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EC / List no.: 205-278-9
CAS no.: 137-08-6
Calcium Pantothenate is the calcium salt of the water-soluble vitamin B5, ubiquitously found in plants and animal tissues with antioxidant property.
Pentothenate is a component of coenzyme A (CoA) and a part of the vitamin B2 complex.
Vitamin B5 is a growth factor and is essential for various metabolic functions, including the metabolism of carbohydrates, proteins, and fatty acids.
This vitamin is also involved in the synthesis of cholesterol, lipids, neurotransmitters, steroid hormones, and hemoglobin.
Calcium pantothenate is a polymer.
Nutritional supplement
Calcium pantothenate as components of coenzyme A regulates the metabolism of protein, saccharide, and fat, and prevents diseases, which is indispensable substance for growth and development of domesticated creatures and fishes, for fatty synthesis and decomposition.
The lack of Calcium Pantothenate would result in the slow growth of poultry and the malfunction of reproduction mechanisms.
Therefore, Calcium Pantothenate as a growth factor is used in feed additives.
In addition, Calcium Pantothenate is also as food enrichment widely used in food industries, sun as breakfast cereals, beverages, dietetic, and baby foods.
Calcium Pantothenate has the function of making antibodies and Calcium Pantothenate plays an important role in the fight against pressure to maintain hair, skin and blood health, and also contributes to improving the deficiency and neuritis.
Thus, it has broad medical value and has been applied in pharmaceutical industries that single-dose is used for pantothenic acid deficiency, complex of vitamins B and multivitamins are used for vitamin supplement, and other compounds with different components are widely used for gastrointestinal diseases, respiratory diseases, skin diseases, mental inactivity, neurasthenia, and so on.
Production method Take isobutyraldehyde as raw material, carry out hydroxymethylation, addition reaction, hydrolysis, acidification, lactonization and acylation to derive the final product.
Formaldehyde and anhydrous potassium carbonate are sent into the reaction pot.
At 14-20 °C, it is added dropwise of isobutyraldehyde.
After the completion of the addition, incubate for stirring reaction for 3h, and then stand at 14-18 °C for 0.5 h to obtain the upper oil-2, 2-dimethyl-3-hydroxypropionaldehyde.
2, 2-dimethyl-3-hydroxypropanal is dissolved in 4 times the water while the sodium cyanide is dissolved in 6 times the water and calcium chloride dissolved in 2 times the water.
The above solutions are successively added into the reaction pot.
50% sulfuric acid solution was added under stirring at 60-65 ° C for 6h, then being heated to 80-85 °C for 3h and subject to vacuum concentration to being thick.
95% ethanol was added to precipitate the inorganic salt and filtrate.
After the recovery of ethanol through distillation under reduced pressure, collect the fractions of 130-145C (1.33-2.39 Kpa), namely ?-butyrolactone.
Then, β-aminopropionic acid, 5/6 methanol and lime were successively added to the reactor.
Raise the temperature to 40 °C, and the reaction was stirred for 2 hours.
The reaction mixture was allowed to stand for while before the supernatant was filtered by filtration.
The solid residue in the pot was washed with 1/6 methanol and then filtered.
The filtrate is placed in another reaction pot, being added of γ-butyrolactone for stirring and dissolving in room temperature for 40 h reaction to generate calcium pantothenate.
Stirring with water and cooling to-5-0 °C, and add seed crystal for stirring of 24 hours, filter to obtain the dextro calcium pantothenate.
2/3 the amount of calcium pantothenate and calcium p-pantothenate are thrown into the reaction pot, add methanol and water, heat to 40 °C for stirring dissolving and filter upon being hot.
The filtrate is cooled to 15 °C, added of a small amount of calcium L-pantothenate and crystal for 2h.
When the specific rotation is up to +6 °-+8 °, separate the crystal, and wash with a small amount of methanol to obtain the L-calcium p-pantothenate (still used for resolution).
The remaining 1/3 racemic calcium pantothenate was dissolved in a filtrate of 35-40 ° C, filtered and cooled to 15 ° C.
A small amount of calcium p-pantothenate was added and the crystals were incubated for 2 hours.
Crystals were separated when the specific rotation was-0.8 °--0.6 °, washed with a small amount of methanol and dried in vacuo to give calcium dextrate.
Calcium Pantothenate is derived through the heating and condensation between calcium β-alanine and α-hydroxy β, β-dimethyl-γ-butyl ester.
