Butylated Hydroxytoluene (BHT) is used as an antioxidant or stabilizer.
Butylated Hydroxytoluene (BHT) plays an important role in maintaining quality and performance of raw materials and products by preventing their deterioration due to the reaction with oxygen in the air (oxidation).
Butylated Hydroxytoluene (BHT) is used in a wide range of fields, including resins, rubber, textile processing, packaging materials, food additives, cosmetics, detergents, and pharmaceuticals.
CAS Number: 128-37-0
EC Number: 204-881-4
MDL number: MFCD00011644
Molecular Formula: C15H24O / [(CH3)3C]2C6H2(CH3)OH
Molecular Weight: 220.35 g/mol
SYNONYMS:
2,6-Bis(1,1-dimethylethyl)-4-methylphenol, 2,6-Di-tert-butyl-p-cresol, BHT, Butylated hydroxytoluene, DBPC, 2,6-Di-tert-butyl-4-methylphenol, Dibutylhydroxytoluene, Antioxidant 264, 2,6-Di-tert-butyl-4-methylphenol, Butylhydroxytoluene, Butylated hydroxytoluene, BHT, 2,6-Di-tert-butyl-4-methylphenol, 2,6-Di-tert-butyl-p-cresol, BHT, Butylated hydroxytoluene, Butylhydroxytoluene, DBPC, 2,6-Di-tert-butyl-4-methylphenol (BHT), E321, Butylhydroxytoluenum, 2,6-Di-tert-butyl-4-methylphenol, 4-methyl-2,6-ditertbutylphenol, Butylhydroxytoluene, 2,6-Di-tert-butyl-p-cresol, 2,6-Di-t-butyl-4-methylphenol, 2,6-bis(1,1-dimethylethyl)-4-methylphenol, butylated hydroxytoluene, 2,6-di-tert-butyl-p-cresol (DBPC), 3,5-di-tert-butyl-4-hydroxytoluene, 1,3-di-tert-butyl-2-hydroxy-5-methyl benzene, di-tert-butyl-methylphenol, 2,6-DITERTIARY-BUTYL-p-CRESOL, 4-METHYL-2,6-DITERTIARY-BUTYL-PHENOL, Phenol, 2,6-bis(1,1-dimethylethyl)-4-methyl-, p-Cresol, 2,6-di-tert-butyl-, Dalpac, Deenax, Di-tert-butyl-p-cresol, Di-tert-butyl-p-methylphenol, Di-tert-butylcresol, Dibunol, Dibutylated hydroxytoluene, Ionol, Nonox TBC, Parabar 441, Stavox, Sumilizer BHT, Sustane BHT, Tenamene 3, Tenox BHT, Topanol, Vanlube PC, Vanlube PCX, Vianol, 2,6-Bis(1,1-dimethylethyl)-4-methylphenol, 2,6-Di-tert-butyl-p-cresol, 2,6-Di-tert-butyl-p-methylphenol, 2,6-Di-tert-butyl-4-methylphenol, 3,5-Di-tert-butyl-4-hydroxytoluene, 4-Hydroxy-3,5-di-tert-butyltoluene, 4-Methyl-2,6-di-tert-butylphenol, 2,6-Di-t-butyl-4-methylphenol, 2,6-Di-tert-butyl-1-hydroxy-4-methyl benzene, 2,6-di-Butyl-para-cresol, 2,6-di-tert-Butyl-methylphenol, o-Di-tert-butyl-p-methylphenol, Butylated hydroxytoluol, DBMP, 1-Hydroxy-4-methyl-2,6-di-tert-butylbenzene, 2,6-Di-terc.butyl-p-kresol, 2,6-Di-tert-butyl-4-cresol, 4-Methyl-2,6-di-terc. butylfenol, 4-Methyl-2,6-tert-butylphenol, Di-tert-Butylparamethylphenol, Di-tert-Butyl-4-methylphenol, 2,6-Di-t-butyl-p-cresol, Phenol, 2,6-di-tert-butyl-4-methyl-, 4-Methyl-2,6-di-t-butyl-phenol, BHT (butylated hydroxytoluene), 2,6-di-ter-butyl-4-methyl-phenol, 2,6-Di-tert-butyl-para-methylphenol, 2,6-di-tert-butyl-p-cresol (BHT), Butylated hydroxyl toluene (BHT), Dibutylhydroxytoluene, Dibutylcresol, 2,6-Bis(tert-butyl)-4-methylphenol, 2,6-Di(tert-butyl)hydroxytoluene, 2,6-di-ter-butul-4-methyl-phenol, 4-Methyl-2,6-di-tert.-butylphenol, Di-ter-butyl p-cresol, butylated OH tolueno, Dibutyl-p-cresol, Ergotamine, dihydro-, monomethanesulfonate (salt), 2,6-Di-tert-butyl-4-methylphenol, 2,6-Di-tert-butyl-p-cresol, 2,6-DI-tert-butyl-4-methylphenol, 3,5-Di-tert-butyl-4-hydroxytoluene, 2,6 ditertiary-butyl-4-methyl phenol, DBPC, BHT, E321, AO-29, Avox BHT, Antioxidant 264, Additin RC 7110, Dibutylated hydroxytoluene, 4-Methyl-2,6-di-tert-butyl phenol, 3,5-(Dimethylethyl)-4-hydroxytoluene, E321: Food additive code, Butylhydroxytoluene, BHT, 2,6-Di-t-butyl-4-methylphenol, 128-37-0, Antioxidant, Lonol (Antioxidant), Dibutylated Hydroxytoluene, 2,6-Di-tert-butyl-4-methylphenol, BHT, 2,6-Di-tert-butyl-4-methylphenol, Dibutylhydroxytoluene, Butylhydroxytoluene, Phenol, 2,6-bis(1,1-dimethylethyl)-4-methyl-, 2,6-di-t-butyl-p-cresol, Di-tert-butyl-p-cresol, 3,5-Di-tert-butyl-4-hydroxytoluene, 4-hydroxy-3,5-di-tert-butyltoluene, Ionol, Topanol O, Antioxidant DBPC, Sustane BHT, DBMP, BUKS, 2,6-Di-tert-butyl-4-methylphenol, 2,6-Di-tert-butyl-p-cresol, BHT, Butylated