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CAS NUMBER: 590-46-5
MOLECULAR WEIGHT: 153.61
Betaine hydrochloride is a chemical compound that helps support digestion in the stomach by acting as a supplemental source of hydrochloric acid, also known as stomach acid.** From a leader in betaine HCL supplements, Country Life offers a formula focused on helping to increase good stomach acid, while also providing additional support through the following important digestive enzymes: pepsin, papain from papaya and bromelain from pineapple.
Betaine hydrochloride is a chemical substance made in a laboratory.
Betaine hydrochloride is used as medicine.
Betaine hydrochloride has an interesting history.
Betaine hydrochloride used to be included in over-the-counter (OTC) products as a “stomach acidifier and digestive aid.”
But a federal law that went into effect in 1993 banned betaine hydrochloride from use in OTC products because there wasn’t enough evidence to classify it “generally recognized as safe and effective.” Betaine hydrochloride is now available only as a dietary supplement whose purity and strength can vary.
Promoters still claim that some health conditions are due to inadequate stomach acid, but this claim has not been proven.
Even if it were true, betaine hydrochloride wouldn’t help.
Betaine hydrochloride only delivers hydrochloric acid but does not itself alter stomach acidity.
Betaine hydrochloride is also used to treat abnormally low levels of potassium (hypokalemia), hay fever, “tired blood” (anemia), asthma, “hardening of the arteries” (atherosclerosis), yeast infections, diarrhea, food allergies, gallstones, inner ear infections, rheumatoid arthritis (RA), and thyroid disorders. It is also used to protect the liver.
Betaine Hydrochloride is the hydrochloride form of betaine, a crystalline alkaloid occurring in sugar beets and other plants.
Betaine, acting as a transmethylating metabolic intermediate, is the oxidation product of choline.
Betaine hydrochloride is used as a gastric acidifier supplement.
A naturally occurring compound that has been of interest for its role in osmoregulation.
As a drug, betaine hydrochloride has been used as a source of hydrochloric acid in the treatment of hypochlorhydria.
Betaine hydrochloride has also been used in the treatment of liver disorders, for hyperkalemia, for homocystinuria, and for gastrointestinal disturbances.
Betaine hydrochloride is a vitamin-like substance that is a source of hydrochloric acid and aids the production of stomach acid.
Gastric acid also helps protect the gastrointestinal tract from harmful bacteria.
A normal level of gastric acid in the stomach—100,000-1,000,000 times more acidic than water—is sufficient to destroy bacteria, but some people produce deficient amounts of stomach acid, a condition that may lead to bacterial and parasitic infections of the intestines.
One study showed that fasting people with normal gastric acid levels in the stomach had almost no bacteria in the small in- testine, while individuals with low levels of hydrochloric acid had some bacterial colonization in the stomach.
Betaine hydrochloride is therefore recommended by some medical practitioners to sustain a healthy and normal production of stomach acid, especially to those that suffer from disorders such as allergies and asthma.
Betaine hydrochloride is a synthesized chemical, and is not obtained from any plant or animal source.
Betaine hydrochloride is produced by stomach cells, and is not available from any food source.
Occasionally, betaine (C5H11NO2 )is recommended to reduce blood levels of homocysteine, which is associated with heart disease.
This form of Betaine hydrochloride is different from betaine hydrochlo- ride, and is available only with a doctor’s prescription.
Don’t confuse betaine hydrochloride with betaine anhydrous.
Use only the FDA-approved betaine anhydrous product for the treatment of high levels of homocysteine in the urine (homocystinuria).
This is a symptom of some rare genetic diseases.
Betaine hydrochloride (also known as betaine HCI or betaine HCL) is a chemical compound produced in laboratories.
Betaine hydrochloride is believed to increase stomach acid.
In the past, betaine hydrochloride could be found in over-the-counter (OTC) digestive aids as a source of hydrochloric acid, a key component of stomach juices that some people are low on.
However, in the late 1980s, the Food and Drug Administration (FDA) banned betaine hydrochloride from use in OTC products because there was not sufficient evidence for it to be considered “generally recognized as safe and effective.”
