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Bis(3-aminopropyl)dodecylamine, also called N,N-bis(3-aminopropyl)dodecylamine and laurylamine dipropylenediamine, is dodecylamine substituted with 2 propylamine units.
Bis(3-aminopropyl)dodecylamine is a non-ionic surfactant, antimicrobial agent, preservative, emulsifying agent, dispersing agent, corrosion inhibitor and an anti-static agent used in hair products.
Bis(3-aminopropyl)dodecylamine is an organic compound in the class of dodecylamines.
CAS Number: 2372-82-9
Molecular Formula: C18H41N3
Molecular Weight: 299.54
EINECS Number: 219-145-8
Synonyms: Bis(aminopropyl)laurylamine,1,3-Propanediamine, N-(3-aminopropyl)-N-dodecyl-,LONZABAC12.100,N-3-AMINOPROPYL-N-DODECYL-1,3-PROPANEDIAMINE,N-(3-Aminopropyl)-N-dodecylpropan-1,3-diamin,3-Propanediamine, N-(3-aminopropyl)-N-dodecyl-1,N,N-Bis-(3-aminopropyl)-laurylamine,methylenediamine
Bis(3-aminopropyl)dodecylamine is a colourless liquid although commercial samples can appear yellow and exhibit an amine-like odour.
Bis(3-aminopropyl)dodecylamine is a widely applied ingredient in many products, such as in surfactants, antimicrobials, preservatives, emulsifiers, corrosion inhibitors, chilling liquids, antistatics (e.g., in hair products), and dispersing agents.
In 2022, the EU decided upon not approving DPTA as an existing active substance for use in biocidal products of product-type 8, wood preservatives, due to the unacceptable risks for human health, and not having suitable risk mitigation measures.
Bis(3-aminopropyl)dodecylamine is a synthetic organic compound classified as a long-chain alkyl polyamine.
It consists of a dodecyl (C12) alkyl chain attached to two 3-aminopropyl groups, giving it both hydrophobic (water-repelling) and hydrophilic (water-attracting) properties.
This dual nature makes it highly effective as a surfactant, corrosion inhibitor, and antimicrobial agent in various industrial and commercial applications.
Its chemical formula is C18H41N3, and it is often used in formulations where surface activity, emulsification, and chemical reactivity are required.
The presence of amine functional groups allows it to interact with acids, water, and other polar substances, making it an important additive in oil and gas, metalworking, cleaning products, and coatings.
Bis(3-aminopropyl)dodecylamine is a versatile and effective industrial chemical with applications in corrosion inhibition, microbial control, surfactant systems, and fuel additives.
However, due to its irritant, toxic, and environmental risks, it must be handled with caution.
By following proper safety guidelines, protective measures, and responsible disposal practices, industries can maximize its benefits while minimizing health and environmental hazards.
Bis(3-aminopropyl)dodecylamine is an organic compound classified as a long-chain alkyl polyamine.
It consists of a dodecyl (C12) alkyl chain attached to two 3-aminopropyl groups, giving it both hydrophobic and hydrophilic properties.
This molecular structure enables the compound to function as a surfactant, emulsifier, corrosion inhibitor, and antimicrobial agent in various industrial and commercial applications.
Bis(3-aminopropyl)dodecylamine is known for its surface activity, which allows it to interact with both water-based and oil-based substances.
Bis(3-aminopropyl)dodecylamine is widely used in oil and gas production, metal protection, industrial lubricants, coatings, and water treatment chemicals.
Due to its unique chemical properties, bis(3-aminopropyl)dodecylamine is widely used in industrial, commercial, and chemical applications, including corrosion prevention, antimicrobial formulations, and surfactant systems. Some of its most common uses include:
Bis(3-aminopropyl)dodecylamine is commonly used as a corrosion inhibitor in pipeline systems, drilling fluids, and refinery equipment.
It works by forming a protective film on metal surfaces, preventing oxidation, rusting, and degradation in harsh environments such as offshore drilling rigs and chemical processing plants.
This protection is especially important in systems exposed to high humidity, saltwater, and acidic gases (such as hydrogen sulfide and carbon dioxide).
