PRODUCTS

BIS(CYCLOHEXYL)AMINE

Bis(cyclohexyl)amine, belongs to the class of organic compounds known as cyclohexylamines.
Bis(cyclohexyl)amine is a secondary amine with the chemical formula HN(C6H11)2.
Bis(cyclohexyl)amine appears as a colorless liquid with a faint fishlike odor.

CAS Number: 101-83-7
EC Number: 202-980-7
Chemical Formula: (C6H11)2NH
Molar Mass: 181.32 g/mol

Synonyms: DICYCLOHEXYLAMINE, 101-83-7, N-Cyclohexylcyclohexanamine, Cyclohexanamine, N-cyclohexyl-, DCHA, Dicha, N,N-Dicyclohexylamine, Dodecahydrodiphenylamine, Dicyklohexylamin, N,N-Diclohexylamine, N-Cyclohexyl-cyclohexylamine, Dicyklohexylamin [Czech], NSC 3399, CCRIS 6228, HSDB 4018, EINECS 202-980-7, UN2565, UNII-1A93RJW924, BRN 0605923, MLS002174250, CHEBI:34694, AI3-15334, 1A93RJW924, NCGC00090955-03, SMR001224510, DCH, DTXSID6025018, NSC-3399, C12H23N, EC 202-980-7, 4-12-00-00022 (Beilstein Handbook Reference), DTXCID005018, CAS-101-83-7, dicydohexylamine, dicylohexylamine, dicylcohexylamine, Aminodicyclohexane, Cyclohexanamine, N -cyclohexyl-, di-cyclohexylamine, dicyclohexyl-amine, Dicyclohexyl amine, Sodium Cyclamate Imp. D (EP); N-Cyclohexylcyclohexanamine; Sodium Cyclamate Impurity D, bis-cyclohexylamine, Bis(cyclohexyl)amine, Cy2NH, Cyclohexylcyclohexanamine, Dicyclohexylamine, 99%, Dicyclohexylamine, 99+%, DSSTox_CID_5018, SCHEMBL500, cid_7582, DSSTox_RID_77630, NCIOpen2_002862, DSSTox_GSID_25018, Oprea1_024913, N,N-DICYCLOHXYL-AMINE, MLS002152900, BIDD:ER0258, DICYCLOHEXYLAMINE [MI], WLN: L6TJ AM-AL6TJ, Ciclohexanamina, N-ciclohexil-, DICYCLOHEXYLAMINE [HSDB], CHEMBL1451838, BDBM74256, NSC3399, HMS3741I15, STR04129, Tox21_111044, Tox21_201771, Tox21_303097, BBL002970, LS-340, MFCD00011658, NA2565, STK379549, Dicyclohexylamine, analytical standard, AKOS000119059, Tox21_111044_1, UN 2565, NCGC00090955-01, NCGC00090955-02, NCGC00090955-04, NCGC00090955-05, NCGC00090955-06, NCGC00257081-01, NCGC00259320-01, Dicyclohexylamine [UN2565] [Corrosive], Dicyclohexylamine Dodecahydro diphenylamine, Dicyclohexylamine [UN2565] [Corrosive], D0435, FT-0624742, EN300-17273, A11830, AG-617/02036022, Q425368, J-000503, F2190-0312, Sodium Cyclamate Imp. D (EP): N-Cyclohexylcyclohexanamine, DICYCLOHEXYLAMINE (SEE ALSO DICYCLOHEXYLAMINE NITRITE 3129-91-7), InChI=1/C12H23N/c1-3-7-11(8-4-1)13-12-9-5-2-6-10-12/h11-13H,1-10H, 101-83-7 [RN], 1A93RJW924, 202-980-7 [EINECS], Cyclohexanamine, N-cyclohexyl- [ACD/Index Name], Dicyclohexylamine [Wiki], HY4025000, MFCD00011658 [MDL number], N,N-DICYCLOHEXYLAMINE, N-Cyclohexylcyclohexanamin [German] [ACD/IUPAC Name], N-Cyclohexylcyclohexanamine [ACD/IUPAC Name], N-Cyclohexylcyclohexanamine [French] [ACD/IUPAC Name], 122-39-4 [RN], 4-12-00-00022 (Beilstein Handbook Reference) [Beilstein], Aminodicyclohexane, Bis(cyclohexyl)amine, Cyclohexylcyclohexanamine, DCH, DCHA, Dicha, Dicyclohexyl-amine, Dicyclohexylamine;Dodecahydro diphenylamine, dicyclohexylammonium, Dicyklohexylamin, Dodecahydro diphenylamine, Dodecahydrodiphenylamine, dodecahydrophenylamine, N, N-Dicyclohexylamine, N,N-Diclohexylamine, N,N-DICYCLOHXYL-AMINE, NCGC00090955-03, n-cyclohexanamine, N-Cyclohexyl-cyclohexylamine, Oprea1_024913, perhydrodiphenylamine, ST5207418, STR04129, UN 2565, UNII-1A93RJW924, WLN: L6TJ AM-AL6TJ

