C14 MYRISTIC ACID

CAS Number : 544-63-8
EC  Number : 208-875-2
Molecular Formula :     C14H28O2
Molecular Weight  :  228.37
Melting point      :  54.4 °C
Boiling point      :  326.2 °C

C14 Myristic Acid  (IUPAC name: tetradecanoic acid) is a common saturated fatty acid with the molecular formula CH3(CH2)12COOH. 
Its salts and esters are commonly referred to as myristates or tetradecanoates. 
C14 Myristic Acid  is named after the binomial name for nutmeg (Myristica fragrans), from which it was first isolated in 1841 by Lyon Playfair.

Occurrence of C14 Myristic Acid
Nutmeg butter has 75% trimyristin, the triglyceride of myristic acid. 
Besides nutmeg, myristic acid is found in palm kernel oil, coconut oil, butterfat, 8–14% of bovine milk, and 8.6% of breast milk as well as being a minor component of many other animal fats.
C14 Myristic Acid is found in spermaceti, the crystallized fraction of oil from the sperm whale. 
C14 Myristic Acid is also found in the rhizomes of the Iris, including Orris root.

C14 Myristic Acid is a saturated long-chain fatty acid with a 14-carbon backbone. 
C14 Myristic Acid is found naturally in palm oil, coconut oil and butter fat.

Use and Manufacturing of C14 Myristic Acid
Found in most animal and vegetable fats; [Merck Index] Used as a flavor and fragrance in food, soaps, shaving creams, perfumes, and cosmetics; Also used in lubricants and coatings for anodized aluminum
C14 Myristic Acid is used in the food industry as a flavor ingredient. 
C14 Myristic Acid is found widely distributed in fats throughout the plant and animal kingdom, including common human foodstuffs, such as nutmeg.

Soaps, cosmetics, synthesis of esters for flavors and perfumes, component of food-grade additives.
This is an endogenously produced metabolite found in the human body. It is used in metabolic reactions, catabolic reactions or waste generation.

Industry Uses of C14 Myristic Acid
-Adhesives and sealant chemicals
-Emulsifier
-Finishing agents
-Fuel
-Intermediate
-Lubricants and lubricant additives
-Lubricating agent
-Not Known or Reasonably Ascertainable
-Opacifer
-Other (specify)
-Paint additives and coating additives not described by other categories
-Plating agents and surface treating agents
-Processing aids not otherwise specified
-Processing aids, not otherwise listed
-Surface active agents
-Surfactant (surface active agent)

Consumer Uses of C14 Myristic Acid
-Adhesives and sealant chemicals
-Agricultural chemicals (non-pesticidal)
-Emulsifier
-Flavoring and nutrient
-Lubricants and lubricant additives
-Lubricating agent
-Not Known or Reasonably Ascertainable
-Opacifer
-Other (specify)
-Paint additives and coating additives not described by other categories
-Plating agents and surface treating agents
-Processing aids, not otherwise listed
-Surfactant (surface active agent)

Household Products
Household & Commercial/Institutional Products
Information on 39 consumer products that contain Myristic acid in the following categories is provided:
-Commercial / Institutional
-Inside the Home
-Personal Care

General Manufacturing Information    
Industry Processing Sectors
-Adhesive Manufacturing
-All Other Basic Organic Chemical Manufacturing
-All Other Chemical Product and Preparation Manufacturing
-Food, beverage, and tobacco product manufacturing
-Miscellaneous Manufacturing
-Not Known or Reasonably Ascertainable
-Other (requires additional information)
-Paper Manufacturing
-Petroleum Lubricating Oil and Grease Manufacturing
-Plastics Material and Resin Manufacturing
-Plastics Product Manufacturing
-Soap, Cleaning Compound, and Toilet Preparation Manufacturing
-Textiles, apparel, and leather manufacturing
-Wholesale and Retail Trade

C14 Myristic Acid — also known as tetradecanoic acid — is a saturated fatty acid with 14 carbon atoms that has many industrial applications. 
C14 Myristic Acid is a minimum 98-percent pure and obtained wholly from vegetable-based (palm oil) sources. 

Uses & Applications of C14 Myristic Acid

C14 Myristic Acid has a wide range of uses in various industries and manufacturing processes. 
You can find it in foods and beverages, in which it is used as a flow agent and emulsifier. 
C14 Myristic Acid is a surfactant in soaps, detergents and textiles, as well as an intermediate, internal or external lubricant in plastics. 
C14 Myristic Acid, an ester of myristic acid, is used in the preparation of pharmaceuticals, cosmetics and personal care products to promote absorption through the skin.

