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Blanose carboxymethylcellulose (CMC) is a sodium salt derivative of cellulose, specifically a carboxymethyl ether of cellulose.
Blanose carboxymethylcellulose (CMC) is a widely used polymer known for its thickening, stabilizing, emulsifying, and binding properties.
Blanose carboxymethylcellulose (CMC) often refers to a specific brand or grade of CMC produced by various manufacturers, but in general, CMC refers to the same base chemical compound.
CAS Number: 9004-32-4
Molecular Formula: C6H7O2(OH)2CH2COONa
EINECS Number: 618-378-6
Synonyms: 9004-32-4, SODIUM CARBOXYMETHYL CELLULOSE, sodium;2,3,4,5,6-pentahydroxyhexanal;acetate, Carboxymethylcellulose sodium (USP), Carboxymethylcellulose cellulose carboxymethyl ether, Celluvisc (TN), Carmellose sodium (JP18), CHEMBL242021, SCHEMBL25311455
C.M.C. (TN), CHEBI:31357, Sodium carboxymethyl cellulose (MW 250000), D01544, M.W. 700000(DS=0.9) ,2500 - 4500mPa.sAquacide I, Calbiochem, Aquacide II, Calbiochem, Carboxyl Methyl Cellulose sodium, Cellex, Cellulose carboxymethyl ether, sodium, cellulose gum, SODIUM CARBOXY METHYL CELLULOSE (CMC),SCMC(SODIUM CARBOXY METHYL CELULLOSE.
Blanose carboxymethylcellulose (CMC) are anionic, water-soluble cellulose ethers, produced by reacting alkali cellulose with monochloroacetic acid under controlled conditions.
A variety of grades with different degrees of substitution, viscosities and particle sizes to meet specific formulation requirements are available.
Blanose carboxymethylcellulose (CMC) is a water-soluble polymer. As a solution in water, it has thixotropic properties.
Blanose carboxymethylcellulose (CMC) is useful in helping to hold the components of pyrotechnic compositions in aqucous suspension (e.g., in the making of black match).
It is also an especially effective binder that can be used in small amounts in compositions, where the binder can intcrfere with the intended effect (e.g., in strobe compositions).
However, its sodium content obviously precludes its use in most color compositions.
Blanose carboxymethylcellulose (CMC) is manufactured from cellulose by various proseses that replacc some of the hydrogen atoms in the hydroxyl[OH] groups of the cellulose molecule with acidic carboxymethyl [-CH2CO.OH] groups，which are neutralized to form the corresponding sodium salt.
Blanose carboxymethylcellulose (CMC) is white when pure; industrial grade material may be grayish-white or cream granules or powder.
Blanose carboxymethylcellulose (CMC), or cellulose gum is widely used as a thickener and stabilizer in foods and beverages, having the ability to form strong, oil-resistant films.
Besides modifying the behavior of water, cellulose gum is useful in suspending solids and modifying the flow and texture.
Blanose carboxymethylcellulose (CMC) has a substitution range of: 0,65 to 0,90, a viscosity of 2500-4500 (mPa*s), a concentration of 1 %, and a spindle number of 4. RPM: 30. The fine particle size version of Blanose 7H4F.
Blanose carboxymethylcellulose (CMC) is an anionic water-soluble polymer that is widely used in toothpastes as a thickener to bind water for the prevention of syneresis and impart desirable flow properties appearance totoothpaste formulations.
In addition to toothpaste formulations, cellulose gum is also used in denture adhesive creams and powders to provide hold.
Blanose carboxymethylcellulose (CMC) is available in wide variety of grades to meet formulation needs.
Blanose carboxymethylcellulose (CMC) is derivatized from natural, renewable resources.
Blanose carboxymethylcellulose (CMC) is made by reacting sodium monochloroacetate with alkali cellulose under rigidly controlled conditions.
The resultant anionic polymer is purified and dried.
Blanose carboxymethylcellulose (CMC) is an anionic, water-soluble polymer.
Blanose carboxymethylcellulose (CMC) are anionic, water-soluble cellulose ethers, produced by reacting alkalicellulose with monochloroacetic acid under controlled conditions.
