CARBOWAX POLYETHYLENE GLYCOL 8000

CARBOWAX Polyethylene Glycol 8000 is a polymer which is hydrolyzed by ethylene oxide. 
CARBOWAX Polyethylene Glycol 8000 is soluble in water (500 g/l at 20° C), aromatic hydrocarbons (very soluble), aliphatic hydrocarbons (slightly soluble), and organic solvents.
CARBOWAX Polyethylene Glycol 8000 is suitable as a medium for the fusion of mammalian cells.

CAS Number: 25322-68-3
EINECS Number: 500-038-2

25322-68-3, POLYETHYLENEGLYCOL 6000, 2-ethanediyl),.alpha.-hydro-.omega.-hydroxy-Poly(oxy-1;Alcox E 160;Alcox E 30;Poly(ethylene oxide),approx. M.W. 900,000;CARBOWAX Polyethylene Glycol 8000 1550PRACT.;Poly(ethylene glycol),Macrogol 35,000, PEG;Poly(ethylene glycol),Macrogol 3,000, PEG;Poly(ethylene glycol),Macrogol 300, PEG

CARBOWAX Polyethylene Glycol 8000 is a water-soluble, waxy solid that is used extensively in the several industries.
CARBOWAX Polyethylene Glycol 8000 is a CARBOWAX Polyethylene Glycol 8000 having white to off white color and available in solid flakes or powder form.
CARBOWAX Polyethylene Glycol 8000 used as a base in the formulation of soap sticks.

CARBOWAX Polyethylene Glycol 8000 has a wide range of uses including cell fusion for the formation of hybridomas, precipitation of DNA, and to create macromolecular crowding in solutions.
The toxicity of low molecular weight CARBOWAX Polyethylene Glycol 8000 is relatively large. 
In general, the toxicity of diols is very low. 

Topical application of CARBOWAX Polyethylene Glycol 8000, especially mucosal drug, can cause irritant pain. 
In topical lotion, this product can increase the flexibility of the skin, and has a similar moisturizing effect with glycerin. 
The high molecular weight PEG 8000 is soluble in water and organic solvents such as alcohols. 

CARBOWAX Polyethylene Glycol 8000 can blend with other PEG molecular weights to achieve the desired viscosity properties. 
CARBOWAX Polyethylene Glycol 8000 is quite stable and does not support microbial growth, even in aqueous solutions.
Ultrapure white crystals for molecular biology applications such as precipitation of DNA, nucleic acids, hybridization and fusion of mammalian cells.

Working concentrations of CARBOWAX Polyethylene Glycol 8000 range from 13% to 40% (w/v).
Prepare the appropriate concentration by dissolving CARBOWAX Polyethylene Glycol 8000 in sterile H2O, warming if necessary.
Sterilize the solution by passing CARBOWAX Polyethylene Glycol 8000 through a 0.22-μm filter.

CARBOWAX Polyethylene Glycol 8000 has low glycol content and higher crystalinity.
The high molecular weight CARBOWAX Polyethylene Glycol 8000 is soluble in water and organic solvents such as alcohols.
CARBOWAX Polyethylene Glycol 8000 can blend with other PEG molecular weights to achieve the desired viscosity properties.

Ultrapure white crystals for molecular biology applications such as precipitation of DNA, nucleic acids, hybridization and fusion of mammalian cells
CARBOWAX Polyethylene Glycol 8000 (PEG) is a polyether compound with many applications from industrial manufacturing to medicine.
CARBOWAX Polyethylene Glycol 8000 by Dow is PEG-180-based mold release agent and plasticizer. 

CARBOWAX Polyethylene Glycol 8000 possesses lubricity and humectant properties.
CARBOWAX Polyethylene Glycol 8000 maintains wet-tack strength and is used in pressure sensitive and thermoplastic adhesives.

CARBOWAX Polyethylene Glycol 8000 meets the requirements for use under food additive regulations for indirect use as components of articles intended for use in contact with food.
CARBOWAX Polyethylene Glycol 8000 cross-linked polymeric materials (hydrogels) are suitable carriers for drug delivery and various other biomedical applications.
CARBOWAX Polyethylene Glycol 8000 is a long-chain hydrophilic, crosslinking monomer. 

CARBOWAX Polyethylene Glycol 8000 structure forms a crystalline thermoplastic polyether that is practically water-soluble in applicable concentrations and exhibits very low immunogenicity, antigenicity and toxicity. 
CARBOWAX Polyethylene Glycol 8000 structure is a hydrophilic molecule, having high flexibility. 
The excellent aqueous solubility of CARBOWAX Polyethylene Glycol 8000 is due to the distance of the oxygens in the glycol structure that is similar with the distance of the hydrogens in the water molecule. 

This property is unique to CARBOWAX Polyethylene Glycol 8000s among all other aliphatic polyethers which are commonly not water-soluble.
Most CARBOWAX Polyethylene Glycol 8000 differ only in their molecular weights, hydroxyl numbers and viscosity profiles. 
CARBOWAX Polyethylene Glycol 8000 are named based on the number of units of ethylene glycol, or on their molecular weights. 

