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CAS Number : 107-88-0
EC Number : 203-529-7
ECHA InfoCard : 100.003.209
PubChem CID : 7896
ChemSpider : 7608
Chemical formula : C4H10O2
Molar mass : 90.122 g·mol−1
Density : 1.0053 g cm−3
Melting point : −50 °C
Preferred IUPAC name :
Butane-1,3-diol
Other names :
1,3-butylene glycol, butane-1,3-diol, or 1,3-dihydroxybutane
1,3-Butanediol
Butane-1,3-diol is an organic compound with the formula CH3CH(OH)CH2CH2OH.
With two alcohol functional groups, the molecule is classified as a diol.
The compound is a colorless, bittersweet, water-soluble liquid.
It is one of four common structural isomers of butanediol.
Production and uses of Butane-1,3-diol
Hydrogenation of 3-hydroxybutanal gives 1,3-butanediol:
CH3CH(OH)CH2CHO + H2 → CH3CH(OH)CH2CH2OH
Dehydration of 1,3-butanediol gives 1,3-butadiene:
CH3CH(OH)CH2CH2OH → CH2=CH-CH=CH2 + 2 H2O
Occurrence of Butane-1,3-diol
In biology, Butane-1,3-diol is used as a hypoglycaemic agent.
Butane-1,3-diol can be converted into β-hydroxybutyrate and serve as a substrate for brain metabolism.
Butane-1,3-diol has been detected, but not quantified, in several different foods, such as green bell peppers, orange bell peppers, pepper (c. annuum), red bell peppers, and yellow bell peppers.
Butane-1,3-diol , also referred to as 1,3-Butylene glycol, maintains FDA GRAS status as a flavor molecule.
Butane-1,3-diol is a butanediol compound having two hydroxy groups in the 1- and 3-positions.
Butane-1,3-diol is a butanediol and a glycol.
Use and Manufacturing of Butane-1,3-diol
Sources/Uses
Used as an intermediate in the manufacture of polyester plasticizers; as a humectant for cellophane and tobacco; in polyurethanes and special polyester resins; in surface active agents; as a coupling agent; as a solvent; as a food additive and flavoring; in the cosmetics and pharmaceutical industries as a glycerin substitute; for deicing of aircraft;
For 1,3-butanediol (USEPA/OPP Pesticide Code: 042205) there are 0 labels match. /SRP: Not registered for current use in the U.S., but approved pesticide uses may change periodically and so federal, state and local authorities must be consulted for currently approved uses./
Industry Uses of Butane-1,3-diol
-Intermediates
-Solvents (which become part of product formulation or mixture)
Consumer Uses of Butane-1,3-diol
-Personal care products
Household Products of Butane-1,3-diol
Household & Commercial/Institutional Products
Information on 158 consumer products that contain Butylene glycol in the following categories is provided:
-Auto Products
-Inside the Home
-Personal Care
General Manufacturing Information
Industry Processing Sectors
-All other basic organic chemical manufacturing
-All other chemical product and preparation manufacturing
-Plastic material and resin manufacturing
Butane-1,3-diol , also known as b-butylene glycol or BD, belongs to the class of organic compounds known as secondary alcohols.
Secondary alcohols are compounds containing a secondary alcohol functional group, with the general structure HOC(R)(R') (R,R'=alkyl, aryl).
Butane-1,3-diol is a bitter and odorless tasting compound.
Butane-1,3-diol has been detected, but not quantified, in several different foods, such as green bell peppers, orange bell peppers, pepper (c. annuum), red bell peppers, and yellow bell peppers.
This could make Butane-1,3-diol a potential biomarker for the consumption of these foods.
A butanediol compound having two hydroxy groups in the 1- and 3-positions.
Colorless, slightly bitter sweet viscous liquid.
Melting Point -50 °c.
Boiling point 207.5 °c.
The relative density was 1. 0043.
Viscosity (25 °c) 103. 9MPA.
Surface tension (25 °c) 37.8mN/m.
Soluble in water, acetone, methyl-ethyl (methyl) ketone, ethanol, dibutyl phthalate, castor oil, almost insoluble in aliphatic hydrocarbons, benzene, toluene, carbon tetrachloride, ethanol Amine, mineral oil, linseed oil.
Heat can dissolve nylon, also can partially dissolve shellac and rosin.
Due to the high boiling point, atmospheric pressure distillation is susceptible to air oxidation, it is desirable to distillation under reduced pressure.