Bis(3-aminopropyl)dodecylamine exhibits strong antimicrobial properties, making it useful in disinfectants, sanitizers, and preservatives.
It is effective against bacteria, fungi, and algae, which is why it is incorporated into water treatment systems, industrial cooling towers, and fuel preservation solutions.
It is also found in paints, coatings, and adhesives to prevent microbial degradation and biofouling.
Its ability to interact with both hydrophobic (oil-based) and hydrophilic (water-based) substances makes it an excellent emulsifier in cleaning products, industrial degreasers, and oil-water separation processes.
Bis(3-aminopropyl)dodecylamine is used in metalworking fluids, textile softeners, and anti-static agents to improve the stability of emulsions and dispersions.
Bis(3-aminopropyl)dodecylamine is added to diesel fuels, gasoline, and aviation fuels to prevent gumming, carbon deposits, and microbial growth in storage tanks.
Bis(3-aminopropyl)dodecylamine helps maintain fuel quality, enhances engine performance, and prevents injector clogging in diesel engines.
In lubricants and greases, it provides anti-wear and anti-corrosion properties.
It is a key ingredient in industrial coatings, epoxy resins, and adhesive formulations, particularly in applications that require chemical resistance, durability, and adhesion to metals or polymers.
Bis(3-aminopropyl)dodecylamine improves the performance of protective coatings used in marine, automotive, and aerospace industries.
While bis(3-aminopropyl)dodecylamine is highly effective in industrial applications, it can pose health and environmental risks if not handled properly.
Bis(3-aminopropyl)dodecylamine can cause severe irritation or chemical burns upon contact with the skin and eyes.
Prolonged exposure may lead to dermatitis, redness, swelling, or blistering.
Direct eye contact can result in pain, corneal damage, and temporary vision impairment.
If inhaled as a mist or vapor, it may cause coughing, throat irritation, and difficulty breathing.
High concentrations in poorly ventilated areas can lead to respiratory distress or chemical pneumonitis.
Ingestion can be harmful or toxic, causing gastrointestinal distress, nausea, vomiting, and internal damage.
If aspirated into the lungs, it may lead to aspiration pneumonia, a serious and potentially life-threatening condition.
Bis(3-aminopropyl)dodecylamine is considered harmful to aquatic life due to its toxicity to fish, algae, and other marine organisms.
If released into water sources, it can cause long-term contamination and bioaccumulation in the ecosystem.
Spillage on soil or industrial waste sites may lead to persistent contamination due to its low biodegradability.
Though not highly flammable, it may decompose at high temperatures, releasing toxic nitrogen oxides (NOx) and other hazardous fumes.
Bis(3-aminopropyl)dodecylamine reacts with strong acids, oxidizers, and other reactive chemicals, producing heat and potentially hazardous byproducts.
Gloves, goggles, and protective clothing should be used when handling.
Respiratory protection is recommended in aerosol-generating environments.
Store in cool, dry, well-ventilated areas away from heat, moisture, and incompatible chemicals.
Contain and neutralize spills using absorbent materials and proper chemical waste disposal procedures.
Boiling point: 182-184 °C(Press: 1 Torr)
Density: 0.880
vapor pressure: 0Pa at 25℃
solubility: 560g/L in organic solvents at 20 ℃
form: Oil
pka: 10.46±0.10(Predicted)
color: Colourless
Viscosity: 24.18mm2/s
Water Solubility: 190g/L at 20℃
InChI: InChI=1S/C18H41N3/c1-2-3-4-5-6-7-8-9-10-11-16-21(17-12-14-19)18-13-15-20/h2-20H2,1H3
InChIKey: NYNKJVPRTLBJNQ-UHFFFAOYSA-N
SMILES: C(N(CCCN)CCCCCCCCCCCC)CCN
LogP: 0.34 at 20℃
In fuel formulations, it helps prevent the buildup of deposits and microbial growth in diesel, gasoline, and aviation fuels.
Bis(3-aminopropyl)dodecylamine enhances the efficiency of engines by reducing wear, carbon buildup, and fuel degradation over time.
It is used in lubricants and greases to provide anti-corrosion, anti-wear, and oxidative stability properties.