Although you can still find betaine HCL in the form of a dietary supplement, few studies have been done to elucidate what effects it may have.
Betaine hydrochloride is a nutritional compound extracted from food sources like grains or beets.
Betaine hydrochloride is an acidic version of betaine that works in the same way as hydrochloric acid (HCl) in your stomach.
Betaine hydrochloride temporarily increases acid levels in the stomach (that’s the same thing as a lower pH).
This effect lasts a few hours, at least in one study of volunteers taking acid-suppressing drugs.
Because of this, betaine hydrochloride has been used to help absorption of some medications.
However, there is no convincing evidence that this helps with symptoms.
An individual person’s response could be due to the placebo effect, meaning that the difference you noted could be due to expecting to find some benefit from taking the supplement.
Betaine hydrochloride does not have many side-effects in most people.
Nausea, stomach upset, diarrhea and a body odour all have been reported.
As a dietary supplement, Betaine hydrochloride is sometime combined with digestive enzymes such as pepsin or protease to help with protein digestion.
Betaine hydrochloride is provided as delivered and specified by the issuing Pharmacopoeia.
All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.
For further information and support please go to the website of the issuing Pharmacopoeia.
Betaine hydrochloride is a methyl group donor that functions in the normal metabolic cycle of methionine and reduces homocystinuria in patients with inborn errors of methionine metabolism.
In the United States, betaine is distributed under the brand name Cystadane by Rare Disease Therapeutics.
Many reports have shown that betaine's therapeutic effectiveness is limited, and does not lower tHcy levels or prevent clinical symptoms.
Betaine hydrochloride is a source of hydrochloric acid, which promotes optimal gastric acidity to support protein digestion and absorption of minerals and other nutrients.
Betaine hydrochloride provides a supplemental source of hydrochloric acid, an acidifying compound normally produced by the stomach during digestion of foods.
Betaine hydrochloride should only be taken by people who have reduced levels of stomach acid. Each 648 mg capsule is equivalent to a measurement of 10 grains.
Betaine hydrochloride is a natural substance that is present in various plants, including sugar beet, while the body obtains betaine from its metabolic precursor, choline.
Betaine hydrochloride contributes to normal homocysteine metabolism, a cardiovascular risk factor.
In addition, betaine has lipotropic activities that improve the conditions of hepatic steatosis, also with its hepatoprotective action.
Betaine hydrochloride is used as adjuvant for digestive processes, particularly to reduce symptoms associated with low production of hydrochloric acid.
Betaine Hydrochloride is an acidic form of Betaine and is often used to support levels of stomach acid.
Pepsin is produced in the stomach and is one of the main digestive enzymes helping to digest proteins in food.
Betaine hydrochloride is a known functional nutrient in broiler nutrition, which was in the past mainly used as betaine anhydrous extracted from sugar beets.
Nowadays, Betaine hydrochloride is also available as betaine hydrochloride from synthetic production.
Betaine hydrochloride is eliminated by metabolism, not excretion, and catabolised via a series of enzyme reactions (transmethylation) that occur in the mitochondria of liver and kidney cells.
The principal physiologic role of betaine is to act as an osmolyte and as methyl donor (transmethylation).
As an osmolyte (dipolar zwitterion characteristics), Betaine hydrochloride increases intracellular water retention and therefore protects intracellular enzymes against osmotic induced inactivation.
As a methyl donor, Betaine hydrochloride participates in the methionine cycle (mainly in the liver) and can be further used in transmethylation reactions for synthesis of essential substances like carnitine and creatine.
Betaine Hydrochloride is a chemical substance made in a laboratory by combining betaine and hydrochloric acid (HCl).
Betaine hydrochloride’s sold as a supplement source of hydrochloric acid for those who may have low acid in the stomach.
A healthy stomach can produce enough Betaine hydrochloride to support digestion, nutrient absorption, and immunity.
With age or under certain health conditions, people can suffer a deficiency of hydrochloric acid making them susceptible to various infections, indigestion, and other gastrointestinal problems.
Betaine hydrochloride is crucial for bile secretion which plays a role in detoxification and digestion.
Both betaine and HCl are crucial for the breakdown of fat and disposal of chemicals that accumulate in our body and thus protect the liver and gallbladder.