Uses
1. Calcium Pantothenate can be applied to biochemical studies; as the nutrient composition of tissue culture medium. Calcium Pantothenate is clinically used for the treatment of vitamin B deficiency, peripheral neuritis and postoperative colic.
2. Calcium Pantothenate can be used as food fortifier, also used as infant food with the usage amount of 15~28 mg/kg; it is 2~4mg/kg in the drink.
3. This product is a vitamin drugs, being an integral part of coenzyme A.
In the mixture of calcium pantothenate, only the right-hand body has vitamin activity, participating into the in vivo metabolism of protein, fat and carbohydrate.
Calcium Pantothenate can be used for the treatment of vitamin B deficiency and peripheral neuritis, and postoperative colic.
Its combined treatment with vitamin C can be used for the treatment of disseminated lupus erythematosus.
The lack of calcium pantothenate in human body has the following symptoms:
(1) growth arrest, weight loss and sudden death.
(2) Skin and hair disorders.
(3) Neurological disorders.
(4) Digestive disorders, liver dysfunction.
(5) Affect the antibody formation.
(6) Kidney dysfunction.
Every day the body demands 5 mg of calcium pantothenate (calculated based on pantothenic acid).
Calcium pantothenate, as a nutritional supplement, can be used for the food processing.
In addition to special nutritional food, the usage amount should be below 1% (calculated on calcium) (Japan).
Upon the strengthening of the milk powder, the usage amount should be 10 mg/100g.
Addition of 0.02% into the Shochu and whiskey can further enhance the flavor.
Addition of 0.02% into the honey can prevent the winter crystallization.
Calcium Pantothenate can be used for buffering the bitterness of caffeine and saccharin.
4. Calcium Pantothenate can be used as feed additives, food additives, being in line with Pharmacopoeia USP28/BP2003
5. Calcium Pantothenate can be used as nutritional supplements, being able to enhance the flavor of shochu whiskey to prevent the crystallization of honey in winter.
6. Calcium Pantothenate is the precursor product for the biosynthesis of coenzyme A.
Because of the easy-deliquescence of pantothenic acid and other unstable properties, it is used of calcium salt as the substitute.
Chemical properties
Calcium Pantothenate appears as white crystalline (methanol), being hygroscopic.
Calcium Pantothenate is stable to the light and air with its aqueous solution being weakly alkaline.
Its Mp is 195-196 °C (decomposition); Specific rotation [α] 26D + 28.2 ° (5%, water).
Calcium Pantothenate is soluble in water and glycerol, being slightly soluble in acetone and ethanol.
Uses:
D-(+)-Pantothenic acid calcium salt is a member of the B complex vitamins, essential vitamin for the biosynthesis of coenzyme A in mammalian cells.
Occurs ubiquitously in all animal and plant tissue.
The richest common source is liver, but jelly of the queen bee contains 6 times as much as liver.
Rice bran and molasses are other good sources.
calcium pantothenate is used as an emollient and to enrich creams and lotions in hair care preparations.
This is the calcium salt of pantothenic acid found in liver, rice, bran, and molasses.
Calcium Pantothenate is also found in large amounts in royal jelly.
Calcium Pantothenate is a nutrient and dietary supplement which is the calcium chloride double salt of .
Calcium Pantothenate is a white powder of bitter taste and has a solubility of 1 g in 3 ml of water.
Calcium Pantothenate is used in special dietary foods.
Manufacturing Process
A mixture of 288 g (4 mols) of isobutyraldehyde, 288 g of methanol was cooled to 10°C and 170 g (2 mols) of 36.6% formalin containing 8.5 g (3% based on isobutyraldehyde) of sodium hydroxide was added dropwise over a 55 minute period to produce alpha,alpha-dimethyl-beta-hydroxy-propionaldehyde.
The mixture was stirred for an additional 2 hours at 10-15°C and then contacted with acetic acid to neutralize the catalyst.
The excess isobutyraldehyde and methanol were stripped off at a kettle temperature of 50°C at 25 mm.
To the residual α,α-dimethyl-beta-hydroxypropionaldehyde a mixture of 260 ml of methanol and 2 g (0.75%) sodium cyanide was added and the solution cooled to 10°C before adding 59.4 g (2.2 mols) of hydrogen cyanide dropwise over a 35 minute period to produce α,γ-dihydroxy-β,β- dimethylbutyronitrile.