Bis(cyclohexyl)amine is a secondary amine with the chemical formula HN(C6H11)2.
Bis(cyclohexyl)amine is a colorless liquid, although commercial samples can appear yellow.

Bis(cyclohexyl)amine has a fishy odor, typical for amines.
Bis(cyclohexyl)amine is sparingly soluble in water.
As an amine, Bis(cyclohexyl)amine is an organic base and useful precursor to other chemicals.

Bis(cyclohexyl)amine appears as a colorless liquid with a faint fishlike odor.
Bis(cyclohexyl)amine is less dense than water.

Bis(cyclohexyl)amine is may be toxic by ingestion.
Bis(cyclohexyl)amine is severely irritates skin, eyes and mucous membranes.

Bis(cyclohexyl)amine is used to make paints, varnishes and detergents.
Bis(cyclohexyl)amine is a primary aliphatic amine.

Bis(cyclohexyl)amine is used as an intermediate for the production of antioxidants and vulcanization accelerator.
Bis(cyclohexyl)amine is used as a catalyst for flexible polyurethane foams.

Bis(cyclohexyl)amine is also used in agrochemicals and textile chemicals.
Bis(cyclohexyl)amine is used to constitute ionic liquid matrices for bacterial analysis in matrix assisted laser desorption/ionisation mass spectrometry.

Bis(cyclohexyl)amine is registered under the REACH Regulation and is manufactured in and / or imported to the European Economic Area, at ≥ 1 000 to < 10 000 tonnes per annum.
Bis(cyclohexyl)amine is used by professional workers (widespread uses), in formulation or re-packing, at industrial sites and in manufacturing.

Bis(cyclohexyl)amine with CAS No. 101-83-7 is an aliphatic amine.
As an intermediate, Bis(cyclohexyl)amine can be used in a broad range of applications in different industries.

One of the main uses is in the rubber industry where the Bis(cyclohexyl)amine is used as a vulcanization accelerator.
In lubricants and cutting fluids Bis(cyclohexyl)amine does function as a corrosion inhibitor.
Here Bis(cyclohexyl)amine should be mentioned that Bis(cyclohexyl)amine does not form Nitrosamines when being used.

Other applications of Bis(cyclohexyl)amine are in e.g dyes (as of dye precursor) or the use as a plasticizer.

Bis(cyclohexyl)amine has a fishy odor, typical for amines.
Bis(cyclohexyl)amine is sparingly soluble in water.

As an amine, Bis(cyclohexyl)amine is an organic base and a useful precursor to other chemicals.
Bis(cyclohexyl)amine can be used to make paints, varnishes and detergents.

Bis(cyclohexyl)amine is a primary aliphatic amine with chemical formula C12H23N.
Bis(cyclohexyl)amine appears as a colorless liquid with a faint fishlike odor.

Bis(cyclohexyl)amine is sparingly soluble in water.
As an amine, Bis(cyclohexyl)amine isan organic base and useful precursor to other chemicals.

Bis(cyclohexyl)amine , also known as dicyclohexylammonium, belongs to the class of organic compounds known as cyclohexylamines.
These are organic compounds containing a cyclohexylamine moiety, which consist of a cyclohexane ring attached to an amine group.

Bis(cyclohexyl)amine exists in all living organisms, ranging from bacteria to humans.
Based on a literature review a significant number of articles have been published on Bis(cyclohexyl)amine .

This compound has been identified in human blood as reported by (PMID: 31557052 ).
Bis(cyclohexyl)amine is not a naturally occurring metabolite and is only found in those individuals exposed to this compound or its derivatives.