Low molecular weight CARBOWAX Polyethylene Glycol 8000 are in the liquid state, average molecular weight CARBOWAX Polyethylene Glycol 8000 appear as semisolids or waxy solids, while higher molecular CARBOWAX Polyethylene Glycol 8000 exist as waxy or crystalline solids in flake or powder form.
CARBOWAX Polyethylene Glycol 8000 is the most biocompatible polymer having applications in fields like pharmaceuticals, medical for tablet film coating formulations, laxatives, food additives & cosmetics. 
In the cosmetic field, CARBOWAX Polyethylene Glycol 8000 are used widely in skin care products combined with glycerin. 

The application of CARBOWAX Polyethylene Glycol 8000, which is important for skin creams, ointments, and suppositories, depends on the melting point of CARBOWAX Polyethylene Glycol 8000 which depends on the chain length. 
The high molecular weight CARBOWAX Polyethylene Glycol 8000 have approximate melting point ~ 65 °C while lower molecular weight CARBOWAX Polyethylene Glycol 8000 are liquids. 
CARBOWAX Polyethylene Glycol 8000 can be custom-made in the physiological temperature range (36.1 - 37.2 °C) by blending different molecular weights. 

CARBOWAX Polyethylene Glycol 8000 is sold and marketed by several companies under well known trade names that are established for medical, cosmetic, and pharmaceutical purposes.
Pharmaceutical formulations and cosmetics use CARBOWAX Polyethylene Glycol 8000 with smaller molecular weights. 
The lower the molecular weight, it helps the active compounds to penetrate the skin. 

In cosmetic application, CARBOWAX Polyethylene Glycol 8000 can function in three different ways: as emollients which helps to soften and lubricate the skin; as emulsifiers which help mix water- and oil-based ingredients thoroughly, and as delivery vehicles that help transport other ingredients deeper into the skin.
CARBOWAX Polyethylene Glycol 8000 (PEG) is the most widely used “stealth” polymer in the drug delivery field, due to its long history of safety in humans and classification as Generally Regarded as Safe (GRAS) by the FDA. 
US FDA’s Inactive Ingredient Guide (IIG) (or Inactive Ingredient Database (IID)) lists the use of CARBOWAX Polyethylene Glycol 8000 and their maximum concentration in oral, topical, and intravenous formulations.

In the medical field, PEGylating proteins allows to evade the immune system and thereby prolong circulation lifetimes and decrease immunogenicity (the ability of a foreign substance, to provoke an immune response in the human body). 
Similarly, coating the surface of nanoparticles with CARBOWAX Polyethylene Glycol 8000 (PEG), or “PEGylation”, is a commonly used approach for improving the efficiency of drug and gene delivery to target cells and tissues. 
The FDA approved the first PEGylated nanoparticle (NP) product, CARBOWAX Polyethylene Glycol 8000, in 1995. 

These Doxil “Stealth” liposomes increased doxorubicin (anticancer drug) bioavailability nearly 90-fold at 1 week from injection versus free drug, with a drug half-life of 72 h and circulation half-life of 36 h. 
CARBOWAX Polyethylene Glycol 8000 has been demonstrated that PEG MW of 2 kDa or higher is required to shield NP surfaces from protein adsorption and reduce recognition by the mononuclear phagocyte system (MPS).
The main ingredient in anti-freeze formulation is CARBOWAX Polyethylene Glycol 8000.

CARBOWAX Polyethylene Glycol 8000 maintains wet-tack strength and is used in pressure sensitive and thermoplastic adhesives.
CARBOWAX Polyethylene Glycol 8000 is a water-soluble linear polymer formed by the addition reaction of ethylene oxide.
CARBOWAX Polyethylene Glycol 8000 is sold as a solid in bags or in fiber drums.

The containers should be kept sealed and should not be stored next to steam lines or other heat sources that could cause the product to soften or melt.
Recommended storage temperature is below 40°C (105°F).
CARBOWAX Polyethylene Glycol 8000 is a polyether compound derived from petroleum with many applications, from industrial manufacturing to medicine.

CARBOWAX Polyethylene Glycol 8000 is also known as polyethylene oxide (PEO) or polyoxyethylene (POE), depending on its molecular weight.
The structure of CARBOWAX Polyethylene Glycol 8000 is commonly expressed as H−(O−CH2−CH2)n−OH.
CARBOWAX Polyethylene Glycol 8000 are a family of linear polymers formed by a base-catalyzed condensation reaction with repeating ethylene oxide units being added to ethylene.

The molecular formula is (C2H4O) multH2O where mult denotes the average number of oxyethylene groups.
The molecular weight can range from 200 to several million corresponding to the number of oxyethylene groups.
The higher-molecular-weight materials (100 000 to 5 000 000) are also referred to as polyethylene oxides.

The average molecular weight of any specific CARBOWAX Polyethylene Glycol 8000 product falls within quite narrow limits (°5%).
The number of ethylene oxide units or their approximate molecular weight (e.g., PEG-4 or PEG-200) commonly designates the nomenclature of specific CARBOWAX Polyethylene Glycol 8000.
CARBOWAX Polyethylene Glycol 8000 with amolecular weight less than 600 are liquid, whereas those of molecular weight 1000 and above are solid.