Strong hygroscopicity.
Butane-1,3-diol benefits
Butane-1,3-diol has some health benefits if you have dry skin on your face or frequent breakouts.
But it won’t work the same way for every person.
Generally, most people who have dry skin can use products with Butane-1,3-diol to reduce their symptoms.
Butane-1,3-diol is considered to be largely safe for use as a topical skin care ingredient.
While it’s a type of alcohol, it doesn’t typically irritate or dry out skin.
Butane-1,3-diol is an organic alcohol derived from petroleum and is water-soluble.
For cosmetic purposes, Butane-1,3-diol comes in a liquid form and is found in countless skincare products such as cleansers, moisturizers, and masks, as well as makeup and haircare products.
Butane-1,3-diol has many different roles in skincare formulations (it's a humectant, solvent, and emollient) and is used as an alternative to the more commonly known controversial ingredient propylene glycol.
Butane-1,3-diol is an organic alcohol used as a solvent and conditioning agent in cosmetics industry.
Butane-1,3-diol is a water soluble, colorless liquid.
Butane-1,3-diol is mainly used in leave-on and rinse-off formulations.
Butane-1,3-diol is classified as :
-Humectant
-Masking
-Skin conditioning
-Solvent
-Viscosity controlling
Butane-1,3-diol is included in formulas for these types of products because it adds moisture and conditions hair and skin.
Butane-1,3-diol also works as a solvent, meaning it keeps other ingredients, dyes, and pigments from clumping up inside of a solution.
Like all glycols, Butane-1,3-diol is a type of alcohol.
Butane-1,3-diol’s often made from distilled corn.
There are some health concerns that surround the use of Butane-1,3-diol.
Some experts warn against its use, and cite it on lists of ingredients to avoid when choosing self-care products.
The risk in using Butane-1,3-diol is still somewhat unclear.
More research is needed to understand how it can affect your body in the long term.
Butane-1,3-diol, sometimes referred to as “butanediol,” is an organic alcohol that is prevalent in skincare products.
Because Butane-1,3-diol possesses a high number of hydroxyl groups in its chemical structure, it works well in skincare formulations as both a slip agent and a humectant.
A slip agent is a viscosity-decreasing component that thins creams and gels so that they become easier to spread onto the skin surface.
Humectants can help to boost the skin’s ability to retain moisture from the air.
With these properties combined, Butane-1,3-diol is an ideal skincare ingredient for stabilizing and improving the spreadability of lotions and creams, while providing a silky smooth,
moisturizing texture.
FIRST AID MEASURES of Butane-1,3-diol
General Advice
If medical attention is required, show this safety data sheet to the doctor.
If Inhaled
If inhaled, move person to fresh air.
If not breathing, give artificial respiration and consult a physician.
In Case of Skin Contact
Wash affected area with soap and water.
Consult a physician if any exposure symptoms are observed.
In Case of Eye Contact
Immediately rinse eyes with plenty of water for at least 15 minutes.
Consult a physician.
If Swallowed
Never give anything by mouth to an unconscious person.
Rinse mouth with water.
Do NOT induce vomiting unless advised to do so by a physician or Poison Control Center.
Seek medical attention.
Substance identity
EC / List no.: 203-529-7
CAS no.: 107-88-0
Mol. formula: C4H10O2
Hazard classification & labelling of Butane-1,3-diol
According to the notifications provided by companies to ECHA in REACH registrations no hazards have been classified.
About Butane-1,3-diol
Butane-1,3-diol is registered under the REACH Regulation and is manufactured in and / or imported to the European Economic Area, at ≥ 1 000 to < 10 000 tonnes per annum.
Butane-1,3-diol is used by consumers, in articles, by professional workers (widespread uses), in formulation or re-packing, at industrial sites and in manufacturing.
Consumer Uses of Butane-1,3-diol
Butane-1,3-diol is used in the following products: cosmetics and personal care products, perfumes and fragrances, washing & cleaning products and pharmaceuticals.
Other release to the environment of Butane-1,3-diol is likely to occur from: indoor use (e.g. machine wash liquids/detergents, automotive care products, paints and coating or adhesives, fragrances and air fresheners) and outdoor use as processing aid.
Article service life of Butane-1,3-diol
Other release to the environment of Butane-1,3-diol is likely to occur from: indoor use in long-life materials with low release rate (e.g. flooring, furniture, toys, construction materials, curtains, foot-wear, leather products, paper and cardboard products, electronic equipment).