Technically Bis(cyclohexyl)amine is part of the human exposome.
The exposome can be defined as the collection of all the exposures of an individual in a lifetime and how those exposures relate to health.
An individual's exposure begins before birth and includes insults from environmental and occupational sources.

Applications of Bis(cyclohexyl)amine:
Bis(cyclohexyl)amine is used especially for production of cure accelerator, lubricants and cutting fluids, for production of anticorrosion agents and in rubber industry.
Bis(cyclohexyl)amine is commercially important in manufacturing sulfenamides

Bis(cyclohexyl)amine is used as an intermediate for the production of antioxidants and vulcanization accelerator.
Bis(cyclohexyl)amine is used as a catalyst for flexible polyurethane foams.

Bis(cyclohexyl)amine was used to constitute ionic liquid matrices for bacterial analysis in matrix assisted laser desorption/ionisation mass spectrometry.
Bis(cyclohexyl)amine was used to develop a new palladium catalyst for Suzuki coupling reaction of aryl bromides with boronic acids.
Bis(cyclohexyl)amine was used as extractant in determination of gold(III) by dispersive liquid-liquid microextraction and electrothermal atomic absorption spectrometry.

Bis(cyclohexyl)amine has applications that are similar to those of cyclohexylamine, namely the production of:
Antioxidants in rubber and plastics
Vulcanization accelerators for rubber
Corrosion inhibitors in steam pipes and boilers
Agrochemicals
Textile chemicals
Catalysts for flexible polyurethane foams

Uses of Bis(cyclohexyl)amine:
Bis(cyclohexyl)amine is used to make drugs, soaps, detergents, vapor-phase corrosion inhibitors , dyestuffs, emulsifying agents, and acid gas absorbents.
Bis(cyclohexyl)amine is also used in insecticides and as a plasticizer, antioxidant (rubber, lubricating oils, and fuels), catalyst (paints, varnishes, and inks), and extractant (natural products).

Bis(cyclohexyl)amine can be commercially important in manufacturing sulfenamides.
Bis(cyclohexyl)amine is used as a chemical intermediate for the synthesis of dicyclohexylammonium nitrite; N,N-dicyclohexyl-2-benzothiazolesulphenamide; N-methylBis(cyclohexyl)amine

Widespread uses by professional workers:
Bis(cyclohexyl)amine is used in the following products: metal working fluids.
Bis(cyclohexyl)amine is used for the manufacture of: fabricated metal products and machinery and vehicles.
Other release to the environment of Bis(cyclohexyl)amine is likely to occur from: indoor use (e.g. machine wash liquids/detergents, automotive care products, paints and coating or adhesives, fragrances and air fresheners) and outdoor use as processing aid.

Uses at industrial sites:
Bis(cyclohexyl)amine is used in the following products: metal working fluids, heat transfer fluids, hydraulic fluids, lubricants and greases and polymers.
Bis(cyclohexyl)amine has an industrial use resulting in manufacture of another substance (use of intermediates).

Bis(cyclohexyl)amine is used in the following areas: formulation of mixtures and/or re-packaging.
Bis(cyclohexyl)amine is used for the manufacture of: chemicals, fabricated metal products and machinery and vehicles.
Release to the environment of Bis(cyclohexyl)amine can occur from industrial use: in processing aids at industrial sites, as an intermediate step in further manufacturing of another substance (use of intermediates), of substances in closed systems with minimal release and in the production of articles.

Industry Uses:
Absorbent
Adhesives and sealant chemicals
Corrosion inhibitor
Corrosion inhibitors and anti-scaling agents
Heat transferring agent
Intermediate
Lubricants and lubricant additives
Lubricating agent
Not Known or Reasonably Ascertainable
Plating agents and surface treating agents
Processing aids not otherwise specified
Solvents (for cleaning or degreasing)

Consumer Uses:
Adhesives and sealant chemicals
Corrosion inhibitor
Corrosion inhibitors and anti-scaling agents
Etching agent
Hardener
Intermediate
Lubricants and lubricant additives
Not Known or Reasonably Ascertainable
Solvents (for cleaning or degreasing)

Industrial Processes with risk of exposure:
Painting (Pigments, Binders, and Biocides)

Synthesis of Bis(cyclohexyl)amine:
Bis(cyclohexyl)amine, as a mixture with cyclohexylamine, is prepared by the catalytic hydrogenation of aniline (phenylamine), with a catalyst of ruthenium and/or palladium.
This method produces mainly cyclohexylamine with little Bis(cyclohexyl)amine.

