BLOCKED METHANE SULPHONIC ACID

Blocked methane sulphonic acid is widely used in the pharmaceutical industry.
Blocked methane sulphonic acid is employed in various industries due to its strong acidity and favorable properties.
Blocked methane sulphonic acid is used as an electrolyte in electroplating processes for metals like tin and lead.

CAS Number: 75-75-2
EC Number: 200-898-6
MDL Number: MFCD00007518
Molecular Formula: CH₄O₃S
Molecular Weight: 96.11 g/mol

SYNONYMS:
MsOH, MSA, MeSO₃H, Methylsulfonic acid, Methanesulphonic acid, Sulfomethane, Mesylic acid, Methanesulfonate, Methansulfonsäure, Kyselina methansulfonova, Methanesulfonic acid, Methylsulfonic acid, MSA, Mesylic acid, Methane sulfonic acid, MSA, methylsulfonic acid, mesilic acid, Methanesulfonic acid, Methanesulphonic acid, Mesylate, Methylsulfonate, Methane sulfonic acid, MSA, methanesulfonic acid mesylates kyselina methansulfonova iron (3+)salt methanesulfonic acid methanesulfonic acid, silver (1+) salt methanesulfonic acid, iron (3+)salt nickel (2+) salt methanesulfonic acid silver (1+) salt methanesulfonic acid MSA sodium salt methanesulfonic acid,

Blocked methane sulphonic acid, also known as methanesulphonic acid, is a strong, colorless, and hygroscopic organic acid with the molecular formula CH₄O₃S.
Blocked methane sulphonic acid or methanesulphonic acid (in British English) is an organosulfuric, colorless liquid with the molecular formula CH3SO3H and structure H3C−S(=O)2−OH.

Blocked methane sulphonic acid is the simplest of the alkylsulfonic acids (R−S(=O)2−OH).
Salts and esters of Blocked methane sulphonic acid are known as mesylates (or methanesulfonates, as in ethyl methanesulfonate).
Blocked methane sulphonic acid is hygroscopic in its concentrated form.

Blocked methane sulphonic acid can dissolve a wide range of metal salts, many of them in significantly higher concentrations than in hydrochloric acid (HCl) or sulfuric acid (H2SO4).
Blocked methane sulphonic acid is a strong organic acid which is highly suitable for manufacturing active pharmaceutical ingredients such as 

Telmisartan and Eprosartan, Angiotensin II receptor antagonists.
Blocked methane sulphonic acid is a colorless liquid with the chemical formula CH3SO3H.
Blocked methane sulphonic acid is the simplest of the alkylsulfonic acids.

Salts and esters of methanesulfonic acid are known as mesylates.
Blocked methane sulphonic acid is hygroscopic in its concentrated form.
Blocked methane sulphonic acid is a strong organic acid.

The chemical oxidation of dimethyl sulfide in the atmosphere leads to the formation of Blocked methane sulphonic acid in large quantities.
Blocked methane sulphonic acid undergoes biodegradation by forming CO2 and sulphate.
It is considered a green acid as Blocked methane sulphonic acid is less toxic and corrosive in comparison to mineral acids.

Blocked methane sulphonic acid is a clear liquid that can be colourless, pale yellow or pale brown.
Blocked methane sulphonic acid has low endotoxin making it suitable for parenteral applications.
Blocked methane sulphonic acid, also known as methanesulfonic acid or mesylic acid.

Blocked methane sulphonic acid is a colorless liquid with the chemical formula CH₃SO₃H.
Blocked methane sulphonic acid is the simplest of the alkylsulfonic acids.

Salts and esters of methanesulfonic acid are known as mesylates (or methanesulfonates, as in ethyl methanesulfonate).
Blocked methane sulphonic acid is hygroscopic in its concentrated form.