hydroxytoluene, Butylhydroxytoluene, DBPC, Phenol, 2,6-bis(1,1-dimethylethyl)-4-methyl-, p-Cresol, 2,6-di-tert-butyl-, Advastab 401, Antioxidant DBPC, Antioxidant KB, Antioxidant 29, Antioxidant 30, Antioxidant 4K, AO 29, AO 4K, Butylhydroxytoluene, BHT, BUKS, Catalin Antioxydant 1, Catalin CAO-3, Chemanox 11, CAO 1, CAO 3, Dalpac, Deenax, Di-tert-butyl-p-cresol, Di-tert-butyl-p-methylphenol, Di-tert-butylcresol, Dibunol, Dibutylated hydroxytoluene, DBPC, Impruvol, Ionol, Ionol (Antioxidant), Ionol CP, Ionol 1, Ionole, Nonox TBC, P 21, Parabar 441, Stavox, Sumilizer BHT, Sustane BHT, Tenamene 3, Tenox BHT, Topanol, Topanol O, Topanol OC, Vanlube PC, Vanlube PCX, Vianol, 2,6-Bis(1,1-dimethylethyl)-4-methylphenol, 2,6-Di-tert-butyl-p-cresol, 2,6-Di-tert-butyl-p-methylphenol, 2,6-Di-tert-butyl-4-methylphenol, 3,5-Di-tert-butyl-4-hydroxytoluene, 4-Hydroxy-3,5-di-tert-butyltoluene, 4-Methyl-2,6-di-tert-butylphenol, 2,6-Di-t-butyl-4-methylphenol, 2,6-Di-tert-butyl-1-hydroxy-4-methyl benzene, 2,6-di-Butyl-para-cresol, 2,6-di-tert-Butyl-methylphenol, o-Di-tert-butyl-p-methylphenol, Bht(food grade), Butylated hydroxytoluol, Dbpc(technical grade), DBMP, NCI-C03598, Paranox 441, 1-Hydroxy-4-methyl-2,6-di-tert-butylbenzene, 2,6-Di-terc.butyl-p-kresol, 2,6-Di-tert-butyl-4-cresol, 4-Methyl-2,6-di-terc. butylfenol, 4-Methyl-2,6-tert-butylphenol, Di-tert-Butylparamethylphenol, Di-tert-Butyl-4-methylphenol, 2,6-Di-t-butyl-p-cresol, Phenol, 2,6-di-tert-butyl-4-methyl-, 4-Methyl-2,6-di-t-butyl-phenol, Annulex BHT, Antrancine 8, Lowinox BHT, Nipanox BHT, Ralox BHT, Sustane, Vulkanox KB, BHT (butylated hydroxytoluene), 2,6-di-ter-butyl-4-methyl-phenol, 2,6-Di-tert-butyl-para-methylphenol, 2,6-di-tert-butyl-p-cresol (BHT), Butylated hydroxyl toluene (BHT), Dibutylhydroxytoluene, Dibutylcresol, 2,6-Bis(tert-butyl)-4-methylphenol, 2,6-Di(tert-butyl)hydroxytoluene, Ionol BHT, BHT Swanox, Agidol, 2,6-di-ter-butul-4-methyl-phenol, 4-Methyl-2,6-di-tert.-butylphenol, Di-ter-butyl p-cresol, butylated OH tolueno, Dibutyl-p-cresol, Ergotamine, dihydro-, monomethanesulfonate (salt), Hydagen DEO (Salt/Mix), advastab 401, agidol, alkofen BP, annulex BHT, antioxidant 264, antioxidant 29, antioxidant 30, antioxidant 4, antioxidant DBPC, antioxidant KB, antioxidant MPJ, antioxidant T 501, antox QT, antracine 8, antrancine 8, B.H.T., BHT, BHT (butylated hydroxy toluene) tech grade, BHT FCC/NF, 2,6-bis(tert- butyl)-4-methylphenol, catalin antioxydant 1, catalin CAO-3, chemanox 11, (2,5- cyclohexadiene-1,4-diylidene)-dimalononitrile, dalpac, deenax, 2,6- di-(tert-butyl)-4-methylphenol, 2,6- di-t-butyl-4-methylphenol, 2,6- di-t-butyl-p-cresol, 2,6- di-tert-butyl-1-hydroxy-4-methylbenzene, 2,6- di-tert-butyl-4-cresol, 2,6- di-tert-butyl-4-hydroxytoluene, 2,6- di-tert-butyl-4-methyl phenol, 2,6- di-tert-butyl-4-methylhydroxybenzene, 2,6- di-tert-butyl-4-methylphenol, 2,6- di-tert-butyl-p-cresol, 2,6- di-tert-butyl-p-methylphenol, 2,6- di-tert-butyl-para-cresol, 2,6- di-tert-butylcresol, 2,6-bis(1,1- dimethylethyl)-4-methylphenol, embanox BHT, hydagen DEO, butylated hydroxy toluene, butylated hydroxy toluene (BHT) N.F. grade powder (40 mesh), 4- hydroxy-3,5-di-tert-butyltoluene, 1- hydroxy-4-methyl-2,6-di-tert-butylbenzene, butylated hydroxytoluene (BHT) N.F. grade powder (60 mesh), butylated hydroxytoluene (BHT) FCC grade, butylated hydroxytoluene (BHT) N.F. grade, butylated hydroxytoluene (BHT) NF & EP grade, butylated hydroxytoluene NF & EP grade powder (325 mesh), butylated hydroxytoluene NF & EP grade powder (60 mesh), butylated hydroxytoluene NF & EP grade powder (80 mesh), impruvol, ional, kerabit, 4- methyl-2,6-di-t-butyl-phenol, 4- methyl-2,6-ditertbutylphenol, 4- methyl-2,6-tert-butylphenol, nocrac 200, nonox TBC, parabar, paranox 441, tenox BHT food-grade antioxidant, vianol,
Butylated Hydroxytoluene (BHT) is a synthetic, fat-soluble phenolic antioxidant widely used in food, cosmetics, pharmaceuticals, and industrial materials.
