Benzyl Benzoate is sold under the brand name Scabanca among others and is available as a generic medication.
Benzyl Benzoate is not available for medical use in the United States.
Benzyl benzoate is the ester of benzyl alcohol and benzoic acid, with the formula C6H5CH2O2CC6H5.

This easily prepared compound with a mild balsamic odor has a variety of uses.Benzyl benzoate (BB) is one of the oldest drugs used for the treatment of scabies and is recommended as the “first-line intervention” for the cost-effective treatment of the disease.
Benzyl Benzoate is an organic compound with the chemical formula C14H12O2.
Benzyl Benzoate is an ester formed from benzoic acid and benzyl alcohol.

Benzyl Benzoate is the main component of Peru balsam oil.
It occurs in fairly large amounts in a number of blossom concretes and absolutes (e.g., tuberose and hyacinth).
Benzyl Benzoate forms either a viscous liquid or solid flakes (mp 21–22°C) and has a weak, sweet, balsamic odor.

Benzyl Benzoate is prepared either by transesterification of technical methyl benzoate with benzyl alcohol or from benzyl chloride and sodium benzoate.
A third process starts with benzaldehyde, which is converted in high yield into benzyl benzoate in the presence of sodium or aluminum benzylate (Tishchenko reaction).
Benzyl benzoate is used in perfumery as a fixative and as a modifier in heavy blossom fragrances.

Contained in Peru balsam and in the concrete and absolute of tuberose flowers, hyacinth, Narcissus jonquilla L., and Dianthus caryophillus L.; also in the oil of ylang-ylang and in Tolu balsam.
Reported found in American cranberry, cinnamon bark, cassia leaf, corn oil and hog plum (Spondias mombins L.).
Benzyl Benzoate is an aromatic chemical, usually appearing as a clear liquid with a mild sweet-balsamic fragrance.

Benzyl Benzoate appears as a component of some of our fragrance blends.
Benzyl benzoate is a synthetic chemical produced for industry from benzyl alcohol and benzoic acid, but is also naturally present in the essential oils of many plants, including cinnamon, balsam of peru and ylang ylang.
Benzyl Benzoate often appears in fragrances, either as a synthetic additive used as a fixative to help preserve the longevity of a fragrance, or as a natural component of the essential oils used in the fragrance.

This ingredient is also used in medicine for the topical treatment of some skin conditions.
Studies indicate a small percentage of people can be sensitive to this ingredient, which is why we list in when it's detected in fragrances, though it only appears at very low concentrations, within the safe use defined by the International Fragrance Association (IFRA).
The IFRA is a self-regulatory representative body of the fragrance industry, dedicated to promoting the safe use of fragrances.

Benzyl benzoate is a benzoate ester obtained by the formal condensation of benzoic acid with benzyl alcohol.
Benzyl Benzoate has been isolated from the plant species of the genus Polyalthia.
It has a role as a scabicide, an acaricide and a plant metabolite.

Benzyl Benzoate is a benzyl ester and a benzoate ester.
Benzyl Benzoate is functionally related to a benzoic acid.
By the dry esterification of sodium benzoate and benzoyl chloride in the presence of triethylamine or by reaction of sodium benzylate on benzaldehyde.

Benzyl benzoate is one of the older preparations used to treat scabies.
Scabies is a skin infection caused by the mite sarcoptes scabiei.
Benzyl Benzoate is characterised by severe itching (particularly at night), red spots, and may lead to a secondary infection.

Benzyl benzoate is lethal to this mite and so is useful in the treatment of scabies.
Benzyl Benzoate is also used to treat lice infestation of the head and body.
Benzyl Benzoate is not the treatment of choice for scabies due to its irritant properties.

Benzyl Benzoate is produced from benzyl alcohol and sodium benzoate in the presence of triethylamine or by transesterification of methyl benzoate with benzyl alcohol in the presence of an alkali benzyl oxide.
In another manufacturing process benzaldehyde is condensed to form benzyl benzoate in the presence of sodium (Claisen-Tishchenko condensation).
The presence of a small amount of an aliphatic ether improves this reaction.

Benzyl benzoate is a byproduct in the manufacture of benzoic acid by the oxidation of toluene; it is present in the benzoic acid distillation residue.
Benzyl benzoate is used as a solubilizing agent and nonaqueous solvent in intramuscular injections at concentrations of 0.01–46.0% v/v, and as a solvent and plasticizer for cellulose and nitrocellulose.
It is also used in the preparation of spray-dried powders using nanocapsules.