Better results have been reported when the catalyst is applied to a support of niobic acid and/or tantalic acid.
Bis(cyclohexyl)amine is also obtained by reductive amination of cyclohexanone with ammonia or cyclohexylamine.

Bis(cyclohexyl)amine may also be prepared by pressure hydrogenation of diphenylamine using a ruthenium catalyst, or by the reaction of cyclohexanone with cyclohexylamine in the presence of a palladium/carbon catalyst under a hydrogen pressure of about 4 mm Hg.

Manufacturing Methods of Bis(cyclohexyl)amine:
Cyclohexanone + ammonia (reductive ammoniation; coproduced with cyclohexylamine)
Aniline is hydrogenated in the vapor phase over a nickel-on-pumice catalyst.

General Manufacturing Information of Bis(cyclohexyl)amine:

Industry Processing Sectors:
All Other Basic Organic Chemical Manufacturing
All Other Chemical Product and Preparation Manufacturing
Fabricated Metal Product Manufacturing
Not Known or Reasonably Ascertainable
Oil and Gas Drilling, Extraction, and Support activities
Petroleum Lubricating Oil and Grease Manufacturing
Primary Metal Manufacturing
Soap, Cleaning Compound, and Toilet Preparation Manufacturing
Transportation Equipment Manufacturing

Apperance of Bis(cyclohexyl)amine:
Bis(cyclohexyl)amine is a colorless liquid.
Bis(cyclohexyl)amine has a characteristic ammonical odor and tends to darken on standing.

Handling and Storage of Bis(cyclohexyl)amine:

Handling:
Avoid contact with skin, eyes, and clothing.
Do not breathe vapors, mists, or aerosols.

Use only in well-ventilated areas or under local exhaust.
Wear protective gloves, goggles, and suitable clothing.
Wash thoroughly after handling.

Storage:
Store in tightly closed containers in a cool, dry, and well-ventilated place.
Keep away from heat, sparks, open flames, and sources of ignition.

Store separately from strong oxidizers, acids, and halogenated compounds.
Protect from moisture.

Stability and Reactivity of Bis(cyclohexyl)amine:

Stability:
Stable under normal temperatures and pressures.

Reactivity:
Reacts with strong oxidizing agents and strong acids.
May attack certain plastics, rubber, or coatings.

Hazardous Decomposition Products:
On thermal decomposition or combustion, may release toxic fumes including carbon monoxide, carbon dioxide, and nitrogen oxides.

First Aid Measures of Bis(cyclohexyl)amine:

Inhalation:
Move the affected person to fresh air.
If breathing is difficult, administer oxygen.
Seek medical attention if symptoms persist.

Skin Contact:
Wash immediately with soap and plenty of water.
Remove contaminated clothing and shoes.
Seek medical advice if irritation develops.

Eye Contact:
Rinse cautiously with water for at least 15 minutes, lifting eyelids occasionally.
Remove contact lenses if present.
Seek immediate medical attention.

Ingestion:
Rinse mouth with water.
Do not induce vomiting.

Give water or milk to drink if conscious.
Seek medical attention immediately.

Firefighting Measures of Bis(cyclohexyl)amine:

Extinguishing Media:
Use dry chemical, foam, carbon dioxide, or water spray.

Hazards:
Combustible liquid and vapor.
Vapors may form explosive mixtures with air.
Burning may produce toxic nitrogen oxides and carbon oxides.

Protective Equipment:
Firefighters should wear self-contained breathing apparatus (SCBA) and full protective clothing.

Accidental Release Measures of Bis(cyclohexyl)amine:

Personal Precautions:
Wear suitable protective equipment (gloves, goggles, respirator if necessary).
Ensure adequate ventilation.

Remove all ignition sources.
Avoid inhalation of vapors and contact with skin/eyes.

Spill Cleanup:
Absorb with inert material (sand, earth, vermiculite).
Collect into suitable, labeled containers for disposal.

Wash contaminated area with soap and water after cleanup.
Prevent entry into drains, sewers, or waterways.