USES and APPLICATIONS of BLOCKED METHANE SULPHONIC ACID:
Blocked methane sulphonic acid is used as solvent, catalyst of alkylation, esterification and polymerization.
Blocked methane sulphonic acid is widely used in the pharmaceutical industry.
Blocked methane sulphonic acid is employed in various industries due to its strong acidity and favorable properties.

Electroplating:  Blocked methane sulphonic acid is used as an electrolyte in electroplating processes for metals like tin and lead.
Organic Synthesis: Blocked methane sulphonic acid acts as a catalyst in esterification and alkylation reactions.
Pharmaceuticals: Blocked methane sulphonic acid serves as a counterion in the formation of mesylate salts of active pharmaceutical ingredients.

Cleaning Agents: Blocked methane sulphonic acid is utilized in formulations for cleaning and descaling due to its effectiveness in removing mineral deposits.
Polymerization: Blocked methane sulphonic acid functions as a catalyst in polymerization reactions.

Blocked methane sulphonic acid is the simplest alkylsulfonic acid and is widely utilized in various industrial and laboratory applications.
Solutions of Blocked methane sulphonic acid are used for the electroplating of tin and tin-lead solders.
Blocked methane sulphonic acid is displacing the use of fluoroboric acid, which releases corrosive and volatile hydrogen fluoride.

Blocked methane sulphonic acid is also a primary ingredient in rust and scale removers.
Blocked methane sulphonic acid is used to clean off surface rust from ceramic, tiles and porcelain which are usually susceptible to acid attack.

Blocked methane sulphonic acid is widely used in the pharmaceutical industry.
Blocked methane sulphonic acid is used Buffering agents, pH Modifier, Stabilizing agent, and Intermediate in preparation of API.
Blocked methane sulphonic acid is a clear colourless to pale yellow, pale brown or pale brownish yellow clear liquid

Blocked methane sulphonic acid is an organic sulfuric acid, a colorless liquid with the molecular formula CH3SO3H.
The salts and esters of Blocked methane sulphonic acid are called mesylates (or methanesulfonates, as in ethyl methanesulfonate).
In its concentrated form, Blocked methane sulphonic acid is hygroscopic.

Blocked methane sulphonic acid is capable of dissolving a wide range of metal salts, many of which are in much higher concentrations than hydrochloric acid (HCl) or sulfuric acid (H2SO4).

Blocked methane sulphonic acid has become a popular substitute for other acids in many industrial and laboratory applications because it:
*is a strong acid,
*has a low vapor pressure (does not evaporate, e.g. like nitric or hydrochloric acids)
*is not oxidizing or explosive like nitric, sulfuric or perchloric acids
*is a liquid at room temperature,
*soluble in most organic solvents,
*forms water-soluble salts with all inorganic cations and most organic cations,
*does not form complexes with metal ions in water,
*its anion, mesylate, is non-toxic and suitable for pharmaceutical preparations

The closest analogue, p-toluenesulfonic acid (PTSA), is solid
used in detergents because Blocked methane sulphonic acid does not cause eutrophication in water bodies
In the electroplating industry, Blocked methane sulphonic acid solutions are used to electroplate tin and tin-lead alloys.

Blocked methane sulphonic acid displaces fluoroboric acid, which releases corrosive and volatile hydrogen fluoride.
Blocked methane sulphonic acid is used as an electrolyte in electroplating processes such as nickel plating, copper plating and tin plating.
Blocked methane sulphonic acid acts as a buffer to maintain the pH of the electrolyte solution and to help ensure uniform coverage of the metal substrate.

In the cleaning industry, Blocked methane sulphonic acid is a key ingredient in rust and plaque removers from acid-sensitive surfaces.
Blocked methane sulphonic acid is used to clean rust from ceramics, tiles and porcelain, which are generally sensitive to strong acids.