Blanose carboxymethylcellulose (CMC) is available in a variety of grades with different degrees of substitution, viscosity and particle size to meet specific formulation requirements are available.
Ashland provides CMC under the tradenames Blanose carboxymethylcellulose (CMC) depending on site of manufacture.
Blanose carboxymethylcellulose (CMC) is tackifier, at room temperature, it is non-toxic tasteless white flocculent powder, it is stable and soluble in water, aqueous solution is neutral or alkaline transparent viscous liquid, it is soluble in other water-soluble gums and resins, it is insoluble in organic solvents such as ethanol.
Blanose carboxymethylcellulose (CMC) is the substituted product of cellulosic carboxymethyl group.
According to their molecular weight or degree of substitution, it can be completely dissolved or insoluble polymer, the latter can be used as the weak acid cation of exchanger to separate neutral or basic proteins.
Blanose carboxymethylcellulose (CMC) can form highly viscous colloidal solution with adhesive, thickening, flowing, emulsifying, shaping, water, protective colloid, film forming, acid, salt, suspensions and other characteristics, and it is physiologically harmless, so it is widely used in the food, pharmaceutical, cosmetic, oil, paper, textiles, construction and other areas of production.
Blanose carboxymethylcellulose (CMC) are anionic, water-soluble polymers.
Blanose carboxymethylcellulose (CMC) is made by reacting alkali cellulose with sodium monochloroacetate under rigidly controlled conditions.
The resultant polymer is purified and dried.
Blanose carboxymethylcellulose (CMC) for personal care and cosmetic applications is typically sold at 99.5 percent minimum purity.
Physical and solution properties of Blanose carboxymethylcellulose (CMC) can be varied through manipulation of degree of substitution (DS) and molecular weight.
Blanose carboxymethylcellulose (CMC) is typically offered in three different DS ranges and a broad range of molecular weights.
A variety of Blanose carboxymethylcellulose (CMC) grades are available to meet formulation needs.
Blanose carboxymethylcellulose (CMC) is a water-soluble sodium salt of carboxymethylcellulose. Used for rheology control and water retention of coating colours, in offset printing, water-based paints, and seed coating.
Blanose carboxymethylcellulose (CMC) can also be used as a binder, stabilizer, protective colloid, and film former.
Blanose carboxymethylcellulose (CMC) acts as a thickener.
It is an anionic polymer made by reacting sodium monochloroacetate with alkalicellulose under rigidly controlled conditions.
Blanose carboxymethylcellulose (CMC) is used for water binding and syneresis control.
Blanose carboxymethylcellulose (CMC) has the ability to suspend pigments and active ingredients in solution.
Blanose carboxymethylcellulose (CMC) is used in oral care and skin care applications.
Blanose carboxymethylcellulose (CMC) is made by reacting sodium monochloroacetate with alkalicellulose under rigidly controlled conditions.
The resultant anionic polymer is purified and dried.
Blanose carboxymethylcellulose (CMC) is highly soluble in cold and hot water, forming a clear, viscous solution.
It can dissolve in both neutral and slightly alkaline conditions, making it versatile for various applications.
The viscosity of CMC can vary depending on the specific grade.
Blanose carboxymethylcellulose (CMC) comes in different viscosity grades, allowing users to select the appropriate one for their application needs.
Blanose carboxymethylcellulose (CMC) is derived from natural cellulose, making it non-toxic and environmentally friendly.
Blanose carboxymethylcellulose (CMC) is stable over a wide pH range, typically from 3 to 11, which allows for its use in various formulations without degradation.
Blanose carboxymethylcellulose (CMC) maintains its properties even when subjected to heat, making it suitable for applications that involve processing at high temperatures.
Blanose carboxymethylcellulose (CMC) has a wide range of applications across several industries:
Used to enhance the texture of sauces, gravies, soups, salad dressings, and other food products.
Helps stabilize emulsions (mixtures of oil and water) in products like mayonnaise and ice cream, preventing separation.
Acts as a fat replacer in low-fat and reduced-calorie products, providing a creamy mouthfeel.
Improves the mouthfeel and consistency of gluten-free products, enhancing their quality and performance.
