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BIS (TRIMETHOXYSILYLPROPYL)AMINE

Bis (Trimethoxysilylpropyl)amine is a versatile organosilane used in various industrial applications due to its ability to bond with both organic and inorganic materials.
Bis (Trimethoxysilylpropyl)amine is an organosilane compound that contains both silane functional groups and an amine group, which makes it a versatile chemical used as a coupling agent, adhesion promoter, and surface modifier.
Bis (Trimethoxysilylpropyl)amine belongs to the family of organofunctional silanes, which are compounds designed to chemically bond organic materials, such as polymers, with inorganic surfaces like glass, metals, and minerals.

CAS Number: 82985-35-1
Molecular Formula: C12H31NO6Si2
Molecular Weight: 341.55
EINECS Number: 403-480-3

Synonyms:82985-35-1, Bis(trimethoxysilylpropyl)amine, DTXSID6033825, 6H96M8992G, DYNASYLAN 1124, 1-Propanamine, 3-(trimethoxysilyl)-N-[3-(trimethoxysilyl)propyl]-, SILQUEST A-1170, DTXCID4013825, 3-(Trimethoxysilyl)-N-(3-(trimethoxysilyl)propyl)propan-1-amine, 1-Propanamine, 3-(trimethoxysilyl)-N-(3-(trimethoxysilyl)propyl)-, J278.704K, 3-(trimethoxysilyl)-N-[3-(trimethoxysilyl)propyl]propan-1-amine, 280-084-5, 403-480-3, Bis(3-(trimethoxysilyl)propyl)amine, Bis[3-(trimethoxysilyl)propyl]amine, Organofunctional silane 45-49, 3,3'-Bis(trimethoxysilyl)dipropylamine, C12H31NO6Si2, 3-trimethoxysilyl-N-(3-trimethoxysilylpropyl)propan-1-amine, MFCD00191835, bis(3-trimethoxysilylpropyl)amine, EINECS 280-084-5, 3-(Trimethoxysilyl)-N-(3-(trimethoxysilyl)propyl)-1-propanamine, UNII-6H96M8992G, -N-(3-(Trimethoxysilyl, EC 280-084-5, SCHEMBL49693, SCHEMBL5350037, CHEMBL1392440, bis(3-trimethoxysilylpropyl) amine, Tox21_200368, Bis(Trimethoxysilylpropyl)Amine, 95%, AKOS015850837, NCGC00091039-01, NCGC00091039-02, NCGC00257922-01, AS-15381, BIS(3-TRIMETHOXYSILYLPROPYL)AMINE?, Bis(Trimethoxysilylpropyl)Amine Kh-1170, DA-35025, N,N-Bis-(3-(trimethoxysilyl)propyl)amine, CAS-82985-35-1, N,N-Bis-(3-(trimethoxysilyl)-propyl)amine, CS-0150970, N,N-Bis-(3-(trimethoxysilyl)-propyl) amine, BIS(.GAMMA.-TRIMETHOXYSILYLPROPYL)AMINE, H10681, S02260, EN300-7390740, N,N-BIS(3-(TRIMETHOXYSILYL)PROPYL)AMINE, 1-Propanamine, 3-(trimethoxysilyl)-N-[3-(trimethoxy, Q27264921, Bis[3-(trimethoxysilyl)propyl]amine, technical grade, >=90%, 3,3,11,11-tetramethoxy-2,12-dioxa-7-aza-3,11-disilatridecane., Bis[3-(trimethoxysilyl)propyl]amine,3,3′-Bis(trimethoxysilyl)dipropylamine, 3'-Bis(triMethoxysilyl)dipropylaMine, Iminobis(trimethylene)bis(trimethoxysilane), N,N-Bis(3-trimethoxysilylpropyl)amine, Bis[3-(triMethoxysilyl)propyl]aMine technical grade, >=90%, BIS(TRIMETHOXYSILYLPROPYL)AMINE, BIS[3-(TRIMETHOXYSILYL)PROPYL]AMINE, 3-(trimethoxysilyl)-n-(3-(trimethoxysilyl)propyl)-1-propanamine

Bis (Trimethoxysilylpropyl)amine is a bis-amino silane which can be used as a water based coupling agent that promotes the adhesion between different materials to form a hybrid material.
The amino groups in the polymer provide coating strength to the modified metal surfaces.
The silanol groups bond with the hydroxyls present on the surface of metals which are further cured to give metal-siloxane linkages.