However, the most widespread pharmaceutical use of benzyl benzoate is as a topical therapeutic agent in the treatment of scabies.
Benzyl benzoate is also used therapeutically as a parasiticide in veterinary medicine.
Other applications of benzyl benzoate include its use as a pediculicide, and as a solvent and fixative for flavors and perfumes in cosmetics and food products.

Benzyl benzoate is the condensation product of benzoic acid and benzyl alcohol.
Benzyl Benzoate is utilized for treating human scabies as well as kills house dust mite.
Benzyl benzoate is a naturally occurring ester obtained fromPeru balsam and other resins.

Benzyl Benzoate is also prepared syntheticallyfrom benzyl alcohol and benzoyl chloride.
The ester isa clear colorless liquid with a faint aromatic odor.
Benzyl Benzoate is insolublein water but soluble in organic solvents.

Benzyl benzoate is an effective scabicide when appliedtopically.
Immediate relief from itching probably resultsfrom a local anesthetic effect; however, a complete cureis frequently achieved with a single application of a 25%emulsion of benzyl benzoate in oleic acid, stabilized withtriethanolamine.
This preparation has the additionaladvantage of being essentially odorless, nonstaining, andnonirritating to the skin.

Benzyl Benzoate is applied topically as a lotionover the entire dampened body, except the face.
Benzyl Benzoate is a unique ingredient with anti bacterial and fragrance properties, finding extensive use in skin care and cosmetics.
Benzyl Benzoate is used in skin care for its antiparasitic and anti-inflammatory properties.

Benzyl Benzoate effectively treats scabies and lice infestations by killing the mites and lice.
Additionally, its soothing properties help reduce skin irritation and inflammation, providing relief from itching and discomfort associated with these conditions.
In cosmetics, Benzyl Benzoate functions as a solvent and fragrance ingredient.

Benzyl Benzoate helps dissolve other ingredients, improving the texture and application of products.
Its mild antimicrobial properties also enhance the preservation of formulations, making it a valuable component in perfumes, creams, lotions, and other cosmetic products.
Commonly used as a solvent for various medications and in topical treatments for conditions like scabies and lice.

Employed in the cosmetic industry as a fragrance component and in food products for flavoring.
Benzyl Benzoate utilized as a plasticizer, which helps increase the flexibility and durability of materials.
Acts as an active ingredient in some insect repellent formulations.

Melting point: 17-20 °C (lit.)
Boiling point: 323-324 °C (lit.)
Density: 1.118 g/mL at 20 °C (lit.)
vapor pressure: 1 mm Hg ( 125 °C)
refractive index: n20/D 1.568(lit.)
FEMA: 2138 | BENZYL BENZOATE
Flash point: 298 °F
storage temp.: 2-8°C
solubility: Miscible with ethanol, alcohol, chloroform, ether, oils.
form: Liquid
color: Clear colorless
Odor: at 100.00 %. faint sweet balsam oily herbal
Odor Type: balsamic
Water Solubility: practically insoluble
Merck: 14,1127
JECFA Number: 24
BRN: 2049280
Dielectric constant: 4.8（20℃）
Stability: Stable. Substances to be avoided include strong oxidizing agents. Combustible.
InChIKey: SESFRYSPDFLNCH-UHFFFAOYSA-N
LogP: 4 at 20℃
CAS DataBase Reference 120-51-4(CAS DataBase Reference)
Substances Added to Food (formerly EAFUS): BENZYL BENZOATE

Benzyl Benzoate is a constituent of Peru balsam and occurs naturally in certain plant species.
Commercially, benzyl benzoate is produced synthetically by the dry esterification of sodium benzoate and benzoyl chloride in the presence of triethylamine or by the reaction of sodium benzylate with benzaldehyde.
In man, Benzyl Benzoate was a skin sensitizer and caused gastro-intestinal effects in an infant.

Benzyl Benzoate was of moderate to low acute oral toxicity in a range of laboratory animal species and of low acute dermal toxicity in rabbits.
Central nervous system effects were induced in several species given single doses orally or dermally.
Repeated skin applications caused degenerative changes in various organs (including the liver, spleen and testes) of rabbits.