Butylated Hydroxytoluene (BHT)'s primary function is to prevent oxidative degradation of lipids and fats, thereby extending shelf life and maintaining product quality.
Butylated Hydroxytoluene (BHT) is chemically stable, effective at low concentrations, and works by interrupting free radical chain reactions responsible for oxidation.
Butylated Hydroxytoluene (BHT) is structurally derived from phenol with tert-butyl groups that enhance its antioxidant activity and lipophilicity, making it especially effective in fat-containing systems.
Butylated Hydroxytoluene (BHT) has been evaluated for safety by regulatory authorities and independent organizations in various countries and regions for its use in pharmaceuticals, foods, and cosmetics, and its safe levels of concentration have been specified.
Butylated Hydroxytoluene (BHT), also known as 2,6-Di-tert-butyl-4-methylphenol, Butylhydroxytoluene, and 2,6-Di-tert-butyl-p-cresol, has the chemical formula C15H24O or C6H2(OH)(CH3)(C(CH3)3)2.
Butylated Hydroxytoluene (BHT) appears as white to pale-yellow, crystalline, or flaked solid with no odor or a characteristic faint aromatic odor.
Butylated Hydroxytoluene (BHT) is insoluble in Water but soluble in Methanol, Toluene, and Ether at ambient conditions.
A derivate of phenol, this white crystalline powder, Butylated Hydroxytoluene (BHT), is a potent antioxidant that has marked its presence as an additive not only in food products but also in cosmeceuticals.
Butylated hydroxytoluene (BHT) is a phenol-derivative with antioxidant properties.
Butylated Hydroxytoluene (BHT) is a common synthetic compound that is used as a preservative in cosmetic formulations to stabilize the formulation and prevent its oxidation.
Butylated Hydroxytoluene (BHT) maintains the properties of a formulation like color, odor, and texture, which may change upon exposure to air.
Butylated hydroxytoluene (BHT) is a man-made chemical commonly used as a preservative in processed foods.
Similar to the synthetic preservative butylated hydroxyanisole (BHA) with which it is often used, Butylated Hydroxytoluene (BHT) is an antioxidant that is soluble in oils and animal fats (it actually has greater solubility than does BHA).
Both BHA and Butylated Hydroxytoluene (BHT) are used to extend shelf life of processed foods by reducing the occurrence of oxidation and rancidity.
Instead of being added directly to the food itself, Butylated Hydroxytoluene (BHT) is usually added to the packaging material from where it vaporizes into the food during storage.
Since Butylated Hydroxytoluene (BHT) may be classified as an incidental food additive when used in this manner, it does not legally need to be listed with other ingredients on the food label.
Processed foods most likely to contain Butylated Hydroxytoluene (BHT) include chewing gum, active dry yeast, frozen convenience foods, prepared cereal products, prepared snacks, dried and processed meat, potato flakes, enriched rice products and shortening.
Butylated Hydroxytoluene (BHT) is also a chemical preservative used in animal feeds and drugs; therefore eatomg non-organic meats and dairy products may be another way in which exposure occurs.
In addition to Butylated Hydroxytoluene (BHT)'s use in food preservation, BHA is also used in the manufacture of rubber, tires and petroleum and is an ingredient in some cosmetics.
Butylated Hydroxytoluene (BHT) is listed by the NIH Hazardous Substances Data Bank under several categories in catalogues and databases, such as food additive, household product ingredient, industrial additive, personal care product/cosmetic ingredient, pesticide ingredient, plastic/rubber ingredient and medical/veterinary/research.
Butylated hydroxytoluene (BHT) is a toluene-based ingredient used as a preservative in food and personal care products.
Butylated Hydroxytoluene (BHT) or Butylhydroxytoluene is a phenol which is in the form of yellowish-white crystals.
USES and APPLICATIONS of BUTYLATED HYDROXYTOLUENE (BHT):
Butylated Hydroxytoluene (BHT) is widely used across multiple industries due to its ability to inhibit oxidation.
In the food industry, Butylated Hydroxytoluene (BHT) is used as a preservative in cereals, snack foods, chewing gum, vegetable oils, butter, and fat-containing processed foods.
Butylated Hydroxytoluene (BHT) helps maintain flavor stability and prevents spoilage caused by lipid oxidation.
In the cosmetic industry, Butylated Hydroxytoluene (BHT) is added to creams, lotions, lipsticks, perfumes, and hair care products to prevent the oxidation of oils and fragrances, ensuring product stability and longer shelf life.
In pharmaceuticals, Butylated Hydroxytoluene (BHT) stabilizes active ingredients and excipients that are sensitive to oxidation, especially in soft gel capsules and lipid-based formulations.
In industrial applications, Butylated Hydroxytoluene (BHT) is used in lubricants, rubber, plastics, fuels, and petroleum products to prevent oxidative degradation and improve material durability.
Butylated Hydroxytoluene (BHT) is used as an antioxidant or stabilizer.
Butylated Hydroxytoluene (BHT) plays an important role in maintaining quality and performance of raw materials and products by preventing their deterioration due to the reaction with oxygen in the air (oxidation).
Butylated Hydroxytoluene (BHT) is used in a wide range of fields, including resins, rubber, textile processing, packaging materials, food additives, cosmetics, detergents, and pharmaceuticals.
Since Butylated Hydroxytoluene (BHT) is heat stable, it is useful to prevent oxidation of certain raw materials during manufacturing processes that involve heating.
Butylated Hydroxytoluene (BHT) is also used to protect oils, fats, and active ingredients such as vitamins that are susceptible to oxidation.
We use the minimum amount of Butylated Hydroxytoluene (BHT) in our products to ensure that they can be used safely until their expiration.
Food Preservation: Butylated Hydroxytoluene (BHT) is commonly added to foods, fats, and oils to prevent oxidation and extend their shelf life.