Chemically, it is structured as a propylamine backbone that has two trimethoxysilyl groups attached, giving it the ability to hydrolyze in the presence of water to form silanol groups, which can then react with hydroxyl groups on surfaces such as silica, glass, or metal oxides.
At the same time, the amine functionality in its structure can react with organic resins, coatings, or adhesives, allowing it to act as a molecular bridge between organic and inorganic materials.

Because of these dual reactivity properties, Bis (Trimethoxysilylpropyl)amine is widely applied in composite materials, adhesives, sealants, coatings, and plastics where strong adhesion and durability are required.
Bis (Trimethoxysilylpropyl)amine is particularly useful in enhancing the compatibility between glass fibers and polymer matrices in fiberglass-reinforced composites, as well as in improving the water resistance and mechanical strength of coatings.

In industry, it is often marketed under trade names such as Bis (Trimethoxysilylpropyl)amine or Dynasylan 1124, and is valued for improving durability, corrosion resistance, and adhesion performance in end products.
Bis (Trimethoxysilylpropyl)amine is considered a multifunctional silane because it contains both an organofunctional group (the amine) and two hydrolyzable alkoxysilyl groups (the trimethoxysilyl groups).
This combination allows it to participate in a wide range of chemical reactions, giving it a very important role in materials science and industrial chemistry.

When it is exposed to moisture or water, the methoxy groups are hydrolyzed to form silanols, which can then condense with other silanols or react with hydroxylated surfaces.
This reaction forms stable siloxane bonds (Si–O–Si), which are known for their high strength and durability.
At the same time, the amine group can interact with a wide variety of organic systems, including epoxy, polyurethane, phenolic, and other resin types.

Because of these unique properties, Bis (Trimethoxysilylpropyl)amine is extensively used as a coupling agent in the production of glass fiber–reinforced plastics and composites.
In this role, it improves the interfacial bonding between inorganic glass fibers and organic polymer resins, which enhances mechanical strength, heat resistance, and long-term stability of the composite materials.
It is also commonly used as an adhesion promoter in paints, coatings, and sealants, where it significantly improves adhesion to metal, glass, and ceramic surfaces, while also providing resistance against water, weathering, and chemical attack.

Melting point : < 0 °C
Boiling point : 152 °C (4 mmHg, lit.)
Density : 1.04 g/mL at 25 °C (lit.)
Vapor pressure : 0–12790 Pa at 20–25 °C
Refractive index : n20/D 1.432 (lit.)
Flash point : > 230 °F
Storage temp. : 2–8 °C (protect from light)
Form : Clear liquid
pKa : 10.78 ± 0.19 (predicted)
Color : Colorless to light yellow to light orange
Specific gravity : 1.04
Viscosity : 5.7 mm²/s
Water solubility : 34–1000 g/L at 20 °C
Hydrolytic sensitivity : 7 (reacts slowly with moisture/water)
BRN : 9569446
InChIKey : TZZGHGKTHXIOMN-UHFFFAOYSA-N
LogP : –4 to –0.2 at 20 °C

In adhesives and sealants, this compound acts as a crosslinking agent that helps form strong, flexible bonds.
In plastics and rubbers, it improves compatibility between different phases, making the final material more uniform and stable.
In coatings, it not only enhances adhesion but also contributes to anti-corrosion properties, which is why it is valued in the automotive, aerospace, and construction industries.

