CAPRYLOYL GLYCINE

Capryloyl Glycine is an amino-acid-derived lipoamino acid obtained by acylating glycine with caprylic (octanoic) acid, and Capryloyl Glycine is widely used in cosmetic and personal care formulations for sebum-balancing, deodorant support, and skin-clarifying concepts.
Capryloyl Glycine is valued for helping reduce the appearance of oily shine, supporting skin comfort, and contributing to an environment less favorable for odor-causing microorganisms, while Capryloyl Glycine also supports gentle, skin-friendly positioning.
Capryloyl Glycine is commonly used in acne-prone skin care, deodorants, scalp care, and hygiene products, and Capryloyl Glycine performance depends on pH, solubilization, and the overall preservation and surfactant system.

CAS Number: 14246-53-8 (commonly associated; supplier grade dependent)
EC Number: 238-122-4 (commonly associated; supplier grade dependent)
Molecular Formula: C10H19NO3
Molecular Weight: 201.26 g/mol

Synonyms: Capryloyl Glycine, N-Capryloyl Glycine, N-Octanoyl Glycine, Octanoyl Glycine, Caprylic Acid Glycine Amide (common naming), Capryloylglycine, Lipoamino Acid Capryloyl Glycine, Sebum-Regulating Capryloyl Glycine, Deodorant Active Capryloyl Glycine, Skin Clarifying Capryloyl Glycine, Capryloyl Glycine Cosmetic Ingredient, Capryloyl Glycine Powder, Capryloyl Glycine, CAPRYLOYL GLYCINE, Capryloyl glycine, Capryloylglycine, N-Capryloyl Glycine, N-Capryloylglycine, N-Octanoyl Glycine, N-Octanoylglycine, Octanoyl Glycine, Octanoylglycine, Glycine, N-octanoyl-, 2-(Octanoylamino)acetic Acid, 2-(octanoylamino)acetic acid, Octanoylaminoacetic Acid, Octanoylamino acetic acid (spacing variant), Caprylic Acid Glycine Amide (common descriptive), Caprylic Acid Glycine Derivative, Caprylic Glycine (common short name), Glycine Caprylate (common misname), Glycine Capryloyl (common variant), Capryloylglycine (INCI), Capryloyl Glycine (INCI), Capryloyl Glycine (cosmetic ingredient), Capryloyl Glycine (skin conditioning agent), Capryloyl Glycine (sebum regulator) (use context), Capryloyl Glycine (anti-acne active) (use context), Capryloyl Glycine (anti-microbial) (use context), Capryloyl Glycine (deodorant active) (use context), Capryloyl Glycine (odor control) (use context), Capryloyl Glycine sebum control agent (use context), Capryloyl Glycine deodorizing agent (use context), Capryloyl Glycine antimicrobial active (use context), Capryloyl Glycine preservative booster (use context), Capryloyl Glycine formulation active, Capryloyl Glycine personal care grade, Capryloyl Glycine cosmetic grade, Capryloyl Glycine high purity, Capryloyl Glycine powder, Capryloyl Glycine crystals, Capryloyl Glycine granules, Capryloyl Glycine solution (common supply form), Capryloyl Glycine in propylene glycol (formulation), Capryloyl Glycine in glycerin (formulation), Capryloyl Glycine blend (formulation), Capryloyl Glycine seboregulating lipoamino acid, Lipoamino acid (Capryloyl Glycine), Capryloyl Glycine lipoamino acid, Octanoyl Glycine lipoamino acid, Capryloyl Glycine amino acid derivative, N-Acyl Glycine (Capryloyl), N-Acylglycine (Capryloyl), Capryloyl Glycine (C10H19NO3) (composition wording), C10H19NO3, Capryloyl Glycine (CAS 14246-53-8) (common listing), CAS 14246-53-8, Capryloyl Glycine (octanoylglycine), Octanoylglycine (Capryloyl Glycine)

APPLICATIONS

Capryloyl Glycine is used in oily-skin moisturizers to help reduce greasy feel and support a more balanced skin appearance.
Capryloyl Glycine is incorporated into mattifying creams to help control shine in the T-zone area.
Capryloyl Glycine is used in lightweight gels to support sebum-control concepts without heavy occlusion.