Butylated Hydroxytoluene (BHT) helps maintain the freshness of products by inhibiting the formation of free radicals, which can cause rancidity and spoilage.
Cosmetics and Personal Care Products: Butylated Hydroxytoluene (BHT) is utilized in various cosmetics and personal care products, such as lipsticks, lip balms, moisturizers, and hair care products, to prevent them from becoming rancid and to extend their stability.
Pharmaceuticals: Butylated Hydroxytoluene (BHT) is used in pharmaceuticals to prevent the oxidation of drugs and maintain their potency and stability.
Butylated Hydroxytoluene (BHT) is often added to medications, vitamins, and supplements that contain fats or oils.
Industrial Applications: Butylated Hydroxytoluene (BHT) is employed as an antioxidant in industrial lubricants, greases, and other petroleum-based products to prevent oxidation and degradation, thereby prolonging their useful life.
Polymer Stabilization: Butylated Hydroxytoluene (BHT) is used as an antioxidant in plastics, polymers, and rubber products to prevent degradation caused by exposure to oxygen, heat, and ultraviolet (UV) radiation during processing, storage, and use.
Fuel Additive: In some cases, Butylated Hydroxytoluene (BHT) is added to fuels, such as gasoline and diesel, as an antioxidant to prevent the formation of gum and deposits in fuel systems and engines.
Insecticides and Pesticides: Butylated Hydroxytoluene (BHT) is sometimes incorporated into insecticides and pesticides to enhance their stability and effectiveness by preventing the degradation of active ingredients due to oxidation.
Butylated Hydroxytoluene (BHT) is used as an antioxidant in cosmetic products.
Antioxidants improve the quality and shelf life of products by slowing down their oxidation processes.
When used in cosmetics, Butylated Hydroxytoluene (BHT) helps prevent discoloration, deterioration, and unpleasant odors that may occur when the products come into contact with air, light, and other external factors.
This preserves the stability and effectiveness of cosmetic products, providing users with fresh and effective products for a longer period.
The usage rate of Butylated Hydroxytoluene (BHT) varies between 0.01% and 0.5%, depending on the effect the product will have and its interaction with other substances.
Butylated hydroxytoluene (BHT) is an antioxidant shown to be chemopreventive against a variety of carcinogens.
As an antioxidant, Butylated hydroxytoluene (BHT) acts as a free radical scavenger, binding to and neutralizing these highly reactive molecules in the body.
By doing so, Butylated Hydroxytoluene (BHT) helps protect cells from damage and reduces oxidative stress, which can otherwise lead to cell damage.
Butylated Hydroxytoluene (BHT) can be used as a preservative in foods and food packaging materials.
Butylated Hydroxytoluene (BHT) is a substance used in many industrial, commercial and consumer applications.
Butylated Hydroxytoluene (BHT) is used for its antioxidant properties in cosmetics.
Cosmetics: The European Union restricts the use of Butylated Hydroxytoluene (BHT) in mouthwash to 0.001% concentration, in toothpaste to 0.01% concentration, and to 0.8% in other cosmetics
Butylated Hydroxytoluene (BHT) is a lab-made chemical that is added to foods as a preservative.
People also use Butylated Hydroxytoluene (BHT) as medicine.
Butylated Hydroxytoluene (BHT) is used to treat genital herpes and acquired immunodeficiency syndrome (AIDS).
Some people apply Butylated Hydroxytoluene (BHT) directly to the skin for cold sores.
Butylated Hydroxytoluene (BHT) is an antioxidant.
-Food additive uses of Butylated Hydroxytoluene (BHT):
Butylated Hydroxytoluene (BHT) is primarily used as an antioxidant food additive.
In the United States, Butylated Hydroxytoluene (BHT) is classified as generally recognized as safe (GRAS) based on a National Cancer Institute study from 1979 in rats and mice.
It is approved for use in the U.S. by the Food and Drug Administration: For example, 21 CFR § 137.350(a)(4) allows Butylated Hydroxytoluene (BHT) up to 0.0033% by weight in "enriched rice", while 9 CFR § 381.147(f)(1) allows up to 0.01% in poultry "by fat content".
It is permitted in the European Union under E321.
Butylated Hydroxytoluene (BHT) is used as a preservative ingredient in some foods.
With this usage Butylated Hydroxytoluene (BHT) maintains freshness or prevents spoilage; it may be used to decrease the rate at which the texture, color, or flavor of food changes.
Some food companies have voluntarily eliminated Butylated Hydroxytoluene (BHT) from their products or have announced that they were going to phase it out.
-Preservative uses of Butylated Hydroxytoluene (BHT):
Due to its ability to prevent oxidative deterioration, Butylated Hydroxytoluene (BHT) is often used as a preservative in foods containing fats and oils.
Butylated Hydroxytoluene (BHT) is commonly found in snacks, baked goods, cereals, and other processed foods.
Stabilizer in Cosmetics: Butylated Hydroxytoluene (BHT) is used in cosmetics and personal care products, such as lipsticks and lotions, to prevent the oxidation of fats and oils in these formulations.
Pharmaceutical: Butylated Hydroxytoluene (BHT) is also used in some pharmaceuticals to maintain the stability of certain medications by preventing oxidation.
Industrial Uses: Butylated Hydroxytoluene (BHT) finds applications in the rubber and petroleum industries to prevent the degradation of materials exposed to oxygen.
-Antioxidant uses of Butylated Hydroxytoluene (BHT):
Butylated Hydroxytoluene (BHT) is also used as an antioxidant in products such as metalworking fluids, cosmetics, pharmaceuticals, rubber, transformer oils, and embalming fluid.
In the petroleum industry, where Butylated Hydroxytoluene (BHT) is known as the fuel additive AO-29 (Innospec), it is used in hydraulic fluids, turbine and gear oils, and jet fuels.
Butylated Hydroxytoluene (BHT) is also used to prevent peroxide formation in organic ethers and other solvents and laboratory chemicals.