The mixture was stirred at 10°C for one hour period and then contacted with acetic acid to neutralize the catalyst before stripping off the excess methanol to a kettle temperature of 45°C at 18 mm.
The crude cyanohydrin was then hydrolysed by heating with 4 mols of concentrated hydrochloric acid at 80°C for 2 hours, then diluting with an equal volume of water and heating at 100°C for an additional 8 hours.
The aqueous mixture was extracted continuously with ethylene dichloride.
The solvent was removed, and pantolactone (B. P. 131°C/19 mm, M.P. 61-77°C, 96.5% purity by saponification) was obtained by distillation in 71.5% yield based on formaldehyde and 55% efficiency based on isobutyraldehyde.
26 grams of racemic pantolactone (0.2 mol) and 1.1 grams of sodium methoxide (0.02 mol) contained in 30 ml of methanol, were added to 78.8 grams of 1-brucine (0.2 mol) contained in 156 ml of methanol.
The resulting mixture was refluxed for 1.5 hours and allowed to stand at room temperature overnight.
After centrifuging, washing with methanol and drying, 65.4 grams of D-(-)-pantolactone 1-brucine (62% of theory based upon all of the racemic pantolactone) melting at 203° to 206°C were obtained.
Upon chilling the mother liquor, 13.46 grams of additional complex melting at 175° to 177°C were obtained.
D-(-)-Pantolactone was obtained from the complex in the following manner.
The 65.4 grams of complex obtained above were treated with 65 ml of chloroform and 5.35 grams of sodium hydroxide contained in 35 ml of water for one hour at room temperature.
The aqueous layer was extracted 6 times with 20 ml portions of chloroform in order to remove the brucine.
The sodium pantoate contained in the aqueous layer was relactonized by treatment with 11 ml of concentrated hydrochloric acid.
Extraction of the crude D-(-)- pantolactone yielded 15.29 grams.
This material was then recrystallized from 7 ml of methyl isobutyl ketone and 7 ml hexane thereby yielding 9.77 grams of D-(-)-pantolactone (37% of theory).
The αD25 was -44.8°.
Into a vessel equipped with an agitator and reflux condenser are placed approximately 52 parts by weight of α-hydroxy-β,β-di-methyl-γ-butyrolactone, approximately 36 parts by weight of β-alanine, about 40 parts by weight of diethylamine and about 100 parts by weight of anhydrous methanol.
The mixture is stirred and refluxed for about 12 hours until the reaction is complete as evidenced by the dissolution of the β-alanine.
To this resulting mass is gradually added 8 parts by weight of calcium metal nodules or pellets and refluxing continued until the metal is dissolved.
The diethylamine and alcohol are distilled off until the residue becomes viscous.
The viscous residue is dried under vacuum at 100°C. The solid residue recovered, as biologically assayed, indicated a 91% yield of calcium pantothenate.
General Description
The first suggestion for the existance of vitamin B5 came from Carter et al. in 1930, although it was never characterized or isolated.
This vitamin is synthesized by most green plants and microorganisms.
Excellent sources of the vitamin are liver, egg yolk, whole grains, and fortified ready-to-eat cereals.
However, as the original name implies, many foods contain sufficient pantothenic acid to supply dietary needs.
Chemically, pantothenic acid is considered to be aβ-alanine derivative of the asymmetric pantoic acid and thus shows asymmetry.
Only the naturally occurring D(+)- stereoisomer (with R configuration) is biologically active and the L(-)-stereoisomer (with S configuration) is inactive.
When its carboxylate functional group is attached through an amide linkage with β-mercaptoethylamine, it is known as pantetheine (also spelled pantotheine).
The biologically active form of pantothenic acid, CoA, is formed when the terminal alcoholic function of pantetheine is attached to ADP 3'-phosphate.
Pantothenic acid plays a part in the processes that release energy from food, and contributes to normal mental performance.
Calcium Pantothenate also contributes to the normal synthesis of our natural steroid hormones and nerve chemicals called neurotransmitters.
Like many of the B vitamins it also contributes to the reduction of tiredness and fatigue.
Calcium pantothenate is a form of pantothenic acid, or vitamin B5.
Found in plants and animal tissues as well as cereal grains, eggs legumes, and milk.