CARBOWAX Polyethylene Glycol 8000 is quite stable and does not support microbial growth, even in aqueous solutions.
Diarrhoea can occur in large doses of oral administration. 
In injection, the maximum CARBOWAX Polyethylene Glycol 8000 300 concentration is about 30% (V/V). 

Hemolysis could occur when the concentration is more than 40% (V/V).
The CARBOWAX Polyethylene Glycol 8000 solution is applied to the outer layer of the pill to control the diffusion of drugs in the pill so as to improve the efficacy.
Surface modification of medical polymer materials. 

The biocompatibility of medical polymer materials in contact with blood can be improved by adsorption, interception and grafting of two amphiphilic copolymers containing CARBOWAX Polyethylene Glycol 8000 on the surface of medical polymers.
CARBOWAX Polyethylene Glycol 8000 can make the membrane of the alkanol contraceptive pill.
CARBOWAX Polyethylene Glycol 8000 can make hydrophilic anticoagulant polyurethane.

CARBOWAX Polyethylene Glycol 8000 is an osmotic laxative. 
CARBOWAX Polyethylene Glycol 8000 can increase osmotic pressure and absorb moisture in the intestinal cavity, which makes the stool soften and increase in volume, resulting in bowel movement and defecation.
Peg nontoxic and gelatinous nature can be used as a component of denture fixer.

PEG 4000 and PEG 6000 are commonly used to promote cell fusion or protoplast fusion and help organisms (such as yeasts) to take DNA in transformation. 
CARBOWAX Polyethylene Glycol 8000 absorbs water from the solution, so it is also used to concentrate the solution.
CARBOWAX Polyethylene Glycol 8000 is PEG-180-based mold release agent and plasticizer.

CARBOWAX Polyethylene Glycol 8000 possesses lubricity and humectant properties.
CARBOWAX Polyethylene Glycol 8000 meets the requirements for use under food additive regulations for indirect use as components of articles intended for use in contact with food.
CARBOWAX Polyethylene Glycol 8000 is used in the modification of therapeutic proteins and peptides to enhance its solubility. 

CARBOWAX Polyethylene Glycol 8000 is also used in the fabrication of bioactive and immuno isolating barriers for encapsulation of cells. 
In gas chromatography, CARBOWAX Polyethylene Glycol 8000 is used as a polar stationary phase. 
CARBOWAX Polyethylene Glycol 8000 is used as mold release agent and lubricant in fabricating elastomers. 

As a dispersant, it is used in toothpastes. 
CARBOWAX Polyethylene Glycol 8000 finds application in blood banking as a potentiator, which is used to detect antigens and antibodies. 
In pharmaceutical industry, it is used as tablet and capsule lubricant.

High-molecular weight CARBOWAX Polyethylene Glycol 8000 that provides enhanced solvency, lubricity, hygroscopicity and other important functional properties in a wide range of formulations.
CARBOWAX Polyethylene Glycol 8000 is a compound used to modify therapeutic proteins and peptides to increase their solubility. 
CARBOWAX Polyethylene Glycol 8000 is often utilized in mass spectrometry experiments and as a polar stationary phase for Gas Chromatorgraphy. 

CARBOWAX Polyethylene Glycol 8000 is also used to preserve objects that have been retrieved from the ocean. 
In fabricating elastomers, it functions as a lubricant and mold releasing agent. 
In pharmaceuticals, CARBOWAX Polyethylene Glycol 8000 can function as a tablet and capsule lubricant.

CARBOWAX Polyethylene Glycol 8000, a hydrophilic polymer, is easily synthesized by the anionic ring opening polymerization of ethylene oxide, into a range molecular weights and variety of end groups. 
On being incorporated into networks by crosslinking, CARBOWAX Polyethylene Glycol 8000 can have high water content, forming “hydrogels”. 
Hydrogel formation can be initiated by either crosslinking PEG by ionizing radiation or by covalent crosslinking of PEG macromers with reactive chain ends. 

CARBOWAX Polyethylene Glycol 8000 is a suitable compound with a wide scope in biological applications since it does not elicit any immune responses. 
CARBOWAX Polyethylene Glycol 8000 has been shown to modify therapeutic proteins and peptides for enhanced solubility. 
Additionally, photopolymerized PEG hydrogels have emerging applications in the fabrication of bioactive and immune-isolating barriers for encapsulation of cells. 

CARBOWAX Polyethylene Glycol 8000 is also used as a fusogen (induces cell hybridization) to obtain hybridomas for monoclonal antibody production.
CARBOWAX Polyethylene Glycol 8000 is a CARBOWAX Polyethylene Glycol 8000 having white to off white color and available in solid flakes or powder form. 
CARBOWAX Polyethylene Glycol 8000 used as a base in the formulation of soap sticks. PEG 8000 has low glycol content and higher crystalinity. 