Butylated Hydroxytoluene (BHT) is added to certain monomers as a polymerisation inhibitor to facilitate their safe storage.
Some additive products contain Butylated Hydroxytoluene (BHT) as their primary ingredient, while others contain the chemical merely as a component of their formulation, sometimes alongside butylated hydroxyanisole (BHA).
BENEFITS AND USES of BUTYLATED HYDROXYTOLUENE (BHT):
Butylated Hydroxytoluene (BHT) is chiefly used as an antioxidant food additive and can be found in packaged food items.
Butylated Hydroxytoluene (BHT) is also added to plastics and rubber which is used to store fatty food items.
When added to cosmetics and personal care products, Butylated Hydroxytoluene (BHT) slows down their deterioration and increases their shelf life.
Butylated Hydroxytoluene (BHT) is used in manufacturing eyeliners, lipsticks, blushes, foundation, cleansers, and perfumes.
Butylated Hydroxytoluene (BHT) is widely used to stabilise product formulations.
HOW BUTYLATED HYDROXYTOLUENE (BHT) WORKS:
Butylated Hydroxytoluene (BHT) works by preventing food from going rancid.
Butylated Hydroxytoluene (BHT)'s antioxidant properties fight oxidation in the cells and protect their outer layer from damage.
CONCENTRATION AND SOLUBILITY of BUTYLATED HYDROXYTOLUENE (BHT):
Butylated Hydroxytoluene (BHT)'s optimal concentration level ranges from 0.001% in packaged food products to a maximum of 0.5% in cosmetics.
Butylated Hydroxytoluene (BHT) is soluble in oil and ethanol.
Butylated Hydroxytoluene (BHT) is insoluble in water.
HOW TO USE BUTYLATED HYDROXYTOLUENE (BHT):
Add Butylated Hydroxytoluene (BHT) to the heated oil phase.
Combine Butylated Hydroxytoluene (BHT) with the water phase of the formulation.
Mix and stir continuously until Butylated Hydroxytoluene (BHT) dissolves.
FUNCTIONS (INCI) of BUTYLATED HYDROXYTOLUENE (BHT):
*Antioxidant :
Butylated Hydroxytoluene (BHT) inhibits reactions favored by oxygen, thus avoiding oxidation and rancidity
*Masking :
Butylated Hydroxytoluene (BHT) reduces or inhibits the odor or basic taste of the product
BUTYLATED HYDROXYTOLUENE (BHT) IS PRESENT IN:
Butylated Hydroxytoluene (BHT) is present in 7.4% of cosmetics.
*Razor blades (67.25%)
*Beard trimmer (53.76%)
*Men's eau de cologne (51.22%)
*Men's cologne (48.06%)
*Body razor (46%)
PHYSICAL PROPERTIES of BUTYLATED HYDROXYTOLUENE (BHT):
Butylated Hydroxytoluene (BHT) is typically a white crystalline solid or slightly off-white powder with a faint aromatic odor.
Butylated Hydroxytoluene (BHT) is non-volatile under normal conditions and has good stability at room temperature.
Butylated Hydroxytoluene (BHT) has a melting point in the range of approximately 69–71 °C and does not readily evaporate due to its low vapor pressure.
Butylated Hydroxytoluene (BHT) is practically insoluble in water, but it dissolves easily in organic solvents such as ethanol, methanol, fats, oils, and hydrocarbons.
This lipophilic nature makes Butylated Hydroxytoluene (BHT) highly effective in lipid-rich environments.
Butylated Hydroxytoluene (BHT) is stable under normal storage conditions but may slowly discolor when exposed to light and air over long periods.
CHEMICAL PROPERTIES of BUTYLATED HYDROXYTOLUENE (BHT):
Butylated Hydroxytoluene (BHT) functions as a chain-breaking antioxidant, meaning it donates hydrogen atoms to free radicals formed during lipid oxidation.
This interrupts the oxidative chain reaction and prevents rancidity.
Chemically, Butylated Hydroxytoluene (BHT) is relatively stable, though it can slowly oxidize under strong oxidizing agents or prolonged exposure to heat and oxygen.
Butylated Hydroxytoluene (BHT) is compatible with most organic compounds used in food and industrial formulations.
Butylated Hydroxytoluene (BHT) does not hydrolyze easily and remains stable across a broad pH range in non-aqueous systems.
Butylated Hydroxytoluene (BHT)'s antioxidant efficiency is enhanced by its sterically hindered phenolic structure, where bulky tert-butyl groups stabilize the phenoxyl radical formed after hydrogen donation.
CHARACTERISTICS of BUTYLATED HYDROXYTOLUENE (BHT):
Butylated Hydroxytoluene (BHT) is characterized by strong antioxidant activity, high lipid solubility, and excellent stability in fats and oils.
Butylated Hydroxytoluene (BHT) is effective at very low concentrations, making it economically efficient.
Butylated Hydroxytoluene (BHT) is also often used in combination with other antioxidants such as BHA or citric acid to improve overall preservation performance.
Butylated Hydroxytoluene (BHT) is synthetic in origin and does not naturally occur in significant quantities in foods.
Butylated Hydroxytoluene (BHT)'s performance is especially important in preventing rancidity in products containing unsaturated fats.
BUTYLATED HYDROXYTOLUENE (BHT) CAN BE FOUND IN:
Butylated Hydroxytoluene (BHT) can also be found in a variety of products available to consumers, including:
*cosmetics
*fabrics and textiles
*plastics and rubber
*lubricants and fuels
*paints and coatings
*non-prescription drugs
*adhesives and sealants
*natural health products
People are exposed to Butylated Hydroxytoluene (BHT) through:
*drinking water
*food and food packaging materials
*products available to consumers, such as:
*paints
*lubricants
*cosmetics
*plastics and rubber
*automotive products
Butylated Hydroxytoluene (BHT) is part of a group of substances called substituted phenols.