Most known for protecting cells against peroxidative damage by increasing the level of glutathione--an important compound aiding in the oxidation-reduction of cells.
Calcium pantothenate and the benefits it provides is essentially a study of vitamin B5.
Of the eight B-vitamins, vitamin B5 is often overlooked.
Calcium Pantothenate plays an important role in helping enzymes work effectively, it’s water-soluble, and an essential nutrient that synthesizes and metabolizes fats, carbs, and proteins.
These functions give vitamin B5 far-reaching effects on how the body functions.
Calcium pantothenate is alternately known as pantothenic acid or vitamin B5 or panthenol, which is a composition of 8% calcium and 92% pantothenic acid.
Calcium Pantothenate is water-soluble but gets destroyed easily by heat of freezing, cooking water, and alkalis like vinegar and baking soda.
Calcium pantothenate is vital in major body processes.
This vitamin is necessary for the production of certain hormones such as steroids, adrenal glands, and proper functioning of the nervous system
Calcium Pantothenate can be found in many cells of the body and stays in the cell membranes.
Within the cell membranes, calcium pantothenate aids in the metabolism of carbohydrates, fats and proteins, and other acetylation reactions, for the release of energy.
These processes include the breakdown of fats into energy and the manufacture of cholesterol.
Calcium pantothenate has a part in synthesizing hemoglobin, steroid hormones, lipids, and neurotransmitters.
Other benefits of calcium pantothenate include protecting the body against stress, cellular damage due to free radicals, allergies, and reduce side effects of some drugs.
In fact, it has been known to relieve or prevent depression due to this ability.
Additionally, this vitamin helps the body absorb and utilize other vitamins more efficiently.
Calcium Pantothenate helps in managing migraines, chronic fatigue syndrome, and quitting smoking and drinking alcoholic beverages.
Vitamin B5 is one of the most crucial B vitamins for humans, Calcium Pantothenate is also known as Calcium pantothenate or pantothenic acid. It's necessary for making blood cells, and Calcium Pantothenate helps convert the food into energy.
Vitamin B5 is used in the fortification of foods and supplements.
White powder
Starting Material: D-Pantolactone, B-Alanine
Processing Method: Reaction
Soluble in water
Application
Calcium pantothenate has been used:
• as a component of vitamin solution for synthetic media
• as a component of vitamin mix for the ICS medium mix
• as a component of a chemically defined diet for metal depletion studies in Drosophila
• as a supplement to study coenzyme A metabolism in mouse models of non-alcoholic steatohepatitis
Precursor in the biosynthesis of coenzyme A.
Biochem/physiol Actions
The calcium salts of panthenol are commonly used for pharmaceutical preparations.
Pantothenate is a component of coenzyme A and is useful in its synthesis.
Pantothenic acid is also involved in the synthesis of heme, cholesterol and fatty acids.
Since vitamin B5 is found in all foods, its deficiency is not commonly observed.
General description
Vitamin B5 or pantothenic acid is a viscous oil that is soluble in ethanol and water.
Calcium pantothenate is produced by plants and microorganisms.
Calcium pantothenate is the naturally occurring form of pantothenic acid and is biologically active.
Calcium pantothenate is a water-soluble member of the B-vitamin family that is converted into 4’-phosphopantetheine, which is then converted to co-enzyme A (CoA) via adenosine triphosphate.
Pantothenic acid regulates epidermal barrier function and keratinocytes differentiation via CoA metabolism.
Pantothenic acid is incorporated into co-enzyme A and protects cells against peroxidative damage by increasing the level of glutathione.
A recent feasibility study has also shown that daily oral supplementation of a nutritional agent containing pantothenic acid for 8 weeks was feasible and safe.
Calcium Pantothenate was discovered the different pharmacological implementation of pantothenic acid, such as treatment of acne, obesity. Existed some reports, mentioned efficacy using pantothenic acid in systemic lupus erythematosus.
Significant reduction in morning stiffness, degree of disability, and severity of pain was reported for persons taking pantothenic acid in case of osteoarthritis and rheumatoid arthritis.
Calcium pantothenate may increase the effects of a group of drugs called cholinesterase inhibitors, which are used to treat Alzheimer's disease.
Calcium pantothenate > for food fortification
BTC offers a wide range of different Vitamins.
To secure an adequate vitamin B5-level in humans, it is often added to different types of food products.