Blocked methane sulphonic acid is an excellent alternative to traditional phosphoric acid-based rust removers/cleaners as it is not inferior in cleaning performance and does not contribute to eutrophication (water damage) when discharged into wastewater.
This property is particularly relevant for operators of individual sewage treatment plants, as Blocked methane sulphonic acid does not impair their operation and does not damage the water bodies into which the treated wastewater is discharged.

In the chemical industry, Blocked methane sulphonic acid is a substance for the formation of secondary methane sulfonates from olefins, a chemical for the production of trifluoromethanesulfonic acid, and for the production of methane sulfonyl chloride.
Catalyst in esterification, alkylation, olefin polymerization, peroxidation reactions.

Blocked methane sulphonic acid has many uses in the pharmaceutical industry including as a buffering agent, pH modifier and stabilising agent.
Blocked methane sulphonic acid is also used as an intermediate in the preparation of APIs.
In electrical engineering, Blocked methane sulphonic acid is used to etch pressed electrical panels.

Blocked methane sulphonic acid is used as an alternative to inorganic acids because it not only performs its function well but also does not corrode the metals of the plates.
This prolongs the service life of the plates.

Use as a solvent: Blocked methane sulphonic acid is not only an excellent catalyst for the chitin acylation process but also a good solvent for partially acylated chitin.
Therefore, homogeneous chitin acylation can be achieved in the Blocked methane sulphonic acid system.

Blocked methane sulphonic acid is used as a solvent for high molecular weight polymers.
In water systems, Blocked methane sulphonic acid is used for regeneration of water softening filter charges.
Blocked methane sulphonic acid is well suited because it does not damage anion exchange and cation exchange resins and reacts well with the metals on their surface, thus opening the active centres of the resins and allowing the charges to operate at full capacity.

In the electrical industry, Blocked methane sulphonic acid is used to dissolve lead salts to produce the electrolyte in bipolar batteries.
Blocked methane sulphonic acid has the advantage of eliminating the parasitic reactions that inhibit the storage/generation of chemical electricity, greatly simplifying the battery design, and allowing the production of energy storage/batteries in a wide range of sizes.

In metals processing and extraction, Blocked methane sulphonic acid is of particular interest in lead hydrometallurgy, where it is a greener alternative to HBF₄ and H₂SiF₆.
However, Blocked methane sulphonic acid can also be used in all hydrometallurgical processes that require strong Brønsted acids.

Blocked methane sulphonic acid can be used in copper, zinc, cobalt, nickel and rare earth metallurgy, as well as in the recycling of metals from discarded products.
The high solubility of methanesulfonate salts compared to sulphate and chloride salts is also useful for the recovery of Blocked methane sulphonic acid in process solutions after removal of precious metals.

For example, if CaO, Ca(OH)₂ or CaCO₃ is used to neutralize excess Blocked methane sulphonic acid after leaching, and the metals have been removed from the saturated leach solution by precipitation as hydroxides or sulfides, there will be a significant amount of dissolved calcium methanesulfonate in the raffinate.

The addition of sulfuric acid to this solution results in the precipitation of CaSO₄·2H₂O (gypsum) and the Blocked methane sulphonic acid is recovered and can be reused.
Similarly, silver can be recovered from MSA salt solutions by adding hydrochloric acid.

This produces a sparingly soluble silver(I) chloride which precipitates out.
Rare earth elements (REE) can be recovered from MSA solutions by the addition of oxalic acid.
In order to develop a new MSA-based process for the refining of recycled raw silver from secondary resources, the characteristics of silver metal pellet dissolution in Blocked methane sulphonic acid were investigated.

Although Blocked methane sulphonic acid alone did not dissolve the pellets, they were dissolved by the addition of hydrogen peroxide as an oxidant.
Silver pellets containing about 94 % silver together with other precious metals such as gold and PGMs were successfully dissolved with a mixture of Blocked methane sulphonic acid and hydrogen peroxide.