ALTERNATIVE PARENTS of BUTYLATED HYDROXYTOLUENE (BHT):
*Para cresols
*Toluenes
*Organooxygen compounds
*Hydrocarbon derivatives
SUBSTITUENTS of BUTYLATED HYDROXYTOLUENE (BHT):
*Phenylpropane
*P-cresol
*Toluene
*Phenol
*Organic oxygen compound
*Hydrocarbon derivative
*Organooxygen compound
*Aromatic homomonocyclic compound
WHAT IS BUTYLATED HYDROXYTOLUENE (BHT) USED FOR?
Butylated Hydroxytoluene (BHT) is mainly used as an antioxidant to prevent the spoilage of cosmetic formulations, particularly those that contain oil or fats in a water base.
Butylated Hydroxytoluene (BHT) is used in various cosmetic products that are aqueous in nature and contain active ingredients or plant extracts.
Butylated Hydroxytoluene (BHT) resists high temperatures and stabilizes the raw materials themselves and is also used in the manufacturing process of raw materials.
Butylated Hydroxytoluene (BHT) is often used at concentrations ranging from 0.0001% to 0.5%.
*Skin care:
Butylated Hydroxytoluene (BHT) enhances the shelf-life of skin care products by preventing oxidation.
Butylated Hydroxytoluene (BHT) also functions as a synthetic analog of vitamin E.
Similar to vitamin E, Butylated Hydroxytoluene (BHT) prevents autoxidation, where the unsaturated organic compounds in a cosmetic formulation may be attacked by oxygen changing their color, texture, or efficacy
ORIGIN of BUTYLATED HYDROXYTOLUENE (BHT):
Butylated Hydroxytoluene (BHT) is produced by the reaction of p-cresol with isobutylene and sulfuric acid.
WHAT DOES BUTYLATED HYDROXYTOLUENE (BHT) DO IN A FORMULATION?
*ANTIOXIDANT
*MASKING
SAFETY PROFILE of BUTYLATED HYDROXYTOLUENE (BHT):
Butylated Hydroxytoluene (BHT) has been considered as safe for use in cosmetics by the Cosmetic Ingredient Review (CIR) board.
ALTERNATIVES of BUTYLATED HYDROXYTOLUENE (BHT):
*TOCOPHEROL
PRODUCTION OF BUTYLATED HYDROXYTOLUENE (BHT):
Industrial production;
The chemical synthesis of Butylated Hydroxytoluene (BHT) in industry has involved the reaction of p-cresol (4-methylphenol) with isobutylene (2-methylpropene), catalyzed by sulfuric acid:
CH3(C6H4)OH + 2 CH2=C(CH3)2 → ((CH3)3C)2CH3C6H2OH
Alternatively, Butylated Hydroxytoluene (BHT) has been prepared from 2,6-di-tert-butylphenol by hydroxymethylation or aminomethylation followed by hydrogenolysis.
REACTIONS OF BUTYLATED HYDROXYTOLUENE (BHT):
The species behaves as a synthetic analog of vitamin E, primarily acting as a terminating agent that suppresses autoxidation, a process whereby unsaturated (usually) organic compounds are attacked by atmospheric oxygen.
Butylated Hydroxytoluene (BHT) stops this autocatalytic reaction by converting peroxy radicals to hydroperoxides.
Butylated Hydroxytoluene (BHT) effects this function by donating a hydrogen atom:
RO2• + ArOH → ROOH + ArO•
RO2• + ArO• → nonradical products
where R is alkyl or aryl, and where ArOH is Butylated Hydroxytoluene (BHT) or related phenolic antioxidants.
Each Butylated Hydroxytoluene (BHT) consumes two peroxy radicals.
The electron-donating alkyl groups on the ortho and para positions of Butylated Hydroxytoluene (BHT) increase the electron density of the phenolic hydroxyl moiety through the inductive effect and the hyperconjugation effect, reduce the bond dissociation energy of the phenolic hydroxyl group, and enhance its reactivity to lipid free radicals.
Meanwhile, the phenoxy radical generated by Butylated Hydroxytoluene (BHT) is stabilized due to the delocalization of unpaired electrons around the aromatic ring and the steric hindrance effect of ortho tert-butyl groups.
Isobutene is one of the possible degradation products formed by Butylated Hydroxytoluene (BHT) oxidation with computational studies suggesting that there are two possible mechanisms that can lead to isobutene formation, with the OH addition pathways at the C2 site of Butylated Hydroxytoluene (BHT) more likely to result in isobutene formation than pathways of H abstracts from the t-butyl group.
INDUSTRIES of BUTYLATED HYDROXYTOLUENE (BHT):
*Food & Beverage
*Personal Care & Cosmetics
*Pharmaceutical & Nutraceutical
*Agriculture
SOURCES of BUTYLATED HYDROXYTOLUENE (BHT):
Instead of being added directly to the food itself, Butylated Hydroxytoluene (BHT) is usually added to the packaging material from where it can vaporize into the food during storage.
Since Butylated Hydroxytoluene (BHT) may be classified as an incidental food additive when used in this manner, it does not legally need to be listed with other ingredients on the food label.
Processed foods most likely to feature Butylated Hydroxytoluene (BHT) include chewing gum, active dry yeast, frozen convenience foods, prepared cereal products, prepared snacks, dried and processed meat, potato flakes, enriched rice products and shortening.
Butylated Hydroxytoluene (BHT) is also a chemical preservative used in animal feeds and drugs; therefore consumption of non-organic meats and dairy products may be another vector for exposure.
In addition to its use in food preservation, BHA is also used in the manufacture of rubber, tires and petroleum and is an ingredient in some cosmetics.
HOW DOES BUTYLATED HYDROXYTOLUENE (BHT) WORK ?
Butylated Hydroxytoluene (BHT) is an antioxidant.
Butylated Hydroxytoluene (BHT) may damage the protective outer layer of viral cells.
This may keep the viruses from multiplying and/or doing more damage.
USES & EFFECTIVENESS of BUTYLATED HYDROXYTOLUENE (BHT):
Insufficient Evidence for
Cold sores caused by a type of virus called herpes.
Developing evidence suggests that putting Butylated Hydroxytoluene (BHT) on cold sores may help them heal faster.
Genital herpes.