Capryloyl Glycine is used in acne-prone skincare to support clearer-looking skin and reduce the look of blemish-prone oiliness.
Capryloyl Glycine is incorporated into anti-blemish serums to complement exfoliating acids and gentle antimicrobials.
Capryloyl Glycine is used in spot treatments to support skin-purifying and calming routines in compatible designs.

Capryloyl Glycine is used in facial cleansers to support skin purification and reduce oily residue after rinsing.
Capryloyl Glycine is incorporated into sulfate-free cleansing systems to support mildness and post-wash comfort.
Capryloyl Glycine is used in foaming cleansers to help maintain a fresh skin feel during daily use.

Capryloyl Glycine is used in toners to support sebum-balancing and skin-clarifying product positioning.
Capryloyl Glycine is incorporated into leave-on essences to help improve skin comfort in oily and combination skin routines.
Capryloyl Glycine is used in facial mists to provide light active delivery and refresh oily skin during the day.

Capryloyl Glycine is used in deodorants to help reduce malodor by supporting control of odor-causing microorganisms.
Capryloyl Glycine is incorporated into roll-on deodorants to improve freshness perception and support longer-lasting odor control.
Capryloyl Glycine is used in deodorant creams to support gentle deodorancy with skin-friendly positioning.

Capryloyl Glycine is used in underarm care products designed for sensitive skin when formulation pH and compatibility are optimized.
Capryloyl Glycine is incorporated into fragrance-free deodorants to support odor control without heavy perfume masking.
Capryloyl Glycine is used in post-shave underarm products to support comfort while maintaining deodorant performance.

Capryloyl Glycine is used in scalp care shampoos to support oily scalp management and reduce scalp discomfort associated with excess sebum.
Capryloyl Glycine is incorporated into anti-dandruff support shampoos to complement scalp-balancing strategies.
Capryloyl Glycine is used in scalp tonics to support fresher scalp feel and improved comfort between washes.

Capryloyl Glycine is used in facial masks to support skin purification and reduce the appearance of oily shine.
Capryloyl Glycine is incorporated into clay masks to support sebum-absorbing and clarifying performance.
Capryloyl Glycine is used in wash-off masks to support a cleaner, smoother skin feel after rinse-off.

Capryloyl Glycine is used in body washes and intimate hygiene products to support freshness and odor control in compatible systems.
Capryloyl Glycine is incorporated into feminine hygiene washes where mildness and pH control are carefully designed.
Capryloyl Glycine is used in hygiene wipes to support freshness and reduce malodor risk after opening.

Capryloyl Glycine is used in men’s grooming products to support oil control and improved skin feel.
Capryloyl Glycine is incorporated into beard and face cleansers to reduce greasy residue and improve comfort.
Capryloyl Glycine is used in aftershaves and post-shave balms to support fresh skin sensation in compatible formulations.

Capryloyl Glycine is used in foot care creams to support deodorant performance and comfort in high-odor areas.
Capryloyl Glycine is incorporated into foot sprays to support freshness and reduce unpleasant odor development.
Capryloyl Glycine is used in shoe-deodorizing products where antimicrobial support is desired in compatible designs.

Capryloyl Glycine is used as a supportive ingredient in preservation strategies to help reduce microbial load in certain formulations.
Capryloyl Glycine is incorporated into “preservative booster” concepts to improve overall robustness when paired with suitable preservatives.
Capryloyl Glycine is valued because Capryloyl Glycine supports sebum balance, freshness, and deodorant performance while fitting modern gentle-skin formulation approaches.

Capryloyl Glycine is used in cosmetic formulations as a sebum-balancing skin-conditioning ingredient.
Capryloyl Glycine is used to support clearer-looking skin in oily and blemish-prone routines.
Capryloyl Glycine helps improve skin feel by reducing greasy shine perception.

Capryloyl Glycine is used in facial cleansers designed for oily skin types.
Capryloyl Glycine supports gentle cleansing concepts while targeting excess sebum perception.
Capryloyl Glycine helps maintain a fresh after-feel after rinsing.

Capryloyl Glycine is used in foaming face washes to support anti-blemish positioning.
Capryloyl Glycine helps reduce the appearance of oiliness that can accompany breakouts.
Capryloyl Glycine supports clean, comfortable skin feel in daily cleansing.