Usage Areas of C14 Myristic Acid
Surfactants and Esters: Anionic and Nonionic Surfactants for Chemicals, Textiles, Food, Soap & Detergent
Food and Beverage: Flow Agent and Emulsifier
Plastics: Intermediate, Internal and External Lubricant
Soaps and Detergents: Anionic/Nonionic Surfactants
Textiles: Anionic/Nonionic Surfactants
Personal Care: Emulsifier for Facial Creams and Lotions

 
Specifications of C14 Myristic Acid
 
Appearance (Colour)    : White
Appearance (Colour)    : White
Appearance (Form)    : Crystalline powder
Appearance (Form)    : Crystalline powder/Flakes
Assay                    : min. 99%
Assay (GC-C14)            : min. 99%

C14 Myristic Acid, also called tetradecanoic acid or 14:0 is a common saturated fatty acid with the molecular formula CH3(CH2)12COOH. 
A myristate is a salt or ester of myristic acid.
C14 Myristic Acid is named after the nutmeg Myristica fragrans. 
Nutmeg butter is 75% trimyristin, the triglyceride of myristic acid. 
Besides nutmeg, C14 Myristic Acid is also found in palm kernel oil, coconut oil, butter fat and is a minor component of many other animal fats. 
C14 Myristic Acid is also found in spermacetin, the crystallized fraction of oil from the sperm whale.

C14 Myristic Acid is also commonly added co-translationally to the penultimate, nitrogen-terminus, glycine in receptor-associated kinases to confer the membrane localisation of the enzyme. The C14 Myristic Acid has a sufficiently high hydrophobicity to become incorporated into the fatty acyl core of the phospholipid bilayer of the plasma membrane of the eukaryotic cell. 
In this way, C14 Myristic Acid acts as a lipid anchor in biomembranes.

C14 Myristic Acid, a common saturated fatty acid found in nutmeg, palm kernel oil, coconut oil and butter fat, has been evaluated as a penetration enhancer in rat melatonin transdermal patches and bupropion preparations on human cadaver skin.
C14 Myristic Acid, also called tetradecanoic acid, occurs naturally in vegetable or animal fats and oils with relatively high levels found in nutmeg, palm oil, coconut oil and butter  fat. The salts of C14 Myristic Acid are formed by reaction with base materials such as sodium or potassium hydroxide. 
The esters of C14 Myristic Acid are derived from Myristic Acid and an alcohol .

C14 Myristic Acid is most commonly used in eye makeup, moisturizers,  soaps and detergents, hair care products, nail care products, shaving products, and other skincare products. 
C14 Myristic Acid is typically used at concentrations of 1 to 10%. 
C14 Myristic Acid is mainly used to help improve the texture of skincare and cosmetic products but also has the added benefit of helping to moisturize the skin. 
C14 Myristic Acid is not a particularly active ingredient, apart from adding moisture it does little else for the skin. 
All skin types except those that have an identified allergy to it. 
Works well with most ingredients. 
Nothing to keep an eye on here, C14 Myristic Acid is safe and doesn’t cause irritation. 
In cosmetics and skincare products, C14 Myristic Acid functions as an emollient, texture enhancer, and moisturizer.

C14 Myristic Acid is used as a moisturizer in formulations. 
As an emollient C14 Myristic Acid works to soften and soothe the skin and hair. 
Emollients work but forming a protective barrier on the surface of the skin. 
This action helps to trap water in the top few layers of the skin, improving the skin barrier integrity. 
The skin barrier is the first few layers of the skin and the natural oils that the skin produces that protect the skin from bacteria, allergens, and prevents water loss to the environment. These same properties also help to keep the hair soft, hydrated, and manageable. 

C14 Myristic Acid also functions to improve the texture of formulations. 
C14 Myristic Acid helps to improve the spreadability of a product, making sure that the product evenly distributes the key ingredients. 
In certain soap formulations, an excess of C14 Myristic Acid produces pearl effects giving the skin a glossy appearance. 
C14 Myristic Acid reduces the watery feel of hand and body lotions and imparts a richness in the sensory feel of the products. 
Interestingly, the addition of C14 Myristic Acid to an emulsion can take it from dull gray to bright white, making the product look more appealing. 

C14 Myristic Acid will also impart a very pleasant soft powdery feel on the skin. 
This is a great addition to your formulas when your final product does not deliver a nice feel on the skin or leaves the skin feeling too greasy. 
By adding C14 Myristic Acid you can keep your oil and butter levels higher and still avoid the unpleasant greasiness.

