BUTANE-1,4-DIOL

Butane-1,4-diol is an organic compound, with the formula HOCH2CH2CH2CH2OH. 
Butane-1,4-diol is a colorless viscous liquid. 
Butane-1,4-diol is one of four stable isomers of butanediol.

CAS NUMBER: 110-63-4

EC NUMBER: 203-786-5

MOLECULAR FORMULA: HO(CH2)4OH

MOLECULAR WEIGHT: 90.12

IUPAC NAME: butane-1,4-diol

Butane-1,4-diol, not to be confused with 1,3 butanediol, is a primary alcohol
Butane-1,4-diol is used to produce polybutyleneterephthalate

Butane-1,4-diol is used as a thermoplastic polyester
Butane-1,4-diol is used in making tetrahydrofuran, butyrolactones,and polymeric plasticizers.

Synthesis of Butane-1,4-diol: 
In industrial chemical synthesis, acetylene reacts with two equivalents of formaldehyde to form butyne-1,4-diol. 
Hydrogenation of Butane-1,4-diol gives butane-1,4-diol. 
Butane-1,4-diol is also made on an industrial scale from maleic anhydride in the Davy process, which is first converted to the methyl maleate ester, then hydrogenated. 
Other routes are from butadiene, allyl acetate and succinic acid.

Industrial Uses: 
Butane-1,4-diol is used industrially as a solvent and in the manufacture of some types of plastics, elastic fibers and polyurethanes. 
In organic chemistry, Butane-1,4-diol is used for the synthesis of γ-butyrolactone.
In the presence of phosphoric acid and high temperature, it dehydrates to the important solvent tetrahydrofuran.
At about 200 °C in the presence of soluble ruthenium catalysts, the diol undergoes dehydrogenation to form butyrolactone.
Butane-1,4-diol is used to synthesize 1,4-Butanediol diglycidyl ether which is then used as a reactive diluent for epoxy resins.

Butane-1,4-diol appears as odorless colorless liquid or solid (depending upon temperature)
Butane-1,4-diol is a butanediol that is butane in which one hydrogen of each of the methyl groups is substituted by a hydroxy group. 

Butane-1,4-diol is colourless and water-miscible
Butane-1,4-diol is a viscous liquid at room temperature (m.p. 16℃)

Butane-1,4-diol's boiling point is 230℃
Butane-1,4-diol is mainly used for the production of other organic chemicals, particularly the solvent oxolane (also known as tetrahydrofuran or THF). 

Butane-1,4-diol has a role as a neurotoxin, a protic solvent and a prodrug. 
Butane-1,4-diol is a butanediol and a glycol.

Butane-1,4-diol is a butanediol that is butane in which one hydrogen of each of the methyl groups is substituted by a hydroxy group. 
Butane-1,4-diol is a colourless and water-miscible

Butane-1,4-diol is viscous liquid at room temperature
Butane-1,4-diol's melting point is 16°C

Butane-1,4-diol has a high boiling point (230°C)
Butane-1,4-diol is mainly used for the production of other organic chemicals, particularly the solvent oxolane

Butane-1,4-diol is a colorless, viscous liquid derived from butane by placement of alcohol groups at each end of its molecular chain
Butane-1,4-diol is one of four stable isomers of butanediol.

The hydroxyl function of each end group of the Butanediol: 
Butane-1,4-diol reacts with different mono- and bifunctional reagents

Butane-1,4-diol (BDO) is a high-quality intermediate. 
Butane-1,4-diol and its derivatives are widely used for producing plastics, solvents, electronic chemicals and elastic fibers. 

Additionally Butane-1,4-diol is also a building block for the synthesis of polyesterpolyols and polyetherpolyols. 
Butane-1,4-diol is a solvent with good antimicrobial action. 

Butane-1,4-diol enhances the preservative activity of parabens. 
Butane-1,4-diol also serves as a humectant and viscosity controller, and to mask odor.

USES:
Butane-1,4-diol and its derivatives is used in a broad spectrum of applications in the chemical industry; amongst others in the manufacturing of technical plastics, polyurethanes, solvents, electronic chemicals and elastic fibres.
Butane-1,4-diol is used in the synthesis of epothilones, a new class of cancer drugs. 

Butane-1,4-diol also used in the stereoselective synthesis of (-)-Brevisamide.
Butane-1,4-diol's largest use is within tetrahydrofuran (THF) production, used to make polytetramethylene ether glycol, which goes mainly into spandex fibers, urethane elastomers, and copolyester ethers.

Butane-1,4-diol is commonly used as a solvent in the chemical industry to manufacture gamma-butyrolactone and elastic fibers like spandex.
Butane-1,4-diol is used as a cross-linking agent for thermoplastic urethanes, polyester plasticizers, paints and coatings.

Butane-1,4-diol undergoes dehydration in the presence of phosphoric acid yielded teterahydrofuran, which is an important solvent used for various applications.
Butane-1,4-diol acts an intermediate and is used to manufacture polytetramethylene ether glycol (PTMEG), polybutylene terephthalate (PBT) and polyurethane (PU).

Butane-1,4-diol finds application as an industrial cleaner and a glue remover.
Butane-1,4-diol is also used as a plasticiser (e.g. in polyesters and cellulosics)

Butane-1,4-diol is used as a carrier solvent in printing ink
Butane-1,4-diol can be used as a cleaning agent

Butane-1,4-diol also used as an adhesive (in leather, plastics, polyester laminates and polyurethane footwear)
Butane-1,4-diol is used in agricultural and veterinary chemicals and in coatings (in paints, varnishes and films).