Our technical expertise might help you develop your end-product
Physiological importance
Calcium pantothenate is an essential component of coenzyme A as well as certain peptide coenzymes, in the form of which it is involved in various key reactions of the amino acid, fat and carbohydrate metabolisms.
Pantothenic acid plays an important role for the growth and normal function of body tissue.
Calcium Pantothenate protects the mucous membranes from infection and optimizes metabolic processes of the skin and epithelial tissue.
Calcium Pantothenate is also involved in regenerative processes of the skin such as wound healing and epithelisation as well as in stimulating hair growth and pigmentation.
IUPAC NAMES:
(R)-N-(2,4-Dihydroxy-3,3-dimethyl-1-oxobutyl)-beta-alanine calcium salt
calcium 3-[[(2R)-2,4-dihydroxy-3,3-dimethylbutanoyl]amino]propanoate
calcium bis(3-[(2R)-2,4-dihydroxy-3,3-dimethylbutanamido]propanoate)
calcium bis(3-{[(2R)-2,4-dihydroxy-3,3-dimethylbutanoyl]amino}propanoate)
Calcium pantothenate
Calcium pantothenate , D-form
calcium pantothenate , D-form
N-(2,4-dihydroxy-3,3-dimethyl-1-oxobutyl)-b-alanine calcium salt
N-(2,4-dihydroxy-3,3-dimethylbutanoyl)-beta-alanine
SYNONYMS:
calcium pantothenate
137-08-6
D-Calcium pantothenate
Calpanate
Calcium D-pantothenate
Pantothenate calcium
Pantholin
Pancal
UNII-568ET80C3D
Cris Pan
Calcium panthothenate
Ca-HOPA
D-Pantothenic Acid Hemicalcium
Dextro calcium pantothenate
Vitamin B5, calcium salt
568ET80C3D
Calcium pantothenate (2:1)
Pantothenic acid, calcium salt
D-Pantothenic acid hemicalcium salt
Calcium D-Panthotenate
pantothenic acid calcium
Calcium (R)-3-(2,4-dihydroxy-3,3-dimethylbutanamido)propanoate
Calpan
Pantothenic acid calcium salt
D-Calcium pantothenate calcium chloride double salt
Calcii pantothenas
D-Pantothenic Acid Calcium Salt
Pantotenato calcico
N-(2,4-Dihydroxy-3,3-dimethylbutyryl)-beta-alanine calcium
Pantothenate de calcium
Bis(pantothenato)calcium
NCGC00183031-01
Calcium pantothenate (VAN)
Calcium, bis(pantothenato)-
Calcium pantothenate , D-form
CCRIS 1338
Calcii pantothenas [INN-Latin]
Calcium D-pantothenate (1:2)
Pantotenato calcico [INN-Spanish]
EINECS 205-278-9
Calcium pantothenate [USP:INN:JAN]
Calpan (TN)
NSC 36292
Pantothenate de calcium [INN-French]
Vitamin B5 calcium salt
Pantothenic acid, calcium salt (2:1), D-
Pantothenic acid, calcium salt, D-, compd. with calcium chloride
D-Pantothenic Acid Calcium
Pantothenic acid, calcium salt (2:1), (+)-
DSSTox_CID_20438
DSSTox_RID_79493
DSSTox_GSID_40438
SCHEMBL34427
CHEMBL1901349
DTXSID8040438
CHEBI:31345
Tox21_113437
AKOS024258157
Calcium pantothenate (JP17/USP/INN)
beta-Alanine, N-(2,4-dihydroxy-3,3-dimethyl-1-oxobutyl)-, calcium salt (2:1), (R)-
Calcium D(+)-N-(alpha,gamma-dihydroxy-beta,beta-dimethylbutyryl)-beta-alaninate