First Aid Measures of C14 Myristic Acid

EYES: 
First check the victim for contact lenses and remove if present. 
Flush victim's eyes with water or normal saline solution for 20 to 30 minutes while simultaneously calling a hospital or poison control center. 
Do not put any ointments, oils, or medication in the victim's eyes without specific instructions from a physician. 
IMMEDIATELY transport the victim after flushing eyes to a hospital even if no symptoms (such as redness or irritation) develop.

SKIN: 
IMMEDIATELY flood affected skin with water while removing and isolating all contaminated clothing. 
Gently wash all affected skin areas thoroughly with soap and water. 
If symptoms such as redness or irritation develop, IMMEDIATELY call a physician and be prepared to transport the victim to a hospital for treatment.

INHALATION: 
IMMEDIATELY leave the contaminated area; take deep breaths of fresh air. 
If symptoms (such as wheezing, coughing, shortness of breath, or burning in the mouth, throat, or chest) develop, call a physician and be prepared to transport the victim to a hospital. Provide proper respiratory protection to rescuers entering an unknown atmosphere. 
Whenever possible, Self-Contained Breathing Apparatus (SCBA) should be used; if not available, use a level of protection greater than or equal to that advised under Protective Clothing.

INGESTION: 
DO NOT INDUCE VOMITING. 
If the victim is conscious and not convulsing, give 1 or 2 glasses of water to dilute the chemical and IMMEDIATELY call a hospital or poison control center. 
Be prepared to transport the victim to a hospital if advised by a physician. 
If the victim is convulsing or unconscious, do not give anything by mouth, ensure that the victim's airway is open and lay the victim on his/her side with the head lower than the body. 
DO NOT INDUCE VOMITING. 
IMMEDIATELY transport the victim to a hospital.

Handling and Storage of C14 Myristic Acid

SMALL SPILLS AND LEAKAGE: 
Should a spill occur while you are handling this chemical, FIRST REMOVE ALL SOURCES OF IGNITION, then you should dampen the solid spill material with 60-70% ethanol and transfer the dampened material to a suitable container. 
Use absorbent paper dampened with 60-70% ethanol to pick up any remaining material. 
Seal the absorbent paper, and any of your clothes, which may be contaminated, in a vapor-tight plastic bag for eventual disposal. 
Solvent wash all contaminated surfaces with 60-70% ethanol followed by washing with a soap and water solution. 
Do not reenter the contaminated area until the Safety Officer (or other responsible person) has verified that the area has been properly cleaned.

STORAGE PRECAUTIONS:
You should store this material in a refrigerator. 
STORE AWAY FROM SOURCES OF IGNITION.

Substance identity

EC / List no.: 208-875-2
CAS no.: 544-63-8
Mol. formula: C14H28O2

Hazard classification & labelling of C14 Myristic Acid  
Warning! According to the classification provided by companies to ECHA in CLP notifications this substance causes serious eye irritation and causes skin irritation.

C14 Myristic Acid  predicted as likely to meet criteria for category 1A or 1B carcinogenicity, mutagenicity, or reproductive toxicity, or with dispersive or diffuse use(s) where predicted likely to meet any classification criterion for health or environmental hazards, or where there is a nanoform soluble in biological and environmental media.
C14 Myristic Acid  indicated, in 2009, as being intended to be registered by at least one company in the EEA.

C14 Myristic Acid for which classification and labeling data have been submitted to ECHA in a registration under REACH or notified by manufacturers or importers under CLP. 
Such notifications are required for hazardous substances, as such or in mixtures, as well as for all substances subject to registration, regardless of their hazard.
C14 Myristic Acid listed in the EINECS, ELINCS, or NLP inventories.