Supplementation of Betaine hydrochloride may be beneficial to those with inadequate production of HCl.
Betaine hydrochloride may help improve digestion by increasing the level of hydrochloric acid in the stomach.
Betaine hydrochloride helps break down fats, proteins, and other complex nutrients during digestion and assimilation of these nutrients into our body.
The main role of Betaine hydrochloride is to maintain a proper level of acids in the stomach.
Stomach acid is an important part of our immune system that kills the potentially dangerous pathogens in food.
Betaine hydrochloride prevents us from getting various infections and its deficiency could cause vulnerabilities.
Betaine hydrochloride has been used as a source of hydrochloric acid in the treatment of hypochlorhydria, a condition in which an abnormally low amount of hydrochloric acid is in the stomach.
Betaine hydrochloride has been used in preparations for the treatment of liver disorders, hypokalaemia (abnormally low levels of potassium in the blood), CO2 production in double contrast radiography, and high homocysteine.
Betaine hydrochloride has also been used to treat tic douloreux (a condition which involves spasmodic pain along the course of a facial nerve), cystinuria (a hereditary defect that results in recurrent kidney stone formation), and vitiligo (a condition that is characterized by milky-white patches on otherwise normal skin).
Hydrochloric acid is an integral part of the digestive process but illness, poor diet (especially diets that are too acidic), overuse of antacids and stress can throw off the proper levels of its production.
The symptoms of too little and too much hydrochloric acid often manifest with similar symptoms: acid reflux, heartburn, gas and other gastrointestinal discomforts.
Low stomach acid is often the factor causing discomfort.
With inadequate hydrochloric acid production, proteins will not be properly digested and the innate minerals, vitamins and other micronutrients will not be properly absorbed.
Hydrochloric acid is also a critical immune defense, destroying pathogens in food.
A lessened amount or lack of Hcl contributes to bacterial and fungal dysbiosis in the gut.
This contributes to an imbalance in several metabolic pathways and the resulting disorders and symptoms often considered diseases.
Betaine hydrochloride, taken with meals, will eventually stimulate the body to restart innate production of hydrochloric acid.
Betaine hydrochloride is found in animals and plants and is especially high in beets (the name betaine is so called because it was first discovered in sugar beets), spinach and grains. Its primary role is to protect cellular integrity from stressors.
In addition to digestive disorders, betaine may increase energy levels and help metabolize fatty acids.
Because Betaine hydrochloride is a methyl donor, supplementation with Betaine HCl helps reduce levels of homocysteine, high levels of which are believed to be associated with heart disease.
Betaine hydrochloride is used by some health care practitioners to treat low levels of potassium, food allergies and hay fever, anemia, asthma, gallstones, rheumatoid arthritis and thyroid disorders.
Betaine hydrochloride is a powerful digestive aid.
Betaine hydrochloride's especially helpful for people who may have been privy to a poor diet, prolonged dehydration, and generalized stress.
Betaine hydrochloride has been shown to offer digestive support to perimenopausal women and elderly individuals.
Betaine hydrochloride is beneficial for addressing hypochlorhydria, a deficiency of stomach acid production.
Betaine hydrochloride is also a crucial compound in balancing homocysteine levels, a condition related to poor cardiovascular health.
As we age, the body naturally produces fewer digestive enzymes.
Due to reduced enzymatic activity, Betaine HCl levels decrease.
Depending on the individual, this can lead to sluggish digestion and poor nutrient absorption.
Betaine hydrochloride also means that the body is not detoxifying itself as well as it should. Things that the body would normally expel remain lodged in the system.
Betaine hydrochloride leads to toxic overload and systemic tissue irritation.
Many people facing poor digestion have found that taking plant-derived betaine HCl before a meal supports digestion.
Betaine hydrochloride contains approximately 23% hydrochloric acid, commonly known as stomach acid.
Betaine hydrochloride is naturally sourced from beets. Stomach acid initiates the digestive process by beginning the breakdown of food, especially protein.
Betaine hydrochloride is also an important protective mechanism against infection by killing any microbes that are contained in our food or water.