Keeps solid particles evenly dispersed in liquid formulations, such as syrups and suspensions.
Blanose carboxymethylcellulose (CMC) acts as a binder in tablet formulations, helping to hold ingredients together and improve tablet strength.
In formulations designed for controlled release, Blanose carboxymethylcellulose (CMC) can help regulate the release of active pharmaceutical ingredients (APIs).
Blanose carboxymethylcellulose (CMC) is used in lotions, creams, shampoos, and other personal care products to achieve the desired viscosity.
Helps prevent the separation of oil and water phases in creams and lotions, ensuring a stable product.
Contributes to skin hydration in cosmetic formulations.
Acts as a rheology modifier in water-based paints and coatings, improving viscosity and preventing sagging or dripping during application.
Blanose carboxymethylcellulose (CMC) is used as a thickener in adhesives and sealants to ensure even application and strong adhesion.
Blanose carboxymethylcellulose (CMC) is used as a thickener in printing pastes to achieve precise patterns and improve print quality.
Functions as a binder in paper coatings, enhancing smoothness and printability.
Melting point: 274 °C (dec.)
Density: 1,6 g/cm3
FEMA: 2239 | CARBOXYMETHYLCELLULOSE
storage temp.: room temp
solubility: H2O: 20 mg/mL, soluble
form: low viscosity
pka: 4.30(at 25℃)
color: White to light yellow
Odor: Odorless
PH Range: 6.5 - 8.5
PH: pH (10g/l, 25℃) 6.0～8.0
Viscosity: 900 to 1400 mPa-s(1 %, H2O, 25 ℃)
Water Solubility: soluble
Merck: 14,1829
Blanose carboxymethylcellulose (CMC) is made by reactingsodium monochloroacetate with alkalicellulose under rigidly controlledconditions.
The resultant anionic polymer is purified and dried.
Purified Blanose carboxymethylcellulose (CMC) for personal care and cosmetic applications is typically sold at 99.5 percent minimum purity.
In addition to thick eningaqueous systems, CMC is used in personal care products for water binding, syneresis control and its ability to suspend pigments and active ingredients insolution.
Blanose carboxymethylcellulose (CMC) is an anionic, water-soluble polymer.
A variety of Blanose carboxymethylcellulose (CMC) grades are available, with varying degrees of substitution, viscosities andparticle sizes.
Sodium carboxymethyl cellulose is formed when cellulose reacts with mono chloroacetic acid or its sodium salt under alkaline condition with presence of organic solvent, hydroxyl groups substituted by Sodium carboxymethyl groups in C2, C3 and C6 of glucose, which substitution slightly prevails at C2 position.
Generally, there are two steps in manufacturing process of sodium carboxymethyl cellulose, alkalinization and etherification.
Use warm water or cold water when preparing the solution, and stir till it completely melts.
The amount of added water depends on variety and the use of multiple requirements.
High viscosity Blanose carboxymethylcellulose (CMC) is a white or slightly yellow fibrous powder, hygroscopic, odorless, tasteless, non-toxic, easy to ferment, insoluble in acids, alcohols and organic solvents, easily dispersed to form colloidal solution in water.
Blanose carboxymethylcellulose (CMC) is reacted by the acid and fibrous cotton, it is mainly used for water-based drilling fluids tackifier, it has certain role of fluid loss, it has strong salt and temperature resistance especially.
Blanose carboxymethylcellulose (CMC) is the sodium salt of carboxymethyl cellulose, an anionic derivative.
It is widely used in oral and topical pharmaceutical formulations, primarily for its viscosity-increasing properties.
Viscous aqueous solutions are used to suspend powders intended for either topical application or oral and parenteral administration.
Blanose carboxymethylcellulose (CMC) may also be used as a tablet binder and disintegrant, and to stabilize emulsions.
Higher concentrations, usually 3–6%, of the medium-viscosity grade are used to produce gels that can be used as the base for applications and pastes; glycols are often included in such gels to prevent them drying out.
Blanose carboxymethylcellulose (CMC) is also used in self-adhesive ostomy, wound care, and dermatological patches as a muco-adhesive and to absorb wound exudate or transepidermal water and sweat.