The extraction yields were found to be in excess of 90 %, with solid-liquid ratios of up to 550 g/L and a stoichiometric excess of hydrogen peroxide of three times.
The optimum yield was found to be between 65 °C and 85 °C.

A high selectivity for palladium was achieved: only 7 % of palladium dissolved together.
The dissolution residue consisted mainly of gold and undissolved silver, with small amounts of palladium and platinum.
A negative correlation was observed between the solubility of silver(I) methanesulphonate and the concentration of free Blocked methane sulphonic acid after leaching.

Blocked methane sulphonic acid has been shown to be an effective solvent for dissolving the cathode material of LiCoO₂ lithium ion batteries.
With a small amount of hydrogen peroxide as a reducing agent (0.9 % by volume), lithium and cobalt could be leached very efficiently with a 1 M Blocked methane sulphonic acid solution.

Blocked methane sulphonic acid performed much better than the other organic acids tested (citric acid, malonic acid, succinic acid and oxalic acid).
Dissolved cobalt precipitated as CoCO₃ and was calcined to Co₃O₄, while dissolved lithium precipitated as Li₂CO₃ with the addition of Na₂CO₃ solution.

Li₂CO₃ and Co₃O₄ were combined in a solid state to form the new cathode material LiCoO₂.
Blocked methane sulphonic acid is used virtually in all electronic applications involving tin or tin-alloy plating from non-fluoborate systems.
Blocked methane sulphonic acid replaces phosphoric acid in detergent formulations, thereby helping to avoid environmental phosphate pollution.

Blocked methane sulphonic acid is used in the preparation of polyaniline/graphene nanocomposites, which enhances its thermal and electrical properties.
Blocked methane sulphonic acid is utilized for electropolishing of aluminum as well as in electroplating of noble metals like gold, platinum, palladium and their alloys.

As a catalyst, Blocked methane sulphonic acid reduces corrosion of stainless steel equipment while ensuring efficient conversion processes.
Blocked methane sulphonic acid also allows the use of cheaper feedstocks such as agricultural waste, used cooking oil, waste cooking oils, thus increasing the economic viability of biodiesel production.

Blocked methane sulphonic acid plays an important role in making biofuels more sustainable and economically viable.
Blocked methane sulphonic acid is widely used as an acid catalyst and solvent in organic reactions in biological and agricultural industry.
Blocked methane sulphonic acid is also a key ingredient in plating various metals to print circuit board manufacture in electric industry.

Besides, Blocked methane sulphonic acid is popularly used in textile treatment, and the production of plastics and polymers.
Blocked methane sulphonic acid is used as an acid catalyst in organic reactions because it is a non-volatile, strong acid that is soluble in organic solvents.

Blocked methane sulphonic acid is used virtually in all electronic applications involving tin or tin-alloy plating from non-fluoborate systems.
Blocked methane sulphonic acid replaces phosphoric acid in detergent formulations, thereby helping to avoid environmental phosphate pollution.
Blocked methane sulphonic acid is used in the preparation of polyaniline/graphene nanocomposites, which enhances its thermal and electrical properties.

Blocked methane sulphonic acid is utilized for electropolishing of aluminum as well as in electroplating of noble metals like gold, platinum, palladium and their alloys.

Key applications of Blocked methane sulphonic acid: Plastics and polymers, Fabric, textile and leather products, Corrosion inhibitor and anti-scaling agent, Metal finishing, Agricultural, Catalysts, Solvents, Pharmaceuticals, Batteries, Building & Construction products, and Electronics.

Blocked methane sulphonic acid is particularly effective for catalyzing esterification and polymerization reactions.
Blocked methane sulphonic acid is also employed as a catalyst in condensation, cyclization, alkylation and rearrangement reactions.

Apart from being used as a catalyst, Blocked methane sulphonic acid is also employed as a feedstock in the manufacture of salts (the methanesulfonates).
Blocked methane sulphonic acid is used as a solvent to improve yields in various processes.