Low stomach acid impairs one’s ability to digest food by limiting the release and functioning of other digestive enzymes.
Although Betaine hydrochloride may seem contradictory, low stomach acid can also lead to gastric reflux (heartburn).
Closure of the valve at the top of the stomach is stimulated by the hydrochloric acid that is released in response to food intake.
In an individual with low stomach acid the valve does not close and allowing the remaining acid to push up into the esophagus and cause a burning sensation.
Betaine hydrochloride is recommended for indigestion, low stomach acid and gastric reflux.
Betaine hydrochloride can be purchased in capsules.
Betaine hydrochloride is found on its own or as a component of a digestive or multi-enzyme formula.
Betaine hydrochloride should be taken with meals and more may be necessary with large meals or those containing protein.
To assess you need for Betaine hydrochloride some practitioners recommend an HCl challenge test.
The number of Betaine hydrochloride capsules taken each day is increased by one until a slight burning sensation is felt in the stomach.
The appropriate daily dosage is slightly lower than the amount that causes burning.
This test should be done cautiously and under medical supervision if you have a gastrointestinal condition.
USES:
Betaine hydrochloride is an acidic form of betaine, a vitamin-like substance found in grains and other foods.
Betaine hydrochloride is recommended by some doctors as a supplemental source of hydrochloric acid for people who have a deficiency of stomach acid production (hypochlorhydria).
Betaine hydrochloride (HCl) may help to raise the level of acid in the stomach.
Betaine hydrochloride may also help with some bowel problems.
There is also a prescription drug, Betaine.
Betaine hydrochloride is not the same as this natural product.
Take extra care so you do not mix them up as they are used for different illnesses.
Betaine hydrochloride is used as gastric acidifier.naturopaths have long held that low stomach acid is a widespread problem that interferes with the digestion and absorption of nutrients.
Betaine hydrochloride is one of the most common recommendations for this condi- tion.
Betaine hydrochloride helps make some minerals and other nutrients more absorbable, and may be especially helpful with nu- tritional supplements, which are often taken in tablets or capsules that may not be easily digested.
Betaine hydrochloride (pronounced beta-een) is the acid form of trimethyiglycine (TMG).
The most common use of betaine hydrochloride is as digestive aid for people who suffer from low gastric acidity (hypochlorhydria), a common complaint in the elderly and a cause of chronic indigestion.
Although such a practice is unwise.
Betaine hydrochloride can be of use in cases of overeating.
Gourmands, in particular, suffer less discomfort after indulgences if they take betaine hydrochloride with their feasts.
Betaine hydrochloride is not only a digestive aid, but it also confers all the benefits of TMG (see next).
However, betaine hydrochloride should not be used by anyone with chronic indigestion or heartburn without first seeking medical evaluation of the problem to make sure that there is not a more serious underlying condition such as stomach ulcers.
Betaine hydrochloride should be taken only with meals, and then only after first eating a few bites of food.
The usual dose of betaine hydrochloride for hypochlorhydria is 500 milligrams which is equivalent to 1.1 cubic centimeter (about a quarter teaspoon) of pharmaceutical Dilute Hydrochloric acid.
-Anemia.
-Asthma.
-Diarrhea.
-Food allergies.
-Gallstones.
-Hay fever.
-"Hardening of the arteries" (atherosclerosis).
-Increasing stomach acid..
-Inner ear infection...
-Low potassium.
-Protecting the liver.
-Rheumatoid arthritis (RA).
-Thyroid disorders.
-Yeast infection.
-Other conditions.
BENEFITS:
Betaine hydrochloride is commonly marketed as a supplement that can be taken for a slew of conditions, but little research exists on its purported health benefits.
Some doctors may recommend Betaine hydrochloride as a source of hydrochloric acid for people who do not produce enough of it due to a health condition called hypochlorhydria.