Synonyms:
1-Tridecanecarboxylic acid
C14 fatty acid
Crodacid
Emery 655
Hydrofol acid 1495
Hystrene 9014
Myristic acid
Myristic acid
myristic acid
Myristic acid (natural)
Myristic acid, pure
n-Tetradecan-1-oic acid
n-Tetradecanoic acid
n-Tetradecoic acid
Neo-fat 14
Univol U 316S
MYRISTIC ACID
Myristic Acid
Myristic acid
myristic acid
N-tetradecan-1-oic acid
Tetradecanoic acid
tetradecanoic acid
45184-05-2
544-63-8
Tetradecanoic acid
MYRISTIC ACID
544-63-8
n-Tetradecanoic acid
n-Tetradecan-1-oic acid
Crodacid
n-Tetradecoic acid
1-Tridecanecarboxylic acid
Myristate
tetradecoic acid
Hydrofol acid 1495
Univol U 316S
Emery 655
Myristinsaeure
Hystrene 9014
Neo-fat 14
C14 fatty acid
FEMA No. 2764
Myristic acid, pure
n-Myristic acid
Myristic acid (natural)
Tetradecanoate
acide tetradecanoique
NSC 5028
CCRIS 4724
CH3-[CH2]12-COOH
HSDB 5686
C14:0
Philacid 1400
CHEBI:28875
AI3-15381
Prifac 2942
NSC-5028
1-tetradecanecarboxylic acid
PHILACID-1400
PRIFRAC-2942
0I3V7S25AW
CHEMBL111077
NSC5028
DSSTox_CID_1666
n-tetradecan-1-oate
DSSTox_RID_76274
DSSTox_GSID_21666
32112-52-0
CAS-544-63-8
Myristic acid [NF]
EINECS 208-875-2
BRN 0508624
myristoate
UNII-0I3V7S25AW
myristoic acid
n-Tetradecanoate
Tetradecanoicacid
3usx
Myristic acid pure
Myristic Acid Flake
MFCD00002744
Hystrene 9514
Edenor C 14
Myristic Acid 655
1-Tridecanecarboxylate
MAGNESIUMARSENATE
Myristic acid, 95%
Myristic acid, natural
tridecanecarboxylic acid
Myristic acid (8CI)
Myristic Acid, Reagent
3v2n
3w9k
Myristic acid, puriss.
Tetradecanoic acid (9CI)
bmse000737
Epitope ID:176772
MYRISTIC ACID [II]
MYRISTIC ACID [MI]
SCHEMBL6374
MYRISTIC ACID [FCC]
Myristic acid-[14-13C]
MYRISTIC ACID [FHFI]
MYRISTIC ACID [HSDB]
MYRISTIC ACID [INCI]
4-02-00-01126 (Beilstein Handbook Reference)
MLS002152942
WLN: QV13
Tetradecanoic (Myristic) acid
MYRISTIC ACID [MART.]
GTPL2806
MYRISTIC ACID [USP-RS]
DTXSID6021666
HMS3039E15
HMS3648O20
Myristic acid, analytical standard
HY-N2041
ZINC1530417
EINECS 250-924-5
Myristic acid, >=98.0% (GC)
Tox21_201852
Tox21_302781
BDBM50147581
LMFA01010014
s5617
STL185697
Myristic acid, >=95%, FCC, FG
Myristic acid, Sigma Grade, >=99%
AKOS009156714
CCG-266785
DB08231
DS-3833
FA 14:0
NSC 122834
NCGC00091068-01
NCGC00091068-02
NCGC00091068-03
NCGC00256547-01
NCGC00259401-01
AC-34674
BP-27915
SMR001224536
CS-0018531
FT-0602832
FT-0770860
M0476
EN300-78099
C06424
Myristic acid, Vetec(TM) reagent grade, 98%
Q422658
SR-01000854525
SR-01000854525-3
W-109088
F8889-5016
Z1954802504
EDAE4876-C383-4AD4-A419-10C0550931DB
MYRISTIC ACID (CONSTITUENT OF SAW PALMETTO) [DSC]
Myristic acid, United States Pharmacopeia (USP) Reference Standard
Tetradecanoic acid; 1-Tridecanecarboxylic acid; n-Tetradecanoic acid
Myristic acid, Pharmaceutical Secondary Standard; Certified Reference Material
1-tetradecanoic acid
1-Tridecanecarboxylic acid
208-875-2 [EINECS]
508624 [Beilstein]
544-63-8 [RN]
Acide myristique [French] [ACD/IUPAC Name]
Acide tétradécanoïque [French]
myristic acid [ACD/IUPAC Name]
Myristinsäure [German] [ACD/IUPAC Name]
n-Myristic acid
n-TETRADECANOIC ACID
Tetradecanoic acid [ACD/Index Name]
1-Tridecanecarboxylate
n-Tetradecan-1-oate
n-Tetradecanoate
1112209-40-1 [RN]
1114809-17-4 [RN]
12-O-Tetradecanoylphorbol 13-acetate
12-Tetradecanoylphorbol 13-acetate
13-Tetradecynoic acid [ACD/Index Name] [ACD/IUPAC Name]
1-tetradecanecarboxylate
1-tetradecanecarboxylic acid
4-02-00-01126 [Beilstein]
82909-47-5 [RN]
Crodacid
DS-3833
Methyl 11-methyldodecanoate [ACD/IUPAC Name]
Myristic Acid 655
Myristinsaeure
Myristoate
Myristoic acid
n-Tetradecan-1-oic acid
n-tetradecoate
n-Tetradecoic acid
QV13 [WLN]
tetradecanoate
Tetradecanoic-12-d1 Acid
Tetradecanoic-13,13,14,14,14-d5 Acid
TetradecanoicAcid
tetradecoate
tetradecoic acid