Its high molecular weight mainly prompts its use in pharmaceutical formulations as solvent for oral, topical and parenteral preparations.
CARBOWAX Polyethylene Glycol 8000s are a family of linear polymers formed by a base-catalyzed condensation reaction with repeating ethylene oxide units being added to ethylene. 
The molecular formula is (C2H4O)multH2O where mult denotes the average number of oxyethylene groups. 

The molecular weight can range from 200 to several million corresponding to the number of oxyethylene groups. 
The higher-molecular-weight materials (100 000 to 5 000 000) are also referred to as polyethylene oxides. 
The average molecular weight of any specific CARBOWAX Polyethylene Glycol 8000 product falls within quite narrow limits (°5%). 

The number of ethylene oxide units or their approximate molecular weight (e.g., PEG-4 or PEG-200) commonly designates the nomenclature of specific CARBOWAX Polyethylene Glycol 8000s. 
CARBOWAX Polyethylene Glycol 8000s with amolecular weight less than 600 are liquid, whereas those of molecular weight 1000 and above are solid. 
These materials are nonvolatile, water-soluble, tasteless, and odorless. 

They are miscible with water, alcohols, esters, ketones, aromatic solvents, and chlorinated hydrocarbons, but immiscible with alkanes, paraffins, waxes, and ethers.
CARBOWAX Polyethylene Glycol 8000 is also known as polyoxirane (PEO). 
CARBOWAX Polyethylene Glycol 8000 is a linear polyether obtained by ring opening polymerization of ethylene oxide. 

The viscosity of CARBOWAX Polyethylene Glycol 8000 solution is sensitive to the shear rate and it is not easy for bacteria to grow on CARBOWAX Polyethylene Glycol 8000.
The condensation polymer of ethylene oxide and water. 

CARBOWAX Polyethylene Glycol 8000 is a cream matrix for preparing water-soluble drugs. 
CARBOWAX Polyethylene Glycol 8000 can also be used as a solvent for acetylsalicylic acid and caffeine, which is difficult to dissolve in water.
Drug sustained-release and immobilized enzyme carrier. 

CARBOWAX Polyethylene Glycol 8000 has no toxicity and irritation. 
CARBOWAX Polyethylene Glycol 8000 is widely used in various pharmaceutical preparations. 

Melting point: 64-66 °C
Boiling point:>250°C
Density: 1.27 g/mL at 25 °C
vapor density: >1 (vs air)
vapor pressure: <0.01 mm Hg ( 20 °C)
refractive index: n20/D 1.469
Flash point: 270 °C
storage temp: 2-8°C
solubility: H2O: 50 mg/mL, clear, colorless
form: waxy solid
Specific Gravity: 1.128
color: White to very pale yellow
PH: 5.5-7.0 (25℃, 50mg/mL in H2O)
Water Solubility: Soluble in water.
Sensitive: Hygroscopic
λmax: λ: 260 nm Amax: 0.6
λ: 280 nm Amax: 0.3
Merck: 14,7568
Stability: Stable. Incompatible with strong oxidizing agents.
LogP: -0.698 at 25℃

CARBOWAX Polyethylene Glycol 8000 are used in drug delivery systems because they are neutral, nontoxic, and water soluble and can form micelles which are biocompatible and biodegradable.
CARBOWAX Polyethylene Glycol 8000 is generally used in the precipitation of phage.
CARBOWAX Polyethylene Glycol 8000 is used for the isolation of plasmid DNA and the precipitation of phage.

CARBOWAX Polyethylene Glycol 8000 is used as matrix in pharmaceutical and cosmetic industry to regulate viscosity and melting point.
CARBOWAX Polyethylene Glycol 8000 is used as lubricant and coolant in rubber and metal processing industry, dispersant and emulsifier in pesticide and pigment industry production.
CARBOWAX Polyethylene Glycol 8000 is used as antistatic agent and lubricant in textile industry.

CARBOWAX Polyethylene Glycol 8000 (PEG 8000) is a safe solvent and carrier for use in cosmetics can act as a solvent in many substances.
CARBOWAX Polyethylene Glycol 8000 is also a secure carrier.
CARBOWAX Polyethylene Glycol 8000 is also used as a fusogen (induces cell hybridization) to obtain hybridomas for monoclonal antibody production.

Additionally, photopolymerized CARBOWAX Polyethylene Glycol 8000 hydrogels have emerging applications in the fabrication of bioactive and immune-isolating barriers for encapsulation of cells.
CARBOWAX Polyethylene Glycol 8000 is a suitable compound with a wide scope in biological applications since CARBOWAX Polyethylene Glycol 8000 does not elicit any immune responses.
CARBOWAX Polyethylene Glycol 8000 has been shown to modify therapeutic proteins and peptides for enhanced solubility.

CARBOWAX Polyethylene Glycol 8000 is vastly used for the isolation of plasmid DNA and the precipitation of phage.
CARBOWAX Polyethylene Glycol 8000 is a polymer which is hydrolyzed by ethylene oxide.
CARBOWAX Polyethylene Glycol 8000 has no toxicity and irritation.