Additionally, Bis(Trimethoxysilylpropyl)amine can be used in the formulation of primers, surface treatments, and hybrid organic–inorganic materials, giving it a very broad application spectrum.
Bis(Trimethoxysilylpropyl)amine is not just a simple silane derivative but a key performance additive that bridges the gap between organic and inorganic materials, making it essential in advanced materials engineering where durability, adhesion, and resistance to harsh environments are critical.

Bis (Trimethoxysilylpropyl)amine is often described as a bifunctional coupling agent because it is capable of reacting at two different chemical interfaces.
The trimethoxysilyl groups undergo hydrolysis in the presence of even small amounts of water or atmospheric humidity, forming silanol groups.
These silanols are highly reactive and bond covalently with hydroxyl groups on surfaces such as silica, alumina, glass, and various metal oxides.

This reaction results in a stable, tightly bound siloxane layer on the surface.
Meanwhile, the amine group of the molecule interacts chemically with reactive functional groups in organic resins, such as epoxides, isocyanates, and carboxylic groups.
This dual reactivity is what makes it such a powerful tool in bridging organic polymers with inorganic surfaces.

From a structural perspective, Bis (Trimethoxysilylpropyl)amine can be thought of as a molecular bridge-builder.
Without silane coupling agents like Bis (Trimethoxysilylpropyl)amine, the adhesion between hydrophilic inorganic fillers (like glass fibers) and hydrophobic organic polymers would often be weak and prone to separation under stress, moisture, or heat.

By creating strong covalent bonds at both interfaces, it dramatically increases mechanical strength, moisture resistance, and thermal stability of the final material.
For this reason, it is heavily used in the production of fiberglass-reinforced plastics (FRPs), rubber composites, high-performance coatings, and advanced sealants.

In addition, Bis(Trimethoxysilylpropyl)amine plays an important role in corrosion protection systems. When applied as a primer or as part of a surface treatment, it forms a siloxane network on metal substrates, which not only provides excellent adhesion for subsequent coatings but also serves as a barrier layer that reduces the diffusion of water, oxygen, and corrosive agents to the metal surface.
This property has made it a valuable ingredient in automotive primers, aerospace coatings, marine paints, and construction materials where long-term resistance to rust and environmental degradation is essential.

Another important field is hybrid organic–inorganic materials.
Researchers and industries use Bis (Trimethoxysilylpropyl)amine in sol-gel chemistry and nanocomposite production, where its silane groups help form inorganic networks while its amine group participates in organic crosslinking reactions.
This versatility makes it an attractive choice for developing functional coatings, specialty polymers, and advanced composites with tailored performance properties.

Uses Of Bis (Trimethoxysilylpropyl)amine:
BTMSPA and Bis (Trimethoxysilylpropyl)amine can be used to synthesize an amine modified mesostructured organosilica for potential applications in catalysis and absorbance.
Metal finishing may be deviced by coating BTMSPA and vinyltriacetoxysilane which can be used for protection against corrosion.

Bis (Trimethoxysilylpropyl)amine is used in method for dyeing keratinous material, comprising the use of an organosilicon compound, an effect pigment and a film-forming polymer.
Bis (Trimethoxysilylpropyl)amine has a wide range of uses, and these are directly connected to its unique chemical structure, which combines both silane and amine functional groups.

This dual functionality allows the compound to serve as a coupling agent, adhesion promoter, and surface modifier in many industrial applications.
One of its most important uses is in the manufacture of fiberglass-reinforced plastics and composites.
In these systems, the silane portion of the molecule forms stable chemical bonds with the glass fiber surface, while the amine portion reacts with the polymer matrix, such as epoxy, polyurethane, or phenolic resins.

This dual bonding action results in stronger interfacial adhesion, which significantly improves the mechanical strength, durability, heat resistance, and moisture resistance of the final composite product.
For this reason, Bis(Trimethoxysilylpropyl)amine is widely used in the automotive, aerospace, marine, and construction industries where lightweight, high-strength composite materials are required.
Bis (Trimethoxysilylpropyl)amine is also heavily used as an adhesion promoter in coatings, sealants, and adhesives.