No effects were seen in reproductive studies involving repeated oral administration to rats during pregnancy and lactation.
Benzyl Benzoate gave no evidence of mutagenicity in an Ames bacterial assay.
It was a mild skin irritant in rabbits.

Benzyl Benzoate is produced by the Cannizzaro reaction from benzaldehyde, by esterifying benzyl alcohol with benzoic acid, or by treating sodium benzoate with benzyl chloride.
Benzyl Benzoate is purified by distillation and crystallization. Benzyl benzoate is used as a fixative and solvent for musk in perfumes and flavors, as a plasticizer, miticide, and in some external medications.
The compound has been found effective in the treatment of scabies and pediculosis capitis (head lice, Pediculus humanus var. capitis).

This agent is relatively nontoxic and is widely used in developing countries to treat scabies and pediculosis capitis and pubis.
Only a veterinary preparation is available in the United States.
Benzyl Benzoate is synthetically derived from the esterification of benzoic acid with benzyl alcohol.

Its mechanism of action is unknown.
Benzyl Benzoate is toxic to Sarcoptes scabei and may be toxic to Pediculosis capitis and Phthirus pubis.
Benzyl benzoate can be used in a 5% emulsion to repel many arthropods and can be used as a lotion to treat sarcoptic mange and canine pediculosis.

Benzyl benzoate is the ester of benzyl alcohol and benzoic acid.
Benzyl Benzoate is contained in Myroxylon pereirae and Tolu balsam.
Benzyl Benzoate is used in acaricide preparations against Sarcoptes scabiei or as a pediculicide.

Direct contact may cause skin irritation, but rarely allergic contact dermatitis.
As a fragrance allergen, benzyl benzoate has to be mentioned by name in EU cosmetics.
Benzyl Benzoate is a naturally occurring ester obtained fromPeru balsam and other resins.

Benzyl Benzoate is also prepared syntheticallyfrom benzyl alcohol and benzoyl chloride.
The ester isa clear colorless liquid with a faint aromatic odor. It is insolublein water but soluble in organic solvents.
Benzyl benzoate is an effective scabicide when appliedtopically.

Immediate relief from itching probably resultsfrom a local anesthetic effect; however, a complete cureis frequently achieved with a single application of a 25%emulsion of benzyl benzoate in oleic acid, stabilized withtriethanolamine.
This preparation has the additionaladvantage of being essentially odorless, nonstaining, andnonirritating to the skin.
Benzyl Benzoate is applied topically as a lotionover the entire dampened body, except the face.

Benzyl benzoate has low acute toxicity in laboratory animals.
Benzyl Benzoate is rapidly hydrolyzed to benzoic acid and benzyl alcohol.
Benzyl Benzoate is subsequently metabolized to benzoic acid.

The conjugates of benzoic acid (hippuric acid and the glucuronide of benzoic acid) are rapidly eliminated in urine.
When given in large doses to laboratory animals, benzyl benzoate can cause hyperexcitation, loss of coordination, ataxia, convulsions, and respiratory paralysis.
Benzyl benzoate can be a skin irritant when used as a topical scabicide.

Overdose can result in blistering and hives or a rash can occur as an allergic reaction.
As an excipient in some testosterone-replacement injectable medications, Benzyl Benzoate has been reported as a cause of anaphylaxis in a case in Australia.
Bayer includes this report in information for health professionals and recommends that physicians "should be aware of the potential for serious allergic reactions" to preparations of this type.

In Australia, reports to ADRAC, which evaluates reports of adverse drug reactions for the Therapeutic Goods Administration, show several reports of allergic issues since the anaphylaxis case from 2011.
Benzyl benzoate is an organic compound which is used as a medication and insect repellent.
As a medication it is used to treat scabies and lice.

Benzyl Benzoate is applied to the skin as a lotion.
Typically two to three applications are needed.
Benzyl Benzoate is also present in Balsam of Peru, Tolu balsam, and in a number of flowers.

Side effects may include irritation of the skin.
Benzyl Benzoate is not recommended in children.
Benzyl Benzoate is also used in other animals; however, it is considered toxic to cats.

How it works is unclear. Benzyl benzoate was first studied medically in 1918.
Benzyl Benzoate is on the World Health Organization's List of Essential Medicines.
Benzyl Benzoate is sold under the brand name Scabanca among others and is available as a generic medication.