CARBOWAX Polyethylene Glycol 8000 is widely used in various pharmaceutical preparations.
The toxicity of low molecular weight CARBOWAX Polyethylene Glycol 8000 is relatively large.
In general, the toxicity of diols is very low.

Topical application of CARBOWAX Polyethylene Glycol 8000, especially mucosal drug, can cause irritant pain.
In topical lotion, CARBOWAX Polyethylene Glycol 8000 can increase the flexibility of the skin, and has a similar moisturizing effect with glycerin.
CARBOWAX Polyethylene Glycol 8000 can occur in large doses of oral administration.

In injection, the maximum CARBOWAX Polyethylene Glycol 8000 concentration is about 30% (V/V).
Hemolysis could occur when the concentration is more than 40% (V/V).
The USP32–NF27 describes CARBOWAX Polyethylene Glycol 8000 as being an addition polymer of ethylene oxide and water.

CARBOWAX Polyethylene Glycol 8000 are liquids; grades 1000 and above are solids at ambient temperatures.
CARBOWAX Polyethylene Glycol 8000 occur as clear, colorless or slightly yellow-colored, viscous liquids.
They have a slight but characteristic odor and a bitter, slightly burning taste.

CARBOWAX Polyethylene Glycol 8000 can occur as a solid at ambient temperatures.
CARBOWAX Polyethylene Glycol 8000 are white or off-white in color, and range in consistency from pastes to waxy flakes.
Grades of CARBOWAX Polyethylene Glycol 8000 and above are available as freeflowing milled powders.

CARBOWAX Polyethylene Glycol 8000 have the following disadvantages: they are chemically more reactive than fats; greater care is needed in processing to avoid inelegant contraction holes in the suppositories; the rate of release of water-soluble medications decreases with the increasing molecular weight of the CARBOWAX Polyethylene Glycol 8000; and CARBOWAX Polyethylene Glycol 8000s tend to be more irritating to mucous membranes than fats.
CARBOWAX Polyethylene Glycol 8000 can be used either as suspending agents or to adjust the viscosity and consistency of other suspending vehicles.
When used in conjunction with other emulsifiers, CARBOWAX Polyethylene Glycol 8000 can act as emulsion stabilizers.

CARBOWAX Polyethylene Glycol 8000 are used as water-miscible solvents for the contents of soft gelatin capsules.
However, they may cause hardening of the capsule shell by preferential absorption of moisture from gelatin in the shell.
In concentrations up to approximately 30% v/v, PEG 300 and PEG 400 have been used as the vehicle for parenteral dosage forms.

In solid-dosage formulations, higher-molecular-weight CARBOWAX Polyethylene Glycol 8000 can enhance the effectiveness of tablet binders and impart plasticity to granules.
However, they have only limited binding action when used alone, and can prolong disintegration if present in concentrations greater than 5% w/w.
When used for thermoplastic granulations,a mixture of the powdered constituents with 10–15% w/w CARBOWAX Polyethylene Glycol 8000 is heated to 70–75°C.

The mass becomes pastelike and forms granules if stirred while cooling.
This technique is useful for the preparation of dosage forms such as lozenges when prolonged disintegration is required.
CARBOWAX Polyethylene Glycol 8000 can also be used to enhance the aqueous solubility or dissolution characteristics of poorly soluble compounds by making solid dispersions with an appropriate CARBOWAX Polyethylene Glycol 8000.

Animal studies have also been performed using CARBOWAX Polyethylene Glycol 8000 as solvents for steroids in osmotic pumps.
In film coatings, solid grades of CARBOWAX Polyethylene Glycol 8000 can be used alone for the film-coating of tablets or can be useful as hydrophilic polishing materials.
Solid grades are also widely used as plasticizers in conjunction with film-forming polymers.

The presence of CARBOWAX Polyethylene Glycol 8000 in film coats, especially of liquid grades, tends to increase their water permeability and may reduce protection against low pH in enteric-coating films.
CARBOWAX Polyethylene Glycol 8000 are useful as plasticizers in microencapsulated products to avoid rupture of the coating film when the microcapsules are compressed into tablets.
CARBOWAX Polyethylene Glycol 8000 grades with molecular weights of 8000 and above can be used as lubricants, particularly for soluble tablets.

CARBOWAX Polyethylene Glycol 8000 are useful in detergent formulations as antideposition agents. 
CARBOWAX Polyethylene Glycol 8000 is a highly effective anti-redeposition agent on both polyester fabrics, synthetic-cellulose garments and polyester-cotton fabrics. 
Secondly, CARBOWAX Polyethylene Glycol 8000 are used as binder in powder formulations to effectively ensure that all the components are held together as granules. 

The choice of high or low melting CARBOWAX Polyethylene Glycol 8000 to be added in the formulation is usually done based on the ambient temperature where the powder detergent product will be distributed or sold. 
Apart from the above mentioned application or uses of glycol, based on their non-toxic nature, CARBOWAX Polyethylene Glycol 8000 also are non-corrosive. 
Therefore, they can be comfortably used in contact with materials like, rubber, plastic, metals, textiles without causing damage or staining. 