Bis(3-aminopropyl)dodecylamine is used in epoxy resins, polyurethane coatings, and industrial adhesives, where it improves adhesion to metals, plastics, and composites.
It is a key ingredient in marine and automotive coatings, offering chemical resistance, durability, and anti-fouling properties.
While bis(3-aminopropyl)dodecylamine is highly effective in industrial and commercial applications, it can pose significant health, environmental, and chemical risks if not handled properly.
Bis(3-aminopropyl)dodecylamine is considered harmful to aquatic organisms, as it can cause toxic effects on fish, algae, and microorganisms.
If released into water sources, it may lead to long-term contamination and ecosystem disruption.
Spillage onto soil or industrial waste sites can result in persistent contamination, as the compound does not degrade easily.
Although not highly flammable, bis(3-aminopropyl)dodecylamine can decompose at high temperatures, releasing toxic nitrogen oxides (NOx) and other hazardous fumes.
It reacts with strong acids, oxidizing agents, and certain reactive chemicals, leading to heat generation and potential hazardous byproducts.
This alkylamine is contained in detergent-disinfectants solutions for medical instruments.
Bis(3-aminopropyl)dodecylamine is used in various industries due to its chemical stability, surface-active properties, and ability to protect materials from degradation. Some of the most common applications include:
One of its primary uses is as a corrosion inhibitor for metal pipelines, storage tanks, and drilling equipment.
It forms a protective molecular film on metal surfaces, preventing oxidation and rusting in harsh environments.
It is particularly useful in offshore drilling, petroleum refining, and natural gas extraction, where equipment is exposed to moisture, high salinity, and acidic gases like hydrogen sulfide (H₂S) and carbon dioxide (CO₂).
Due to its strong antibacterial and antifungal properties, bis(3-aminopropyl)dodecylamine is used in water treatment chemicals, industrial disinfectants, and fuel preservatives.
Bis(3-aminopropyl)dodecylamine helps prevent microbial contamination and biofilm formation in cooling systems, fuel storage tanks, and industrial processing equipment.
Bis(3-aminopropyl)dodecylamine is commonly included in paints, coatings, and adhesives to protect against mold, mildew, and bacterial degradation.
Its ability to interact with both hydrophobic and hydrophilic substances makes it useful as an emulsifier in detergents, cleaning agents, and oil-water separation systems.
Bis(3-aminopropyl)dodecylamine is found in metalworking fluids, textile softeners, and anti-static agents, where it improves the dispersion and stability of emulsions.
Use chemical-resistant gloves, safety goggles, and protective clothing to prevent skin and eye contact.
In environments with aerosol exposure, use respiratory protection such as N95 or chemical respirators.
Store in a cool, dry, well-ventilated area, away from heat, flames, and incompatible chemicals.
In case of spills, use absorbent materials and follow chemical waste disposal regulations.
Avoid disposing of large quantities in sewage systems, open water, or landfills.
Bis(3-aminopropyl)dodecylamine is a highly versatile industrial chemical with applications in corrosion inhibition, antimicrobial protection, fuel additives, and surfactant systems.
Its unique ability to interact with water, oil, and metal surfaces makes it an essential ingredient in many industrial and commercial formulations.
However, due to its irritant, toxic, and environmentally hazardous nature, strict handling, storage, and disposal guidelines must be followed to ensure safe usage.
When used responsibly, bis(3-aminopropyl)dodecylamine plays a crucial role in extending the lifespan of materials, enhancing fuel performance, and preventing microbial contamination in industrial settings.
Uses:
Bis(3-aminopropyl)dodecylamine is used as disinfectant for food processing industry, institutions, hospitals (surfaces and instruments)..
Bis(3-aminopropyl)dodecylamine is used as disinfectant for food processing industry, institutions, hospitals (surfaces and instruments).
Bis(3-aminopropyl)dodecylamine is a reactant used in the synthesis of gluconamide derivatives as cationic surfactants with antimicrobial properties.
Bis(3-aminopropyl)dodecylamine is used in the following products: biocides (e.g. disinfectants, pest control products), washing & cleaning products and lubricants and greases.
This substance is used for the manufacture of: .
Other release to the environment of Bis(3-aminopropyl)dodecylamine is likely to occur from: indoor use as processing aid and outdoor use as processing aid.