This muco-adhesive property is used in products designed to prevent post-surgical tissue adhesions; and to localize and modify the release kinetics of active ingredients applied to mucous membranes; and for bone repair.
Encapsulation with Blanose carboxymethylcellulose (CMC) can affect drug protection and delivery.
There have also been reports of its use as a cyto-protective agent.
Blanose carboxymethylcellulose (CMC) is also used in cosmetics, toiletries, surgical prosthetics, and incontinence, personal hygiene, and food products.
Storage:
Blanose carboxymethylcellulose (CMC) is a stable, though hygroscopic material.
Under high-humidity conditions, Blanose carboxymethylcellulose (CMC) can absorb a large quantity (>50%) of water.
In tablets, this has been associated with a decrease in tablet hardness and an increase in disintegration time.
Aqueous solutions are stable at pH 2–10; precipitation can occur below pH 2, and solution viscosity decreases rapidly above pH 10.
Generally, solutions exhibit maximum viscosity and stability at pH 7–9.
Blanose carboxymethylcellulose (CMC) may be sterilized in the dry state by maintaining it at a temperature of 1608℃ for 1 hour.
However, this process results in a significant decrease in viscosity and some deterioration in the properties of solutions prepared from the sterilized material.
Aqueous solutions may similarly be sterilized by heating, although this also results in some reduction in viscosity.
After autoclaving, viscosity is reduced by about 25%, but this reduction is less marked than for solutions prepared from material sterilized in the dry state.
The extent of the reduction is dependent on the molecular weight and degree of substitution; higher molecular weight grades generally undergo a greater percentage reduction in viscosity. Sterilization of solutions by gamma irradiation also results in a reduction in viscosity.
Aqueous solutions stored for prolonged periods should contain an antimicrobial preservative.
Uses:
Blanose carboxymethylcellulose (CMC) is frequently called simply carboxymethyl cellulose and also known as cellulose gum.
It is derived from purified cellulose from cotton and wood pulp.
Blanose carboxymethylcellulose (CMC) is a water dispersible sodium salt of carboxy-methyl ether of cellulose that forms a clear colloidal solution.
Blanose carboxymethylcellulose (CMC) is a hygroscopic material that has the ability to absorb more than 50% of water at high humidity.
It is also a natural polymeric derivative that can be used in detergents, food and textile industries.
Blanose carboxymethylcellulose (CMC) is one of the most important products of cellulose ethers, which are formed by natural cellulose modification as a kind of cellulose derivate with an ether structure.
Due to the fact that the acid form of Blanose carboxymethylcellulose (CMC) has poor water solubility, it is usually preserved as sodium carboxymethylcellulose, which is widely used in many industries and regarded as monosodium glutamate in industry.
Blanose carboxymethylcellulose (CMC) is used in cigarette adhesive, fabric sizing, footwear paste meal, home slimy.
Blanose carboxymethylcellulose (CMC) is used in interior painting architectural, building lines melamine, thickening mortar, concrete enhancement.
Blanose carboxymethylcellulose (CMC) is used in refractory fiber, ceramic production molding bond.
Blanose carboxymethylcellulose (CMC) is used in oil drilling, exploration address slurry thickening, reducing water loss, quality paper surface sizing.
It can be used as soap and washing powder detergent active additives, as well as other industrial production on the dispersion, emulsification, stability, suspension, film, paper, polishing and the like. Quality product can be used for toothpaste, medicine, food and other industrial sectors.
Blanose carboxymethylcellulose (CMC) is a thickener, binder, and emulsifier equivalent to cellulose fiber.
It is resistant to bacterial decomposition and provides a product with uniform viscosity.
It can prevent skin moisture loss by forming a film on the skin’s surface, and also help mask odor in a cosmetic product.
Blanose carboxymethylcellulose (CMC)s are any of several fibrous substances consisting of the chief part of a plant’s cell walls (often extracted from wood pulp or cotton).
In drilling muds, in detergents as a soil-suspending agent, in resin emulsion paints, adhesives, printing inks, textile sizes, as protective colloid in general.
As stabilizer in foods. Pharmaceutic aid (suspending agent; tablet excipient; viscosity-increasing agent).
