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CAS NO:67-97-0
EC NO:200-673-2
Calciferol is vitamin D2.
Calciferol is used to treat hypoparathyroidism.
Calciferol is also used to treat rickets (softening of the bones caused by vitamin D deficiency) or low levels of phosphate in the blood (hypophosphatemia).
Calciferol, also known as vitamin D3 and colecalciferol, is a type of vitamin D which is made by the skin when exposed to sunlight;
it is also found in some foods and can be taken as a dietary supplement.
Calciferol is made in the skin following UVB light exposure.
Calciferol is converted in the liver to calcifediol (25-hydroxyvitamin D) which is then converted in the kidney to calcitriol (1,25-dihydroxyvitamin D).One of its actions is to increase the uptake of calcium by the intestines.
Calciferol is found in food such as some fish, beef liver, eggs, and cheese. Certain foods such as milk, fruit juice, yogurt, and margarine also may have cholecalciferol added to them in some countries including the United States.
Chemical and physical data
Formula C27H44O
Molar mass 384.648 g·mol−1
3D model (JSmol)
Interactive image
Melting point 83 to 86 °C (181 to 187 °F)
Boiling point 496.4 °C (925.5 °F)
Calciferol can be taken as an oral dietary supplement to prevent vitamin D deficiency or as a medication to treat associated diseases, including rickets.
Calciferol is also used for familial hypophosphatemia, hypoparathyroidism that is causing low blood calcium, and Fanconi syndrome. Vitamin-D supplements may not be effective in people with severe kidney disease.
Calciferol (ergocalciferol) is vitamin D2 used to treat hypoparathyroidism (decreased functioning of the parathyroid glands), and is also used to treat rickets (softening of the bones caused by vitamin D deficiency) or low levels of phosphate in the blood (hypophosphatemia).
Calciferol is a steroid hormone produced in the skin when exposed to ultraviolet light or obtained from dietary sources. The active form of cholecalciferol, 1,25-dihydroxycholecalciferol (calcitriol) plays an important role in maintaining blood calcium and phosphorus levels and mineralization of bone.
The activated form of cholecalciferol binds to vitamin D receptors and modulates gene expression. This leads to an increase in serum calcium concentrations by increasing intestinal absorption of phosphorus and calcium, promoting distal renal tubular reabsorption of calcium and increasing osteoclastic resorption.
Calciferol in general, is a secosteroid generated in the skin when 7-dehydrocholesterol located there interacts with ultraviolet irradiation - like that commonly found in sunlight.
Calciferol is a natural product found in Cestrum diurnum, Solanum lycopersicum, and other organisms with data available.
Calciferol is a steroid hormone that principally plays roles in regulating intestinal calcium absorption and in bone metabolism.
Calciferol is an alcohol C28H43OH usually prepared by irradiation of ergosterol and used as a dietary supplement in nutrition and medicinally in the control of rickets and related disorders.
Calciferol is a dietary supplement that is used to treat vitamin D deficiency.
Calciferol is also used with calcium to maintain bone strength.
Calciferol is a fat-soluble, crystalline, unsaturated alcohol, C28H43OH, occurring in milk, fish-liver oils, etc., produced by ultraviolet irradiation of ergosterol, and used as a dietary supplement, as in fortified milk.
Calciferol (vitamin D3) is used as a dietary supplement when the amount of vitamin D in the diet is not enough.
Calciferol, is a supplement that helps your body absorb calcium.
Calciferol belongs to the class of 'Vitamins', primarily used to treat low blood calcium levels.
Calciferol effectively treats various conditions in the body like Vitamin D deficiency, osteoporosis (weak and brittle bones), hypoparathyroidism (parathyroid glands make low levels of calcium in the body), latent tetany (a muscle disease with low blood calcium levels) and rickets or osteomalacia (softening or deforming of bones due to lack of calcium). Vitamin D deficiency occurs when your body has low Vitamin D levels and is caused due to inadequate nutrition, intestinal malabsorption or lack of sunlight exposure.
Calciferol contains 'Cholecalciferol' is a form of vitamin-D.
Calciferol (vitamin D3) supplement acts by promoting the absorption of calcium, phosphates and Vitamin A from different organs and helps in maintaining overall health.
Calciferol is a strong inhibitory effect against bladder tumor promotion by sodium saccharin and induces cell differentiation in leukemia cells.
Calciferol also been shown to be an inhibitor of DNA polymerase.
Calciferol is a form of Vitamin D used in the treatment of specific medical conditions such as refractory rickets, hypoparathyroidism, and familial hypophosphatemia, as well as osteoporosis and chronic kidney disease.
Specifications
Appearance White powder to crystal
Purity(HPLC) min. 98.0 area%
Melting point 111.0 to 116.0 °C
Specific rotation [a]20/D +100 to +109 deg(C=1.5, EtOH)
Properties (reference)
Melting Point 114 °C
Specific Rotation 105° (C=1.5,EtOH)
Solubility in water Insoluble
Solubility (soluble in) Alcohol,Chloroform,Ether
Used at one time as a name for ercalciol (ergocalciferol or vitamin D 2), made by the ultra‐violet irradiation of ergosterol.
Calciferol, a synthetic version of natural vitamin D, is used in the treatment and prevention of vitamin D deficiency and its consequent diseases, such as rickets, hypoparathyroidism and hypophosphatemia.
Calciferol is a fat-soluble vitamin that plays a role in bone health, several cellular processes, and the maintenance of calcium and phosphorus levels in the body.
Calciferol is one of the five forms of vitamin D - vitamin D3.
Calciferol is a secosteroid - a steroid molecule with one ring open.
Biocidal Uses
Calciferol is approved for use as a biocide in the EEA and/or Switzerland, for: controlling rodents.