-Blocked methane sulphonic acid is used in oil industry (well stimulation):
Blocked methane sulphonic acid is used in the oilfield industry for acidification treatments that increase production by dissolving mineral deposits and improving reservoir permeability.
Blocked methane sulphonic acid acts as a catalyst to break down complex hydrocarbons and increase oil recovery efficiency.

Blocked methane sulphonic acid has lower corrosion and biodegradability, resulting in reduced equipment corrosion and longer service life, and lower maintenance costs.
In addition, the biodegradable properties of Blocked methane sulphonic acid contribute to environmentally friendly oilfield operations.

INDUSTRIAL PRODUCTION OF BLOCKED METHANE SULPHONIC ACID:
The first commercial production of Blocked methane sulphonic acid, developed in the 1940s by Standard Oil of Indiana, was based on oxidation of dimethylsulfide by O₂ from air.
Although inexpensive, this process suffered from a poor product quality and explosion hazards.

Starting from the 1960s, it received a shortened name of mesylic acid after the term for the "mesyl" group coined by Helferich et al. in 1938.
In 1967, the Pennwalt Corporation (USA) developed a different process for dimethylsulfide (as a water-based emulsion) oxidation using chlorine, followed by extraction-purification.

In 2022 this chlorine-oxidation process was used only by Arkema (France) for making high-purity Blocked methane sulphonic acid.
This process is not popular on a large scale, because it co-produces large quantities of hydrochloric acid.

Between years 1970 and 2000 Blocked methane sulphonic acid was used only on a relatively small-scale in niche markets (for example, in the microelectronic and electroplating industries since the 1980s), which was mainly due to its rather high price and limited availability.

However, this situation changed around 2003, when BASF launched commercial production of Blocked methane sulphonic acid in Ludwigshafen based on a modified version of the aforementioned air oxidation process, oxidising dimethyldisulfide with nitric acid which is then restored using atmospheric oxygen.

The former is produced in one step from methanol from syngas, hydrogen and sulfur.
An even better (lower-cost and environmentally friendlier) process of making Blocked methane sulphonic acid was developed in 2016 by Grillo-Werke AG (Germany).

It is based on a direct reaction between methane and oleum at around 50 °C and 100 bar in the presence of a potassium persulfate initiator.
Further addition of sulfur trioxide gives methanedisulfonic acid instead.
This technology was acquired and commercialized by BASF in 2019.

Blocked methane sulphonic acid can be used in the generation of borane (BH₃) by reacting methanesulfonic acid with NaBH₄ in an aprotic solvent such as THF or DMSO, the complex of BH₃ and the solvent is formed.
In pharmaceuticals, Blocked methane sulphonic acid is very suitable for the production of active pharmaceutical ingredients such as telmisartan and eprosartan, angiotensin II receptor antagonists.

Blocked methane sulphonic acid plays an important role in a wide range of pharmaceutical applications, from the synthesis of active pharmaceutical ingredients (APIs) to drug formulation.
As a catalyst, Blocked methane sulphonic acid facilitates key reactions in the synthesis of APIs such as esterification, acylation and sulfonation.

Blocked methane sulphonic acid's efficiency in promoting these reactions allows the efficient production of pharmaceutical intermediates and final APIs.
Blocked methane sulphonic acid is also used in drug formulation processes where it helps to solubilize and stabilize active compounds.

Blocked methane sulphonic acid's compatibility with various solvents and its mild nature contribute to the development of safe and effective pharmaceutical formulations.
In the chemical industry, Blocked methane sulphonic acid is a very important catalyst in the chemical industry, especially in esterification processes.

Its strong acidic properties allow the efficient and selective formation of esters from carboxylic acids and alcohols.
Blocked methane sulphonic acid's versatility and compatibility with a wide range of substrates make it a very important component in the synthesis of pharmaceuticals, flavorings, fragrances and specialty chemicals.