CARBOWAX Polyethylene Glycol 8000 do not support microbial growth (resistance to mould growth) and rancidity hence an ideal excipient for liquid dosage forms.
CARBOWAX Polyethylene Glycol 8000 is used as mold release agent and lubricant in fabricating elastomers.
CARBOWAX Polyethylene Glycol 8000 resins are high molecular weight homopolymers of ethylene oxide via heterogeneously catalyzed ringopening polymerization.

Usually can be divided into the relative molecular mass of 2 × 1 04 above and tens of thousands of above, the former is called CARBOWAX Polyethylene Glycol 8000, the latter is called polyethylene oxide.
CARBOWAX Polyethylene Glycol 8000 with flocculation, thickening, slow release, lubrication, dispersion, retention, water retention and other properties, suitable for medicine, fertilizer, paper, ceramics, detergents, cosmetics, heat treatment, water treatment, fire, oil exploitation and other industries, the product is non-toxic and non-irritating, and will not remain, deposit or breed volatile matter in the process of product generation.
As a papermaking additive, the retention rate of the filler and the fine fiber can be improved, and the dispersant is particularly suitable for the long fiber, and the beating time can be shortened.

CARBOWAX Polyethylene Glycol 8000's high molecular weight mainly prompts CARBOWAX Polyethylene Glycol 8000's use in pharmaceutical formulations as solvent for oral, topical and parenteral preparations.
CARBOWAX Polyethylene Glycol 8000 that has wide application ranging from industrial manufacturing and medicine.
CARBOWAX Polyethylene Glycol 8000 is a compound used to modify therapeutic proteins and peptides to increase their solubility.

CARBOWAX Polyethylene Glycol 8000 is also used to precipitate bacteriophage from lysed cell supernatants.
CARBOWAX Polyethylene Glycol 8000 is often used as a polar stationary phase for Gas Chromatorgraphy.
CARBOWAX Polyethylene Glycol 8000 is commonly also used in mass spec experiments.

As a dispersant, CARBOWAX Polyethylene Glycol 8000 is used in toothpastes.
In fabricating elastomers, CARBOWAX Polyethylene Glycol 8000 can be used as a lubricant and mold releasing agent.
In pharmaceuticals, CARBOWAX Polyethylene Glycol 8000 can function as a tablet and capsule lubricant.

CARBOWAX Polyethylene Glycol 8000 are produced to meet the requirements for use under Food Additive Regulations for indirect use as components of articles intended for use in contact with food.
Crystallization grade CARBOWAX Polyethylene Glycol 8000 for formulating screens or for optimization.
CARBOWAX Polyethylene Glycol 8000 is used in the modification of therapeutic proteins and peptides to enhance CARBOWAX Polyethylene Glycol 8000's solubility.

In gas chromatography, CARBOWAX Polyethylene Glycol 8000 is used as a polar stationary phase.
CARBOWAX Polyethylene Glycol 8000 finds application in blood banking as a potentiator, which is used to detect antigens and antibodies.
In pharmaceutical industry, CARBOWAX Polyethylene Glycol 8000 is used as tablet and capsule lubricant.

CARBOWAX Polyethylene Glycol 8000 is also used in the fabrication of bioactive and immuno isolating barriers for encapsulation of cells.
CARBOWAX Polyethylene Glycol 8000, NF acts as a lubricant, coating the surfaces in aqueous and non-aqueous environments.
Research or further manufacturing, CARBOWAX Polyethylene Glycol 8000 is used only, not for food or drug use.

CARBOWAX Polyethylene Glycol 8000 is a colorless, non-volatile, hygroscopic liquid. 
CARBOWAX Polyethylene Glycol 8000 is soluble in water, and organic solvents like acetone, alcohol, benzene, and other glycols. 
Due to it low molecular weight and properties CARBOWAX Polyethylene Glycol 8000-200 has a wide range of potential uses. 

CARBOWAX Polyethylene Glycol 8000 200 is used as a defoaming agent, lubricant and viscosity modifier in many different products. 
CARBOWAX Polyethylene Glycol 8000-200 is used as a coating for fresh fruit to preserve their freshness, as a solvent in metal working fluids, heat transfer fluids, as a binder and modifier in latex paints, and as a humectant in inks and abrasives. 
CARBOWAX Polyethylene Glycol 8000 also finds use in formulations of resins, adhesives, as antistatic agent, in chemical intermediates, release agent and plasticizers. 

Specific industries like agriculture, cosmetics, detergents, health and medicine, textiles also rely on CARBOWAX Polyethylene Glycol 8000-200 for its emulsifying and non-corrosive property.
CARBOWAX Polyethylene Glycol 8000 is widely used as a mould release agents and lubricants for rubber industry.
CARBOWAX Polyethylene Glycol 8000 is also used to preserve objects that have been retrieved from the ocean.

CARBOWAX Polyethylene Glycol 8000 can be easily applied and removed since they are water-soluble.
CARBOWAX Polyethylene Glycol 8000 are also used as binder and dry lubricant for manufacturer of pills and tablets for certain pharmaceutical products.