When incorporated into these formulations, the compound ensures that the coating or adhesive sticks more effectively to difficult surfaces such as glass, metal, or ceramics.
This results in improved bond strength, longer service life, and better resistance against peeling, cracking, or delamination, even under harsh environmental conditions. For example, in automotive coatings, it enhances paint adhesion to metal substrates and contributes to superior corrosion resistance, while in sealants it ensures long-lasting flexibility and bonding power.

Another important use is in the production of corrosion-resistant primers and surface treatments.
Bis (Trimethoxysilylpropyl)amine forms a thin, chemically bonded siloxane network on metal surfaces, which not only improves adhesion for subsequent paint layers but also serves as a protective barrier against oxygen, water, and salt.
This makes it particularly valuable in marine coatings, aerospace coatings, and industrial paints, where metals are frequently exposed to corrosive environments.

In addition to coatings and composites, the compound is used in the rubber and plastic industries as a coupling agent and crosslinking aid.
It helps improve the dispersion of inorganic fillers like silica into rubber and plastic matrices, which enhances mechanical performance, elasticity, and resistance to wear and tear.
This is especially important in applications such as tires, seals, gaskets, and molded plastic parts.

Bis(Trimethoxysilylpropyl)amine also finds applications in electronics and semiconductor materials, where it is used as a surface modifier to improve adhesion between silicon wafers, glass substrates, and organic polymer layers.
Its ability to create strong, uniform chemical bonds helps ensure the reliability, stability, and longevity of electronic components.

Furthermore, it is used in sol-gel processes and hybrid organic–inorganic material development, where it serves as a reactive silane building block.
In these systems, the silane groups form part of the inorganic network, while the amine group participates in organic polymerization reactions, allowing researchers and manufacturers to design advanced coatings, functional films, and nanocomposites with tailored properties.

Bis (Trimethoxysilylpropyl)amine are not limited to a single sector but extend across multiple industries.
Whether in construction, automotive, aerospace, marine, electronics, or materials research, it plays a critical role in enhancing adhesion, durability, strength, and resistance to environmental stress, making it a highly valuable specialty chemical in modern manufacturing.

Safety Profile Of Bis (Trimethoxysilylpropyl)amine:
Bis(Trimethoxysilylpropyl)amine, like many organosilanes, is a functional and useful compound, but it is also associated with several health, safety, and environmental hazards that need to be carefully considered when it is manufactured, transported, stored, or used in industrial settings.
Although its risks can vary depending on the concentration, purity, and exposure conditions, it is generally handled as a substance that poses irritant, toxic, and environmentally hazardous properties.

From a health perspective, one of the main hazards of Bis(Trimethoxysilylpropyl)amine is that it can cause serious irritation to the skin, eyes, and respiratory tract.
Direct skin contact may lead to redness, dryness, or chemical burns if the exposure is prolonged or repeated.

Contact with the eyes can result in pain, severe irritation, and even long-term damage if not treated immediately.
Inhalation of vapors, dust, or aerosols containing this substance can irritate the nose, throat, and lungs, leading to coughing, shortness of breath, and discomfort.
At higher concentrations or in poorly ventilated areas, it may cause more severe respiratory distress.

Accidental ingestion, although less likely in an industrial setting, can cause gastrointestinal irritation, nausea, abdominal pain, and potential systemic effects.
Another hazard is related to its reactivity with water and moisture.

Bis(Trimethoxysilylpropyl)amine contains methoxy groups that readily hydrolyze in the presence of water or even atmospheric humidity, producing methanol as a by-product.
Methanol is a highly toxic and flammable substance that can cause headache, dizziness, nausea, and, in cases of significant exposure, blindness or central nervous system damage.
This means that workers handling the chemical are at risk not only from direct contact with the silane itself but also from secondary exposure to methanol vapors generated during hydrolysis.