Exposure Controls / Personal Protection of Bis(cyclohexyl)amine:

Engineering Controls:
Provide local exhaust ventilation or general ventilation to maintain airborne concentrations below exposure limits.

Personal Protection:

Respiratory:
Use an approved respirator if ventilation is inadequate or if airborne concentrations exceed occupational limits.

Skin:
Wear chemical-resistant gloves (nitrile, neoprene, butyl rubber).

Eyes:
Use safety goggles or face shield.

Body:
Wear chemical-resistant clothing, apron, or lab coat.

Hygiene Measures:
Do not eat, drink, or smoke when handling the substance.
Wash hands, forearms, and face thoroughly after use.
Remove and wash contaminated clothing before reuse.

Identifiers of Bis(cyclohexyl)amine:
CAS Number: 101-83-7
ChemSpider: 7301
ECHA InfoCard: 100.002.710
EC Number: 202-980-7
PubChem CID: 7582
UNII: 1A93RJW924
CompTox Dashboard (EPA): DTXSID6025018
InChI: InChI=1S/C12H23N/c1-3-7-11(8-4-1)13-12-9-5-2-6-10-12/h11-13H,1-10H2
Key: XBPCUCUWBYBCDP-UHFFFAOYSA-N
SMILES: C1CCC(CC1)NC2CCCCC2

CAS number: 101-83-7
EC index number: 612-066-00-3
EC number: 202-980-7
Hill Formula: C₁₂H₂₃N
Chemical formula: (C₆H₁₁)₂NH
Molar Mass: 181.32 g/mol
HS Code: 2921 30 99

Linear Formula: (C6H11)2NH
CAS Number: 101-83-7
Molecular Weight: 181.32
Beilstein: 605923
EC Number: 202-980-7
MDL number: MFCD00011658
eCl@ss: 39030438
PubChem Substance ID: 24851183
NACRES: NA.22

CAS: 101-83-7
Molecular Formula: C12H23N
Molecular Weight (g/mol): 181.32
MDL Number: MFCD00011658
InChI Key: XBPCUCUWBYBCDP-UHFFFAOYSA-N
PubChem CID: 7582
ChEBI: CHEBI:34694
IUPAC Name: N-cyclohexylcyclohexanamine
SMILES: C1CCC(CC1)NC1CCCCC1

EC / List no.: 202-980-7
CAS no.: 101-83-7
Mol. formula: C12H23N

Product Number: D0435
Purity / Analysis Method: >99.0%(GC)
Molecular Formula / Molecular Weight: C12H23N = 181.32
Physical State (20 deg.C): Liquid
Store Under Inert Gas: Store under inert gas
Condition to Avoid: Air Sensitive
CAS RN: 101-83-7
Reaxys Registry Number: 605923
PubChem Substance ID: 87567113
SDBS (AIST Spectral DB): 2107
Merck Index (14): 3095
MDL Number: MFCD00011658

Properties of Bis(cyclohexyl)amine:
Chemical formula: C12H23N
Molar mass: 181.323 g·mol−1
Appearance: Pale yellow liquid
Density: 0.912 g/cm3
Melting point: −0.1 °C (31.8 °F; 273.0 K)
Boiling point: 255.8 °C (492.4 °F; 529.0 K)
Solubility in water: 0.8 g/L

vapor density: 6 (vs air)
Quality Level: 200
vapor pressure: 12 mmHg ( 37.7 °C)
Assay: 99%
form: liquid
refractive index: n20/D 1.484 (lit.)

bp:
117-120 °C/10 mmHg
256 °C (lit.)

mp: −2 °C (lit.)

solubility:
organic solvents: soluble
water: very slightly soluble

density: 0.912 g/mL at 20 °C (lit.)
SMILES string: C1CCC(CC1)NC2CCCCC2
InChI: 1S/C12H23N/c1-3-7-11(8-4-1)13-12-9-5-2-6-10-12/h11-13H,1-10H2
InChI key: XBPCUCUWBYBCDP-UHFFFAOYSA-N

Boiling point: 256 °C (1013 hPa)
Density: 0.91 g/cm3 (20 °C)
Explosion limit: 0.8 - 4.6 %(V)
Flash point: 96 °C
Ignition temperature: 240 °C
Melting Point: -0.1 °C
pH value: 11 (1 g/l, H₂O, 20 °C)
Vapor pressure: 16 hPa (37.7 °C)
Solubility: 1 g/l