Acquired immunodeficiency syndrome (AIDS).
Other conditions.
More evidence is needed to rate the effectiveness of Butylated Hydroxytoluene (BHT) for these uses.
BENEFITS of BUTYLATED HYDROXYTOLUENE (BHT):
Butylated Hydroxytoluene (BHT) provides several functional benefits, including extending the shelf life of consumable and non-consumable products, preventing rancid odors and taste deterioration, and preserving the chemical integrity of fats and oils.
Butylated Hydroxytoluene (BHT) improves product stability under storage conditions and reduces economic losses due to spoilage.
Its high effectiveness at low concentrations makes Butylated Hydroxytoluene (BHT) a cost-efficient additive.
Butylated Hydroxytoluene (BHT) is a highly effective synthetic antioxidant designed to prevent oxidative degradation in fats, oils, and lipid-containing systems.
Its strong radical-scavenging ability, chemical stability, and compatibility with organic materials make Butylated Hydroxytoluene (BHT) a key additive in food preservation, cosmetics, pharmaceuticals, and industrial formulations.
PHYSICAL and CHEMICAL PROPERTIES of BUTYLATED HYDROXYTOLUENE (BHT):
Appearance Form: Crystalline powder
Color: colorless
Odor: odorless
Odor Threshold: Not applicable
Molecular Weight: 220.35
Purity >99%
pH: No data available
Melting point/freezing point: Melting point/range: 69 - 73 °C - lit.
Initial boiling point and boiling range: 265 °C - lit
Flash point: No data available
Evaporation rate: No data available
Flammability (solid, gas): No data available
Upper/lower flammability or explosive limits: No data available
Vapor pressure: 0,00 hPa at 25 °C
Vapor density: No data available
Relative density: 1,03 g/cm3 at 20 °C -
Water solubility: 0,76 g/l at 20 °C
Partition coefficient n-octanol/water: log Pow: 5,1
Autoignition temperature: > 400 °C
Decomposition temperature: No data available
Viscosity: No data available
Explosive properties: No data available
Oxidizing properties: No data available
Typical range of impurities: ≤ 10 ppm heavy metals and ≤3 ppm arsenic
Solubility:
0.4 mg/L in water at 20 °C
0.6 mg/L in water at 25 °C
1.5 mg/L at 30 ºC and 6 mg/L at 60 ºC
Freely soluble in toluene
55.9 wt% in n-heptane at 29.5 °C
34 wt% in ethanol at 28.7 °C
31.1 wt% in 1-octanol at 29.5 °C
0.5% w/w in methanol, isopropanol, methyl ethyl ketone, acetone, cellosolve, benzene,
Most hydrocarbon solvents, ethanol, petroleum ether,
liquid petrolatum (white oil), good solubility in linseed oil.
Insoluble in propylene glycol
Melting point: 70-71 °C
Boiling point: 265 °C at 760 mm Hg
Flash point: 127 °C
Vapour pressure: 0.01 mm Hg, 0.005 mm Hg at 25 °C, 0.39 Pa at 25 °C
Density: 0.899 (g/mL)
Viscosity:
3.47 centistokes at 0 °C
1.54 centistokes at 120 °C
pKa: 14, 12.2 at 20 °C
refractive index: 1.49 at 75 °C
topical polar surface area: 20.2 Å2
Appearance Form: powder, crystalline
Color: colorless
Odor: odorless
Odor Threshold: Not applicable
pH: No data available
Melting point/range: 69 - 73 °C - lit.
Initial boiling point and boiling range: 265 °C - lit.
Flash point: 127 °C
Evaporation rate: No data available
Flammability (solid, gas): No data available
Upper/lower flammability or explosive limits :No data available
Vapor pressure 0,00 hPa at 25 °C
Vapor density: No data available
Relative density: No data available
Water solubility 0,76 g/l at 20 °C
Partition coefficient: n-octanol/water log Pow: 5,1
Autoignition temperature: > 400 °C
Decomposition temperature: No data available
Viscosity:
*Viscosity, kinematic: No data available
*Viscosity, dynamic: No data available
Boiling point: 265 °C (1013 hPa)
Density:1.03 g/cm3 (20 °C)
Ignition temperature: 345 °C
Vapor pressure:0.39 Pa (298 K)
Bulk density: 450 kg/m3
Solubility: <0.001 g/l
Water Solubility: 0.015 g/L
logP: 5.25
logP: 5.27
logS: -4.2
pKa (Strongest Acidic): 11.6
pKa (Strongest Basic): -4.6
Physiological Charge: 0
Hydrogen Acceptor Count: 1
Hydrogen Donor Count: 1
Polar Surface Area: 20.23 Ų
Rotatable Bond Count: 2
Refractivity: 70.41 m³·mol⁻¹
Polarizability: 27.35 ų
Number of Rings: 1
Bioavailability: Yes
Rule of Five: No
Ghose Filter: Yes
Veber's Rule: Yes
MDDR-like Rule: No
CAS number: 128-37-0
EC number: 204-881-4
Grade: E 321
Hill Formula: C₁₅H₂₄O
Molar Mass: 220.36 g/mol
HS Code: 2907 19 90
Chemical Formula: C₁₅H₂₄O
Molecular Weight: 220.35 g/mol
CAS Number: 128-37-0
Boiling point: 265 °C (1013 hPa)
Density: 1.03 g/cm3 (20 °C)
Flash point: 127 °C
Ignition temperature: 345 °C
Melting Point: 69.8 °C 1
Vapor pressure: 0.39 Pa (298 K)
Bulk density: 450 kg/m3
Solubility: <0.001 g/l
Appearance: White to yellowish crystalline powder
Solubility: Insoluble in water, but soluble in ethanol, methanol, and propylene glycol
Appearance: White crystalline powder or flake, odorless or with a characteristic faint aromatic odor
Other names: Butylhydroxytoluene, 2,6-ditertiary-butyl-p-cresol, 4-methyl-2,6-ditertiarybutylphenol 2