Uses Of CARBOWAX Polyethylene Glycol 8000:
CARBOWAX Polyethylene Glycol 8000 is used in various applications from industrial chemistry to biological chemistry. 
For example, the melting point of the suppository can be made higher to withstand exposure to warmer climates; release of the drug is not dependent upon melting point; the physical stability on storage is better; and suppositories are readily miscible with rectal fluids. 
CARBOWAX Polyethylene Glycol 8000s have the following disadvantages: they are chemically more reactive than fats; greater care is needed in processing to avoid inelegant contraction holes in the suppositories; the rate of release of water-soluble medications decreases with the increasing molecular weight of the CARBOWAX Polyethylene Glycol 8000; and CARBOWAX Polyethylene Glycol 8000s tend to be more irritating to mucous membranes than fats.

Aqueous CARBOWAX Polyethylene Glycol 8000 solutions can be used either as suspending agents or to adjust the viscosity and consistency of other suspending vehicles. 
When used in conjunction with other emulsifiers, CARBOWAX Polyethylene Glycol 8000s can act as emulsion stabilizers. 
Liquid CARBOWAX Polyethylene Glycol 8000s are used as water-miscible solvents for the contents of soft gelatin capsules. 

However, they may cause hardening of the capsule shell by preferential absorption of moisture from gelatin in the shell.
In concentrations up to approximately 30% v/v, PEG 300 and PEG 400 have been used as the vehicle for parenteral dosage forms. 
CARBOWAX Polyethylene Glycol 8000 has also been used in insulin-loaded microparticles for the oral delivery of insulin;it has been used in inhalation preparations to improve aerosolization;CARBOWAX Polyethylene Glycol 8000 nanoparticles have been used to improve the oral bioavailability of cyclosporine;it has been used in self-assembled polymeric nanoparticles as a drug carrier;and copolymer networks of CARBOWAX Polyethylene Glycol 8000 grafted with poly(methacrylic acid) have been used as bioadhesive controlled drug 
delivery formulations.

CARBOWAX Polyethylene Glycol 8000 is also known as polyoxirane (PEO).
CARBOWAX Polyethylene Glycol 8000 is a linear polyether obtained by ring opening polymerization of ethylene oxide.
The viscosity of CARBOWAX Polyethylene Glycol 8000 solution is sensitive to the shear rate and it is not easy for bacteria to grow on CARBOWAX Polyethylene Glycol 8000.

The condensation polymer of ethylene oxide and water.
CARBOWAX Polyethylene Glycol 8000 is a cream matrix for preparing water-soluble drugs.
CARBOWAX Polyethylene Glycol 8000 can also be used as a solvent for acetylsalicylic acid and caffeine, which is difficult to dissolve in water.

A nitrate ester-plasticized CARBOWAX Polyethylene Glycol 8000 (NEPE-75) is used in Trident II submarine-launched ballistic missile solid rocket fuel.
Dimethyl ethers of CARBOWAX Polyethylene Glycol 8000 are the key ingredient of Selexol, a solvent used by coal-burning,
integrated gasification combined cycle (IGCC) power plants to remove carbon dioxide and hydrogen sulfide from the syngas stream.

CARBOWAX Polyethylene Glycol 8000 has been used as the gate insulator in an electric double-layer transistor to induce superconductivity in an insulator.
CARBOWAX Polyethylene Glycol 8000is also used as a polymer host for solid polymer electrolytes.
Although not yet in commercial production, many groups around the globe are engaged in research on solid polymer electrolytes involving CARBOWAX Polyethylene Glycol 8000, with the aim of improving their properties, and in permitting their use in batteries, electro-chromic display systems, and other products in the future.

CARBOWAX Polyethylene Glycol 8000 is injected into industrial processes to reduce foaming in separation equipment.
CARBOWAX Polyethylene Glycol 8000 is used as a binder in the preparation of technical ceramics.
CARBOWAX Polyethylene Glycol 8000 was used as an additive to silver halide photographic emulsions.

​Used in a variety of applications such as wood treating, adhesives, ceramic binder, chemical intermediates, detergents and household cleaners, dye carrier, lubricants, and mining.​​
In solid-dosage formulations, higher-molecular-weight CARBOWAX Polyethylene Glycol 8000s can enhance the effectiveness of tablet binders and impart plasticity to granules.
However, they have only limited binding action when used alone, and can prolong disintegration if present in concentrations greater than 5% w/w. 

When used for thermoplastic granulations,a mixture of the powdered constituents with 10–15% w/w PEG 6000 is heated to 70–75°C. 
The mass becomes pastelike and forms granules if stirred while cooling. 
This technique is useful for the preparation of dosage forms such as lozenges when prolonged disintegration is required. 

CARBOWAX Polyethylene Glycol 8000s can also be used to enhance the aqueous solubility or dissolution characteristics of poorly soluble compounds by making solid dispersions with an appropriate CARBOWAX Polyethylene Glycol 8000.
Animal studies have also been performed using CARBOWAX Polyethylene Glycol 8000s as solvents for steroids in osmotic pumps. 
In film coatings, solid grades of CARBOWAX Polyethylene Glycol 8000 can be used alone for the film-coating of tablets or can be useful as hydrophilic polishing materials. 