1. Calciferol can maintain normal metabolism of calcium and phosphorus, promote the body's absorption of calcium and phosphorus.
3. Calciferol is a fat-soluble vitamin. There are a dozen compounds that are known to have the effect of vitamin D.
4. Calciferol medicines.
Calciferol mainly can promote intestinal absorption and deposition of calcium and phosphorus for the treatment of rickets and osteomalacia.
5. Calciferol is mainly used in food, health products and other related products.
Calciferol is an unhydroxylated form of vitamin D3.
Calciferol is used as an essential mediator of intestinal calcium absorption and bone calcium metabolism.
Calciferol is also used as a therapeutic vitamin. Further, it is used as a nutritional supplement and to fortify foods. In addition to this, it is used as pharmaceutical drug and used in the treatment of respiratory diseases involving chronic inflammation such as asthma.
Calciferol, also known as cholecalciferol, is a kind of vitamin D, which is formed by 7-dehydrocholesterol generated after dehydrogenation of cholesterol by ultraviolet irradiation.
The molecular formula of vitamin D3 is C27H44O, and it is a fat-soluble vitamin.
Calciferol is also regarded as a hormonal agent forerunner that acts upon calcium as well as phosphorus metabolic process.
Proven to be real active type of vitamin D in the body.
There go to least 10 known kinds of vitamin D, yet the most essential are vitamin D2 (ergocalciferol) and vitamin D3 (cholecalciferol).
Calciferol is known as the “sunshine vitamin” because most people can synthesize their own vitamin D from UV rays and cholesterol in the skin with moderate exposure to the sun.
Calciferol is mainly composed of 7-dehydrocholesterol in the skin, which becomes vitamin D3 when exposed to sunlight.
Calciferol is one of the five forms of vitamin D.
Calciferol is a secosteroid, a steroid molecule with one ring open.
Calciferol is a steroid hormone produced in the skin when exposed to ultraviolet light or obtained from dietary sources. The active form of Calciferol, 1,25-dihydroxycholecalciferol plays an important role in maintaining blood calcium and phosphorus levels and mineralization of bone. The activated form of Calciferol binds to vitamin D receptors and modulates gene expression.
Calciferol, also known as vitamin D3, is the most important form of vitamin D family, which mainly regulates calcium and phosphorus metabolism in the body.
IUPAC names
(1S,3Z)-3-[(2E)-2-[(1R,3aS,7aR)-7a-methyl-1-[(2R)-6-methylheptan-2-yl]-2,3,3a,5,6,7-hexahydro-1H-inden-4-ylidene]ethylidene]-4-methylidenecyclohexan-1-ol
(1S,3Z)-3-{2-[(1R,3aS,4E,7aR)-7a-methyl-1-[(2R)-6-methylheptan-2-yl]-octahydro-1H-inden-4-ylidene]ethylidene}-4-methylidenecyclohexan-1-ol
(3,beta., 5Z, 7E)-9,10-Secocholesta-5,7,10(19)-trien-3-ol
(3S,5Z,7E)-9,10-secocholesta-5,7,10-trien-3-ol
(3β,5Z,7E)-9,10-secocholesta- 5,7,10(19)-trien-3-ol
(3β,5Z,7E)-9,10-secocholesta-5,7,10(19)-trien-3-ol
(5Z,7E)-9,10-Secocholesta-5,7,10(19)-triene-1α,3β-diol
9,10-SECOCHOLESTA-5,7,10(19)-TRIEN-3-OL,(3.BETA.,5Z,7E)-
9,10-secocholesta-5,7,10-trien-3-ol
cholecalciferol
COLECALCIFEROL
Colecalciferol
colecalciferol
colecalciferol; Vitamin D3
Cyclohexanol, 3-[(2E)-2-[(1R,3aS,7aR)-1-[(1R)-1,5-dimethylhexyl]octahydro-7a-methyl-4H-inden-4-ylidene]ethylidene]-4-methylene-, (1S,3Z)-
Vitamin D3
Vitamin D3
SYNONYMS:
Vitamin D3 solution
Vitamin D3-d3 Cholecalciferol (6,19,19-d3)
Cholecalciferol d6
Vitamin D3-d6
10-Secocholesta-5,7,10(19)-trien-
(5Z,7E,3S)-9,10-Secocholesta-5,7,10(19)-trien-3-ol
3Z-[2E-[(1R,3aS,7aR)-1S-[1R,5-dimethylhexyl]octahydro-7a-methyl-4H-inden-4-ylidene]ethylidene]-4-methylene-cyclohexanol
(+)-VITAMIN D/3, CRYSTALLINE, 99+%
CHOLECALCIFEROL, PH EUR
CHOLECALCIFEROL CRYSTALLINE
CHOLECALCIFEROL, USP
VITAMIN D3 99+%
VitaminD3(Cholecalciferol40000Iu)
VitaminD3MedicalGrade
VitaminD2MedicalGrade
VitaminD3CrystalPowder(40,000,000Iu)
Cholecalciferol/VitamineD3
VitaminD3U.S.P.
VitaminD/VitaminD3
cholecalciferol,d3
d3-vicotrat
D3-Vigantol
Delsterol
Deparal
duphafrald31000
Ebivit
Micro-dee
neodohyfrald3
Provitina
rampage
Ricketon
Trivitan
VidDe-3-hydrosol
5,7,10(19)-CHOLESTATRIEN-3BETA-OL-9,10-SECO
Cholecalciferol, USP Grade 9,10-Secocholesta-5,7,19(19)-trien-3-OL-(3B,5Z,7E)-choleciferol, USP Grade
vitamin D3 ~40000 U/mg
CHOLECALCIFEROL, PHARMA
Vitamin D3