Capryloyl Glycine is used in micellar waters and cleansing waters for oily skin concepts.
Capryloyl Glycine supports mild cleansing while contributing to purifying positioning.
Capryloyl Glycine helps improve sensory freshness without strong astringency.

Capryloyl Glycine is used in facial toners aimed at reducing shine and improving skin balance.
Capryloyl Glycine supports a refined skin feel in toner steps.
Capryloyl Glycine helps maintain comfortable skin feel without over-drying when properly formulated.

Capryloyl Glycine is used in acne-prone skin care routines as a complementary active alongside acids.
Capryloyl Glycine supports blemish care claims by contributing to a less oily skin environment.
Capryloyl Glycine helps improve tolerance and comfort when paired with exfoliating actives.

Capryloyl Glycine is used in lightweight facial gels for oily and combination skin types.
Capryloyl Glycine supports non-greasy texture design and quick absorption perception.
Capryloyl Glycine helps keep skin feeling fresh throughout the day.

Capryloyl Glycine is used in mattifying moisturizers to help reduce shiny appearance.
Capryloyl Glycine supports matte-finish formulations with balanced skin feel.
Capryloyl Glycine helps improve the cosmetic appearance of pores by reducing oil-related shine.

Capryloyl Glycine is used in oil-control serums that target excess sebum appearance.
Capryloyl Glycine supports smoother-looking skin texture in leave-on products.
Capryloyl Glycine helps maintain a balanced skin feel with regular use.

Capryloyl Glycine is used in pore-minimizing cosmetic concepts where oil control is part of the story.
Capryloyl Glycine supports improved visual uniformity by reducing surface oiliness.
Capryloyl Glycine helps enhance the look of makeup wear on oily skin.

Capryloyl Glycine is used in primer products for oily skin to support matte effect.
Capryloyl Glycine helps improve skin feel and reduces greasy slip before makeup.
Capryloyl Glycine supports longer-lasting makeup appearance by controlling shine perception.

Capryloyl Glycine is used in foundations and BB creams designed for oily skin.
Capryloyl Glycine supports shine control and improved wear performance in color cosmetics.
Capryloyl Glycine helps reduce oil breakthrough and patchiness perception during the day.

Capryloyl Glycine is used in setting sprays and finishing mists to support long-wear makeup on oily skin.
Capryloyl Glycine supports balanced skin feel and improved finish.
Capryloyl Glycine helps reduce shine appearance without heavy powders.

Capryloyl Glycine is used in anti-blemish spot treatments as a supportive ingredient.
Capryloyl Glycine supports cosmetic blemish care by contributing to a less favorable surface environment for microbes.
Capryloyl Glycine helps improve comfort and reduce greasy feel around spots.

Capryloyl Glycine is used in products designed to support skin microbiome balance concepts.
Capryloyl Glycine supports gentle antimicrobial positioning in cosmetic frameworks.
Capryloyl Glycine helps maintain fresh skin feel while respecting mildness targets.

Capryloyl Glycine is used in deodorant products to help control odor development.
Capryloyl Glycine supports reduction of odor-causing bacteria activity in cosmetic deodorants.
Capryloyl Glycine helps improve freshness perception over wear time.

Capryloyl Glycine is used in roll-on deodorants to support long-lasting odor control.
Capryloyl Glycine supports compatible deodorant systems alongside zinc salts and glycols.
Capryloyl Glycine helps maintain a clean skin feel underarms.

Capryloyl Glycine is used in deodorant creams and sticks as an odor-control supporting active.
Capryloyl Glycine helps reduce unpleasant odor formation by supporting microbiological control.
Capryloyl Glycine supports smoother skin feel and reduced stickiness perception.

Capryloyl Glycine is used in body washes positioned for odor control and freshness.
Capryloyl Glycine supports deodorizing body cleanser concepts for daily use.
Capryloyl Glycine helps maintain fresh feel after showering.

Capryloyl Glycine is used in intimate hygiene cleansers where gentle deodorizing support is desired.
Capryloyl Glycine supports freshness concepts while maintaining mild formulation goals.
Capryloyl Glycine helps reduce unpleasant odor perception in intimate care routines.

Capryloyl Glycine is used in foot care products to help manage odor and comfort.
Capryloyl Glycine supports odor-control foot sprays and foot creams.
Capryloyl Glycine helps reduce odor-causing microbial activity on feet in cosmetic use.