Butane-1,3-diol can be found in products with material based on: paper (e.g. tissues, feminine hygiene products, nappies, books, magazines, wallpaper).
Widespread uses by professional workers of Butane-1,3-diol
Butane-1,3-diol is used in the following products: cosmetics and personal care products, laboratory chemicals, metal surface treatment products, adhesives and sealants, fillers, putties, plasters, modelling clay, non-metal-surface treatment products and lubricants and greases. This substance is used in the following areas: health services, scientific research and development and formulation of mixtures and/or re-packaging.
Release to the environment of Butane-1,3-diol can occur from industrial use: formulation of mixtures.
Other release to the environment of Butane-1,3-diol is likely to occur from: indoor use (e.g. machine wash liquids/detergents, automotive care products, paints and coating or adhesives, fragrances and air fresheners) and outdoor use as processing aid.
Formulation or re-packing of Butane-1,3-diol
Butane-1,3-diol is used in the following products: cosmetics and personal care products, pharmaceuticals, textile treatment products and dyes, washing & cleaning products, metal surface treatment products, adhesives and sealants, fillers, putties, plasters, modelling clay and non-metal-surface treatment products.
Release to the environment of Butane-1,3-diol can occur from industrial use: formulation of mixtures and formulation in materials.
Uses at industrial sites of Butane-1,3-diol
Butane-1,3-diol is used in the following products: polymers, pharmaceuticals, laboratory chemicals, non-metal-surface treatment products and paper chemicals and dyes.
Butane-1,3-diol has an industrial use resulting in manufacture of another substance (use of intermediates).
Butane-1,3-diol is used in the following areas: health services and scientific research and development.
Butane-1,3-diol is used for the manufacture of: plastic products, chemicals, pulp, paper and paper products and machinery and vehicles.
Release to the environment of Butane-1,3-diol can occur from industrial use: as an intermediate step in further manufacturing of another substance (use of intermediates), for thermoplastic manufacture, as processing aid, in the production of articles and in processing aids at industrial sites.
Manufacture of Butane-1,3-diol
Release to the environment of Butane-1,3-diol can occur from industrial use: manufacturing of the substance.
Synonyms:
1,3-BUTANEDIOL
Butane-1,3-diol
107-88-0
1,3-Butylene glycol
1,3-Dihydroxybutane
Methyltrimethylene glycol
beta-Butylene glycol
1,3 Butylene glycol
1,3-Butandiol
1-Methyl-1,3-propanediol
(RS)-1,3-Butandiol
(+/-)-1,3-Butanediol
1,3-Butylenglykol
1,3-Butanodiol
.beta.-Butylene glycol
BD
NSC 402145
BUTANEDIOL,1,3-
NSC-402145
1,3-Butanediol, homopolymer
CHEBI:52683
NSC6966
DSSTox_CID_6773
DSSTox_RID_78210
DSSTox_GSID_26773
Caswell No. 128GG
Butane-1,3-diol (Butylene Glycol)
1,3-Butandiol [German]
1,3-butane diol
55251-78-0
CAS-107-88-0
1,3-Butylenglykol [German]
HSDB 153
r-(-)-1,3-butanediol
1,3-Butanediol, (R)-
1,3-Butanediol, (S)-
S-(+)-1,3-Butanediol