One of the most significant uses of bis(3-aminopropyl)dodecylamine is as a corrosion inhibitor in the oil and gas sector, where metal equipment is constantly exposed to moisture, acidic gases, saltwater, and extreme environmental conditions.
Bis(3-aminopropyl)dodecylamine functions by forming a protective molecular film over metal surfaces, preventing the oxidation, pitting, and rusting of pipelines, storage tanks, drilling tools, and offshore oil rigs.
The compound is highly effective in protecting carbon steel, stainless steel, and other alloys used in high-pressure gas extraction and crude oil refining.
It is commonly incorporated into pipeline cleaning solutions, wellbore treatments, and anti-corrosive coatings for extended durability in subsea and terrestrial applications.
Bis(3-aminopropyl)dodecylamine is an industrial-grade alkyl polyamine compound widely used across various sectors due to its surface-active properties, chemical stability, and ability to provide protection against corrosion, microbial contamination, and material degradation.
Its dual functionality—with both hydrophobic and hydrophilic components—makes it particularly useful in oil and gas, water treatment, lubricants, coatings, adhesives, and fuel additives. Below is a detailed breakdown of its primary applications:
Due to its strong antimicrobial properties, bis(3-aminopropyl)dodecylamine is frequently used as a biocidal additive in water treatment chemicals, cooling systems, and industrial disinfectants.
Bis(3-aminopropyl)dodecylamine is highly effective in preventing the growth of bacteria, algae, and fungi, which can lead to biofilm formation, fouling, and blockages in pipelines, heat exchangers, and cooling towers.
Bis(3-aminopropyl)dodecylamine is often incorporated into fuel biocides, where it helps prevent microbial contamination and spoilage in diesel, jet fuels, and marine fuels, especially in long-term storage tanks.
In addition to industrial applications, it is also used in medical disinfectants, preservatives for coatings and adhesives, and antimicrobial treatments for textiles and plastics.
Bis(3-aminopropyl)dodecylamine exhibits amphiphilic properties, meaning it has both hydrophilic (water-attracting) and hydrophobic (water-repelling) components.
This property makes it an excellent surfactant and emulsifier in numerous chemical formulations.
Bis(3-aminopropyl)dodecylamine is used in the production of industrial detergents, cleaning agents, and degreasers, particularly for heavy-duty cleaning in metalworking, automotive, and oil spill remediation applications.
Bis(3-aminopropyl)dodecylamine plays a key role in oil-water separation processes, helping break down and disperse oil residues in industrial wastewater treatment.
It is commonly included in lubricant formulations to improve dispersion, stability, and anti-wear properties for enhanced equipment longevity.
In the automotive, aviation, and marine industries, bis(3-aminopropyl)dodecylamine is frequently added to fuels to enhance engine performance, fuel stability, and longevity.
Bis(3-aminopropyl)dodecylamine works by preventing the formation of carbon deposits, varnish, and sludge in internal combustion engines, ensuring cleaner fuel combustion and improved efficiency.
The compound also acts as an anti-corrosion agent for fuel storage tanks and distribution systems, protecting them from water-induced rust and microbial degradation.
Bis(3-aminopropyl)dodecylamine is commonly used in diesel fuel stabilizers, jet fuel treatments, and marine fuel preservatives, where it helps maintain fuel purity and performance over extended storage periods.
Bis(3-aminopropyl)dodecylamine is widely used as an additive in industrial lubricants, greases, and metalworking fluids to enhance their anti-corrosion, anti-wear, and oxidative stability properties.
In high-temperature and high-friction environments, such as automotive engines, manufacturing equipment, and heavy machinery, it helps reduce metal-to-metal contact, minimizing wear and extending the lifespan of moving parts.
Bis(3-aminopropyl)dodecylamine is particularly useful in hydraulic fluids, compressor oils, and gear lubricants, where it prevents oil degradation and maintains viscosity stability over time.
The compound is used in the formulation of industrial adhesives, epoxy resins, polyurethane coatings, and protective sealants to improve adhesion, chemical resistance, and durability.
It enhances the binding properties of adhesives, making them more effective in bonding metals, plastics, and composite materials used in aerospace, automotive, and construction industries.