Capryloyl Glycine is used in anti-odor shoe and sock sprays as a cosmetic deodorizing ingredient.
Capryloyl Glycine supports freshening sprays aimed at reducing malodor sources.
Capryloyl Glycine helps improve consumer perception of cleanliness and freshness.

Capryloyl Glycine is used in scalp-care products to support oily scalp management.
Capryloyl Glycine supports scalp fresh-feel and sebum-control concepts in shampoos.
Capryloyl Glycine helps reduce greasy scalp appearance between washes.

Capryloyl Glycine is used in anti-dandruff-support shampoos as a complementary antimicrobial ingredient.
Capryloyl Glycine supports scalp balance concepts alongside recognized dandruff actives.
Capryloyl Glycine helps improve scalp comfort and cleanliness perception.

Capryloyl Glycine is used in hair tonics for oily scalp to support fresh scalp feel.
Capryloyl Glycine supports leave-on scalp care concepts where mild antimicrobial support is desired.
Capryloyl Glycine helps reduce oily look at the hair roots.

Capryloyl Glycine is used in men’s grooming products aimed at controlling shine and odor.
Capryloyl Glycine supports face and body products designed for fresh, matte finish.
Capryloyl Glycine helps improve sensory feel in quick routines.

Capryloyl Glycine is used in teen skin care lines to support blemish-prone skin routines.
Capryloyl Glycine supports daily-use products that aim for gentle oil control.
Capryloyl Glycine helps reduce greasy feel without harsh stripping.

Capryloyl Glycine is used in cosmetic preservative booster concepts in certain systems.
Capryloyl Glycine supports microbial control strategy by reducing microbial growth potential on skin and in product.
Capryloyl Glycine helps improve robustness of mild preservation approaches when compatible.

Capryloyl Glycine is used in emulsions to support stability and improved skin feel in oily-skin products.
Capryloyl Glycine supports lighter textures and reduced tack perception.
Capryloyl Glycine helps improve elegance of gels and lotions.

Capryloyl Glycine is used in cosmetic ingredient blends targeting acne, odor, and sebum control.
Capryloyl Glycine supports multi-benefit blends with zinc salts, glycols, and botanical extracts.
Capryloyl Glycine helps improve performance by combining conditioning and antimicrobial support.

Capryloyl Glycine is used in formulation R&D to reduce surfactant harshness perception while keeping a clean finish.
Capryloyl Glycine supports improved sensorial balance in purifying cleansers.
Capryloyl Glycine helps maintain comfort in daily cleansing routines.

Capryloyl Glycine is used in quality control testing to evaluate odor control performance in deodorant prototypes.
Capryloyl Glycine supports wear tests that measure malodor reduction over time.
Capryloyl Glycine helps improve consumer panel outcomes when used at optimized dosage.

Capryloyl Glycine is used in stability testing of deodorant and oily-skin formulations to ensure efficacy over shelf life.
Capryloyl Glycine supports performance consistency across temperature cycling.
Capryloyl Glycine helps maintain stable appearance and sensory properties during storage.

Capryloyl Glycine is used in cosmetic products designed for humid climates where sweat and odor are common concerns.
Capryloyl Glycine supports freshness and odor management positioning for daily life.
Capryloyl Glycine helps maintain clean feel in challenging conditions.

Capryloyl Glycine is used in activewear body sprays to support odor control after sports.
Capryloyl Glycine supports quick refresh concepts without heavy fragrance.
Capryloyl Glycine helps reduce malodor perception between showers.

Capryloyl Glycine is used in anti-odor wipes for travel and on-the-go hygiene.
Capryloyl Glycine supports portable cleansing and deodorizing routines.
Capryloyl Glycine helps maintain freshness when water is not available.

Capryloyl Glycine is used in facial sheet mask essences aimed at balancing oily skin.
Capryloyl Glycine supports oil-control and fresh-feel mask positioning.
Capryloyl Glycine helps improve skin feel after mask removal.

Capryloyl Glycine is used in post-shave products to support fresh skin feel and reduce odor concerns.
Capryloyl Glycine supports grooming products that aim to minimize irritation while staying fresh.
Capryloyl Glycine helps reduce greasy after-feel in aftershaves and balms.