Otherwise, despite many claims from promoters and alternative medicine practitioners, there is insufficient evidence that betaine HCL can be taken for any of the following reasons:
-Promote healthy stomach pH
-Enhance protein and vitamin absorption
-Reduce symptoms of gastroesophageal reflux disease (GERD)
-Reduce symptoms of food allergies
-Reduce symptoms of gallstones
-Support heart health
-Fortify joints
-Reduce symptoms of rheumatoid arthritis (RA)
-Improve asthma symptoms
-Protect the liver
-Fight yeast infections
-Improve digestion of fats, especially in those post-cholecystectomy (gallbladder removal surgery)
While Betaine hydrochloride does deliver hydrochloric acid, research has only revealed a short-term effect on stomach acid content.
Betaine hydrochloride may help counteract the effect of certain drugs and in turn aid in the absorption of other drugs, per a 2014 study.
That said, more studies are needed to fully examine this potential effect.
PROPERTIES:
-grade: pharmaceutical primary standard
-manufacturer/tradename: USP
-mp: 241-242 °C (lit.)
-Featured Industry: Pharmaceutical (small molecule)
-format: neat
-SMILES string: [Cl-].C[N+](C)(C)CC(O)=O
-InChI: 1S/C5H11NO2.ClH/c1-6(2,3)4-5(7)8;/h4H2,1-3H3;1H
FUNCTION:
Betaine hydrochloride and pepsin are naturally occurring gastric-juice components that render nutrients available for absorption and biological acitivity.
Specifically, Betaine hydrochloride is an acidic form of betaine, which promotes optimal gastric lumen acidity and pepsin is a protein-digesting enzyme that catalyzes the splitting of peptide bonds.
Betaine hydrochloride is an excellent source of hydrochloric acid, also known as stomach acid.
Supplementing with betaine HCl can be very beneficial, as insufficient production of hydrochloric acid is fairly widespread and often overlooked.
Certain situations, such as normal aging, can decrease the body’s natural production of HCl.
INDICATION:
Betaine hydrochloride may be used as a lipotropic. Lipotropics aid in preventing the accumulation of fat in the liver, and usually help in the detoxification of metabolic wastes and toxins.
They may be used to help with weight loss.
Betaine hydrochloride has been used as a source of hydrochloric acid in the treatment of hypochlorhydria, a condition in which an abnormally low amount of hydrochloric acid is in the stomach.
Betaine hydrochloride has been used in preparations for the treatment of liver disorders, hypokalaemia (abnormally low levels of potassium in the blood), CO2 production in double contrast radiography, and high homocysteine.
Betaine hydrochloride has also been used to treat tic douloreux (a condition which involves spasmodic pain along the course of a facial nerve), cystinuria (a hereditary defect that results in recurrent kidney stone formation), and vitiligo (a condition that is characterized by milky-white patches on otherwise normal skin).
PREPARATION:
Betaine hydrochloride supplements are available in the form of tablets or capsules and can also be bought in bulk as a powder, which is more absorbable.
Currently, there is no recommended dosage for betaine HCL.
As such, the amount found in supplements can vary quite a bit.
Often, you’ll find betaine HCL in supplements that also contain pepsin, a digestive enzyme.
If you’re considering adding a betaine HCL supplement to your treatment regimen, make sure to talk to your doctor and pharmacist before you make a big purchase.
With their help, you can make an educated decision in light of any potential risks or medication interactions based on your personal medical history.
Betaine hydrochloride’s important to keep in mind that little is known about betaine HCL and how it may (or may not) work for various health conditions.
In light of this reality, it’s essential that you consult with a healthcare professional before you start taking it.
Betaine hydrochloride (also called betaine HCl) is typically taken in tablets or capsules of 5-10 grains (325-650 mg) each with a meal that contains protein.
Naturopathic or nutritionally oriented physicians may make recommendations of such tablets based on their diagnoses.
Betaine hydrochloride is an Acidic form of Betaine (Trimethylglycine), widely used in the aquaculture and animal feed industry to promote feed intake and stimulation, aid digestion and nutrition intake.
Our Betaine hydrochloride is a 98% pure, white crystalline powder.
SYNONYM:
Pluchine
Acinorm
Acipepsol
Acidin
Aciventral forte
Lycine hydrochloride
Acidogeno
Achylin
Acidol
Betaine HCl
Cystadane
ACIDINE
Acidol-Pepsin
(Carboxymethyl)trimethylammonium chloride
Glycine betaine hydrochloride