Blocked methane sulphonic acid's non-oxidizing properties, which prevent the formation of by-products and discoloration, make it more selective than other strong acids such as nitric or sulfuric acids.

In the biodiesel industry, Blocked methane sulphonic acid covers key steps throughout the production chain, from the esterification catalyst to reduce the free fatty acid content before transesterification, to the neutralization to improve glycerol and ester quality.
Blocked methane sulphonic acid in biodiesel production offers the dual benefits of reducing corrosion and using cost-effective feedstock.

SUSTAINABLE ALTERNATIVE TO CONVENTIONAL ACIDS:
Blocked methane sulphonic acid is a strong organic acid used in numerous applications ranging from chemical and biofuel synthesis to industrial cleaning and metal surface treatment in the electronics industry.
The expansion is in line with the trend for top-performance and at the same time environmentally friendly technologies in various industries.

Blocked methane sulphonic acid is a sustainable alternative to other acids such as sulfuric, phosphoric or acetic acid.
As part of the natural sulfur cycle Blocked methane sulphonic acid is readily biodegradable.

Further benefits in practical applications come, for example, from Blocked methane sulphonic acid's nonoxidizing nature, the high solubility of its salts and the absence of color and odor.

INDUSTRIES OF BLOCKED METHANE SULPHONIC ACID:
*Polymers
*Energy Services
*Cleaning
*CASE & Construction
*Beauty & Personal Care

✅ BENEFITS AND CHARACTERISTICS OF BLOCKED METHANE SULPHONIC ACID:
*Strong Acid: 
Comparable in strength to mineral acids like sulfuric acid.

*Non-Volatile: 
Low vapor pressure reduces inhalation risks.

*Biodegradable: 
Blocked methane sulphonic acid breaks down into non-toxic components, making it environmentally friendly.

*Non-Oxidizing: 
Blocked methane sulphonic acid does not introduce oxidative stress in reactions.

*Metal Compatibility: 
Less corrosive to metals compared to other strong acids.

SOLUBILITY OF BLOCKED METHANE SULPHONIC ACID:
Blocked methane sulphonic acid is miscible with water.
Blocked methane sulphonic acid is slightly miscible with benzene and toluene.
Blocked methane sulphonic acid is immiscible with paraffins.

NOTES OF BLOCKED METHANE SULPHONIC ACID:
Blocked methane sulphonic acid has Light and heat sensitive.
Keep Blocked methane sulphonic acid the container tightly closed in a dry and well-ventilated place.
Blocked methane sulphonic acid is incompatible with amines, strong reducing agents, ethyl vinyl ether, hydrofluoric acid, strong oxidizing agents and bases.

HISTORY AND SYNTHESIS OF BLOCKED METHANE SULPHONIC ACID:
Early history
German chemist Hermann Kolbe discovered MSA between 1842 and 1845 and originally termed it methyl hyposulphuric acid.

The discovery stemmed from earlier work by Berzelius and Marcet in 1813, who treated carbon disulfide with moist chlorine and produced a compound they named "sulphite of chloride of carbon".
By reacting it with barium hydroxide Kolbe demonstrated it to actually be trichloromethylsulfonyl chloride (CCl₃SO₂Cl in modern notation).
2 CCl3SO2Cl + 3 Ba(OH)2 → Ba(CCl3SO3)2 + 3 BaCl2 + 2 H2O

From resulting barium trichloromethylsulfonate Kolbe isolated the free acid, which he was then able to sequentially dechlorinate by electrolytically generated atomic hydrogen to ultimately yield MSA.
CCl3SO3H + 3 H → CHCl2SO3H + 2 H + HCl → … → CH3SO3H + 3 HCl

Kolbe's research on methanesulfonic and chloroacetic acids was hailed by Berzelius as strong evidence for his theory of copulated compounds, a modification of radical theory to accommodate substitution reactions which posited the combination of organic and inorganic moieties without significantly altering the properties of the latter.