DESCRIPTION

Capryloyl Glycine is an amphiphilic lipoamino acid that combines a fatty acid chain with the glycine amino acid, and this structure gives Capryloyl Glycine surface-active and skin-interacting behavior.
Capryloyl Glycine is typically supplied as a powder or granules and is used at low levels, with performance strongly influenced by formulation pH and solubilization strategy.
Capryloyl Glycine can help support a skin environment that is less favorable for certain microorganisms associated with odor and blemish-prone conditions, contributing to improved freshness perception.

Capryloyl Glycine is often positioned for oily and acne-prone skin because Capryloyl Glycine supports sebum-balancing concepts and helps reduce the appearance of shine.
Capryloyl Glycine can complement exfoliating acids, zinc salts, niacinamide, and mild surfactant systems, but compatibility and stability testing should be performed.
Capryloyl Glycine may require neutralization or pH adjustment for optimal solubility in water-based systems, and clear solutions depend on the full formulation design.

Capryloyl Glycine should be stored in tightly closed containers in a cool, dry place to prevent moisture pickup and maintain flowability.
Capryloyl Glycine should be handled with appropriate PPE to avoid dust inhalation and unnecessary eye contact during manufacturing.
Capryloyl Glycine should be used according to applicable cosmetic regulations and supplier specifications for purity and intended use.

PROPERTIES

Chemical Formula: C10H19NO3
Molecular Weight: 201.26 g/mol
Common Name: Capryloyl Glycine
Chemical Type: Lipoamino acid (fatty acyl amino acid derivative)
Appearance: White to off-white powder or granules
Odor: Mild characteristic odor
Solubility: Limited solubility in water; solubility improves with pH adjustment and suitable solubilizers (system dependent)
pH Use Range: Often formulated in mildly acidic to neutral ranges (performance dependent)
Surface Activity: Amphiphilic character supports mild surface activity and interface behavior
Deodorant Support: Helps reduce malodor by supporting control of odor-associated microorganisms (formulation dependent)
Sebum Control Concept: Supports reduced shine and improved skin feel in oily-skin routines (formulation dependent)
Stability: Generally stable under recommended storage; avoid strong oxidizers and extreme pH conditions
Storage Temperature: 15–25°C, dry, tightly closed
Shelf Life: Typically 24 months in original sealed packaging (supplier dependent)

FIRST AID

Inhalation:
Move to fresh air if dust is inhaled.
Seek medical attention if respiratory irritation persists.
Avoid breathing dust during handling and powder charging.

Skin Contact:
Wash with soap and water after contact.
Remove contaminated clothing and wash before reuse.
Seek medical advice if irritation develops or persists.

Eye Contact:
Rinse cautiously with water for several minutes.
Remove contact lenses if present and easy to do, then continue rinsing.
Seek medical attention if irritation persists.

Ingestion:
Rinse mouth with water.
Seek medical attention if discomfort occurs or if a significant amount is swallowed.
Never give anything by mouth to an unconscious person.

Note to Physicians:
Treat symptomatically.
No specific antidote is required.
Provide supportive care based on exposure route and symptoms.

HANDLING AND STORAGE

Handling:
Use appropriate PPE including gloves and safety glasses, and use dust protection as needed.
Avoid generating dust and avoid inhalation of fine powder.
Wash hands after handling and before eating, drinking, or smoking.

Ventilation:
Use local exhaust or general ventilation where dust may be generated.
Maintain good airflow during weighing, charging, and blending operations.
Minimize airborne particulate accumulation in enclosed areas.

Storage:
Store in tightly closed containers in a cool, dry place.
Protect from moisture to prevent caking and maintain consistent solubility behavior.
Keep containers properly labeled and protected from contamination.

Spill and Leak Procedures:
Avoid dust generation and sweep or vacuum using equipment designed for fine powders.
Place collected material into suitable containers for disposal according to local regulations.
Clean the area with wet wiping if needed to remove residues and reduce dust dispersion.

Handling Precautions:
Optimize formulation pH and solubilization approach to achieve uniform distribution and consistent performance of Capryloyl Glycine.
Conduct stability and microbiological testing on finished products to confirm efficacy within the intended use conditions.
Rotate stock using FIFO practices to maintain consistent quality and predictable formulation behavior.