CAS number: 128-37-0
Chemical formula: C15H24O
Molecular weight: 220.36
Solubility: Insoluble in water, freely soluble in food fats and oils 3
Chemical formula: C15H24O
Molar mass: 220.356 g/mol
Appearance: White to yellow powder
Odor: Slight, phenolic
Density: 1.048 g/cm3
Melting point: 70 °C (158 °F; 343 K)
Boiling point: 265 °C (509 °F; 538 K)
Solubility in water: 1.1 mg/L (20 °C)
log P: 5.32
Vapor pressure: 0.01 mmHg (20 °C)
Product Name: BHT-Butyl Hydroxy Toluene (E 321)
Chemical Formula: C15H24O
Cas No: 128-37-0
EINESC No: 204-881-4
UN No: 3077
Physical Property: White Solid Crystal
Odor: Odorless
Molecular Weight: 220.4 g/mol
Density: 1.03 g/cm3
Solubility: Slightly soluble in water
Empirical Formula (Hill Notation): C15H24O
CAS Number: 128-37-0
Molecular Weight: 220.35
MDL number: MFCD00011644
UNSPSC Code: 12352104
E Number: E321
EC Index Number: 204-881-4
Physical state: crystalline
Color: white
Odor: odorless
Melting point/freezing point:
Melting point: 69,8 °C
Initial boiling point and boiling range:
265 °C at 1.013 hPa
Flammability (solid, gas): No data available
Upper/lower flammability or explosive limits: No data available
Flash point: 127 °C - open cup
Autoignition temperature: > 400 °C
Decomposition temperature: No data available
pH: No data available
Viscosity:
Viscosity, kinematic: No data available
Viscosity, dynamic: No data available
Water solubility: 0,76 g/l at 20 °C - slightly soluble
Partition coefficient: n-octanol/water:
log Pow: 5,1 - - Potential bioaccumulation, (ECHA)
Vapor pressure: 0,00 hPa at 25 °C
Density: 1,03 g/cm3 at 20 °C
Relative density: No data available
Relative vapor density: No data available
Particle characteristics: No data available
Explosive properties: Not classified as explosive.
Oxidizing properties: none
Other safety information:
Bulk density: 450 kg/m3
Other(deleted CASRN):102962-45-8
ECHA EINECS - REACH Pre-Reg:204-881-4
FDA UNII:1P9D0Z171K
Nikkaji Web:J2.939D
Beilstein Number:1911640
MDL:MFCD00011644
XlogP3-AA:5.30 (est)
Molecular Weight:220.35548000
Formula:C15 H24 O
Appearance:White to light yellow crystalline solid/powder
Odor:Slight phenolic odor
Density:~1.048 g/cm³
Melting Point:~69-73 °C
Boiling Point:~265 °C
Flash Point:~127 °C (varies with test method)
Water Solubility:Very low (≈ 1.1 mg/L @ 20 °C)
Solubility:Soluble in organic solvents (methanol, ethanol, oils)
log P:~5.32 (lipophilic)
Vapor Pressure:Very low (~0.01 mmHg @ 20 °C)
Common Name:Butylated Hydroxy Toluene
Abbreviation:BHT
CAS Number:128-37-0
EC Number:204-881-4
Chemical Formula:C₁₅H₂₄O
Molar Mass:~220.36 g/mol
IUPAC Name:2,6-Di-tert-butyl-4-methylphenol
Appearance:colorless crystals (est)
Assay:95.00 to 100.00
Food Chemicals Codex Listed:Yes
Melting Point:70.00 to 73.00 °C. @ 760.00 mm Hg
Boiling Point:265.00 °C. @ 760.00 mm Hg
Vapor Pressure:15.000000 mmHg @ 141.00 °C.
Vapor Density:7.6 ( Air = 1 )
Flash Point:> 200.00 °F. TCC ( > 93.33 °C. )
logP (o/w):5.100
Soluble in:alcohol;water, 0.6 mg/L @ 25 °C (exp)
FIRST AID MEASURES of BUTYLATED HYDROXYTOLUENE (BHT):
-If inhaled:
*After inhalation:
Fresh air.
-In case of skin contact:
Rinse skin with water/ shower.
-In case of eye contact:
*After eye contact:
Rinse out with plenty of water.
Remove contact lenses.
-If swallowed:
*After swallowing:
Make victim drink water (two glasses at most).
Consult doctor if feeling unwell.
ACCIDENTAL RELEASE MEASURES of BUTYLATED HYDROXYTOLUENE (BHT):
-Environmental precautions
Do not let product enter drains.
-Methods and materials for containment and cleaning up:
Cover drains.
Collect, bind, and pump off spills.
Take up dry.
Dispose of properly.
FIRE FIGHTING MEASURES of BUTYLATED HYDROXYTOLUENE (BHT):
-Extinguishing media:
*Suitable extinguishing media:
Water
Foam
Carbon dioxide (CO2)
Dry powder
*Unsuitable extinguishing media:
For this substance/mixture no limitations of extinguishing agents are given.
-Further information:
Prevent fire extinguishing water from contaminating surface water or the ground water system.
EXPOSURE CONTROLS/PERSONAL PROTECTION of BUTYLATED HYDROXYTOLUENE (BHT):
-Control parameters:
*Ingredients with workplace control parameters:
-Exposure controls:
--Personal protective equipment:
*Eye/face protection:
Use safety glasses
*Skin protection:
Full contact:
Material: Nitrile rubber
Minimum layer thickness: 0,11 mm
Break through time: 480 min
Splash contact:
Material: Nitrile rubber
Minimum layer thickness: 0,11 mm
Break through time: 480 min
-Control of environmental exposure:
Do not let product enter drains.
HANDLING and STORAGE of BUTYLATED HYDROXYTOLUENE (BHT):
-Conditions for safe storage, including any incompatibilities:
*Storage conditions:
Dry.
Tightly closed.
-Specific end use(s):
No other specific uses are stipulated
STABILITY and REACTIVITY of BUTYLATED HYDROXYTOLUENE (BHT):
-Chemical stability:
The product is chemically stable under standard ambient conditions (room temperature).