Later in the 19th century, the name transitioned to methyl sulphonic acid.
Other historical laboratory synthesis routes included oxidizing methanethiol, dimethyl disulfide or methyl thiocyanate with nitric acid.

ADVANTAGES OF BLOCKED METHANE SULPHONIC ACID:
*Strong, odor-free organic acid
*Non-oxidizing
*Virtually free of metal ions and sulfate
*Manufacturing process makes the product free of chlorine and colorless.
*Easy to handle in liquid form
*Strong acid prevents the formation of oxidation products.
*Reactions at higher temperatures possible
*The excellent solubility in water enables easy phase separations.
*Decomposes to form sulfate, carbon dioxide, water and biomass

PHYSICAL and CHEMICAL PROPERTIES of BLOCKED METHANE SULPHONIC ACID:
CAS Number: 75-75-2
EC Index Number: 607-145-00-4
EC Number: 200-898-6
Hill Formula: CH₄O₃S
Chemical Formula: CH₃SO₃H
Molar Mass: 96.11 g/mol
HS Code: 2904 10 11
Boiling Point: 167 °C (13 hPa)
Density: 1.4812 g/cm³ (18 °C)

Flash Point: 189 °C
Melting Point: 20 °C
pH Value: <1 (H₂O, 20 °C)
Vapor Pressure: 0.112 hPa (80 °C)
Solubility: 1000 g/l
Physical State: Liquid
Color: Colorlesslight brown
Odor: No data available
Melting Point/Freezing Point

Melting Point/Range: -60 °C
Initial Boiling Point and Boiling Range: No data available
Flammability (Solid, Gas): No data available
Upper/Lower Flammability or Explosive Limits: No data available
Flash Point: Not applicable
Autoignition Temperature: No data available
Decomposition Temperature: No data available
pH: 0 - 1
Viscosity
Viscosity, Kinematic: No data available
Viscosity, Dynamic: No data available

Water Solubility: No data available
Partition Coefficient: n-Octanol/Water
log Pow: -4.98
Vapor Pressure: No data available
Density: 1.345 - 1.360 g/cm³ at 20 °C
Relative Density: No data available
Relative Vapor Density: No data available
Particle Characteristics: No data available
Explosive Properties: Not classified as explosive.
Oxidizing Properties: None
Other Safety Information: No data available

CAS: 75-75-2
Molar Mass: 96.10 g/mol
Density: 1.35 g/cm³
Solubility: Miscible
Boiling Point/Range: No data available
Color: Colorless
Corrosivity: Corrosive to metals
Density: 1.039 g/cm³ (20 °C)
Flashpoint: Not applicable
Form: Liquid
Grade: HPLC Grade

Incompatible Materials: Corrosive in contact with metals, Bases
Lower Explosion Limit: Not applicable
Melting Point/Range: No data available
Solubility in Water: Soluble
Upper Explosion Limit: Not applicable
Storage Temperature: Ambient
Molar Weight: 96.10 g/mol
Melting Point: 17-19 °C
Boiling Point: 167 °C

Flash Point: >110 °C
Density: 1.35 g/cc
Forms: Liquid (clear), Colorless
Form: Liquid
Appearance (Color): Clear colorless
Assay (Aqueous Acid-Base Titration): ≥68.5 to ≤71.5%
CAS: 75-75-2
IUPAC Name: Methanesulfonic acid
Molecular Formula: CH₄O₃S
InChI Key: AFVFQIVMOAPDHO-UHFFFAOYSA-N

SMILES: CS(O)(=O)=O
Molecular Weight (g/mol): 96.10
CAS Number: 75-75-2
EC Number: 200-898-6
Molecular Formula: CH₄O₃S
Molecular Weight: 96.11 g/mol
IUPAC Name: Methanesulfonic acid
PubChem CID: 6395
SMILES: CS(=O)(=O)O
InChI Key: AFVFQIVMOAPDHO-UHFFFAOYSA-N