Benzyl Benzoate is not available for medical use in the United States.
Can cause irritation upon contact with skin or eyes.
Respiratory Issues: Inhalation of vapors can lead to respiratory irritation.

May be harmful if ingested or absorbed through the skin in large amounts.
Use personal protective equipment (PPE) like gloves and goggles when handling.
Ensure adequate ventilation in areas where it is used.

Follow appropriate disposal methods as it may be hazardous to aquatic life.
Benzyl Benzoate can be naturally derived from plants such as plumeria and cinnamon.
But for cosmetics, it is usually made synthetically through the esterification of benzoic acid with benzyl alcohol.

This process typically involves heating the two compounds together in the presence of an acid catalyst, such as sulfuric acid or hydrochloric acid, which facilitates the reaction.
The mixture is then distilled to purify the Benzyl Benzoate.

Uses:
Benzyl Benzoate has seen use as an insecticide, as well as a solvent for various chemical reactions.
Benzyl benzoate is a benzyl compound that can be synthesized by reacting benzyl chloride with sodium benzoate in the presence of tetrabutylaramonium iodide.
Benzyl Benzoate solution employed for enhancing the tissue transparency during the whole-mount immunostaining BABB method.

Study its ability to induce an olfactory response in the third instar larvae of Drosophila melanogaster.
Prepare Spalteholz fluid in combination with methyl salicylate, employed during LSFM (light sheet fluorescence microscopy) imaging.
Benzyl Benzoate is an effective and inexpensive topical treatment for human scabies.

Benzyl Benzoate has vasodilating and spasmolytic effects and is present in many asthma and whooping cough drugs.
Benzyl Benzoate is also used as an excipient in some testosterone-replacement medications (like Nebido) for treating hypogonadism.
Benzyl benzoate is used as a topical acaricide, scabicide, and pediculicide in veterinary hospitals.

Benzyl Benzoate is used as a repellent for chiggers, ticks, and mosquitoes.
Benzyl Benzoate is also used as a dye carrier, solvent for cellulose derivatives, plasticizer, and fixative in the perfume industry.
Benzyl benzoate, as a topical solution, may be used as an antiparasitic insecticide to kill the mites responsible for the skin condition scabies , for example as a combination drug of benzyl benzoate/disulfiram.

Benzyl Benzoate fixative in fragrances to improve the stability and other characteristics of the main ingredients.
Benzyl Benzoate is an anti-microbial.
It can also act as a solvent, helping dissolve other substances in the product, and as a perfuming ingredient.

Benzyl Benzoate is the ester of benzyl alcohol and benzoic acid.
As solvent of cellulose acetate, nitrocellulose and artificial musk; substitute for camphor in celluloid and plastic pyroxylin Compounds; perfume fixative; in confectionery and chewing gum flavors.
Used as a treatment for scabies and lice due to its insecticidal properties.

Solvent for Medications: Serves as a solvent in various pharmaceutical formulations, helping dissolve other active ingredients.
Commonly used in perfumes, lotions, and creams to impart a pleasant scent.
Acts as a skin-conditioning agent, providing moisturizing properties.

Employed as a flavoring agent in certain food products due to its pleasant aroma.
Benzyl Benzoate is used to enhance the flexibility and durability of plastics and resins.
Functions as an additive in various coatings, improving properties like gloss and flexibility.

Found in some formulations aimed at pest control, acting as a repellent or insecticide.
Acts as an intermediate in the synthesis of other organic compounds, including certain fragrances and pharmaceuticals.
Employed in laboratories for various experimental applications, including studies related to its chemical properties.

Safety profile:
Benzyl Benzoate is generally considered safe for use when used at appropriate concentrations.
Benzyl Benzoate is well-tolerated by most individuals, but can cause skin irritation or allergic reactions in sensitive users.
Overuse or high concentrations may lead to toxicity, particularly in children.

Patch testing the product containing Benzyl Benzoate is required.
Benzyl Benzoate is metabolized by rapid hydrolysis to benzoic acid and benzyl alcohol.
Benzyl Benzoate is then further metabolized to hippuric acid, which is excreted in the urine.

Benzyl benzoate is widely used as a 25% v/v topical application in the treatment of scabies and as an excipient in intramuscular injections and oral products.
Adverse reactions to benzyl benzoate include skin irritation and hypersensitivity reactions.
Benzyl Benzoate should be avoided by perople with perfume allergy.