Molecular Weight: 181.32 g/mol
XLogP3-AA: 3.4
Hydrogen Bond Donor Count: 1
Hydrogen Bond Acceptor Count: 1
Rotatable Bond Count: 2
Exact Mass: 181.183049738 g/mol
Monoisotopic Mass: 181.183049738 g/mol
Topological Polar Surface Area: 12Å²
Heavy Atom Count: 13
Complexity: 116
Isotope Atom Count: 0
Defined Atom Stereocenter Count: 0
Undefined Atom Stereocenter Count: 0
Defined Bond Stereocenter Count: 0
Undefined Bond Stereocenter Count: 0
Covalently-Bonded Unit Count: 1
Compound Is Canonicalized: Yes

Specifications of Bis(cyclohexyl)amine:
Assay (GC, area%): ≥ 99.0 % (a/a)
Density (d 20 °C/ 4 °C): 0.911 - 0.914
Water (K. F.): ≤ 0.30 %
Identity (IR): passes test

Melting Point: -2.0°C
Color: White
Density: 0.9100g/mL
Boiling Point: 256.0°C
Flash Point: 103°C
Infrared Spectrum: Authentic
Assay Percent Range: 99% min. (GC)
Packaging: Glass bottle
Linear Formula: (C6H11)2NH
Refractive Index: 1.4832 to 1.4852
Quantity: 5 mL
Beilstein: 12,6
Fieser: 01,231
Merck Index: 15,3106
Specific Gravity: 0.91
Solubility Information: Solubility in water: 0.8g/L (20°C).
Viscosity: 7.4 mPa.s (20°C)
Formula Weight: 181.32
Percent Purity: 99+%
Physical Form: Crystalline Powder
Chemical Name or Material: Bis(cyclohexyl)amine

Related Products of Bis(cyclohexyl)amine:
Tricine 7-Glucoside
N-5-Carboxypentyl-1-deoxynojirimycin
2-Acetamido-2-deoxy-D-gluconhydroximo-1,5-lactone 1,3,4,6-tetraacetate
O-(2-Acetamido-2-deoxy-3,4,6-tri-o-acetyl-D-glucopyranosylidene)amino N-(4-nitrophenyl)carbamate
N-5-Carboxypentyl-1-deoxygalactonojirimycin

Names of Bis(cyclohexyl)amine:

Regulatory process names:
Cyclohexanamine, N-cyclohexyl-
DCH
DCHA
Dicha
Dicyclohexylamine
DICYCLOHEXYLAMINE
Dicyclohexylamine
dicyclohexylamine
Dicyklohexylamin
Dodecahydrodiphenylamine
N,N-Diclohexylamine
N,N-Dicyclohexylamine
N-Cyclohexyl-cyclohexylamine

Translated names:
dicicloesilamina (it)
diciclohexilamina (es)
diciclohexilamina (pt)
diciclohexilamina (ro)
dicikloheksilamin (hr)
dicikloheksilamin (sl)
dicikloheksilaminas (lt)
dicikloheksilamīns (lv)
diciklohexil-amin (hu)
dicyclohexylamin (da)
Dicyclohexylamin (de)
dicyclohexylamine (fr)
dicyclohexylamine (nl)
dicykloheksylamin (no)
dicykloheksyloamina (pl)
dicyklohexylamin (cs)
dicyklohexylamin (sv)
dicyklohexylamín (sk)
disykloheksyyliamiini (fi)
Ditsükloheksüülamiin (et)
δικυκλοεξυλαμίνη (el)
дициклохексиламин (bg)

IUPAC names:
Dicyclohexylamine
dicyclohexylamine
dicyclohexylamine
dicyclohexylamine (DCHA)
dicyklohexylamin
N, N-Dicyclohexylamine
n-cyclohecylcyclohexanamine
N-cyclohexylcyclohexanamine

Preferred IUPAC name:
N-Cyclohexylcyclohexanamine

Trade names:
DCHA
dicyclohexylamine

Other identifiers:
101-83-7
111487-88-8
111487-93-5
111522-94-2
157973-63-2
612-066-00-3
856793-27-6
878781-89-6