Solid grades are also widely used as plasticizers in conjunction with film-forming polymers.
The presence of CARBOWAX Polyethylene Glycol 8000s in film coats, especially of liquid grades, tends to increase their water permeability and may reduce protection against low pH in enteric-coating films. 
CARBOWAX Polyethylene Glycol 8000s are useful as plasticizers in microencapsulated products to avoid rupture of the coating film when the microcapsules are compressed into tablets.

CARBOWAX Polyethylene Glycol 8000 grades with molecular weights of 6000 and above can be used as lubricants, particularly for soluble tablets. 
The lubricant action is not as good as that of magnesium stearate, and stickiness may develop if the material becomes too warm during compression. 
An antiadherent effect is also exerted, again subject to the avoidance of overheating.

Recent research has shown CARBOWAX Polyethylene Glycol 8000 m aintains the ability to aid the spinal cord injury recovery process, helping the nerve impulse conduction process in animals. 
In rats, CARBOWAX Polyethylene Glycol 8000 has been shown to aid in the repair of severed sciatic axons, helping with nerve damage recovery. 
CARBOWAX Polyethylene Glycol 8000 is industrially produced as a lubricating substance for various surfaces to reduce friction. 

CARBOWAX Polyethylene Glycol 8000 is also used in the preparation of vesicle transport systems in with application towards diagnostic procedures or drug delivery methods.
CARBOWAX Polyethylene Glycol 8000 solution is applied to the outer layer of the pill to control the diffusion of drugs in the pill so as to improve the efficacy.
The biocompatibility of medical polymer materials in contact with blood can be improved by adsorption, interception and grafting of two amphiphilic copolymers containing CARBOWAX Polyethylene Glycol 8000 on the surface of medical polymers.

CARBOWAX Polyethylene Glycol 8000 can make the membrane of the alkanol contraceptive pill.
CARBOWAX Polyethylene Glycol 8000 can make hydrophilic anticoagulant polyurethane.
CARBOWAX Polyethylene Glycol 8000is an osmotic laxative.

CARBOWAX Polyethylene Glycol 8000 can increase osmotic pressure and absorb moisture in the intestinal cavity, which makes the stool soften and increase in volume, resulting in bowel movement and defecation.
CARBOWAX Polyethylene Glycol 8000 nontoxic and gelatinous nature can be used as a component of denture fixer.
PEG 4000 and PEG 6000 are commonly used to promote cell fusion or protoplast fusion and help organisms (such as yeasts) to take DNA in transformation.

CARBOWAX Polyethylene Glycol 8000 absorbs water from the solution, so it is also used to concentrate the solution.
CARBOWAX Polyethylene Glycol 8000 are widely used in a variety of pharmaceutical formulations, including parenteral, topical, ophthalmic, oral, and rectal preparations. CARBOWAX Polyethylene Glycol 8000 has been used experimentally in biodegradable polymeric matrices used in controlled-release systems.

CARBOWAX Polyethylene Glycol 8000s are stable, hydrophilic substances that are essentially nonirritant to the skin;They do not readily penetrate the skin, although the CARBOWAX Polyethylene Glycol 8000s are water-soluble and are easily removed from the skin by washing, making them useful as ointment bases.
Solid grades are generally employed in topical ointments, with the consistency of the base being adjusted by the addition of liquid grades of CARBOWAX Polyethylene Glycol 8000.
Mixtures of CARBOWAX Polyethylene Glycol 8000s can be used as suppository bases,for which they have many advantages over fats. 

Safety Profile CARBOWAX Polyethylene Glycol 8000:
Topical preparations containing CARBOWAX Polyethylene Glycol 8000s should therefore be used cautiously in patients with renal failure, extensive burns, or open wounds.
CARBOWAX Polyethylene Glycol 8000s are widely used in a variety of pharmaceutical formulations. 
Generally, they are regarded as nontoxic and nonirritant materials.

Adverse reactions to CARBOWAX Polyethylene Glycol 8000s have been reported, the greatest toxicity being with glycols of low molecular weight. 
However, the toxicity of glycols is relatively low.
CARBOWAX Polyethylene Glycol 8000s administered topically may cause stinging, especially when applied to mucous membranes. 

Hypersensitivity reactions to CARBOWAX Polyethylene Glycol 8000s applied topically have also been reported, including urticaria and delayed allergic reactions.
The most serious adverse effects associated with CARBOWAX Polyethylene Glycol 8000s are hyperosmolarity, metabolic acidosis, and renal failure following the topical use of CARBOWAX Polyethylene Glycol 8000s in burn patients. 

Oral administration of large quantities of CARBOWAX Polyethylene Glycol 8000s can have a laxative effect. 
Therapeutically, up to 4 L of an aqueous mixture of electrolytes and high-molecular-weight CARBOWAX Polyethylene Glycol 8000 is consumed by patients undergoing bowel cleansing.