Appearance: Colorless liquid
Odor: Characteristic
Density: 1.481 g/cm³
Melting Point: 19 °C
Boiling Point: 167 °C at 13 hPa
Flash Point: 156 °C
pKa: −1.9 (strong acid)
Solubility: Miscible with water, ethanol, tetrahydrofuran, 
and dimethyl sulfoxide; limited solubility in toluene and n-hexane

Chemical Formula: CH₄O₃S
Molar Mass: 96.10 g·mol⁻¹
Appearance: Clear, colourless liquid
Density: 1.48 g/cm³
Melting Point: 17 to 19 °C (63 to 66 °F; 290 to 292 K)
Boiling Point: 167 °C (333 °F; 440 K) at 10 mmHg, 122 °C/1 mmHg
Solubility in Water: Miscible
Solubility: Miscible with methanol, diethyl ether.
Immiscible with: Hexane
log P: −2.424[1]
Acidity (pKa): −1.9

Molecular Formula / Molecular Weight: CH₄O₃S = 96.10
Physical State (20 °C): Liquid
Storage Temperature: Room Temperature (Recommended in a cool and dark place, <15 °C)
Store Under Inert Gas: Store under inert gas
Condition to Avoid: Hygroscopic
CAS RN: 75-75-2
Reaxys Registry Number: 1446024
PubChem Substance ID: 87572203
SDBS (AIST Spectral DB): 4261
Merck Index (14): 5954
MDL Number:
MFCD Number: MFCD00007518

FIRST AID MEASURES of BLOCKED METHANE SULPHONIC ACID:
-Description of first-aid measures
*General advice:
Show this material safety data sheet to the doctor in attendance.
*If inhaled:
After inhalation: 
Fresh air.
*In case of skin contact: 
Take off immediately all contaminated clothing. 
Rinse skin with
water/ shower.
*In case of eye contact:
After eye contact: 
Rinse out with plenty of water. 
Call in ophthalmologist. 
Remove contact lenses.
*If swallowed:
After swallowing: 
Immediately make victim drink water (two glasses at most). 
Consult a physician.
-Indication of any immediate medical attention and special treatment needed.
No data available

ACCIDENTAL RELEASE MEASURES of BLOCKED METHANE SULPHONIC ACID:
-Environmental precautions:
Do not let product enter drains.
-Methods and materials for containment and cleaning up:
Cover drains. 
Collect, bind, and pump off spills. 
Observe possible material restrictions. 
Take up dry. 
Dispose of properly. 
Clean up affected area.

FIRE FIGHTING MEASURES of BLOCKED METHANE SULPHONIC ACID:
-Extinguishing media:
*Suitable extinguishing media:
Carbon dioxide (CO2) 
Foam 
Dry powder
*Unsuitable extinguishing media:
For this substance/mixture no limitations of extinguishing agents are given.
-Further information:
Prevent fire extinguishing water from contaminating surface water or the ground water system.

EXPOSURE CONTROLS/PERSONAL PROTECTION of BLOCKED METHANE SULPHONIC ACID:
-Control parameters:
--Ingredients with workplace control parameters:
-Exposure controls:
--Personal protective equipment:
*Eye/face protection:
Use equipment for eye protection. 
Safety glasses
*Body Protection:
protective clothing
*Respiratory protection:
Recommended Filter type: Filter A 
-Control of environmental exposure:
Do not let product enter drains.

HANDLING and STORAGE of BLOCKED METHANE SULPHONIC ACID:
-Conditions for safe storage, including any incompatibilities:
*Storage conditions:
Tightly closed. 
Dry.

STABILITY and REACTIVITY of BLOCKED METHANE SULPHONIC ACID:
-Chemical stability:
The product is chemically stable under standard ambient conditions (room temperature).
-Possibility of hazardous reactions:
No data available