Bis(3-aminopropyl)dodecylamine is frequently incorporated into marine coatings, anti-corrosive paints, and chemical-resistant finishes, providing long-lasting protection against moisture, UV exposure, and harsh environmental conditions.
In the electronics and semiconductor industries, bis(3-aminopropyl)dodecylamine is used in specialized coatings to improve electrical insulation and resistance to humidity.
In the textile and leather industries, bis(3-aminopropyl)dodecylamine is used as a softener, anti-static agent, and finishing additive to improve fabric feel, durability, and water resistance.
Bis(3-aminopropyl)dodecylamine helps enhance dye penetration and fixation, making textiles more colorfast and resistant to washing or UV degradation.
In polymer processing, the compound is used as a stabilizer and dispersant, ensuring the uniform blending of plastic additives and improving the mechanical properties of final products.
Although not as common due to potential toxicity and skin irritation concerns, some formulations of cosmetic and personal care products may contain bis(3-aminopropyl)dodecylamine as a preservative or antimicrobial agent.
It has been used in specialty shampoos, hair conditioners, and antibacterial soaps, where it helps prevent microbial growth and extend product shelf life.
However, its use in consumer-facing products is highly regulated, and many manufacturers opt for safer, less irritating alternatives.
Bis(3-aminopropyl)dodecylamine is a highly versatile and chemically stable compound that plays a crucial role in multiple industrial sectors.
Its corrosion inhibition, antimicrobial protection, surface activity, and fuel-enhancing properties make it an indispensable ingredient in oil and gas production, lubricants, coatings, adhesives, and water treatment formulations.
However, due to its potential toxicity, environmental persistence, and chemical reactivity, proper handling, storage, and disposal measures are required to ensure safe and responsible use.
When applied appropriately, bis(3-aminopropyl)dodecylamine significantly enhances the performance, durability, and safety of industrial systems and products, making it a valuable asset in modern chemical engineering and manufacturing.
Safety Profile:
Bis(3-aminopropyl)dodecylamine is a highly reactive and potentially hazardous chemical that poses serious risks to human health, environmental safety, and material integrity if not handled properly.
Due to its strong alkaline nature, corrosive properties, and toxicity, exposure to this compound can result in severe skin and eye burns, respiratory irritation, environmental contamination, and long-term toxic effects.
Below is a detailed breakdown of the primary hazards associated with bis(3-aminopropyl)dodecylamine.
One of the most immediate hazards of bis(3-aminopropyl)dodecylamine is its highly corrosive nature, which can cause serious burns upon contact with skin and eyes.
Direct skin exposure to even small amounts of the chemical can lead to redness, blistering, ulceration, and deep tissue damage.
In severe cases, prolonged exposure may result in necrosis (tissue death), requiring extensive medical treatment.
Contact with the eyes is particularly dangerous, as it can cause severe conjunctivitis, corneal damage, and potentially permanent vision impairment.
In laboratory and industrial settings, it is mandatory to wear protective gloves, safety goggles, and chemical-resistant clothing to prevent accidental contact.
High-concentration exposure can lead to pulmonary edema, a condition in which fluid accumulates in the lungs, potentially resulting in severe breathing difficulties or chemical pneumonitis (lung inflammation caused by inhalation of toxic substances).
Accidental ingestion of bis(3-aminopropyl)dodecylamine is extremely dangerous and potentially fatal, as it can cause severe burns to the mouth, throat, esophagus, and stomach.
Bis(3-aminopropyl)dodecylamine is highly toxic to aquatic organisms, posing a serious threat to fish, invertebrates, and plant life when released into rivers, lakes, and oceans.
Bis(3-aminopropyl)dodecylamine has a tendency to accumulate in sediments and aquatic food chains, leading to long-term ecological damage and potential biomagnification (increased concentration in higher organisms, such as predatory fish and birds).
Even small concentrations can cause gill damage, respiratory distress, and mortality in fish and amphibians.
Industrial facilities that use or manufacture bis(3-aminopropyl)dodecylamine must strictly regulate wastewater disposal, prevent accidental spills, and comply with environmental regulations to minimize contamination risks.