PHYSICAL PROPERTIES: 

-Molecular Weight: 90.12    

-XLogP3: -0.8        

-Exact Mass: 90.068079557    

-Monoisotopic Mass: 90.068079557    

-Topological Polar Surface Area: 40.5 Ų

-Physical Description: odorless colorless liquid

-Color: Colorless

-Form: oily liquid

-Odor: Almost odorless

-Boiling Point: 235 °C

-Melting Point: 20.1 °C

-Flash Point: 121 °C

-Solubility: Soluble in water

-Density: 1.0171 g/cu cm

-Vapor Density: 3.1

-Vapor Pressure: 0.01 mmHg

-Autoignition Temperature: 350 °C

-Viscosity: 84.9 mPa.s

-Surface Tension: 44.6 mN/m

-Refractive Index: 1.4460

Butane-1,4-diol is used industrially as a solvent and in the manufacture of some types of plastics, elastic fibers and polyurethanes. 
In organic chemistry, Butane-1,4-diol is used for the synthesis of γ-butyrolactone (GBL).

Butane-1,4-diol is a colorless viscous liquid. 
Butane-1,4-diol is one of four stable isomers of butanediol. 
Butane-1,4-diol is used industrially as a solvent

CHEMICAL PROPERTIES: 

-Hydrogen Bond Donor Count: 2    

-Hydrogen Bond Acceptor Count: 2    

-Rotatable Bond Count: 3

-Heavy Atom Count: 6    

-Formal Charge: 0    

-Complexity: 17.5    

-Isotope Atom Count: 0    

-Defined Atom Stereocenter Count: 0    

-Undefined Atom Stereocenter Count: 0    

-Defined Bond Stereocenter Count: 0    

-Undefined Bond Stereocenter Count: 0    

-Covalently-Bonded Unit Count: 1    

-Compound Is Canonicalized: Yes

-Chemical Classes: Other Classes -> Alcohols and Polyols, Other

Butane-1,4-diol is used to produce polybutyleneterephthalate
Butane-1,4-diol is used as a thermoplastic polyester

Butane-1,4-diol is used in making tetrahydrofuran, butyrolactones,and polymeric plasticizers.
Butane-1,4-diol is used to synthesize 1,4-Butanediol diglycidyl ether which is then used as a reactive diluent for epoxy resins.

Butane-1,4-diol appears as colorless liquid
Butane-1,4-diol is water-miscible

Butane-1,4-diol is a viscous liquid
Butane-1,4-diol is mainly used for the production of other organic chemicals

Butane-1,4-diol has a role as a protic solvent
Butane-1,4-diol is a glycol.

Butane-1,4-diol is a colourless liquid
Butane-1,4-diol is viscous liquid at room temperature

Butane-1,4-diol is derived from butane
Butane-1,4-diol is one of four stable isomers of butanediol.

Butane-1,4-diol is used in the synthesis of epothilones, a new class of cancer drugs. 
Butane-1,4-diol also used in the stereoselective synthesis of (-)-Brevisamide.

Butane-1,4-diol is used to manufacture polytetramethylene ether glycol
Butane-1,4-diol finds application as a glue remover

Butane-1,4-diol is also used as a plasticiser
Butane-1,4-diol can be used as a cleaning agent
Butane-1,4-diol also used as an adhesive 

SYNONYMS: 

1,4-BUTANEDIOL
Butane-1,4-diol
110-63-4
1,4-Butylene glycol
Tetramethylene glycol
1,4-Dihydroxybutane
1,4-Tetramethylene glycol
Tetramethylene 1,4-diol
Sucol B
1,4-BD
EINECS 203-786-5
4-hydroxybutanol
1,4butanediol
1.4-butanediol
Dabco BDO
1,4-butandiol
1,4-butane diol
1,4-butane-diol
butane 1,4-diol
butane diol-1,4
butane-1-4-diol
1,4- butandiol
Butan-1.4-diol
1.4 - butanediol
1,4 butylene glycol
1,4-Butanediol, 99%
EC 203-786-5
4-01-00-02515
1,4-BUTANEDIOL
1,4-BUTANEDIOL
1,4-BUTANEDIOL
1,4-Butanediol
1,4-BD
1,4-BUTANEDIOL
1,4-butylene glycol
1,4-dihydroxybutane
1,4-tetramethylene glycol
HO(CH2)4OH    
HOCH2CH2CH2CH2OH    
tetramethylene 1,4-diol    
tetramethylene glycol
BDO
Butylene glycol
Butanediol
BUTANE-1,4-DIOL
TETRAMETHYLENE GLYCOL
1,4-Butandiol
1,4-BD
sucolb
Diol 14B
4-Butanediol
1,4-butylene glycol
110-63-4 
200-659-6
203-786-5 
7XOO2LE6G3
butane-1,4-diol
MFCD00002968 
POLYURETHANE
"BUTANE-1,4-DIOL"
(3S)-Butane-1,3-diol
(S)-()-1,3-Butanediol
1,4 butylene glycol
1,4-butane diol
1,4-butanediol (bdo)
1,4-Butanediol;BDO
1,4-Butanediol-2,2,3,3-d4
1,4-Butanediol-d10
1,4-Butanediol-d8
1,4-Butanediolmissing
1,4-Dihydroxybutane
1,4-Tetramethylene glycol