EINECS 203-529-7
BRN 1731276
Aliphatic diol
AI3-11077
b-Butylene glycol
1.3-butanediol
1,3 -butanediol
MFCD00004554
DL-1,3-butanediol
Butylene glycol (NF)
(S)-(+)-butanediol
racemic 1,3-butanediol
BUTANEDIOL,3-
1,3-butanediol, DL-
(RS)-1,3-Butanediol
( inverted exclamation markA)-1,3-Butanediol
EC 203-529-7
(+/-) 1,3 butandiol
(+/-)-1,3-butandiol
0-01-00-00477 (Beilstein Handbook Reference)
(.+/-.)-1,3-Butanediol
CHEMBL3186475
DTXSID8026773
WLN: QY1 & 2Q
1,3-Butanediol, (.+/-.)-
NSC-6966
Tox21_202408
Tox21_300085
BBL037424
Butylene Glycol (Butane-1,3-diol)
HY-77490A
NSC402145
STL483070
AKOS000119043
DB14110
MCULE-1694239851
SB44648
SB44659
NCGC00247900-01
NCGC00247900-02
NCGC00253944-01
NCGC00259957-01
SY049450
DB-000434
DB-011642
(+/-)-1,3-Butanediol, analytical standard
B0679
B3770
CS-0115644
FT-0605126
FT-0605294
FT-0606593
(+/-)-1,3-Butanediol, anhydrous, >=99%
1,3-Butanediol 100 microg/mL in Acetonitrile
C20335
D10695
Q161496
(+/-)-1,3-Butanediol, ReagentPlus(R), 99.5%
J-002028
(+/-)-1,3-Butanediol, ReagentPlus(R), >=99.0%
(+/-)-1,3-Butanediol, SAJ first grade, >=98.0%
(+/-)-1,3-Butanediol, Vetec(TM) reagent grade, 98%
F8880-3340
Butane-1,3-diol, United States Pharmacopeia (USP) Reference Standard
(-)-1,3-Butanediol
(3R)-1,3-Butandiol [German] [ACD/IUPAC Name]
(3R)-1,3-Butanediol [ACD/IUPAC Name]
(3R)-1,3-Butanediol [French] [ACD/IUPAC Name]
(3R)-Butane-1,3-diol
(R)-(-)-1,3-Butanediol
(R)-Butane-1,3-diol
1,3-Butanediol, (3R)- [ACD/Index Name]
1,3-Butanediol, (R)-
228-532-0 [EINECS]
6290-03-5 [RN]
MFCD00064277 [MDL number]
"(R)-BUTANE-1,3-DIOL"|"(3R)-BUTANE-1,3-DIOL"
(3R)-(-)-1,3-Dihydroxybutane
(3R)-(-)-Butane-1,3-diol
(3R)-(-)-Butane-1,3-diol|(3R)-(-)-1,3-Dihydroxybutane
(3S)-Butane-1,3-diol
(R)-(−)-1,3-Butanediol
(R)-(-)-1,3-Butanediol (en)
(R)-(-)-1,3-Butanediol|(R)-(-)-1,3-Butylene glycol
(R)-(-)-1,3-Butylene glycol
(R)-(-)-1,3-ButyleneGlycol
(R)-(-)-butane-1,3-diol
(R)-1,3-Butanediol
(S)-()-1,3-Butanediol
[6290-03-5] [RN]
1,3-Butanediol [ACD/Index Name] [ACD/IUPAC Name]
107-88-0 [RN]
203-529-7 [EINECS]
25265-75-2 [RN]
3-Indolemethanol
BU2
BU4
Butane-1,3-diol
BUTANEDIOL (MIXED ISOMERS)
Butylene glycol
L-Butane-1,3-diol
OR-3422
PUPZLCDOIYMWBV-SCSAIBSYSA-N
R-(-)-1,3-Butanediol
R-butane-1,3-diol
UNII-3XUS85K0RA
(RS)-1,3-Butandiol
1,3-Butandiol
1,3-Butanediol
1,3-butanediol
1,3-Butylene glycol
1,3-Butylenglykol
1,3-Dihydroxybutane
1-Methyl-1,3-propanediol
beta-Butylene glycol
Butane-1,3-diol
Butane-1,3-diol
butane-1,3-diol
Butylene glycol
Methyltrimethylene glycol
1,3-Butanediol
(+/-)-Butane-1,3-diol
C&L Inventory
(3R)-butane-1,3-diol; (3S)-butane-1,3-diol
1,3-BUTANEDIOL
1,3-Butanediol
1,3-BUTYLENE GLYCOL
1,3-Butylene glycol
1,3-Butylene Glycol
1,3-Butylene glycol
Butan-1,3-diol
Butane-1,2 diol
Butane-1,3-diol
butane-1,3-diol
Butane-1,3-diol
Butane-1,3-diol (1,3-BUTANEDIOL (8CI9CI))
Butylene glycol
1,3-Butanediol (8CI, 9CI)
1,3-Butylene Glycol
1,3-Butylene glycol
1,3-Dihydroxybutane
1-Methyl-1,3-propanediol
3-Hydroxy-1-butanol
BUTANE-1,3-DIOL
Butylene glycol
HAISUGARCANE BG
HAISUGARCANE BG-R
Methyltrimethylene glycol
NaturoBG
β-Butylene glycol
107-88-0
18826-95-4
18826-95-4
817176-75-3
817176-75-3