Calcium N-(2,4-dihydroxy-3,3-dimethyl-1-oxobutyl)-beta-alanine (1:2), (R)-
AS-13049
CAS-137-08-6
P0012
D01082
D70806
A807185
Pantothenic acid calcium 10 microg/mL in Acetonitrile
Q27261387
UNII-2KC899R47Q component FAPWYRCQGJNNSJ-UBKPKTQASA-L
Calcium N-(2,4-dihydroxy-3,3-dimethyl-1-oxobutyl)-beta-alanine
beta-Alanine, N-(2,4-dihydroxy-3,3-dimethyl-1-oxobutyl)-, calcium salt
calcium 3-[[(2R)-2,4-dihydroxy-3,3-dimethyl-butanoyl]amino]propanoate
beta-Alanine, N-((2R)-2,4-dihydroxy-3,3-dimethyl-1-oxobutyl)-, calcium salt (2:1)
beta-Alanine, N-(2,4dihydroxy-3,3-dimethyl-1-oxobutyl)-, calcium salt (2:1), (theta)-
(+)-PANTOTHENIC ACID CALCIUM SALT
PANTOTHENIC ACID CALCIUM SALT
(R)-(+)-N-(2,4-DIHYDROXY-3,3-DIMETHYL-1-OXOBUTYL)-BETA-ALANINE HEMICALCIUM SALT
(theta)-
beta-alanine,n-(2,4-dihydroxy-3,3-dimethyl-1-oxobutyl)-,calciumsalt(2:1),
N-(2,4-dihydroxy-3,3-dimethyl-1-oxobutyl)-,calciumsalt(2:1),(R)-.beta.-Alanine
N-(2,4-Dihydroxy-3,3-dimethyl-1-oxobutyl)-alaninecalciumsalt
n-(2,4-dihydroxy-3,3-dimethylbutyryl)-beta-alaninecalcium
pancal
panthoject
Pantholin
.beta.-Alanine, N-(2R)-2,4-dihydroxy-3,3-dimethyl-1-oxobutyl-, calcium salt (2:1)
D-CALCIUM PANTOTHENATE USP
CALCIUMPANTOTHENATE,FCC
CALCIUMPANTOTHENATE,POWDER,USP
CALCIUMPANTOTHENATE,ULTRAPURE
VITAMIN B5
VITAMIN B3/B5
Calcium D-(+)-N-(α,γ-dihydroxy-β,β-dimethylbutyryl)-β-alaninate
Calcium, bis(pantothenato)- (7CI)
Calpan
N-(2,4-Dihydroxy-3,3-dimethylbutyryl)-b-alanine calcium
NSC 36292
Pantothenic acid hemicalcium salt
Pantothenic acid, calcium salt (2:1), D- (8CI)
Vitamin B5 calcium salt
β-Alanine, N-(2,4-dihydroxy-3,3-dimethyl-1-oxobutyl)-, calcium salt (2:1), (R)-
β-Alanine, N-[(2R)-2,4-dihydroxy-3,3-dimethyl-1-oxobutyl]-, calcium salt (2:1)
Calcium-D-pantothenat
CALCIUMPANTOTHENAT
(R)-.beta.-Alanine
N-(2,4-dihydroxy-3,3-dimethyl-1-oxobutyl)-, calcium salt
(R)-(+)-N-(2,4-Dihydroxy-3,3-dimethyl-1-oxobutyl)-b-alanine hemicalcium salt
CALCIUM PANTOTHENATE pure
D-Pantothenic acid hemicalcium salt, Calcium D-pantothenate, VitaminB5, (R)-(+)-N-(2,4-Dihydroxy-3,3-dimethyl-1-oxobutyl)-β-alanine hemicalcium salt
CalciuM 3-(2,4-dihydroxy-3,3-diMethylbutanaMido)propanoate
CalciuM (R)-3-(2,4-dihydroxy-3,3-diMethylbutanaMido)propanoate
CalciuM D-pantothenatealanine heMicalciuM salt
d-calcium pantothanate
Calcium D-Panthotenate
Pantothenic Acid/pantothenate/vitamin B5
D-Calcium Panthotenate(Vitamin B5)
CALCIUM (+)-PANTOTHENATE
CALCIUM PANTOTHENATE
CALCIUM D-(+)-PANTOTHENATE
CALCIUM D-PANTOTHENATE
CALCIUM DEXTRO-ANTOTHENATE
D-CALCIUM PANTATHENATE
D-CALCIUM PANTHOTENA
D-(+)-CALCIUM PANTOTHENATE
D-CALCIUM PANTOTHENATE
D-VITAMIN B CALCIUM SALT
D-PANTOTHENIC ACID, CALCIUM
D-PANTOTHENIC ACID CALCIUM SALT
D(+)-PANTOTHENIC ACID HEMICALCIUM SALT
-Cypermethrin 1-Epimeric Mixture
Calcium pantothenate (Vitamin B5
D-PANTOTHENIC ACID CALCIUM SALT) in stock GMP Factory