Blanose carboxymethylcellulose (CMC) is used in drilling muds, in detergents as a soil-suspending agent, in resin emulsion paints, adhesives, printing inks, textile sizes and protective colloid.
It acts as a stabilizer in foods.
It is also employed in pharmaceuticals as a suspending agent and excipients for tablets.
Blanose carboxymethylcellulose (CMC) is used as viscosity modifiers to stabilize the emulsions.
Blanose carboxymethylcellulose (CMC) is used as a lubricant in artificial tears and it is used to characterize enzyme activity from endoglucanases.
Blanose carboxymethylcellulose (CMC) is used in sauces, gravies, soups, salad dressings, and beverages to enhance viscosity and texture.
Prevents separation of ingredients in emulsified products like mayonnaise and ice cream, ensuring a uniform consistency.
Acts as a fat replacer in low-fat and reduced-calorie food products, providing a creamy mouthfeel without added calories.
Improves the texture and quality of gluten-free baked goods, enhancing moisture retention and overall mouthfeel.
Blanose carboxymethylcellulose (CMC) is used in fruit juices and beverages to keep pulp and other solid ingredients evenly dispersed.
Keeps solid particles uniformly suspended in liquid formulations, such as syrups and oral suspensions.
Functions as a binder in tablet formulations, ensuring cohesive properties and mechanical strength.
Blanose carboxymethylcellulose (CMC) is used in formulations designed for controlled or sustained release of active pharmaceutical ingredients (APIs).
In tablet coatings, it provides a smooth and protective layer around the tablet.
Employed in lotions, creams, shampoos, and conditioners to achieve desired viscosity and texture.
Blanose carboxymethylcellulose (CMC) helps maintain the stability of emulsions in cosmetics, preventing oil and water separation.
Retains moisture on the skin, enhancing hydration and improving skin feel in cosmetic products.
Blanose carboxymethylcellulose (CMC) is used in hair gels and styling products to create a flexible, non-sticky film.
Acts as a rheology modifier in water-based paints, improving viscosity and preventing sagging or dripping during application.
Blanose carboxymethylcellulose (CMC) is used as a thickener in adhesives and sealants to ensure even application and enhance bonding strength.
Serves as a thickener in textile printing pastes, ensuring precision in printing and improved quality of designs.
Blanose carboxymethylcellulose (CMC) is used in printing pastes to achieve sharp, clear patterns while maintaining consistency during application.
Functions as a binder in paper and board coatings, enhancing smoothness, printability, and overall finish.
Blanose carboxymethylcellulose (CMC) is used in drilling fluids to improve viscosity and stabilize the fluid, enhancing drilling efficiency.
In some formulations, Blanose carboxymethylcellulose (CMC) can act as a soil conditioner or stabilizer for slow-release fertilizers.
Safety Profile:
Blanose carboxymethylcellulose (CMC) is used in oral, topical, and some parenteral formulations.
It is also widely used in cosmetics, toiletries, and food products, and is generally regarded as a nontoxic and nonirritant material.
However, oral consumption of large amounts of carboxymethylcellulose sodium can have a laxative effect; therapeutically, 4–10 g in daily divided doses of the medium- and high-viscosity grades of carboxymethylcellulose sodium have been used as bulk laxatives.
Mildly toxic by ingestion.
Blanose carboxymethylcellulose (CMC) experimental reproductive effects.
Questionable carcinogen with experimental neoplastigenic data.
Blanose carboxymethylcellulose (CMC) migrates to food from packagmg materials.
When heated to decomposition it emits toxic fumes of NazO.
The WHO has not specified an acceptable daily intake for Blanose carboxymethylcellulose (CMC) as a food additive since the levels necessary to achieve a desired effect were not considered to be a hazard to health.
However, in animal studies, subcutaneous administration of Blanose carboxymethylcellulose (CMC) has been found to cause inflammation, and in some cases of repeated injection fibrosarcomas have been found at the site of injection.
Hypersensitivity and anaphylactic reactions have occurred in cattle and horses, which have been attributed to Blanose carboxymethylcellulose (CMC) in parenteral formulations such as vaccines and penicillins.
